dacarbazine and Uveal Neoplasms

dacarbazine has been researched along with Uveal Neoplasms in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (7.41)18.2507
2000's10 (37.04)29.6817
2010's11 (40.74)24.3611
2020's4 (14.81)2.80

Authors

AuthorsStudies
Abdullah, SE; Baurain, JF; Butler, MO; Carvajal, RD; Curti, B; Demidov, L; Dummer, R; Gastaud, L; Goodall, H; Hamid, O; Hassel, JC; Holland, C; Joshua, AM; Kirkwood, JM; Mauch, C; Milhem, M; Nathan, P; Ochsenreither, S; Orloff, M; Piperno-Neumann, S; Piulats, JM; Rutkowski, P; Sacco, JJ; Salama, AKS; Schlaak, M; Shoushtari, AN; Sullivan, RJ; Yushak, M1
Chen, P; Cun, B; Guo, Y; Li, X; Luo, N; Yang, C; Yang, Y1
Chen, H; Fei, X; Huang, Q; Ji, X; Jiang, D; Meng, X; Qin, R; Sun, F; Wang, A; Wang, Z; Xie, X; Zhao, Y1
Barone, C; Blasi, MA; Cassano, A; Dadduzio, V; Pagliara, M; Quirino, M; Rossi, E; Schinzari, G1
Barker, P; Berking, C; Carvajal, RD; Chapman, PB; Chmielowski, B; Clemett, D; Cocquyt, V; Evans, TRJ; Frank, S; Gastaud, L; Ghiorghiu, D; Joshua, AM; Kapiteijn, E; Kilgour, E; Lai, Z; Linette, G; Lovick, S; Mariani, G; Nathan, P; Piperno-Neumann, S; Piulats, JM; Rodrigues, MJ; Schachter, J; Schwartz, GK; Shoushtari, AN; Spratt, S; Wolter, P1
Achberger, S; Aldrich, W; Binkley, E; Rybicki, L; Singh, A; Triozzi, PL1
Abramson, DH; Albertini, MR; Ambrosini, G; Ancell, K; Bluth, M; Carvajal, RD; Chapman, PB; Dickson, MA; Doyle, A; Erinjeri, J; Flynn, PJ; Gajewski, TF; Hedvat, C; Joshua, AM; Kudchadkar, RR; Lao, CD; Lawson, DH; Lewis, K; Linette, GP; Lutzky, J; Marr, B; Milhem, MM; Panageas, KS; Quevedo, JF; Sato, T; Schwartz, GK; Sosman, JA; Wolchok, JD1
Carvajal, RD; Mann, H; Nathan, PD; Schwartz, GK; Smith, I1
Asselain, B; Bidard, FC; Cassoux, N; Decaudin, D; Diallo, A; Etienne-Grimaldi, MC; Mariani, P; Piperno-Neumann, S; Plancher, C; Rodrigues, M; Servois, V1
Bedikian, AY; Hwu, P; Hwu, WJ; Johnson, MM; Kim, K; McIntyre, S; Papadopoulos, N; Warneke, CL1
Aldrich, W; Dombos, C; Triozzi, PL1
Al-Jamal, RT; Eskelin, S; Kivelä, T; Pyrhönen, S1
Asselain, B; Barillot, E; Bessard, MA; Couturier, J; Dahmani, A; Decaudin, D; Desjardins, L; Donnadieu, MH; Gentien, D; Lantz, O; Laurent, C; Mariani, P; Némati, F; Péguillet, I; Piperno-Neumann, S; Plancher, C; Reyes, C; Robert, D; Roman-Roman, S; Sastre-Garau, X; Saule, S1
Dianov, GL; Digweed, M; Eich, M; Kaina, B; Roos, WP1
Cun, B; Fan, X; Ge, S; Jia, R; Song, X; Wang, H; Zhao, X1
Achberger, S; Aldrich, W; Borden, EC; Grane, R; Singh, AD; Triozzi, PL1
Eskelin, S; Hahka-Kemppinen, M; Kivelä, T; Muhonen, T; Nikkanen, V; Pyrhönen, S; Summanen, P; Tarkkanen, A1
Camp, R; Hemming, AW; Lind, DS1
Ake Hofer, P; Andersson, R; Henriksson, R; Riklund-Ahlström, K1
Gore, M; Hahka-Kemppinen, M; Hansson, J; Humblet, Y; Kivelä, T; Kloke, O; Kruit, WH; Kumpulainen, E; Parvinen, LM; Pyrhönen, S; Suciu, S; Vuoristo, MS1
Grange, JD; Kodjikian, L; Rivoire, M1
Baur, A; Berger, TG; Dieckmann, D; Efferth, T; Funk, JO; Schuler, G; Schultz, ES1
Butt, M; Eswar, CV; Gillis, P; Marshall, E; O'Neill, PA1
Berd, D; De Potter, P; Mastrangelo, MJ; Nathan, FE; Sato, T; Shield, JA; Shields, CL1
Albert, DM; Chappell, R; Darjatmoko, SR; Howes, KA; Koop, BA; Lokken, JM; Mangold, G; Steeves, RA; Syed, NA; Wallow, IH; Windle, JJ1

Reviews

1 review(s) available for dacarbazine and Uveal Neoplasms

ArticleYear
Systemic therapy for unresectable metastatic melanoma: impact of biochemotherapy on long-term survival.
    Journal of immunotoxicology, 2008, Volume: 5, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Dacarbazine; Databases, Factual; Disease-Free Survival; Female; Humans; Interferon-alpha; Interleukin-2; Male; Melanoma; Neoplasm Metastasis; Retrospective Studies; Skin Neoplasms; Survival Rate; Uveal Neoplasms; Vinblastine

2008

Trials

11 trial(s) available for dacarbazine and Uveal Neoplasms

ArticleYear
Overall Survival Benefit with Tebentafusp in Metastatic Uveal Melanoma.
    The New England journal of medicine, 2021, 09-23, Volume: 385, Issue:13

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Cytokine Release Syndrome; Dacarbazine; Exanthema; Female; Humans; Ipilimumab; Male; Melanoma; Middle Aged; Recombinant Fusion Proteins; Survival Analysis; Uveal Neoplasms

2021
Cisplatin, dacarbazine and vinblastine as first line chemotherapy for liver metastatic uveal melanoma in the era of immunotherapy: a single institution phase II study.
    Melanoma research, 2017, Volume: 27, Issue:6

    Topics: Cisplatin; Dacarbazine; Disease-Free Survival; Female; Humans; Immunotherapy; Male; Melanoma; Middle Aged; Uveal Neoplasms; Vinblastine

2017
Selumetinib in Combination With Dacarbazine in Patients With Metastatic Uveal Melanoma: A Phase III, Multicenter, Randomized Trial (SUMIT).
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2018, 04-20, Volume: 36, Issue:12

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Dacarbazine; Double-Blind Method; Female; Humans; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Placebos; Progression-Free Survival; Uveal Neoplasms

2018
A prospective trial of adjuvant therapy for high-risk uveal melanoma: assessing 5-year survival outcomes.
    The British journal of ophthalmology, 2020, Volume: 104, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Chemotherapy, Adjuvant; Dacarbazine; Disease-Free Survival; Female; Humans; Infusions, Intravenous; Injections, Subcutaneous; Interferon alpha-2; Interferon-alpha; Male; Melanoma; Middle Aged; Prospective Studies; Survival Rate; Uveal Neoplasms; Young Adult

2020
Effect of selumetinib vs chemotherapy on progression-free survival in uveal melanoma: a randomized clinical trial.
    JAMA, 2014, Jun-18, Volume: 311, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Benzimidazoles; Dacarbazine; Disease Progression; Female; Humans; Male; Melanoma; Middle Aged; Survival Analysis; Temozolomide; Treatment Outcome; Uveal Neoplasms

2014
Study design and rationale for a randomised, placebo-controlled, double-blind study to assess the efficacy of selumetinib (AZD6244; ARRY-142886) in combination with dacarbazine in patients with metastatic uveal melanoma (SUMIT).
    BMC cancer, 2015, Jun-10, Volume: 15

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Dacarbazine; Disease-Free Survival; Female; Humans; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Uveal Neoplasms

2015
The association of blood angioregulatory microRNA levels with circulating endothelial cells and angiogenic proteins in patients receiving dacarbazine and interferon.
    Journal of translational medicine, 2012, Dec-05, Volume: 10

    Topics: Angiogenic Proteins; Cell Movement; Dacarbazine; Endothelial Cells; Humans; Interferon alpha-2; Interferon-alpha; Melanoma; MicroRNAs; Neovascularization, Pathologic; Recombinant Proteins; Uveal Neoplasms

2012
Chemoimmunotherapy with bleomycin, vincristine, lomustine, dacarbazine (BOLD), and human leukocyte interferon for metastatic uveal melanoma.
    Cancer, 2002, Dec-01, Volume: 95, Issue:11

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Dacarbazine; Disease-Free Survival; Female; Humans; Injections, Intravenous; Interferon-alpha; Lomustine; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Treatment Outcome; Uveal Neoplasms; Vincristine

2002
Bleomycin, vincristine, lomustine and dacarbazine (BOLD) in combination with recombinant interferon alpha-2b for metastatic uveal melanoma.
    European journal of cancer (Oxford, England : 1990), 2003, Volume: 39, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Dacarbazine; Disease-Free Survival; Feasibility Studies; Female; Humans; Interferon alpha-2; Interferon-alpha; Lomustine; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Prospective Studies; Recombinant Proteins; Treatment Outcome; Uveal Neoplasms; Vincristine

2003
A prospective single arm phase II study of dacarbazine and treosulfan as first-line therapy in metastatic uveal melanoma.
    Melanoma research, 2006, Volume: 16, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Dacarbazine; Female; Humans; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Prospective Studies; Thrombocytopenia; Uveal Neoplasms

2006
BOLD+interferon in the treatment of metastatic uveal melanoma: first report of active systemic therapy.
    Journal of experimental & clinical cancer research : CR, 1997, Volume: 16, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Dacarbazine; Female; Humans; Interferon alpha-2; Interferon-alpha; Lomustine; Lung Diseases; Male; Melanoma; Middle Aged; Recombinant Proteins; Uveal Neoplasms; Vincristine

1997

Other Studies

15 other study(ies) available for dacarbazine and Uveal Neoplasms

ArticleYear
Ubiquitination and degradation of MGMT by TRIM72 increases the sensitivity of uveal melanoma cells to Dacarbazine treatment.
    Cancer biomarkers : section A of Disease markers, 2022, Volume: 34, Issue:2

    Topics: Adult; Cell Line, Tumor; Dacarbazine; DNA Modification Methylases; DNA Repair Enzymes; Humans; Melanoma; Tripartite Motif Proteins; Tumor Suppressor Proteins; Ubiquitination; Uveal Neoplasms

2022
Proteomics analysis: inhibiting the expression of P62 protein by chloroquine combined with dacarbazine can reduce the malignant progression of uveal melanoma.
    BMC cancer, 2022, Apr-14, Volume: 22, Issue:1

    Topics: Animals; Cell Line, Tumor; Chloroquine; Dacarbazine; Humans; Melanoma; Mice; Mice, Nude; Proteomics; Tumor Microenvironment; Uveal Neoplasms

2022
Selumetinib shows promise in metastatic uveal melanoma.
    Cancer discovery, 2013, Volume: 3, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Clinical Trials, Phase II as Topic; Dacarbazine; Disease-Free Survival; Eye Neoplasms; Humans; Melanoma; Neoplasm Metastasis; Temozolomide; Uveal Neoplasms

2013
Uveal melanoma therapy on the horizon?
    Cancer discovery, 2014, Volume: 4, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Benzimidazoles; Dacarbazine; Female; Humans; Male; Melanoma; Uveal Neoplasms

2014
Phase II Trial of Bevacizumab in Combination With Temozolomide as First-Line Treatment in Patients With Metastatic Uveal Melanoma.
    The oncologist, 2016, Volume: 21, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Dacarbazine; Disease-Free Survival; Drug Administration Schedule; Female; Humans; Male; Melanoma; Middle Aged; Perfusion Imaging; Temozolomide; Tomography, X-Ray Computed; Treatment Outcome; Uveal Neoplasms; Vascular Endothelial Growth Factor A

2016
Differential effects of imatinib mesylate against uveal melanoma in vitro and in vivo.
    Melanoma research, 2008, Volume: 18, Issue:6

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Benzamides; Cell Line, Tumor; Cell Proliferation; Dacarbazine; Humans; Imatinib Mesylate; Melanoma; Mice; Piperazines; Pyrimidines; Temozolomide; Uveal Neoplasms; Xenograft Model Antitumor Assays

2008
Long-term progression-free survival in metastatic uveal melanoma after chemoimmunotherapy and consolidation thermoablation.
    Acta oncologica (Stockholm, Sweden), 2009, Volume: 48, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Catheter Ablation; Combined Modality Therapy; Dacarbazine; Disease-Free Survival; Humans; Immunotherapy; Interferon Type I; Liver Neoplasms; Lomustine; Magnetic Resonance Imaging; Male; Melanoma; Middle Aged; Prognosis; Recombinant Proteins; Treatment Outcome; Uveal Neoplasms; Vincristine

2009
Establishment and characterization of a panel of human uveal melanoma xenografts derived from primary and/or metastatic tumors.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2010, Apr-15, Volume: 16, Issue:8

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Dacarbazine; Female; Gene Expression Profiling; Humans; In Situ Hybridization, Fluorescence; Male; Melanoma; Mice; Mice, SCID; Middle Aged; Neoplasm Metastasis; Nitrosourea Compounds; Oligonucleotide Array Sequence Analysis; Organophosphorus Compounds; Polymorphism, Single Nucleotide; Temozolomide; Tumor Cells, Cultured; Uveal Neoplasms; Xenograft Model Antitumor Assays

2010
Nijmegen breakage syndrome protein (NBN) causes resistance to methylating anticancer drugs such as temozolomide.
    Molecular pharmacology, 2010, Volume: 78, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Caspase 7; Cell Cycle Proteins; Cell Line, Transformed; Cell Line, Tumor; Dacarbazine; DNA Methylation; Drug Resistance, Neoplasm; Fibroblasts; Guanine; Homozygote; Humans; Melanoma; Methylnitronitrosoguanidine; Mutagens; Mutation; Necrosis; Nijmegen Breakage Syndrome; Nuclear Proteins; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Temozolomide; Uveal Neoplasms

2010
Combination of oncolytic adenovirus and dacarbazine attenuates antitumor ability against uveal melanoma cells via cell cycle block.
    Cancer biology & therapy, 2012, Jan-15, Volume: 13, Issue:2

    Topics: Adenoviridae; Antineoplastic Agents, Alkylating; Apoptosis; Cell Cycle; Cell Line, Tumor; Combined Modality Therapy; Cytopathogenic Effect, Viral; Dacarbazine; Drug Synergism; Humans; Melanoma; Oncolytic Virotherapy; Oncolytic Viruses; Time Factors; Uveal Neoplasms; Virus Replication

2012
Combined liver and pancreas resection with biochemotherapy for metastatic ocular melanoma.
    Journal of hepato-biliary-pancreatic surgery, 2002, Volume: 9, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Dacarbazine; Eye Enucleation; Female; Hepatectomy; Humans; Interferon-alpha; Liver Neoplasms; Lymph Node Excision; Lymphatic Metastasis; Melanoma; Middle Aged; Pancreatectomy; Pancreatic Neoplasms; Uveal Neoplasms

2002
Effects of interferon-alpha, verapamil and dacarbazine in the treatment of advanced malignant melanoma.
    Melanoma research, 2003, Volume: 13, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Calcium Channel Blockers; Dacarbazine; Female; Humans; Interferon alpha-2; Interferon-alpha; Male; Maximum Tolerated Dose; Melanoma; Middle Aged; Neoplasm Staging; Radionuclide Imaging; Recombinant Proteins; Remission Induction; Skin Neoplasms; Survival Rate; Treatment Outcome; Uveal Neoplasms; Verapamil

2003
Prolonged survival after resection of liver metastases from uveal melanoma and intra-arterial chemotherapy.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2005, Volume: 243, Issue:6

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Dacarbazine; Fatal Outcome; Female; Follow-Up Studies; Hepatectomy; Humans; Injections, Intra-Arterial; Liver Neoplasms; Melanoma; Neoplasm Metastasis; Nitrosourea Compounds; Organophosphorus Compounds; Survival Rate; Time Factors; Uveal Neoplasms

2005
Artesunate in the treatment of metastatic uveal melanoma--first experiences.
    Oncology reports, 2005, Volume: 14, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Artemisia; Artemisinins; Artesunate; Dacarbazine; Fatal Outcome; Female; Humans; Liver Neoplasms; Lung Neoplasms; Male; Melanoma; Sesquiterpenes; Time Factors; Treatment Outcome; Uveal Neoplasms

2005
Transgenic mice with pigmented intraocular tumors: tissue of origin and treatment.
    Investigative ophthalmology & visual science, 1998, Volume: 39, Issue:13

    Topics: Animals; Antigens, Neoplasm; Antigens, Polyomavirus Transforming; Dacarbazine; Fas Ligand Protein; Female; Immunohistochemistry; In Situ Hybridization; Male; Melanoma; Melanoma-Specific Antigens; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Transgenic; Neoplasm Proteins; Pigment Epithelium of Eye; S100 Proteins; Uveal Neoplasms

1998