dactinomycin has been researched along with Colonic Neoplasms in 71 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 23 (32.39) | 18.7374 |
1990's | 27 (38.03) | 18.2507 |
2000's | 15 (21.13) | 29.6817 |
2010's | 5 (7.04) | 24.3611 |
2020's | 1 (1.41) | 2.80 |
Authors | Studies |
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Kelly, C; Kogan, Y; Sengupta, SK; Szabo, J | 1 |
Almassian, B; Blondin, J; Rosenbaum, DP; Sehgal, RK; Sengupta, SK | 1 |
Han, Z; He, J; He, Y; Tang, Y; Wan, Y; Wang, S; Zeng, D; Zeng, L; Zhao, Y | 1 |
Biyanee, A; Eberhardt, W; Haeussler, K; Nasrullah, U; Pfeilschifter, J; Wittig, I | 1 |
Chen, H; Cs-Szabo, G; Jin, D; Lin, Z; Lu, R; Sun, J; Wu, S; Zhang, YG; Zheng, Y | 1 |
Longpre, JM; Loo, G; Scott, DW | 1 |
Ahmed, N; Arango, D; Augenlicht, LH; Byun, DS; Chueh, AC; Corner, GA; Goel, S; Heerdt, BG; Houston, MA; Jhawer, M; Mariadason, JM; Murray, LB; Nasser, S; Nicholas, C; Smartt, HJ; Tögel, L; Wilson, AJ | 1 |
Dashwood, RH; Dashwood, WM; Delage, B; Ho, E; Rajendran, P; Williams, DE; Wuth, B; Yu, TW | 1 |
Vigneron, AM; Vousden, KH | 1 |
Lenzi, M; Schwartz, EL; Zhu, GH | 1 |
LANGDON, EA; OTTOMAN, RE; ROCHLIN, DB; SMART, CR | 1 |
Cordón-Cardó, C; Larriba, MJ; Muñoz, A; Ordóñez-Morán, P; Pálmer, HG; Sánchez-Carbayo, M | 1 |
Hopkins, RG; Loo, G; Powolny, A; Takahashi, K | 1 |
Evers, BM; Hu, W; Wang, Q; Wang, X | 1 |
Imamoto, E; Ishikawa, T; Kokura, S; Kuchide, M; Naito, Y; Okanoue, T; Uchiyama, K; Ueda, M; Yoshida, N; Yoshikawa, T | 1 |
Asada, H; Harada, Y; Imanishi, J; Ishii, M; Itoh, Y; Iwai, M; Kishida, T; Mazda, O; Okanoue, T; Shin-Ya, M | 1 |
Chiao, PJ; Choi, W; Feng, Y; Gerner, EW; Hamilton, SR; Proctor, L; Xia, Q; Zhang, W | 1 |
Bertin, I; Dauça, M; Domenjoud, L; Fiatte, C; Huin, C; Lesuffleur, T; Plénat, F; Pluvinet, A; Schohn, H; Touche, N | 1 |
Cliche, DO; Eshaque, B; Hopkins, MT; Jin, S; Ming, H; Sun, Z; Taylor, CA; Thai, B; Thompson, JE | 1 |
Fujimoto, N; Hayashi, Y; Inoue, K; Ohgusu, Y; Yuasa, H | 1 |
Huseby, NE; Johannessen, M; Moens, U; Pandur, S; Pankiv, S | 1 |
Büsing, CM; Kempmann, G; Kösters, W; Rethel, R | 1 |
Salmon, SE | 1 |
Cerny, EA; Jonah, MM; Macek, CM; Rahman, YE; Raphael, L; Sengupta, J; Tom, BH | 1 |
De Reuck, M; Preumont, AM; Stoffels, GL | 2 |
Kim, YS; Morita, A; Tsao, D | 1 |
Meyer, AS; Schmidt, TJ | 1 |
Hauri, HP; Naim, H; Sander, B | 1 |
Acheson, DW; Balasubramanian, KA; Donohue-Rolfe, A; Jacewicz, MS; Keusch, GT; Mobassaleh, M | 1 |
Breuer, WV; Cabantchik, ZI; Greger, R; Slotki, IN | 1 |
Ausiello, DA; Breuer, W; Cabantchik, IZ; Glickstein, H; Kartner, N; Riordan, JR | 1 |
Behrens, CH; Behrens, DL; Chen, SF; Fredericks, JR; Kirshenbaum, MR; Papp, LM; Polkus, ST; Sipple, P; Stafford, MM; Sun, JH | 1 |
Casazza, AM; Horwitz, SB; Trail, PA; Wang, L; Yang, CP | 1 |
Biscontin, G; Boiocchi, M; Gigante, M; Perin, T; Toffoli, G; Tumiotto, L | 1 |
Brandtzaeg, P; Krajci, P; Kvale, D; Taskén, K | 1 |
Hefta, LJ; Okai, Y; Paxton, RJ; Shively, JE; Takahashi, H | 1 |
Brandsch, M; Ganapathy, V; Leibach, FH; Miyamoto, Y | 1 |
Blagosklonny, MV; el-Deiry, WS; Omura, S; Wu, GS | 1 |
Gerner, EW; Ignatenko, NA | 1 |
Fabiani, R; Marchetti, C; Mastrandrea, V; Migliorati, G; Moraca, R; Morozzi, G; Nicoletti, I; Riccardi, C | 1 |
Gschwendt, M; Kittstein, W; Krammer, PH; Möller, P; Sträter, J; von Reyher, U | 1 |
Guo, YS; Houston, CW; Jin, GF; Thompson, JC; Townsend, CM | 1 |
Familari, M; Giraud, AS; Parker, LM; Tran, CP; Whitehead, RH | 1 |
Dimanche-Boitrel, MT; Hammann, A; Micheau, O; Solary, E | 1 |
Eguchi, H; Koh, YH; Park, YS; Suzuki, K; Taniguchi, N | 1 |
Chang, D; Chen, F; Ljungman, M; McKay, BC; Zhang, F | 1 |
Gawron, A; Jakubowicz-Gil, J; Pawlikowska-Pawlega, B; Rzymowska, J; Wojcierowski, J | 1 |
Baraz, L; Condiotti, R; Kotler, M; Nagler, A | 1 |
Chen, ZY; Shie, J; Tseng, C | 1 |
El-Deiry, WS; Meng, RD | 1 |
Juang, YT; Kiang, JG; Kiang, SC; Tsokos, GC | 1 |
Boiocchi, M; Toffoli, G | 1 |
Biscontin, G; Boiocchi, M; Rossi, C; Toffoli, G; Tumiotto, L; Viel, A | 1 |
Dodge, GR; Hassell, JR; Iozzo, RV; Kovalszky, I | 1 |
Chadeneau, C; Denis, MG; Lustenberger, P; Pleignet, C | 1 |
Jones, G; Tenenhouse, HS; Tomon, M | 1 |
Durr, FE; White, RJ | 1 |
Baglioni, C; Latham, K; Ruggiero, V | 1 |
Baylin, SB; Casero, RA; Celano, P; Giardiello, FM; Nelkin, BD | 1 |
Broggini, M; D'Incalci, M; Geroni, C; Giuliani, FC; Grandi, M; Ubezio, P | 1 |
Cooper, MR; Craig, JB; Jackson, DV; Muss, HB; Richards, FR; Spurr, CL; Stuart, JJ; White, DR | 1 |
Seidel, HJ | 2 |
Ernstberger, W; Goldenberg, DM; Witte, S | 1 |
Goldenberg, DM; Hartmann, G; Hindringer, B; Witte, S | 1 |
Goldenberg, DM; Hindringer, B; Witte, S | 1 |
Goldenberg, DM; Goldenberg, H | 1 |
Johnston, GS; Jones, AE | 1 |
Freckman, HA | 1 |
Fischer, DS | 1 |
1 review(s) available for dactinomycin and Colonic Neoplasms
Article | Year |
---|---|
The use of drugs in various types of cancer. 1.
Topics: Allopurinol; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Squamous Cell; Colonic Neoplasms; Cyclophosphamide; Dactinomycin; Diethylstilbestrol | 1970 |
70 other study(ies) available for dactinomycin and Colonic Neoplasms
Article | Year |
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New actinomycin D analogues as superior chemotherapeutic agents against primary and advanced colon tumors and colon xenografts in nude mice.
Topics: Animals; Antineoplastic Agents; Colonic Neoplasms; Dactinomycin; Humans; Leukemia L1210; Leukemia P388; Male; Mice; Mice, Nude; Neoplasm Transplantation; Transplantation, Heterologous; Tumor Cells, Cultured | 1988 |
Enantiomers of 7-(2,3-epoxypropoxy)actinomycin D as dual-action DNA-acting antitumor agents.
Topics: Animals; Antibiotics, Antineoplastic; Chemical Phenomena; Chemistry; Colonic Neoplasms; Dactinomycin; DNA, Neoplasm; In Vitro Techniques; Leukemia L1210; Melanoma; Mice; Stereoisomerism; Structure-Activity Relationship | 1988 |
circIFITM1/miR-802/Foxp1 Axis Participates in Proliferation and Invasion of Lovo Cells.
Topics: Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Dactinomycin; Forkhead Transcription Factors; Gene Expression Regulation, Neoplastic; Humans; MicroRNAs; Neoplasm Invasiveness; Repressor Proteins; Transcription Factors | 2022 |
Identification of TRIM25 as a Negative Regulator of Caspase-2 Expression Reveals a Novel Target for Sensitizing Colon Carcinoma Cells to Intrinsic Apoptosis.
Topics: Antineoplastic Agents; Caspase 2; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Cycloheximide; Cysteine Endopeptidases; Dactinomycin; Doxorubicin; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; HEK293 Cells; Humans; Loss of Function Mutation; Protein Stability; Sirolimus; Transcription Factors; Tripartite Motif Proteins; Ubiquitin-Protein Ligases | 2019 |
Vitamin D receptor is a novel transcriptional regulator for Axin1.
Topics: Animals; Axin Protein; beta Catenin; Binding Sites; Cell Nucleus; Colonic Neoplasms; Cycloheximide; Cytosol; Dactinomycin; Epithelium; Fibroblasts; HCT116 Cells; HT29 Cells; Humans; Inflammation; Intestinal Mucosa; Mice; Mice, Knockout; Promoter Regions, Genetic; Receptors, Calcitriol; Signal Transduction | 2017 |
Upregulation of GADD153 by butyrate: involvement of MAPK.
Topics: Adenocarcinoma; Apoptosis; Butyrates; Cell Line, Tumor; Chemoprevention; Colon; Colonic Neoplasms; Cycloheximide; Dactinomycin; DNA Damage; Extracellular Signal-Regulated MAP Kinases; Humans; Protein Kinase Inhibitors; RNA, Messenger; Signal Transduction; Transcription Factor CHOP; Up-Regulation | 2008 |
Apoptotic sensitivity of colon cancer cells to histone deacetylase inhibitors is mediated by an Sp1/Sp3-activated transcriptional program involving immediate-early gene induction.
Topics: Apoptosis; Binding Sites; Butyrates; Caco-2 Cells; Colonic Neoplasms; Dactinomycin; Gene Expression Regulation, Neoplastic; Genes, Immediate-Early; HCT116 Cells; Histone Deacetylase Inhibitors; HT29 Cells; Humans; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Promoter Regions, Genetic; Sp1 Transcription Factor; Sp3 Transcription Factor; Transcriptional Activation | 2010 |
Histone deacetylase turnover and recovery in sulforaphane-treated colon cancer cells: competing actions of 14-3-3 and Pin1 in HDAC3/SMRT corepressor complex dissociation/reassembly.
Topics: 14-3-3 Proteins; Acetylation; Anticarcinogenic Agents; Apoptosis; Caspase 3; Cell Cycle; Cell Line, Tumor; Colonic Neoplasms; Cycloheximide; Dactinomycin; Enzyme Activation; HCT116 Cells; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Isothiocyanates; Lysosomes; Models, Biological; NIMA-Interacting Peptidylprolyl Isomerase; Nuclear Receptor Co-Repressor 2; Peptidylprolyl Isomerase; Proteasome Inhibitors; Protein Binding; Sulfoxides; Thiocyanates | 2011 |
An indirect role for ASPP1 in limiting p53-dependent p21 expression and cellular senescence.
Topics: Acyltransferases; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Apoptosis Regulatory Proteins; Cell Cycle Proteins; Cell Line, Tumor; Cellular Senescence; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Dactinomycin; DNA Replication; DNA-Binding Proteins; Doxorubicin; Gene Expression Regulation; Humans; Hydroxyurea; Nuclear Proteins; Protein Serine-Threonine Kinases; Recombinant Fusion Proteins; RNA, Small Interfering; Transcription Factors; Transcription, Genetic; Tumor Protein p73; Tumor Suppressor Protein p53; Tumor Suppressor Proteins | 2012 |
The Sp1 transcription factor contributes to the tumor necrosis factor-induced expression of the angiogenic factor thymidine phosphorylase in human colon carcinoma cells.
Topics: Adenocarcinoma; Base Sequence; Colonic Neoplasms; Dactinomycin; DNA Primers; DNA Probes; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Kinetics; Mutagenesis, Site-Directed; Neovascularization, Pathologic; Polymerase Chain Reaction; RNA, Messenger; Sp1 Transcription Factor; Thymidine Phosphorylase; Transcription, Genetic; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2002 |
EARLY RESULTS OF COMBINED RADIATION AND CHEMOTHERAPY IN TREATMENT OF MALIGNANT TUMORS.
Topics: Antineoplastic Agents; Colonic Neoplasms; Dactinomycin; Fluorouracil; Humans; Lung Neoplasms; Mitomycin; Neoplasms; Pancreatic Neoplasms; Stomach Neoplasms | 1963 |
Genetic signatures of differentiation induced by 1alpha,25-dihydroxyvitamin D3 in human colon cancer cells.
Topics: Antibiotics, Antineoplastic; Anticarcinogenic Agents; Calcitriol; Cell Line, Tumor; Colonic Neoplasms; Dactinomycin; Drug Interactions; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Multigene Family; Oligonucleotide Array Sequence Analysis; Reproducibility of Results; Up-Regulation | 2003 |
Induction of GADD gene expression by phenethylisothiocyanate in human colon adenocarcinoma cells.
Topics: Acetylcysteine; Adenocarcinoma; Anticarcinogenic Agents; Antigens, Differentiation; Apoptosis; CCAAT-Enhancer-Binding Proteins; Cell Cycle Proteins; Cell Line, Tumor; Cell Size; Colonic Neoplasms; Dactinomycin; DNA Damage; GADD45 Proteins; Gene Expression Regulation; Humans; Intracellular Signaling Peptides and Proteins; Isothiocyanates; Nucleic Acid Synthesis Inhibitors; Oligonucleotide Array Sequence Analysis; Protein Phosphatase 1; Proteins; RNA, Messenger; Transcription Factor CHOP; Transcription Factors; Transcriptional Activation; Tumor Suppressor Protein p53 | 2003 |
Regulation of phorbol ester-mediated TRAF1 induction in human colon cancer cells through a PKC/RAF/ERK/NF-kappaB-dependent pathway.
Topics: Cell Line, Tumor; Colonic Neoplasms; Dactinomycin; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation, Neoplastic; Humans; Mitogen-Activated Protein Kinases; NF-kappa B; Promoter Regions, Genetic; Protein Kinase C; Proteins; Proto-Oncogene Proteins c-raf; Tetradecanoylphorbol Acetate; TNF Receptor-Associated Factor 1; Transcription, Genetic | 2004 |
Anoxia/reoxygenation down-regulates the expression of E-cadherin in human colon cancer cell lines.
Topics: Cadherins; Cell Hypoxia; Cell Line, Tumor; Colonic Neoplasms; Dactinomycin; Down-Regulation; HT29 Cells; Humans; Oxygen; Transcription, Genetic | 2004 |
Soluble TRAIL gene and actinomycin D synergistically suppressed multiple metastasis of TRAIL-resistant colon cancer in the liver.
Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Dactinomycin; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Synergism; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Humans; Liver Neoplasms; Mice; Microscopy, Fluorescence; Neoplasms, Experimental; Plasmids; Protein Synthesis Inhibitors; Solubility; TNF-Related Apoptosis-Inducing Ligand; Transfection | 2007 |
Inactivation of IkappaB contributes to transcriptional activation of spermidine/spermine N(1)-acetyltransferase.
Topics: Acetyltransferases; Antineoplastic Agents; Colonic Neoplasms; Cycloheximide; Dactinomycin; Fluorouracil; Humans; I-kappa B Proteins; Membrane Potentials; Mitochondria; Mitochondrial Membranes; NF-kappa B; NF-kappa B p50 Subunit; Promoter Regions, Genetic; Protein Biosynthesis; Protein Synthesis Inhibitors; Response Elements; Spermine; Transcription Factor RelA; Transcriptional Activation; Tumor Cells, Cultured | 2006 |
Genetic analysis of peroxisome proliferator-activated receptor gamma1 splice variants in human colorectal cell lines.
Topics: Base Sequence; Caco-2 Cells; Chromans; Chromosome Mapping; Colonic Neoplasms; Cycloheximide; Dactinomycin; Exons; HCT116 Cells; HT29 Cells; Humans; Pioglitazone; PPAR gamma; Protein Isoforms; RNA, Messenger; Thiazolidinediones; Troglitazone; Untranslated Regions | 2006 |
Eukaryotic translation initiation factor 5A induces apoptosis in colon cancer cells and associates with the nucleus in response to tumour necrosis factor alpha signalling.
Topics: Apoptosis; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Colonic Neoplasms; Dactinomycin; Eukaryotic Translation Initiation Factor 5A; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Nitroprusside; Peptide Initiation Factors; RNA-Binding Proteins; RNA, Small Interfering; Signal Transduction; Transfection; Tumor Necrosis Factor-alpha; Tumor Suppressor Protein p53 | 2007 |
Enhanced uptake of glycerol by butyrate treatment in HCT-15 human colon cancer cell line.
Topics: Biological Transport, Active; Butyrates; Cell Line, Tumor; Colonic Neoplasms; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Ethylene Glycol; Glycerol; Glycols; Humans; Kinetics; Propylene Glycol; Sodium; Time Factors | 2007 |
Gamma-glutamyltransferase is upregulated after oxidative stress through the Ras signal transduction pathway in rat colon carcinoma cells.
Topics: Animals; Caffeine; Carcinoma; Cell Line, Tumor; Colonic Neoplasms; Cycloheximide; Dactinomycin; gamma-Glutamylcyclotransferase; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Oxidative Stress; ras Proteins; Rats; RNA, Messenger; Signal Transduction; Vitamin K 3 | 2007 |
[A rare form of Kaposi's sarcoma with intestinal symptoms (author's transl)].
Topics: Adult; Colon; Colonic Neoplasms; Cyclophosphamide; Dactinomycin; Humans; Intestinal Neoplasms; Intestine, Small; Male; Sarcoma, Kaposi; Vincristine | 1980 |
Human tumor colony assay and chemosensitivity testing.
Topics: Antineoplastic Agents; Cell Line; Cell Survival; Clone Cells; Colonic Neoplasms; Dactinomycin; Drug Evaluation; Drug Evaluation, Preclinical; Humans; Melanoma | 1984 |
Liposome uptake into human colon adenocarcinoma cells in monolayer, spinner, and trypsinized cultures.
Topics: Adenocarcinoma; Biological Transport; Cell Line; Colonic Neoplasms; Dactinomycin; DNA Replication; Humans; Kinetics; Lipid Bilayers; Phosphatidylcholines; Protein Biosynthesis; Transcription, Genetic; Trypsin | 1983 |
[Detection of precancerous lesions of stomach and intestine].
Topics: Colon; Colonic Neoplasms; Dactinomycin; Humans; Precancerous Conditions; Stomach; Stomach Neoplasms | 1983 |
Nuclear size and nuclear binding of tritiated actinomycin D into epithelial cells of colon cancer patients with apparently normal colorectal mucosa.
Topics: Autoradiography; Biopsy; Cell Differentiation; Cell Nucleus; Chromatin; Colon; Colonic Neoplasms; Dactinomycin; Epithelium; Histological Techniques; Humans; Intestinal Mucosa | 1981 |
Effect of sodium butyrate on alkaline phosphatase in HRT-18, a human rectal cancer cell line.
Topics: Alkaline Phosphatase; Butyrates; Butyric Acid; Cell Line; Colonic Neoplasms; Cycloheximide; Dactinomycin; Enzyme Induction; Humans; Kinetics | 1982 |
Potential mechanisms underlying autoregulation of glucocorticoid receptor mRNA levels in the DHD/K12/PROb rat colonic adenocarcinoma cell line.
Topics: Adenocarcinoma; Androstanols; Animals; Blotting, Western; Cell Line; Colonic Neoplasms; Culture Techniques; Cycloheximide; Dactinomycin; Epithelium; Gene Expression Regulation, Neoplastic; Half-Life; Homeostasis; Kinetics; Protein Synthesis Inhibitors; Rats; Receptors, Glucocorticoid; RNA, Messenger; Time Factors; Tumor Cells, Cultured | 1995 |
Induction of lactase biosynthesis in the human intestinal epithelial cell line Caco-2.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adenocarcinoma; beta-Galactosidase; Bucladesine; Cell Line; Colforsin; Colonic Neoplasms; Cyclic AMP; Dactinomycin; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Epithelium; Humans; Lactase; Lactase-Phlorizin Hydrolase; Methionine; Microvilli; Sucrase-Isomaltase Complex; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Maturational regulation of globotriaosylceramide, the Shiga-like toxin 1 receptor, in cultured human gut epithelial cells.
Topics: Adenocarcinoma; Bacterial Toxins; Butyrates; Butyric Acid; Cell Line; Cell Survival; Colonic Neoplasms; Cycloheximide; Dactinomycin; Enterotoxins; Epithelium; Flow Cytometry; Gene Expression Regulation, Neoplastic; Glycolipids; Humans; Kinetics; Receptors, Cell Surface; Shiga Toxin 1; Time Factors; Transcription, Genetic; Trihexosylceramides; Tumor Cells, Cultured | 1995 |
Long-term cAMP activation of Na(+)-K(+)-2Cl- cotransporter activity in HT-29 human adenocarcinoma cells.
Topics: Adenocarcinoma; Bumetanide; Carrier Proteins; Chlorides; Colforsin; Colonic Neoplasms; Cyclic AMP; Cycloheximide; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Dactinomycin; Humans; Kinetics; Membrane Proteins; Potassium; Protein Biosynthesis; Sodium; Sodium-Potassium-Chloride Symporters; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1993 |
Protein kinase C mediates down-regulation of cystic fibrosis transmembrane conductance regulator levels in epithelial cells.
Topics: Adenocarcinoma; Colonic Neoplasms; Cycloheximide; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Dactinomycin; Epithelium; Gene Expression Regulation, Neoplastic; Humans; Indoles; Maleimides; Membrane Proteins; Pancreatic Neoplasms; Protein Biosynthesis; Protein Kinase C; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1993 |
(R,R)-2,2'-[1,2-ethanediylbis[imino(1-methyl-2,1-ethanediyl)]]- bis[5-nitro-1H-benz[de]isoquinoline-1,3-(2H)-dione] dimethanesulfonate (DMP 840), a novel bis-naphthalimide with potent nonselective tumoricidal activity in vitro.
Topics: Amsacrine; Animals; Antineoplastic Agents; Cell Division; Clinical Trials, Phase I as Topic; Colonic Neoplasms; Dactinomycin; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance; Drug Screening Assays, Antitumor; Humans; Isoquinolines; KB Cells; Kinetics; Leucine; Leukemia L1210; Leukemia P388; Mammary Neoplasms, Experimental; Melanoma; Melanoma, Experimental; Mesylates; Mice; Mitoxantrone; Thymidine; Transplantation, Heterologous; Tumor Cells, Cultured; Uridine | 1994 |
Reversal of the human and murine multidrug-resistance phenotype with megestrol acetate.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma; Chemotherapy, Adjuvant; Colonic Neoplasms; Dactinomycin; Doxorubicin; Drug Resistance; Drug Screening Assays, Antitumor; Female; Flow Cytometry; Humans; Mammary Neoplasms, Experimental; Megestrol; Megestrol Acetate; Mice; Mice, Nude; Neoplasm Transplantation; Phenotype; Transplantation, Heterologous; Tumor Cells, Cultured | 1994 |
Doxorubicin, vincristine, and actinomycin-D, but not teniposide, require long-lasting uninterrupted verapamil pressure to overcome drug resistance in multidrug-resistant cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Colonic Neoplasms; Dactinomycin; Doxorubicin; Drug Resistance; Humans; Teniposide; Tumor Cells, Cultured; Verapamil; Vincristine | 1993 |
Interferon-gamma stimulation of messenger RNA for human secretory component (poly-Ig receptor) depends on continuous intermediate protein synthesis.
Topics: Colonic Neoplasms; Cycloheximide; Dactinomycin; Dichlororibofuranosylbenzimidazole; Humans; Interferon-gamma; RNA, Messenger; Secretory Component; Time Factors; Tumor Cells, Cultured; Up-Regulation | 1993 |
Differential regulation of carcinoembryonic antigen and biliary glycoprotein by gamma-interferon.
Topics: Antigens, CD; Antigens, Neoplasm; Base Sequence; Carcinoembryonic Antigen; Cell Adhesion Molecules; Colonic Neoplasms; Cycloheximide; Dactinomycin; Female; Gene Expression Regulation, Neoplastic; Glycoproteins; Humans; Interferon-gamma; Membrane Glycoproteins; Molecular Sequence Data; RNA, Messenger; Tumor Cells, Cultured | 1993 |
Regulation of taurine transport in human colon carcinoma cell lines (HT-29 and Caco-2) by protein kinase C.
Topics: Biological Transport; Colchicine; Colonic Neoplasms; Cycloheximide; Cytochalasin D; Dactinomycin; Humans; Kinetics; Protein Kinase C; Taurine; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured | 1993 |
Proteasome-dependent regulation of p21WAF1/CIP1 expression.
Topics: Acetylcysteine; Cell Line; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cycloheximide; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dactinomycin; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Humans; Kinetics; Luciferases; Multienzyme Complexes; Promoter Regions, Genetic; Proteasome Endopeptidase Complex; Protein Biosynthesis; Recombinant Proteins; Transcription, Genetic; Transfection; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 1996 |
Growth arrest- and polyamine-dependent expression of spermidine/spermine N1-acetyltransferase in human tumor cells.
Topics: Acetyltransferases; Blotting, Northern; Cell Division; Colonic Neoplasms; Dactinomycin; Eflornithine; Enzyme Induction; Enzyme Repression; Heat-Shock Response; Humans; Polyamines; Putrescine; RNA; Spermidine; Spermine; Tumor Cells, Cultured | 1996 |
Deoxycholic acid and SCFA-induced apoptosis in the human tumor cell-line HT-29 and possible mechanisms.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Apoptosis; Butyrates; Butyric Acid; Calcium; Chelating Agents; Colonic Neoplasms; Cycloheximide; Dactinomycin; Deoxycholic Acid; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Inhibitors; Genistein; Humans; Isoflavones; Propionates; Protein Synthesis Inhibitors; Time Factors; Tumor Cells, Cultured | 1997 |
Colon carcinoma cells use different mechanisms to escape CD95-mediated apoptosis.
Topics: Antigens, Neoplasm; Apoptosis; Brefeldin A; Carcinoma; Cell Transformation, Neoplastic; Colonic Neoplasms; Cycloheximide; Cyclopentanes; Dactinomycin; Enzyme Inhibitors; Fas Ligand Protein; fas Receptor; Humans; Immunologic Capping; Interferon-gamma; Intestinal Mucosa; Membrane Glycoproteins; Nucleic Acid Synthesis Inhibitors; Phorbol Esters; Protein Kinase C; Protein Synthesis Inhibitors; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1998 |
Insulin-like growth factor-I promotes multidrug resistance in MCLM colon cancer cells.
Topics: Animals; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Survival; Colonic Neoplasms; Dactinomycin; Doxorubicin; Drug Resistance, Multiple; Gene Expression Regulation; Genes, MDR; Genes, ras; Insulin-Like Growth Factor I; Lovastatin; Mice; Mitochondria; RNA, Messenger; Superoxide Dismutase; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1998 |
Short-chain fatty acids inhibit intestinal trefoil factor gene expression in colon cancer cells.
Topics: Acetates; Alkaline Phosphatase; Animals; Base Sequence; Butyrates; Cell Differentiation; Cell Line; Colonic Neoplasms; Consensus Sequence; Dactinomycin; DNA Primers; DNA Probes; Gene Expression Regulation, Neoplastic; Growth Substances; Humans; Intestinal Mucosa; Kinetics; Mice; Mucins; Muscle Proteins; Neuropeptides; Peptides; Polymerase Chain Reaction; Promoter Regions, Genetic; Propionates; RNA, Messenger; Sequence Alignment; Sequence Homology, Nucleic Acid; Transcription, Genetic; Trefoil Factor-2; Trefoil Factor-3; Tumor Cells, Cultured | 1998 |
STAT-1-independent upregulation of FADD and procaspase-3 and -8 in cancer cells treated with cytotoxic drugs.
Topics: Adaptor Proteins, Signal Transducing; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Carrier Proteins; Caspase 2; Caspase 3; Caspase 8; Caspase 9; Caspases; Cisplatin; Colonic Neoplasms; Dactinomycin; DNA-Binding Proteins; Doxorubicin; Enzyme Precursors; fas Receptor; Fas-Associated Death Domain Protein; Gene Expression Regulation, Neoplastic; Humans; Isoenzymes; Mitomycin; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Receptors, Tumor Necrosis Factor; RNA, Messenger; STAT1 Transcription Factor; Trans-Activators; Transcription, Genetic; Tumor Cells, Cultured; Up-Regulation | 1999 |
Acceleration of adhesion of cancer cells and neutrophils to endothelial cells in the absence of de novo protein synthesis: possible implication for involvement of hydroxyl radicals.
Topics: Catalase; Cell Adhesion; Cell Membrane; Chelating Agents; Colonic Neoplasms; Cycloheximide; Dactinomycin; Edetic Acid; Endothelium, Vascular; Humans; Hydrogen Peroxide; Hydroxyl Radical; Hypoxanthine; Neutrophils; Nitrates; Protein Biosynthesis; Reactive Oxygen Species; Superoxide Dismutase; Tumor Cells, Cultured; Xanthine Oxidase | 1999 |
Dose-dependent effects of DNA-damaging agents on p53-mediated cell cycle arrest.
Topics: Blotting, Western; Bromodeoxyuridine; Cell Cycle; Colonic Neoplasms; Cyclin E; Dactinomycin; DNA Damage; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Flow Cytometry; G1 Phase; Humans; Infrared Rays; Models, Biological; Oncogene Proteins, Viral; Repressor Proteins; RNA, Messenger; Time Factors; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Ultraviolet Rays | 1999 |
The effect of quercetin on induction of apoptosis.
Topics: Adenocarcinoma; Animals; Apoptosis; Colonic Neoplasms; Dactinomycin; Fluorescent Dyes; Haplorhini; Heat-Shock Response; Kidney; Quercetin; Tumor Cells, Cultured | 1999 |
Sensitization of resting T cells to autologous natural-killer-cell-mediated lysis by phytohemagglutinin.
Topics: Adenocarcinoma; Colonic Neoplasms; Concanavalin A; Cycloheximide; Cytotoxicity, Immunologic; Dactinomycin; DNA Replication; Humans; Interleukin-2; K562 Cells; Killer Cells, Natural; Lymphocyte Activation; Mitomycin; Nucleic Acid Synthesis Inhibitors; Phytohemagglutinins; Protein Biosynthesis; Protein Synthesis Inhibitors; RNA; T-Lymphocyte Subsets; Tumor Cells, Cultured | 1999 |
Up-regulation of gut-enriched krüppel-like factor by interferon-gamma in human colon carcinoma cells.
Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Division; Colonic Neoplasms; Dactinomycin; DNA-Binding Proteins; Dose-Response Relationship, Drug; Humans; Interferon-gamma; Kinetics; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Protein Biosynthesis; RNA, Messenger; Substrate Specificity; Transcription Factors; Transfection; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Up-Regulation | 2000 |
p53-independent upregulation of KILLER/DR5 TRAIL receptor expression by glucocorticoids and interferon-gamma.
Topics: Antibiotics, Antineoplastic; Apoptosis; Betulinic Acid; Colonic Neoplasms; Dactinomycin; Dexamethasone; DNA-Binding Proteins; Female; Glioblastoma; Glucocorticoids; Humans; Interferon-gamma; Melanoma; Mutation; Naphthoquinones; Ovarian Neoplasms; Pentacyclic Triterpenes; Prednisolone; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor; RNA, Messenger; STAT1 Transcription Factor; Trans-Activators; Triterpenes; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Up-Regulation | 2001 |
N(omega)-nitro-L-arginine inhibits inducible HSP-70 via Ca(2+), PKC, and PKA in human intestinal epithelial T84 cells.
Topics: Calcium; Cell Nucleus; Chelating Agents; Colonic Neoplasms; Cyclic AMP-Dependent Protein Kinases; Cycloheximide; Cytosol; Dactinomycin; DNA-Binding Proteins; Egtazic Acid; Enzyme Inhibitors; Guanidines; Heat Shock Transcription Factors; Hot Temperature; HSP70 Heat-Shock Proteins; Humans; Indoles; Intestinal Mucosa; Intestines; Isoquinolines; Maleimides; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Protein Kinase C; Protein Kinases; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfonamides; Transcription Factors; Tumor Cells, Cultured | 2002 |
Mechanism of multidrug resistance in human tumour cell lines and complete reversion of cellular resistance.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Carcinoma; Cisplatin; Colonic Neoplasms; Dactinomycin; Doxorubicin; Drug Resistance; Gene Expression; Humans; Membrane Glycoproteins; Neoplasm Proteins; Phenotype; RNA, Messenger; Tumor Cells, Cultured; Vincristine | 1992 |
Pleiotropic-resistant phenotype is a multifactorial phenomenon in human colon carcinoma cell lines.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Division; Cell Membrane; Cisplatin; Colonic Neoplasms; Dactinomycin; Doxorubicin; Drug Resistance; Extracellular Space; Gene Expression; Humans; Intracellular Fluid; Kinetics; Membrane Glycoproteins; Phenotype; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured; Vincristine | 1991 |
Transforming growth factor beta alters the expression of heparan sulfate proteoglycan in human colon carcinoma cells.
Topics: Cell Line; Cell Nucleus; Chondroitin Sulfate Proteoglycans; Colonic Neoplasms; Cycloheximide; Cysteine; Dactinomycin; Heparan Sulfate Proteoglycans; Heparitin Sulfate; Humans; Kinetics; Molecular Weight; Poly A; RNA; RNA, Messenger; RNA, Neoplasm; Transcription, Genetic; Transforming Growth Factor beta | 1990 |
A secreted Mr approximately 40,000 glycoprotein specifically induced by glucocorticoids in a rat colon carcinoma cell line.
Topics: Adenocarcinoma; Animals; Cell Line; Chromatography, Affinity; Chromatography, High Pressure Liquid; Colonic Neoplasms; Dactinomycin; Dexamethasone; Electrophoresis, Polyacrylamide Gel; Glycoproteins; Kinetics; Molecular Weight; Rats | 1991 |
Expression of 25-hydroxyvitamin D3-24-hydroxylase activity in Caco-2 cells. An in vitro model of intestinal vitamin D catabolism.
Topics: Adenocarcinoma; Amanitins; Calcifediol; Calcitriol; Colonic Neoplasms; Cycloheximide; Cytochrome P-450 Enzyme System; Dactinomycin; Enzyme Induction; Fibroblasts; Humans; Hydroxylation; Intestines; Kinetics; Steroid Hydroxylases; Tumor Cells, Cultured; Vitamin D; Vitamin D3 24-Hydroxylase | 1990 |
Development of mitoxantrone.
Topics: Animals; Anthraquinones; Antineoplastic Agents; Cell Line; Chemistry, Pharmaceutical; Colonic Neoplasms; Cricetinae; Cricetulus; Dactinomycin; DNA; Doxorubicin; Drug Evaluation; Drug Synergism; Female; Heart; Humans; Intercalating Agents; Interphase; Leukemia L1210; Leukemia P388; Melanoma; Mice; Mitoxantrone; RNA; RNA, Double-Stranded; Structure-Activity Relationship | 1985 |
Cytostatic and cytotoxic activity of tumor necrosis factor on human cancer cells.
Topics: Breast Neoplasms; Cell Division; Cell Line; Cell Survival; Colonic Neoplasms; Cycloheximide; Cytotoxins; Dactinomycin; Female; Glycoproteins; Humans; Interferon-gamma; Melanoma; Neoplasm Proteins; Receptors, Cell Surface; Receptors, Tumor Necrosis Factor; Recombinant Proteins; Tumor Necrosis Factor-alpha; Uterine Cervical Neoplasms | 1987 |
Effect of polyamine depletion on c-myc expression in human colon carcinoma cells.
Topics: Actins; Cell Cycle; Cell Division; Colonic Neoplasms; Dactinomycin; Eflornithine; Gene Expression Regulation; Half-Life; Histones; Humans; Ornithine Decarboxylase; Polyamines; Proto-Oncogenes; RNA, Messenger; Spermidine; Spermine; Tumor Cells, Cultured | 1988 |
Intracellular doxorubicin concentrations and drug-induced DNA damage in a human colon adenocarcinoma cell line and in a drug-resistant subline.
Topics: Adenocarcinoma; Cell Line; Cell Survival; Cisplatin; Colonic Neoplasms; Cytarabine; Dactinomycin; DNA Damage; DNA, Neoplasm; Doxorubicin; Drug Resistance; Flow Cytometry; Humans; Verapamil | 1988 |
Treatment of advanced colorectal carcinoma with actinomycin D, vincristine, methyl-CCNU, and methotrexate.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Colonic Neoplasms; Dactinomycin; Female; Humans; Male; Methotrexate; Middle Aged; Rectal Neoplasms; Semustine; Vincristine | 1987 |
[Estimation of tumor sensitivity in vitro. II. Studies with the solid Ehrlich carcinoma of the mouse and the GW 77, a heterotransplanted human carcinoma].
Topics: Animals; Antibiotics, Antineoplastic; Autoradiography; Carcinoma; Carcinoma, Ehrlich Tumor; Colonic Neoplasms; Cricetinae; Culture Media; Cytarabine; Dactinomycin; DNA, Neoplasm; Humans; Hydroxyurea; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Nucleosides; RNA, Neoplasm; Thymidine; Triaziquone; Tritium; Uridine | 1970 |
[Growth and chemotherapy of human colonic tumor-GW 77-after heterotransplantation to the thigh muscle of the hamster. Comparison with 2 transplanted tumors in animals].
Topics: Animals; Carcinoma, Ehrlich Tumor; Colonic Neoplasms; Cricetinae; Cyclophosphamide; Dactinomycin; Muscles; Neoplasm Transplantation; Sarcoma, Experimental; Thigh; Transplantation, Heterologous; Triaziquone | 1971 |
Tumour glucose-6-phosphate dehydrogenase inhibition by actinomycin.
Topics: Animals; Colonic Neoplasms; Cricetinae; Dactinomycin; Glucosephosphate Dehydrogenase; Liver; Neoplasm Transplantation; Neoplasms, Experimental | 1967 |
[On the experimental chemotherapy of a human adenocarcinoma in the cheek pouch of the Golden hamster: the effect of actinomycin C].
Topics: Adenocarcinoma; Animals; Colonic Neoplasms; Cricetinae; Dactinomycin; Humans; Mathematics; Neoplasm Transplantation; Neoplasms, Experimental | 1966 |
[Method and results of experimental chemotherapy of a human colonic carcinoma (H.Ad.No. 1) in the cheek pouch of the golden hamster].
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Aziridines; Cheek; Colonic Neoplasms; Cricetinae; Cyclophosphamide; Dactinomycin; Fluorouracil; Hydrazines; Methods; Methotrexate; Neoplasm Transplantation; Triaziquone | 1969 |
[Enzyme variations in tumors following carcinostatic therapy of human colonic tumors in golden hamsters].
Topics: Adenocarcinoma; Animals; Cheek; Colonic Neoplasms; Cricetinae; Cyclophosphamide; Dactinomycin; Female; Glucosephosphate Dehydrogenase; Glycolysis; Humans; Injections, Intraperitoneal; L-Lactate Dehydrogenase; Liver; Male; Neoplasm Transplantation; Neoplasms, Experimental; Pentoses; RNA | 1969 |
Sequential liver scanning.
Topics: Adult; Breast Neoplasms; Chloroquine; Colonic Neoplasms; Dactinomycin; Emetine; Estrogens; Female; Fluorouracil; Gold Colloid, Radioactive; Humans; Liver Abscess, Amebic; Liver Neoplasms; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Radionuclide Imaging; Thiotepa | 1969 |
Chemotherapy for metastatic colorectal liver carcinoma by intra-aortic infusion.
Topics: Antineoplastic Agents; Aorta, Abdominal; Chemotherapy, Cancer, Regional Perfusion; Colonic Neoplasms; Cyclophosphamide; Dactinomycin; Female; Fluorouracil; Humans; Injections, Intra-Arterial; Liver Neoplasms; Male; Methotrexate; Neoplasm Metastasis; Rectal Neoplasms; Remission, Spontaneous; Retrospective Studies; Time Factors; Vinblastine; Vincristine | 1971 |