dactinomycin has been researched along with Astrocytoma, Grade IV in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (32.26) | 18.7374 |
| 1990's | 7 (22.58) | 18.2507 |
| 2000's | 8 (25.81) | 29.6817 |
| 2010's | 2 (6.45) | 24.3611 |
| 2020's | 4 (12.90) | 2.80 |
| Authors | Studies |
|---|---|
| Lee, GH; Lee, SE | 1 |
| Bigger, BW; Dickson, A; Ellison, S; Elvin, M; Forte, G; Karabatsou, K; McBain, C; McCabe, M; Nathan, E; Pandele, A; Parker, H; Taylor, JT; Williams, KJ; Wood, S; Zindy, E | 1 |
| Finocchiaro, G | 1 |
| Lehrer, S; Rheinstein, PH | 1 |
| Cui, H; Dong, Z; Ke, XX; Lei, Q; Yang, L; Yang, R; Yi, L; Zhu, S | 1 |
| Elsir, T; Holmberg Olausson, K; Lindström, MS; Moazemi Goudarzi, K; Nistér, M | 1 |
| Billups, C; Cheshire, PJ; Fouladi, M; Friedman, HS; Houghton, PJ; Leggas, M; Peterson, JK; Stewart, CF; Woo, MH | 1 |
| Murakami, O; Shibahara, S; Takahashi, K; Totsune, K; Udono-Fujimori, R | 1 |
| Handa, Y; Kubota, T; Matsukawa, S; Sato, K; Takeuchi, H; Yao, Y | 1 |
| Esumi, H; Fujisawa, H; Hokari, A; Ogura, T; Weisz, A; Yamashita, J | 1 |
| Kondo, S; Kubo, H; Morimura, T; Nakatsu, S; Takeuchi, J; Yin, D | 1 |
| Kondo, S; Morimura, T; Takeuchi, J; Yin, D | 1 |
| Goldthwait, DA; Mapstone, T; Xiao, H | 1 |
| Hara, E; Sasano, H; Shibahara, S; Suzuki, H; Takahashi, K | 1 |
| Adamis, AP; Amano, S; Beerepoot, LV; Colby, KA; Kim, RY; Kuroki, M; Rohan, RM; Takashima, S; Tolentino, M; Voest, EE; Yeo, KT | 1 |
| de Tribolet, N; Desbaillets, I; Diserens, AC; Hamou, MF; Van Meir, EG | 1 |
| Asai, A; Kirino, T; Kuchino, Y; Narita, Y | 1 |
| Hida, W; Kitamuro, T; Murakami, O; Nakayama, M; Shibahara, S; Shirato, K; Takahashi, K | 1 |
| El-Deiry, WS; Meng, RD | 1 |
| Fujimoto, K; Kato, Y; Kawamoto, T; Makihira, S; Noshiro, M; Shen, M; Teramoto, M; Yan, W | 1 |
| Nakamura, H; Tsuneishi, S; Zhang, WL | 1 |
| Kałuza, J | 1 |
| Radzievskaia, VV; Sokolov, AB; Terent'eva, TG | 1 |
| Birkmayer, GD; Marguth, F; Miller, F | 1 |
| Kaluza, J; Stefanicka-Wiechowa, A | 2 |
| Kajiyama, T; Takahashi, T; Takaki, R; Takeno, Y; Takii, M | 1 |
| Afra, D; Gazsó, LR | 1 |
| Dravid, AR; Duffy, TE; Haglid, K | 1 |
| Crocker, DW; Piro, AJ; Shirley, RL | 1 |
| Marek, K | 1 |
1 trial(s) available for dactinomycin and Astrocytoma, Grade IV
| Article | Year |
|---|---|
[Action of aureolic acid and dactinomycin group antibiotics on human brain tumors in culture].
Topics: Antibiotics, Antineoplastic; Astrocytoma; Brain Neoplasms; Cells, Cultured; Clinical Trials as Topic; Dactinomycin; Drug Evaluation, Preclinical; Drug Tolerance; Glioblastoma; Humans; Meningioma; Olivomycins; Plicamycin; Time Factors | 1978 |
30 other study(ies) available for dactinomycin and Astrocytoma, Grade IV
| Article | Year |
|---|---|
Survival and functional recovery of primary cortical neurons exposed to actinomycin D.
Topics: Animals; Brain Neoplasms; Dactinomycin; Glioblastoma; Mice; Neoplasm Recurrence, Local; Neurons | 2022 |
Actinomycin D downregulates Sox2 and improves survival in preclinical models of recurrent glioblastoma.
Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Child; Dactinomycin; Glioblastoma; Glioma; Humans; Mice; Neoplastic Stem Cells; SOXB1 Transcription Factors | 2020 |
Actinomycin D: a new opening for an old drug.
Topics: Dactinomycin; Glioblastoma; Humans; SOXB1 Transcription Factors | 2020 |
The actinomycin D molecule docks to a hydrophilic section of the SOX2 high-mobility group (HMG) domain.
Topics: Dactinomycin; Glioblastoma; Humans; SOXB1 Transcription Factors | 2021 |
Inhibition of neurotensin receptor 1 induces intrinsic apoptosis via let-7a-3p/Bcl-w axis in glioblastoma.
Topics: 3' Untranslated Regions; Animals; Antibiotics, Antineoplastic; Apoptosis; Apoptosis Regulatory Proteins; Caspase 3; Cell Line, Tumor; Cytochromes c; Dactinomycin; Down-Regulation; Doxorubicin; Drug Resistance, Neoplasm; Female; Gene Knockdown Techniques; Glioblastoma; Humans; Membrane Potential, Mitochondrial; Mice; Mice, Nude; MicroRNAs; Mitochondria; Neoplasm Transplantation; Proto-Oncogene Proteins c-bcl-2; Pyrazoles; Quinolines; Receptors, Neurotensin; RNA, Small Interfering; Up-Regulation | 2017 |
NPM1 histone chaperone is upregulated in glioblastoma to promote cell survival and maintain nucleolar shape.
Topics: Animals; Apoptosis; Astrocytes; Brain Neoplasms; Cell Line, Tumor; Cell Nucleolus; Cell Survival; Dactinomycin; Disease Models, Animal; Gene Expression; Gene Knockdown Techniques; Gene Silencing; Glioblastoma; Histone Chaperones; Humans; Immunohistochemistry; Mice, Knockout; Neoplasm Grading; Neural Stem Cells; Nuclear Proteins; Nucleophosmin; Prognosis; Protein Transport | 2015 |
Relation between Irofulven (MGI-114) systemic exposure and tumor response in human solid tumor xenografts.
Topics: Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Child; Chromatography, High Pressure Liquid; Cyclophosphamide; Dacarbazine; Dactinomycin; Disease-Free Survival; Doxorubicin; Female; Glioblastoma; Glioma; Humans; Medulloblastoma; Mice; Mice, Inbred CBA; Mice, Inbred ICR; Mice, SCID; Neoplasms; Neuroblastoma; Neuroectodermal Tumors, Primitive; Radiation Chimera; Random Allocation; Rhabdoid Tumor; Rhabdomyosarcoma, Embryonal; Sesquiterpenes; Tumor Cells, Cultured; Vincristine; Xenograft Model Antitumor Assays | 2002 |
Suppression of cytokine-induced expression of adrenomedullin and endothelin-1 by dexamethasone in T98G human glioblastoma cells.
Topics: Adrenomedullin; Blotting, Northern; Cell Line, Tumor; Chromatography, High Pressure Liquid; Cycloheximide; Cytokines; Dactinomycin; Dexamethasone; Dose-Response Relationship, Drug; Endothelin-1; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Interferon-gamma; Interleukin-1; Nucleic Acid Synthesis Inhibitors; Peptides; Protein Synthesis Inhibitors; Radioimmunoassay; RNA, Messenger; Tumor Necrosis Factor-alpha | 2003 |
Cell-specific but p53-independent regulation of vascular endothelial growth factor expression by interferons in human glioblastoma cells.
Topics: Blotting, Western; Brain Neoplasms; Cell Line, Tumor; Cycloheximide; Dactinomycin; Enzyme-Linked Immunosorbent Assay; Glioblastoma; Humans; Interferons; Mitogen-Activated Protein Kinases; Neovascularization, Pathologic; Protein Synthesis Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Suppressor Protein p53; Up-Regulation; Vascular Endothelial Growth Factor A | 2006 |
Inducible nitric oxide synthase in a human glioblastoma cell line.
Topics: Amino Acid Oxidoreductases; Amino Acid Sequence; Base Sequence; Blotting, Northern; Blotting, Western; Cycloheximide; Cytokines; Dactinomycin; Enzyme Induction; Gene Expression Regulation, Enzymologic; Glioblastoma; Humans; Interleukin-1; Lipopolysaccharides; Molecular Sequence Data; Nitric Oxide Synthase; RNA, Messenger; Transfection; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1995 |
Combination therapy with cisplatin and nifedipine induces apoptosis in cisplatin-sensitive and cisplatin-resistant human glioblastoma cells.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Calcium; Calcium Channels; Cell Nucleus; Cisplatin; Cycloheximide; Dactinomycin; DNA Damage; DNA, Neoplasm; Drug Resistance; Drug Synergism; Endonucleases; Female; Glioblastoma; Humans; Mice; Mice, Inbred BALB C; Neoplasm Proteins; Neoplasm Transplantation; Nifedipine; Nucleosomes; Tumor Cells, Cultured | 1995 |
Combination therapy with cisplatin and nifedipine inducing apoptosis in multidrug-resistant human glioblastoma cells.
Topics: Apoptosis; Calcium; Cisplatin; Cycloheximide; Dactinomycin; DNA Damage; Drug Resistance, Multiple; Drug Synergism; Endonucleases; Enzyme Activation; Glioblastoma; Humans; Nifedipine; Tumor Cells, Cultured | 1995 |
A search for gli expression in tumors of the central nervous system.
Topics: Central Nervous System Neoplasms; Culture Techniques; Dactinomycin; Gene Expression; Glioblastoma; Humans; Neuroglia; Nucleic Acid Hybridization; Polymerase Chain Reaction; RNA, Messenger; Transcription, Genetic | 1994 |
Expression of heme oxygenase isozyme mRNAs in the human brain and induction of heme oxygenase-1 by nitric oxide donors.
Topics: Cycloheximide; Dactinomycin; Gene Expression Regulation, Enzymologic; Glioblastoma; Heme Oxygenase (Decyclizing); Hemin; Hot Temperature; Humans; Isoenzymes; Neuropeptides; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Protein Synthesis Inhibitors; RNA, Messenger; Time Factors; Tumor Cells, Cultured | 1996 |
Reactive oxygen intermediates increase vascular endothelial growth factor expression in vitro and in vivo.
Topics: Animals; Antioxidants; Cattle; Cells, Cultured; Cycloheximide; Dactinomycin; Endothelial Growth Factors; Enzyme Inhibitors; Gene Expression Regulation, Developmental; Glioblastoma; Half-Life; Humans; Hydrogen Peroxide; Lymphokines; Melanoma; Neovascularization, Pathologic; Neovascularization, Physiologic; Oxygen; Pigment Epithelium of Eye; Rabbits; Rats; Reactive Oxygen Species; Reperfusion; Retina; RNA, Messenger; Superoxides; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1996 |
Regulation of interleukin-8 expression by reduced oxygen pressure in human glioblastoma.
Topics: Animals; Cell Hypoxia; Cobalt; Dactinomycin; Dichlororibofuranosylbenzimidazole; Endothelial Growth Factors; Gene Expression Regulation; Glioblastoma; Humans; Interleukin-8; Lymphokines; Mice; Nucleic Acid Synthesis Inhibitors; Oxidation-Reduction; Oxygen; Response Elements; RNA, Messenger; Transcription Factor AP-1; Transcription, Genetic; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1999 |
Actinomycin D and staurosporine, potent apoptosis inducers in vitro, are potentially effective chemotherapeutic agents against glioblastoma multiforme.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cisplatin; Dactinomycin; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Glioblastoma; Humans; Nimustine; Staurosporine; Tumor Cells, Cultured | 2000 |
Induction of adrenomedullin during hypoxia in cultured human glioblastoma cells.
Topics: Actins; Adrenomedullin; Blotting, Northern; Brain Neoplasms; Cell Hypoxia; Cobalt; Cycloheximide; Dactinomycin; DNA-Binding Proteins; Gene Expression Regulation; Glioblastoma; Humans; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Nuclear Proteins; Nucleic Acid Synthesis Inhibitors; Peptides; Protein Synthesis Inhibitors; Radioimmunoassay; RNA Stability; RNA, Messenger; Transcription Factors; Tumor Cells, Cultured | 2000 |
p53-independent upregulation of KILLER/DR5 TRAIL receptor expression by glucocorticoids and interferon-gamma.
Topics: Antibiotics, Antineoplastic; Apoptosis; Betulinic Acid; Colonic Neoplasms; Dactinomycin; Dexamethasone; DNA-Binding Proteins; Female; Glioblastoma; Glucocorticoids; Humans; Interferon-gamma; Melanoma; Mutation; Naphthoquinones; Ovarian Neoplasms; Pentacyclic Triterpenes; Prednisolone; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor; RNA, Messenger; STAT1 Transcription Factor; Trans-Activators; Triterpenes; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Up-Regulation | 2001 |
Induction of basic helix-loop-helix protein DEC1 (BHLHB2)/Stra13/Sharp2 in response to the cyclic adenosine monophosphate pathway.
Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Chondrocytes; Cyclic AMP; Cycloheximide; Dactinomycin; Dogs; Fibroblasts; Gene Expression; Glioblastoma; HeLa Cells; Helix-Loop-Helix Motifs; Homeodomain Proteins; Humans; Kidney; Lung; Melanoma; Mice; Mice, Inbred BALB C; Parathyroid Hormone; Protein Synthesis Inhibitors; Rabbits; RNA, Messenger; Signal Transduction; Teratocarcinoma | 2001 |
Induction of heat shock proteins and its effects on glial differentiation in rat C6 glioblastoma cells.
Topics: Animals; Blotting, Northern; Blotting, Western; Cell Differentiation; Culture Media; Cyclic AMP; Dactinomycin; Gene Expression; Glial Fibrillary Acidic Protein; Glioblastoma; Heat-Shock Proteins; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Hot Temperature; HSP70 Heat-Shock Proteins; Kinetics; Myelin Proteolipid Protein; Neuroglia; Nucleic Acid Synthesis Inhibitors; Platelet-Derived Growth Factor; Rats; Receptors, Platelet-Derived Growth Factor; RNA, Messenger; Tretinoin; Tumor Cells, Cultured | 2001 |
Lactic dehydrogenase activity in degenerative neoplastic glial cells after actinomycin application in vitro.
Topics: Cells, Cultured; Dactinomycin; Glioblastoma; Humans; L-Lactate Dehydrogenase; Neoplasms, Experimental; Nerve Degeneration | 1979 |
Oncorna-viral information in human glioblastoma.
Topics: Brain Neoplasms; Centrifugation, Density Gradient; Dactinomycin; Glioblastoma; Microscopy, Electron; Microsomes; Molecular Weight; Retroviridae; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; RNA, Viral; Spectrum Analysis; Tritium | 1974 |
The cytotoxic and cytostatic effect of actinomycins C and K on glia-like tumors growing in vitro.
Topics: Astrocytoma; Child, Preschool; Culture Techniques; Dactinomycin; Glioblastoma; Humans; Male; Microscopy, Phase-Contrast | 1967 |
Screening of carcinostatic agents in organ culture.
Topics: Animals; Antibiotics, Antineoplastic; Carcinoma; Cerebellar Neoplasms; Chickens; Culture Techniques; Dactinomycin; DNA; DNA, Neoplasm; Ependymoma; Glioblastoma; Glioma; Humans; Mammary Neoplasms, Experimental; Meningioma; Mitomycins; Rats; Sarcoma; Scalp; Thymidine; Thymoma; Thymus Gland; Tritium | 1968 |
Study on the effect of actinomycins in tissue cultures from human brain tumours.
Topics: Astrocytoma; Brain Neoplasms; Culture Techniques; Dactinomycin; Glioblastoma; Humans; Meningioma; Mitosis | 1969 |
The radiomimetic effect of actinomycin C on tumors of glial origin cultured in vitro.
Topics: Animals; Astrocytoma; Cattle; Chick Embryo; Culture Media; Culture Techniques; Dactinomycin; Glioblastoma; Glioma; Humans; Oligodendroglioma; Radiation; Radiation-Sensitizing Agents | 1970 |
Studies on in vitro RNA synthesis in human brain tumor nuclei.
Topics: Brain Neoplasms; Cell Nucleus; Dactinomycin; Diphosphates; Glioblastoma; Glioma; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Meningioma; Nucleotides; RNA Nucleotidyltransferases; RNA, Neoplasm; Tissue Extracts | 1969 |
Malignant neural elements in a benign cystic teratoma. A case report.
Topics: Adult; Antineoplastic Agents; Bone Marrow Diseases; Cyclophosphamide; Dactinomycin; Dermoid Cyst; Female; Glioblastoma; Humans; Liver Neoplasms; Male; Methotrexate; Neoplasm Metastasis; Ovarian Neoplasms; Radiography; Teratoma; Ureteral Neoplasms; Vincristine | 1971 |
[Trial of cytostatic therapy of malignant brain tumors in adults].
Topics: Adult; Aged; Brain Neoplasms; Dactinomycin; Glioblastoma; Humans; Imides; Middle Aged; Neuritis; Prognosis; Sarcoma; Vinblastine | 1972 |