dactinomycin has been researched along with Experimental Neoplasms in 356 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 349 (98.03) | 18.7374 |
| 1990's | 4 (1.12) | 18.2507 |
| 2000's | 3 (0.84) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Atherton, E; Kondo, M; Meienhofer, J; Moore, S; Patel, RP | 1 |
| Bisagni, E; Chermann, JC; Ducrocq, C; Pochon, F; Rivalle, C; Tambourin, P; Tourbez-Perrin, M; Wendling, F | 1 |
| Burke, PJ; Friedlos, F; Knox, RJ; Mauger, AB; Somani, HH | 1 |
| MERKER, PC; PALM, JE; TELLER, MN; WOOLLEY, GW | 1 |
| HACKMANN, C | 3 |
| NITTA, K; TAKEUCHI, T; UMEZAWA, H; YAMAMOTO, T | 1 |
| NISHIBORI, A | 1 |
| GREGORY, FJ; HATA, T; PUGH, LH; THIELEN, R | 1 |
| HASEGAWA, S; NAKASEKO, H; OHASHI, I; SAKAI, F; TANAKADATE, Y | 1 |
| NISHIBORI, A; OOTA, K; TAKAHASHI, N | 1 |
| HAYASHI, Y; NISHIBORI, A; OOTA, K | 1 |
| HACKMANN, C; SCHMIDT-KASTNER, G | 1 |
| DIPAOLO, JA; MOORE, GE; NIEDBALA, TF | 1 |
| BORIC, F; IVANKOVIC, S; SEEMAYER, N | 2 |
| CH'EN, JT; CHOU, CH; HSU, B; KOO, SN; LI, WY; LIU, MC; LU, KH; SHEN, LC; WANG, TY | 1 |
| CHAN, PY; LIEBNER, EJ | 1 |
| GOLDSTEIN, MN; JOURNEY, LJ; SLOTNICK, IJ | 1 |
| DIPAOLO, JA | 1 |
| PUGH, LH; SOLOTOROVSKY, M | 1 |
| D'ANGIO, GJ; FARBER, S; HANDLER, AH; MADDOCK, CL | 1 |
| MOL'KOV, IuN | 1 |
| TIMOFEEVSKAIA, EA | 2 |
| BATES, L; KULKA, P; SAFIER, S; SATTERWHITE, H; SOLNEY, E; TARNOWSKI, G | 1 |
| CLINE, MJ; EASON, R; SMELLIE, RM | 1 |
| GEORGIEV, GP; LERMAN, MI; SAMARINA, OP; SEVERTZOV, AN; SMIRNOV, MN | 1 |
| KEIR, HM; OMURA, H; SHEPHERD, JB | 1 |
| DYER, HM; GULLINO, PM; MORRIS, HP | 1 |
| HANDLER, AH; SARRIS, TG; WILLS, C | 1 |
| KONDO, T | 1 |
| MCCONNELL, B; SOKOLOFF, B | 1 |
| BONDAREVA, AS; KUTCHKAREV, RN; MASAYEVA, VG; MAYEVSKY, MM; MOLKOV, YN; ROMANENKO, EA; TALYSINA, VA; TIMOFEYEVSKAYA, EA; URASOVA, AP; VYASOVA, OI | 1 |
| AKOPYANTS, SS; BELOVA, ZN; EBERT, MK; GOSHEVA, AE; GRACHEVA, NP; KHARITONOVA, AM; PLANELLES, JJ; SILAEV, AB; SOLOVYEVA, YV | 1 |
| DUKAT, EG; KJELLBERG, RN; MARK, VH; SOLOWAY, AH | 1 |
| BROCKMAN, RW | 1 |
| BACKMANN, R | 1 |
| CHOU, CH; HSU, B; JEN, YF; KAO, YS; LI, SW; LIU, MC; OWEN, TY; PAN, PC; SHEN, ML; TSAI, JS | 1 |
| GELBOIN, HV; KLEIN, M | 1 |
| CLAPP, P; CLARKSON, B; LAWRENCE, W; NICKSON, JJ; TAYAO, MS; TYREE, EB | 1 |
| CSANYI, E; HORVATH, P; INSTITORIS, L | 1 |
| ROTH, JS | 1 |
| EASON, R; SMELLIE, RM | 1 |
| FUKUI, N; HASEGAWA, S; MIURA, Y; MORIYAMA, Y | 1 |
| Han, MY; Hong, SH; Jeong, MJ; Kim, HK; Kim, HM; Kong, MY; Kwon, BM; Son, KH | 1 |
| Asada, H; Harada, Y; Imanishi, J; Ishii, M; Itoh, Y; Iwai, M; Kishida, T; Mazda, O; Okanoue, T; Shin-Ya, M | 1 |
| Arefolov, VA; Brzheskiĭ, VV | 1 |
| Bruce, WR | 1 |
| Burdon, RH; Lal, BM | 1 |
| Meyskens, FL; Russell, DH; Scott, KF | 1 |
| Aksenova, NN; Sleptsova, LA; Tsikarishvili, TN | 1 |
| Shu, RS; Wang, ZW; Xu, B | 1 |
| Crawford, EJ; Fowler, JS; Friedkin, M; Gallagher, BM; Goldin, A; Lambrecht, RM; MacGregor, RR; Shiue, CY; Wodinsky, I; Wolf, AP | 1 |
| Block, NL; Claflin, AJ; Greenstein, DB; Irvin, GL; Pollack, A; Prudhomme, DL | 1 |
| Tank, AW; Weiner, N | 1 |
| Kedar, A; McGarry, M; Moore, R; Murphy, GP; Williams, P | 1 |
| Kline, EL; Montefiori, DC | 1 |
| Bellino, FL; Hussa, RO | 1 |
| Kimura, S; Okazaki, K; Tanaka, S; Yoshida, N | 1 |
| Bakker, GH; Rommerts, FF; van der Molen, HJ | 1 |
| Speiser, P | 1 |
| Matthews, N | 1 |
| Rubenchik, BL | 1 |
| Dahllöf, B; Levan, G; Martinsson, T | 1 |
| Hershman, JM; Melmed, S; Park, J | 1 |
| Lund-Andersen, C; Nissen, NI; Skovsgaard, T | 1 |
| Fisch, H; Gifford, GE | 1 |
| Bakker, GH; Hoogerbrugge, JW; Rommerts, FF; van der Molen, HJ | 1 |
| Kakpakova, ES; Malalhova, EM; Massino, IuS | 1 |
| Beck, G; DiStefano, JF; Lysik, R; Zucker, S | 1 |
| Ishige, H; Katoh, T; Kobayashi, O; Takamizawa, H; Tanaka, N; Tokita, H | 2 |
| Richie, JP | 1 |
| Crish, JF; Krill, D; Wessels, BW | 1 |
| Drago, JR; Gershwin, ME; Goldman, LB; Worgul, T | 1 |
| Allen, TM; Gyorffy, E; Mausolf, S; McAllister, L | 1 |
| Kedar, A; Mayhew, EG; Moore, RH; Murphy, GP | 1 |
| Kaz'min, SD | 1 |
| Brodeur, GM; Green, AA; Houghton, JA; Houghton, PJ | 1 |
| Leibson, PJ; Loken, MR; Schreiber, H; Shapiro, SJ | 1 |
| Boden, JA; Kaye, SB | 1 |
| Drago, JR; Gershwin, ME; Goldman, LB | 2 |
| Ohanian, SH; Schlager, SI | 1 |
| Backenstoss, V; Hirsch, HH; Moroni, C; Nair, AP | 1 |
| Feleszko, W; Giermasz, A; Gołab, J; Jakóbisiak, M; Kuc, K; Lasek, W; Stokłosa, T; Wańkowicz, A; Zagozdzon, R | 1 |
| Bielecki, D; Hurta, RA | 1 |
| Cantor, MH; Grodin, M; Nystrom, R; Oppenheimer, SB; Scordato, J | 1 |
| Mattern, J; Volm, M; Wayss, K | 1 |
| Cohen, SC; Gabelnick, HL; Goldin, A; Johnson, RK | 1 |
| Migita, S; Natsu-ume, S; Ono, S | 1 |
| Borsos, T; Ohanian, SH; Segerling, M | 3 |
| Kuwata, T; Tomita, Y | 1 |
| Fuhr, JE; Overton, M; Townes, T; Yang, TJ | 1 |
| Borisov, VI | 1 |
| Busch, H; Busch, RK; Daskal, Y; Merski, J; Smetana, K | 1 |
| Beliaeva, ID; Nefelova, MV; Prokopenko, VM | 1 |
| Nikulina, LB | 1 |
| Edgar, DH; Thoenen, H | 1 |
| Kałuza, J | 1 |
| Faufmann, M; MAttern, J; Volm, M; Wayss, K | 1 |
| Casey, AE; Griswold, DP; Prejean, JD; Weisburger, EK; Weisburger, JH; Wood, HB | 1 |
| Fischer, JJ; Lo, PS; Moulder, JE | 1 |
| Borek, E; Mays, LL; Sharma, OK | 1 |
| Aczel, J; Enesco, HE | 2 |
| Ballard, FJ; Gunn, JM; Hanson, RW; Reshef, L; Tilghman, SM | 1 |
| Elias-Bishko, S; Epstein, D; Hershko, A | 1 |
| Murphy, GP; Williams, PD | 1 |
| Homsy, YL; Lattimer, JK; Tannenbaum, M; Tomashefsky, P | 1 |
| Bast, RC; Borsos, T; Greene, SL; Ohanian, SH; Rapp, HJ; Segerling, M; Zbar, B | 1 |
| Tevethia, MJ; Tevethia, SS | 1 |
| Canellakis, ES; Fong, WF; Heller, JS | 1 |
| Brown, JL; Prasad, KN; Sahu, SK; Sinha, PK | 1 |
| Canellakis, ZN; Theoharides, TC | 1 |
| Lyons, RT; Pitot, HC | 1 |
| Hayashi, H; Ishihara, H; Ishimaru, Y; Kudo, K | 1 |
| Roth, JJ; Roth, JS | 1 |
| Gaitskhoki, VS; Kisselev, OI; Pozharisski, KM; Shalumovich, WN; Shaposhnikov, JD | 1 |
| Ahmed, NK; Shanker, G; Sharma, RK | 1 |
| Gasic, GJ; Gasic, TB; Jimenez, SA | 1 |
| Pitot, HC | 2 |
| Borsos, T; Boyle, MD; Ohanian, SH; Schlager, SI | 1 |
| Duchesne, MC; Mamont, PS; McCann, PP; Tardif, C | 1 |
| Brinkley, B; Dabbous, MK; Roberts, AN | 1 |
| Arbuzov, VA | 1 |
| Cronenberger, JH; Magee, WE; Thor, DE | 1 |
| Murty, CN; Sidransky, H; Verney, E | 1 |
| Acs, G; Christman, J; Kyner, D; Newcomb, EW; Silagi, S; Silverstein, SC | 1 |
| Piessens, WF; Sharma, SD | 1 |
| Broder, LE; Rosen, SW; Weintraub, BD | 1 |
| Hozumi, M | 2 |
| Soloway, MS | 1 |
| Kaplan, HS | 1 |
| Hozumi, M; Okabe, J; Sugiyama, K | 1 |
| Beutler, WJ; Biedler, JL; Peterson, RH | 1 |
| Kauffman, W; Slagel, DE | 1 |
| Bienkowski, M; Dunn, JR; Honn, KV; Marnett, LJ; Morgan, LR | 1 |
| Laster, WR; Rose, WC; Schabel, FM; Veras, GH | 1 |
| Craig, N | 1 |
| Hayashi, H; Kameya, T; Mukojima, T; Shimosato, Y | 1 |
| Blümel, G; Osterkamp, U; Stavrou, D; Wriedt-Lübbe, I; Zänker, KS | 1 |
| Hertz, R; Knecht, M | 1 |
| Berebbi, M; Fischer, P; Foa, C; Simonetti, J; Vetterlein, M | 1 |
| Johnson, RJ; Pasternack, GR; Shin, HS | 1 |
| Block, NL; Camuzzi, F; Claflin, A; Politano, VA; Stover, B; Troner, M | 1 |
| Izawa, M; Sameshima, M | 1 |
| Stukov, AN | 1 |
| Pawelek, J; Wong, G | 2 |
| Copeland, M; Kondo, M; Meienhofer, J; Moore, S | 1 |
| Philips, FS; Sternberg, SS | 1 |
| Friedman, SJ; Kimball, T; Skehan, PJ; Trotter, CD | 1 |
| Dämianova, M; Stoychkov, J | 1 |
| Canellakis, ES; Chen, TK; Fico, RM | 1 |
| Biedler, JL; Papahadjopoulos, D; Poste, G; Vail, WJ | 1 |
| Babichev, VA; Nikitin, AV | 1 |
| Bolan, G; Lippman, ME; Monaco, ME; Osborne, CK | 1 |
| Konopliannikov, AG | 1 |
| Barra, Y; Berebbi, M; Imbert, I | 1 |
| Stevens, J; Stevens, YW | 1 |
| Gregoriadis, G; Neerunjun, ED | 1 |
| Bleehen, NM; Twentyman, PR | 1 |
| Carchman, RA; Dewey, WL; Friedman, MA; Harris, LS; Munson, AE | 1 |
| Biedler, JL; Peterson, RH; Riehm, H; Spengler, BA | 1 |
| Chodera, A; Hladoń, B | 1 |
| Marks, TA; Venditti, JM | 1 |
| Marquardt, H; Philips, FS; Sternberg, SS | 1 |
| Vol'pe, EA | 1 |
| Furuya, M; Kano, E | 1 |
| Kamat, JP; Narurkar, LM; Narurkar, MV | 1 |
| Bersani, L; Colotta, F; Mantovani, A; Polentarutti, N; Poli, G | 1 |
| Biedler, JL; Chang, TD; Meyers, MB; Schneider, KA; Spengler, BA | 1 |
| Gallily, R; Gifford, GE; Loewenstein, J; Yamin, A | 1 |
| Di Luzio, NR; Sherwood, ER; Williams, DL | 1 |
| Bertram, JS | 1 |
| Abe, S; Gatanaga, T; Mizuno, D; Takahashi, K; Yamazaki, M | 1 |
| Ikenami, M; Mizuno, D; Yamazaki, M | 1 |
| Yamazaki, M | 1 |
| Dahllöf, B; Leffler, H; Levan, G; Martinsson, T; Wettergren, Y | 1 |
| Kenney, FT; Lee, KL | 1 |
| Seidel, HJ | 2 |
| Kann, HE; Kohn, KW; Snyder, AL | 1 |
| Cohn, Z; Gordon, S | 1 |
| Kanamoto, Y | 1 |
| Denisova, SI; Gogoleva, IA; Lupinosov, IuV; Syrkin, AB | 1 |
| Huot, J; Nosal, G; Radouco-Thomas, C | 1 |
| Martin, DW; Owen, NT | 1 |
| Martin, TE; McCarthy, BJ | 1 |
| Eckel, H; Hilfrich, J; Reznik, G; Schüller, H | 1 |
| Goerttler, K; Kaufmann, M; Mattern, J; Volm, M; Wayss, K | 1 |
| Miyaki, M; Moroashi, S; Ono, T | 1 |
| Atherton, E; Meienhofer, J | 1 |
| Pitot, HC; Weiss, JW | 1 |
| Bagshaw, MA; Goffinet, DR | 1 |
| Granner, D; Sellers, L | 1 |
| Barnett, CA; McKibbin, JB; Wicks, WD | 1 |
| Becker, JE; Bushnell, DE; Potter, VR | 1 |
| Becker, JE; Bushnell, DE; Potter, VR; Yager, JD | 1 |
| Goldenberg, DM; Goldenberg, H; Witte, S; Wüst, H | 1 |
| Ernstberger, W; Goldenberg, DM; Witte, S | 1 |
| Althoff, J; Mohr, U; Pielsticker, K; Wiener, O | 1 |
| Gelboin, HV | 1 |
| Goldenberg, DM; Hartmann, G; Hindringer, B; Witte, S | 1 |
| Krasil'nikov, NA; Kuimova, TF | 1 |
| Norpoth, K; Rauen, HM | 1 |
| Maezaeva, VG | 1 |
| Avdeeva, IA; Mazaeva, VG; Nivinskaia, MM; Romanenko, EA; Sedakova, LA | 1 |
| Plagemann, PG | 2 |
| Akopyants, SS; Kuznetsova, VS; Nefelova, MV; Orlova, TI; Silayev, AB; Zubova, OV | 1 |
| Sugiura, K | 2 |
| Goldenberg, DM; Witte, S | 1 |
| Harada, Y; Katagiri, K; Sunagawa, N | 1 |
| Wüst, GP | 1 |
| Chernyakhovskaya, IY; Kadaghidze, ZG; Rimalis, RT; Svet-Moldavsky, GJ | 1 |
| Goldenberg, DM; Goldenberg, H | 1 |
| Kuroki, T | 1 |
| Potapov, SL | 1 |
| Bancroft, FC; Goldlust, MB; Mayer, MM; Rommel, FA; Tashjian, AH | 1 |
| Berenbaum, MC; Bundick, RV; Reittie, JR; Sheard, CE | 1 |
| Cappuccino, JG; Schmid, FA; Stock, CC; Tarnowski, GS | 1 |
| Bradner, WT; Pindell, MH | 1 |
| Kummer, D | 1 |
| DeKernion, JB; Persky, L; Resnick, MI | 1 |
| Bhuyan, BK; Fraser, TJ; Scheidt, LG | 1 |
| Arima, T; Fujii, S; Okuda, H; Shirasaka, T | 1 |
| Potter, VR; Webb, TE | 1 |
| Plagemann, PG; Swim, HE | 2 |
| Sabin, AB | 1 |
| Bosisio-Bestetti, M; Sirtori, C | 1 |
| Keir, HM | 1 |
| Webb, TE | 1 |
| Ichii, S; Omata, S | 1 |
| Kwan, SW; Morris, HP; Webb, TE | 1 |
| Ip, PM; Sung, SC | 1 |
| Busch, H; Choi, YC | 1 |
| Miura, Y | 1 |
| Hirono, I; Kachi, H; Nishio, Y; Shibuya, C | 1 |
| Van Duuren, BL | 1 |
| Korbecki, M; Mahy, BW; Plagemann, PG; Ward, GA | 1 |
| Huppert, J; Semmel, M | 2 |
| Sakurai, Y; Tashiro, T | 1 |
| Raina, PN; Rosen, F | 2 |
| Bernhard, W; Zotikov, L | 1 |
| Morris, HP; Potter, VR; Watanabe, M | 1 |
| Hreshchyshyn, MM; Kawai, N | 1 |
| Pitot, HC; Sladek, NE | 1 |
| Kowal, J | 1 |
| Defendi, V; Girardi, AJ | 1 |
| Morris, HP; Wu, C | 1 |
| Frederiksen, S; Hellung-Larsen, P; Tonnesen, T | 1 |
| Gaĭtskhoki, VS; Kiselev, OI; Shaposhnikov, IaD | 1 |
| Ferdinandus, JA; Morris, HP; Weber, G | 1 |
| Mallucci, L; Skehel, JJ | 1 |
| Prutkin, L | 2 |
| Dobos, P; Kerr, IM; Martin, EM | 1 |
| Arima, T; Fujii, S; Masaka, M | 1 |
| Inoue, H; Kaplan, JH; Pitot, HC | 1 |
| Mallucci, L; Poste, GH; Wells, V | 1 |
| Higashi, T; Kashiwagi, K; Tobe, T | 1 |
| Bush, IM; Javadpour, N | 1 |
| Busch, H; Okada, S | 1 |
| Prasad, KN; Sheppard, JR | 1 |
| Faulkner, CS; Harris, ED; Wood, S | 1 |
| Belousova, AK | 1 |
| Criss, WE | 1 |
| Blackledge, A; Hogan, B | 1 |
| Brailovsky, C; Lallier, R; Nigam, VN | 1 |
| Barski, G; Blanchard, MG; Leon, B; Youn, JK | 1 |
| Hanczakowska, M; Ptak, W; Zembala, M | 1 |
| Dybing, E | 2 |
| Skipper, HE | 1 |
| Hoogenraad, NJ; Lee, DC | 1 |
| Husk, M; Mount, BM; Thelmo, WL | 1 |
| McAllister, RM | 1 |
| Keller, R | 1 |
| Kirsten, ES; Watson, JA | 1 |
| Cremisi, C; Sonenshein, GE; Tournier, P | 1 |
| Katsuta, H; Nitta, K; Nose, K; Takaoka, T | 1 |
| Cassingena, R; Estrade, S; Lavialle, C; Lazar, P; Suarez, HG; Wicker, R | 2 |
| Peterkofsky, B; Tomkins, GM | 1 |
| Bresler, MA; Martin, DW; Tomkins, GM | 1 |
| Gelehrter, TD; Tomkins, GM | 1 |
| Auricchio, F; Martin, D; Tompkins, G | 1 |
| Pitot, HC; Poirier, LA | 1 |
| Levitan, IB; Morris, HP; Webb, TE | 1 |
| Benedict, WF; Nebert, DW; Thompson, EB | 1 |
| Becker, JE; Bushnell, DE; Butcher, FR; Potter, VR | 1 |
| Artamonova, VA; Kakushkina, ML; Malenkov, AG; Slivinsky, GG; Voejkov, VL | 1 |
| Husk, M; Mount, BM | 1 |
| Adams, RA; Flowers, A; Merk, LP; Sundeen, R | 1 |
| Prasad, KN | 1 |
| Mallucci, L; Wells, V; Young, MR | 1 |
| Gelboin, HV; Kinoshita, N; Wiebel, FJ | 1 |
| Andersson, J; Buxbaum, J; Citronbaum, R; Douglas, S; Forni, L; Melchers, F; Pernis, B; Stott, D | 1 |
| Bengmark, S; Fredlund, P; Hafström, LO; Vang, J | 1 |
| Cooke, A; Dray, S; Giacomoni, D; Heller, P; Wang, SR; Yakulis, V | 1 |
| Webb, M | 1 |
| Cikes, M; Klein, G | 1 |
| Bokhon'ko, AI; Panchenko, LF; Schuppe, NG; Stelletskaya, NV; Syrota, TV | 1 |
| Barski, G; Blanchard, MG; Hémon, D; Léon, B | 1 |
| Lehmeyer, JE; MacLeod, RM | 1 |
| Melchionne, S; Van Duuren, BL | 1 |
| Nagata, C | 1 |
| Vályi-Nagy, T | 1 |
| Barski, G; Berebbi, M | 1 |
| Syrkin, AB | 1 |
| Honohan, T; Katz, C; Schroeder, M; Segal, A; Van Duuren, BL | 1 |
| Kelley, RO | 1 |
| Fujita, H; Hanawa, Y; Kimura, K; Sawabe, T | 1 |
| Izawa, M; Kawashima, K; Sato, S | 1 |
| Morita, T; Muto, M | 1 |
| Bobikov, EV; Radzievskaia, VV; Sazykin, IuO; Terent'eva, TG | 1 |
| Bates, RR; Gelboin, HV; Klein, M | 1 |
| Ambaye, RY; Schwartz, HS; Sodergren, JE | 1 |
| Alexander-Jackson, E; Livingston, AM; Livingston, VW; Wolter, GH | 1 |
| Deitch, AD; Godman, GC | 1 |
| Bose, S; Chakraborty, B; Chowdhury, RJ; Das, S | 1 |
| Harris, C; Reddy, J; Svoboda, D | 1 |
| Bresnick, E; Burleson, SS | 1 |
| Garancis, JC; Hussa, RO; Mattingly, RF; Pattillo, RA; Ruckert, AC | 1 |
| Albrecht, AM; Biedler, JL; Riehm, H; Sobel, JS | 1 |
| Azuma, H; Ito, E; Mori, T; Noguchi, S; Takai, S | 1 |
| Weisburger, EK; Weisburger, JH; Yamamoto, RS | 1 |
| Bose, S; Coutinho, WG; Gothoskar, BP; Nayak, SK; Ranadive, KJ | 1 |
| Bates, RR; Counts, WB; Dingman, CW; Gelboin, HV; Wortham, JS | 1 |
| Boutwell, RK; Colburn, NH; Hennings, H; Smith, HC | 1 |
| Granoff, A; Kucera, LS | 1 |
| Ledinko, N; Toolan, HW | 1 |
| Hogan, BL; Korner, A | 1 |
| Dirks, VA; Kennedy, BJ; McNulty, TB; Yarbro, JW | 1 |
| Katz, C; Melchionne, S; Sivak, A; Van Duuren, BL | 1 |
| Gregg, EC; Rosenberg, HM | 1 |
| Baserga, R; McDonough, M; Sasaki, T; Shimkin, MB; Thatcher, D; Wieder, R | 1 |
| Bather, R; Buck, BM | 1 |
| Jull, JW | 1 |
| Cassingena, R; Simard, R | 1 |
| Izawa, M; Kawashima, K | 1 |
| McCollister, SB; Pietsch, P | 1 |
| Mainwaring, WI; Williams, DC | 1 |
| Sartorelli, AC; Tsunamura, S | 1 |
20 review(s) available for dactinomycin and Experimental Neoplasms
| Article | Year |
|---|---|
MECHANISMS OF RESISTANCE TO ANTICANCER AGENTS.
Topics: Alkylating Agents; Antineoplastic Agents; Azaserine; Dactinomycin; DNA; Drug Resistance; Drug Resistance, Microbial; Drug Tolerance; Folic Acid; Humans; Leucine; Metabolism; Mitomycin; Mitomycins; Neoplasms; Neoplasms, Experimental; Pharmacology; Purines; Pyrimidines; RNA; Steroids; Tissue Culture Techniques | 1963 |
Soviet antitumor preparations.
Topics: Animals; Antineoplastic Agents; Aziridines; Butylated Hydroxytoluene; Dactinomycin; Daunorubicin; Humans; Melphalan; Methylnitrosourea; Neoplasms, Experimental; Nitrogen Mustard Compounds; Olivomycins; Organophosphorus Compounds; Phenylalanine; Prospidium; Pyrimidines; Spiro Compounds; Streptonigrin; Tegafur; Triethylenephosphoramide; Uracil | 1977 |
[On anticarcinogens and cocarcinogens (author's transl)].
Topics: Animals; Antineoplastic Agents; Antioxidants; Carcinogens; Dactinomycin; Leupeptins; Mice; Neoplasms, Experimental; Protease Inhibitors; Rabbits; Skin Neoplasms; Stomach Neoplasms | 1978 |
Intravesical and systemic chemotherapy of murine bladder cancer.
Topics: Animals; Antineoplastic Agents; BCG Vaccine; Carcinoma, Transitional Cell; Cisplatin; Cyclophosphamide; Dactinomycin; Doxorubicin; Drug Therapy, Combination; Ethoglucid; FANFT; Female; Fluorouracil; Mice; Mice, Inbred C3H; Neoplasm Transplantation; Neoplasms, Experimental; Podophyllotoxin; Thiotepa; Urinary Bladder Neoplasms | 1977 |
1977 Henry H. Janeway lecture: fundamental mechanisms in combined modality therapy of cancer.
Topics: Animals; Antineoplastic Agents; Bromodeoxyuridine; Dactinomycin; DNA Repair; DNA, Neoplasm; Electrons; Fluorouracil; Humans; Hyperthermia, Induced; Hypoxia; Idoxuridine; Immunotherapy; Mice; Neoplasms; Neoplasms, Experimental; Radiation-Protective Agents; Radiation-Sensitizing Agents; Radiotherapy Dosage; Tourniquets; Ultrasonic Therapy | 1977 |
[A review of experimental thermochemotherapy in cultured cells].
Topics: Animals; Antineoplastic Agents; Bleomycin; Cell Membrane Permeability; Cells, Cultured; Combined Modality Therapy; Dactinomycin; Drug Interactions; Hot Temperature; Humans; Neoplasms; Neoplasms, Experimental; Oxygen | 1985 |
Neoplastic transformation in cell cultures: in-vitro/in-vivo correlations.
Topics: Animals; Antigens, Neoplasm; Ascorbic Acid; Biotransformation; Calcium; Carcinogens; Cell Adhesion; Cell Cycle; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Culture Media; Dactinomycin; DNA; Glucocorticoids; Growth Substances; Mice; Neoplasms, Experimental; Oncogenes; Phorbol Esters; Protease Inhibitors; Retinoids; Saccharin; Structure-Activity Relationship | 1985 |
Structure-activity relationships in the actinomycins.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Bacteria; Cells, Cultured; Chromatophores; Circular Dichroism; Dactinomycin; DNA; Genes; Magnetic Resonance Spectroscopy; Models, Chemical; Molecular Conformation; Neoplasms, Experimental; Optical Rotatory Dispersion; Peptides; Structure-Activity Relationship; Terminology as Topic; Virus Replication; X-Ray Diffraction | 1973 |
Clinical use of radiation sensitizing agents.
Topics: Animals; Antimetabolites, Antineoplastic; Bleomycin; Bromodeoxycytidine; Bromodeoxyuridine; Bromouracil; Carcinoma, Squamous Cell; Dactinomycin; Dose-Response Relationship, Radiation; Floxuridine; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Idoxuridine; Neoplasms; Neoplasms, Experimental; Radiation-Sensitizing Agents | 1974 |
[Chemical carcinogenesis in vitro. 2].
Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Culture Techniques; Dactinomycin; DNA; Genes; HeLa Cells; Hydroxyurea; Mutation; Neoplasms, Experimental; Niacinamide; Puromycin; Quinolines; RNA; Transformation, Genetic | 1970 |
DNA polymerases from mammalian cells.
Topics: Animals; Culture Techniques; Dactinomycin; DNA; Escherichia coli; Fibroblasts; Neoplasms, Experimental; Nucleotidyltransferases; Simplexvirus; Thymus Gland | 1965 |
Endoplasmic reticulum and phenotypic variability in normal and neoplastic liver.
Topics: Adrenal Glands; Animals; Carcinoma, Hepatocellular; Cell Differentiation; Cell Transformation, Neoplastic; Dactinomycin; Endoplasmic Reticulum; L-Serine Dehydratase; Liver; Liver Neoplasms; Models, Biological; Neoplasms, Experimental; Phenotype; Rats; RNA; RNA, Messenger; RNA, Neoplasm; Templates, Genetic | 1969 |
Tumor-promoting agents in two-stage carcinogenesis.
Topics: Animals; Benz(a)Anthracenes; Carcinogens; Croton Oil; Culture Techniques; Dactinomycin; Esters; Hydrocarbons; Lysosomes; Mice; Neoplasms, Experimental; Nicotiana; Plants, Toxic; Simian virus 40; Skin; Skin Neoplasms; Species Specificity | 1969 |
[Deoxythimidine kinase].
Topics: Adrenocorticotropic Hormone; Animals; Carcinoma, Ehrlich Tumor; Cell Division; Chromatography, DEAE-Cellulose; Cricetinae; Dactinomycin; DNA; Enzyme Induction; Escherichia coli; Growth Hormone; Hepatectomy; Liver Neoplasms; Liver Regeneration; Neoplasms, Experimental; Nucleosides; Nucleotides; Rats; Sarcoma, Yoshida; Thymidine; Thymidine Kinase; Virus Diseases | 1971 |
[Molecular basis of the relation between the cytotoxic effect of antineoplastic compounds and the cell cycle phase].
Topics: Adenocarcinoma; Adrenocorticotropic Hormone; Alkylating Agents; Androgens; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Culture Techniques; Cyclic AMP; Dactinomycin; DNA Replication; DNA, Neoplasm; Estrogens; Fluorouracil; Glucagon; Glucocorticoids; Mathematics; Methotrexate; Mitosis; Molecular Biology; Neoplasm Transplantation; Neoplasms, Experimental; Receptors, Drug; RNA, Neoplasm; Sarcoma, Experimental | 1972 |
Microsomal aryl hydrocarbon hydroxylases: on their role in polycyclic hydrocarbon carcinogenesis and toxicity and the mechanism of enzyme induction.
Topics: Animals; Benz(a)Anthracenes; Benzopyrenes; Binding Sites; Carbon Isotopes; Carcinogens; Centrifugation, Density Gradient; Cricetinae; Cycloheximide; Dactinomycin; Electrophoresis; Embryo, Mammalian; Enzyme Induction; Flavonoids; Hybridization, Genetic; Kinetics; Liver; Mice; Mice, Inbred Strains; Microsomes, Liver; Mixed Function Oxygenases; Neoplasms, Experimental; RNA; Tritium; Uridine | 1972 |
Present experiences with hepatic dearterialization in liver neoplasm.
Topics: Adult; Aged; Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Catheterization; Dactinomycin; Female; Fluorouracil; Hepatic Artery; Humans; Ligation; Lipids; Liver Circulation; Liver Neoplasms; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasms, Experimental; Rats; Remission, Spontaneous | 1974 |
Inhibition of tumorigenesis.
Topics: Animals; Breast Neoplasms; Carcinogens; Chemical Phenomena; Chemistry; Dactinomycin; DNA, Neoplasm; Enzyme Induction; Isonicotinic Acids; Liver Neoplasms; Mammary Glands, Animal; Mice; Microsomes; Mustard Compounds; Neoplasms, Experimental; Progesterone; Quinolines; Rats; RNA, Neoplasm; Skin Neoplasms | 1969 |
[Interaction between chemical carcinogens and nucleic acids. 1. Theoretical basis of carcinogenesis].
Topics: Animals; Benz(a)Anthracenes; Benzopyrenes; Carcinogens; Chemical Phenomena; Chemistry; Dactinomycin; DNA; Humans; Methylcholanthrene; Neoplasms, Experimental; Nucleic Acids; Nucleotides; Spectrum Analysis | 1970 |
[Instability of phenotypes of tumor cells--on decarcinogenesis].
Topics: Amphibians; Animals; Anura; Bromodeoxyuridine; Carcinogens; Cell Differentiation; Cell Fusion; Cell Membrane; Dactinomycin; Daunorubicin; Hexokinase; Humans; Isoenzymes; Mice; Neoplasm Regression, Spontaneous; Neoplasm Transplantation; Neoplasms; Neoplasms, Experimental; Nitrosourea Compounds; Phenotype; Quinolines | 1971 |
336 other study(ies) available for dactinomycin and Experimental Neoplasms
| Article | Year |
|---|---|
Synthesis and some properties and antitumor effects of the actinomycin lactam analog, (di(1-L-alpha, beta-diaminopropionic))actinomycin D1.
Topics: Animals; Antibiotics, Antineoplastic; beta-Lactams; Circular Dichroism; Dactinomycin; Leukemia L1210; Leukemia, Experimental; Male; Melanoma; Mice; Mice, Inbred Strains; Neoplasms, Experimental | 1976 |
Structure-activity relationships in a series of newly synthesized 1-amino-substituted ellipticine derivatives.
Topics: Alkaloids; Animals; Antineoplastic Agents; Cell Survival; Chemical Phenomena; Chemistry; Ellipticines; Lethal Dose 50; Mice; Neoplasms, Experimental; Structure-Activity Relationship | 1980 |
Self-immolative prodrugs: candidates for antibody-directed enzyme prodrug therapy in conjunction with a nitroreductase enzyme.
Topics: Animals; Antineoplastic Agents; Dactinomycin; Immunotoxins; Mice; Mice, Inbred BALB C; Molecular Structure; Neoplasms, Experimental; Nitroreductases; Prodrugs; Tumor Cells, Cultured | 1994 |
Effect of actinomycin D on two human tumors growing in conditioned rats.
Topics: Animals; Anti-Bacterial Agents; Antibiotics, Antitubercular; Dactinomycin; Humans; Neoplasms; Neoplasms, Experimental; Rats | 1957 |
[Experimental investigations on the effects of actinomycin C (HBF 386) in malignancies].
Topics: Animals; Anti-Bacterial Agents; Antibiotics, Antitubercular; Dactinomycin; Humans; Neoplasms; Neoplasms, Experimental | 1952 |
[HBF 386 (actinomycin C), a natural substance of cytostatic effect].
Topics: Animals; Anti-Bacterial Agents; Antibiotics, Antitubercular; Dactinomycin; Lymphatic System; Neoplasms, Experimental | 1953 |
Studies on the effects of actinomycin, cycloheximide, and other known antibiotics on Ehrlich carcinoma of mice.
Topics: Animals; Anti-Bacterial Agents; Cycloheximide; Dactinomycin; Mice; Neoplasms, Experimental | 1955 |
Studies on antitumor effect of actinomycin J.
Topics: Animals; Anti-Bacterial Agents; Dactinomycin; Humans; Neoplasms, Experimental | 1956 |
The effect of actinomycin D on experimental ascitic tumors in the mouse.
Topics: Animals; Anti-Bacterial Agents; Dactinomycin; Mice; Neoplasms, Experimental | 1956 |
[Cytostatic effect of antibiotics (actinomycin J, sarkomycin and pluramycin) on Yoshida ascites sarcoma cells].
Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Antineoplastic Agents; Ascites; Cytostatic Agents; Dactinomycin; Neoplasms, Experimental; Sarcoma | 1956 |
Experimental study on the oncostatic activity of actinomycin J. I. Histological findings of therapeutic effects on Ehrlich's mouse ascites carcinoma in the ddN strain mice.
Topics: Animals; Anti-Bacterial Agents; Ascites; Dactinomycin; Mice; Neoplasms, Experimental | 1957 |
Experimental study on the oncostatic activity of actinomycin J. II. Effects on the Yoshida ascites sarcoma in stock rats.
Topics: Animals; Anti-Bacterial Agents; Ascites; Dactinomycin; Neoplasms, Experimental; Rats; Sarcoma, Yoshida | 1957 |
[Cytostatic action of various new biosynthetic actinomycins in experimental tumors].
Topics: Animals; Antineoplastic Agents; Cytostatic Agents; Dactinomycin; Humans; Neoplasms, Experimental | 1957 |
Experimental studies with actinomycin D.
Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Dactinomycin; Humans; Neoplasms, Experimental | 1957 |
[Effect of actinomycin C on a transplantable lymphosarcoma of mice].
Topics: Animals; Anti-Bacterial Agents; Antibiotics, Antitubercular; Dactinomycin; Lymphoma; Lymphoma, Non-Hodgkin; Mice; Neoplasms, Experimental | 1957 |
[Research on the effect of actinomycin C on the Yoshida sarcoma of rats].
Topics: Animals; Anti-Bacterial Agents; Dactinomycin; Neoplasms, Experimental; Rats; Sarcoma, Experimental; Sarcoma, Yoshida | 1957 |
Actinomycin K; an antibiotic against tumor.
Topics: Animals; Anti-Bacterial Agents; Dactinomycin; Neoplasms; Neoplasms, Experimental | 1959 |
In vitro effects of irradiation combined with actinomycin D.
Topics: Animals; Dactinomycin; Humans; In Vitro Techniques; Neoplasms, Experimental; Radiation Effects | 1961 |
In vitro studies with HeLa cell line sensitive and resistant to actinomycin D.
Topics: Animals; Cell Line; Dactinomycin; HeLa Cells; Humans; In Vitro Techniques; Neoplasms, Experimental | 1960 |
The effect of actinomycins on experimental tumors.
Topics: Animals; Dactinomycin; Neoplasms, Experimental | 1960 |
Experimental evaluation of actinomycin D.
Topics: Animals; Dactinomycin; Neoplasms, Experimental | 1960 |
Comparative effects of actinomycins II, III, and IV on several ascitic tumors of mice.
Topics: Animals; Dactinomycin; Mice; Neoplasms; Neoplasms, Experimental | 1960 |
Biological studies of actinomycin D.
Topics: Animals; Dactinomycin; Neoplasms, Experimental | 1960 |
[Aurantin prevention of recurrence and metastasis after surgical removal of transplanted tumor].
Topics: Animals; Anti-Bacterial Agents; Dactinomycin; Neoplasm Recurrence, Local; Neoplasm Transplantation; Neoplasms; Neoplasms, Experimental | 1960 |
[Effect of aurantin on human tumor strain cultures].
Topics: Animals; Anti-Bacterial Agents; Antibiotics, Antitubercular; Dactinomycin; Dermatologic Agents; Neoplasms, Experimental | 1962 |
EFFECTS OF CHEMICAL TREATMENT IN VITRO OF NELSON MOUSE ASCITES TUMOR CELLS ON THEIR TRANSPLANTABILITY AND ON SOME INDICES OF GLUCOSE METABOLISM.
Topics: Animals; Antineoplastic Agents; Ascites; Aziridines; Carbohydrate Metabolism; Carbon Isotopes; Carboxylic Acids; Carcinoma, Ehrlich Tumor; Cyclopentanes; Dactinomycin; Glucose; In Vitro Techniques; Mechlorethamine; Methotrexate; Mice; Mitomycin; Mitomycins; Neoplasms, Experimental; Research; Urethane | 1963 |
RIBONUCLEIC ACIDS IN VIRUS-INFECTED AND UNINFECTED KREBS II ASCITES TUMOR CELLS.
Topics: Arboviruses; Ascites; Dactinomycin; DNA; DNA, Neoplasm; Encephalomyocarditis virus; Metabolism; Neoplasms; Neoplasms, Experimental; Nucleosides; Pharmacology; Research; RNA; RNA, Neoplasm; RNA, Viral; Tritium; Virus Cultivation | 1963 |
BIOSYNTHESIS OF MESSENGER AND RIBOSOMAL RIBONUCLEIC ACIDS IN THE NUCLEOLOCHROMOSOMAL APPARATUS OF ANIMAL CELLS.
Topics: Amnion; Carcinoma, Ehrlich Tumor; Cell Nucleus; Chromosomes; Dactinomycin; Liver; Metabolism; Neoplasms; Neoplasms, Experimental; Nucleoproteins; Pharmacology; Phosphorus Isotopes; Proteins; Rats; Research; RNA; RNA, Ribosomal; Tissue Culture Techniques | 1963 |
INHIBITION OF A MAMMALIAN DEOXYRIBONUCLEIC ACID NUCLEOTIDYLTRANSFERASE BY ACTINOMYCIN D.
Topics: Animals; Dactinomycin; DNA; DNA, Neoplasm; Enzyme Inhibitors; Mammals; Neoplasms; Neoplasms, Experimental; Nucleotides; Nucleotidyltransferases; Pharmacology; Phosphorus Isotopes; Research | 1963 |
TRYPTOPHAN PYRROLASE ACTIVITY IN TRANSPLANTED "MINIMAL-DEVIATION" HEPATOMAS.
Topics: Anti-Bacterial Agents; Carcinoma, Hepatocellular; Cortisone; Dactinomycin; Liver; Liver Neoplasms; Neoplasms; Neoplasms, Experimental; Oxidation-Reduction; Oxygenases; Pathology; Puromycin; Rats; Renal Artery; Research; Transplantation; Tryptophan; Tryptophan Oxygenase | 1964 |
CHEMOTHERAPY STUDIES ON PRIMARY TUMOR GRAFTS AND METASTASES IN HAMSTERS AND MICE.
Topics: Antineoplastic Agents; Cricetinae; Cyclophosphamide; Dactinomycin; Melphalan; Mice; Mitomycin; Mitomycins; Neoplasm Metastasis; Neoplasms; Neoplasms, Experimental; Pharmacology; Research; Sarcoma; Sarcoma, Experimental; Thiotepa | 1964 |
THE ADVERSE EFFECTS OF CANCER CHEMOTHERAPY.
Topics: Animals; Antineoplastic Agents; Azaguanine; Carcinoma, Ehrlich Tumor; Cortisone; Cyclophosphamide; Dactinomycin; Mechlorethamine; Mice; Mitomycin; Neoplasm Metastasis; Neoplasms; Neoplasms, Experimental; Pharmacology; Research; Sarcoma; Sarcoma, Yoshida; Thiotepa; Toxicology | 1964 |
HOST DEFENCE AND CHEMOTHERAPY IN EXPERIMENTAL CANCER.
Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Dactinomycin; Flavonoids; Lymphoma; Lymphoma, Non-Hodgkin; Mice; Mitomycin; Mitomycins; Mononuclear Phagocyte System; Neoplasms; Neoplasms, Experimental; Pharmacology; Polysaccharides; Rabbits; Research; Sarcoma 180; Trypan Blue; Zymosan | 1964 |
TUMOR-INHIBITING ACTION OF OLIVOMYCIN (16749) AND ANTIBIOTIC 2703 (CHRYSOMALLIN). (EXPERIMENTAL AND CLINICAL OBSERVATIONS).
Topics: Anti-Bacterial Agents; Antineoplastic Agents; Carcinoma; Dactinomycin; Lymphoma; Neoplasms; Neoplasms, Experimental; Olivomycins; Pharmacology; Rats; Research; Sarcoma; Sarcoma, Experimental | 1964 |
AURANTIN--A COMPLEX ANTIBIOTIC SUBSTANCE OF THE ACTINOMYCIN GROUP: ITS PROPERTIES AND RESULTS OF CLINICAL TRIALS ON VARIOUS TYPES OF NEOPLASMS.
Topics: Adenocarcinoma; Adrenal Cortex Hormones; Animals; Anti-Bacterial Agents; Antineoplastic Agents; Brain Neoplasms; Breast Neoplasms; Carcinoma, Ehrlich Tumor; Dactinomycin; Dysgerminoma; Female; Hodgkin Disease; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Melanoma; Mice; Neoplasms; Neoplasms, Experimental; Ovarian Neoplasms; Pharmacology; Rabbits; Rectal Neoplasms; Research; Sarcoma; Sarcoma, Experimental; Tissue Culture Techniques | 1964 |
CHEMOTHERAPY OF BRAIN TUMORS. I. TRANSPLANTED MURINE EPENDYMOBLASTOMAS.
Topics: Alkylating Agents; Animals; Antineoplastic Agents; Brain Neoplasms; Cyclophosphamide; Dactinomycin; Ependymoma; Mannitol; Melphalan; Mice; Neoplasms; Neoplasms, Experimental; Neuroectodermal Tumors, Primitive; Pharmacology; Research; Toxicology | 1964 |
[RADIOAUTOGRAPHIC STUDIES ON THE UPTAKE OF H 3-ACTINOMYCIN BY MOUSE ASCITES TUMOR CELLS].
Topics: Animals; Ascites; Autoradiography; Biochemical Phenomena; Biochemistry; Carcinoma; Carcinoma, Ehrlich Tumor; Dactinomycin; DNA; DNA, Neoplasm; Mice; Necrosis; Neoplasms; Neoplasms, Experimental; Research; Tritium | 1963 |
PHARMACOLOGICAL STUDIES OF SEVERAL NEW ANTITUMOUR AGENTS.
Topics: Animals; Antimony; Antineoplastic Agents; Dactinomycin; Dogs; Haplorhini; Mice; Neoplasms, Experimental; Nitrogen Mustard Compounds; Pharmacology; Rabbits; Rats; Research; Toxicology | 1964 |
SKIN TUMORIGENESIS BY 7,12-DIMETHYLBENZ(A)ANTHRACENE: INHIBITION BY ACTINOMYCIN D.
Topics: Animals; Anthracenes; Antineoplastic Agents; Benz(a)Anthracenes; Carcinogenesis; Carcinogens; Dactinomycin; Mice; Neoplasms, Experimental; Pharmacology; Research; Skin Neoplasms; Toxicology | 1964 |
AN EXPERIMENTAL STUDY OF SIMULTANEOUS IRRADIATION AND REGIONAL CHEMOTHERAPEUTIC PERFUSION.
Topics: Chemotherapy, Cancer, Regional Perfusion; Cyclophosphamide; Dactinomycin; Mitomycin; Mitomycins; Neoplasms; Neoplasms, Experimental; Pharmacology; Rabbits; Radiotherapy Dosage; Research | 1964 |
[ON THE EFFECT OF GLUCOSE ON THE TOXIC AND THERAPEUTIC EFFECTS OF 1,6-DIBROMO-1,6-D-DIDESOXYMANNITOL IN ANIMAL EXPERIMENTS].
Topics: Aminopterin; Animal Experimentation; Animals; Antineoplastic Agents; Busulfan; Carcinoma, Ehrlich Tumor; Dactinomycin; Glucose; Mannitol; Mice; Neoplasms; Neoplasms, Experimental; Pharmacology; Research; Sarcoma 37; Sarcoma, Yoshida; Toxicology | 1964 |
INCREASED STABILITY OF TEMPLATES FOR SOME ENZYMES OF DNA SYNTHESIS IN TUMORS: DEOXYCYTIDYLATE DEAMINASE, THYMIDINE AND THYMIDYLATE KINASE.
Topics: Animals; Carcinoma, Hepatocellular; Chick Embryo; Dactinomycin; DCMP Deaminase; DNA; DNA, Neoplasm; Ligases; Liver Neoplasms; Metabolism; Neoplasms, Experimental; Nucleoside-Phosphate Kinase; Pharmacology; Phosphotransferases; Radiation Effects; Rats; Research; RNA; RNA, Messenger; Thymidine; Thymidine Kinase | 1964 |
[COMPARATIVE DATA ON THE EFFECT OF ACTINOMYCIN C AND K ON HUMAN TUMOR CELLS IN TISSUE CULTURE].
Topics: Dactinomycin; Hemangiosarcoma; Kidney Neoplasms; Melanoma; Mesonephroma; Neoplasms; Neoplasms, Experimental; Pancreatic Neoplasms; Pharmacology; Research; Stomach Neoplasms; Tissue Culture Techniques | 1964 |
THE INTRACELLULAR SITE OF FORMATION OF ENCEPHALOMYOCARDITIS VIRUS RIBONUCLEIC ACID.
Topics: Cytoplasm; Dactinomycin; Encephalomyocarditis virus; Metabolism; Neoplasms; Neoplasms, Experimental; Nucleosides; Pharmacology; Research; RNA; RNA Viruses; RNA, Neoplasm; RNA, Viral; Uracil Nucleotides; Uridine | 1965 |
STUDIES ON THE METABOLISM OF RAT-ASCITES-HEPATOMA WITH NITROGEN MUSTARD SENSITIVE AND RESISTANT STRAINS. 8. EFFECT OF CHROMOMYCIN A3 ON THE NUCLEAR RNA METABOLISM.
Topics: Anti-Bacterial Agents; Ascites; Carcinoma, Hepatocellular; Cell Nucleus; Chromomycin A3; Dactinomycin; Liver Neoplasms; Mechlorethamine; Metabolism; Neoplasms; Neoplasms, Experimental; Pharmacology; Rats; Research; RNA; RNA, Neoplasm; RNA, Nuclear | 1965 |
Inhibition of Shc/Grb2 protein-protein interaction suppresses growth of B104-1-1 tumors xenografted in nude mice.
Topics: Adaptor Proteins, Signal Transducing; Animals; Antibiotics, Antineoplastic; Cell Line, Tumor; Cell Proliferation; Dactinomycin; GRB2 Adaptor Protein; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; NIH 3T3 Cells; Protein Binding; Receptor, ErbB-2; Shc Signaling Adaptor Proteins; Signal Transduction; Src Homology 2 Domain-Containing, Transforming Protein 1; Transfection | 2005 |
Soluble TRAIL gene and actinomycin D synergistically suppressed multiple metastasis of TRAIL-resistant colon cancer in the liver.
Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Dactinomycin; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Synergism; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Humans; Liver Neoplasms; Mice; Microscopy, Fluorescence; Neoplasms, Experimental; Plasmids; Protein Synthesis Inhibitors; Solubility; TNF-Related Apoptosis-Inducing Ligand; Transfection | 2007 |
[Histochemical study of the effect of actinomycin D and Ribonuclease on the nucleic acids in Ehrlich's ascitic cells].
Topics: Animals; Carcinoma, Ehrlich Tumor; Dactinomycin; Male; Methods; Mice; Neoplasms, Experimental; Nucleic Acids; Ribonucleases | 1966 |
A model system for examining the action of anti-cancer agents at the cellular level in vivo.
Topics: Animals; Antineoplastic Agents; Azaserine; Cyclophosphamide; Dactinomycin; Fluorouracil; Hematopoiesis; Lymphoma; Mechlorethamine; Methotrexate; Mice; Models, Theoretical; Neoplasm Transplantation; Neoplasms, Experimental; Spleen; Thymidine; Tritium; Vinblastine | 1967 |
Maturation of low molecular weight RNA in tumour cells.
Topics: Carbon Isotopes; Chromatography, Gel; Dactinomycin; Methionine; Molecular Weight; Neoplasms, Experimental; RNA; Tritium; Uridine | 1967 |
Retinoids increase transglutaminase activity and inhibit ornithine decarboxylase activity in Chinese hamster ovary cells and in melanoma cells stimulated to differentiate.
Topics: Animals; Carboxy-Lyases; Cell Differentiation; Cell Line; Cricetinae; Cricetulus; Cycloheximide; Dactinomycin; Female; gamma-Glutamyltransferase; Kinetics; Melanocyte-Stimulating Hormones; Melanoma; Mice; Neoplasms, Experimental; Ornithine Decarboxylase Inhibitors; Ovary; Tretinoin; Vitamin A | 1982 |
[Intercellular information flow in the process of immunogenesis. VII. The effect of low- and high-polymer immune nuclear RNA on antibody synthesis by the cells of rat transplantable]U.
Topics: Animals; Antibodies, Neoplasm; Antibody Formation; Antibody-Producing Cells; Cell Communication; Cell Nucleus; Dactinomycin; Hemolysin Proteins; Immunization; Lymphoma, Non-Hodgkin; Macromolecular Substances; Neoplasm Transplantation; Neoplasms, Experimental; Rats; RNA; Time Factors | 1980 |
[Nucleolus segregation of tumor cells induced by actinomycin K and lycobetaine (author's transl)].
Topics: Alkaloids; Amaryllidaceae Alkaloids; Animals; Antibiotics, Antineoplastic; Cell Nucleolus; Dactinomycin; Indolizines; Mice; Neoplasms, Experimental | 1982 |
18F-5-Fluorouridine, a new probe for measuring the proliferation of tissue in vivo.
Topics: Animals; Cell Division; Dactinomycin; Female; Fluorine; Isotope Labeling; Mice; Neoplasms, Experimental; Phenylhydrazines; Radioisotopes; RNA; Uridine | 1982 |
Flow cytometric analysis of RNA content in different cell populations using pyronin Y and methyl green.
Topics: Animals; Cells, Cultured; Dactinomycin; Demecolcine; DNA; Flow Cytometry; Humans; Hydroxyurea; Interphase; Lymphocyte Activation; Lymphocytes; Methyl Green; Mice; Mitosis; Neoplasms, Experimental; Pyronine; Rats; RNA; RNA, Neoplasm; Rosaniline Dyes; Staining and Labeling; Xanthenes | 1982 |
Induction of tyrosine hydroxylase by glucocorticoids in mouse neuroblastoma cells. Enhancement of the induction by cyclic AMP.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Cells, Cultured; Cyclic AMP; Dactinomycin; Dexamethasone; Dose-Response Relationship, Drug; Enzyme Induction; Glucocorticoids; Mice; Neoplasms, Experimental; Neuroblastoma; RNA; Time Factors; Tyrosine 3-Monooxygenase | 1982 |
Effect of postoperative chemotherapy and radiotherapy, on the survival of subcutaneously implanted Furth Wilms' tumor.
Topics: Animals; Dactinomycin; Doxorubicin; Drug Therapy, Combination; Lung Neoplasms; Neoplasm Recurrence, Local; Neoplasm Transplantation; Neoplasms, Experimental; Prognosis; Rats; Transplantation, Heterologous; Vincristine; Wilms Tumor | 1981 |
Regulation of cell division and of tyrosinase in B16 melanoma cells by imidazole: a possible role for the concept of metabolite gene regulation in mammalian cells.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Catechol Oxidase; Cell Division; Cyclic AMP; Cycloheximide; Dactinomycin; Enzyme Induction; Gene Expression Regulation; Imidazoles; Melanoma; Mice; Monophenol Monooxygenase; Neoplasms, Experimental; Theophylline | 1981 |
Macromolecular synthesis is required for stimulation of estrogen synthetase activity by dibutyryl cyclic AMP plus theophylline in choriocarcinoma cell culture.
Topics: Aromatase; Bucladesine; Cells, Cultured; Choriocarcinoma; Cycloheximide; Dactinomycin; Estrogens; Female; Humans; Macromolecular Substances; NADP; NADPH-Ferrihemoprotein Reductase; Neoplasms, Experimental; Oxidoreductases; Pregnancy; Theophylline; Uterine Neoplasms | 1981 |
Expression of herpes simplex virus common surface antigens and malignancy by clonal cells of a herpes simplex virus type 2-transformed line.
Topics: Animals; Antigens, Surface; Antigens, Viral; Cell Division; Cell Transformation, Viral; Clone Cells; Cricetinae; Dactinomycin; Neoplasm Metastasis; Neoplasms, Experimental; Simplexvirus; Temperature | 1981 |
The role of phosphoproteins and newly synthesized proteins in the hormonal regulation of steroidogenesis in Leydig cells.
Topics: Animals; Cyclic AMP; Cycloheximide; Dactinomycin; Leydig Cell Tumor; Luteinizing Hormone; Male; Mice; Molecular Weight; Neoplasms, Experimental; Phosphoproteins; Protein Biosynthesis; Protein Kinases; Proteins; Steroids; Transcription, Genetic | 1983 |
Drug targeting by drug entrapment into ultrafine compartments as carriers.
Topics: Animals; Biological Transport, Active; Capsules; Colloids; Dactinomycin; Influenza Vaccines; Neoplasms, Experimental; Pharmaceutical Preparations; Subcellular Fractions | 1984 |
Anti-tumour cytotoxin produced by human monocytes: studies on its mode of action.
Topics: Adsorption; Animals; Cell Line; Cell Survival; Cytotoxins; Dactinomycin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hot Temperature; Humans; Mice; Monocytes; Neoplasms, Experimental; Oxygen Consumption; Protein Biosynthesis | 1983 |
Role of the organism in formation of carcinogenic N-nitrosodimethylamine.
Topics: Animals; Dactinomycin; Dimethylnitrosamine; Lung Neoplasms; Microsomes, Liver; Neoplasms, Experimental; Nitrosamines; Rats | 1983 |
Resistance to actinomycin D and to vincristine induced in a SEWA mouse tumor cell line with concomitant appearance of double minutes and a low molecular weight protein.
Topics: Animals; Cell Line; Chromosome Aberrations; Dactinomycin; Drug Resistance; Gene Amplification; Mice; Molecular Weight; Neoplasm Proteins; Neoplasms, Experimental; Vincristine | 1984 |
Triiodothyronine induces a transferable factor which suppresses TSH secretion in cultured mouse thyrotropic tumor cells.
Topics: Animals; Cells, Cultured; Cycloheximide; Dactinomycin; Female; In Vitro Techniques; Methotrexate; Mice; Neoplasms, Experimental; Thyroid Neoplasms; Thyrotropin; Thyrotropin-Releasing Hormone; Triiodothyronine | 1981 |
Increased uptake of actinomycin D in Ehrlich ascites tumour cells induced by daunorubicin.
Topics: Animals; Carcinoma, Ehrlich Tumor; Cell Nucleus; Cells, Cultured; Dactinomycin; Daunorubicin; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Mice; Neoplasm Transplantation; Neoplasms, Experimental | 1983 |
In vitro production of rabbit macrophage tumor cell cytotoxin.
Topics: Animals; Bone Marrow; Cell Line; Cytotoxins; Dactinomycin; Female; Fibroblasts; Glycoproteins; Growth Inhibitors; Kinetics; Lung; Macrophages; Melanoma; Molecular Weight; Monocytes; Neoplasms, Experimental; Rabbits; Time Factors; Tumor Necrosis Factor-alpha | 1983 |
Subcellular localization of LH-dependent phosphoproteins and their possible role in regulation of steroidogenesis in rat tumour Leydig cells.
Topics: Animals; Cytochalasin B; Cytosol; Dactinomycin; Leydig Cell Tumor; Luteinizing Hormone; Microsomes; Molecular Weight; Neoplasm Proteins; Neoplasms, Experimental; Phosphoproteins; Pregnenolone; Protein Biosynthesis; Rats; Subcellular Fractions; Transcription, Genetic | 1983 |
[Actinomycin D and 6-mercaptopurine-resistant Djungarian hamster cell line: karyotype, morphology, malignancy].
Topics: Animals; Cell Line; Cricetinae; Dactinomycin; Drug Resistance; Genetic Markers; Hypoxanthine Phosphoribosyltransferase; Karyotyping; Mercaptopurine; Neoplasms, Experimental; Phenotype; Transplantation, Homologous | 1981 |
Pharmacological studies comparing the mechanism of tumor-induced and activated macrophage-induced bone marrow cytolysis.
Topics: Animals; Bone Marrow Cells; Carmustine; Catalase; Cycloheximide; Cytotoxicity, Immunologic; Dactinomycin; Macrophages; Male; Mycobacterium bovis; Neoplasms, Experimental; Phagocytosis; Protease Inhibitors; Rats; Superoxide Dismutase | 1980 |
[Study for the experimental chemotherapy and clinical application (author's transl)].
Topics: Adult; Animals; Antineoplastic Agents; Choriocarcinoma; Cyclophosphamide; Dactinomycin; Drug Therapy, Combination; Female; Humans; Methotrexate; Mice; Mice, Nude; Neoplasms, Experimental; Pregnancy; Uterine Neoplasms; Vincristine | 1982 |
Prevention of intravascular metastases of B16 murine melanoma: adjuvant chemotherapy with actinomycin D.
Topics: Animals; Cell Line; Dactinomycin; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Evaluation, Preclinical; Lung Neoplasms; Melanoma; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Neoplasms, Experimental; Neoplastic Cells, Circulating | 1982 |
Multiple drug plus radiation enhancement during 4MV irradiation of HEp 2 cells.
Topics: Carcinoma, Squamous Cell; Cell Line; Dactinomycin; Dose-Response Relationship, Drug; Doxorubicin; Drug Therapy, Combination; Humans; Laryngeal Neoplasms; Neoplasms, Experimental; Radiotherapy Dosage | 1982 |
[Experimental chemotherapy with drug-resistant choriocarcinoma transplanted to nude mice (author's transl)].
Topics: Animals; Antineoplastic Agents; Choriocarcinoma; Cyclophosphamide; Dactinomycin; Drug Resistance; Female; Humans; Methotrexate; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Pregnancy; Uterine Neoplasms; Vincristine | 1981 |
Therapy for Nb rat tumor transplanted in athymic mice.
Topics: Adenocarcinoma; Androgens; Animals; Carmustine; Dactinomycin; Male; Mice; Mice, Nude; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms, Experimental; Prostatic Neoplasms; Rats; Transplantation, Heterologous | 1981 |
Liposome-cell interactions. A study of the interactions of liposomes containing entrapped anti-cancer drugs with the EMT6, S49 and AE1 (transport-deficient) cell lines.
Topics: Animals; Biological Transport; Cell Line; Cytarabine; Dactinomycin; Female; Liposomes; Lymphoma; Mammary Neoplasms, Experimental; Methotrexate; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Phospholipids; Ribonucleosides; Tubercidin | 1981 |
Failure of actinomycin D entrapped in liposomes to prolong survival in renal cell adenocarcinoma-bearing mice.
Topics: Adenocarcinoma; Animals; Cells, Cultured; Dactinomycin; Graft Survival; Kidney Neoplasms; Liposomes; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Neoplasms, Experimental; Transplantation, Homologous | 1981 |
[Nucleic acid synthesis in the cells of some ascites tumors induced by change in ionic homeostasis].
Topics: Animals; Carcinoma, Ehrlich Tumor; Dactinomycin; DNA Replication; DNA, Neoplasm; Homeostasis; Kinetics; Mice; Neoplasms, Experimental; Osmolar Concentration; Ouabain; Potassium; Rats; RNA, Neoplasm; Sodium | 1981 |
Development of resistance to vincristine in a childhood rhabdomyosarcoma growing in immune-deprived mice.
Topics: Animals; Child; Dactinomycin; Doxorubicin; Drug Resistance; Humans; Immunosuppression Therapy; Karyotyping; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Neoplasms, Experimental; Rhabdomyosarcoma; Transplantation, Heterologous; Vinblastine; Vincristine | 1981 |
Direct determination of the influence of the cell cycle on the survival of tumor cells exposed to cytotoxic antibodies.
Topics: Animals; Antibodies, Neoplasm; Cell Cycle; Cell Line; Cell Survival; Dactinomycin; Immunotherapy; Melphalan; Mice; Multiple Myeloma; Neoplasms, Experimental | 1980 |
Cross resistance between actinomycin-D, adriamycin and vincristine in a murine solid tumour in vivo.
Topics: Animals; Cells, Cultured; Dactinomycin; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance; Mice; Neoplasms, Experimental; Sarcoma, Experimental; Vincristine | 1980 |
Evaluation of nonhormonal cytotoxic chemotherapy in the Nb rat prostate adenocarcinoma: autonomous tumor (18-Pr and 13-Pr).
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cyclophosphamide; Dactinomycin; Doxorubicin; Drug Evaluation, Preclinical; Fluorouracil; Male; Methotrexate; Neoplasm Transplantation; Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Rats; Time Factors | 1980 |
Tumor cell lipid composition and sensitivity to humoral immune killing. II. Influence of plasma membrane and intracellular lipid and fatty acid content.
Topics: Animals; Cell Membrane; Complement System Proteins; Cytotoxicity, Immunologic; Dactinomycin; Doxorubicin; Endoplasmic Reticulum; Fatty Acids; Guinea Pigs; Humans; Hydrocortisone; Lipids; Neoplasms, Experimental; Ribonucleoproteins; Subcellular Fractions | 1980 |
Interleukin-3 mRNA stabilization by a trans-acting mechanism in autocrine tumors lacking interleukin-3 gene rearrangements.
Topics: Animals; Base Sequence; Cell Line, Transformed; Cell Transformation, Neoplastic; Dactinomycin; DNA Primers; DNA Replication; Gene Rearrangement; Genes, ras; Interleukin-3; Kinetics; Mast Cells; Mice; Mice, Inbred DBA; Molecular Sequence Data; Neoplasms, Experimental; Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Thymidine; Transcription, Genetic; Transcriptional Activation; Transfection | 1995 |
Potentiation of the anti-tumor effect of actinomycin D by tumor necrosis factor alpha in mice: correlation between in vitro and in vivo results.
Topics: Animals; Antibiotics, Antineoplastic; Cell Line; Dactinomycin; Drug Synergism; Leukemia L1210; Lung Neoplasms; Melanoma, Experimental; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasms, Experimental; Sarcoma, Experimental; Time Factors; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1996 |
Insulin-mediated alterations in S-adenosylmethionine decarboxylase expression in H-ras transformed cells of varying degrees of malignancy.
Topics: Adenosylmethionine Decarboxylase; Animals; Blotting, Northern; Cell Line, Transformed; Cycloheximide; Dactinomycin; Fibrosarcoma; Genes, ras; Insulin; Mice; Neoplasms, Experimental; Phenotype; Protein Synthesis Inhibitors; RNA Processing, Post-Transcriptional; RNA, Messenger; Time Factors; Transcription, Genetic | 2000 |
Relationship of adhesiveness of cells in culture with specific enzyme activity.
Topics: Animals; Cell Adhesion; Cell Cycle; Cells, Cultured; Dactinomycin; Glutamate-Ammonia Ligase; Hydrocortisone; Mice; Neoplasm Proteins; Neoplasms, Experimental; Teratoma | 1979 |
[Correlation of in vitro testing and therapeutical results in animal transplanted tumors after cytostatic treatment].
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Bleomycin; Carcinoma 256, Walker; Cricetinae; Dactinomycin; Doxorubicin; In Vitro Techniques; Male; Melanoma; Neoplasm Transplantation; Neoplasms, Experimental; Plasmacytoma; Podophyllin; Rats; Thymidine; Triaziquone; Uridine | 1975 |
Effects of antineoplastic agents on wound healing in mice.
Topics: Animals; Antineoplastic Agents; Bleomycin; Carmustine; Cyclophosphamide; Dactinomycin; Doxorubicin; Fluorouracil; Injections, Intraperitoneal; Male; Melanoma; Methotrexate; Mice; Neoplasms, Experimental; Vincristine; Wound Healing | 1975 |
Alteration of cell-surface antigenicity of the mouse plasmacytoma. I. Immunologic characterization of surface antigens masked during successive transplantations.
Topics: Animals; Antigens, Neoplasm; B-Lymphocytes; Bone Marrow; Bone Marrow Cells; Cell Membrane; Complement System Proteins; Dactinomycin; Epitopes; Histocompatibility Antigens; Immunoglobulin A; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Neoplasms, Experimental; Peptide Hydrolases; Plasmacytoma; Pronase; Puromycin; Spleen; Transplantation, Homologous | 1975 |
Enhancing effect by metabolic inhibitors on the killing of tumor cells by antibody and complement.
Topics: Animals; Antibodies, Neoplasm; Antigen-Antibody Reactions; Antineoplastic Agents; Azacitidine; Carcinoma, Hepatocellular; Cells, Cultured; Complement System Proteins; Cyclophosphamide; Cytarabine; Dactinomycin; Doxorubicin; Fluorouracil; Guinea Pigs; Hydroxyurea; Liver Neoplasms; Mercaptopurine; Methotrexate; Mitomycins; Neoplasms, Experimental; Puromycin; Vincristine | 1975 |
Effect of metabolic inhibitors on the ability of tumor cells to express antigen and bind complement components C4 and C3.
Topics: Animals; Antigen-Antibody Reactions; Antigens, Neoplasm; Antineoplastic Agents; Azacitidine; Binding Sites, Antibody; Carcinoma, Hepatocellular; Cell Membrane; Cells, Cultured; Complement C3; Complement C4; Complement System Proteins; Dactinomycin; Doxorubicin; Guinea Pigs; Liver Neoplasms; Methotrexate; Neoplasms, Experimental; Puromycin | 1975 |
Effects of adriamycin on the reverse transcriptase and the production of murine leukemia virus.
Topics: Animals; Cell Division; Cell Line; Dactinomycin; Doxorubicin; Drug Resistance; Leukemia Virus, Murine; Mice; Neoplasms, Experimental; Reverse Transcriptase Inhibitors; Virus Replication | 1976 |
Effect of dibutyryl cyclic adenosine 5'-monophosphate on protein synthesis in L5178Y cells after hyperthermia.
Topics: Bucladesine; Cell Line; Dactinomycin; Hyperthermia, Induced; Kinetics; Leucine; Lymphoma; Neoplasm Proteins; Neoplasms, Experimental; RNA, Neoplasm; Sodium Fluoride; Theophylline | 1977 |
Effects of adriamycin and actinomycin D on nucleolar morphology: A simple biologic assay.
Topics: Animals; Carcinoma, Hepatocellular; Cell Nucleolus; Dactinomycin; Doxorubicin; Liver Neoplasms; Male; Neoplasms, Experimental; Rats; Ribonucleoproteins; Staining and Labeling; Tolonium Chloride | 1977 |
[Biological properties of the modified actinomycins synthesized by the aurantin producer].
Topics: Amino Acids; Animals; Carcinoma, Hepatocellular; Dactinomycin; DNA, Bacterial; Escherichia coli; Flavonoids; Liver Neoplasms; Male; Mice; Mice, Inbred C3H; Microbial Sensitivity Tests; Mitosis; Neoplasms, Experimental; RNA, Neoplasm; Streptomyces | 1978 |
[Effect of actinomycin D, carminomycin and bleomycin and their joint use with serotonin and zymosan on the functional state of the peritoneal macrophages].
Topics: Animals; Antibiotics, Antineoplastic; Bleomycin; Carubicin; Dactinomycin; Drug Combinations; Female; Macrophages; Mice; Mice, Inbred CBA; Neoplasm Transplantation; Neoplasms, Experimental; Peritoneal Cavity; Phagocytosis; Serotonin; Time Factors; Uterine Cervical Neoplasms; Zymosan | 1978 |
Selective enzyme induction in a nerve growth factor-responsive pheochromocytoma cell line (PC 12).
Topics: Adrenal Gland Neoplasms; Animals; Cell Line; Choline O-Acetyltransferase; Dactinomycin; Dexamethasone; Enzyme Induction; Neoplasms, Experimental; Nerve Growth Factors; Pheochromocytoma; Rats; Tyrosine 3-Monooxygenase | 1978 |
Lactic dehydrogenase activity in degenerative neoplastic glial cells after actinomycin application in vitro.
Topics: Cells, Cultured; Dactinomycin; Glioblastoma; Humans; L-Lactate Dehydrogenase; Neoplasms, Experimental; Nerve Degeneration | 1979 |
Sensitivity tests of tumors to cytostatic agents. I. Comparative investigations on transplanted tumors in vivo and in vitro.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carcinoma 256, Walker; Cell Division; Cricetinae; Dactinomycin; Daunorubicin; Dose-Response Relationship, Drug; Doxorubicin; Fluorouracil; In Vitro Techniques; Melanoma; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Neoplasms, Experimental; Plasmacytoma; Procarbazine; Rats; Rats, Inbred ACI; Sarcoma 180; Thymidine; Triaziquone; Uridine | 1975 |
The carcinogenic properties of some of the principal drugs used in clinical cancer chemotherapy.
Topics: Animals; Antineoplastic Agents; Carcinogens; Chlorambucil; Cyclophosphamide; Dacarbazine; Dactinomycin; Diethylnitrosamine; Female; Humans; Male; Melphalan; Mice; Mitobronitol; Mitolactol; Mitomycins; Neoplasms, Experimental; Nitrogen Mustard Compounds; Picolinic Acids; Procarbazine; Rats; Streptozocin; Uracil Mustard | 1975 |
Effect of actinomycin D and neoarsphenamine on tumor control and skin tolerance in the rat.
Topics: Animals; Arsenicals; Dactinomycin; Neoplasms, Experimental; Radiation-Sensitizing Agents; Rats; Rhabdomyosarcoma; Skin; Time Factors | 1978 |
Functional differences in protein synthesis between rat liver tRNA and tRNA from Novikoff hepatoma.
Topics: Animals; Carcinoma, Hepatocellular; Chickens; Dactinomycin; Estradiol; Female; Liver; Liver Neoplasms; Male; Neoplasms, Experimental; Ovalbumin; Oviducts; Rats; Ribonucleases; RNA, Transfer | 1975 |
Nuclear DNA of mouse hepatoma studied by 3-H-actinomycin D binding.
Topics: Animals; Binding Sites; Carcinoma, Hepatocellular; Cell Nucleus; Dactinomycin; DNA, Neoplasm; Heterochromatin; Liver; Liver Neoplasms; Mice; Neoplasms, Experimental; Tritium | 1975 |
Cytoplasmic DNA of hepatoma tumor cells studied by 3H-actinomycin D binding.
Topics: Animals; Autoradiography; Binding Sites; Carcinoma, Hepatocellular; Cytoplasm; Dactinomycin; DNA, Mitochondrial; DNA, Neoplasm; Liver; Liver Neoplasms; Mice; Neoplasms, Experimental; Tritium | 1975 |
Effects of cyclic adenosine monophosphate, dexamethasone and insulin on phosphoenolpyruvate carboxykinase synthesis in Reuber H-35 hepatoma cells.
Topics: Animals; Bucladesine; Carcinoma, Hepatocellular; Cells, Cultured; Dactinomycin; Deoxyadenosines; Dexamethasone; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Glucagon; Glucose; Insulin; Kinetics; Leucine; Liver Neoplasms; Neoplasms, Experimental; Phosphoenolpyruvate Carboxykinase (GTP); Rats; RNA; RNA, Messenger; Theophylline | 1975 |
Requirement for protein synthesis in the regulation of protein breakdown in cultured hepatoma cells.
Topics: Carcinoma, Hepatocellular; Cell Line; Cycloheximide; Dactinomycin; Insulin; Liver Neoplasms; Neoplasm Proteins; Neoplasms, Experimental; Pactamycin; Protein Biosynthesis; Puromycin; RNA, Transfer | 1975 |
The effects of chemotherapy on the Wistar-Furth Wilms' Tumor.
Topics: Animals; Body Weight; Dactinomycin; Dose-Response Relationship, Drug; Models, Biological; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms, Experimental; Rats; Rats, Inbred WF; Vincristine; Wilms Tumor | 1975 |
A murine Wilms' tumor as a model for chemotherapy and radiotherapy.
Topics: Animals; Cyclophosphamide; Dactinomycin; Doxorubicin; Drug Therapy, Combination; Leucovorin; Methotrexate; Neoplasms, Experimental; Rats; Vincristine; Wilms Tumor | 1976 |
Regression of established tumors and induction of tumor immunity by intratumor chemotherapy.
Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Carmustine; Dacarbazine; Dactinomycin; Doxorubicin; Drug Therapy, Combination; Fluorouracil; Graft Rejection; Guinea Pigs; Injections; Injections, Intraperitoneal; Liver Neoplasms; Melphalan; Mercaptopurine; Methotrexate; Mitomycins; Neoplasm Transplantation; Neoplasms, Experimental | 1976 |
Biology of SV40 transplantation antigen (TrAg). I. Demonstration of SV40 TrAg on glutaraldehyde-fixed SV40-infected African green monkey kidney cells.
Topics: Animals; Antigens, Viral; Cell Line; Cytarabine; Dactinomycin; DNA, Viral; Glutaral; Haplorhini; Histocompatibility Antigens; Immunity; Mice; Mice, Inbred BALB C; Mutation; Neoplasm Transplantation; Neoplasms, Experimental; Simian virus 40; Temperature; Virus Replication | 1976 |
The appearance of an ornithine decarboxylase inhibitory protein upon the addition of putrescine to cell cultures.
Topics: Carboxy-Lyases; Carcinoma, Hepatocellular; Cell Line; Culture Media; Cycloheximide; Dactinomycin; Kinetics; Liver Neoplasms; Neoplasm Proteins; Neoplasms, Experimental; Ornithine Decarboxylase Inhibitors; Protein Biosynthesis; Putrescine | 1976 |
Binding of cyclic nucleotides with proteins in malignant and adenosine cyclic 3':5'-monophosphate-induced "differentiated" neuroblastoma cells in culture.
Topics: Adenosine Monophosphate; Animals; Cell Differentiation; Cells, Cultured; Cyclic AMP; Cyclic GMP; Cycloheximide; Dactinomycin; L Cells; Neoplasm Proteins; Neoplasms, Experimental; Neuroblastoma; Neuroglia; Nucleotides, Cyclic; Protein Binding; Rats | 1976 |
Stimulation of ornithine decarboxylase synthesis and its control by polyamines in regenerating rat liver and cultured rat hepatoma cells.
Topics: Animals; Bucladesine; Carboxy-Lyases; Carcinoma, Hepatocellular; Cell Line; Cycloheximide; Dactinomycin; Drug Stability; Enzyme Induction; Hot Temperature; Kinetics; Liver; Liver Neoplasms; Liver Regeneration; Neoplasms, Experimental; Ornithine Decarboxylase; Polyamines; Precipitin Tests; Rats; Spermidine; Spermine; Time Factors | 1976 |
The regulation of ornithine aminotransferase synthesis by glucagon in the rat.
Topics: Animals; Carcinoma, Hepatocellular; Dactinomycin; Dose-Response Relationship, Drug; Enzyme Induction; Glucagon; Immunodiffusion; Kidney; Liver Neoplasms; Male; Mitochondria; Mitochondria, Liver; Molecular Weight; Neoplasms, Experimental; Organ Specificity; Ornithine-Oxo-Acid Transaminase; Precipitin Tests; Rats; Transaminases | 1976 |
The induction of tumour cell adhesiveness and intercellular junctions by a glycoprotein of rat ascites hepatoma cell surface.
Topics: Animals; Carcinoma, Hepatocellular; Cell Adhesion; Colony-Stimulating Factors; Dactinomycin; Desmosomes; Glycoproteins; In Vitro Techniques; Intercellular Junctions; Liver Neoplasms; Microscopy, Electron; Neoplasm Proteins; Neoplasms, Experimental; Rats; Skin Neoplasms; Time Factors | 1976 |
Thymidylate synthetase activity in the Novikoff hepatoma.
Topics: Animals; Carcinoma, Hepatocellular; Cycloheximide; Dactinomycin; Folic Acid; Liver Neoplasms; Male; Methotrexate; Methyltransferases; Neoplasms, Experimental; Puromycin; Rats; Tetrahydrofolates; Thymidylate Synthase | 1976 |
Nucleic acids from subcellular fractions of N-nitrosodiethylamine-induced hepatoma in mice.
Topics: Acridines; Animals; Carcinoma, Hepatocellular; Cell Nucleus; Dactinomycin; Diethylnitrosamine; DNA, Neoplasm; Genes; Liver Neoplasms; Male; Mice; Mice, Inbred C3H; Mitochondria, Liver; Mitosis; Neoplasms, Experimental; RNA, Messenger; RNA, Neoplasm | 1976 |
Metabolic regulation and relationship of endogenous protein kinase activity and steroidogenesis in isolated adrenocortical carcinoma cells of the rat.
Topics: Adenylyl Cyclases; Adrenal Cortex Hormones; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocorticotropic Hormone; Animals; Corticosterone; Cyclic AMP; Cyclic GMP; Cycloheximide; Dactinomycin; Enzyme Activation; In Vitro Techniques; Neoplasms, Experimental; Oxidative Phosphorylation; Protein Kinases; Rats | 1977 |
Platelet aggregating material in mouse tumor cells. Removal and regeneration.
Topics: Animals; Cell Line; Cell-Free System; Cycloheximide; Dactinomycin; Depression, Chemical; Embryo, Mammalian; Fibroblasts; Lymphocytes; Macrophages; Mice; Microbial Collagenase; Neoplasms, Experimental; Platelet Aggregation; Protein Biosynthesis; Puromycin; Rats; Spleen; Trypsin | 1977 |
Translational regulatory mechanisms in neoplasia in vivo.
Topics: Animals; Carcinoma, Hepatocellular; Dactinomycin; Enzyme Induction; Genes; Glucose; Liver Neoplasms; Neoplasms, Experimental; Protein Biosynthesis; Rats; RNA, Messenger; Tryptophan Oxygenase | 1976 |
Effect of inhibiting DNA, RNA, and protein synthesis of tumor cells on their susceptibility to killing by antibody and complement.
Topics: Antibodies; Carcinoma, Hepatocellular; Cell Line; Complement System Proteins; Cytotoxicity Tests, Immunologic; Dactinomycin; DNA, Neoplasm; Doxorubicin; Hot Temperature; Liver Neoplasms; Neoplasm Proteins; Neoplasms, Experimental; Puromycin; Radiation Effects; RNA, Neoplasm; Time Factors | 1977 |
Effect of alpha-methyl ornithine on ornithine decarboxylase activity of rat hepatoma cells in culture.
Topics: Animals; Carboxy-Lyases; Carcinoma, Hepatocellular; Cell Division; Cells, Cultured; Cycloheximide; Dactinomycin; Liver Neoplasms; Neoplasms, Experimental; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Rats; RNA, Messenger | 1977 |
Collagenase and neutral protease activities in cultures of rabbit VX-2 carcinoma.
Topics: Animals; Cells, Cultured; Chromatography, Gel; Cycloheximide; Dactinomycin; Kinetics; Microbial Collagenase; Neoplasms, Experimental; Peptide Hydrolases; Protease Inhibitors; Rabbits; Viscosity | 1977 |
[Characteristics of mRNA metabolism in tumor cells. The hypothesis of the uncoupling of the processes of polyribosome formation and functioning in the tumor cell].
Topics: Animals; Biological Transport; Carcinoma, Hepatocellular; Cell Membrane; Cell Nucleus; Cycloheximide; Cytoplasm; Dactinomycin; Free Radicals; Liver Neoplasms; Neoplasms, Experimental; Phenylalanine; Polyribosomes; Rats; RNA, Messenger; RNA, Neoplasm; Uridine | 1977 |
Marked stimulation of lymphocyte-mediated attack on tumor cells by target-directed liposomes containing immune RNA.
Topics: Animals; Antilymphocyte Serum; Carcinoma, Hepatocellular; Cytotoxicity, Immunologic; Dactinomycin; Guinea Pigs; In Vitro Techniques; Liposomes; Liver Neoplasms; Lymphocytes; Neoplasms, Experimental; RNA | 1978 |
Turnover of messenger RNA in transplantable hepatomas and host liver of rats.
Topics: Animals; Carcinoma, Hepatocellular; Dactinomycin; Female; Liver; Liver Neoplasms; Neoplasm Transplantation; Neoplasms, Experimental; Orotic Acid; Poly A; Polyribosomes; Rats; Rats, Inbred BUF; Ribonucleases; RNA, Messenger; RNA, Neoplasm; Transplantation, Isogeneic | 1978 |
Co-cultivation of tumorigenic mouse melanoma cells with cells of a non-tumorigenic subclone inhibits plasminogen activator expression by the melanoma cells.
Topics: Animals; Bromodeoxyuridine; Cell Division; Cell Fusion; Clone Cells; Dactinomycin; Melanoma; Mice; Mitomycins; Neoplasms, Experimental; Plasminogen Activators; Retroviridae | 1978 |
Tumor cell killing by macrophages activated in vitro with lymphocyte mediators. II. Inhibition by inhibitors of protein synthesis.
Topics: Animals; Antimetabolites; Carcinoma, Hepatocellular; Cytotoxicity, Immunologic; Dactinomycin; Depression, Chemical; Guinea Pigs; Liver Neoplasms; Macrophages; Mitomycins; Neoplasms, Experimental; Pactamycin; Puromycin; Puromycin Aminonucleoside | 1978 |
Influence of chemotherapeutic agents on chorionic gonadotropin-alpha subunit secretion in a human lung cancer cell line (ChaGo): discordance of cytotoxic and secretory effects.
Topics: Antineoplastic Agents; Cell Division; Cell Line; Chorionic Gonadotropin; Dactinomycin; Hormones, Ectopic; Humans; Lung Neoplasms; Mechlorethamine; Methotrexate; Neoplasm Proteins; Neoplasms, Experimental; Procarbazine; Vincristine | 1978 |
Induction of differentiation of Rauscher virus-induced mouse myeloid leukemia cells with a factor(s) in ascitic fluid and inhibitors of nucleic acid and protein syntheses.
Topics: Animals; Antimetabolites, Antineoplastic; Ascitic Fluid; Cell Differentiation; Cell Movement; Dactinomycin; Leukemia, Experimental; Mice; Neoplasms, Experimental; Nucleic Acids; Protein Biosynthesis; Rats; Rauscher Virus | 1979 |
Ganglioside composition of malignant and actinomycin D-resistant nonmalignant Chinese hamster cells.
Topics: Animals; Cells, Cultured; Cricetinae; Cricetulus; Dactinomycin; Drug Resistance; Gangliosides; Neoplasms, Experimental | 1979 |
Murine primitive neuroectodermal tumor: nucleolar isolation and RNA polymerase inhibition.
Topics: Amanitins; Animals; Cell Fractionation; Cell Nucleolus; Cell Nucleus; Dactinomycin; DNA-Directed RNA Polymerases; Doxorubicin; Ependymoma; Magnesium; Mice; Neoplasms, Experimental; RNA Polymerase I | 1979 |
Inhibition of DNA synthesis in Harding-Passey melanoma cells by prostaglandins A1 and A2: comparison with chemotherapeutic agents.
Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Dactinomycin; DNA Replication; DNA, Neoplasm; Doxorubicin; Fluorouracil; Hydroxyurea; Kinetics; Melanoma; Mice; Neoplasms, Experimental; Prostaglandins A | 1979 |
Evaluation of whole-body hyperthermia as an adjunct to chemotherapy in murine tumors.
Topics: Animals; Antineoplastic Agents; Body Temperature; Cyclophosphamide; Dactinomycin; Doxorubicin; Female; Hyperthermia, Induced; Lomustine; Male; Methods; Mice; Neoplasms, Experimental; Semustine; Vincristine | 1979 |
Effect of temperature on protein and immunoglobulin synthesis and secretion in two mouse myeloma cell lines.
Topics: Animals; Cell Line; Dactinomycin; Electrophoresis, Polyacrylamide Gel; Immunoglobulin G; Mice; Multiple Myeloma; Myeloma Proteins; Neoplasms, Experimental; Protein Biosynthesis; Ribosomes; Sodium Chloride; Temperature | 1979 |
Prostate adenocarcinoma model: Nb rat chemotherapy.
Topics: Adenocarcinoma; Animals; Castration; Cyclophosphamide; Dactinomycin; Disease Models, Animal; Doxorubicin; Fluorouracil; Male; Neoplasms, Experimental; Prostatic Neoplasms; Rats | 1979 |
Chemotherapy of human choriocarcinoma transplanted to nude mice.
Topics: Adult; Animals; Antineoplastic Agents; Choriocarcinoma; Chorionic Gonadotropin; Dactinomycin; Drug Therapy, Combination; Female; Humans; Methotrexate; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms, Experimental; Pregnancy; Transplantation, Heterologous; Vinblastine | 1978 |
Fibrinolysis induced by rat glioma cells. A mitosis-triggered process?
Topics: Animals; Astrocytoma; Cell Line; Dactinomycin; Fibrin Fibrinogen Degradation Products; Fibrinolysis; Glioma; Hydroxyurea; Mitotic Index; Neoplasms, Experimental; Plasminogen Activators; Rats; S100 Proteins | 1978 |
Relationship between plasma levels of human chorionic gonadotropin and tumor growth during chemotherapy for human choriocarcinoma maintained in the hamster cheek pouch.
Topics: Animals; Choriocarcinoma; Chorionic Gonadotropin; Cricetinae; Dactinomycin; Female; Humans; Mesocricetus; Methotrexate; Neoplasm Transplantation; Neoplasms, Experimental; Pregnancy; Transplantation, Heterologous; Uterine Neoplasms | 1978 |
Correlation between characteristics of transformation and malignancy of intra and interspecific somatic hybrid cells.
Topics: Agglutination; Animals; Cell Line; Cell Transformation, Neoplastic; Concanavalin A; Cricetinae; Culture Media; Dactinomycin; Drug Resistance; Genes; Humans; Hybrid Cells; Mice; Neoplasm Transplantation; Neoplasms, Experimental | 1978 |
Tumor cell cytostasis by macrophages and antibody in vitro. II. Isolation and characterization of suppressed cells.
Topics: Antibodies; Cell Separation; Cell Transformation, Neoplastic; Dactinomycin; Glucose; Immunosuppression Therapy; Leucine; Macrophages; Neoplasms, Experimental; Uridine | 1978 |
Further experience with chemotherapy in the Dunning prostatic adenocarcinoma.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Asparaginase; Cyclophosphamide; Dactinomycin; Doxorubicin; Drug Therapy, Combination; Fluorouracil; Hybridization, Genetic; Hydroxyurea; Lomustine; Male; Methotrexate; Neoplasms, Experimental; Platinum; Prostatic Neoplasms; Rats | 1978 |
Properties and synthesis of multiple components in native small ribosomal subunits of mouse ascites tumor cells.
Topics: Animals; Cell Fractionation; Centrifugation, Density Gradient; Dactinomycin; Edetic Acid; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Nucleoproteins; Ribosomes; RNA, Neoplasm; Uridine | 1975 |
[Combination chemotherapy of tumors (an experimental study)].
Topics: Animals; Antineoplastic Agents; Busulfan; Carcinoma, Ehrlich Tumor; Chlorambucil; Cyclophosphamide; Dactinomycin; Drug Synergism; Drug Therapy, Combination; Mice; Neoplasms, Experimental; Streptonigrin; Thiotepa; Time Factors; Vinblastine | 1975 |
Melanocyte-stimulating hormone promotes activation of pre-existing tyrosinase molecules in Cloudman S91 melanoma cells.
Topics: Catechol Oxidase; Cell Line; Cycloheximide; Dactinomycin; Enzyme Activation; Melanocyte-Stimulating Hormones; Melanoma; Neoplasm Proteins; Neoplasms, Experimental; RNA, Neoplasm | 1975 |
Synthesis and antitumor activity of 2-deamino- and N2-(gamma-hydroxypropyl)actinomycin D.
Topics: 1-Propanol; Animals; Antineoplastic Agents; Bacillus subtilis; Dactinomycin; Deamination; Leukemia L1210; Leukemia, Experimental; Male; Melanoma; Mice; Microbial Sensitivity Tests; Neoplasms, Experimental; Sarcina; Spectrophotometry; Staphylococcus aureus | 1975 |
Tests for tumor induction by antitumor agents.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Benz(a)Anthracenes; Carcinogens; Dactinomycin; Daunorubicin; DNA; Female; Hydroxyurea; Mammary Neoplasms, Experimental; Mice; Mice, Inbred A; Neoplasms, Experimental; Rats | 1975 |
The inhibition of thymidine kinase in glial tumor cells by an amino sugar, D-glucosamine.
Topics: Amino Acids; Cells, Cultured; Cycloheximide; Dactinomycin; Glioma; Glucosamine; Isoenzymes; Kinetics; Neoplasms, Experimental; Thymidine Kinase; Uridine | 1977 |
Hamster apigmented melanoma as a model for screening of potential antineoplastic drugs.
Topics: Animals; Antineoplastic Agents; Cricetinae; Cyclophosphamide; Dactinomycin; Drug Evaluation, Preclinical; Melanoma; Mercaptopurine; Neoplasms, Experimental; Skin Neoplasms; Vinblastine | 1977 |
Bifunctional intercalators: relationship of antitumor activity of diacridines to the cell membrane.
Topics: Acridines; Biological Transport; Cell Aggregation; Cell Line; Cell Membrane; Dactinomycin; DNA; Neoplasms, Experimental; RNA; Structure-Activity Relationship | 1977 |
Use of lipid vesicles as carriers to introduce actinomycin D into resistant tumor cells.
Topics: Animals; Cell Division; Cell Line; Cell Membrane; Dactinomycin; Dose-Response Relationship, Drug; Drug Resistance; Lipids; Neoplasms, Experimental; Pharmaceutical Vehicles; RNA, Neoplasm | 1976 |
[Synthesis of messenger-like RNA in plasma cels producing different clases of immunoglobulins].
Topics: Animals; Dactinomycin; Female; Immunoglobulin A; Immunoglobulin G; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Neoplasms, Experimental; Plasmacytoma; Poly A; Rats; RNA, Messenger; RNA, Neoplasm | 1976 |
Hormone responsive human breast cancer in long-term tissue culture: effect of insulin.
Topics: Breast Neoplasms; Cell Division; Cell Line; Culture Techniques; Dactinomycin; Dexamethasone; DNA, Neoplasm; Glucose; Humans; Insulin; Neoplasm Proteins; Neoplasms, Experimental; RNA, Neoplasm | 1976 |
[Suppression of postradiation regeneration as one of possible ways of increasing tumor cell destruction].
Topics: Animals; Cytarabine; Dactinomycin; DNA Repair; DNA Replication; DNA, Neoplasm; Neoplasms, Experimental; Radiation Effects | 1975 |
Correlation between resistance to actinomycin D, karyology, agglutination by concanavalin A and tumorigenicity in Chinese hamster hybrid cells.
Topics: Agglutination Tests; Animals; Cell Transformation, Neoplastic; Chromosomes; Clone Cells; Concanavalin A; Cricetinae; Dactinomycin; Hybrid Cells; Hybridization, Genetic; Immunity, Cellular; Karyotyping; Neoplasm Transplantation; Neoplasms, Experimental | 1975 |
Sequential irreversible, actinomycin D-sensitive, and cycloheximide-sensitive steps prior to cortisol inhibition of uridine utilization by P1798 tumor lymphocytes.
Topics: Animals; Cycloheximide; Dactinomycin; Depression, Chemical; Female; Hydrocortisone; Hydroxyurea; Lymphocytes; Mice; Mice, Inbred BALB C; Neoplasm Proteins; Neoplasm Transplantation; Neoplasms, Experimental; Phenylalanine; Protein Biosynthesis; RNA; RNA, Neoplasm; Thymidine; Time Factors; Transcription, Genetic; Uridine | 1975 |
Treatment of tumour bearing mice with liponsome-entrapped actinomycin D prolongs their survival.
Topics: Animals; Autoradiography; Dactinomycin; Liposomes; Lymphoma; Mice; Mice, Inbred AKR; Mitosis; Neoplasms, Experimental; Staphylococcus; Time Factors | 1975 |
Changes in sensitivity to cytotoxic agents occurring during the life history of monolayer cultures of a mouse tumour cell line.
Topics: Alkylating Agents; Animals; Antibiotics, Antineoplastic; Carmustine; Cell Division; Cell Line; Cell Survival; Dactinomycin; Dose-Response Relationship, Drug; Doxorubicin; Lomustine; Mechlorethamine; Mice; Neoplasms, Experimental | 1975 |
Antineoplastic activity of cannabinoids.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Bone Marrow; Bone Marrow Cells; Cannabidiol; Cannabis; Dactinomycin; Dose-Response Relationship, Drug; Dronabinol; Friend murine leukemia virus; In Vitro Techniques; Leukemia L1210; Lung Neoplasms; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasms, Experimental; Phytotherapy; Splenomegaly; Thymidine; Uridine | 1975 |
Membrane-mediated drug resistance and phenotypic reversion to normal growth behavior of Chinese hamster cells.
Topics: Animals; Cell Line; Cell Membrane Permeability; Cell Transformation, Neoplastic; Cricetinae; Dactinomycin; Daunorubicin; Drug Resistance; Methotrexate; Neoplasms, Experimental; Vinca Alkaloids; Vincristine | 1975 |
Sesquiterpene lactones XVII. Cytostatic and pharmacological activity.
Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Dactinomycin; Leukemia L1210; Methotrexate; Mice; Mice, Inbred A; Mice, Inbred BALB C; Neoplasm Transplantation; Neoplasms, Experimental; Sarcoma 180; Sesquiterpenes; Transplantation, Homologous | 1975 |
Potentiation of actinomycin D or adriamycin antitumor activity with DNA.
Topics: Animals; Dactinomycin; Daunorubicin; DNA; Doxorubicin; Drug Synergism; Leukemia L1210; Leukemia, Experimental; Leukemia, Lymphoid; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Neoplasms, Experimental | 1976 |
Tumorigenicity in vivo and induction of malignant transformation and mutagenesis in cell cultures by adriamycin and daunomycin.
Topics: Adenocarcinoma; Animals; Cell Transformation, Neoplastic; Cells, Cultured; Clone Cells; Dactinomycin; Daunorubicin; Doxorubicin; Female; Kidney Neoplasms; Mammary Neoplasms, Experimental; Mutation; Neoplasms, Experimental; Rats | 1976 |
[Increasing the sensitivity of in vitro transformed hamster embryo cells (STHE strain) to cytolysis by resident and activated macrophages].
Topics: Adjuvants, Immunologic; Animals; Ascitic Fluid; Cell Transformation, Neoplastic; Cricetinae; Culture Media; Cytotoxicity, Immunologic; Dactinomycin; Embryo, Mammalian; In Vitro Techniques; Macrophages; Neoplasms, Experimental | 1991 |
Effect of nicotinamide on hepatic microsomal drug metabolising system in tumour-bearing rats and mice.
Topics: Animals; Cytochrome P-450 Enzyme System; Dactinomycin; Female; Male; Mice; Mice, Inbred CBA; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Neoplasms, Experimental; Niacinamide; Pharmaceutical Preparations; Protein Biosynthesis; Rats; Rats, Inbred Strains | 1987 |
Rapid killing of actinomycin D-treated tumor cells by mononuclear phagocytes: characterization of effector cells in mice.
Topics: Animals; Antineoplastic Agents; Cell Line; Cytotoxicity, Immunologic; Dactinomycin; Fibroblasts; Hematopoietic Stem Cells; Humans; Macrophages; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Peritoneal Cavity; Pulmonary Alveoli; Species Specificity; Tumor Stem Cell Assay | 1986 |
Sorcin (V19), a soluble acidic calcium-binding protein overproduced in multidrug-resistant cells. Identification of the protein by anti-sorcin antibody.
Topics: Animals; Calcium; Calcium-Binding Proteins; Colchicine; Cricetinae; Cricetulus; Dactinomycin; Doxorubicin; Drug Resistance; Female; Fibroblasts; Gene Amplification; Humans; Immunoelectrophoresis; Lung; Mice; Mice, Inbred C57BL; Neoplasm Proteins; Neoplasms, Experimental; Neuroblastoma; Ovary; Vincristine | 1987 |
Correlation of macrophage-mediated tumor-cell lysis with the production of macrophage cytolytic factor (CF). Preliminary characterization of a factor inhibiting CF production.
Topics: Animals; Cytotoxicity, Immunologic; Cytotoxins; Dactinomycin; Female; Fibroblasts; Glycoproteins; Lipopolysaccharides; Macrophages; Mice; Mice, Inbred C3H; Neoplasms, Experimental; Proteins; Tumor Necrosis Factor-alpha | 1986 |
Glucan stimulates production of antitumor cytolytic/cytostatic factor(s) by macrophages.
Topics: Adenocarcinoma; Animals; Cell Division; Cells, Cultured; Cycloheximide; Cytotoxicity, Immunologic; Cytotoxins; Dactinomycin; Fibroblasts; Glucans; Glycoproteins; Hot Temperature; Macrophage Activation; Macrophages; Male; Mice; Monokines; Neoplasms, Experimental; Protease Inhibitors; Proteins; Tumor Necrosis Factor-alpha | 1986 |
Combination antitumor therapy with rabbit tumor necrosis factor and chemo- and immuno-therapeutic agents against murine tumors.
Topics: Animals; Antineoplastic Agents; Combined Modality Therapy; Dactinomycin; Doxorubicin; Glycoproteins; Growth Inhibitors; Lentinan; Liver Neoplasms, Experimental; Lung Neoplasms; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mitomycin; Mitomycins; Neoplasms, Experimental; Polysaccharides; Tumor Necrosis Factor-alpha | 1985 |
Drug-dependent cellular cytotoxicity mediated by polymorphonuclear leukocytes.
Topics: Animals; Antineoplastic Agents; Cytotoxicity, Immunologic; Dactinomycin; Erythrocytes; Hot Temperature; Male; Mice; Mice, Inbred C3H; Mice, Inbred DBA; Neoplasms, Experimental; Neutrophils; Spleen; Trypsin; Vincristine | 1985 |
[Tumor killing in cooperation with actinomycin D and neutrophils].
Topics: Animals; Cytotoxicity, Immunologic; Dactinomycin; Leukocyte Count; Mice; Mice, Inbred C3H; Neoplasms, Experimental; Neutrophils | 1986 |
Pleiotropic drug resistance and gene amplification in a SEWA mouse tumor cell line. Complex relations revealed by drug uptake data, and lipid and protein analysis.
Topics: Animals; Cell Line; Dactinomycin; Drug Resistance; Electrophoresis, Polyacrylamide Gel; Gene Amplification; Karyotyping; Lipids; Methotrexate; Mice; Neoplasms, Experimental; Phenotype; Temperature; Vincristine | 1985 |
Assessment of hormone action in cultured cells.
Topics: Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Line; Corticosterone; Dactinomycin; Enzyme Induction; Estradiol; Hydrocortisone; Hydroxyprogesterones; Immunoassay; In Vitro Techniques; Insulin; Liver Neoplasms; Neoplasms, Experimental; Rabbits; Rats; Tritium; Tyrosine Transaminase | 1971 |
[Estimation of tumor sensitivity in vitro. II. Studies with the solid Ehrlich carcinoma of the mouse and the GW 77, a heterotransplanted human carcinoma].
Topics: Animals; Antibiotics, Antineoplastic; Autoradiography; Carcinoma; Carcinoma, Ehrlich Tumor; Colonic Neoplasms; Cricetinae; Culture Media; Cytarabine; Dactinomycin; DNA, Neoplasm; Humans; Hydroxyurea; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Nucleosides; RNA, Neoplasm; Thymidine; Triaziquone; Tritium; Uridine | 1970 |
Inhibition of the processing of ribosomal precursor RNA by intercalating agents.
Topics: Acridines; Alkaloids; Animals; Antibiotics, Antineoplastic; Carbon Isotopes; Centrifugation, Density Gradient; Culture Techniques; Cycloheximide; Dactinomycin; Daunorubicin; Indoles; Lymphoma; Mice; Neoplasms, Experimental; Protein Binding; Protein Biosynthesis; Quaternary Ammonium Compounds; Quinolines; Ribosomes; RNA; RNA, Ribosomal; Sucrose; Uridine; Valine | 1971 |
Macrophage-melanoma cell heterokaryons. 3. The activation of macrophage DNA synthesis. Studies with inhibitors of protein synthesis and with synchronized melanoma cells.
Topics: Animals; Anti-Bacterial Agents; Cell Fusion; Cell Nucleus; Cells, Cultured; Cyclohexanes; Cycloheximide; Dactinomycin; DNA; Histocytochemistry; Leucine; Macrophages; Melanoma; Mice; Mitosis; Neoplasm Proteins; Neoplasms, Experimental; Peritoneum; Protein Biosynthesis; Pyridones; RNA, Neoplasm; Thymidine; Tritium; Uridine | 1971 |
Effect of various anticancer agents on DNA polymerase.
Topics: Adenosine Triphosphate; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Bleomycin; Bone Marrow; Carcinoma, Hepatocellular; Cytosine Nucleotides; Dactinomycin; Deoxyribonucleotides; DNA Nucleotidyltransferases; DNA, Neoplasm; Fluorouracil; Guanosine Triphosphate; Liver; Liver Neoplasms; Liver Regeneration; Mitomycins; Neoplasms, Experimental; Rats; Rifampin; Thymidine; Tritium | 1971 |
[Toxicity and cumulative properties of actinomycins C1, C2 and C3, contained in preparations in various combinations].
Topics: Animals; Body Weight; Cats; Dactinomycin; Depression, Chemical; Diarrhea; Feeding and Eating Disorders; Hemoglobins; Humans; Injections, Intraperitoneal; Injections, Intravenous; Isoleucine; Male; Mice; Neoplasms, Experimental; Stomatitis; Valine; Vomiting | 1971 |
[Effects of flavonoides and actinomycin D on proliferation and development of normal and neoplastic cells in vitro].
Topics: Animals; Catechols; Cell Count; Cell Division; Cell Transformation, Neoplastic; Cells; Dactinomycin; Diploidy; DNA; Extraembryonic Membranes; Flavonoids; Haplorhini; Humans; Kidney; Macaca; Mitosis; Mouth Neoplasms; Neoplasms, Experimental; RNA; Time Factors | 1971 |
Repression and derepression of purine biosynthesis in mammalian hepatoma cells in culture.
Topics: Acyltransferases; Adenine; Animals; Azacitidine; Carbon Isotopes; Carcinoma, Hepatocellular; Clone Cells; Cycloheximide; Dactinomycin; Feedback; Formates; Glycine; Kinetics; Ligases; Liver Neoplasms; Neoplasms, Experimental; Pentosephosphates; Pentosyltransferases; Purines; Rats; Ribonucleotides; Ribose; Tetrahydrofolates; Tritium | 1972 |
Synthesis and turnover of RNA in the 30-S nuclear ribonucleoprotein complexes of mouse ascites cells.
Topics: Animals; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Cell Nucleus; Cells, Cultured; Centrifugation, Density Gradient; Dactinomycin; DNA; Isotope Labeling; Kinetics; Liver; Liver Neoplasms; Mice; Neoplasm Proteins; Neoplasms, Experimental; Nucleoproteins; Phosphorus Isotopes; RNA; RNA, Neoplasm; Tritium | 1972 |
[Visualization of experimentally induced renal tumors in rats by pyelography and arteriography].
Topics: Angiography; Animals; Dactinomycin; Female; Kidney Neoplasms; Neoplasms, Experimental; Nitrosamines; Protein Deficiency; Rats; Urography | 1972 |
[Selective tumour chemotherapy using oncobiograms (author's transl)].
Topics: Animals; Antineoplastic Agents; Bleomycin; Cricetinae; Culture Techniques; Cytarabine; Dactinomycin; Daunorubicin; Doxorubicin; Drug Evaluation; Drug Resistance; Fluorouracil; Humans; Methods; Methotrexate; Neoplasm Transplantation; Neoplasms; Neoplasms, Experimental; Procarbazine; Radioisotopes; Rats; Scintillation Counting; Thymidine; Triaziquone; Uridine | 1974 |
Single strand scission and repair of DNA in bleomycin-sensitive and resistant rat ascites hepatoma cells.
Topics: Animals; Bleomycin; Carcinoma, Hepatocellular; Cells, Cultured; Centrifugation, Density Gradient; Cycloheximide; Dactinomycin; DNA Repair; DNA, Neoplasm; DNA, Single-Stranded; Drug Resistance; Liver Neoplasms; Neoplasms, Experimental; Rats; Sodium Dodecyl Sulfate; Thymidine; Tritium | 1973 |
Inhibition of ribosomal ribonucleic acid maturation by 5-azacytidine and 8-azaguanine in Novikoff hepatoma cells.
Topics: Animals; Azacitidine; Azaguanine; Carcinoma, Hepatocellular; Cells, Cultured; Cytidine; Dactinomycin; Electrophoresis, Polyacrylamide Gel; Fluorouracil; Guanosine; Isotope Labeling; Liver; Liver Neoplasms; Neoplasms, Experimental; Rats; RNA, Neoplasm; RNA, Ribosomal; Spectrophotometry, Ultraviolet; Time Factors; Tritium; Uridine | 1974 |
Regulation of tyrosine aminotrasferase activity in two liver-derived permanent cell lines.
Topics: Animals; Carcinoma, Hepatocellular; Cell Division; Cell Line; Dactinomycin; Demecolcine; Dexamethasone; Enzyme Induction; Kinetics; Liver; Liver Neoplasms; Mitosis; Neoplasms, Experimental; Rats; Time Factors; Tyrosine Transaminase | 1974 |
Interaction between hormones and cyclic AMP in regulating specific hepatic enzyme synthesis.
Topics: Adrenalectomy; Animals; Bucladesine; Carcinoma, Hepatocellular; Cell Line; Dactinomycin; Dexamethasone; Drug Interactions; Enzyme Induction; Glycogen; Insulin; Liver; Liver Neoplasms; Neoplasms, Experimental; Phosphoenolpyruvate Carboxykinase (GTP); Progesterone; Rats; Stimulation, Chemical; Tyrosine Transaminase | 1974 |
The role of messenger RNA in tyrosine aminotransferase superinduction: effects of camptothecin on hepatoma cells in culture.
Topics: Animals; Camptothecin; Carcinoma, Hepatocellular; Cells, Cultured; Dactinomycin; Deoxyadenosines; Enzyme Induction; Hydrocortisone; Insulin; Liver; Liver Neoplasms; Neoplasms, Experimental; Protein Biosynthesis; Rats; RNA, Messenger; Time Factors; Tyrosine Transaminase | 1974 |
Inhibition of messenger RNA accumulation but not translation in ultraviolet irradiated hepatoma cells.
Topics: Animals; Carcinoma, Hepatocellular; Cell Line; Dactinomycin; DNA, Neoplasm; Dose-Response Relationship, Radiation; Enzyme Induction; Hydrocortisone; Insulin; Leucine; Liver Neoplasms; Neoplasm Proteins; Neoplasms, Experimental; Protein Biosynthesis; Radiation Effects; Rats; RNA, Messenger; RNA, Neoplasm; Spectrophotometry, Ultraviolet; Thymidine; Time Factors; Transcription, Genetic; Tritium; Tyrosine Transaminase; Ultraviolet Rays; Uridine | 1974 |
Effect of actinomycin C on glucose-6-phosphate dehydrogenase activity of a human adenocarcinoma growing in a heterologous host.
Topics: Adenocarcinoma; Animals; Cricetinae; Dactinomycin; Glucosephosphate Dehydrogenase; Humans; In Vitro Techniques; Neoplasms; Neoplasms, Experimental | 1965 |
Tumour glucose-6-phosphate dehydrogenase inhibition by actinomycin.
Topics: Animals; Colonic Neoplasms; Cricetinae; Dactinomycin; Glucosephosphate Dehydrogenase; Liver; Neoplasm Transplantation; Neoplasms, Experimental | 1967 |
[On the cytostatic treatment of plasmocytoma in gold hamster].
Topics: Animals; Azirines; Cricetinae; Dactinomycin; Neoplasms, Experimental; Plasmacytoma; Triaziquone | 1966 |
Carcinogenesis and gene action. Franz Bielschowsky Memorial Lecture.
Topics: Animals; Azo Compounds; Carcinogens; Dactinomycin; DNA; Enzyme Induction; Genes; Liver; Methylcholanthrene; Mixed Function Oxygenases; Molecular Biology; Neoplasms; Neoplasms, Experimental; Phenobarbital; Phenotype; Puromycin; Rats; RNA; RNA Nucleotidyltransferases | 1968 |
[On the experimental chemotherapy of a human adenocarcinoma in the cheek pouch of the Golden hamster: the effect of actinomycin C].
Topics: Adenocarcinoma; Animals; Colonic Neoplasms; Cricetinae; Dactinomycin; Humans; Mathematics; Neoplasm Transplantation; Neoplasms, Experimental | 1966 |
[Primary selection of the producers of antineoplastic antibiotics specifically interacting with nucleic acids].
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Bacteriophages; Culture Techniques; Dactinomycin; Daunorubicin; DNA; DNA, Bacterial; Flavonoids; Humans; Mannomustine; Methods; Mice; Neoplasms; Neoplasms, Experimental; Nucleic Acids; Rabbits; Rats; RNA; Staphylococcus; Streptomyces | 1966 |
[Growth stimulation by sibliminal concentrations of growth-inhibiting substances].
Topics: Anilides; Animals; Bacteria; Chick Embryo; Dactinomycin; Extraembryonic Membranes; Growth Substances; Neoplasms, Experimental; Neurospora; Plants, Medicinal; Plants, Toxic; Podophyllin; Podophyllum; Pyrimidines; Thalidomide | 1966 |
[To the problem of the stimulation of the growth of transplantable tumors of animals previously treated with antineoplastic antibiotics].
Topics: Animals; Antibiotics, Antineoplastic; Dactinomycin; Male; Melanoma; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Olivomycins; Rats; Sarcoma; Sarcoma 37 | 1968 |
[Combined action of roentgen radiation and antineoplastic antibiotics (chrysomallin, olivomycin) on the transplantable tumors of animals].
Topics: Animals; Antibiotics, Antineoplastic; Dactinomycin; Male; Melanoma; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Olivomycins; Rats; Sarcoma | 1968 |
Mengovirus replication in Novikoff rat hepatoma and mouse L cells: effects on synthesis of host-cell macromolecules and virus-specific synthesis of ribonucleic acid.
Topics: Animals; Carcinoma, Hepatocellular; Culture Techniques; Dactinomycin; Encephalomyocarditis virus; L Cells; Liver Neoplasms; Mice; Neoplasm Proteins; Neoplasms, Experimental; Proteins; RNA; RNA Nucleotidyltransferases; RNA, Neoplasm; RNA, Viral; Virus Diseases; Virus Replication | 1968 |
Production, biological and therapeutic properties of some individual actinomycins.
Topics: Amino Acid Sequence; Animals; Antibiotics, Antineoplastic; Dactinomycin; Leucine; Mice; Neoplasms, Experimental; Valine | 1968 |
Chemotherapy of induced skin tumors in mice.
Topics: Alkylating Agents; Animals; Antimetabolites; Antineoplastic Agents; Benz(a)Anthracenes; Busulfan; Carcinoma, Squamous Cell; Chlorambucil; Cortisone; Cyclophosphamide; Dactinomycin; Estradiol; Female; Fluorouracil; Hydroxyurea; Mercaptopurine; Methotrexate; Mice; Mitomycins; Neoplasms, Experimental; Nitrogen Mustard Compounds; Nitroso Compounds; Papilloma; Skin Neoplasms; Testosterone; Triethylenemelamine | 1968 |
[Tumor-host relations in the comprehension of chemotherapeutic effects].
Topics: Animals; Antineoplastic Agents; Cheek; Cricetinae; Dactinomycin; Humans; Hyperemia; Neoplasm Transplantation; Neoplasms, Experimental; Phytotherapy; Plants, Medicinal; Plants, Toxic; Podophyllin; Podophyllum; Transplantation, Heterologous | 1968 |
Segregation of the nucleolar materials produced by quinoxaline antibiotics in JTC-13 cells. Comparison of effects among 4-nitro-quinoline 1-oxide, actinomycin-B, and quinoxaline antibiotics.
Topics: Animals; Anti-Bacterial Agents; Cell Nucleolus; Cell Nucleus; Culture Techniques; Cytoplasm; Dactinomycin; Female; Mice; Microscopy, Electron; Neoplasms, Experimental; Nitroso Compounds; Quinolines; Quinoxalines | 1968 |
[On the question of preclinical selection of cytostatics in the area of treatment of human tumors].
Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Carcinoma 256, Walker; Cricetinae; Culture Techniques; Dactinomycin; Depression, Chemical; DNA, Neoplasm; Fluorouracil; Humans; Lung Neoplasms; Methods; Methotrexate; Neoplasms; Neoplasms, Experimental; Radionuclide Imaging; Rats; RNA, Neoplasm; Stimulation, Chemical; Thymidine; Triaziquone; Tritium; Vinblastine; Vincristine | 1969 |
Lymphocytes, anti-tumour agents, and target cells.
Topics: Agglutination Tests; Animals; Antineoplastic Agents; Culture Techniques; Dactinomycin; Fibroblasts; Hydroxylamines; Immune Sera; Lectins; Lymphocytes; Methotrexate; Mice; Mitomycins; Neoplasms, Experimental; Prednisolone | 1969 |
[Testing of cytostatic agents on individual tumors].
Topics: Animals; Antineoplastic Agents; Autoradiography; Dactinomycin; Methods; Neoplasms, Experimental; Nucleosides; Rats; Sarcoma, Experimental; Thymidine; Triaziquone; Tritium; Uridine | 1968 |
[Enzyme variations in tumors following carcinostatic therapy of human colonic tumors in golden hamsters].
Topics: Adenocarcinoma; Animals; Cheek; Colonic Neoplasms; Cricetinae; Cyclophosphamide; Dactinomycin; Female; Glucosephosphate Dehydrogenase; Glycolysis; Humans; Injections, Intraperitoneal; L-Lactate Dehydrogenase; Liver; Male; Neoplasm Transplantation; Neoplasms, Experimental; Pentoses; RNA | 1969 |
[Injury of bone marrow after local irradiation of tumor and administration of chrysomalline].
Topics: Animals; Bone Marrow; Bone Marrow Cells; Dactinomycin; Male; Melanoma; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Radiation Effects | 1969 |
Synthesis of the ninth component of complement by a clonal strain of rat hepatoma cells.
Topics: Animals; Carcinoma, Hepatocellular; Centrifugation, Density Gradient; Clone Cells; Complement System Proteins; Culture Media; Culture Techniques; Cycloheximide; Dactinomycin; Hemolysis; Hydrocortisone; Liver Neoplasms; Neoplasms, Experimental; Protein Biosynthesis; Rats; RNA; Temperature | 1970 |
The growth of human tumours in immunosuppressed mice and their response to chemotherapy.
Topics: Animals; Chlorambucil; Cyclophosphamide; Dactinomycin; Disease Models, Animal; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Immunosuppression Therapy; Male; Melphalan; Methotrexate; Mice; Mice, Inbred CBA; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms, Experimental; Ovarian Neoplasms; Thiotepa; Thymectomy; Transplantation, Heterologous; Triaziquone; Urinary Bladder Neoplasms; Vinblastine; Vincristine | 1974 |
Chemotherapy studies in an animal tumor spectrum. II. Sensitivity of tumors to fourteen antitumor chemicals.
Topics: Animals; Antineoplastic Agents; Arsenicals; Busulfan; Cyclophosphamide; Dactinomycin; Diethylstilbestrol; Floxuridine; Fluorouracil; Hydrocortisone; Mercaptopurine; Methotrexate; Mice; Mitomycins; Neoplasms, Experimental; Urethane; Vinblastine | 1966 |
Myeloid leukemia C-1498 as a screen for cancer chemotherapeutic agents.
Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Azaguanine; Azaserine; Busulfan; Cyclophosphamide; Dactinomycin; Female; Floxuridine; Fluorouracil; Leukemia, Experimental; Mercaptopurine; Methotrexate; Mice; Neoplasms, Experimental; Prednisone; Pyrazoles; Pyrimidines; Triethylenemelamine; Vinblastine; Vincristine | 1966 |
[Effects of cytostatics and x-rays on nucleic acid metabolism of solid, malignant tumors in vitro].
Topics: Adenine; Animals; Antineoplastic Agents; Carbon Isotopes; Dactinomycin; Depression, Chemical; DNA, Neoplasm; Estriol; Fluorouracil; Formates; Glycine; Hypoxanthines; In Vitro Techniques; Leucine; Mercaptopurine; Methotrexate; Methylprednisolone; Neoplasm Proteins; Neoplasms, Experimental; Nucleosides; Orotic Acid; Radiation Effects; RNA, Neoplasm; Testosterone; Thymidine; Triaziquone; Uracil; Uridine | 1970 |
Growth inhibition by chemotherapeutic agents on stilbestrol-induced hamster kidney tumor.
Topics: Adenocarcinoma; Animals; Cricetinae; Cyclophosphamide; Dactinomycin; Diethylstilbestrol; Fluorouracil; Kidney Neoplasms; Male; Neoplasms, Experimental; Plicamycin; Vincristine | 1971 |
Cell cycle phase specificity of antitumor agents.
Topics: Alkaloids; Alkylating Agents; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Carbazoles; Cell Line; Chlorambucil; Cricetinae; Cytarabine; Dactinomycin; Depression, Chemical; DNA; Fibroblasts; Floxuridine; In Vitro Techniques; Lung; Melphalan; Mitosis; Neoplasms, Experimental; Nitrosourea Compounds; Nucleosides; Protein Biosynthesis; RNA; Streptozocin; Thiosemicarbazones | 1972 |
Studies on a reciprocal relationship between nucleoside kinases and 5'-nucleotidase.
Topics: Adenosine Triphosphatases; Animals; Bone Marrow; Bone Marrow Cells; Carbon Isotopes; Cytidine; Cytosine Nucleotides; Dactinomycin; Deoxyribonucleotides; Depression, Chemical; Kidney; Liver; Liver Regeneration; Male; Microsomes, Liver; Neoplasms, Experimental; Nucleotidases; Phosphotransferases; Rats; Thymidine; Thymine Nucleotides; Uracil Nucleotides; Uridine | 1972 |
Polyribosomes in rat tissues. IV. On the abnormal dimer peak in hepatomas.
Topics: Animals; Carbon Isotopes; Carbon Tetrachloride; Carcinoma, Hepatocellular; Dactinomycin; In Vitro Techniques; Leucine; Liver Neoplasms; Neoplasms, Experimental; Rats; Ribosomes; RNA, Messenger; Temperature; Ultracentrifugation | 1966 |
Replication of mengovirus. I. Effect on synthesis of macromolecules by host cell.
Topics: Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Culture Techniques; Dactinomycin; DNA; Encephalomyocarditis virus; Liver Neoplasms; Neoplasms, Experimental; Protein Biosynthesis; Rats; Ribonucleases; RNA; RNA, Viral; Ultracentrifugation; Viral Interference | 1966 |
Replication of mengovirus. II. General properties of the viral-induced ribonucleic acid polymerase.
Topics: Animals; Carbon Isotopes; Culture Techniques; Dactinomycin; DNA; Encephalomyocarditis virus; Hematoma; Neoplasms, Experimental; Nucleotides; Nucleotidyltransferases; Puromycin; Rats; RNA; Temperature; Uridine | 1966 |
Different effects of chloramphenicol, dactinomycin, and streptovitacin A on synthesis of tumor and virion antigens in SV40 virus-infected cells.
Topics: Antibiotics, Antineoplastic; Antigens; Chloramphenicol; Cytopathogenic Effect, Viral; Dactinomycin; Neoplasms, Experimental; Simian virus 40 | 1966 |
Nucleolar changes in KB tumor cells infected with herpes simplex virus.
Topics: Cell Nucleolus; Culture Techniques; Dactinomycin; Microscopy, Electron; Mitomycins; Neoplasms, Experimental; Quinolines; RNA, Viral; Simplexvirus | 1967 |
Polyribosome breakdown in rat liver following administration of 8-azaguanine.
Topics: Animals; Azaguanine; Carbon Isotopes; Carcinoma, Hepatocellular; Dactinomycin; Liver; Liver Neoplasms; Male; Neoplasms, Experimental; Orotic Acid; Rats; Ribosomes; RNA, Messenger | 1967 |
Priming activity for RNA synthesis of chromatin from transplantable hepatomas and livers of tumor-bearing rats.
Topics: Animals; Carcinoma, Hepatocellular; Chromosomes; Dactinomycin; Liver; Liver Neoplasms; Male; Neoplasm Transplantation; Neoplasms, Experimental; Quaternary Ammonium Compounds; Rats; RNA, Neoplasm | 1967 |
On the mechanism of phenethyl alcohol-induced loss of polyribosomes and their re-formation after reversal in rat hepatoma cells.
Topics: Amino Acids; Animals; Antineoplastic Agents; Carbon Isotopes; Carcinoma, Hepatocellular; Centrifugation, Density Gradient; Culture Techniques; Cycloheximide; Dactinomycin; Ethanol; Liver Neoplasms; Neoplasm Proteins; Neoplasms, Experimental; Rats; Ribosomes; RNA, Messenger; Spectrophotometry; Time Factors; Tritium; Uridine | 1968 |
Diversity and nature of ribosomal pools in hepatoma 7800 and host liver.
Topics: Animals; Azaguanine; Carbon Isotopes; Carbon Tetrachloride; Carcinoma, Hepatocellular; Dactinomycin; Ferritins; Liver; Liver Neoplasms; Neoplasms, Experimental; Orotic Acid; Puromycin; Rats; Ribosomes | 1968 |
Two deoxyribonucleases from Novifoff ascites hepatoma cells.
Topics: Animals; Antibiotics, Antineoplastic; Carcinoma, Hepatocellular; Chromatography; Dactinomycin; Deoxyribonucleases; Edetic Acid; Heparin; Hydrogen-Ion Concentration; Liver Neoplasms; Magnesium; Neoplasms, Experimental; Phosphoric Monoester Hydrolases; Rats; Sulfhydryl Compounds; Temperature | 1968 |
Effects of actinomycin D on the oligonucleotide composition of nucleolar 45-S RNA of Novikoff hepatoma ascites cells.
Topics: Adenine Nucleotides; Animals; Carcinoma, Hepatocellular; Cell Nucleolus; Centrifugation, Density Gradient; Cytosine Nucleotides; Dactinomycin; Depression, Chemical; Guanine Nucleotides; Hydrogen-Ion Concentration; Liver Neoplasms; Male; Neoplasms, Experimental; Nucleotides; Phosphates; Phosphorus Isotopes; Rats; Ribonucleases; RNA; Solubility; Spectrophotometry; Uracil Nucleotides | 1969 |
Hormonal effect on nucleolar RNA polymerase in normal liver and hepatoma cells.
Topics: Animals; Carcinoma, Hepatocellular; Cell Nucleolus; Dactinomycin; Estradiol; Estrogens; Glucocorticoids; Hydrocortisone; Liver; Liver Neoplasms; Neoplasms, Experimental; Nucleotidyltransferases; Prednisolone; Rats; RNA, Neoplasm | 1968 |
Antitumor effect of actinomycin-D on transplantable Wilms tumor in rats.
Topics: Animals; Ascites; Carcinoma, Hepatocellular; Dactinomycin; Injections, Intraperitoneal; Injections, Subcutaneous; Liver Neoplasms; Neoplasm Transplantation; Neoplasms, Experimental; Rats; Wilms Tumor | 1968 |
Relationship between uridine kinase activity and rate of incorporation of uridine into acid-soluble pool and into RNA during growth cycle of rat hepatoma cells.
Topics: Animals; Carcinoma, Hepatocellular; Cell-Free System; Chromatography, Paper; Culture Media; Culture Techniques; Cycloheximide; Dactinomycin; Depression, Chemical; Electrophoresis; Liver Neoplasms; Mitosis; Neoplasms, Experimental; Phosphotransferases; Proteins; Puromycin; RNA, Neoplasm; Tritium; Uridine | 1969 |
[Ribonucleic acids and proteins from cells infected by mouse encephalomyocarditis virus (EMC) in the presence of pyronine].
Topics: Amino Acids; Animals; Carbon Isotopes; Centrifugation, Density Gradient; Dactinomycin; Encephalomyocarditis virus; Mice; Neoplasms, Experimental; Quaternary Ammonium Compounds; RNA, Viral; Time Factors; Tritium; Uridine; Viral Proteins | 1969 |
Increase of glycogen and oligosaccharide contents in ascites tumor cells under the influence of alkylating agents.
Topics: Alkylating Agents; Animals; Antineoplastic Agents; Ascites; Carcinoma, Hepatocellular; Cobalt Isotopes; Colchicine; Cyclophosphamide; Dactinomycin; Female; Glycogen; Liver Neoplasms; Mechlorethamine; Mercaptopurine; Mitomycins; Neoplasm Transplantation; Neoplasms, Experimental; Oligosaccharides; Rats; Sarcoma, Yoshida | 1969 |
Induction of glutamine synthetase by cortisol.
Topics: Adrenal Glands; Adrenalectomy; Ammonia; Aniline Compounds; Animals; Azo Compounds; Carcinoma 256, Walker; Carcinoma, Hepatocellular; Dactinomycin; Depression, Chemical; Dietary Proteins; Enzyme Induction; Glutamine; Hydrocortisone; Ligases; Liver; Liver Neoplasms; Lymphoma, Non-Hodgkin; Male; Neoplasm Transplantation; Neoplasms, Experimental; p-Dimethylaminoazobenzene; Rats; Starvation; Stimulation, Chemical; Time Factors | 1968 |
[Electron microscope localization of the activity of certain nucleases in ultrathin serial sections].
Topics: Acid Phosphatase; Alkaline Phosphatase; Animals; Carcinoma, Hepatocellular; Cell Nucleus; Dactinomycin; Deoxyribonucleases; Histocytochemistry; In Vitro Techniques; Kidney; Liver; Liver Neoplasms; Membranes; Methods; Microscopy, Electron; Neoplasms, Experimental; Pancreas; Polyvinyls; Rats; Ribonucleases; Sex Chromatin | 1970 |
Benzpyrene hydroxylase activity and its induction by methylcholanthrene in Morris hepatomas, in host livers, in adult livers, and in rat liver during development.
Topics: Animals; Benzopyrenes; Carcinoma, Hepatocellular; Cycloheximide; Dactinomycin; Enzyme Induction; Female; Liver; Liver Neoplasms; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Neoplasms, Experimental; Puromycin; Rats | 1970 |
The effect of methotrexate and dactinomycin on transplantable malignant and benign trophoblastic growths.
Topics: Animals; Cheek; Choriocarcinoma; Cricetinae; Dactinomycin; Disease Models, Animal; Drug Synergism; Female; Humans; Methotrexate; Neoplasm Transplantation; Neoplasms, Experimental; Pregnancy; Trophoblastic Neoplasms | 1970 |
Encephalomyocarditis virus multiplication in the presence of pyronine.
Topics: Amino Acids; Animals; Ascitic Fluid; Carbon Isotopes; Coloring Agents; Culture Techniques; Dactinomycin; Encephalomyocarditis virus; Genetics, Microbial; Mice; Neoplasms, Experimental; Rats; RNA, Viral; Templates, Genetic; Tritium; Uridine; Viral Proteins; Virus Cultivation; Virus Replication; Xanthines | 1970 |
Studies on the mechanism of template stability: cytoplasmic DNA-like RNA in hepatocellular carcinomas.
Topics: Adenine Nucleotides; Animals; Carcinoma, Hepatocellular; Cell Membrane; Centrifugation, Density Gradient; Cytoplasm; Dactinomycin; DNA; DNA, Neoplasm; Female; Liver Neoplasms; Male; Microscopy, Electron; Microsomes; Neoplasms, Experimental; Phosphorus Isotopes; Rats; RNA; RNA, Neoplasm; Templates, Genetic | 1970 |
Adrenal cells in tissue culture. VII. The effect of inhibitors of protein synthesis on steroidogenesis and glycolysis.
Topics: Acetates; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Animals; Carbon Isotopes; Cell-Free System; Cholesterol; Culture Techniques; Cycloheximide; Dactinomycin; Depression, Chemical; Glycolysis; Leucine; Lysine; Mice; Neoplasm Proteins; Neoplasms, Experimental; Pregnenolone; Puromycin; RNA, Neoplasm; Tritium; Uridine | 1970 |
Induction of SV40 transplantation antigen (TrAg) during the lytic cycle.
Topics: Animals; Animals, Newborn; Antigens; Bromodeoxyuridine; Cell Line; Cricetinae; Cycloheximide; Cytarabine; Cytopathogenic Effect, Viral; Dactinomycin; Female; Floxuridine; Fluorescent Antibody Technique; Haplorhini; Immune Tolerance; Immunity; Immunization; Kidney; Male; Neoplasms, Experimental; Neutralization Tests; Puromycin; Simian virus 40; Time Factors | 1970 |
Responsiveness of glutamine-metabolizing enzymes in Morris hepatomas to metabolic modulations.
Topics: Adrenalectomy; Animal Feed; Animals; Animals, Laboratory; Carcinoma, Hepatocellular; Cell Line; Chromosomes; Dactinomycin; Dietary Proteins; Enzyme Activation; Glutaminase; Glutamine; Hydrocortisone; Ligases; Liver Neoplasms; Neoplasm Transplantation; Neoplasms, Experimental; Rats; Thyroxine; Transaminases; Transplantation, Homologous | 1970 |
Isolation of two small molecular weight RNA components by MAK column chromatography.
Topics: Albumins; Animals; Carcinoma; Carcinoma, Ehrlich Tumor; Cell Nucleus; Centrifugation, Density Gradient; Chromatography; Cytoplasm; Dactinomycin; Metabolism; Methionine; Mice; Molecular Weight; Neoplasms, Experimental; Nucleosides; Nucleotides; Phenols; Phosphorus Isotopes; Ribosomes; RNA, Neoplasm; RNA, Transfer; Silicon Dioxide; Tritium; Uridine | 1971 |
[Actinomycin D binding with the DNA of some transplantable tumors].
Topics: Animals; Carcinoma, Hepatocellular; Dactinomycin; DNA; DNA, Neoplasm; Liver; Liver Neoplasms; Lymphoma, Non-Hodgkin; Mice; Neoplasms, Experimental; Rats; Thymus Gland | 1971 |
Behavior of opposing pathways of thymidine utilization in differentiating, regenerating, and neoplastic liver.
Topics: Animals; Animals, Newborn; Carbon Dioxide; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Differentiation; Culture Techniques; Dactinomycin; DNA; DNA Replication; DNA, Neoplasm; Hepatectomy; Liver; Liver Neoplasms; Liver Regeneration; Male; Neoplasms, Experimental; Rats; Thymidine | 1971 |
Infection of tumour cells by fowl plague virus in the presence of actinomycin D.
Topics: Animals; Cell Transformation, Neoplastic; Culture Techniques; Dactinomycin; Hemagglutinins, Viral; Influenza A virus; Mice; Neoplasms, Experimental; Polyomavirus; RNA, Viral; Virus Replication | 1971 |
Modification of the effect of vitamin A acid on the skin tumor keratoacanthoma by applications of actinomcin D.
Topics: Animals; Benz(a)Anthracenes; Dactinomycin; Endoplasmic Reticulum; Glycogen; Golgi Apparatus; Inclusion Bodies; Keratoacanthoma; Macrophages; Male; Microscopy, Electron; Mucus; Neoplasms, Experimental; Rabbits; Ribosomes; Skin; Skin Neoplasms; Vitamin A | 1971 |
Synthesis of capsid and noncapsid viral proteins in response to encephalomyocarditis virus ribonucleic acid in animal cell-free systems.
Topics: Animals; Autoradiography; Carbon Isotopes; Cell Line; Cell-Free System; Chromatography; Dactinomycin; Electrophoresis, Disc; Encephalomyocarditis virus; Genetic Code; Genetics, Microbial; Hydrolysis; Isoelectric Focusing; L Cells; Leucine; Methionine; Mice; Molecular Weight; Neoplasms, Experimental; Peptide Biosynthesis; Peptides; RNA, Viral; Sulfur Isotopes; Trypsin; Viral Proteins | 1971 |
Mechanisms in cellular metabolic regulation.
Topics: Animals; Animals, Newborn; Carcinoma, Hepatocellular; Cortisone; Dactinomycin; Diabetes Mellitus, Experimental; Diet; Fasting; Glucagon; Hydro-Lyases; Isoenzymes; L-Serine Dehydratase; Leucine; Liver; Liver Neoplasms; Models, Biological; Molecular Biology; Neoplasms, Experimental; Rats; RNA, Messenger; Tritium | 1971 |
Synthesis of cell coat in normal and transformed cells.
Topics: Animals; Cell Line; Cell Membrane; Cell Transformation, Neoplastic; Cells, Cultured; Cycloheximide; Dactinomycin; Glycoproteins; Kinetics; Leucine; Methylcholanthrene; Mice; Neoplasms, Experimental; Polyomavirus; RNA, Neoplasm; Tritium | 1972 |
Studies on rat liver catalase. V. Incorporation of 14 C-leucine into catalase by isolated rat liver ribosomes.
Topics: Acetamides; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Catalase; Cell-Free System; Cycloheximide; Dactinomycin; Depression, Chemical; In Vitro Techniques; Leucine; Liver; Liver Neoplasms; Male; Neoplasms, Experimental; Nucleotides; Puromycin; Rats; Ribonucleases; Ribosomes; Triazoles | 1971 |
Induction and threatment of Wilms tumor by transplantation of renal blastema in a new experimental model.
Topics: Animals; Dactinomycin; Disease Models, Animal; Female; Kidney; Kidney Neoplasms; Kidney Transplantation; Lung; Male; Mice; Mice, Inbred Strains; Microscopy, Electron; Neoplasm Transplantation; Neoplasms, Experimental; Pregnancy; Testis; Transplantation, Homologous; Vincristine; Wilms Tumor | 1972 |
Association of exogenous RNA with Novikoff hepatoma ascites cells.
Topics: Animals; Ascites; Autoradiography; Carcinoma, Hepatocellular; Cell Fractionation; Centrifugation, Density Gradient; Cytosine Nucleotides; Dactinomycin; Dextrans; Electrophoresis, Disc; Guanosine; Liver Neoplasms; Methods; Neoplasm Transplantation; Neoplasms, Experimental; Nucleotides; Phosphorus Isotopes; Rats; Rats, Inbred Strains; Ribonucleases; RNA; Time Factors | 1972 |
Inhibitors of cyclic-nucleotide phosphodiesterase induce morphological differentiation of mouse neuroblastoma cell culture.
Topics: Animals; Axons; Benzyl Compounds; Cell Count; Cell Differentiation; Cells, Cultured; Culture Media; Cycloheximide; Dactinomycin; Ethers; Imidazoles; Ketones; Methyl Ethers; Mice; Mycotoxins; Neoplasms, Experimental; Neuroblastoma; Papaverine; Phosphodiesterase Inhibitors; Phosphoric Monoester Hydrolases; Theophylline; Time Factors; Vinblastine | 1972 |
Collagenase in carcinoma cells.
Topics: Animals; Carcinoma; Centrifugation; Culture Media; Culture Techniques; Dactinomycin; DNA, Neoplasm; Hydroxyproline; Membranes; Microbial Collagenase; Neoplasm Transplantation; Neoplasms, Experimental; Neoplasms, Muscle Tissue; Nucleotidases; Rabbits; Solubility; Time Factors; Tumor Virus Infections | 1972 |
Control of phenotypic expression of cultured melanoma cells by melanocyte stimulating hormones.
Topics: Animals; Butyrates; Catechol Oxidase; Cell Division; Cell Line; Cyclic AMP; Cycloheximide; Dactinomycin; DNA, Neoplasm; Melanins; Melanocyte-Stimulating Hormones; Melanoma; Mice; Neoplasms, Experimental; Phenotype; Protein Biosynthesis; RNA, Neoplasm; Transcription, Genetic; Tritium | 1973 |
Modified hormonal control of enzymatic activity in tumors.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Adrenalectomy; Animals; Carcinoma, Hepatocellular; Castration; Dactinomycin; Diabetes Mellitus, Experimental; Diet; Dietary Carbohydrates; Estradiol; Fasting; Female; Glucosephosphate Dehydrogenase; Gonadal Steroid Hormones; Hydrocortisone; Insulin, Long-Acting; Liver; Liver Neoplasms; Neoplasm Transplantation; Neoplasms, Experimental; Ovary; Phosphotransferases; Progesterone; Pyruvate Kinase; Rats; Testosterone | 1973 |
The induction of ornithine decarboxylase in cultured hepatoma cells.
Topics: Animals; Carboxy-Lyases; Carcinoma, Hepatocellular; Culture Techniques; Dactinomycin; Enzyme Induction; Half-Life; Liver Neoplasms; Neoplasms, Experimental; Ornithine; Rats | 1972 |
Ganglioside patterns and phenotypic characteristics in a normal variant and a transformed back variant of a simian virus 40-induced hamster tumor cell line.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Cricetinae; Dactinomycin; Galactosamine; Gangliosides; Neoplasms, Experimental; Neuraminic Acids; Phenotype; Simian virus 40 | 1973 |
Expression of malignancy in interspecies Chinese hamster X mouse cell hybrids.
Topics: Animals; Antigens; Antigens, Neoplasm; Bromodeoxyuridine; Cell Fusion; Cell Line; Cell Membrane; Cell Transformation, Neoplastic; Chick Embryo; Cricetinae; Dactinomycin; Drug Resistance; Graft Rejection; Histocompatibility Antigens; Hybrid Cells; Karyotyping; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Neoplasms, Experimental; Retroviridae; Transplantation, Heterologous | 1973 |
The role of macrophages in the cytotoxic killing of tumour cells in vitro. I. Primary immunization of lymphocytes in vitro for target cell killing and the mechanism of lymphocyte-macrophage cooperation.
Topics: Animals; Antigen-Antibody Reactions; Carcinoma, Ehrlich Tumor; Chromium Radioisotopes; Cobalt Radioisotopes; Cytotoxicity Tests, Immunologic; Dactinomycin; Female; Leukemia L1210; Lymph Nodes; Lymphocytes; Macrophages; Male; Mice; Mice, Inbred CBA; Mice, Inbred DBA; Neoplasms, Experimental; Polyomavirus; Puromycin; Spleen; Trypsin | 1973 |
Effect of actinomycin D on uptake and incorporation of thymidine and hypoxanthine into the acid-soluble and acid-insoluble fractions of rat hepatoma cells grown in culture.
Topics: Animals; Carcinoma, Hepatocellular; Cells, Cultured; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Hypoxanthines; Kinetics; Liver Neoplasms; Neoplasms, Experimental; Rats; Stimulation, Chemical; Thymidine; Thymidine Kinase; Time Factors; Tritium; Uridine | 1974 |
Combination therapy: some concepts and results.
Topics: Animals; Antineoplastic Agents; Child; Cyclohexanes; Cyclophosphamide; Cytarabine; Dactinomycin; Drug Resistance; Drug Synergism; Drug Therapy, Combination; Humans; Imidazoles; Leukemia L1210; Lung Neoplasms; Melanoma; Mice; Neoplasm Metastasis; Neoplasms; Neoplasms, Experimental; Nitrogen Mustard Compounds; Nitrosourea Compounds; Thioguanine; Triazenes; Wilms Tumor | 1974 |
Effect of uridine on de novo pyrimidine biosynthesis in rat hepatoma cells in culture.
Topics: Amidohydrolases; Animals; Aspartate Carbamoyltransferase; Carbamates; Carbon Dioxide; Carbon Radioisotopes; Carboxy-Lyases; Carcinoma, Hepatocellular; Clone Cells; Cycloheximide; Dactinomycin; DNA, Neoplasm; Glutamine; Kinetics; Liver Neoplasms; Neoplasms, Experimental; Orotic Acid; Pentosyltransferases; Phosphotransferases; Pyrimidine Nucleotides; Rats; Ribonucleotides; RNA, Neoplasm; Uridine | 1974 |
A re-examination of the renal blastema graft model for Wilms tumor production.
Topics: Animals; Autopsy; Cell Differentiation; Cyclophosphamide; Dactinomycin; Disease Models, Animal; Drug Therapy, Combination; Female; Fetus; Fluorouracil; Kidney; Kidney Neoplasms; Kidney Transplantation; Male; Methotrexate; Mice; Mice, Inbred Strains; Microscopy, Electron; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms, Experimental; Pregnancy; Testicular Neoplasms; Transplantation, Homologous; Vincristine; Wilms Tumor | 1974 |
The susceptibility of the fetus and child to chemical pollutants. Viral etiology of cancer: two hypotheses with relevance to chemical exposures.
Topics: Animals; Avian Sarcoma Viruses; Carcinogens; Cats; Cell Transformation, Neoplastic; Chick Embryo; Chickens; Clone Cells; Cricetinae; Dactinomycin; DNA; Genes, Regulator; Mice; Molecular Biology; Mutagens; Neoplasms; Neoplasms, Experimental; Oncogenic Viruses; RNA, Messenger; Virus Replication | 1974 |
Mechanisms by which activated normal macrophages destroy syngeneic rat tumour cells in vitro. Cytokinetics, non-involvement of T lymphocytes, and effect of metabolic inhibitors.
Topics: Agglutination; Animals; Antimetabolites; Benz(a)Anthracenes; Cell Aggregation; Cells, Cultured; Cycloheximide; Cytochalasin B; Dactinomycin; DNA; Enzymes; Guinea Pigs; Immune Tolerance; Kinetics; Macrophages; Methylcholanthrene; Neoplasms, Experimental; Polyomavirus; Rats; Silicon Dioxide; T-Lymphocytes; Thymidine; Time Factors; Tritium | 1974 |
Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in hepatoma tissue culture cells by serum lipoproteins.
Topics: Alcohol Oxidoreductases; Animals; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cattle; Cell Line; Chromatography, Thin Layer; Coenzyme A; Culture Media; Cycloheximide; Dactinomycin; Enzyme Activation; Glutarates; Half-Life; Kinetics; Lipoproteins; Liver Neoplasms; Mevalonic Acid; Microsomes; Neoplasms, Experimental; Rats; Time Factors; Tritium; Ultracentrifugation | 1974 |
Effect of metabolic inhibitors on killing of tumor cells by antibody and complement.
Topics: Animals; Antigen-Antibody Reactions; Antimetabolites; Carcinoma, Hepatocellular; Cell Line; Complement System Proteins; Cytotoxicity Tests, Immunologic; Dactinomycin; Guinea Pigs; Hydroxyurea; Liver Neoplasms; Mitomycins; Neoplasms, Experimental; Puromycin; Rabbits; Stimulation, Chemical | 1974 |
Acinomycin D and purine transport in cultured rat hepatoma cells.
Topics: Adenine; Animals; Biological Transport, Active; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cells, Cultured; Clone Cells; Culture Media; Cycloheximide; Dactinomycin; Guanine; Guanosine; Hypoxanthines; Kinetics; Liver Neoplasms; Neoplasms, Experimental; Pentosyltransferases; Purines; Rats | 1974 |
Studies on the mechanism of actinomycin D resistance of an SV40-transformed hamster cell line.
Topics: Amino Acids; Animals; Cell Line; Cell Transformation, Neoplastic; Cricetinae; Dactinomycin; Dextrans; Drug Resistance; Neoplasms, Experimental; Ornithine; Peptides; Permeability; Puromycin; RNA, Neoplasm; Simian virus 40; Time Factors; Transcription, Genetic; Tritium; Uridine | 1974 |
Release of cytoplasmic enzymes into culture fluid.
Topics: Acid Phosphatase; Alkaline Phosphatase; Animals; Carcinoma, Hepatocellular; Cell Fractionation; Cells, Cultured; Cycloheximide; Dactinomycin; Deoxyribonucleases; Fibroblasts; Glucuronidase; HeLa Cells; Humans; Liver; Liver Neoplasms; Mice; Neoplasms, Experimental; Rats; Ribonucleases | 1974 |
Properties of SV40 rescued from actinomycin D-sensitive and actinomycin D-resistant transformed hamster cells. I. Lytic infection.
Topics: Animals; Antigens, Neoplasm; Antigens, Viral; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Clone Cells; Cricetinae; Dactinomycin; Dextrans; DNA, Viral; Drug Resistance; Genetic Variation; Haplorhini; Hot Temperature; Kidney; Neoplasms, Experimental; Simian virus 40; Sonication; Viral Plaque Assay | 1974 |
Properties of SV 40 rescued from actinomycin D-sensitive and actinomycin D-resistant transformed hamster cells. II. Transforming capacity, oncogenicity, TSTA induction.
Topics: Animals; Antigens, Neoplasm; Cell Line; Cell Transformation, Neoplastic; Clone Cells; Cricetinae; Dactinomycin; Drug Resistance; Fluorescent Antibody Technique; Genetic Variation; Graft Rejection; Haplorhini; Histocompatibility Antigens; Kidney; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Simian virus 40; Viral Plaque Assay | 1974 |
Effect of inhibitors of nucleic acid synthesis on steroid-mediated induction of tyrosine aminotransferase in hepatoma cell cultures.
Topics: Carbon Isotopes; Culture Techniques; Cycloheximide; Cytarabine; Dactinomycin; Dexamethasone; DNA; Enzyme Induction; Mitomycins; Neoplasms, Experimental; RNA; Thymidine; Tritium; Tyrosine Transaminase; Uridine; Valine | 1967 |
Control of specific gene expression examined in synchronized mammalian cells.
Topics: Animals; Carcinoma, Hepatocellular; Culture Techniques; Cycloheximide; Dactinomycin; Dexamethasone; Enzyme Induction; Enzyme Repression; Genes, Regulator; Genetic Code; Liver Neoplasms; Mitosis; Neoplasms, Experimental; Rats; Time; Tyrosine Transaminase | 1969 |
Control of tyrosine aminotransferase synthesis in tissue culture by a factor in serum.
Topics: Blood Proteins; Carcinoma, Hepatocellular; Clone Cells; Culture Media; Dactinomycin; Dexamethasone; Enzyme Induction; Liver Neoplasms; Neoplasms, Experimental; Radioimmunoassay; Tyrosine Transaminase | 1969 |
Control of degradation and synthesis of induced tyrosine aminotransferase studied in hepatoma cells in culture.
Topics: Carcinoma, Hepatocellular; Culture Media; Culture Techniques; Cycloheximide; Dactinomycin; Enzyme Induction; Hydrocortisone; Leucine; Liver Neoplasms; Neoplasms, Experimental; Tritium; Tyrosine Transaminase | 1969 |
Dietary induction of some enzymes of amino acid metabolism following the acute administration of aminoazo dyes.
Topics: Amino Acids; Animals; Caseins; Dactinomycin; Diet; Enzyme Induction; L-Serine Dehydratase; Liver Neoplasms; Lyases; Male; Neoplasms, Experimental; p-Dimethylaminoazobenzene; Rats; Time Factors; Transaminases; Tryptophan Oxygenase; Tyrosine Transaminase | 1970 |
Tyrosine transaminase induction: differential effect of 5-azacytidine on liver and hepatoma 5123D.
Topics: Adrenalectomy; Animals; Carbon Isotopes; Carboxy-Lyases; Carcinoma, Hepatocellular; Dactinomycin; Enzyme Induction; Hindlimb; Hydrocortisone; Kinetics; Leucine; Liver; Liver Neoplasms; Macromolecular Substances; Male; Neoplasm Transplantation; Neoplasms, Experimental; Nucleosides; Ornithine; Protein Biosynthesis; Rats; Ribosomes; Sodium Chloride; Tyrosine Transaminase | 1971 |
Expression of aryl hydrocarbon hydroxylase induction and suppression of tyrosine aminotransferase induction in somatic-cell hybrids.
Topics: Animals; Antibodies; Antigen-Antibody Reactions; Benz(a)Anthracenes; Carcinoma, Hepatocellular; Cell Line; Cycloheximide; Dactinomycin; Dexamethasone; Enzyme Induction; Fibroblasts; Hybrid Cells; Karyotyping; Kinetics; Liver Neoplasms; Methods; Mice; Mixed Function Oxygenases; Neoplasms, Experimental; Rats; Tyrosine Transaminase | 1972 |
Effect of cordycepin on induction of tyrosine aminotransferase employing hepatoma cells in tissue culture.
Topics: Adenosine Monophosphate; Butyrates; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Fractionation; Cell Line; Cytidine; Dactinomycin; Deoxyadenosines; Enzyme Induction; Hydrocortisone; Insulin; Liver Neoplasms; Methods; Neoplasms, Experimental; RNA; Time Factors; Tyrosine Transaminase | 1972 |
The mechanism of the autonomy of division of ascitic tumor cells.
Topics: Animals; Carbon Radioisotopes; Carcinoma, Ehrlich Tumor; Cell Division; Cell Fractionation; Cell Membrane Permeability; Cell Transformation, Neoplastic; Dactinomycin; DNA, Neoplasm; Mice; Mice, Inbred Strains; Mitosis; Neoplasm Proteins; Neoplasm Transplantation; Neoplasms, Experimental; Potassium; Rats; Ribonucleases; Stimulation, Chemical; Subcellular Fractions; Surface-Active Agents; Thymidine; Tritium | 1974 |
ICRF-159 in treatment of germinal testicular tumor in animals.
Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Dactinomycin; Disease Models, Animal; Dogs; Drug Therapy, Combination; Fluorouracil; Male; Methotrexate; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Piperazines; Propane; Teratoma; Testicular Neoplasms; Vincristine | 1974 |
Chemotherapy and immunotherapy of three human lymphomas serially transplantable in the neonatal Syrian hamster.
Topics: Age Factors; Animals; Animals, Newborn; Antilymphocyte Serum; Cricetinae; Cyclophosphamide; Dactinomycin; Female; Immune Sera; Immunization, Passive; Leukemia, Lymphoid; Lymphocyte Transfusion; Lymphoma; Maternal-Fetal Exchange; Mercaptopurine; Methotrexate; Neoplasm Transplantation; Neoplasms, Experimental; Prednisone; Pregnancy; Spleen; Time Factors; Vincristine | 1972 |
Morphological differentiation induced by prostaglandin in mouse neuroblastoma cells in culture.
Topics: Animals; Axons; Cell Differentiation; Cell Division; Cells, Cultured; Clone Cells; Cycloheximide; Dactinomycin; Mice; Neoplasms, Experimental; Neuroblastoma; Prostaglandins; Vinblastine | 1972 |
Effect of trypsin on cell volume and mass.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Cells; Dactinomycin; DNA; Fibroblasts; Leucine; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; RNA; Thymidine; Tritium; Trypsin | 1972 |
IgM-producing tumors in the BALB-c mouse: a model for B-cell maturation.
Topics: Animals; B-Lymphocytes; Cytoplasm; Dactinomycin; Endoplasmic Reticulum; Fluorescent Antibody Technique; Fucose; Galactose; Histocytochemistry; Immunoglobulin M; Kinetics; Leucine; Lymphoma, Non-Hodgkin; Mannose; Mice; Mice, Inbred BALB C; Mitogens; Models, Biological; Neoplasms, Experimental; Tritium | 1974 |
In vitro conversion of normal mouse lymphocytes by plasmacytoma RNA to express idiotypic specificities on their surface characteristic of the plasmacytoma immunoglobulin.
Topics: Animals; Antibody Specificity; Binding Sites, Antibody; Cell Membrane; Centrifugation, Density Gradient; Cycloheximide; Dactinomycin; Deoxyribonucleases; DNA, Bacterial; Escherichia coli; Immune Adherence Reaction; Leucine; Liver; Lymphocytes; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Plasmacytoma; Pronase; Puromycin; Rabbits; Ribonucleases; RNA, Bacterial; RNA, Neoplasm; Spleen; Thymidine; Tritium; Uridine | 1974 |
Binding of cadmium ions by rat liver and kidney.
Topics: Animals; Cadmium; Carbon Isotopes; Cathepsins; Chromatography, Gel; Cycloheximide; Dactinomycin; Dialysis; Female; Kidney; Leucine; Liver; Male; Neoplasms, Experimental; Nickel; Peptide Hydrolases; Protein Binding; Protein Biosynthesis; Proteins; Radioisotopes; Rats; Rhabdomyosarcoma; Spectrophotometry, Atomic | 1972 |
Effects of inhibitors of protein and nucleic acid synthesis on the expression of H-2 and Moloney leukemia virus-determined cell-surface antigens on cultured murine lymphoma cells.
Topics: Animals; Antigens; Antigens, Neoplasm; Antigens, Viral; Antineoplastic Agents; Cell Membrane; Cells, Cultured; Culture Media; Cycloheximide; Cytarabine; Dactinomycin; Histocompatibility Antigens; Hydroxyurea; Lymphoma; Mice; Mitomycins; Moloney murine leukemia virus; Neoplasm Proteins; Neoplasms, Experimental; Puromycin; RNA, Neoplasm | 1972 |
Effects of inhibitors of energetic metabolism on RNA turnover in animal cells.
Topics: Animals; Antimetabolites; Antimycin A; Azides; Base Sequence; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Cells, Cultured; Centrifugation, Density Gradient; Cyanides; Dactinomycin; Dinitrophenols; Electrophoresis, Paper; Energy Transfer; Female; Fluorides; Iodoacetates; Kinetics; Mice; Neoplasm Proteins; Neoplasm Transplantation; Neoplasms, Experimental; Oligomycins; Ovarian Neoplasms; Phosphorus Isotopes; RNA; RNA, Neoplasm; Rotenone | 1973 |
[Expression of tumorigenic potential in isologous hybrid clones of Chinese hamster cells (author's transl)].
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Chromosome Aberrations; Chromosomes; Clone Cells; Cricetinae; Cytogenetics; Dactinomycin; Drug Resistance; Female; Hybrid Cells; Karyotyping; Male; Mitosis; Neoplasms, Experimental; Phenotype | 1973 |
Influence of hormone-secretin pituitary tumors on RNA biosynthesis in rat anterior pituitary.
Topics: Animals; Centrifugation, Density Gradient; Dactinomycin; Estradiol; Growth Hormone; Guanosine; In Vitro Techniques; Neoplasms, Experimental; Pituitary Gland; Pituitary Neoplasms; Prolactin; Rats; RNA, Neoplasm; RNA, Transfer; Time Factors; Tritium; Uridine | 1974 |
[Development and new trends in drug research].
Topics: Alcohols; Anti-Bacterial Agents; Biochemical Phenomena; Biochemistry; Bromine; Carbon Isotopes; Dactinomycin; DNA; Mannomustine; Neoplasms, Experimental; RNA; Thiotepa; Tritium | 1968 |
[Hybridization between 2 cell lines of the Chinese hamster with different tumorigenic powers].
Topics: Animals; Azaguanine; Cell Line; Cricetinae; Dactinomycin; Hybridization, Genetic; Karyotyping; Mitosis; Mutation; Neoplasms, Experimental | 1971 |
[Time factor in evaluating antineoplastic agents].
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carcinoma 256, Walker; Dactinomycin; Fluorouracil; Melphalan; Mercaptopurine; Methylthiouracil; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Neoplasms, Experimental; Nitrogen Mustard Compounds; Rats; Sarcoma, Experimental; Time Factors | 1972 |
Tumor inhibition, persistence, and binding of actinomycin D in mouse skin.
Topics: Animals; Autoradiography; Benz(a)Anthracenes; Carbon Isotopes; Chromatography, Thin Layer; Dactinomycin; Depression, Chemical; Female; Mice; Neoplasms, Experimental; Papilloma; Skin; Skin Neoplasms; Terpenes; Trichloroacetic Acid; Tritium | 1972 |
Absence of paired cisternae during mitosis in the presence of actinomycin D and puromycin.
Topics: Animals; Cell Nucleus; Cytoplasm; Dactinomycin; Endoplasmic Reticulum; Golgi Apparatus; Leukemia, Radiation-Induced; Membranes; Methods; Microscopy, Electron; Mitochondria; Mitosis; Neoplasms, Experimental; Puromycin; Rats; Rats, Inbred Strains; Ribosomes; Strontium Isotopes | 1972 |
[In vivo distribution of daunomycin, acetyl kidamycin, actinomycin D and chromomycin A3].
Topics: Animals; Antibiotics, Antineoplastic; Dactinomycin; Daunorubicin; DNA; Injections, Intravenous; Male; Mice; Neoplasms, Experimental; Rabbits; RNA | 1971 |
Studies on the origin of proteins in the nucleoli of mouse ascites tumour cells: a test for protein transfer to the nucleoli.
Topics: Adenosine Triphosphate; Amino Acids; Animals; Ascitic Fluid; Biological Transport, Active; Blood; Carbon Isotopes; Cell Line; Cell Nucleolus; Cell Nucleus; Centrifugation, Density Gradient; Culture Media; Culture Techniques; Cycloheximide; Cytoplasm; Dactinomycin; Diffusion; Dinitrophenols; Electrophoresis; Lysine; Metabolism; Mice; Microsomes; Neoplasm Proteins; Neoplasms, Experimental; RNA; Temperature; Tritium | 1971 |
RNA metabolism in mouse myeloma cells.
Topics: Animals; Carbon Isotopes; Cell Line; Cell Nucleus; Centrifugation, Density Gradient; Cycloheximide; Cytoplasm; Cytosine Nucleotides; Dactinomycin; DNA, Neoplasm; Guanine Nucleotides; Mice; Multiple Myeloma; Neoplasm Proteins; Neoplasms, Experimental; Phosphorus Isotopes; RNA, Neoplasm; RNA, Ribosomal | 1971 |
The effect of actinomycin D on the incorporation of labeled vitamin A acid in normal and tumor epithelium.
Topics: Animals; Autoradiography; Benz(a)Anthracenes; Carbon Isotopes; Cell Nucleus; Cytoplasmic Granules; Dactinomycin; Epithelium; Keratoacanthoma; Male; Microscopy, Electron; Neoplasms, Experimental; Rabbits; Skin Absorption; Skin Neoplasms; Time Factors; Vitamin A | 1971 |
[Study of the distribution of C14 dactinomycin in the body of intact mice and mice with lymphosarcoma LIO-1 and melanoma Harding-Passey].
Topics: Animals; Dactinomycin; Injections, Intravenous; Kidney; Liver; Lymphoma, Non-Hodgkin; Melanoma; Mice; Neoplasms, Experimental; Radiometry; Spleen; Time Factors | 1971 |
Inhibition of mouse skin tumorigenesis by actinomycin D.
Topics: Animals; Benz(a)Anthracenes; Croton Oil; Dactinomycin; In Vitro Techniques; Leucine; Mice; Neoplasms, Experimental; Protein Biosynthesis; Puromycin; Radiometry; Skin Neoplasms; Tritium; Urethane; Uridine | 1965 |
Actinomycin D: drug concentrations and actions in mouse tissues and tumors.
Topics: Animals; Chromatography, Paper; Dactinomycin; Female; Intestine, Small; Liver; Mice; Neoplasms, Experimental; Osteosarcoma; RNA; Salivary Glands; Spleen; Thymus Gland; Time Factors; Tritium; Uridine | 1968 |
Toxic fractions obtained from tumor isolates and related clinical implications.
Topics: Actinomycetales; Animals; Dactinomycin; Guinea Pigs; HeLa Cells; Humans; Neoplasms; Neoplasms, Experimental; Pigments, Biological; Rabbits; Toxins, Biological | 1970 |
Cytology of cultured cells surviving actinomycin D.
Topics: Culture Techniques; Dactinomycin; Fibroblasts; HeLa Cells; L Cells; Microscopy, Phase-Contrast; Mitochondria; Neoplasms, Experimental | 1967 |
Tumour cell specific differences of alkaline phosphatase.
Topics: Alkaline Phosphatase; Animals; Carcinoma, Ehrlich Tumor; Dactinomycin; Mice; Neoplasms, Experimental; Sarcoma 180; Sarcoma, Experimental | 1969 |
Selective effect of cortisol on deoxyribonuclease II activity of lymphosarcoma P1798.
Topics: Animals; Cell Line; Dactinomycin; Deoxyribonucleases; DNA, Neoplasm; Female; Hydrocortisone; Lymphoma, Non-Hodgkin; Male; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Thymidine; Tritium | 1969 |
Invasive tumors induced in rats with actinomycin D.
Topics: Animals; Antibiotics, Antineoplastic; Blood Glucose; Carcinogens; Dactinomycin; Injections, Intraperitoneal; Insulin; Male; Mesothelioma; Microscopy, Electron; Neoplasm Transplantation; Neoplasms, Experimental; Rats; Transplantation, Homologous; Tyrothricin | 1970 |
Rates of turnover of deoxythymidine kinase and of its template RNA in Novikoff hepatoma and neonatal liver.
Topics: Animals; Animals, Newborn; Ascitic Fluid; Aspartic Acid; Carbon Isotopes; Cycloheximide; Dactinomycin; Deoxyribonucleosides; Hematoma; Liver; Male; Neoplasms, Experimental; Phosphotransferases; Protein Biosynthesis; Puromycin; Rats; RNA; Templates, Genetic; Thymidine; Time Factors; Uridine | 1970 |
A malignant trophoblastic cell line: high rates of DNA synthesis measured by a rapid disc method.
Topics: Animals; Cell Count; Choriocarcinoma; Culture Techniques; Dactinomycin; DNA, Neoplasm; Female; Filtration; HeLa Cells; Methods; Microscopy, Electron; Neoplasm Proteins; Neoplasms, Experimental; Pregnancy; Rats; Thymidine; Time Factors; Tritium | 1970 |
Hybridization of actinomycin D- and amethopterin-resistant Chinese hamster cells in vitro.
Topics: Animals; Autoradiography; Cell Line; Cell Nucleus; Chromosomes; Clone Cells; Cricetinae; Culture Techniques; Dactinomycin; Female; Hybridization, Genetic; Karyotyping; Lung; Methods; Methotrexate; Neoplasm Transplantation; Neoplasms, Experimental; Pharmacogenetics; Tetrahydrofolate Dehydrogenase; Tritium | 1971 |
[Antineoplastic agent using sensitivity test inhibitory effect on biosynthesis of DNA as an index. 3. Sensitivity of human neoplastic tissue and bone marrow cells to antineoplastic agents].
Topics: Animals; Bone Marrow; Bone Marrow Cells; Carbon Isotopes; Dactinomycin; Depression, Chemical; DNA, Neoplasm; Formates; Neoplasms, Experimental; Rats; RNA, Neoplasm; Thymidine; Tritium | 1971 |
Controlling factors in urethan carcinogenesis in mice: effect of enzyme inducers and metabolic inhibitors.
Topics: Animals; Body Weight; Chlordan; Cycloheximide; Dactinomycin; Flavonoids; Hematocrit; Lung Neoplasms; Male; Methylcholanthrene; Mice; Neoplasms, Experimental; Organ Size; Phenobarbital; Phenothiazines; Proadifen; Puromycin; Urethane | 1971 |
Ribonucleic acid synthesis in two cell strains with different grades of malignancy.
Topics: Acridines; Animals; Dactinomycin; Fibrosarcoma; In Vitro Techniques; Mice; Neoplasms, Experimental; RNA, Neoplasm; Tritium; Uridine | 1967 |
Inhibition by actinomycin D of DNA synthesis and skin tumorigenesis induced by 7,12-dimethylbenz(a)anthracene.
Topics: Animals; Benz(a)Anthracenes; Dactinomycin; DNA; Mice; Neoplasms, Experimental; Skin; Skin Neoplasms; Thymidine; Tritium | 1968 |
Inhibition by actinomycin D of DNA and RNA synthesis and of skin carcinogenesis initiated by 7,12-dimethylbenz[a]anthracene or beta-propiolactone.
Topics: Animals; Benz(a)Anthracenes; Carcinogens; Carcinoma; Dactinomycin; DNA, Neoplasm; Female; Injections, Intraperitoneal; Lactones; Mice; Neoplasms, Experimental; Papilloma; RNA, Neoplasm; Skin Neoplasms; Thymidine; Tritium | 1968 |
Viruses and renal carcinoma of Rana pipiens. VI. Interrelationships of macromolecular synthesis and infectious virus production in frog virus 3-infected BHK 21/13 cells.
Topics: Adenine; Animals; Anura; Carbon Isotopes; Culture Techniques; Cycloheximide; Cytarabine; Dactinomycin; DNA; DNA, Viral; Herpesviridae; Hydroxyurea; Idoxuridine; Inclusion Bodies, Viral; Kidney Neoplasms; Leucine; Neoplasms, Experimental; Oncogenic Viruses; Protein Biosynthesis; RNA; RNA, Viral; Thymidine; Tritium; Uridine; Viral Proteins; Virus Replication | 1968 |
Cortisone inhibition of nuclear RNA polymerase of the human neoplasm, H. Emb. Rh. number 1, transplanted in rats.
Topics: Animals; Cell Nucleus; Cortisone; Cytosine Nucleotides; Dactinomycin; Deoxyribonucleases; Depression, Chemical; Humans; Mesenchymoma; Neoplasm Transplantation; Neoplasms, Experimental; Rats; Ribonucleases; RNA Nucleotidyltransferases; RNA, Neoplasm; Tritium | 1968 |
Ribosomal subunits of Landschütz ascites cells during changes in polysome distribution.
Topics: Amino Acids; Animals; Ascitic Fluid; Carbon Isotopes; Centrifugation, Density Gradient; Culture Media; Culture Techniques; Dactinomycin; Female; Liver; Male; Mice; Neoplasms, Experimental; Orotic Acid; Peritoneum; Rats; Ribosomes; Surface-Active Agents; Tritium; Ultracentrifugation; Uridine | 1968 |
Combination therapy with radiation and mithromycin or actinomycin D in a transplanted mouse glioma.
Topics: Animals; Antibiotics, Antineoplastic; Dactinomycin; Female; Glioma; Male; Mice; Neoplasm Transplantation; Neoplasms, Experimental | 1969 |
Inhibition of tumor induction in two-stage carcinogenesis on mouse skin.
Topics: Aflatoxins; Animals; Antineoplastic Agents; Benz(a)Anthracenes; Chloroquine; Cyclohexanes; Cytarabine; Dactinomycin; Ethers, Cyclic; Female; Mice; Neoplasms, Experimental; Skin Neoplasms; Uracil | 1969 |
Kinetics of cell volume changes of murine lymphoma cells subjected to different agents in vitro.
Topics: Animals; Antineoplastic Agents; Clone Cells; Colchicine; Culture Techniques; Cycloheximide; Dactinomycin; DNA Replication; Kinetics; Lymphoma; Mice; Neoplasms, Experimental; Radiation Effects; Time Factors | 1969 |
Relation of thymidine index to pulmonary tumor response in mice receiving urethan and other carcinogens.
Topics: Animals; Autoradiography; Carbamates; Carcinogens; Cytarabine; Dactinomycin; DNA; Fluorouracil; Injections, Intraperitoneal; Injections, Subcutaneous; Lung; Lung Neoplasms; Male; Mechlorethamine; Methylcholanthrene; Mice; Neoplasms, Experimental; Puromycin; Thymidine; Tritium; Urethane | 1969 |
Requirements for RNA and DNA synthesis in the transformation of mouse embryo cells by murine sarcoma virus (Moloney).
Topics: Cell Line; Cell Transformation, Neoplastic; Culture Techniques; Cytarabine; Dactinomycin; DNA; Embryo, Mammalian; Embryo, Nonmammalian; Mitomycins; Moloney murine leukemia virus; Neoplasms, Experimental; RNA; Thymidine; Tritium; Uridine; Virus Replication | 1969 |
Mechanism of induction of ovarian tumors in the mouse by 7,12-dimethylbenz[a]anthracene. V. Effect of metabolic inhibitors.
Topics: Aflatoxins; Animals; Antimetabolites; Benz(a)Anthracenes; Castration; Dactinomycin; Drug Synergism; Female; Injections, Intravenous; Injections, Subcutaneous; Metyrapone; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Ovarian Neoplasms; Transplantation, Homologous | 1969 |
Actinomycin resistance in cultured hamster cells.
Topics: Animals; Anti-Bacterial Agents; Autoradiography; Cell Division; Cell Line; Cell Membrane Permeability; Cricetinae; Culture Media; Dactinomycin; In Vitro Techniques; Neoplasms, Experimental; Time Factors; Tritium; Uridine | 1969 |
Effect of L-asparaginase (NSC-109,229) on transplantable and spontaneous tumors from mice and rats.
Topics: Animals; Asparaginase; Azaserine; Cyclophosphamide; Dactinomycin; Mercaptopurine; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Rats; Vincristine | 1969 |
Incorporation of L-[14C]leucine into the nucleoli of mouse ascites tumor cells.
Topics: Adenosine Triphosphate; Animals; Carbon Isotopes; Cell Nucleolus; Centrifugation, Density Gradient; Cycloheximide; Dactinomycin; Guanine Nucleotides; Kinetics; Leucine; Liver Neoplasms; Magnesium; Mice; Microsomes; Neoplasm Proteins; Neoplasms, Experimental; Protein Biosynthesis; Ribonucleases; RNA, Transfer; Time Factors | 1969 |
Replication and the activation of muscle differentiation.
Topics: Animals; Anti-Bacterial Agents; Circadian Rhythm; Colchicine; Dactinomycin; DNA; Male; Mice; Muscle Proteins; Muscles; Neoplasms, Experimental; Radiation Effects; Regeneration; Spleen; Testis; Thymidine | 1965 |
The effect of oophorectomy on the ribonucleic acid metabolism of a transplantable uterine tumour.
Topics: Animals; Castration; Chemistry Techniques, Analytical; Dactinomycin; Female; In Vitro Techniques; Neoplasm Proteins; Neoplasm Transplantation; Neoplasms, Experimental; Ovary; Phenylalanine; Puromycin; Rats; RNA, Neoplasm; Uridine; Uterine Neoplasms | 1965 |
The inhibition of L5178Y lymphoma cells by combinations of cortisone and actinomycin D.
Topics: Animals; Cortisone; Dactinomycin; Lymphoma; Mice; Neoplasms, Experimental | 1966 |