dactinomycin and Acute Myelogenous Leukemia

dactinomycin has been researched along with Acute Myelogenous Leukemia in 76 studies

Research

Studies (76)

Timeframe	Studies, this research(%)	All Research%
pre-1990	51 (67.11)	18.7374
1990's	10 (13.16)	18.2507
2000's	5 (6.58)	29.6817
2010's	4 (5.26)	24.3611
2020's	6 (7.89)	2.80

Authors

Authors	Studies
Brunetti, L; Cardinali, V; Falini, B; Gionfriddo, I; Marra, A; Martelli, MP; Milano, F; Perriello, VM; Pianigiani, G; Pierangeli, S; Ranieri, R; Sciabolacci, S	1
Bertoli, S; Beziat, G; Bories, P; Delabesse, E; Huguet, F; Largeaud, L; Luquet, I; Récher, C; Rieu, JB; Tavitian, S; Vergez, F	1
Berthier, C; Brunetti, L; Cardinali, V; Ciurnelli, R; de Thé, H; Dorillo, E; Falini, B; Falzetti, F; Gionfriddo, I; Griffin, MJ; Jennings, CE; Martelli, MP; Mezzasoma, F; Milano, F; Pierangeli, S; Ranieri, R; Spinozzi, G; Sportoletti, P; Tiacci, E; Veal, GJ; Venanzi, A; Vetro, C; Wu, HC	1
Ades, L; Bazarbachi, A; Benhenda, S; Bénit, P; Berthier, C; Brunetti, L; Clappier, E; Conte, L; de Thé, H; Dombret, H; Durand, S; El Hajj, H; Espeli, O; Falini, B; Fenaux, P; Gachet, S; Hleihel, R; Ito, K; Itzykson, R; Kroemer, G; Lallemand-Breitenbach, V; Mak, TW; Martelli, MP; Morganti, C; Quentin, S; Raffoux, E; Rérolle, D; Rimsky, S; Rustin, P; Sakamoto, T; Sebert, M; Soulier, J; Souquere, S; Trowbridge, JJ; Wu, C; Wu, HC	1
Abou Dalle, I; Bazarbachi, A	1
Daraskevicius, J; Everatt, V; Maneikis, K; Ringeleviciute, U; Vaitekenaite, V; Zucenka, A	1
Bi, K; Chen, F; Fan, J; Hou, M; Liu, G; Ran, X; Wang, J; Wang, L; Wang, M; Wang, X; Wang, Z; Xu, R; Yang, E; Yang, S; Yu, W; Zhao, H	1
Maherus, EM; Rashidi, A	1
Cao, Z; Gong, BF; Gong, XY; Gu, RX; Li, W; Li, Y; Lin, D; Liu, BC; Liu, KQ; Liu, YT; Mi, YC; Wang, JX; Wang, Y; Wei, H; Wei, SN; Zhang, GJ; Zhao, XL; Zhou, CL	1
Brunetti, L; Falini, B; Martelli, MP	1
Kim, KJ; Kim, YD; Lee, YH	1
Houtenbos, I; Ossenkoppele, GJ; Schuurhuis, GJ; van de Loosdrecht, AA; Westers, TM	1
Chang, LJ; Gamble, CL; Izaguirre, CA; Mak, TW; McCulloch, EA; Minden, MD	1
Bloch, A; Craig, RW; Frankfurt, OS; Sakagami, H; Takeda, K	1
AbdAllah, NA; Fisch, H; Flick, DA; Gifford, GE	1
Ajmar, F; Barresi, R; Bianchi Scarrà, G; Garrè, C; Ravazzolo, R; Sessarego, M	1
Fujita, Y; Honma, Y; Hozumi, M; Kasukabe, T; Nomura, H; Sakurai, M; Sampi, K; Tsushima, S	1
Himori, T; Ohnuma, T; Wakui, A	1
Kildahl-Andersen, O; Nissen-Meyer, J	1
Abe, E; Konno, K; Kuribayashi, T; Miyaura, C; Nishii, Y; Suda, T; Tanaka, H	1
Bajorin, DF; Bosl, GJ; Motzer, RJ; Murphy, B; Rodriguez, E	1
Bloch, A	1
Herwig, S; Ma, Y; Su, Q; Tempst, P; Zhang, W	1
Aplan, PD; Chervinsky, DS; Stanulla, M; Wang, J	1
Hirokawa, M; Kitabayashi, A; Miura, AB; Mori, S; Moriyama, M; Onizuka, T; Yamochi, T	1
Ahrens, S; Dunst, J; Harms, D; Jürgens, H; Paulussen, M; Rübe, C; Winkelmann, W; Zoubek, A	1
Pallis, M; Russell, NH; Syan, J	1
Abe, T; Aizawa, Y; Fuse, I; Hashimoto, S; Itoh, H; Koike, T; Shibazaki, Y; Takahashi, H; Takahashi, M; Toba, K; Watanabe, K; Yano, T	1
Pallis, M; Russell, N	1
Appelbaum, FR; Banker, DE; Garrido, SM; Willman, C	1
Bocaccino, CA; Greenberger, JS; Moloney, WC; Szot, SJ	1
Frengley, PA; Lichtman, MA; Peck, WA	2
Fekete, B; Hadházy, G; Szabó, B; Szabó, G	1
Hayashi, M; Honma, Y; Hozumi, M; Okabe, J	1
Sieber, SM	1
Davies, JE; Khurshid, M; Whittaker, JA	1
Bernengo, MG; Pegoraro, L	1
Cadossi, R; Ferrari, S; Montagnani, G; Narni, F; Torelli, G; Torelli, U	1
Augustinos, P; Baer, MR; Kinniburgh, AJ	1
Holte, H; Lie, SO; Smeland, EB; Steen, HB; Stokke, T	1
Durham, J; Fontana, J; Munoz, M	1
Confer, DL; Schubach, WH; Slungaard, A	1
Hozumi, M	1
Bauters, F; Fenaux, P; Jouet, JP; Lai, JL; Lepelley, P	1
Lin, J; Sartorelli, AC	1
Bertani, A; Colotta, F; Mantovani, A; Polentarutti, N; Rambaldi, A; Sica, A	1
Brajtburg, J; Medoff, G; Vertut-Croquin, A	1
Honma, Y; Hozumi, M; Kasukabe, T; Nishii, Y; Suda, T	1
Ciomei, M; Giuliani, FC; Pastori, W	1
Carter, SP; Darzynkiewicz, Z; Old, LJ	1
Arlin, Z; Chiao, JW; Choi, YS; Heil, M; Leung, K; Lutton, JD	1
Bagby, GC; Gowda, SD; Koler, RD	1
Hirji, K; Koeffler, HP; Prokocimer, M; Yelton, L	1
Berrebi, A; Lotem, J; Sachs, L	1
Honma, Y; Hozumi, M; Sakurai, M; Sampi, K	1
Fibach, E; Korenberg, A; Rachmilewitz, EA; Treves, A	1
Brachet, J; Hulin, N; Masera, P; Pileri, A	1
Aye, MT; Mak, TW; McCulloch, EA; Messner, H; Sheinin, R; Till, JE	1
Danieli, G	1
Bolognesi, DP; Green, RW; Metzgar, RS; Miller, DS; Mohanakumar, T	1
Garbarino, G; Hulin, N; Masera, P; Pileri, A	1
Beard, JW; Bonar, RA; Langlois, AJ; Rao, PR; Zischka, R	1
Beard, JW; Heine, U; Langlois, AJ	1
Zubrod, CG	1
Gergely, L; Hadházy, G; Szegedi, G; Tóth, FD	1
Berebbi, M; Carcassonne, Y; Foa, C; Meyer, G	1
Hustinx, TW; Rutten, FJ; Scheres, JM; Wagener, DJ	1
De Pasquale, A; Emilia, G; Ferreira, E; Mauri, C; Quaglino, D	1
Maugel, TK; McFeely, AE; Schumacher, HR	1
Chan, BW	2
Emilia, G; Grossi, G; Quaglino, D; Sauli, S	1
Bernardelli, R; Brusa, L; Gavosto, F; Pileri, A; Tarocco, RP	2
Horiike, S; Iwai, T; Kaneko, H; Kashima, K; Misawa, S; Nakazawa, N; Ohgawara, Y; Sasai, Y; Tamura, A; Taniwaki, M; Tsuda, S; Ueda, Y; Yokota, S	1

Reviews

3 review(s) available for dactinomycin and Acute Myelogenous Leukemia

Article	Year
Current status and future perspectives in targeted therapy of NPM1-mutated AML. Leukemia, 2022, Volume: 36, Issue:10 Topics: Adult; Dactinomycin; Histones; Humans; Leukemia, Myeloid, Acute; Mutation; Nuclear Proteins; Nucleophosmin; Proto-Oncogene Proteins c-bcl-2; Receptors, Antigen, T-Cell; RNA	2022
The action of antitumor agents: a double-edged sword? Medical and pediatric oncology, 1977, Volume: 3, Issue:2 Topics: Alkylating Agents; Animals; Antineoplastic Agents; Azathioprine; Burkitt Lymphoma; Choriocarcinoma; Cyclophosphamide; Dactinomycin; Female; Hodgkin Disease; Humans; Immunosuppressive Agents; Kidney Neoplasms; Leukemia, Myeloid, Acute; Lymphoma; Mechlorethamine; Melphalan; Mercaptopurine; Methotrexate; Mice; Multiple Myeloma; Neoplasms; Prednisone; Pregnancy; Procarbazine; Time Factors; Vincristine	1977
[Induction of the differentiation of tumor cells as an approach to tumor therapy]. Gan to kagaku ryoho. Cancer & chemotherapy, 1987, Volume: 14, Issue:5 Pt 2 Topics: Animals; Antineoplastic Agents; Cell Differentiation; Dactinomycin; Etretinate; Humans; Interferons; Interleukin-3; Leukemia, Experimental; Leukemia, Myeloid, Acute; Neoplasms	1987

Trials

3 trial(s) available for dactinomycin and Acute Myelogenous Leukemia

Article	Year
Dactinomycin induces complete remission associated with nucleolar stress response in relapsed/refractory NPM1-mutated AML. Leukemia, 2021, Volume: 35, Issue:9 Topics: Aged; Antibiotics, Antineoplastic; Cell Nucleolus; Dactinomycin; Drug Resistance, Neoplasm; Female; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Neoplasm Recurrence, Local; Nuclear Proteins; Nucleophosmin; Pilot Projects; Prognosis; Remission Induction; Salvage Therapy	2021
[Prospective multicentre study of chemotherapeutic regimen containing pirarubicin on the treatment of relapsed or refractory acute myeloid leukemia in adults]. Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2014, Volume: 35, Issue:5 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Dactinomycin; Doxorubicin; Etoposide; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Methotrexate; Prospective Studies; Recurrence; Remission Induction	2014
[Clinical evaluation of cefozopran for infections associated with hematological malignancies]. The Japanese journal of antibiotics, 1998, Volume: 51, Issue:8 Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Anemia, Aplastic; Bacterial Infections; Bronchitis; Cefozopran; Cephalosporins; Female; Granulocytes; Hodgkin Disease; Humans; Leukemia; Leukemia, Myeloid, Acute; Leukemia, T-Cell; Leukocyte Count; Lymphoma; Male; Middle Aged; Multiple Myeloma; Peritonitis; Pneumonia; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Sepsis; Severity of Illness Index	1998

Other Studies

70 other study(ies) available for dactinomycin and Acute Myelogenous Leukemia

Article	Year
Dactinomycin in acute myeloid leukemia with NPM1 mutations. European journal of haematology, 2020, Volume: 105, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Biomarkers, Tumor; Dactinomycin; Drug Resistance, Neoplasm; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Nuclear Proteins; Nucleophosmin; Prognosis; Recurrence; Remission Induction; Retreatment; Retrospective Studies; Treatment Outcome; Young Adult	2020
Actinomycin D Targets NPM1c-Primed Mitochondria to Restore PML-Driven Senescence in AML Therapy. Cancer discovery, 2021, 12-01, Volume: 11, Issue:12 Topics: Dactinomycin; Humans; Leukemia, Myeloid, Acute; Mitochondria; Nuclear Proteins; Nucleophosmin	2021
Successful venetoclax and Actinomycin D-based treatment for relapsed acute myeloid leukemia post allogeneic hematopoietic cell transplantation. Bone marrow transplantation, 2021, Volume: 56, Issue:11 Topics: Bridged Bicyclo Compounds, Heterocyclic; Dactinomycin; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Sulfonamides	2021
Venetoclax in combination with low dose Cytarabine and Actinomycin D for primary refractory acute myeloid leukemia patients failing intensive chemotherapy. Leukemia research, 2021, Volume: 111 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bridged Bicyclo Compounds, Heterocyclic; Cytarabine; Dactinomycin; Female; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Retrospective Studies; Salvage Therapy; Sulfonamides; Survival Rate	2021
After the treated mole. Blood, 2014, May-01, Volume: 123, Issue:18 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cyclophosphamide; Dactinomycin; Etoposide; Female; Humans; Hydatidiform Mole; Immunophenotyping; Leukemia, Myeloid, Acute; Methotrexate; Neoplasms, Second Primary; Pregnancy; Trophoblasts; Vincristine	2014
[Efficacy Analysis of MAC Regimen as Salvage Treatment Protocol for Acute Myeloid Leukemia Patients Older Than 55 Years]. Zhongguo shi yan xue ye xue za zhi, 2015, Volume: 23, Issue:2 Topics: Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cytarabine; Dactinomycin; Humans; Leukemia, Myeloid, Acute; Methotrexate; Middle Aged; Recurrence; Remission Induction; Salvage Therapy	2015
Dactinomycin in NPM1-Mutated Acute Myeloid Leukemia. The New England journal of medicine, 2015, Sep-17, Volume: 373, Issue:12 Topics: Antibiotics, Antineoplastic; Bone Marrow; Bone Marrow Examination; Dactinomycin; Humans; Leukemia, Myeloid, Acute; Middle Aged; Mutation; Nuclear Proteins; Nucleophosmin	2015
Secondary leukemia in a child conceived using in vitro fertilization. Pediatrics international : official journal of the Japan Pediatric Society, 2008, Volume: 50, Issue:6 Topics: Antineoplastic Combined Chemotherapy Protocols; Cerebellar Neoplasms; Chemotherapy, Adjuvant; Child, Preschool; Cyclophosphamide; Dactinomycin; Etoposide; Fertilization in Vitro; Humans; Ifosfamide; Leukemia, Myeloid, Acute; Male; Neoplasms, Second Primary; Radiotherapy, Adjuvant; Rhabdomyosarcoma; Vincristine	2008
Quantification of T-cell-mediated apoptosis in heterogeneous leukemia populations using four-color multiparameter flow cytometry. Cytometry. Part A : the journal of the International Society for Analytical Cytology, 2005, Volume: 66, Issue:1 Topics: Apoptosis; Biomarkers, Tumor; CD28 Antigens; Cell Death; Cytotoxicity Tests, Immunologic; Cytotoxicity, Immunologic; Dactinomycin; Flow Cytometry; Fluorescent Dyes; HL-60 Cells; Humans; K562 Cells; Leukemia, Myeloid, Acute; T-Lymphocytes; U937 Cells	2005
Detection of genes coding for human differentiation markers by their transient expression after DNA transfer. Proceedings of the National Academy of Sciences of the United States of America, 1982, Volume: 79, Issue:1 Topics: Animals; Antibodies, Monoclonal; Cell Differentiation; Cells, Cultured; Cycloheximide; Dactinomycin; DNA Restriction Enzymes; DNA, Neoplasm; Fluorescent Antibody Technique; Kinetics; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Mice; Protein Biosynthesis; Transcription, Genetic; Transfection	1982
Macromolecular and cell cycle effects of different classes of agents inducing the maturation of human myeloblastic leukemia (ML-1) cells. Cancer research, 1984, Volume: 44, Issue:6 Topics: Cell Cycle; Cell Differentiation; Cell Line; Cycloheximide; Cytarabine; Dactinomycin; Daunorubicin; DNA Replication; Humans; Kinetics; Leucine; Leukemia, Myeloid, Acute; Protein Biosynthesis; Thymidine; Transcription, Genetic; Tretinoin; Tritium; Uridine	1984
Production of a cytotoxin from phorbol myristate acetate-treated human promyelocytes. Journal of the National Cancer Institute, 1984, Volume: 73, Issue:1 Topics: Animals; Cell Line; Cytotoxins; Dactinomycin; Embryo, Mammalian; Fibroblasts; HeLa Cells; Humans; Kinetics; L Cells; Leukemia, Myeloid, Acute; Mice; Phorbols; Skin; Skin Physiological Phenomena; Tetradecanoylphorbol Acetate	1984
Regulation of acetylcholinesterase expression in the K-562 cell line. Cancer research, 1984, Volume: 44, Issue:9 Topics: Acetylcholinesterase; Butyrates; Butyric Acid; Cell Division; Cell Line; Cycloheximide; Dactinomycin; Enzyme Induction; Humans; Kinetics; Leukemia, Myeloid, Acute	1984
Differentiation in vitro of human myelogenous leukemia cells from patients in relapse. Gan, 1984, Volume: 75, Issue:6 Topics: Adolescent; Adult; Aged; Cell Differentiation; Cells, Cultured; Dactinomycin; Female; Humans; Leukemia, Myeloid, Acute; Lysophospholipids; Male; Middle Aged; Phospholipids	1984
[Differential cell growth inhibition and terminal differentiation induction by chemotherapeutic agents of a human acute myelogenous leukemia cell line (HL-60) in vitro]. Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:8 Topics: Anthraquinones; Antineoplastic Agents; Cell Differentiation; Cell Division; Cell Line; Cell Survival; Cytarabine; Dactinomycin; Daunorubicin; Doxorubicin; Humans; Leukemia, Myeloid, Acute; Mitoxantrone; Phagocytes; Thioguanine; Vincristine	1984
Effect of lymphokines on the production of cytostatic protein factors from human monocytes. Cellular immunology, 1984, Volume: 89, Issue:2 Topics: Adult; Cell Division; Cell Line; Cells, Cultured; Cycloheximide; Cytotoxicity, Immunologic; Dactinomycin; Humans; Kinetics; Leukemia, Myeloid, Acute; Lipopolysaccharides; Lymphocytes; Lymphokines; Monocytes; Protein Biosynthesis; Proteins	1984
1 alpha,25-Dihydroxyvitamin D3 induces differentiation of human myeloid leukemia cells. Biochemical and biophysical research communications, 1981, Oct-15, Volume: 102, Issue:3 Topics: Calcitriol; Cell Differentiation; Cell Line; Dactinomycin; Dimethyl Sulfoxide; Humans; Kinetics; Leukemia, Myeloid, Acute; Tetradecanoylphorbol Acetate	1981
Acute nonlymphocytic leukemia in germ cell tumor patients treated with etoposide-containing chemotherapy. Journal of the National Cancer Institute, 1993, Jan-06, Volume: 85, Issue:1 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carboplatin; Cisplatin; Cyclophosphamide; Dactinomycin; Etoposide; Humans; Leukemia, Myeloid, Acute; Male; Mediastinal Neoplasms; Neoplasms, Germ Cell and Embryonal; Neoplasms, Second Primary; Remission Induction; Salvage Therapy; Testicular Neoplasms; Vinblastine	1993
Dynamics of interaction between DNA-specific antitumor agents and serum-contained cytokines in the initiation of ML-1 human myeloblastic leukemia cell differentiation. Leukemia, 1993, Volume: 7, Issue:8 Topics: Animals; Antineoplastic Agents; Cattle; Cell Differentiation; Cytarabine; Cytokines; Dactinomycin; Daunorubicin; DNA, Neoplasm; Drug Synergism; Humans; Leukemia, Myeloid, Acute; Monocytes; Transforming Growth Factor beta; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha	1993
Distinct temporal patterns of defensin mRNA regulation during drug-induced differentiation of human myeloid leukemia cells. Blood, 1996, Jan-01, Volume: 87, Issue:1 Topics: Acetamides; Biomarkers; Blood Proteins; Cell Differentiation; Cycloheximide; Cytokines; Dactinomycin; Defensins; Dimethyl Sulfoxide; Dimethylformamide; DNA, Complementary; Enzyme Inhibitors; Gene Expression Regulation, Leukemic; Genistein; Granulocyte Colony-Stimulating Factor; Granulocytes; HL-60 Cells; Humans; Interferon-gamma; Isoflavones; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Lymphocytes; Lymphoma, Large B-Cell, Diffuse; Neoplasm Proteins; Recombinant Proteins; RNA Processing, Post-Transcriptional; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Transcription, Genetic; Tretinoin; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha	1996
Topoisomerase II inhibitors induce DNA double-strand breaks at a specific site within the AML1 locus. Leukemia, 1997, Volume: 11, Issue:4 Topics: Amsacrine; Antineoplastic Agents; Base Sequence; Cell Line; Dactinomycin; DNA Damage; DNA, Neoplasm; Doxorubicin; Etoposide; Genes, abl; Humans; Leukemia, Myeloid, Acute; Molecular Sequence Data; Monocytes; Restriction Mapping; Topoisomerase II Inhibitors; Translocation, Genetic	1997
Regulation of BCL-6 gene expression in human myeloid/monocytoid leukemic cells. Leukemia, 1997, Volume: 11, Issue:5 Topics: Adult; Cell Differentiation; Cell Nucleus; Cycloheximide; Dactinomycin; DNA-Binding Proteins; Flow Cytometry; Gene Expression Regulation, Neoplastic; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-6; Tetradecanoylphorbol Acetate; Transcription Factors; Transcription, Genetic; Tumor Cells, Cultured	1997
Second malignancies after treatment for Ewing's sarcoma: a report of the CESS-studies. International journal of radiation oncology, biology, physics, 1998, Sep-01, Volume: 42, Issue:2 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Doxorubicin; Humans; Ifosfamide; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Neoplasms, Second Primary; Radiotherapy Dosage; Sarcoma; Sarcoma, Ewing; Time Factors; Vincristine	1998
Flow cytometric chemosensitivity analysis of blasts from patients with acute myeloblastic leukemia and myelodysplastic syndromes: the use of 7AAD with antibodies to CD45 or CD34. Cytometry, 1999, Dec-01, Volume: 37, Issue:4 Topics: Antibodies; Antigens, CD34; Cell Count; Cytarabine; Dactinomycin; Flow Cytometry; Fluorescent Dyes; Humans; Leukemia, Myeloid, Acute; Leukocyte Common Antigens; Light; Myelodysplastic Syndromes; Scattering, Radiation; Sensitivity and Specificity; Stem Cells; Tumor Cells, Cultured	1999
Cell kinetic study of normal human bone marrow hematopoiesis and acute leukemia using 7AAD/PY. European journal of haematology, 2000, Volume: 64, Issue:1 Topics: Adult; Antigens, CD; Antigens, CD34; Bone Marrow Cells; Burkitt Lymphoma; Cell Cycle; Cells, Cultured; Dactinomycin; DNA; Hematopoiesis; Hematopoietic Stem Cells; Humans; Immunophenotyping; Kinetics; Leukemia; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Myeloid, Acute; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; RNA	2000
P-glycoprotein plays a drug-efflux-independent role in augmenting cell survival in acute myeloblastic leukemia and is associated with modulation of a sphingomyelin-ceramide apoptotic pathway. Blood, 2000, May-01, Volume: 95, Issue:9 Topics: Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blast Crisis; Cell Survival; Ceramides; Cyclosporins; Dactinomycin; Flow Cytometry; Fluorescent Dyes; Genes, MDR; Growth Substances; Humans; Kinetics; Leukemia, Myeloid, Acute; Signal Transduction; Sphingomyelins; Tumor Cells, Cultured; U937 Cells	2000
Three-color versus four-color multiparameter cell cycle analyses of primary acute myeloid leukemia samples. Cytometry, 2000, Apr-15, Volume: 42, Issue:2 Topics: Antibodies; Antigens, CD34; Antineoplastic Agents; Apoptosis; Color; Dactinomycin; Drug Resistance, Neoplasm; Flow Cytometry; Fluorescein-5-isothiocyanate; Fluorescent Dyes; G1 Phase; Humans; Immunophenotyping; K562 Cells; Leukemia, Myeloid, Acute; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins c-bcl-2; S Phase	2000
Chemotherapeutic remissions in Wistar Furth rat acute myelogenous leukemia: a model for human AML. Acta haematologica, 1977, Volume: 57, Issue:4 Topics: Animals; Antineoplastic Agents; Busulfan; Cyclophosphamide; Cytarabine; Dactinomycin; Daunorubicin; Dexamethasone; Disease Models, Animal; Doxorubicin; Leukemia, Experimental; Leukemia, Myeloid, Acute; Methotrexate; Rats; Remission, Spontaneous; Vinblastine; Vincristine	1977
Adaptive enhancement of amino acid transport in human leukemia leukocytes: studies with alpha-aminoisobutyric acid. The Journal of laboratory and clinical medicine, 1975, Volume: 86, Issue:6 Topics: Acute Disease; Adenosine Triphosphate; Aminoisobutyric Acids; Cell Membrane; Cyclic AMP; Cycloheximide; Dactinomycin; Extracellular Space; Humans; Intracellular Fluid; Kinetics; Leucine; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukocytes; Proteins; Time Factors	1975
Interferon production by human leukaemic leucocytes. Acta microbiologica Academiae Scientiarum Hungaricae, 1976, Volume: 23, Issue:1 Topics: Adult; Aged; Cells, Cultured; Child; Child, Preschool; Cycloheximide; Dactinomycin; Humans; Immunosuppressive Agents; Interferons; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Middle Aged; Parainfluenza Virus 1, Human; Puromycin	1976
Actinomycin D restores in vivo sensitivity to differentiation induction of non-differentiating mouse myeloid leukemia cells. International journal of cancer, 1979, Jul-15, Volume: 24, Issue:1 Topics: Animals; Cell Differentiation; Cell Line; Cells, Cultured; Clone Cells; Dactinomycin; Female; Granulocytes; Immunization; Leukemia, Experimental; Leukemia, Myeloid, Acute; Macrophages; Male; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Phagocytosis; Transplantation, Isogeneic	1979
The effect of cytotoxic drugs on neutrophil phagocytosis in vitro and in patients with acute myelogenous leukaemia. British journal of haematology, 1976, Volume: 32, Issue:1 Topics: Antineoplastic Agents; Candida albicans; Cell Survival; Cyclophosphamide; Cytarabine; Dactinomycin; Daunorubicin; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Leukemia, Myeloid, Acute; Methotrexate; Neutrophils; Phagocytosis	1976
Deoxycytidylate deaminase activity and its template stability in human acute lymphoblastic and myeloblastic leukaemic cells. European journal of cancer, 1976, Volume: 12, Issue:8 Topics: Adult; Aged; Child; Child, Preschool; Dactinomycin; DCMP Deaminase; Enzyme Activation; Female; Histocytochemistry; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukocytes; Lymphocyte Activation; Male; Middle Aged; Nucleotide Deaminases; RNA; Templates, Genetic	1976
Accumulation of giant heterogeneous RNA molecules in acute myeloid leukemia blast cells. Cancer research, 1976, Volume: 36, Issue:12 Topics: Dactinomycin; Humans; Kinetics; Leukemia, Myeloid, Acute; Lymphocyte Activation; Lymphocytes; Molecular Weight; Poly A; RNA, Neoplasm; RNA, Ribosomal	1976
Defective c-myc and c-myb RNA turnover in acute myeloid leukemia cells. Blood, 1992, Mar-01, Volume: 79, Issue:5 Topics: Adult; Aged; Blotting, Northern; Dactinomycin; Female; Gene Expression Regulation, Neoplastic; Genes, fos; Genes, myc; Granulocyte-Macrophage Colony-Stimulating Factor; Half-Life; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-myb; RNA; Transcription, Genetic	1992
Differential chromatin structure-dependent binding of 7-aminoactinomycin D in normal and malignant bone marrow hematopoietic cells. Cancer research, 1992, Sep-15, Volume: 52, Issue:18 Topics: Antigens, CD; Cell Cycle; Child; Chromatin; Dactinomycin; DNA; Flow Cytometry; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Survival Analysis; Transcription, Genetic	1992
Potentiation between intracellular cyclic-AMP-elevating agents and inducers of leukemic cell differentiation. Leukemia research, 1985, Volume: 9, Issue:9 Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Cell Differentiation; Cell Line; Cholera Toxin; Cyclic AMP; Dactinomycin; Dimethylformamide; Drug Synergism; Humans; Hypoxanthine; Hypoxanthines; Leukemia, Myeloid, Acute; Time Factors; Tretinoin	1985
Rapid transcriptional down-regulation of c-myc expression during cyclic adenosine monophosphate-promoted differentiation of leukemic cells. The Journal of clinical investigation, 1987, Volume: 79, Issue:5 Topics: 1-Methyl-3-isobutylxanthine; Bucladesine; Cell Differentiation; Cell Line; Cholera Toxin; Cyclic AMP; Dactinomycin; Deoxyribonuclease I; Gene Expression Regulation; Humans; Leukemia, Myeloid, Acute; Oncogenes; RNA; Transcription, Genetic	1987
Translocation t(9;11)(p21;q23) with acute myelomonocytic leukemia after chemotherapy for osteosarcoma: good response to antileukemic drugs. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1987, Volume: 5, Issue:8 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 9; Cyclophosphamide; Dactinomycin; Doxorubicin; Female; Humans; Leukemia, Myeloid, Acute; Methotrexate; Neoplasms, Multiple Primary; Osteosarcoma; Translocation, Genetic	1987
Stimulation by interferon of the differentiation of human promyelocytic leukemia (HL-60) cells produced by retinoic acid and actinomycin D. Journal of interferon research, 1987, Volume: 7, Issue:4 Topics: Aclarubicin; Cell Differentiation; Cell Division; Cell Line; Dactinomycin; Drug Synergism; Humans; Interferons; Leukemia, Myeloid, Acute; Naphthacenes; Tretinoin	1987
Expression of c-jun protooncogene in human myelomonocytic cells. Blood, 1989, Volume: 74, Issue:5 Topics: Cells, Cultured; Cycloheximide; Dactinomycin; DNA-Binding Proteins; Gene Expression; Humans; Leukemia, Myeloid, Acute; Lipopolysaccharides; Monocytes; Neutrophils; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-jun; Proto-Oncogenes; Recombinant Proteins; Reference Values; RNA; RNA, Messenger; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Transcription Factors; Tumor Necrosis Factor-alpha	1989
Two mechanisms of synergism when amphotericin B is used in combination with actinomycin D or 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea against the human promyelocytic leukemia cell line HL-60. Cancer research, 1986, Volume: 46, Issue:12 Pt 1 Topics: Amphotericin B; Antineoplastic Combined Chemotherapy Protocols; Cell Count; Cell Line; Dactinomycin; Drug Synergism; Humans; L-Lactate Dehydrogenase; Leukemia, Myeloid, Acute; Lomustine; Malondialdehyde; Oxidation-Reduction; Potassium; Thymidine	1986
Control of proliferating potential of myeloid leukemia cells during long-term treatment with vitamin D3 analogues and other differentiation inducers in combination with antileukemic drugs: in vitro and in vivo studies. Cancer research, 1987, Jan-15, Volume: 47, Issue:2 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Calcitriol; Cell Differentiation; Cell Division; Cytarabine; Dactinomycin; Daunorubicin; Dexamethasone; Hydroxycholecalciferols; Leukemia, Experimental; Leukemia, Myeloid, Acute; Mice; Time Factors	1987
The influence of amphotericin B on differentiation induced by dimethylsulfoxide and actinomycin D in HL60 and Friend cell lines. Tumori, 1986, Dec-31, Volume: 72, Issue:6 Topics: Amphotericin B; Cell Differentiation; Cell Division; Cell Line; Dactinomycin; Dimethyl Sulfoxide; Drug Synergism; Friend murine leukemia virus; Humans; Kinetics; Leukemia, Erythroblastic, Acute; Leukemia, Myeloid, Acute	1986
Effect of recombinant tumor necrosis factor on HL-60 cells: cell-cycle specificity and synergism with actinomycin D. Journal of cellular physiology, 1987, Volume: 130, Issue:3 Topics: Cell Cycle; Cell Division; Cell Line; Cell Survival; Dactinomycin; Drug Synergism; Glycoproteins; Humans; Kinetics; Leukemia, Myeloid, Acute; Recombinant Proteins; Tumor Necrosis Factor-alpha	1987
Suppression of lymphocyte activation and functions by a leukemia cell-derived inhibitor. Proceedings of the National Academy of Sciences of the United States of America, 1986, Volume: 83, Issue:10 Topics: Cell Differentiation; Cell Line; Dactinomycin; Humans; Immune Tolerance; Interleukin-2; Leukemia, Myeloid, Acute; Lymphocyte Activation; Lymphokines	1986
Regulation of C-myc expression during growth and differentiation of normal and leukemic human myeloid progenitor cells. The Journal of clinical investigation, 1986, Volume: 77, Issue:1 Topics: Bone Marrow Cells; Cell Differentiation; Cell Division; Cell Line; Culture Media; Dactinomycin; Growth Substances; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid, Acute; Nucleic Acid Hybridization; Pregnancy Proteins; Proto-Oncogene Mas; Proto-Oncogene Proteins	1986
Study of differentiation of fresh myelogenous leukemic cells by compounds that induce a human promyelocytic leukemic line (HL-60) to differentiate. Leukemia research, 1985, Volume: 9, Issue:1 Topics: Adult; Aged; Cell Differentiation; Cell Line; Dactinomycin; Dimethyl Sulfoxide; Humans; Hypoxanthine; Hypoxanthines; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Middle Aged; Nitroblue Tetrazolium; Phagocytosis; Thioguanine	1985
Screening for induction of differentiation and toxicity to blast cells by chemotherapeutic compounds in human myeloid leukemia. Leukemia research, 1985, Volume: 9, Issue:2 Topics: Antineoplastic Agents; Bone Marrow; Cell Differentiation; Cells, Cultured; Dactinomycin; Drug Evaluation, Preclinical; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Time Factors	1985
Discrepancy between in-vitro and in-vivo inductions of differentiation by retinoids of human acute promyelocytic leukemia cells in relapse. Leukemia research, 1985, Volume: 9, Issue:12 Topics: Cell Differentiation; Dactinomycin; Humans; In Vitro Techniques; Leukemia, Myeloid, Acute; Male; Middle Aged; Tretinoin	1985
In vitro generation of procoagulant activity by leukemic promyelocytes in response to cytotoxic drugs. American journal of hematology, 1985, Volume: 20, Issue:3 Topics: Antimetabolites; Antimetabolites, Antineoplastic; Cell Line; Dactinomycin; Disseminated Intravascular Coagulation; Granulocytes; Humans; Leukemia, Myeloid, Acute; Lymphoma, Large B-Cell, Diffuse; Puromycin; Thromboplastin	1985
[The activity of chromatin of normal and leukemic leukocytes]. Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles, 1970, Nov-30, Volume: 271, Issue:22 Topics: Autoradiography; Binding Sites; Cell Nucleus; Chromosomes; Dactinomycin; DNA; Humans; Kinetics; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukocytes; Methotrexate; Staining and Labeling; Tritium	1970
Reverse transcriptase activity: increase in marrow cultures from leukaemic patients in relapse and remission. British journal of cancer, 1974, Volume: 29, Issue:6 Topics: Bone Marrow; Bone Marrow Cells; Cells, Cultured; Dactinomycin; DNA, Neoplasm; Humans; Kinetics; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Remission, Spontaneous; RNA-Directed DNA Polymerase; RNA, Neoplasm; Tritium	1974
[1973 treatment of acute leukemias]. Minerva medica, 1974, Dec-15, Volume: 65, Issue:90 Topics: Chlorambucil; Colchicine; Cyclophosphamide; Cytarabine; Dactinomycin; Daunorubicin; Doxorubicin; Drug Therapy, Combination; Fluorouracil; Humans; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Vinblastine; Vincristine	1974
Human leukemia antigens: partial isolation and characterization. Journal of the National Cancer Institute, 1974, Volume: 52, Issue:5 Topics: Animals; Antigens, Neoplasm; Cell Line; Cell Membrane; Centrifugation; Chromatography, Gel; Cycloheximide; Cytarabine; Cytotoxicity Tests, Immunologic; Dactinomycin; Haplorhini; Histocompatibility Antigens; Humans; Immune Sera; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Lymphocytes; Microscopy, Electron; Neuraminidase; Papain; Potassium Chloride; Pronase; Puromycin; Rabbits; Subcellular Fractions; Temperature; Trypsin	1974
Myeloid cell actinomycin binding in human myeloid leukaemia. Acta haematologica, 1974, Volume: 51, Issue:1 Topics: Autoradiography; Binding Sites; Bone Marrow; Bone Marrow Cells; Chromatin; Dactinomycin; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Methotrexate; Tritium	1974
Effects of actinomycin D on avian myeloblast and BAI strain A virus RNA synthesis in vitro. Cancer research, 1966, Volume: 26, Issue:9 Topics: Avian Leukosis Virus; Bone Marrow; Bone Marrow Cells; Culture Techniques; Dactinomycin; Leukemia, Myeloid, Acute; RNA, Viral	1966
Ultrastructural alterations in avian leukemia myeloblasts exposed to actinomycin D in vitro. Cancer research, 1966, Volume: 26, Issue:9 Topics: Animals; Avian Leukosis Virus; Bone Marrow; Bone Marrow Cells; Culture Techniques; Dactinomycin; Leukemia, Myeloid, Acute; Poultry; RNA, Viral	1966
Acute leukemias and Burkitt's lymphoma. Present status of therapy. Cancer, 1968, Volume: 21, Issue:4 Topics: Antineoplastic Agents; Asparaginase; Burkitt Lymphoma; Choriocarcinoma; Cyclophosphamide; Cytarabine; Dactinomycin; Daunorubicin; Female; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Melphalan; Mercaptopurine; Methotrexate; Prednisone; Pregnancy; Vincristine; Wilms Tumor	1968
Comparative study on the interferon production by the leukocytes of healthy and leukaemic subjects. Acta microbiologica Academiae Scientiarum Hungaricae, 1967, Volume: 14, Issue:4 Topics: Amnion; Culture Techniques; Dactinomycin; Humans; Interferons; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Newcastle disease virus; Parainfluenza Virus 1, Human; RNA, Neoplasm; Viral Interference	1967
[Characterization of a hybrid cell line, "human leukemia-Chinese hamster"]. Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles, 1973, Nov-12, Volume: 277, Issue:19 Topics: Animals; Azaguanine; Cell Line; Cricetinae; Dactinomycin; Fibroblasts; Fluorescent Antibody Technique; Genotype; Humans; Hybrid Cells; Karyotyping; Leukemia, Myeloid, Acute; Mitosis; Parainfluenza Virus 1, Human; Selection, Genetic	1973
Trisomy-9 in the bone marrow of a patient with acute myelomonoblastic leukaemia. British journal of haematology, 1974, Volume: 26, Issue:3 Topics: Adult; Autopsy; Bone Marrow Cells; Chromosomes, Human, 6-12 and X; Cytarabine; Dactinomycin; Hemorrhage; Histocytochemistry; Humans; Kidney Neoplasms; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Lung Neoplasms; Male; Neoplasm Metastasis; Radiotherapy; Trisomy; Wilms Tumor	1974
Accelerated active transport of alpha aminoisobutyric acid by human leukemic leukocytes in an amino acid deficient environment. Experimental cell research, 1974, Volume: 88, Issue:2 Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Biological Transport, Active; Carbon Radioisotopes; Cells, Cultured; Culture Media; Cycloheximide; Dactinomycin; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukocytes; Lymphocytes; Sucrose; Time Factors	1974
Relationship between RNA metabolism and cell cycle in acute leukaemia. Acta haematologica, 1972, Volume: 47, Issue:6 Topics: Acute Disease; Autoradiography; Bone Marrow; Bone Marrow Cells; Cells, Cultured; Dactinomycin; Humans; Lectins; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lymphocytes; RNA; Tritium; Uridine	1972
The mononucleosis and leukemic cell. II. RNA synthesis. Acta haematologica, 1968, Volume: 40, Issue:1 Topics: Autoradiography; Dactinomycin; Humans; In Vitro Techniques; Infectious Mononucleosis; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; RNA; Tritium; Uridine	1968
Autoradiographic studies of RNA metabolism in human leukaemic blast cells. Acta haematologica, 1971, Volume: 45, Issue:1 Topics: Autoradiography; Bone Marrow; Bone Marrow Cells; Culture Techniques; Dactinomycin; DNA; Humans; Leucine; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; RNA; Tritium; Uridine	1971
RNA and protein synthesis in proliferating and non-proliferating blast cells of human acute leukaemia. Acta haematologica, 1971, Volume: 45, Issue:2 Topics: Autoradiography; Blood Cells; Blood Proteins; Bone Marrow; Bone Marrow Cells; Cell Division; Culture Techniques; Dactinomycin; DNA; Humans; Leucine; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; RNA; Thymidine; Tritium; Uridine	1971
[Cytoautoradiographic research on cells of acute leukemia]. Bollettino della Societa italiana di biologia sperimentale, 1968, Jan-31, Volume: 44, Issue:2 Topics: Autoradiography; Blood Cells; Dactinomycin; DNA; Humans; Leucine; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukemia, Plasma Cell; Proteins; RNA; Thymidine; Uridine	1968
Degradation of RNA and changes in protein metabolism in human acute leukaemia cells treated with actinomycin D. Revue francaise d'etudes cliniques et biologiques, 1967, Volume: 12, Issue:10 Topics: Dactinomycin; Humans; Leucine; Leukemia; Leukemia, Myeloid, Acute; Proteins; RNA; Time Factors; Tritium; Uridine	1967
Changes in protein metabolism in proliferating and non-proliferating human acute leukaemia cells treated with actinomycin-D. Experientia, 1969, Aug-15, Volume: 25, Issue:8 Topics: Blood Proteins; Dactinomycin; Depression, Chemical; Humans; In Vitro Techniques; Leucine; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lymphocytes; RNA; Tritium	1969