dactinomycin has been researched along with Carcinoma, Hepatocellular in 195 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 143 (73.33) | 18.7374 |
| 1990's | 26 (13.33) | 18.2507 |
| 2000's | 24 (12.31) | 29.6817 |
| 2010's | 2 (1.03) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, CY; Chen, YJ; Hwang, JF; Kuo, YH; Prakash, CV; Shen, YC | 1 |
| Li, C; Li, H; Li, S; Lv, Y; Mei, Q; Wang, H; Wang, Y; Xia, C | 1 |
| Drzewoski, J; Kasznicki, J; Marczak, A; Rogalska, A; Sliwinska, A | 1 |
| Jia, L; Wang, S; Wang, X; Zhang, J; Zhou, H | 1 |
| Anwar-Mohamed, A; El-Kadi, AO | 1 |
| Rajeswari, MR; Singhal, G | 1 |
| Cao, EH; Liang, XQ; Liu, XM; Song, Y; Tang, RJ; Xiong, XF | 1 |
| Chiloeches, A; Cuevas, EP; Escribano, O; Fernández-Moreno, MD; Guijarro, LG; Hernández-Breijo, B; Martínez-Botas, J; Monserrat, J; Román, ID; Sánchez, MG; Sánchez-Alonso, V | 1 |
| Brenner, DA; Kim, YS; Lemasters, JJ; Qian, T; Schwabe, RF | 1 |
| Deguchi, M; Fujikawa, K; Inoue, H; Kawakita, T; Murata, K; Nakano, T; Ohmori, S; Okano, H; Sakai, T; Shiraki, K; Sugimoto, K; Yamanaka, T | 1 |
| BRITTAIN, RS; HERMANN, G; MARCHIORO, TL; STARZL, TE; VONKAULLA, KN; WADDELL, WR | 1 |
| DYER, HM; GULLINO, PM; MORRIS, HP | 1 |
| ZBARSKY, SH | 1 |
| ROTH, JS | 1 |
| JOLLEYS, A | 1 |
| FUKUI, N; HASEGAWA, S; MIURA, Y; MORIYAMA, Y | 1 |
| Bührer, C; Fujita, J; Kirschner, R; Koehne, P; Moderegger, E; Seeger, K; Wellmann, S; Zelmer, A | 1 |
| Christian, K; Lang, M; Maurel, P; Raffalli-Mathieu, F | 1 |
| Abe, Y; Akahane, K; Higure, A; Ikematsu, S; Itoh, H; Kikuchi, M; Muramatsu, T; Ohuchida, T; Okamoto, K; Todoroki, H | 1 |
| Barbieri, S; Chillà, A; Derenzini, M; Govoni, M; Mazzini, G; Montanaro, L; Tosti, E; Treré, D; Vici, M | 1 |
| Fujita, T; Tanaka, K; Yamamoto, A | 1 |
| Cheng, SC; Xie, Y; Zhou, J | 1 |
| El-Kadi, AO; Korashy, HM | 1 |
| Yeh, CT; Yen, GC | 1 |
| Bass, SE; Ciolino, HP; MacDonald, CJ; Memon, OS; Yeh, GC | 1 |
| Balakrishnan, K; De Maio, A | 1 |
| Furutani, T; Hara, Y; Hidaka, I; Hino, K; Korenaga, M; Lemon, SM; Li, K; Okita, K; Okuda, M; Weinman, SA; Yamaguchi, Y | 1 |
| Bogdanová, K; Cervenková, K; Poczatková, H; Riegrová, D; Rypka, M; Uherková, L; Veselý, J | 1 |
| Block, C; Diesterhaft, M; Granner, D; Hargrove, J; Noguchi, T; Olson, P; Seifert, S | 1 |
| Ohanian, SH; Schlager, SI | 1 |
| DiSorbo, DM; Litwack, G; Moriarity, DM; Savage, CR | 1 |
| Siegel, MM; Siegel, SE; Stanley, P; Weinblatt, ME; Weitzman, JJ | 1 |
| Deeley, RG; Wilson, GM | 1 |
| Carr, BI; Inagaki, M; Wang, Z | 1 |
| Fujita, H; Fukuda, Y; Kappas, A; Mitani, K; Sassa, S | 1 |
| DeBeer, FC; DeBeer, MC; Rogers, JT; Steel, DM; Whitehead, AS | 1 |
| Florén, CH; Liao, W | 1 |
| Bock, KW; Gohl, G; Lehmköster, T; Münzel, PA; Schrenk, D; Viebahn, R | 1 |
| Auwerx, J; Fruchart, JC; Saladin, R; Staels, B; Vu-Dac, N | 1 |
| Kato, M; Suzuki, A | 1 |
| Alvarez, L; Gil, B; Mato, JM; Pajares, MA | 1 |
| Martini, G; Parrella, A; Rosa, G; Salzano, S; Ursini, MV | 1 |
| Dudich, EI; Dudich, IV; Semenkova, LN | 1 |
| Dupriez, VJ; Rousseau, GG | 1 |
| Abe, K; Goto, D; Kuwano, M; Okimoto, T; Ono, M; Shimotsu, H; Tsujita, Y | 1 |
| Buendia, B; Courvalin, JC; Duband-Goulet, I | 1 |
| Hayashi, Y; Koike, K; Shimazu, T; Takada, S; Ueno, Y | 1 |
| Fung, M; Minta, JO; Paramaswara, B | 1 |
| Fung, M; Minta, J | 1 |
| Fujikawa, K; Ito, M; Ito, T; Moriyama, M; Nakano, T; Shiraki, K; Sugimoto, K; Suzuki, A; Takase, K; Yamanaka, T | 1 |
| Cheng, SC; Luo, D; Xie, Y; Zhou, J | 1 |
| Hoshino, T; Ishizaki, K; Ohgiya, S; Ohsaka, Y | 1 |
| Ho, JW; Leung, YK | 1 |
| Kenney, FT; Lee, KL; Stiles, CD | 2 |
| Cannelakis, ZN; Theoharides, TC | 1 |
| Borsos, T; Boyle, MD; Ohanian, SH | 1 |
| Borsos, T; Ohanian, SH; Segerling, M | 3 |
| Grimm, J; Manchester, KL | 1 |
| Busch, H; Busch, RK; Daskal, Y; Merski, J; Smetana, K | 1 |
| Beliaeva, ID; Nefelova, MV; Prokopenko, VM | 1 |
| Borek, E; Mays, LL; Sharma, OK | 1 |
| Aczel, J; Enesco, HE | 2 |
| Ballard, FJ; Gunn, JM; Hanson, RW; Reshef, L; Tilghman, SM | 1 |
| Elias-Bishko, S; Epstein, D; Hershko, A | 1 |
| Bast, RC; Borsos, T; Greene, SL; Ohanian, SH; Rapp, HJ; Segerling, M; Zbar, B | 1 |
| Canellakis, ES; Fong, WF; Heller, JS | 1 |
| Canellakis, ZN; Theoharides, TC | 1 |
| Lyons, RT; Pitot, HC | 1 |
| Hayashi, H; Ishihara, H; Ishimaru, Y; Kudo, K | 1 |
| Roth, JJ; Roth, JS | 1 |
| Gaitskhoki, VS; Kisselev, OI; Pozharisski, KM; Shalumovich, WN; Shaposhnikov, JD | 1 |
| Pitot, HC | 2 |
| Borsos, T; Boyle, MD; Ohanian, SH; Schlager, SI | 1 |
| Mamont, PS; McCann, PP; Tardif, C | 1 |
| Brucksch, KP; Schmidt, CG; Seeber, B; Seeber, S | 1 |
| Duchesne, MC; Mamont, PS; McCann, PP; Tardif, C | 1 |
| Arbuzov, VA | 1 |
| Cronenberger, JH; Magee, WE; Thor, DE | 1 |
| Murty, CN; Sidransky, H; Verney, E | 1 |
| Ringold, GM; Shank, PR; Yamamoto, KR | 1 |
| Piessens, WF; Sharma, SD | 1 |
| Little, JB; Robertson, JB; Williams, JR | 1 |
| Levinson, BB; Steinberg, RA; Tomkins, GM | 1 |
| Chou, CK; Hsu, SL; Lin, YF | 1 |
| Abraham, NG; Brown, AC; da Silva, JL; Levere, RD; Lutton, JD; Moqattash, S | 1 |
| Hug, V; Levy, JR | 1 |
| Fujita, H; Kappas, A; Mitani, K; Sassa, S | 2 |
| Fiers, W; Libert, C; Van Bladel, S | 1 |
| Takekoshi, H | 2 |
| Nishimura, T; Suzuki, H; Tomida, A | 1 |
| Knowles, AF; Murray, SL | 1 |
| Crabb, DW; Qulali, M; Ross, RA; Wolfla, CE | 1 |
| Gedamu, L; Sadhu, C | 1 |
| Fujiki, H; Moore, RE; Uchida, T; Yoneda, Y | 1 |
| Imashuku, S; Ogita, S; Sawada, T; Takahashi, T; Tokiwa, K | 1 |
| Kenney, FT; Lee, KL | 2 |
| Kanamoto, Y | 1 |
| Cheng, CC; Zee-Cheng, KY | 1 |
| Cavia, E; Webb, TE | 1 |
| Martin, DW; Owen, NT | 1 |
| Martin, TE; McCarthy, BJ | 1 |
| Danko, IM; Korotkoruchko, VP | 1 |
| Miyaki, M; Moroashi, S; Ono, T | 1 |
| Pitot, HC; Weiss, JW | 1 |
| Cohen, H; Kulka, RG | 1 |
| Baxter, JD; Higgins, SJ; Rousseau, GG; Tomkins, GM | 1 |
| Boctor, A; Grossman, A | 1 |
| Fritz, JE; Kenney, FT; Lee, KL; Stiles, CD | 1 |
| Lippman, ME; Thompson, EB; Yang, SS | 1 |
| Barker, KL; Kenney, FT; Lee, KL | 1 |
| Granner, D; Sellers, L | 1 |
| Emanuel, JR; Gelehrter, TD | 1 |
| Barnett, CA; McKibbin, JB; Wicks, WD | 1 |
| McKibbin, JB; van Wijk, R; Wicks, WD | 1 |
| Becker, JE; Bushnell, DE; Potter, VR | 1 |
| Hogan, BL; McIlhinney, A; Murden, S | 1 |
| Becker, JE; Bushnell, DE; Potter, VR; Yager, JD | 1 |
| Gelboin, HV; Miller, H; Whitlock, JP | 1 |
| Garwin, JL; Gelehrter, TD | 1 |
| Plagemann, PG | 3 |
| Falkson, G; Geddes, EW | 1 |
| Bancroft, FC; Goldlust, MB; Mayer, MM; Rommel, FA; Tashjian, AH | 1 |
| Cho, YS; Lamar, C; Peraino, C; Pitot, HC | 1 |
| Potter, VR; Webb, TE | 1 |
| Plagemann, PG; Swim, HE | 1 |
| Webb, TE | 1 |
| Ichii, S; Omata, S | 1 |
| Kwan, SW; Morris, HP; Webb, TE | 1 |
| Ip, PM; Sung, SC | 1 |
| Ito, J; Johnson, WW | 1 |
| Busch, H; Choi, YC | 1 |
| Miura, Y | 1 |
| Hirono, I; Kachi, H; Nishio, Y; Shibuya, C | 1 |
| Korbecki, M; Mahy, BW; Plagemann, PG; Ward, GA | 1 |
| Filler, RM; Tefft, M; Traggis, D | 1 |
| Unuma, T | 1 |
| Sakurai, Y; Tashiro, T | 1 |
| Raina, PN; Rosen, F | 1 |
| Korbecki, M; Plagemann, PG | 1 |
| Bernhard, W; Zotikov, L | 1 |
| Morris, HP; Potter, VR; Watanabe, M | 1 |
| Pitot, HC; Sladek, NE | 1 |
| Morris, HP; Wu, C | 1 |
| Cleveland, PH; Plagemann, PG; Shea, MA | 1 |
| Gaĭtskhoki, VS; Kiselev, OI; Shaposhnikov, IaD | 1 |
| Ferdinandus, JA; Morris, HP; Weber, G | 1 |
| Ballard, PL; Tomkins, GM | 1 |
| Omi, K | 1 |
| Keeling, JW | 1 |
| Inoue, H; Kaplan, JH; Pitot, HC | 1 |
| Higashi, T; Kashiwagi, K; Tobe, T | 1 |
| Busch, H; Okada, S | 1 |
| Gelehrter, TD; Risser, WL | 1 |
| Baker, WH; McArthur, JW; Quinby, WC; Reiss, AM; Russfield, AB; Toll, GD | 1 |
| Korbecki, M | 1 |
| Criss, WE; Morris, HP | 1 |
| Criss, WE | 1 |
| Blackledge, A; Hogan, B | 1 |
| Dybing, E | 2 |
| Hoogenraad, NJ; Lee, DC | 1 |
| Goldstein, L; Ko, C | 1 |
| Kirsten, ES; Watson, JA | 1 |
| Katsuta, H; Nitta, K; Nose, K; Takaoka, T | 1 |
| Kennan, AL; Lamar, C; Peraino, C; Pitot, HC | 1 |
| Curran, JF; Thompson, EB; Tomkins, GM | 1 |
| Kenney, FT; Reel, JR | 1 |
| Boctor, A; Grossman, A; Mendelson, D | 2 |
| Bresler, MA; Martin, DW; Tomkins, GM | 1 |
| Gelehrter, TD; Tomkins, GM | 2 |
| Auricchio, F; Martin, D; Tompkins, G | 1 |
| Hoel, DG; Kenney, F; Lee, KL; Reel, JR | 1 |
| Granner, DK; Thompson, EB; Tomkins, GM | 1 |
| Becker, JE; Butcher, FR; Potter, VR | 1 |
| Levitan, IB; Morris, HP; Webb, TE | 1 |
| Levinson, BB; Stellwagen, RH; Tomkins, GM | 1 |
| Chaplain, M; Weiss, MC | 1 |
| Boctor, A; Grossman, A; Masuda, Y | 1 |
| Hogan, BL | 1 |
| McKibbin, JB; Wicks, WD | 1 |
| Benedict, WF; Nebert, DW; Thompson, EB | 1 |
| Becker, JE; Bushnell, DE; Butcher, FR; Potter, VR | 1 |
| Baxter, JD; Dethlefsen, L; Levinson, BB; Tomkins, GM | 1 |
2 review(s) available for dactinomycin and Carcinoma, Hepatocellular
| Article | Year |
|---|---|
Some antineoplastic antibiotics.
Topics: Adenocarcinoma; Amino Sugars; Animals; Antibiotics, Antineoplastic; Azaserine; Benzazepines; Bleomycin; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Cricetinae; Dactinomycin; Daunorubicin; DNA; Dogs; Glycosides; Haplorhini; Humans; Leukemia L1210; Liver Neoplasms; Lymphoma; Mice; Mitomycins; Naphthacenes; Plicamycin; Pyrroles; Rats; RNA; Sarcoma 180; Streptonigrin; Streptozocin | 1972 |
Endoplasmic reticulum and phenotypic variability in normal and neoplastic liver.
Topics: Adrenal Glands; Animals; Carcinoma, Hepatocellular; Cell Differentiation; Cell Transformation, Neoplastic; Dactinomycin; Endoplasmic Reticulum; L-Serine Dehydratase; Liver; Liver Neoplasms; Models, Biological; Neoplasms, Experimental; Phenotype; Rats; RNA; RNA, Messenger; RNA, Neoplasm; Templates, Genetic | 1969 |
193 other study(ies) available for dactinomycin and Carcinoma, Hepatocellular
| Article | Year |
|---|---|
Taxane diterpenoids from the stem bark of Taxus mairei.
Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Hepatocellular; Humans; Magnetic Resonance Spectroscopy; Molecular Structure; Paclitaxel; Plant Stems; Plants, Medicinal; Structure-Activity Relationship; Taxoids; Tumor Cells, Cultured | 2001 |
Crosstalk Influence between P38MAPK and Autophagy on Mitochondria-Mediated Apoptosis Induced by Anti-Fas Antibody/Actinomycin D in Human Hepatoma Bel-7402 Cells.
Topics: Antibodies, Monoclonal; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Biomarkers; Carcinoma, Hepatocellular; Cell Line, Tumor; Dactinomycin; fas Receptor; Humans; Liver Neoplasms; Membrane Potential, Mitochondrial; Mitochondria; p38 Mitogen-Activated Protein Kinases; Signal Transduction | 2017 |
Effects of Epothilone A in Combination with the Antidiabetic Drugs Metformin and Sitagliptin in HepG2 Human Hepatocellular Cancer Cells: Role of Transcriptional Factors NF-κB and p53.
Topics: Antineoplastic Agents; Apoptosis; Benzoxazoles; Carcinoma, Hepatocellular; Dactinomycin; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Epothilones; Hep G2 Cells; Humans; Hypoglycemic Agents; Liver Neoplasms; Metformin; NF-kappa B; Sitagliptin Phosphate; Tumor Suppressor Protein p53 | 2016 |
Caveolin-1 promotes the transformation and anti-apoptotic ability of mouse hepatoma cells.
Topics: Animals; Antibiotics, Antineoplastic; Apoptosis; Carcinoma, Hepatocellular; Caveolin 1; Cell Line, Tumor; Cell Transformation, Neoplastic; Dactinomycin; Humans; In Situ Nick-End Labeling; Inhibitor of Apoptosis Proteins; Liver Neoplasms; Mice; Microtubule-Associated Proteins; Repressor Proteins; RNA Interference; Signal Transduction; Survivin | 2008 |
Sulforaphane induces CYP1A1 mRNA, protein, and catalytic activity levels via an AhR-dependent pathway in murine hepatoma Hepa 1c1c7 and human HepG2 cells.
Topics: Animals; Brassica; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Transformation, Neoplastic; Cytochrome P-450 CYP1A1; Dactinomycin; Dose-Response Relationship, Drug; Humans; Isothiocyanates; Liver Neoplasms; Mice; Plant Extracts; Receptors, Aryl Hydrocarbon; Sulfoxides; Thiocyanates; Transcription, Genetic | 2009 |
Interaction of actinomycin D with promoter element of c-met and its inhibitory effect on the expression of c-Met.
Topics: Blotting, Western; Carcinoma, Hepatocellular; Circular Dichroism; Dactinomycin; DNA Primers; Gene Expression Regulation; Humans; Immunoenzyme Techniques; Liver Neoplasms; Models, Chemical; Nucleic Acid Conformation; Promoter Regions, Genetic; Protein Synthesis Inhibitors; Proto-Oncogene Proteins c-met; Regulatory Sequences, Nucleic Acid; Thermodynamics; Tumor Cells, Cultured | 2009 |
Possible roles of a tumor suppressor gene PIG11 in hepatocarcinogenesis and As2O3-induced apoptosis in liver cancer cells.
Topics: Adult; Apoptosis; Arsenic Trioxide; Arsenicals; Carcinoma, Hepatocellular; Cell Line, Tumor; Child; Cycloheximide; Dactinomycin; Down-Regulation; Female; Gene Expression; Gene Knockdown Techniques; Genes, Tumor Suppressor; Humans; Immunohistochemistry; Liver; Liver Neoplasms; Male; Middle Aged; Neoplasm Proteins; Nucleic Acid Synthesis Inhibitors; Oxides; Protein Synthesis Inhibitors | 2009 |
RNAi-mediated silencing of insulin receptor substrate-4 enhances actinomycin D- and tumor necrosis factor-alpha-induced cell death in hepatocarcinoma cancer cell lines.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma, Hepatocellular; Dactinomycin; Humans; Immunohistochemistry; Insulin Receptor Substrate Proteins; Liver Neoplasms; RNA Interference; Tumor Necrosis Factor-alpha | 2009 |
TRAIL-mediated apoptosis requires NF-kappaB inhibition and the mitochondrial permeability transition in human hepatoma cells.
Topics: Adaptor Proteins, Signal Transducing; Antibiotics, Antineoplastic; Apoptosis; Apoptosis Regulatory Proteins; Carcinoma, Hepatocellular; Carrier Proteins; Caspase 3; Caspase 8; Caspase 9; Caspases; Cell Membrane Permeability; Dactinomycin; Fas-Associated Death Domain Protein; Humans; I-kappa B Kinase; Liver Neoplasms; Membrane Glycoproteins; Membrane Potentials; Mitochondria; NF-kappa B; NF-kappaB-Inducing Kinase; Phosphorylation; Protein Serine-Threonine Kinases; Proteins; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor; Recombinant Proteins; TNF Receptor-Associated Factor 2; TNF-Related Apoptosis-Inducing Ligand; Transcription Factor RelA; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2002 |
Cellular FLICE/caspase-8-inhibitory protein as a principal regulator of cell death and survival in human hepatocellular carcinoma.
Topics: Apoptosis; Carcinoma, Hepatocellular; Carrier Proteins; CASP8 and FADD-Like Apoptosis Regulating Protein; Cell Survival; Cycloheximide; Dactinomycin; Down-Regulation; fas Receptor; Humans; Intracellular Signaling Peptides and Proteins; Jurkat Cells; Liver; Liver Neoplasms; NF-kappa B; Oligodeoxyribonucleotides, Antisense; Protein Synthesis Inhibitors; Tumor Cells, Cultured | 2003 |
HOMOTRANSPLANTATION OF THE LIVER IN HUMANS.
Topics: Autopsy; Carcinoma, Hepatocellular; Child; Dactinomycin; Geriatrics; Humans; Liver; Liver Cirrhosis; Liver Neoplasms; Perfusion; Postoperative Complications; Prednisone; Pulmonary Embolism; Transplantation; Transplantation, Homologous | 1963 |
TRYPTOPHAN PYRROLASE ACTIVITY IN TRANSPLANTED "MINIMAL-DEVIATION" HEPATOMAS.
Topics: Anti-Bacterial Agents; Carcinoma, Hepatocellular; Cortisone; Dactinomycin; Liver; Liver Neoplasms; Neoplasms; Neoplasms, Experimental; Oxidation-Reduction; Oxygenases; Pathology; Puromycin; Rats; Renal Artery; Research; Transplantation; Tryptophan; Tryptophan Oxygenase | 1964 |
THE EFFECT OF ACTINOMYCIN D ON THE INCORPORATION OF C14-FORMATE INTO NUCLEIC ACIDS OF EHRLICH ASCITES CARCINOMA AND NOVIKOFF HEPATOMA IN VITRO.
Topics: Adenine; Animals; Ascites; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Dactinomycin; DNA; DNA, Neoplasm; Formates; Guanine; In Vitro Techniques; Liver Neoplasms; Liver Neoplasms, Experimental; Pharmacology; Research; RNA; RNA, Neoplasm; Thymine | 1964 |
INCREASED STABILITY OF TEMPLATES FOR SOME ENZYMES OF DNA SYNTHESIS IN TUMORS: DEOXYCYTIDYLATE DEAMINASE, THYMIDINE AND THYMIDYLATE KINASE.
Topics: Animals; Carcinoma, Hepatocellular; Chick Embryo; Dactinomycin; DCMP Deaminase; DNA; DNA, Neoplasm; Ligases; Liver Neoplasms; Metabolism; Neoplasms, Experimental; Nucleoside-Phosphate Kinase; Pharmacology; Phosphotransferases; Radiation Effects; Rats; Research; RNA; RNA, Messenger; Thymidine; Thymidine Kinase | 1964 |
MALIGNANT INTRA-ABDOMINAL TUMOURS.
Topics: Abdominal Neoplasms; Carcinoma, Hepatocellular; Child; Dactinomycin; Diagnosis; Dysgerminoma; Female; Granulosa Cell Tumor; Hemangioma; Hemangioma, Cavernous; Humans; Infant; Liver Neoplasms; Mesenchymoma; Neoplasms; Nephrectomy; Neuroblastoma; Ovarian Neoplasms; Pathology; Prognosis; Rhabdomyosarcoma; Surgical Procedures, Operative; Teratoma; Urography; Wilms Tumor | 1965 |
STUDIES ON THE METABOLISM OF RAT-ASCITES-HEPATOMA WITH NITROGEN MUSTARD SENSITIVE AND RESISTANT STRAINS. 8. EFFECT OF CHROMOMYCIN A3 ON THE NUCLEAR RNA METABOLISM.
Topics: Anti-Bacterial Agents; Ascites; Carcinoma, Hepatocellular; Cell Nucleus; Chromomycin A3; Dactinomycin; Liver Neoplasms; Mechlorethamine; Metabolism; Neoplasms; Neoplasms, Experimental; Pharmacology; Rats; Research; RNA; RNA, Neoplasm; RNA, Nuclear | 1965 |
Oxygen-regulated expression of the RNA-binding proteins RBM3 and CIRP by a HIF-1-independent mechanism.
Topics: Animals; Antioxidants; Aryl Hydrocarbon Receptor Nuclear Translocator; Burkitt Lymphoma; Carcinoma, Hepatocellular; Cell Hypoxia; Cell Line, Tumor; Cyanides; Dactinomycin; DNA-Binding Proteins; Gene Expression Profiling; Gene Expression Regulation; Humans; Hypothermia; Hypoxia-Inducible Factor 1, alpha Subunit; Mice; Mitochondria; Oxidation-Reduction; Oxygen; Receptors, Aryl Hydrocarbon; RNA-Binding Proteins; RNA, Messenger; Sodium Azide; Transcription Factors; Transcriptional Activation | 2004 |
Interaction of heterogeneous nuclear ribonucleoprotein A1 with cytochrome P450 2A6 mRNA: implications for post-transcriptional regulation of the CYP2A6 gene.
Topics: 3' Untranslated Regions; Animals; Aryl Hydrocarbon Hydroxylases; Base Sequence; Carcinoma, Hepatocellular; Cytochrome P-450 CYP2A6; Dactinomycin; Gene Expression Regulation, Enzymologic; Hepatocytes; Heterogeneous Nuclear Ribonucleoprotein A1; Heterogeneous-Nuclear Ribonucleoprotein Group A-B; Humans; Mice; Mixed Function Oxygenases; Molecular Sequence Data; Molecular Weight; Precipitin Tests; Protein Structure, Secondary; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured | 2004 |
Midkine protects hepatocellular carcinoma cells against TRAIL-mediated apoptosis through down-regulation of caspase-3 activity.
Topics: Apoptosis; Apoptosis Regulatory Proteins; Carcinoma, Hepatocellular; Carrier Proteins; Caspase 3; Caspases; Cytokines; Dactinomycin; Down-Regulation; Flow Cytometry; Humans; Liver Neoplasms; Membrane Glycoproteins; Midkine; Protein Synthesis Inhibitors; Tetrazolium Salts; TNF-Related Apoptosis-Inducing Ligand; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2004 |
Key role of the achievement of an appropriate ribosomal RNA complement for G1-S phase transition in H4-II-E-C3 rat hepatoma cells.
Topics: Animals; Carcinoma, Hepatocellular; Cell Division; Cell Line, Tumor; Cyclin E; Dactinomycin; G1 Phase; Insulin; Liver Neoplasms; Nucleic Acid Synthesis Inhibitors; Rats; RNA, Messenger; RNA, Ribosomal; S Phase; Time Factors | 2005 |
Functional expression and adaptive regulation of Na+ -dependent neutral amino acid transporter SNAT2/ATA2 in normal human astrocytes under amino acid starved condition.
Topics: Amino Acid Transport System A; Amino Acids; Astrocytes; beta-Alanine; Blotting, Northern; Carbon Isotopes; Carcinoma, Hepatocellular; Cells, Cultured; Culture Media, Conditioned; Cycloheximide; Dactinomycin; Drug Interactions; Gene Expression Regulation; Humans; Hydrogen-Ion Concentration; Protein Synthesis Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium; Time Factors | 2005 |
P-glycoprotein expression induced by glucose depletion enhanced the chemosensitivity in human hepatocellular carcinoma cell-lines.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Hepatocellular; Cell Line, Tumor; Culture Media; Dactinomycin; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Fluorouracil; Glucose; Humans; Inhibitory Concentration 50; Paclitaxel; Vinblastine; Vincristine | 2005 |
Regulatory mechanisms modulating the expression of cytochrome P450 1A1 gene by heavy metals.
Topics: Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cycloheximide; Cytochrome P-450 CYP1A1; Dactinomycin; Drug Interactions; Enzyme Induction; Gene Expression Regulation, Neoplastic; Hepatocytes; Leupeptins; Metals, Heavy; Mice; Polychlorinated Dibenzodioxins; Protein Processing, Post-Translational; Protein Synthesis Inhibitors; Receptors, Aryl Hydrocarbon; Receptors, Cytoplasmic and Nuclear; Response Elements; RNA, Messenger | 2005 |
Involvement of p38 MAPK and Nrf2 in phenolic acid-induced P-form phenol sulfotransferase expression in human hepatoma HepG2 cells.
Topics: Arylsulfotransferase; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Cycloheximide; Dactinomycin; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Hydroxybenzoates; NF-E2-Related Factor 2; p38 Mitogen-Activated Protein Kinases; Reverse Transcriptase Polymerase Chain Reaction | 2006 |
Sulindac regulates the aryl hydrocarbon receptor-mediated expression of Phase 1 metabolic enzymes in vivo and in vitro.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Hepatocellular; Cytochrome P-450 CYP1A1; Dactinomycin; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Humans; In Vitro Techniques; Liver; Liver Neoplasms; Male; Promoter Regions, Genetic; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, Aryl Hydrocarbon; RNA, Messenger; Sulindac; Transcription, Genetic; Tumor Cells, Cultured; Xenobiotics | 2006 |
Heat shock protein 70 binds its own messenger ribonucleic acid as part of a gene expression self-limiting mechanism.
Topics: Blotting, Northern; Carcinoma, Hepatocellular; Cell Line, Tumor; Cycloheximide; Dactinomycin; Electrophoretic Mobility Shift Assay; Gene Expression Regulation; Heat-Shock Response; HeLa Cells; HSP70 Heat-Shock Proteins; Humans; Liver Neoplasms; Precipitin Tests; Protein Synthesis Inhibitors; Puromycin; RNA, Messenger; Transcription, Genetic | 2006 |
Hepatitis C virus core protein inhibits deoxycholic acid-mediated apoptosis despite generating mitochondrial reactive oxygen species.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Antioxidants; Apoptosis; Apoptosis Regulatory Proteins; bcl-2-Associated X Protein; bcl-X Protein; Carcinoma, Hepatocellular; Cell Line, Tumor; Cytochromes c; Cytosol; Dactinomycin; Deoxycholic Acid; Deoxyguanosine; Enzyme Activation; Humans; Intracellular Membranes; Liver Neoplasms; Mitochondria, Liver; Oxidative Stress; Protein Synthesis Inhibitors; Reactive Oxygen Species; Superoxide Dismutase; Tumor Necrosis Factor-alpha; Viral Core Proteins | 2006 |
Dehydroepiandrosterone effects on the mRNA levels of peroxisome proliferator-activated receptors and their coactivators in human hepatoma HepG2 cells.
Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Cycloheximide; Dactinomycin; Dehydroepiandrosterone; Gene Expression Regulation, Neoplastic; Humans; Peroxisome Proliferator-Activated Receptors; Protein Isoforms; RNA, Messenger | 2007 |
Regulation of tyrosine aminotransferase mRNA in HTC cells.
Topics: Animals; Carcinoma, Hepatocellular; Cell Line; Cycloheximide; Dactinomycin; Dexamethasone; Emetine; Enzyme Induction; Kinetics; Liver Neoplasms; Protein Biosynthesis; Rats; RNA, Messenger; Tyrosine Transaminase | 1980 |
Tumor cell lipid composition and sensitivity to humoral immune killing. I. Modification of cellular lipid and fatty acid content by metabolic inhibitors and hormones.
Topics: Animals; Carcinoma, Hepatocellular; Cardiolipins; Cattle; Cholesterol; Cytotoxicity, Immunologic; Dactinomycin; Doxorubicin; Fatty Acids; Fluorouracil; Guinea Pigs; Insulin; Lipids; Liver Neoplasms; Lysophosphatidylcholines; Phosphatidylcholines | 1980 |
Epidermal growth factor stimulation of ornithine decarboxylase activity in a human hepatoma cell line.
Topics: Ammonium Chloride; Carboxy-Lyases; Carcinoma, Hepatocellular; Cell Line; Chloroquine; Colchicine; Cycloheximide; Dactinomycin; Enzyme Induction; Epidermal Growth Factor; ErbB Receptors; Humans; Kinetics; Liver Neoplasms; Ornithine Decarboxylase; Peptides; Receptors, Cell Surface | 1981 |
Preoperative chemotherapy for unresectable primary hepatic malignancies in children.
Topics: Adolescent; Antineoplastic Agents; Carcinoma, Hepatocellular; Child; Child, Preschool; Cyclophosphamide; Dacarbazine; Dactinomycin; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Follow-Up Studies; Humans; Infant; Liver Neoplasms; Male; Vincristine | 1982 |
An episomal expression vector system for monitoring sequence-specific effects on mRNA stability in human cell lines.
Topics: Base Sequence; Blotting, Northern; Carcinoma, Hepatocellular; Cell Line; Cloning, Molecular; Dactinomycin; DNA, Complementary; Gene Expression; Genetic Vectors; Globins; Humans; Hydroxymethylglutaryl CoA Reductases; Liver Neoplasms; Molecular Sequence Data; Plasmids; Recombinant Fusion Proteins; Recombinant Proteins; Repetitive Sequences, Nucleic Acid; Restriction Mapping; RNA; RNA, Messenger; Transfection; Tumor Cells, Cultured | 1995 |
Transforming growth factor beta 1 selectively increases gene expression of the serine/threonine kinase receptor 1 (SKR1) in human hepatoma cell lines.
Topics: Blotting, Northern; Carcinoma, Hepatocellular; Cell Division; Cycloheximide; Dactinomycin; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-myc; Receptors, Growth Factor; Receptors, Transforming Growth Factor beta; RNA, Messenger; Transforming Growth Factor beta; Tumor Cells, Cultured | 1994 |
The role of inorganic metals and metalloporphyrins in the induction of haem oxygenase and heat-shock protein 70 in human hepatoma cells.
Topics: Carcinoma, Hepatocellular; Dactinomycin; Ferrochelatase; Heat-Shock Proteins; Heme Oxygenase (Decyclizing); Hemin; Humans; Liver Neoplasms; Metalloporphyrins; Metals; Protoporphyrins; RNA, Messenger; Tin; Tin Compounds; Transcription, Genetic; Tumor Cells, Cultured | 1993 |
Biosynthesis of human acute-phase serum amyloid A protein (A-SAA) in vitro: the roles of mRNA accumulation, poly(A) tail shortening and translational efficiency.
Topics: Base Sequence; Blotting, Northern; Carcinoma, Hepatocellular; Culture Media, Conditioned; Dactinomycin; Drug Stability; Electrophoresis, Polyacrylamide Gel; Humans; Interleukin-1; Interleukin-6; Kinetics; Liver Neoplasms; Molecular Sequence Data; Monocytes; Poly A; Protein Biosynthesis; RNA, Messenger; Serum Amyloid A Protein; Tumor Cells, Cultured | 1993 |
Tumor necrosis factor up-regulates expression of low-density lipoprotein receptors on HepG2 cells.
Topics: Carcinoma, Hepatocellular; Cycloheximide; Dactinomycin; Humans; Lipoproteins, LDL; Liver Neoplasms; Receptors, LDL; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Up-Regulation | 1993 |
TCDD-inducible plasminogen activator inhibitor type 2 (PAI-2) in human hepatocytes, HepG2 and monocytic U937 cells.
Topics: Aryl Hydrocarbon Receptor Nuclear Translocator; Carcinoma, Hepatocellular; Cytochrome P-450 Enzyme System; Dactinomycin; DNA-Binding Proteins; Humans; Liver; Liver Neoplasms; Plasminogen Activator Inhibitor 2; Polychlorinated Dibenzodioxins; Protein Synthesis Inhibitors; Receptors, Aryl Hydrocarbon; RNA, Messenger; Serine Proteinase Inhibitors; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription Factors; Tumor Cells, Cultured | 1996 |
Transcriptional induction of rat liver apolipoprotein A-I gene expression by glucocorticoids requires the glucocorticoid receptor and a labile cell-specific protein.
Topics: Animals; Apolipoprotein A-I; Apolipoprotein A-II; Base Sequence; Carcinoma, Hepatocellular; Cell Line; Cell Nucleus; Cells, Cultured; Chloramphenicol O-Acetyltransferase; Chlorocebus aethiops; Cloning, Molecular; Dactinomycin; Dexamethasone; DNA Primers; Glucocorticoids; Kinetics; Liver; Male; Mifepristone; Molecular Sequence Data; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Recombinant Proteins; RNA, Messenger; Transcription, Genetic; Transfection | 1996 |
Chemotherapeutic agent CPT-11 induces the new expression of the apoptosis initiator to the cytoplasm.
Topics: Amino Acid Sequence; Animals; Apoptosis; Camptothecin; Carcinoma, Hepatocellular; Caspase 1; Cell Extracts; Cell Nucleus; Cycloheximide; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Cytoplasm; Dactinomycin; DNA; Humans; Irinotecan; Liver; Liver Neoplasms; Male; Molecular Sequence Data; Oligopeptides; Protein Synthesis Inhibitors; Rats; Tumor Cells, Cultured | 1996 |
Glucocorticoid regulation of hepatic S-adenosylmethionine synthetase gene expression.
Topics: Adrenalectomy; Animals; Carcinoma, Hepatocellular; Cells, Cultured; Cycloheximide; Dactinomycin; Gene Expression Regulation; Glucocorticoids; Insulin Antagonists; Liver; Male; Methionine Adenosyltransferase; Protein Synthesis Inhibitors; Rats; Rats, Wistar; RNA, Messenger; Transcription, Genetic; Triamcinolone | 1997 |
Enhanced expression of glucose-6-phosphate dehydrogenase in human cells sustaining oxidative stress.
Topics: Carcinoma, Hepatocellular; Catalase; Cycloheximide; Dactinomycin; Diamide; Enzyme Induction; Glucosephosphate Dehydrogenase; Glutathione; Humans; Hydrogen Peroxide; Leukemia-Lymphoma, Adult T-Cell; Liver Neoplasms; Neoplasm Proteins; Nucleic Acid Synthesis Inhibitors; Oxidation-Reduction; Oxidative Stress; Protein Synthesis Inhibitors; RNA, Messenger; RNA, Neoplasm; Tumor Cells, Cultured | 1997 |
Induction of apoptosis in human hepatoma cells by alpha-fetoprotein.
Topics: alpha-Fetoproteins; Apoptosis; Carcinoma, Hepatocellular; Cell Division; Dactinomycin; DNA Fragmentation; Dose-Response Relationship, Drug; Humans; Liver Neoplasms; Tumor Cells, Cultured | 1997 |
Glucose response elements in a gene that codes for 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase.
Topics: Animals; Carcinoma, Hepatocellular; Dactinomycin; Enhancer Elements, Genetic; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Genes; Glucose; Insulin; Lactic Acid; Nucleic Acid Synthesis Inhibitors; Okadaic Acid; Phosphofructokinase-2; Phosphoprotein Phosphatases; Phosphoric Monoester Hydrolases; Phosphotransferases (Alcohol Group Acceptor); Promoter Regions, Genetic; Pyruvic Acid; Rats; Regulatory Sequences, Nucleic Acid; RNA, Messenger; Tumor Cells, Cultured; Xylitol | 1997 |
Upregulation of low density lipoprotein receptor by gemfibrozil, a hypolipidemic agent, in human hepatoma cells through stabilization of mRNA transcripts.
Topics: Carcinoma, Hepatocellular; Dactinomycin; ErbB Receptors; Gemfibrozil; Gene Expression Regulation, Neoplastic; Genes, Reporter; Half-Life; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Liver Neoplasms; Mevalonic Acid; Neoplasm Proteins; Pravastatin; Promoter Regions, Genetic; Receptors, LDL; RNA, Messenger; RNA, Neoplasm; Transfection; Tumor Cells, Cultured; Up-Regulation | 1997 |
LBR, a chromatin and lamin binding protein from the inner nuclear membrane, is proteolyzed at late stages of apoptosis.
Topics: Animals; Aphidicolin; Apoptosis; Carcinoma, Hepatocellular; Cell Fractionation; Chickens; Chromatin; Dactinomycin; Enzyme Inhibitors; Lamin B Receptor; Lamin Type B; Lamins; Nuclear Envelope; Nuclear Proteins; Phosphorylation; Protein Synthesis Inhibitors; Receptors, Cytoplasmic and Nuclear; Tumor Cells, Cultured | 1998 |
Post-transcriptional control of the level of mRNA by hepatitis B virus X gene in the transient expression system using human hepatic cells.
Topics: Antigens, Polyomavirus Transforming; Carcinoma, Hepatocellular; Chloramphenicol O-Acetyltransferase; Dactinomycin; Gene Expression Regulation, Viral; Genes, Viral; Hepatitis B virus; Hepatoblastoma; Humans; Liver; Nucleic Acid Synthesis Inhibitors; Peptide Elongation Factor 1; Peptide Elongation Factors; Promoter Regions, Genetic; RNA, Messenger; RNA, Viral; Sequence Deletion; Simian virus 40; Trans-Activators; Transcription, Genetic; Transfection; Tumor Cells, Cultured; Viral Regulatory and Accessory Proteins | 1998 |
Transcriptional and post-transcriptional regulation of complement factor I (CFI) gene expression in Hep G2 cells by interleukin-6.
Topics: Base Sequence; Carcinoma, Hepatocellular; Chloramphenicol O-Acetyltransferase; Complement Factor I; Consensus Sequence; Cycloheximide; Dactinomycin; Gene Expression Regulation, Neoplastic; Genes, Reporter; Half-Life; Humans; Interleukin-1; Interleukin-6; Kinetics; Liver Neoplasms; Promoter Regions, Genetic; Recombinant Fusion Proteins; Regulatory Sequences, Nucleic Acid; RNA Processing, Post-Transcriptional; RNA, Messenger; Transcription, Genetic; Transfection | 1998 |
Transcriptional modulation of the human complement factor I gene in Hep G2 cells by protein kinase C activation.
Topics: Carcinoma, Hepatocellular; Complement Factor I; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cycloheximide; Dactinomycin; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation; Humans; Mutagenesis, Site-Directed; Naphthalenes; Nucleic Acid Synthesis Inhibitors; Protein Kinase C; Protein Synthesis Inhibitors; Pyrrolidines; Recombinant Proteins; RNA Stability; RNA, Messenger; Tetradecanoylphorbol Acetate; Thiocarbamates; Transcription, Genetic; Tumor Cells, Cultured; Up-Regulation | 1999 |
Chemotherapeutic agents augment TRAIL-induced apoptosis in human hepatocellular carcinoma cell lines.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Camptothecin; Carcinoma, Hepatocellular; Dactinomycin; Doxorubicin; Humans; Liver Neoplasms; Membrane Glycoproteins; NF-kappa B; Receptors, Tumor Necrosis Factor; TNF-Related Apoptosis-Inducing Ligand; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2000 |
Study of multi-drug resistant mechanisms in a taxol-resistant hepatocellular carcinoma QGY-TR 50 cell line.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Hepatocellular; Cell Survival; Dactinomycin; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Inhibitory Concentration 50; Mitomycin; Paclitaxel; Protein Isoforms; Reverse Transcriptase Polymerase Chain Reaction; RNA, Neoplasm; Time Factors; Tubulin; Tumor Cells, Cultured; Vinblastine; Vincristine | 2001 |
Cold-stimulated increase in a regulatory subunit of cAMP-dependent protein kinase in human hepatoblastoma cells.
Topics: Carcinoma, Hepatocellular; Cold Temperature; Cyclic AMP-Dependent Protein Kinases; Dactinomycin; Enzyme Stability; Gene Expression; Humans; Liver Neoplasms; Nucleic Acid Synthesis Inhibitors; Oligonucleotide Array Sequence Analysis; Protein Subunits; RNA, Messenger; Signal Transduction; Tumor Cells, Cultured | 2001 |
Induction of UDP-glucuronosyltransferase 1A8 mRNA by 3-methylcholanthene in rat hepatoma cells.
Topics: Amino Acid Sequence; Animals; Base Sequence; Carcinoma, Hepatocellular; Dactinomycin; Glucuronosyltransferase; Methylcholanthrene; Molecular Sequence Data; Nucleic Acid Synthesis Inhibitors; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA Stability; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured | 2002 |
Differential degradation of messenger RNAs in mammalian cells.
Topics: Alanine Transaminase; Carcinoma, Hepatocellular; Cell Line; Cycloheximide; Dactinomycin; Enzyme Induction; Fluorides; Hydrocortisone; Liver Neoplasms; Peptide Chain Elongation, Translational; Polyribosomes; Puromycin; RNA, Messenger; Tyrosine Transaminase | 1976 |
Spermine inhibits induction of ornithine decarboxylase by cyclic AMP but not by dexamethasone in rat hepatoma cells.
Topics: Animals; Bucladesine; Carboxy-Lyases; Carcinoma, Hepatocellular; Cell Line; Cyclic AMP; Cycloheximide; Dactinomycin; Dexamethasone; Enzyme Induction; Liver Neoplasms; Ornithine Decarboxylase; Rats; Spermine | 1975 |
Lysis of tumor cells by antibody and complement. III. Lack of correlation between antigen movement and cell lysis.
Topics: Animals; Antibodies; Antibodies, Neoplasm; Antigens; Azides; Carcinoma, Hepatocellular; Cell Membrane; Colchicine; Complement System Proteins; Cyanides; Cycloheximide; Cytochalasin B; Cytotoxicity Tests, Immunologic; Dactinomycin; Fluorescent Antibody Technique; Fluorides; Forssman Antigen; Guinea Pigs; Immunity, Cellular; Iodoacetates; Liver Neoplasms; Puromycin; Staining and Labeling | 1975 |
Enhancing effect by metabolic inhibitors on the killing of tumor cells by antibody and complement.
Topics: Animals; Antibodies, Neoplasm; Antigen-Antibody Reactions; Antineoplastic Agents; Azacitidine; Carcinoma, Hepatocellular; Cells, Cultured; Complement System Proteins; Cyclophosphamide; Cytarabine; Dactinomycin; Doxorubicin; Fluorouracil; Guinea Pigs; Hydroxyurea; Liver Neoplasms; Mercaptopurine; Methotrexate; Mitomycins; Neoplasms, Experimental; Puromycin; Vincristine | 1975 |
Effect of metabolic inhibitors on the ability of tumor cells to express antigen and bind complement components C4 and C3.
Topics: Animals; Antigen-Antibody Reactions; Antigens, Neoplasm; Antineoplastic Agents; Azacitidine; Binding Sites, Antibody; Carcinoma, Hepatocellular; Cell Membrane; Cells, Cultured; Complement C3; Complement C4; Complement System Proteins; Dactinomycin; Doxorubicin; Guinea Pigs; Liver Neoplasms; Methotrexate; Neoplasms, Experimental; Puromycin | 1975 |
Influence of serum and insulin on the accumulation of aminoisobutyrate by rat hepatoma cells.
Topics: Alanine; Aminoisobutyric Acids; Animals; Blood; Carcinoma, Hepatocellular; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Insulin; Kinetics; Liver Neoplasms; Rats | 1976 |
Effects of adriamycin and actinomycin D on nucleolar morphology: A simple biologic assay.
Topics: Animals; Carcinoma, Hepatocellular; Cell Nucleolus; Dactinomycin; Doxorubicin; Liver Neoplasms; Male; Neoplasms, Experimental; Rats; Ribonucleoproteins; Staining and Labeling; Tolonium Chloride | 1977 |
[Biological properties of the modified actinomycins synthesized by the aurantin producer].
Topics: Amino Acids; Animals; Carcinoma, Hepatocellular; Dactinomycin; DNA, Bacterial; Escherichia coli; Flavonoids; Liver Neoplasms; Male; Mice; Mice, Inbred C3H; Microbial Sensitivity Tests; Mitosis; Neoplasms, Experimental; RNA, Neoplasm; Streptomyces | 1978 |
Functional differences in protein synthesis between rat liver tRNA and tRNA from Novikoff hepatoma.
Topics: Animals; Carcinoma, Hepatocellular; Chickens; Dactinomycin; Estradiol; Female; Liver; Liver Neoplasms; Male; Neoplasms, Experimental; Ovalbumin; Oviducts; Rats; Ribonucleases; RNA, Transfer | 1975 |
Nuclear DNA of mouse hepatoma studied by 3-H-actinomycin D binding.
Topics: Animals; Binding Sites; Carcinoma, Hepatocellular; Cell Nucleus; Dactinomycin; DNA, Neoplasm; Heterochromatin; Liver; Liver Neoplasms; Mice; Neoplasms, Experimental; Tritium | 1975 |
Cytoplasmic DNA of hepatoma tumor cells studied by 3H-actinomycin D binding.
Topics: Animals; Autoradiography; Binding Sites; Carcinoma, Hepatocellular; Cytoplasm; Dactinomycin; DNA, Mitochondrial; DNA, Neoplasm; Liver; Liver Neoplasms; Mice; Neoplasms, Experimental; Tritium | 1975 |
Effects of cyclic adenosine monophosphate, dexamethasone and insulin on phosphoenolpyruvate carboxykinase synthesis in Reuber H-35 hepatoma cells.
Topics: Animals; Bucladesine; Carcinoma, Hepatocellular; Cells, Cultured; Dactinomycin; Deoxyadenosines; Dexamethasone; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Glucagon; Glucose; Insulin; Kinetics; Leucine; Liver Neoplasms; Neoplasms, Experimental; Phosphoenolpyruvate Carboxykinase (GTP); Rats; RNA; RNA, Messenger; Theophylline | 1975 |
Requirement for protein synthesis in the regulation of protein breakdown in cultured hepatoma cells.
Topics: Carcinoma, Hepatocellular; Cell Line; Cycloheximide; Dactinomycin; Insulin; Liver Neoplasms; Neoplasm Proteins; Neoplasms, Experimental; Pactamycin; Protein Biosynthesis; Puromycin; RNA, Transfer | 1975 |
Regression of established tumors and induction of tumor immunity by intratumor chemotherapy.
Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Carmustine; Dacarbazine; Dactinomycin; Doxorubicin; Drug Therapy, Combination; Fluorouracil; Graft Rejection; Guinea Pigs; Injections; Injections, Intraperitoneal; Liver Neoplasms; Melphalan; Mercaptopurine; Methotrexate; Mitomycins; Neoplasm Transplantation; Neoplasms, Experimental | 1976 |
The appearance of an ornithine decarboxylase inhibitory protein upon the addition of putrescine to cell cultures.
Topics: Carboxy-Lyases; Carcinoma, Hepatocellular; Cell Line; Culture Media; Cycloheximide; Dactinomycin; Kinetics; Liver Neoplasms; Neoplasm Proteins; Neoplasms, Experimental; Ornithine Decarboxylase Inhibitors; Protein Biosynthesis; Putrescine | 1976 |
Stimulation of ornithine decarboxylase synthesis and its control by polyamines in regenerating rat liver and cultured rat hepatoma cells.
Topics: Animals; Bucladesine; Carboxy-Lyases; Carcinoma, Hepatocellular; Cell Line; Cycloheximide; Dactinomycin; Drug Stability; Enzyme Induction; Hot Temperature; Kinetics; Liver; Liver Neoplasms; Liver Regeneration; Neoplasms, Experimental; Ornithine Decarboxylase; Polyamines; Precipitin Tests; Rats; Spermidine; Spermine; Time Factors | 1976 |
The regulation of ornithine aminotransferase synthesis by glucagon in the rat.
Topics: Animals; Carcinoma, Hepatocellular; Dactinomycin; Dose-Response Relationship, Drug; Enzyme Induction; Glucagon; Immunodiffusion; Kidney; Liver Neoplasms; Male; Mitochondria; Mitochondria, Liver; Molecular Weight; Neoplasms, Experimental; Organ Specificity; Ornithine-Oxo-Acid Transaminase; Precipitin Tests; Rats; Transaminases | 1976 |
The induction of tumour cell adhesiveness and intercellular junctions by a glycoprotein of rat ascites hepatoma cell surface.
Topics: Animals; Carcinoma, Hepatocellular; Cell Adhesion; Colony-Stimulating Factors; Dactinomycin; Desmosomes; Glycoproteins; In Vitro Techniques; Intercellular Junctions; Liver Neoplasms; Microscopy, Electron; Neoplasm Proteins; Neoplasms, Experimental; Rats; Skin Neoplasms; Time Factors | 1976 |
Thymidylate synthetase activity in the Novikoff hepatoma.
Topics: Animals; Carcinoma, Hepatocellular; Cycloheximide; Dactinomycin; Folic Acid; Liver Neoplasms; Male; Methotrexate; Methyltransferases; Neoplasms, Experimental; Puromycin; Rats; Tetrahydrofolates; Thymidylate Synthase | 1976 |
Nucleic acids from subcellular fractions of N-nitrosodiethylamine-induced hepatoma in mice.
Topics: Acridines; Animals; Carcinoma, Hepatocellular; Cell Nucleus; Dactinomycin; Diethylnitrosamine; DNA, Neoplasm; Genes; Liver Neoplasms; Male; Mice; Mice, Inbred C3H; Mitochondria, Liver; Mitosis; Neoplasms, Experimental; RNA, Messenger; RNA, Neoplasm | 1976 |
Translational regulatory mechanisms in neoplasia in vivo.
Topics: Animals; Carcinoma, Hepatocellular; Dactinomycin; Enzyme Induction; Genes; Glucose; Liver Neoplasms; Neoplasms, Experimental; Protein Biosynthesis; Rats; RNA, Messenger; Tryptophan Oxygenase | 1976 |
Effect of inhibiting DNA, RNA, and protein synthesis of tumor cells on their susceptibility to killing by antibody and complement.
Topics: Antibodies; Carcinoma, Hepatocellular; Cell Line; Complement System Proteins; Cytotoxicity Tests, Immunologic; Dactinomycin; DNA, Neoplasm; Doxorubicin; Hot Temperature; Liver Neoplasms; Neoplasm Proteins; Neoplasms, Experimental; Puromycin; Radiation Effects; RNA, Neoplasm; Time Factors | 1977 |
Regulation of ornithine decarboxylase by ODC-antizyme in HTC cells.
Topics: Cadaverine; Carboxy-Lyases; Carcinoma, Hepatocellular; Cell Line; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Kinetics; Liver Neoplasms; Ornithine; Ornithine Decarboxylase; Polyamines; Putrescine; Spermidine; Spermine | 1977 |
Cytostatic efficacy of DNA-complexes of adriamycin, daunomycin and actinomycin D. I. Comparative studies in Novikoff hepatoma, human mammary carcinoma cells and human leukemic leukocytes.
Topics: Acute Disease; Animals; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Hepatocellular; Dactinomycin; Daunorubicin; DNA, Neoplasm; Doxorubicin; Female; Humans; Leukemia; Liver Neoplasms; Pinocytosis; Rats; RNA, Neoplasm | 1977 |
Effect of alpha-methyl ornithine on ornithine decarboxylase activity of rat hepatoma cells in culture.
Topics: Animals; Carboxy-Lyases; Carcinoma, Hepatocellular; Cell Division; Cells, Cultured; Cycloheximide; Dactinomycin; Liver Neoplasms; Neoplasms, Experimental; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Rats; RNA, Messenger | 1977 |
[Characteristics of mRNA metabolism in tumor cells. The hypothesis of the uncoupling of the processes of polyribosome formation and functioning in the tumor cell].
Topics: Animals; Biological Transport; Carcinoma, Hepatocellular; Cell Membrane; Cell Nucleus; Cycloheximide; Cytoplasm; Dactinomycin; Free Radicals; Liver Neoplasms; Neoplasms, Experimental; Phenylalanine; Polyribosomes; Rats; RNA, Messenger; RNA, Neoplasm; Uridine | 1977 |
Marked stimulation of lymphocyte-mediated attack on tumor cells by target-directed liposomes containing immune RNA.
Topics: Animals; Antilymphocyte Serum; Carcinoma, Hepatocellular; Cytotoxicity, Immunologic; Dactinomycin; Guinea Pigs; In Vitro Techniques; Liposomes; Liver Neoplasms; Lymphocytes; Neoplasms, Experimental; RNA | 1978 |
Turnover of messenger RNA in transplantable hepatomas and host liver of rats.
Topics: Animals; Carcinoma, Hepatocellular; Dactinomycin; Female; Liver; Liver Neoplasms; Neoplasm Transplantation; Neoplasms, Experimental; Orotic Acid; Poly A; Polyribosomes; Rats; Rats, Inbred BUF; Ribonucleases; RNA, Messenger; RNA, Neoplasm; Transplantation, Isogeneic | 1978 |
Production of unintegrated mouse mammary tumor virus DNA in infected rat hepatoma cells is a secondary action of dexamethasone.
Topics: Animals; Carcinoma, Hepatocellular; Cell Line; Cytarabine; Dactinomycin; Dexamethasone; DNA Replication; DNA, Viral; Liver Neoplasms; Mammary Tumor Virus, Mouse; Progesterone; Rats; RNA, Viral | 1978 |
Tumor cell killing by macrophages activated in vitro with lymphocyte mediators. II. Inhibition by inhibitors of protein synthesis.
Topics: Animals; Antimetabolites; Carcinoma, Hepatocellular; Cytotoxicity, Immunologic; Dactinomycin; Depression, Chemical; Guinea Pigs; Liver Neoplasms; Macrophages; Mitomycins; Neoplasms, Experimental; Pactamycin; Puromycin; Puromycin Aminonucleoside | 1978 |
Enhancement of radiation killing of cultured mammalian cells by cordycepin.
Topics: Animals; Carcinoma, Hepatocellular; Cell Survival; Cells, Cultured; Dactinomycin; Deoxyadenosines; DNA Repair; DNA, Neoplasm; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Liver Neoplasms; Radiation-Sensitizing Agents; Rats; Time Factors; X-Rays | 1978 |
"Superinduction" of tyrosine aminotransferase by actinomycin D: a reevaluation.
Topics: Animals; Carcinoma, Hepatocellular; Cell Division; Cell Line; Cell-Free System; Dactinomycin; Deoxyadenosines; Dexamethasone; DNA, Neoplasm; Enzyme Induction; Fluorometry; Liver Neoplasms; Neoplasm Proteins; Rats; RNA, Messenger; Serum Albumin, Bovine; Tyrosine Transaminase | 1975 |
Transcriptional regulation of transferrin and albumin genes by retinoic acid in human hepatoma cell line Hep3B.
Topics: Blotting, Northern; Carcinoma, Hepatocellular; Cell Division; Cell Line; Cell Nucleus; Cycloheximide; Dactinomycin; Gene Expression Regulation, Neoplastic; Humans; Kinetics; Liver Neoplasms; RNA, Neoplasm; Serum Albumin; Transcription, Genetic; Transferrin; Tretinoin | 1992 |
Differential induction of heme oxygenase in the hepatocarcinoma cell line (Hep3B) by environmental agents.
Topics: Blotting, Northern; Carcinoma, Hepatocellular; Dactinomycin; Enzyme Induction; Gene Expression Regulation; Heme Oxygenase (Decyclizing); Hemin; Humans; Kinetics; Nucleic Acid Hybridization; Porphyrins; RNA, Messenger; Tumor Cells, Cultured | 1992 |
Regulation of insulin receptor gene expression. Cell cycle-mediated effects on insulin receptor mRNA stability.
Topics: Actins; Breast Neoplasms; Carcinoma, Hepatocellular; Cell Cycle; Cell Division; Cycloheximide; Dactinomycin; DNA Probes; Exons; Female; Gene Expression Regulation, Neoplastic; Histones; Humans; Kinetics; Liver Neoplasms; Receptor, Insulin; Restriction Mapping; RNA, Messenger; Tumor Cells, Cultured | 1992 |
Heme oxygenase is a positive acute-phase reactant in human Hep3B hepatoma cells.
Topics: Acute-Phase Proteins; Carcinoma, Hepatocellular; Cycloheximide; Dactinomycin; DNA; Enzyme Induction; Heat-Shock Proteins; Heme Oxygenase (Decyclizing); Humans; Interleukin-6; Liver Neoplasms; Nuclear Proteins; Oligonucleotides; Promoter Regions, Genetic; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured | 1992 |
Interleukin-6 enhances the expression of tumor necrosis factor receptors on hepatoma cells and hepatocytes.
Topics: Animals; Carcinoma, Hepatocellular; Cell Line; Cells, Cultured; Cycloheximide; Dactinomycin; Humans; Interleukin-6; Kinetics; Liver; Liver Neoplasms; Rats; Receptors, Cell Surface; Receptors, Tumor Necrosis Factor; Tumor Necrosis Factor-alpha | 1991 |
[Immunochemo-embolization therapy of hepatocellular carcinoma].
Topics: Aged; alpha-Fetoproteins; Carcinoma, Hepatocellular; Dactinomycin; Doxorubicin; Female; Humans; Interferon-gamma; Iodized Oil; Liver Neoplasms; Male; Middle Aged; Picibanil; Tomography, X-Ray Computed | 1991 |
Cytocidal activity of a synthetic isoprenoid, N-solanesyl-N,N'-bis(3,4-dimethoxybenzyl)ethylenediamine, and its potentiation of antitumor drugs against multidrug-resistant and sensitive cells in vitro.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Cricetinae; Cytarabine; Dactinomycin; Doxorubicin; Drug Resistance; Drug Synergism; Ethylenediamines; Fluorouracil; Humans; Liver Neoplasms; Terpenes; Tumor Cells, Cultured; Vincristine | 1990 |
Butyrate induces an ectoMg2(+)-ATPase activity in Li-7A human hepatoma cells.
Topics: 4-Chloromercuribenzenesulfonate; Adenosine Triphosphatases; Biological Transport, Active; Bucladesine; Butyrates; Carcinoma, Hepatocellular; Cell Division; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Enzyme Induction; Epidermal Growth Factor; Fatty Acids; Humans; Kinetics; Liver Neoplasms; Neoplasm Proteins; Time Factors; Tumor Cells, Cultured | 1990 |
[Chemoembolization combined with hepatic arterial induction of endogenous TNF and anticancer agents for hepatocellular carcinoma--a case report].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biological Products; Carcinoma, Hepatocellular; Dactinomycin; Delayed-Action Preparations; Doxorubicin; Drug Administration Schedule; Embolization, Therapeutic; Gelatin Sponge, Absorbable; Hepatic Artery; Humans; Infusions, Intra-Arterial; Interferon-gamma; Iodized Oil; Liver Neoplasms; Male; Picibanil; Tumor Necrosis Factor-alpha | 1990 |
Regulation of the expression of the rat alcohol dehydrogenase gene by glucocorticoids.
Topics: Alcohol Dehydrogenase; Animals; Carcinoma, Hepatocellular; Cell Line; Cycloheximide; Dactinomycin; Dexamethasone; Enzyme Induction; Ethanol; Gene Expression Regulation; Genes; Humans; Liver Neoplasms; Liver Neoplasms, Experimental; Puromycin; Rats; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured | 1989 |
Metal-specific posttranscriptional control of human metallothionein genes.
Topics: Actins; Carcinoma, Hepatocellular; Cell Line; Copper; Cycloheximide; Dactinomycin; Gene Expression Regulation; Genes; Humans; Kinetics; Liver Neoplasms; Metallothionein; RNA Processing, Post-Transcriptional; RNA, Messenger; Transcription, Genetic; Zinc | 1989 |
Heat shock induction of heme oxygenase mRNA in human Hep 3B hepatoma cells.
Topics: Carcinoma, Hepatocellular; Cell Line; Cycloheximide; Dactinomycin; Enzyme Induction; Heme Oxygenase (Decyclizing); Hot Temperature; Humans; Kinetics; Liver Neoplasms; Mixed Function Oxygenases; RNA, Messenger; Tumor Cells, Cultured | 1989 |
Induced secretion of a Mr 46,000 protein by cultured human hepatoma cells treated with tumor promoters.
Topics: Carcinogens; Carcinoma, Hepatocellular; Cells, Cultured; Dactinomycin; Humans; Liver Neoplasms; Molecular Weight; Neoplasm Proteins; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1985 |
Combination chemotherapy for unresectable hepatoblastoma in children.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Doxorubicin; Female; Fluorouracil; Humans; Infant; Liver Neoplasms; Male; Vincristine | 1987 |
Assessment of hormone action in cultured cells.
Topics: Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Line; Corticosterone; Dactinomycin; Enzyme Induction; Estradiol; Hydrocortisone; Hydroxyprogesterones; Immunoassay; In Vitro Techniques; Insulin; Liver Neoplasms; Neoplasms, Experimental; Rabbits; Rats; Tritium; Tyrosine Transaminase | 1971 |
Effect of various anticancer agents on DNA polymerase.
Topics: Adenosine Triphosphate; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Bleomycin; Bone Marrow; Carcinoma, Hepatocellular; Cytosine Nucleotides; Dactinomycin; Deoxyribonucleotides; DNA Nucleotidyltransferases; DNA, Neoplasm; Fluorouracil; Guanosine Triphosphate; Liver; Liver Neoplasms; Liver Regeneration; Mitomycins; Neoplasms, Experimental; Rats; Rifampin; Thymidine; Tritium | 1971 |
Modified induction of ornithine decarboxylase by factors which affect liver regeneration.
Topics: Adrenal Glands; Adrenalectomy; Age Factors; Animals; Azacitidine; Azaguanine; Carbon Isotopes; Carboxy-Lyases; Carcinoma, Hepatocellular; Cycloheximide; Dactinomycin; DNA; Enzyme Induction; Hepatectomy; Hydrocortisone; Liver; Liver Neoplasms; Liver Regeneration; Male; Ornithine; Rats; Solubility | 1972 |
Repression and derepression of purine biosynthesis in mammalian hepatoma cells in culture.
Topics: Acyltransferases; Adenine; Animals; Azacitidine; Carbon Isotopes; Carcinoma, Hepatocellular; Clone Cells; Cycloheximide; Dactinomycin; Feedback; Formates; Glycine; Kinetics; Ligases; Liver Neoplasms; Neoplasms, Experimental; Pentosephosphates; Pentosyltransferases; Purines; Rats; Ribonucleotides; Ribose; Tetrahydrofolates; Tritium | 1972 |
Synthesis and turnover of RNA in the 30-S nuclear ribonucleoprotein complexes of mouse ascites cells.
Topics: Animals; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Cell Nucleus; Cells, Cultured; Centrifugation, Density Gradient; Dactinomycin; DNA; Isotope Labeling; Kinetics; Liver; Liver Neoplasms; Mice; Neoplasm Proteins; Neoplasms, Experimental; Nucleoproteins; Phosphorus Isotopes; RNA; RNA, Neoplasm; Tritium | 1972 |
[Biosynthesis of proteins characteristic of the regeneration of liver and hepatoma].
Topics: Alpha-Globulins; Animals; Beta-Globulins; Blood Proteins; Carbon Isotopes; Carcinoma, Hepatocellular; Chromatography, DEAE-Cellulose; Dactinomycin; gamma-Globulins; Hepatectomy; Injections, Intraperitoneal; Injections, Subcutaneous; Leucine; Liver Neoplasms; Liver Regeneration; Male; Neoplasm Transplantation; Rats | 1972 |
Single strand scission and repair of DNA in bleomycin-sensitive and resistant rat ascites hepatoma cells.
Topics: Animals; Bleomycin; Carcinoma, Hepatocellular; Cells, Cultured; Centrifugation, Density Gradient; Cycloheximide; Dactinomycin; DNA Repair; DNA, Neoplasm; DNA, Single-Stranded; Drug Resistance; Liver Neoplasms; Neoplasms, Experimental; Rats; Sodium Dodecyl Sulfate; Thymidine; Tritium | 1973 |
Inhibition of ribosomal ribonucleic acid maturation by 5-azacytidine and 8-azaguanine in Novikoff hepatoma cells.
Topics: Animals; Azacitidine; Azaguanine; Carcinoma, Hepatocellular; Cells, Cultured; Cytidine; Dactinomycin; Electrophoresis, Polyacrylamide Gel; Fluorouracil; Guanosine; Isotope Labeling; Liver; Liver Neoplasms; Neoplasms, Experimental; Rats; RNA, Neoplasm; RNA, Ribosomal; Spectrophotometry, Ultraviolet; Time Factors; Tritium; Uridine | 1974 |
Regulation of glutamine synthetase activity of hepatoma tissue culture cells by glutamine and dexamethasone.
Topics: Carbon Radioisotopes; Carcinoma, Hepatocellular; Cells, Cultured; Clone Cells; Cycloheximide; Dactinomycin; Dexamethasone; Dose-Response Relationship, Drug; Enzyme Induction; Fluorides; Glutamate-Ammonia Ligase; Glutamine; Kinetics; Liver Neoplasms; Time Factors; Tyrosine Transaminase | 1973 |
Steroid-induced nuclear binding of glucocorticoid receptors in intact hepatoma cells.
Topics: Animals; Binding Sites; Carcinoma, Hepatocellular; Cell Fractionation; Cell Nucleus; Cells, Cultured; Chromatography, Thin Layer; Corticosterone; Cycloheximide; Cytosol; Dactinomycin; Dexamethasone; Enzyme Induction; Hydrocortisone; Kinetics; Liver; Liver Neoplasms; Progesterone; Rats; Receptors, Cell Surface; Temperature; Time Factors; Tritium; Tyrosine Transaminase | 1973 |
Differential sensitivity of rat liver and rat hepatoma cells to alpha-amanitin.
Topics: Adrenalectomy; Animals; Basidiomycota; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Nucleus; Dactinomycin; DNA-Directed RNA Polymerases; Enzyme Induction; Hydrocortisone; Liver; Liver Neoplasms; Mycotoxins; Nucleotides; Oligopeptides; Orotic Acid; Peptides, Cyclic; Rats; Tritium; Tyrosine Transaminase; Uracil; Uridine | 1973 |
Further evidence against post-transcriptional control of inducible tyrosine aminotransferase synthesis in cultured hepatoma cells.
Topics: Adenosine; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cells, Cultured; Dactinomycin; Deoxyadenosines; Enzyme Induction; Enzyme Repression; Hydrocortisone; Kinetics; Leucine; Liver Neoplasms; RNA, Messenger; RNA, Ribosomal; Transcription, Genetic; Tritium; Tyrosine Transaminase | 1973 |
Transfer ribonucleic acid in hepatoma tissue culture cells. I. Induction in vivo by dexamethasone phosphate of phenylalanine-accepting activity.
Topics: Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Line; Chlorofluorocarbons, Methane; Chromatography; Chromatography, DEAE-Cellulose; Culture Techniques; Dactinomycin; Dexamethasone; Electrophoresis, Paper; Enzyme Induction; Insulin; Kinetics; Liver Neoplasms; Phenylalanine; Receptors, Drug; RNA, Transfer; Tritium; Tyrosine Transaminase; Uridine | 1974 |
Hormonal mechanisms in regulation of gene expression.
Topics: Animals; Antigen-Antibody Reactions; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Line; Cycloheximide; Dactinomycin; Enzyme Induction; Genes; Hydrocortisone; Immunodiffusion; Insulin; Isotope Labeling; Kinetics; Leucine; Liver; Liver Neoplasms; Rats; RNA, Messenger; Time Factors; Tyrosine Transaminase | 1973 |
Regulation of tyrosine aminotrasferase activity in two liver-derived permanent cell lines.
Topics: Animals; Carcinoma, Hepatocellular; Cell Division; Cell Line; Dactinomycin; Demecolcine; Dexamethasone; Enzyme Induction; Kinetics; Liver; Liver Neoplasms; Mitosis; Neoplasms, Experimental; Rats; Time Factors; Tyrosine Transaminase | 1974 |
Hormonal regulation of protein degradation in hepatoma cells in tissue culture.
Topics: Animals; Blood; Carcinoma, Hepatocellular; Cattle; Cells, Cultured; Cycloheximide; Dactinomycin; Dexamethasone; In Vitro Techniques; Insulin; Leucine; Liver Neoplasms; Proteins; Rats; Tritium; Tyrosine Transaminase | 1974 |
Interaction between hormones and cyclic AMP in regulating specific hepatic enzyme synthesis.
Topics: Adrenalectomy; Animals; Bucladesine; Carcinoma, Hepatocellular; Cell Line; Dactinomycin; Dexamethasone; Drug Interactions; Enzyme Induction; Glycogen; Insulin; Liver; Liver Neoplasms; Neoplasms, Experimental; Phosphoenolpyruvate Carboxykinase (GTP); Progesterone; Rats; Stimulation, Chemical; Tyrosine Transaminase | 1974 |
Stimulation of enzyme synthesis and inhibition of DNA synthesis and growth rate by cyclic AMP derivatives in cultured hepatoma cells.
Topics: Animals; Bucladesine; Carcinoma, Hepatocellular; Cell Line; Culture Techniques; Cyclic AMP; Dactinomycin; Dexamethasone; DNA, Neoplasm; Growth; Immunodiffusion; Insulin; Kinetics; Liver; Liver Neoplasms; Mitosis; Phosphoenolpyruvate Carboxykinase (GTP); Rats; Tyrosine Transaminase | 1973 |
The role of messenger RNA in tyrosine aminotransferase superinduction: effects of camptothecin on hepatoma cells in culture.
Topics: Animals; Camptothecin; Carcinoma, Hepatocellular; Cells, Cultured; Dactinomycin; Deoxyadenosines; Enzyme Induction; Hydrocortisone; Insulin; Liver; Liver Neoplasms; Neoplasms, Experimental; Protein Biosynthesis; Rats; RNA, Messenger; Time Factors; Tyrosine Transaminase | 1974 |
Effect of growth conditions on the activity of ornithine decarboxylase in cultured hepatoma cells. II. Effect of serum and insulin.
Topics: Animals; Carboxy-Lyases; Carcinoma, Hepatocellular; Cattle; Dactinomycin; Immune Sera; Insulin; Liver Neoplasms; Ornithine; Rats; Stimulation, Chemical; Time Factors; Tyrosine Transaminase | 1974 |
Inhibition of messenger RNA accumulation but not translation in ultraviolet irradiated hepatoma cells.
Topics: Animals; Carcinoma, Hepatocellular; Cell Line; Dactinomycin; DNA, Neoplasm; Dose-Response Relationship, Radiation; Enzyme Induction; Hydrocortisone; Insulin; Leucine; Liver Neoplasms; Neoplasm Proteins; Neoplasms, Experimental; Protein Biosynthesis; Radiation Effects; Rats; RNA, Messenger; RNA, Neoplasm; Spectrophotometry, Ultraviolet; Thymidine; Time Factors; Transcription, Genetic; Tritium; Tyrosine Transaminase; Ultraviolet Rays; Uridine | 1974 |
Induction of aryl hydrocarbon (benzo(a)pyrene) hydroxylase and tyrosine aminotransferase in hepatoma cells in culture.
Topics: Animals; Benz(a)Anthracenes; Benzopyrenes; Carcinoma, Hepatocellular; Cell Line; Cycloheximide; Dactinomycin; Deoxyadenosines; Dexamethasone; Drug Synergism; Enzyme Induction; Leucine; Liver Neoplasms; Microsomes; Mixed Function Oxygenases; Neoplasm Proteins; Protein Biosynthesis; Rats; RNA, Neoplasm; Spectrophotometry; Transcription, Genetic; Tritium; Tyrosine Transaminase; Uridine | 1974 |
Induction of tyrosine aminotransferase by Sepharose-insulin.
Topics: Animals; Binding Sites; Carcinoma, Hepatocellular; Cell Line; Dactinomycin; Dexamethasone; Enzyme Induction; Freeze Drying; Insulin; Kinetics; Liver Neoplasms; Macromolecular Substances; Polysaccharides; Protein Binding; Rats; Sepharose; Swine; Time Factors; Tyrosine Transaminase | 1974 |
Mengovirus replication in Novikoff rat hepatoma and mouse L cells: effects on synthesis of host-cell macromolecules and virus-specific synthesis of ribonucleic acid.
Topics: Animals; Carcinoma, Hepatocellular; Culture Techniques; Dactinomycin; Encephalomyocarditis virus; L Cells; Liver Neoplasms; Mice; Neoplasm Proteins; Neoplasms, Experimental; Proteins; RNA; RNA Nucleotidyltransferases; RNA, Neoplasm; RNA, Viral; Virus Diseases; Virus Replication | 1968 |
Malignant hepatoma in the Bantu.
Topics: Adenoma, Bile Duct; Africa, Eastern; Alanine Transaminase; Antineoplastic Agents; Aspartate Aminotransferases; Black People; Blood Proteins; Carcinoma, Hepatocellular; Clinical Enzyme Tests; Cyclophosphamide; Cytarabine; Dactinomycin; Fluorouracil; gamma-Globulins; Humans; Hydroxyurea; Liver Neoplasms; Male; Mercaptopurine; Methotrexate; Mitomycins; Nitrogen Mustard Compounds; Prednisone; Prognosis; South Africa; Vincristine | 1970 |
Synthesis of the ninth component of complement by a clonal strain of rat hepatoma cells.
Topics: Animals; Carcinoma, Hepatocellular; Centrifugation, Density Gradient; Clone Cells; Complement System Proteins; Culture Media; Culture Techniques; Cycloheximide; Dactinomycin; Hemolysis; Hydrocortisone; Liver Neoplasms; Neoplasms, Experimental; Protein Biosynthesis; Rats; RNA; Temperature | 1970 |
The interaction of external and internal controls on enzyme levels and hepatoma.
Topics: Animals; Carcinoma, Hepatocellular; Cortisone; Dactinomycin; Endoplasmic Reticulum; Glucagon; Hydro-Lyases; Liver; Liver Neoplasms; Molecular Biology; Transaminases; Tryptophan Oxygenase | 1965 |
Polyribosomes in rat tissues. IV. On the abnormal dimer peak in hepatomas.
Topics: Animals; Carbon Isotopes; Carbon Tetrachloride; Carcinoma, Hepatocellular; Dactinomycin; In Vitro Techniques; Leucine; Liver Neoplasms; Neoplasms, Experimental; Rats; Ribosomes; RNA, Messenger; Temperature; Ultracentrifugation | 1966 |
Replication of mengovirus. I. Effect on synthesis of macromolecules by host cell.
Topics: Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Culture Techniques; Dactinomycin; DNA; Encephalomyocarditis virus; Liver Neoplasms; Neoplasms, Experimental; Protein Biosynthesis; Rats; Ribonucleases; RNA; RNA, Viral; Ultracentrifugation; Viral Interference | 1966 |
Polyribosome breakdown in rat liver following administration of 8-azaguanine.
Topics: Animals; Azaguanine; Carbon Isotopes; Carcinoma, Hepatocellular; Dactinomycin; Liver; Liver Neoplasms; Male; Neoplasms, Experimental; Orotic Acid; Rats; Ribosomes; RNA, Messenger | 1967 |
Priming activity for RNA synthesis of chromatin from transplantable hepatomas and livers of tumor-bearing rats.
Topics: Animals; Carcinoma, Hepatocellular; Chromosomes; Dactinomycin; Liver; Liver Neoplasms; Male; Neoplasm Transplantation; Neoplasms, Experimental; Quaternary Ammonium Compounds; Rats; RNA, Neoplasm | 1967 |
On the mechanism of phenethyl alcohol-induced loss of polyribosomes and their re-formation after reversal in rat hepatoma cells.
Topics: Amino Acids; Animals; Antineoplastic Agents; Carbon Isotopes; Carcinoma, Hepatocellular; Centrifugation, Density Gradient; Culture Techniques; Cycloheximide; Dactinomycin; Ethanol; Liver Neoplasms; Neoplasm Proteins; Neoplasms, Experimental; Rats; Ribosomes; RNA, Messenger; Spectrophotometry; Time Factors; Tritium; Uridine | 1968 |
Choline metabolism and membrane formation in rat hepatoma cells grown in suspension culture. I. Incorporation of choline into phosphatidylcholine of mitochondria and other membranous structures and effect of metabolic inhibitors.
Topics: Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Membrane; Centrifugation, Density Gradient; Chloramphenicol; Choline; Chromatography, Thin Layer; Culture Techniques; Cycloheximide; Dactinomycin; Dihydrolipoamide Dehydrogenase; Electron Transport Complex IV; Glucose-6-Phosphatase; Liver Neoplasms; Malate Dehydrogenase; Microscopy, Electron; Mitochondria; Phosphatidylcholines; Puromycin; Rats; Tritium; Uridine | 1968 |
Diversity and nature of ribosomal pools in hepatoma 7800 and host liver.
Topics: Animals; Azaguanine; Carbon Isotopes; Carbon Tetrachloride; Carcinoma, Hepatocellular; Dactinomycin; Ferritins; Liver; Liver Neoplasms; Neoplasms, Experimental; Orotic Acid; Puromycin; Rats; Ribosomes | 1968 |
Two deoxyribonucleases from Novifoff ascites hepatoma cells.
Topics: Animals; Antibiotics, Antineoplastic; Carcinoma, Hepatocellular; Chromatography; Dactinomycin; Deoxyribonucleases; Edetic Acid; Heparin; Hydrogen-Ion Concentration; Liver Neoplasms; Magnesium; Neoplasms, Experimental; Phosphoric Monoester Hydrolases; Rats; Sulfhydryl Compounds; Temperature | 1968 |
Hepatoblastoma and hepatoma in infancy and childhood. Light and electron microscopic studies.
Topics: Carcinoma, Hepatocellular; Cell Nucleus; Child; Child, Preschool; Cyclophosphamide; Cytoplasmic Granules; Dactinomycin; Endoplasmic Reticulum; Female; Golgi Apparatus; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Liver Neoplasms; Male; Microscopy; Microscopy, Electron; Mitochondria, Liver; Vincristine | 1969 |
Effects of actinomycin D on the oligonucleotide composition of nucleolar 45-S RNA of Novikoff hepatoma ascites cells.
Topics: Adenine Nucleotides; Animals; Carcinoma, Hepatocellular; Cell Nucleolus; Centrifugation, Density Gradient; Cytosine Nucleotides; Dactinomycin; Depression, Chemical; Guanine Nucleotides; Hydrogen-Ion Concentration; Liver Neoplasms; Male; Neoplasms, Experimental; Nucleotides; Phosphates; Phosphorus Isotopes; Rats; Ribonucleases; RNA; Solubility; Spectrophotometry; Uracil Nucleotides | 1969 |
Hormonal effect on nucleolar RNA polymerase in normal liver and hepatoma cells.
Topics: Animals; Carcinoma, Hepatocellular; Cell Nucleolus; Dactinomycin; Estradiol; Estrogens; Glucocorticoids; Hydrocortisone; Liver; Liver Neoplasms; Neoplasms, Experimental; Nucleotidyltransferases; Prednisolone; Rats; RNA, Neoplasm | 1968 |
Antitumor effect of actinomycin-D on transplantable Wilms tumor in rats.
Topics: Animals; Ascites; Carcinoma, Hepatocellular; Dactinomycin; Injections, Intraperitoneal; Injections, Subcutaneous; Liver Neoplasms; Neoplasm Transplantation; Neoplasms, Experimental; Rats; Wilms Tumor | 1968 |
Relationship between uridine kinase activity and rate of incorporation of uridine into acid-soluble pool and into RNA during growth cycle of rat hepatoma cells.
Topics: Animals; Carcinoma, Hepatocellular; Cell-Free System; Chromatography, Paper; Culture Media; Culture Techniques; Cycloheximide; Dactinomycin; Depression, Chemical; Electrophoresis; Liver Neoplasms; Mitosis; Neoplasms, Experimental; Phosphotransferases; Proteins; Puromycin; RNA, Neoplasm; Tritium; Uridine | 1969 |
Liver irradiation in children: acute changes with transient leukopenia and thrombocytopenia.
Topics: Carcinoma, Hepatocellular; Child; Child, Preschool; Dactinomycin; Female; Hepatectomy; Hepatitis A; Humans; Infant; Kidney Neoplasms; Leukopenia; Liver; Liver Function Tests; Liver Neoplasms; Male; Radiation Injuries; Radionuclide Imaging; Radiotherapy Dosage; Thrombocytopenia; Vincristine; Wilms Tumor | 1969 |
[Electron microscopic cytochemistry of the nucleus and the nucleolus].
Topics: Aflatoxins; Animals; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Cell Nucleolus; Cell Nucleus; Dactinomycin; Histocytochemistry; Liver; Liver Neoplasms; Microscopy, Electron; Rats; Ribosomes | 1969 |
Increase of glycogen and oligosaccharide contents in ascites tumor cells under the influence of alkylating agents.
Topics: Alkylating Agents; Animals; Antineoplastic Agents; Ascites; Carcinoma, Hepatocellular; Cobalt Isotopes; Colchicine; Cyclophosphamide; Dactinomycin; Female; Glycogen; Liver Neoplasms; Mechlorethamine; Mercaptopurine; Mitomycins; Neoplasm Transplantation; Neoplasms, Experimental; Oligosaccharides; Rats; Sarcoma, Yoshida | 1969 |
Induction of glutamine synthetase by cortisol.
Topics: Adrenal Glands; Adrenalectomy; Ammonia; Aniline Compounds; Animals; Azo Compounds; Carcinoma 256, Walker; Carcinoma, Hepatocellular; Dactinomycin; Depression, Chemical; Dietary Proteins; Enzyme Induction; Glutamine; Hydrocortisone; Ligases; Liver; Liver Neoplasms; Lymphoma, Non-Hodgkin; Male; Neoplasm Transplantation; Neoplasms, Experimental; p-Dimethylaminoazobenzene; Rats; Starvation; Stimulation, Chemical; Time Factors | 1968 |
Competitive inhibition of uridine incorporation by 6-azauridine in uninfected and mengovirus-infected Novikoff hepatoma cells.
Topics: Adenine Nucleotides; Animals; Carcinoma, Hepatocellular; Cell Line; Chromatography, Paper; Culture Techniques; Dactinomycin; Encephalomyocarditis virus; Kinetics; Liver Neoplasms; Methods; Oxidative Phosphorylation; Rats; RNA Nucleotidyltransferases; RNA, Viral; Time; Triazines; Tritium; Uridine; Virus Replication | 1969 |
[Electron microscope localization of the activity of certain nucleases in ultrathin serial sections].
Topics: Acid Phosphatase; Alkaline Phosphatase; Animals; Carcinoma, Hepatocellular; Cell Nucleus; Dactinomycin; Deoxyribonucleases; Histocytochemistry; In Vitro Techniques; Kidney; Liver; Liver Neoplasms; Membranes; Methods; Microscopy, Electron; Neoplasms, Experimental; Pancreas; Polyvinyls; Rats; Ribonucleases; Sex Chromatin | 1970 |
Benzpyrene hydroxylase activity and its induction by methylcholanthrene in Morris hepatomas, in host livers, in adult livers, and in rat liver during development.
Topics: Animals; Benzopyrenes; Carcinoma, Hepatocellular; Cycloheximide; Dactinomycin; Enzyme Induction; Female; Liver; Liver Neoplasms; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Neoplasms, Experimental; Puromycin; Rats | 1970 |
Studies on the mechanism of template stability: cytoplasmic DNA-like RNA in hepatocellular carcinomas.
Topics: Adenine Nucleotides; Animals; Carcinoma, Hepatocellular; Cell Membrane; Centrifugation, Density Gradient; Cytoplasm; Dactinomycin; DNA; DNA, Neoplasm; Female; Liver Neoplasms; Male; Microscopy, Electron; Microsomes; Neoplasms, Experimental; Phosphorus Isotopes; Rats; RNA; RNA, Neoplasm; Templates, Genetic | 1970 |
Responsiveness of glutamine-metabolizing enzymes in Morris hepatomas to metabolic modulations.
Topics: Adrenalectomy; Animal Feed; Animals; Animals, Laboratory; Carcinoma, Hepatocellular; Cell Line; Chromosomes; Dactinomycin; Dietary Proteins; Enzyme Activation; Glutaminase; Glutamine; Hydrocortisone; Ligases; Liver Neoplasms; Neoplasm Transplantation; Neoplasms, Experimental; Rats; Thyroxine; Transaminases; Transplantation, Homologous | 1970 |
Effect of mengovirus replication on choline metabolism and membrane formation in novikoff hepatoma cells.
Topics: Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Membrane; Centrifugation, Density Gradient; Choline; Chromatography, Thin Layer; Culture Techniques; Cytoplasm; Dactinomycin; Encephalomyocarditis virus; Guanine Nucleotides; Lipids; Liver Neoplasms; Microscopy, Electron; Phosphatidylcholines; Puromycin; Rats; RNA Nucleotidyltransferases; RNA, Viral; Sucrose; Time Factors; Tritium; Uridine; Virus Replication | 1970 |
[Actinomycin D binding with the DNA of some transplantable tumors].
Topics: Animals; Carcinoma, Hepatocellular; Dactinomycin; DNA; DNA, Neoplasm; Liver; Liver Neoplasms; Lymphoma, Non-Hodgkin; Mice; Neoplasms, Experimental; Rats; Thymus Gland | 1971 |
Behavior of opposing pathways of thymidine utilization in differentiating, regenerating, and neoplastic liver.
Topics: Animals; Animals, Newborn; Carbon Dioxide; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Differentiation; Culture Techniques; Dactinomycin; DNA; DNA Replication; DNA, Neoplasm; Hepatectomy; Liver; Liver Neoplasms; Liver Regeneration; Male; Neoplasms, Experimental; Rats; Thymidine | 1971 |
Glucocorticoid-induced alteration of the surface membrane of cultured hepatoma cells.
Topics: Agglutination Tests; Amnion; Animals; Bone Marrow; Carcinoma, Hepatocellular; Cell Adhesion; Cell Line; Cell Membrane; Clone Cells; Cricetinae; Culture Media; Culture Techniques; Cycloheximide; Dactinomycin; Dexamethasone; Dinitrophenols; Edetic Acid; Glass; Half-Life; HeLa Cells; Histocytochemistry; Humans; Hydrogen-Ion Concentration; Laryngeal Neoplasms; Liver Neoplasms; Methods; Microscopy, Phase-Contrast; Proteins; RNA; Temperature; Time Factors | 1970 |
[In vitro cytotoxic effects of antineoplastic agents on malignant tumor cells derived from children].
Topics: Carcinoma, Hepatocellular; Child, Preschool; Cyclophosphamide; Dactinomycin; Daunorubicin; Female; Humans; In Vitro Techniques; Infant; Liver Neoplasms; Male; Neuroblastoma; Vincristine; Wilms Tumor | 1971 |
Liver tumours in infancy and childhood.
Topics: Adolescent; Carcinoma, Hepatocellular; Child; Child, Preschool; Cyclophosphamide; Dactinomycin; Female; Hamartoma; Hepatectomy; Humans; Infant; Infant, Newborn; Liver Neoplasms; Male; Mesenchymoma; Methotrexate; Rhabdomyosarcoma; Vincristine | 1971 |
Mechanisms in cellular metabolic regulation.
Topics: Animals; Animals, Newborn; Carcinoma, Hepatocellular; Cortisone; Dactinomycin; Diabetes Mellitus, Experimental; Diet; Fasting; Glucagon; Hydro-Lyases; Isoenzymes; L-Serine Dehydratase; Leucine; Liver; Liver Neoplasms; Models, Biological; Molecular Biology; Neoplasms, Experimental; Rats; RNA, Messenger; Tritium | 1971 |
Studies on rat liver catalase. V. Incorporation of 14 C-leucine into catalase by isolated rat liver ribosomes.
Topics: Acetamides; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Catalase; Cell-Free System; Cycloheximide; Dactinomycin; Depression, Chemical; In Vitro Techniques; Leucine; Liver; Liver Neoplasms; Male; Neoplasms, Experimental; Nucleotides; Puromycin; Rats; Ribonucleases; Ribosomes; Triazoles | 1971 |
Association of exogenous RNA with Novikoff hepatoma ascites cells.
Topics: Animals; Ascites; Autoradiography; Carcinoma, Hepatocellular; Cell Fractionation; Centrifugation, Density Gradient; Cytosine Nucleotides; Dactinomycin; Dextrans; Electrophoresis, Disc; Guanosine; Liver Neoplasms; Methods; Neoplasm Transplantation; Neoplasms, Experimental; Nucleotides; Phosphorus Isotopes; Rats; Rats, Inbred Strains; Ribonucleases; RNA; Time Factors | 1972 |
Hormonal modulation of amino acid transport in rat hepatoma cells in tissue culture.
Topics: Amino Acids; Aminoisobutyric Acids; Animals; Biological Transport, Active; Carbon Isotopes; Carcinoma, Hepatocellular; Clone Cells; Culture Media; Cycloheximide; Dactinomycin; Depression, Chemical; Dexamethasone; Diffusion; Drug Synergism; Insulin; Kinetics; Liver Neoplasms; Neoplasm Proteins; Rats; Stimulation, Chemical; Swine; Time Factors | 1973 |
Sexual precocity attributable to ectopic gonadotropin secretion by hepatoblastoma.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Carcinoma, Hepatocellular; Child, Preschool; Dactinomycin; Estrogens; Ethinyl Estradiol; Gonadotropins; Hormones, Ectopic; Humans; Liver; Liver Neoplasms; Luteinizing Hormone; Male; Neutralization Tests; Puberty, Precocious; Testosterone | 1973 |
Effect of phleomycin on the replication of mengovirus in novikoff hepatoma cells.
Topics: Amino Acids; Animals; Antibiotics, Antineoplastic; Carcinoma, Hepatocellular; Cell Line; Dactinomycin; DNA-Directed RNA Polymerases; Enzyme Induction; Liver Neoplasms; Mengovirus; Neoplasm Proteins; Peptides; Rats; RNA, Neoplasm; RNA, Viral; Time Factors; Tritium; Uridine; Viral Proteins; Virus Replication | 1973 |
Influence of hormones on the growth of hepatomas and induction of adenylate and pyruvate kinases.
Topics: Adenine; Adrenal Glands; Adrenalectomy; Animals; Carcinoma, Hepatocellular; Dactinomycin; Diabetes Mellitus, Experimental; Diet; Enzyme Induction; Fasting; Glucose; Hydrocortisone; Insulin; Liver; Liver Neoplasms; Male; Phosphotransferases; Pyruvate Kinase; Rats; Time Factors | 1973 |
Modified hormonal control of enzymatic activity in tumors.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Adrenalectomy; Animals; Carcinoma, Hepatocellular; Castration; Dactinomycin; Diabetes Mellitus, Experimental; Diet; Dietary Carbohydrates; Estradiol; Fasting; Female; Glucosephosphate Dehydrogenase; Gonadal Steroid Hormones; Hydrocortisone; Insulin, Long-Acting; Liver; Liver Neoplasms; Neoplasm Transplantation; Neoplasms, Experimental; Ovary; Phosphotransferases; Progesterone; Pyruvate Kinase; Rats; Testosterone | 1973 |
The induction of ornithine decarboxylase in cultured hepatoma cells.
Topics: Animals; Carboxy-Lyases; Carcinoma, Hepatocellular; Culture Techniques; Dactinomycin; Enzyme Induction; Half-Life; Liver Neoplasms; Neoplasms, Experimental; Ornithine; Rats | 1972 |
Effect of actinomycin D on uptake and incorporation of thymidine and hypoxanthine into the acid-soluble and acid-insoluble fractions of rat hepatoma cells grown in culture.
Topics: Animals; Carcinoma, Hepatocellular; Cells, Cultured; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Hypoxanthines; Kinetics; Liver Neoplasms; Neoplasms, Experimental; Rats; Stimulation, Chemical; Thymidine; Thymidine Kinase; Time Factors; Tritium; Uridine | 1974 |
Effect of uridine on de novo pyrimidine biosynthesis in rat hepatoma cells in culture.
Topics: Amidohydrolases; Animals; Aspartate Carbamoyltransferase; Carbamates; Carbon Dioxide; Carbon Radioisotopes; Carboxy-Lyases; Carcinoma, Hepatocellular; Clone Cells; Cycloheximide; Dactinomycin; DNA, Neoplasm; Glutamine; Kinetics; Liver Neoplasms; Neoplasms, Experimental; Orotic Acid; Pentosyltransferases; Phosphotransferases; Pyrimidine Nucleotides; Rats; Ribonucleotides; RNA, Neoplasm; Uridine | 1974 |
Electrophoretic characterization of shuttling and nonshuttling small nuclear RNAs.
Topics: Amoeba; Animals; Autoradiography; Carcinoma, Hepatocellular; Cell Line; Cell Nucleus; Chromatin; Cytoplasm; Dactinomycin; Densitometry; Electrophoresis, Polyacrylamide Gel; Liver Neoplasms; Molecular Weight; Phosphorus Radioisotopes; Rats; RNA; RNA, Neoplasm; Transcription, Genetic | 1974 |
Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in hepatoma tissue culture cells by serum lipoproteins.
Topics: Alcohol Oxidoreductases; Animals; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cattle; Cell Line; Chromatography, Thin Layer; Coenzyme A; Culture Media; Cycloheximide; Dactinomycin; Enzyme Activation; Glutarates; Half-Life; Kinetics; Lipoproteins; Liver Neoplasms; Mevalonic Acid; Microsomes; Neoplasms, Experimental; Rats; Time Factors; Tritium; Ultracentrifugation | 1974 |
Effect of metabolic inhibitors on killing of tumor cells by antibody and complement.
Topics: Animals; Antigen-Antibody Reactions; Antimetabolites; Carcinoma, Hepatocellular; Cell Line; Complement System Proteins; Cytotoxicity Tests, Immunologic; Dactinomycin; Guinea Pigs; Hydroxyurea; Liver Neoplasms; Mitomycins; Neoplasms, Experimental; Puromycin; Rabbits; Stimulation, Chemical | 1974 |
Acinomycin D and purine transport in cultured rat hepatoma cells.
Topics: Adenine; Animals; Biological Transport, Active; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cells, Cultured; Clone Cells; Culture Media; Cycloheximide; Dactinomycin; Guanine; Guanosine; Hypoxanthines; Kinetics; Liver Neoplasms; Neoplasms, Experimental; Pentosyltransferases; Purines; Rats | 1974 |
Release of cytoplasmic enzymes into culture fluid.
Topics: Acid Phosphatase; Alkaline Phosphatase; Animals; Carcinoma, Hepatocellular; Cell Fractionation; Cells, Cultured; Cycloheximide; Dactinomycin; Deoxyribonucleases; Fibroblasts; Glucuronidase; HeLa Cells; Humans; Liver; Liver Neoplasms; Mice; Neoplasms, Experimental; Rats; Ribonucleases | 1974 |
Template stability of some enzymes in rat liver and hepatoma.
Topics: Animals; Carcinoma, Hepatocellular; Caseins; Dactinomycin; Hydro-Lyases; In Vitro Techniques; Liver; Liver Neoplasms; Rats; Serine; Subcellular Fractions; Transaminases; Tyrosine Transaminase | 1965 |
Induction of tyrosine alpha-ketoglutarate transaminase by steroid hormones in a newly established tissue culture cell line.
Topics: Aldosterone; Animals; Carcinoma, Hepatocellular; Culture Techniques; Cycloheximide; Dactinomycin; Desoxycorticosterone; Dexamethasone; Diethylstilbestrol; Enzyme Induction; Estradiol; Hydrocortisone; Leucine; Liver Neoplasms; Mitomycins; Progesterone; Puromycin; Rats; Steroids; Testosterone; Transaminases; Triamcinolone; Tyrosine Transaminase | 1966 |
"Superinduction" of tyrosine transaminase in hepatoma cell cultures: differential inhibition of synthesis and turnover by actionomycin D.
Topics: Carbon Isotopes; Carcinoma, Hepatocellular; Culture Techniques; Dactinomycin; Enzyme Induction; Hydrocortisone; Immunoassay; Leucine; Liver Neoplasms; RNA, Messenger; Tritium; Tyrosine Transaminase | 1968 |
Induction of tyrosine aminotransferase by D-glucosamine in rat hepatoma cell culture.
Topics: Animals; Carcinoma, Hepatocellular; Culture Media; Culture Techniques; Cycloheximide; Dactinomycin; DNA; Enzyme Induction; Glucosamine; Glucose; Liver Neoplasms; Proteins; Rats; Tyrosine Transaminase; Ultrasonics | 1969 |
Control of specific gene expression examined in synchronized mammalian cells.
Topics: Animals; Carcinoma, Hepatocellular; Culture Techniques; Cycloheximide; Dactinomycin; Dexamethasone; Enzyme Induction; Enzyme Repression; Genes, Regulator; Genetic Code; Liver Neoplasms; Mitosis; Neoplasms, Experimental; Rats; Time; Tyrosine Transaminase | 1969 |
Control of tyrosine aminotransferase synthesis in tissue culture by a factor in serum.
Topics: Blood Proteins; Carcinoma, Hepatocellular; Clone Cells; Culture Media; Dactinomycin; Dexamethasone; Enzyme Induction; Liver Neoplasms; Neoplasms, Experimental; Radioimmunoassay; Tyrosine Transaminase | 1969 |
Control of degradation and synthesis of induced tyrosine aminotransferase studied in hepatoma cells in culture.
Topics: Carcinoma, Hepatocellular; Culture Media; Culture Techniques; Cycloheximide; Dactinomycin; Enzyme Induction; Hydrocortisone; Leucine; Liver Neoplasms; Neoplasms, Experimental; Tritium; Tyrosine Transaminase | 1969 |
Posttranscriptional control of tyrosine aminotransferase synthesis by insulin.
Topics: Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Cattle; Cell Line; Culture Media; Culture Techniques; Cycloheximide; Dactinomycin; Dexamethasone; Genetic Code; Insulin; Liver Neoplasms; Rats; Serum Albumin, Bovine; Tyrosine Transaminase | 1970 |
Regulation of tyrosine alpha-ketoglutarate transaminase in rat liver. IX. Studies of the mechanisms of hormonal inductions in cultured hepatoma cells.
Topics: Animals; Carcinoma, Hepatocellular; Cell Line; Culture Techniques; Dactinomycin; Enzyme Induction; Hydrocortisone; Insulin; Kinetics; Liver Neoplasms; Mathematics; Metabolism; Models, Biological; Rats; RNA, Messenger; Tyrosine Transaminase | 1970 |
Superinduction of tyrosine aminotransferase by actinomycin D in rat hepatoma (HTC) cells.
Topics: Animals; Antibodies; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Line; Culture Techniques; Dactinomycin; DNA; Enzyme Induction; Hydroxyurea; Liver Neoplasms; Mitomycins; Nucleosides; Rats; RNA; Thymidine; Tyrosine Transaminase; Uridine; Vibration | 1970 |
Induction of tyrosine aminotransferase by dibutyryl cyclic-AMP employing hepatoma cells in tissue culture.
Topics: Adenine Nucleotides; Carcinoma, Hepatocellular; Cell Line; Culture Media; Culture Techniques; Cyclic AMP; Cycloheximide; Dactinomycin; Enzyme Induction; Glucagon; Hydrocortisone; Insulin; Liver Neoplasms; RNA, Messenger; RNA, Neoplasm; Time Factors; Tyrosine Transaminase | 1971 |
Tyrosine transaminase induction: differential effect of 5-azacytidine on liver and hepatoma 5123D.
Topics: Adrenalectomy; Animals; Carbon Isotopes; Carboxy-Lyases; Carcinoma, Hepatocellular; Dactinomycin; Enzyme Induction; Hindlimb; Hydrocortisone; Kinetics; Leucine; Liver; Liver Neoplasms; Macromolecular Substances; Male; Neoplasm Transplantation; Neoplasms, Experimental; Nucleosides; Ornithine; Protein Biosynthesis; Rats; Ribosomes; Sodium Chloride; Tyrosine Transaminase | 1971 |
The regulation of tyrosine aminotransferase synthesis. Studies in HTC cells with inhibitors of ribonucleic acid synthesis.
Topics: Benzimidazoles; Carcinoma, Hepatocellular; Cell Line; Cells, Cultured; Cycloheximide; Dactinomycin; Dexamethasone; Drug Antagonism; Kinetics; Leucine; Liver Neoplasms; Metabolism; Neoplasm Proteins; Phosphates; Phosphorus Isotopes; Pyridines; RNA, Neoplasm; Sulfhydryl Compounds; Templates, Genetic; Tritium; Tyrosine Transaminase; Uridine | 1971 |
Expression of differentiated functions in hepatoma cell hybrids: reappearance of tyrosine aminotransferase inducibility after the loss of chromosomes.
Topics: Animals; Carcinoma, Hepatocellular; Cell Fusion; Cell Line; Cells, Cultured; Chromosomes; Clone Cells; Crosses, Genetic; Cycloheximide; Dactinomycin; Depression, Chemical; Dexamethasone; Enzyme Activation; Enzyme Induction; Epithelial Cells; Epithelium; Hot Temperature; Hybrid Cells; In Vitro Techniques; Karyotyping; Liver; Liver Neoplasms; Rats; Tyrosine Transaminase | 1971 |
Regulation of tyrosine- -ketoglutarate transaminase in rat liver.
Topics: Animals; Carcinoma, Hepatocellular; Cells, Cultured; Cycloheximide; Dactinomycin; Enzyme Induction; Fluorine; Half-Life; Hydrocortisone; Immunodiffusion; Insulin; Keto Acids; Kinetics; Leucine; Liver Neoplasms; Rats; Serine; Stereoisomerism; Tritium; Tyrosine Transaminase | 1971 |
D-glucose suppression of tyrosine aminotransferase in rat-hepatoma cells grown in culture.
Topics: Animals; Carcinoma, Hepatocellular; Cells, Cultured; Culture Media; Cycloheximide; Dactinomycin; Enzyme Induction; Glucosamine; Glucose; Hexoses; In Vitro Techniques; Lactose; Liver Neoplasms; Mannitol; Rats; Stereoisomerism; Tyrosine; Tyrosine Transaminase | 1971 |
Induction of tyrosine aminotransferase with N 6 ,O 2 -dibutyryl adenosine 3'-5'monophosphate in rat-hepatoma cells grown in culture.
Topics: Animals; Butyrates; Carcinoma, Hepatocellular; Cells, Cultured; Culture Media; Cyclic AMP; Cycloheximide; Dactinomycin; Enzyme Induction; Glucose; Hydrocortisone; In Vitro Techniques; Liver Neoplasms; Rats; Tyrosine; Tyrosine Transaminase | 1971 |
Effect of growth conditions on the ornithine decarboxylase activity of rat hepatoma cells.
Topics: Animals; Carbon Isotopes; Carboxy-Lyases; Carcinoma, Hepatocellular; Cell Division; Cell Line; Cycloheximide; Dactinomycin; Liver Neoplasms; Ornithine; Rats; Tyrosine Transaminase | 1971 |
Evidence for translational regulation of specific enzyme synthesis by N 6 , O 2' -dibutyryl cyclic AMP in hepatoma cell cultures.
Topics: Butyrates; Carboxy-Lyases; Carcinoma, Hepatocellular; Cyclic AMP; Dactinomycin; Dexamethasone; Enzyme Induction; Kinetics; Leucine; Liver Neoplasms; Oxaloacetates; Phosphoenolpyruvate; Precipitin Tests; RNA, Neoplasm; Tritium; Tyrosine Transaminase; Uridine | 1972 |
Expression of aryl hydrocarbon hydroxylase induction and suppression of tyrosine aminotransferase induction in somatic-cell hybrids.
Topics: Animals; Antibodies; Antigen-Antibody Reactions; Benz(a)Anthracenes; Carcinoma, Hepatocellular; Cell Line; Cycloheximide; Dactinomycin; Dexamethasone; Enzyme Induction; Fibroblasts; Hybrid Cells; Karyotyping; Kinetics; Liver Neoplasms; Methods; Mice; Mixed Function Oxygenases; Neoplasms, Experimental; Rats; Tyrosine Transaminase | 1972 |
Effect of cordycepin on induction of tyrosine aminotransferase employing hepatoma cells in tissue culture.
Topics: Adenosine Monophosphate; Butyrates; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Fractionation; Cell Line; Cytidine; Dactinomycin; Deoxyadenosines; Enzyme Induction; Hydrocortisone; Insulin; Liver Neoplasms; Methods; Neoplasms, Experimental; RNA; Time Factors; Tyrosine Transaminase | 1972 |
Further evidence for posttranscriptional control of inducible tyrosine aminotransferase synthesis in cultured hepatoma cells.
Topics: Amino Acids; Animals; Carcinoma, Hepatocellular; Cells, Cultured; Dactinomycin; Dexamethasone; Enzyme Induction; Enzyme Repression; Genes, Regulator; Liver Neoplasms; Neoplasm Proteins; Rats; RNA; Transcription, Genetic; Tritium; Tyrosine Transaminase | 1972 |
Degradation of messenger RNA in mammalian cells.
Topics: Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Line; Cycloheximide; Dactinomycin; Depression, Chemical; Enzyme Induction; Half-Life; Hydrocortisone; Leucine; Liver; Liver Neoplasms; Methods; Molecular Biology; Protein Biosynthesis; Puromycin; Radioimmunoassay; Rats; Ribosomes; RNA, Messenger; Time Factors; Tyrosine Transaminase | 1972 |