dacarbazine has been researched along with Thrombocytopenia in 84 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (15.48) | 18.7374 |
| 1990's | 12 (14.29) | 18.2507 |
| 2000's | 34 (40.48) | 29.6817 |
| 2010's | 24 (28.57) | 24.3611 |
| 2020's | 1 (1.19) | 2.80 |
| Authors | Studies |
|---|---|
| Garzio, K; Grossman, S; Holdhoff, M; McElroy, K; Ozer, B; Yankulina, O | 1 |
| Barbaro, B; Barone, C; Basso, M; Calegari, MA; Camarda, F; Cassano, A; Cenci, T; de Pascalis, I; Gori, S; Inno, A; Larocca, LM; Martini, M; Monterisi, S; Orlandi, A; Santini, D; Tonini, G | 1 |
| Cloughesy, TF; Faiq, N; Green, R; Green, S; Hu, J; Lai, A; Mellinghoff, I; Nghiemphu, PL; Yu, A | 1 |
| Buonerba, C; Cerbone, L; Cordua, N; De Placido, S; Di Lorenzo, G; Lamberti, G; Marinelli, A; Peluso, G | 1 |
| Ahern, C; Ames, MM; Blaney, SM; Fouladi, M; Gilbertson, RJ; Horton, T; Hummel, TR; Ingle, AM; McGovern, RM; Reid, JM; Wagner, L; Weigel, B | 1 |
| Gupta, T; Jalali, R; Mohanty, S; Moiyadi, A | 1 |
| Brennan, M; Garcon, MC; Kaley, K; Rodriguez, G; Rodriguez, T; Saif, MW | 1 |
| Bai, B; Cai, QC; Cai, QQ; Gao, Y; Huang, HQ; Jiang, WQ; Wang, XX; Xia, YF; Xia, ZJ | 1 |
| Claringbold, PG; Kesavan, M; Turner, JH | 1 |
| Cui, XL; Li, HL; Lin, S; Zhang, JN | 1 |
| Chamberlain, MC; Cloughesy, T; Desjardins, A; Glantz, M; Mikkelsen, T; Reardon, DA; Schiff, D; Wen, PY | 1 |
| Fersht, N; Mandeville, HC; Mycroft, J; O'Leary, B; Saran, F; Solda, F; Vaidya, S; Zacharoulis, S | 1 |
| Chi, ZH; Cui, CL; Guo, J; Lian, HY; Si, L; Yuan, XQ | 1 |
| Fujioka, Y; Homori, M; Kurita, H; Miyazaki, H; Nagane, M; Nozue, K; Shimizu, S; Shiokawa, Y; Waha, A | 1 |
| Armstrong, TS; Bondy, M; Cao, Y; Gilbert, MR; Manning, R; Okcu, MF; Scheurer, ME; Vera-Bolaños, E; Zhou, R | 1 |
| Hop, WC; Jeurissen, FJ; Roon, K; Taphoorn, MJ; Vecht, CJ; Zwinkels, H | 1 |
| Abdi, E; Beith, J; Corrie, PG; Kefford, RF; Kotasek, D; Margison, GP; Middleton, MR; Mortimer, P; Palmer, C; Ranson, M; Thomas, NP; Watson, AJ | 1 |
| Hwu, WJ; Patel, SP; Trinh, VA | 1 |
| Casey, DA; Chou, AJ; Merchant, MS; Merola, PR; Meyers, PA; Price, AP; Wexler, LH | 1 |
| Batchelor, TT; Ciampa, A; Doherty, LM; Drappatz, J; Gerard, M; Kesari, S; Lafrankie, DC; Ligon, KL; Muzikansky, A; Norden, AD; Phan, P; Sceppa, C; Schiff, D; Weiss, SE; Wen, PY; Wong, ET; Young, G | 1 |
| Anderson, WS; Dunn, I; Norden, A; Sure, D | 1 |
| Bartels, U; Baruchel, S; Bouffet, E; Eisenstat, D; Gammon, J; Huang, A; Hukin, J; Johnston, DL; Samson, Y; Sharp, JR; Stempak, D; Stephens, D; Tabori, U | 1 |
| Daehler, M; Grutsch, JF; Gupta, D; Hall, JL; Levin, RD; Lis, CG | 1 |
| Elandt, K; Heinzl, H; Marosi, C; Preusser, M; Schwarzinger, I | 1 |
| Boyer, P; Dufour, P; Fischer-Lokou, D; Froelich, S; Gaub, MP; Kehrli, P; Maitrot, D; Noël, G; Schott, R | 1 |
| Burke, W; Califano, R; Carmichael, J; Gore, M; Greystoke, A; Khan, OA; Larkin, J; Lorigan, P; Margison, GP; McGown, G; Middleton, MR; Stone, J; Thorncroft, M; Watson, AJ; Wellman, S | 1 |
| Amin, P; Cheston, S; Dhople, A; DiBiase, S; Flannery, T; Meisenberg, B; Patel, A; Patel, S | 1 |
| Chen, ZP; Jiang, XB; Mu, YG; Sai, K; Shen, D; Yang, QY; Zhang, XH | 1 |
| Arcella, A; Caporello, P; De Sanctis, V; Enrici, RM; Giangaspero, F; Lanzetta, G; Minniti, G; Salvati, M; Scaringi, C | 1 |
| Anderson, P; Bilton, SD; Chang, EL; Fontanilla, HP; Green, HL; Grosshans, DR; Hayes-Jordan, A; Mahajan, A; McAleer, MF; Pinnix, CC; Subbiah, V; Sulman, EP; Woo, SY | 1 |
| Coan, A; Desjardins, A; Friedman, HS; Gururangan, S; Herndon, JE; Janney, D; Lipp, ES; McLendon, R; Peters, KB; Reardon, DA; Rich, JN; Sathornsumetee, S; Vredenburgh, JJ | 1 |
| Blasco, J; Bruna, J; Gil, M; Graus, F; Pineda, E; Simó, M; Velasco, R; Verger, E | 1 |
| Bardier, A; Blot, E; Decaudin, D; Pouillart, P; Veyradier, A; Zagame, OL | 1 |
| Ames, P; Boasberg, PD; Deck, R; Fournier, P; Gammon, G; Kim, H; Kristedja, TS; Martin, M; O'Day, SJ; Piro, L; Shinn, K; Wang, HJ | 1 |
| Nohgawa, M; Sugiyama, T; Yonetani, N | 1 |
| Couanet, D; Doz, F; Dugan, M; Frappaz, D; Griffiths, PD; Hobson, R; Ironside, J; Jaspan, T; Jouvet, A; Lashford, LS; Pearson, AD; Robson, K; Thiesse, P; Vassal, G | 1 |
| Agarwala, SS; Kirkwood, JM | 1 |
| Foster, T; Newlands, ES; Zaknoen, S | 1 |
| Barone, C; Caldarelli, M; Cefalo, G; Garrè, ML; Lazzareschi, I; Madon, E; Maira, G; Massimino, M; Mastrangelo, S; Mazzarella, G; Riccardi, A; Riccardi, R; Ridola, V; Ruggiero, A; Sandri, A | 1 |
| Boxall, J; Marples, M; Meyer, T; Napier, MP; Rustin, GJ; Strauss, SJ | 1 |
| Baker, SD; Batra, VK; Cutler, DL; Donehower, RC; Rudek, MA; Statkevich, P | 1 |
| Basso, U; Brandes, AA; Cavallo, G; Ermani, M; Ferreri, AJ; Monfardini, S; Panucci, MG; Reni, M; Scopece, L; Tosoni, A; Vastola, F | 1 |
| Boddy, AV; Calvert, AH; Curtin, NJ; Harris, AL; Hickson, I; Jones, C; Margison, GP; McGown, G; McHugh, P; Middleton, MR; Newell, DR; Olsen, A; Plummer, ER; Thorncroft, M; Watson, AJ | 1 |
| Di Lauro, V; Freschi, A; La Mura, N; Nigri, P; Scalone, S; Veronesi, A; Zanetti, M | 1 |
| Koch, D; Wick, W | 1 |
| Abate, ME; Attinà, G; Caldarelli, M; Cefalo, G; Clerico, A; Colosimo, C; Di Rocco, C; Garré, ML; Lazzareschi, I; Madon, E; Massimino, M; Maurizi, P; Mazzarella, G; Riccardi, R; Ridola, V; Ruggiero, A; Sandri, A | 1 |
| Abrey, LE; Demopoulos, A; Malkin, MG; Omuro, AM; Raizer, JJ | 1 |
| Butt, M; Eswar, CV; Gillis, P; Marshall, E; O'Neill, PA | 1 |
| Geng, Y; Li, EX; Li, SM; Shang, JT; Shi, F; Wu, YY; Xu, Z; Zhang, YT | 1 |
| Gerber, DE; Grossman, SA; Kleinberg, L; Parisi, MA; Zeltzman, M | 1 |
| Auvrignon, A; Baunin, C; Bergeron, C; Biassoni, L; Brisse, H; Chisholm, J; Coze, C; Defachelles, AS; Dickinson, F; Djafari, L; Giammarile, F; Hobson, R; McHugh, K; Morland, B; Mosseri, V; Munzer, C; Rubie, H; Valteau-Couanet, D; Vassal, G; Weston, C | 1 |
| Bate, SC; Beirne, DA; Eisen, TG; Gibbens, IM; Gore, ME; Hughes, SA; Larkin, JM; Patel, PM; Thomas, K | 1 |
| Bartlett, NL; Canellos, GP; Cheson, BD; Friedberg, JW; Johnson, JL; Johnson, KB; Niedzwiecki, D; van Besien, K; Zelenetz, AD | 1 |
| Gamble, JF; Loh, KK; Rodgers, RW; Shullenberger, CC | 1 |
| Bond, WH; Chenoweth, L; Einhorn, LH; Stevens, EE; Williams, SD | 1 |
| Kennealey, GT; Kirkwood, JM; Luikart, SD | 1 |
| Bramwell, VH; Buesa, J; Mouridsen, HT; Pinedo, HM; Santoro, A; Somers, R; van Oosterom, AT; van Unnik, JA; Vendrik, CP; Wagener, T | 1 |
| Biran, S; Pfeffer, MR; Sulkes, A | 1 |
| Buesa, JM; Estrada, E; Gracia, M; Hidalgo, OF; Lacave, AJ; Valle, M | 1 |
| Douglass, HO; Engstrom, PF; MacIntyre, JM; Mittelman, A; Muggia, F | 1 |
| Avilés, A; Díaz-Maqueo, JC; García, EL; Guzmán, R; Talavera, A | 1 |
| Buesa, J; Casali, P; Mouridsen, H; Rankin, E; Santoro, A; Somers, R; Spooner, D; Steward, W; Tursz, T; Verweij, J | 1 |
| Bleehen, NM; Brampton, M; Calvert, AH; Lee, SM; Newlands, ES; Rustin, GJ; Selby, P; Stevens, MF; Thatcher, N | 1 |
| Angeli, A; Berruti, A; Caraci, P; Dogliotti, L; Orlandi, F; Pivano, G; Puligheddu, B | 1 |
| A'Hern, R; Atkinson, H; Chang, J; Gore, ME; Lorentzos, A | 1 |
| Dolan, ME; Janisch, L; Mitchell, RB; Ratain, MJ; Schilsky, RL; Vogelzang, NJ | 1 |
| Lee, SM; Margison, GP; Thatcher, N; Woodcock, AA | 1 |
| Gustavsson, A | 1 |
| Martín, G | 1 |
| Ascierto, PA; Cellerino, R; Comella, G; Comella, P; Daponte, A; DeLena, M; Gravina, A; Marini, G; Melucci, MT; Palmieri, G | 1 |
| Affrime, MB; Batra, VK; Cutler, DL; Hajian, G; Heft, S; Jen, JF; Pai, SM; Zambas, DN | 1 |
| Gerson, SL; Haaga, J; Liu, L; Majka, S; Spiro, TP; Willson, JK | 1 |
| Affronti, ML; Cokgor, L; Early, M; Edwards, S; Friedman, AH; Friedman, HS; Gururangan, S; Herndon, JE; McLendon, RE; Provenzale, JM; Quinn, JA; Rich, JN; Sampson, JH; Stafford-Fox, V; Tourt-Uhlig, S; Zaknoen, S | 1 |
| Bafaloukos, D; Briassoulis, E; Fountzilas, G; Georgoulias, V; Gogas, H; Kalofonos, Ch; Karabelis, A; Kosmidis, P; Samantas, E; Skarlos, D | 1 |
| Babović, N; Jelić, S; Kreacić, M; Matković, S; Popov, I; Stamatović, L | 1 |
| Baxter, D; Cunningham, TJ; Horton, J; Nelson, L; Olson, KB; Rosenbaum, C; Sponzo, RW; Taylor, SG | 1 |
| Colsky, J; Costanza, ME; Cunningham, T; Nathanson, L; Regelson, W; Schoenfeld, D; Sedransk, N; Wolter, J | 1 |
| Hill, G; Johnson, RO; Krementz, E; Metter, G; Wilson, W | 1 |
| Costanzi, JJ | 1 |
| Avril, MF; Bonneterre, J; Cupissol, D; Fargeot, P; Fumoleau, P; Grob, JJ; Israel, L; Kalis, B; Kerbrat, P; Lambert, D | 1 |
| Binder, M; Dorffner, R; Glebowski, E; Pehamberger, H; Winkler, A; Wolff, K | 1 |
| Richards, JM | 1 |
| Bellet, RE; Berd, D; Mastrangelo, MJ; McClay, EF | 1 |
| Brunet, R; Bui, NB; Chauvergne, J; Coindre, JM; Durand, M; Hocke, C | 1 |
1 review(s) available for dacarbazine and Thrombocytopenia
| Article | Year |
|---|---|
The safety of temozolomide in the treatment of malignancies.
Topics: Antineoplastic Agents, Alkylating; Clinical Trials as Topic; Combined Modality Therapy; Dacarbazine; Humans; Lymphopenia; Nausea; Neoplasms; Neutropenia; Radiotherapy; Temozolomide; Thrombocytopenia; Vomiting | 2009 |
53 trial(s) available for dacarbazine and Thrombocytopenia
| Article | Year |
|---|---|
A phase 2 study of temozolomide in pretreated metastatic colorectal cancer with MGMT promoter methylation.
Topics: Aged; Aged, 80 and over; Anemia; Antineoplastic Agents, Alkylating; Colorectal Neoplasms; Dacarbazine; Disease-Free Survival; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Female; GTP Phosphohydrolases; Humans; Membrane Proteins; Middle Aged; Mutation; Nausea; Neoplasm Metastasis; Promoter Regions, Genetic; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins p21(ras); Retreatment; Survival Rate; Temozolomide; Thrombocytopenia; Treatment Outcome; Tumor Suppressor Proteins; Vomiting | 2017 |
Report of safety of pulse dosing of lapatinib with temozolomide and radiation therapy for newly-diagnosed glioblastoma in a pilot phase II study.
Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Drug Administration Schedule; Female; Glioblastoma; Humans; Karnofsky Performance Status; Lapatinib; Male; Middle Aged; Necrosis; Pilot Projects; Quinazolines; Temozolomide; Thrombocytopenia; Treatment Outcome | 2017 |
High-dose fotemustine in temozolomide-pretreated glioblastoma multiforme patients: A phase I/II trial.
Topics: Administration, Intravenous; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Disease-Free Survival; Drug Administration Schedule; Female; Glioblastoma; Humans; Incidence; Male; Middle Aged; Neoplasm Recurrence, Local; Nitrosourea Compounds; Organophosphorus Compounds; Temozolomide; Thrombocytopenia | 2018 |
A pediatric phase 1 trial of vorinostat and temozolomide in relapsed or refractory primary brain or spinal cord tumors: a Children's Oncology Group phase 1 consortium study.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Child; Child, Preschool; Dacarbazine; DNA Modification Methylases; DNA Repair Enzymes; Dose-Response Relationship, Drug; Female; Histones; Humans; Hydroxamic Acids; Leukocytes, Mononuclear; Male; Maximum Tolerated Dose; Neutropenia; Promoter Regions, Genetic; Recurrence; Spinal Cord Neoplasms; Temozolomide; Thrombocytopenia; Tumor Suppressor Proteins; Vorinostat | 2013 |
Hematological toxicity of combined 177Lu-octreotate radiopeptide chemotherapy of gastroenteropancreatic neuroendocrine tumors in long-term follow-up.
Topics: Adult; Aged; Anemia; Antineoplastic Agents; Blood Platelets; Capecitabine; Dacarbazine; Deoxycytidine; Digestive System Neoplasms; Drug Therapy, Combination; Female; Fluorouracil; Follow-Up Studies; Hematologic Diseases; Humans; Incidence; Intestinal Neoplasms; Male; Middle Aged; Neuroendocrine Tumors; Neutrophils; Octreotide; Pancreatic Neoplasms; Radiopharmaceuticals; Randomized Controlled Trials as Topic; Stomach Neoplasms; Temozolomide; Thrombocytopenia; Treatment Outcome | 2014 |
Chemotherapy alleviates subacute recurrent glioma-associated refractory cerebral edema by downregulating vascular endothelial growth factor.
Topics: Adult; Aged; Brain Edema; Brain Neoplasms; Cisplatin; Dacarbazine; Down-Regulation; Female; Glioma; Humans; Leukopenia; Male; Middle Aged; Nimustine; Postoperative Complications; Temozolomide; Thrombocytopenia; Treatment Outcome; Vascular Endothelial Growth Factor A; Young Adult | 2014 |
Phase 1 dose escalation trial of the safety and pharmacokinetics of cabozantinib concurrent with temozolomide and radiotherapy or temozolomide after radiotherapy in newly diagnosed patients with high-grade gliomas.
Topics: Adult; Aged; Alanine Transaminase; Anilides; Antineoplastic Combined Chemotherapy Protocols; Aspartate Aminotransferases; Astrocytoma; Brain Neoplasms; Chemoradiotherapy; Chemoradiotherapy, Adjuvant; Constipation; Dacarbazine; Diarrhea; Fatigue; Female; Glioblastoma; Humans; Hypertension; L-Lactate Dehydrogenase; Leukopenia; Maintenance Chemotherapy; Male; Maximum Tolerated Dose; Middle Aged; Nausea; Neoplasm Grading; Neurosurgical Procedures; Neutropenia; Pyridines; Temozolomide; Thrombocytopenia; Treatment Outcome | 2016 |
[Hepatic intra-arterial bio-chemotherapy for the treatment of melanoma patients with liver metastasis: a phase II clinical study].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytokine-Induced Killer Cells; Dacarbazine; Disease-Free Survival; Female; Follow-Up Studies; Granulocyte-Macrophage Colony-Stimulating Factor; Hepatic Artery; Humans; Immunotherapy, Adoptive; Infusions, Intra-Arterial; Interleukin-2; Liver Neoplasms; Male; Melanoma; Middle Aged; Nitrosourea Compounds; Organophosphorus Compounds; Recombinant Proteins; Remission Induction; Survival Rate; Thrombocytopenia; Young Adult | 2008 |
A phase I study of extended dosing with lomeguatrib with temozolomide in patients with advanced melanoma.
Topics: Aged; Aged, 80 and over; Anemia; Antineoplastic Agents; Child; Dacarbazine; Dose-Response Relationship, Drug; Female; Humans; Melanoma; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Neutropenia; Patient Selection; Purines; Skin Neoplasms; Temozolomide; Thrombocytopenia | 2009 |
Irinotecan and temozolomide for Ewing sarcoma: the Memorial Sloan-Kettering experience.
Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Camptothecin; Child; Child, Preschool; Colitis; Dacarbazine; Diarrhea; Female; Humans; Irinotecan; Male; Neutropenia; Pneumonia; Recurrence; Remission Induction; Retrospective Studies; Sarcoma, Ewing; Temozolomide; Thrombocytopenia; Young Adult | 2009 |
Phase I study of vandetanib with radiotherapy and temozolomide for newly diagnosed glioblastoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Diverticulitis; Drug Administration Schedule; ErbB Receptors; Female; Gastrointestinal Hemorrhage; Glioblastoma; Humans; Male; Maximum Tolerated Dose; Middle Aged; Neutropenia; Piperidines; Quinazolines; Temozolomide; Thrombocytopenia; Vascular Endothelial Growth Factor Receptor-2 | 2010 |
A multi-centre Canadian pilot study of metronomic temozolomide combined with radiotherapy for newly diagnosed paediatric brainstem glioma.
Topics: Adolescent; Antineoplastic Agents, Alkylating; Brain Stem Neoplasms; Canada; Child; Child, Preschool; Combined Modality Therapy; Dacarbazine; Female; Glioma; Humans; Infant; Male; Maximum Tolerated Dose; Pilot Projects; Temozolomide; Thrombocytopenia; Treatment Outcome | 2010 |
Dose escalation study of an anti-thrombocytopenic agent in patients with chemotherapy induced thrombocytopenia.
Topics: Adult; Aged; Antineoplastic Agents; Blood Platelets; Dacarbazine; Dose-Response Relationship, Drug; Doxorubicin; Escherichia coli; Female; Humans; Ifosfamide; Male; Middle Aged; Neoplasms; RNA; Thrombocytopenia; Treatment Outcome | 2010 |
A phase I study of the safety and tolerability of olaparib (AZD2281, KU0059436) and dacarbazine in patients with advanced solid tumours.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Dacarbazine; Drug Administration Schedule; Female; Humans; Male; Maximum Tolerated Dose; Melanoma; Middle Aged; Neoplasms; Neutropenia; Phthalazines; Piperazines; Poly(ADP-ribose) Polymerase Inhibitors; Thrombocytopenia | 2011 |
Phase I clinical trial assessing temozolomide and tamoxifen with concomitant radiotherapy for treatment of high-grade glioma.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemoradiotherapy; Cohort Studies; Dacarbazine; Drug Administration Schedule; Female; Glioblastoma; Glioma; Humans; Karnofsky Performance Status; Male; Maximum Tolerated Dose; Middle Aged; Protein Kinase C; Survival Rate; Tamoxifen; Temozolomide; Thrombocytopenia; Venous Thrombosis; Young Adult | 2012 |
Phase II study of short-course radiotherapy plus concomitant and adjuvant temozolomide in elderly patients with glioblastoma.
Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Chemotherapy, Adjuvant; Dacarbazine; Disease-Free Survival; Dose Fractionation, Radiation; Drug Administration Schedule; Female; Glioblastoma; Humans; Karnofsky Performance Status; Male; Neutropenia; Temozolomide; Thrombocytopenia | 2012 |
Phase II study of Gleevec plus hydroxyurea in adults with progressive or recurrent low-grade glioma.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Benzamides; Brain Neoplasms; Cohort Studies; Dacarbazine; Diarrhea; Disease Progression; Disease-Free Survival; Drug Administration Schedule; Female; Humans; Hydroxyurea; Imatinib Mesylate; Male; Middle Aged; Neoplasm Recurrence, Local; Neutropenia; Oligodendroglioma; Piperazines; Pyrimidines; Temozolomide; Thrombocytopenia; Treatment Outcome | 2012 |
Maintenance biotherapy for metastatic melanoma with interleukin-2 and granulocyte macrophage-colony stimulating factor improves survival for patients responding to induction concurrent biochemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Dacarbazine; Disease-Free Survival; Drug Administration Schedule; Drug Eruptions; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Hyperthyroidism; Immunologic Factors; Interleukin-2; Life Tables; Melanoma; Neoplasm Metastasis; Prospective Studies; Remission Induction; Survival Analysis; Tamoxifen; Thrombocytopenia; Treatment Outcome; Vinblastine | 2002 |
Temozolomide in malignant gliomas of childhood: a United Kingdom Children's Cancer Study Group and French Society for Pediatric Oncology Intergroup Study.
Topics: Adolescent; Antineoplastic Agents, Alkylating; Bone Marrow; Brain Neoplasms; Child; Child, Preschool; Dacarbazine; Female; Glioma; Humans; Male; Temozolomide; Thrombocytopenia | 2002 |
Temozolomide in combination with interferon alpha-2b in patients with metastatic melanoma: a phase I dose-escalation study.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Dacarbazine; Disease-Free Survival; Female; Humans; Interferon alpha-2; Interferon-alpha; Male; Maximum Tolerated Dose; Melanoma; Middle Aged; Neoplasm Staging; Neutropenia; Recombinant Proteins; Skin Neoplasms; Temozolomide; Thrombocytopenia; Treatment Outcome | 2003 |
Phase I study of temozolamide (TMZ) combined with procarbazine (PCB) in patients with gliomas.
Topics: Administration, Oral; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Dacarbazine; Female; Glioblastoma; Glioma; Humans; Male; Middle Aged; Procarbazine; Sleep Stages; Temozolomide; Thrombocytopenia; Treatment Outcome | 2003 |
Pharmacokinetics of temozolomide given three times a day in pediatric and adult patients.
Topics: Administration, Oral; Adolescent; Adult; Antineoplastic Agents, Alkylating; Area Under Curve; Brain Neoplasms; Child; Child, Preschool; Dacarbazine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Half-Life; Humans; Linear Models; Male; Metabolic Clearance Rate; Middle Aged; Neutropenia; Temozolomide; Thrombocytopenia | 2003 |
A phase I (tumour site-specific) study of carboplatin and temozolomide in patients with advanced melanoma.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Carboplatin; Dacarbazine; Drug Interactions; Female; Humans; Male; Maximum Tolerated Dose; Melanoma; Middle Aged; Skin Neoplasms; Temozolomide; Thrombocytopenia | 2003 |
Temozolomide in patients with advanced cancer: phase I and pharmacokinetic study.
Topics: Administration, Oral; Adult; Aged; Alkaline Phosphatase; Alkylating Agents; Area Under Curve; Bilirubin; Capsules; Dacarbazine; Dose-Response Relationship, Drug; Drug Administration Schedule; Half-Life; Humans; Maximum Tolerated Dose; Middle Aged; Neoplasms; Neutropenia; Temozolomide; Thrombocytopenia; Tissue Distribution; Treatment Failure | 2004 |
First-line chemotherapy with cisplatin plus fractionated temozolomide in recurrent glioblastoma multiforme: a phase II study of the Gruppo Italiano Cooperativo di Neuro-Oncologia.
Topics: Adult; Aged; Agranulocytosis; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cisplatin; Dacarbazine; Disease-Free Survival; Drug Administration Schedule; Drug Interactions; Female; Glioblastoma; Humans; Injections, Intravenous; Male; Middle Aged; Neoplasm Recurrence, Local; Temozolomide; Thrombocytopenia; Treatment Outcome | 2004 |
Temozolomide pharmacodynamics in patients with metastatic melanoma: dna damage and activity of repair enzymes O6-alkylguanine alkyltransferase and poly(ADP-ribose) polymerase-1.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Comet Assay; Dacarbazine; DNA Damage; DNA Methylation; DNA Repair; DNA, Neoplasm; Female; Headache; Humans; Lymphocytes; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Neutropenia; O(6)-Methylguanine-DNA Methyltransferase; Poly(ADP-ribose) Polymerases; Temozolomide; Thrombocytopenia; Time Factors; Treatment Outcome | 2005 |
Combined chemoimmunotherapy of metastatic melanoma: a single institution experience.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Dacarbazine; Female; Humans; Interferon alpha-2; Interferon-alpha; Interleukin-2; Male; Melanoma; Nausea; Neutropenia; Recombinant Proteins; Skin Neoplasms; Survival Analysis; Thrombocytopenia; Vinblastine; Vomiting | 2005 |
Phase II trial of temozolomide in children with recurrent high-grade glioma.
Topics: Adolescent; Antineoplastic Agents, Alkylating; Bone Marrow; Brain Neoplasms; Child; Child, Preschool; Dacarbazine; Disease-Free Survival; Drug Administration Schedule; Female; Glioma; Humans; Male; Neoplasm Recurrence, Local; Neutropenia; Temozolomide; Thrombocytopenia; Treatment Outcome | 2006 |
Vinorelbine combined with a protracted course of temozolomide for recurrent brain metastases: a phase I trial.
Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Dacarbazine; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Lung Neoplasms; Lymphopenia; Male; Maximum Tolerated Dose; Middle Aged; Neutropenia; Temozolomide; Thrombocytopenia; Treatment Outcome; Vinblastine; Vinorelbine | 2006 |
A prospective single arm phase II study of dacarbazine and treosulfan as first-line therapy in metastatic uveal melanoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Dacarbazine; Female; Humans; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Prospective Studies; Thrombocytopenia; Uveal Neoplasms | 2006 |
Phase II study of temozolomide in relapsed or refractory high-risk neuroblastoma: a joint Société Française des Cancers de l'Enfant and United Kingdom Children Cancer Study Group-New Agents Group Study.
Topics: Adolescent; Antineoplastic Agents, Alkylating; Bone Marrow; Child; Child, Preschool; Dacarbazine; Female; France; Humans; Infant; Male; Neuroblastoma; Temozolomide; Thrombocytopenia; Treatment Outcome; United Kingdom | 2006 |
A phase I/II study of lomustine and temozolomide in patients with cerebral metastases from malignant melanoma.
Topics: Administration, Oral; Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Lomustine; Male; Maximum Tolerated Dose; Melanoma; Middle Aged; Neutropenia; Temozolomide; Thrombocytopenia; Treatment Failure | 2007 |
Gemcitabine, vinorelbine, and pegylated liposomal doxorubicin (GVD), a salvage regimen in relapsed Hodgkin's lymphoma: CALGB 59804.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Dacarbazine; Deoxycytidine; Disease-Free Survival; Dose-Response Relationship, Drug; Doxorubicin; Gemcitabine; Hodgkin Disease; Humans; Middle Aged; Neutropenia; Patient Selection; Polyethylene Glycols; Salvage Therapy; Survival Analysis; Thrombocytopenia; Treatment Outcome; Vinblastine; Vinorelbine | 2007 |
Treatment of MOPP-refractory Hodgkin's disease with vinblastine, doxorubicin, bleomycin, CCNU, and dacarbazine.
Topics: Adolescent; Adult; Agranulocytosis; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Clinical Trials as Topic; Dacarbazine; Doxorubicin; Drug Resistance; Drug Therapy, Combination; Female; Hodgkin Disease; Humans; Lomustine; Male; Mechlorethamine; Middle Aged; Prednisone; Procarbazine; Prognosis; Thrombocytopenia; Vinblastine; Vincristine | 1983 |
Randomized phase III trial of vinblastine, bleomycin, and cis-dichlorodiammine-platinum versus dacarbazine in malignant melanoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Clinical Trials as Topic; Dacarbazine; Female; Humans; Male; Melanoma; Middle Aged; Mouth Diseases; Neutropenia; Random Allocation; Sepsis; Skin Neoplasms; Thrombocytopenia; Vinblastine | 1984 |
Cyvadic in advanced soft tissue sarcoma: a randomized study comparing two schedules. A study of the EORTC Soft Tissue and Bone Sarcoma Group.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cyclophosphamide; Dacarbazine; Doxorubicin; Female; Follow-Up Studies; Humans; Leukopenia; Male; Middle Aged; Prognosis; Random Allocation; Sarcoma; Soft Tissue Neoplasms; Thrombocytopenia; Vincristine | 1984 |
Combination chemotherapy of advanced colorectal cancer utilizing 5-fluorouracil, semustine, dacarbazine, vincristine, and hydroxyurea: a phase III trial by the Eastern Cooperative Oncology Group (EST: 4275).
Topics: Antineoplastic Agents; Clinical Trials as Topic; Colonic Neoplasms; Dacarbazine; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluorouracil; Humans; Hydroxyurea; Male; Middle Aged; Nausea; Rectal Neoplasms; Semustine; Thrombocytopenia; Vincristine | 1982 |
Randomized study for the treatment of adult advanced Hodgkin's disease: epirubicin, vinblastine, bleomycin, and dacarbazine (EVBD) versus mitoxantrone, vinblastine, bleomycin, and dacarbazine (MVBD).
Topics: Actuarial Analysis; Adolescent; Adult; Agranulocytosis; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chemical and Drug Induced Liver Injury; Dacarbazine; Epirubicin; Female; Hodgkin Disease; Humans; Male; Middle Aged; Mitoxantrone; Prospective Studies; Thrombocytopenia; Treatment Outcome; Ventricular Function, Left; Vinblastine | 1994 |
Doxorubicin versus CYVADIC versus doxorubicin plus ifosfamide in first-line treatment of advanced soft tissue sarcomas: a randomized study of the European Organization for Research and Treatment of Cancer Soft Tissue and Bone Sarcoma Group.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Dacarbazine; Dose-Response Relationship, Drug; Doxorubicin; Female; Humans; Ifosfamide; Leukopenia; Male; Middle Aged; Prognosis; Prospective Studies; Remission Induction; Sarcoma; Survival Analysis; Thrombocytopenia; Vincristine | 1995 |
Cancer Research Campaign phase II trial of temozolomide in metastatic melanoma.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Dacarbazine; Female; Humans; Leukopenia; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Remission Induction; Survival Rate; Temozolomide; Thrombocytopenia; United Kingdom | 1995 |
Chemotherapy with dacarbazine and 5-fluorouracil in advanced medullary thyroid cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Medullary; Dacarbazine; Female; Fluorouracil; Humans; Leukopenia; Male; Middle Aged; Remission Induction; Thrombocytopenia; Thyroid Neoplasms | 1994 |
A phase II study of the sequential administration of dacarbazine and fotemustine in the treatment of cerebral metastases from malignant melanoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazine; Drug Administration Schedule; Female; Humans; Leukopenia; Male; Melanoma; Middle Aged; Nitrosourea Compounds; Organophosphorus Compounds; Thrombocytopenia; Treatment Outcome | 1994 |
Sequential therapy with dacarbazine and carmustine: a phase I study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Dacarbazine; Drug Administration Schedule; Female; Humans; Male; Methyltransferases; Middle Aged; Monocytes; Neoplasms; Neutropenia; O(6)-Methylguanine-DNA Methyltransferase; Thrombocytopenia | 1994 |
Sequential administration of varying doses of dacarbazine and fotemustine in advanced malignant melanoma.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Dacarbazine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Male; Melanoma; Middle Aged; Neutropenia; Nitrosourea Compounds; Organophosphorus Compounds; Respiratory Distress Syndrome; Thrombocytopenia | 1993 |
Cisplatin, dacarbazine, and fotemustine plus interferon alpha in patients with advanced malignant melanoma. A multicenter phase II study of the Italian Cooperative Oncology Group.
Topics: Adult; Aged; Anemia; Antigens, CD; Antigens, Neoplasm; Antigens, Surface; Antineoplastic Combined Chemotherapy Protocols; CD146 Antigen; Cisplatin; Dacarbazine; Female; Fever; Follow-Up Studies; Humans; Interferon-alpha; Male; MART-1 Antigen; Melanoma; Melanoma-Specific Antigens; Membrane Glycoproteins; Middle Aged; Monophenol Monooxygenase; Nausea; Neoplasm Proteins; Neural Cell Adhesion Molecules; Neutropenia; Nitrosourea Compounds; Organophosphorus Compounds; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Survival Analysis; Thrombocytopenia; Treatment Outcome; Vomiting | 2000 |
Temozolomide: the effect of once- and twice-a-day dosing on tumor tissue levels of the DNA repair protein O(6)-alkylguanine-DNA-alkyltransferase.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Area Under Curve; Dacarbazine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Leukocytes, Mononuclear; Male; Middle Aged; Neoplasms; Neutropenia; O(6)-Methylguanine-DNA Methyltransferase; Temozolomide; Thrombocytopenia; Time Factors; Treatment Outcome; Tumor Cells, Cultured | 2001 |
Phase I study of Gliadel wafers plus temozolomide in adults with recurrent supratentorial high-grade gliomas.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Carmustine; Cohort Studies; Dacarbazine; Disease Progression; Dose-Response Relationship, Drug; Drug Implants; Drug Synergism; Female; Glioblastoma; Humans; Magnetic Resonance Imaging; Male; Maximum Tolerated Dose; Middle Aged; Safety; Supratentorial Neoplasms; Temozolomide; Thrombocytopenia; Treatment Outcome | 2001 |
Temozolomide in combination with docetaxel in patients with advanced melanoma: a phase II study of the Hellenic Cooperative Oncology Group.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazine; Disease-Free Survival; Docetaxel; Female; Humans; Infusions, Intravenous; Male; Melanoma; Middle Aged; Neutropenia; Paclitaxel; Skin Neoplasms; Taxoids; Temozolomide; Thrombocytopenia | 2002 |
Vinblastin-carboplatin for metastatic cutaneous melanoma as first-line chemotherapy and in dacarbazine failures: a single-center study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Dacarbazine; Disease Progression; Drug Resistance, Neoplasm; Female; Humans; Male; Melanoma; Middle Aged; Neutropenia; Salvage Therapy; Skin Neoplasms; Thrombocytopenia; Treatment Outcome; Vinblastine | 2001 |
Results with methyl-CCNU and DTIC in metastatic melanoma.
Topics: Brain Neoplasms; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Dacarbazine; Drug Therapy, Combination; Female; Humans; Liver Neoplasms; Male; Melanoma; Neoplasm Metastasis; Nitrosourea Compounds; Prognosis; Remission, Spontaneous; Semustine; Thrombocytopenia; Time Factors; Triazenes | 1977 |
Phase I evaluation of DTIC (NSC-45388) and other studies in malignant melanoma in the Central Oncology Group.
Topics: Carmustine; Clinical Trials as Topic; Dacarbazine; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Leukopenia; Lomustine; Male; Melanoma; Middle Aged; Nausea; Sex Factors; Thrombocytopenia; Triazenes; Vincristine; Vomiting | 1976 |
DTIC (NSC-45388) studies in the southwest oncology group.
Topics: Carmustine; Chlorpromazine; Clinical Trials as Topic; Dacarbazine; Drug Evaluation; Drug Therapy, Combination; Hodgkin Disease; Humans; Leukopenia; Lymphoma; Melanoma; Nausea; Neoplasm Metastasis; Remission, Spontaneous; Thrombocytopenia; Triazenes; Vincristine; Vomiting | 1976 |
Analysis of a series of sixty soft tissue sarcomas in adults treated with a cyclophosphamide-vincristine-adriamycin-dacarbazine (CYVADIC) combination.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cyclophosphamide; Dacarbazine; Doxorubicin; Female; Humans; Leukopenia; Male; Middle Aged; Nausea; Neoplasm Metastasis; Sarcoma; Soft Tissue Neoplasms; Thrombocytopenia; Vincristine | 1985 |
30 other study(ies) available for dacarbazine and Thrombocytopenia
| Article | Year |
|---|---|
Safety of temozolomide use in adult patients with renal dysfunction.
Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioma; Humans; Kidney Diseases; Lymphopenia; Methylhydrazines; Neutropenia; Temozolomide; Thrombocytopenia | 2022 |
Factors predicting temozolomide induced clinically significant acute hematologic toxicity in patients with high-grade gliomas: a clinical audit.
Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cohort Studies; Community-Acquired Infections; Dacarbazine; Female; Glioma; Hematologic Diseases; Humans; Logistic Models; Male; Middle Aged; Neutropenia; Predictive Value of Tests; Temozolomide; Thrombocytopenia | 2013 |
A retrospective study of capecitabine/temozolomide (CAPTEM) regimen in the treatment of metastatic pancreatic neuroendocrine tumors (pNETs) after failing previous therapy.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Dacarbazine; Deoxycytidine; Disease-Free Survival; Drug Administration Schedule; Fatigue; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasm Metastasis; Neuroendocrine Tumors; Neutropenia; Pancreatic Neoplasms; Remission Induction; Retrospective Studies; Temozolomide; Thrombocytopenia; Time Factors; Treatment Outcome | 2013 |
Clinical outcomes of patients with newly diagnosed primary central nervous system lymphoma are comparable on treatment with high-dose methotrexate plus temozolomide and with high-dose methotrexate plus cytarabine: a single-institution experience.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Cytarabine; Dacarbazine; Disease-Free Survival; Dose-Response Relationship, Drug; Female; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Neutropenia; Remission Induction; Temozolomide; Thrombocytopenia; Treatment Outcome; Young Adult | 2014 |
Craniospinal irradiation with concomitant and adjuvant temozolomide--a feasibility assessment of toxicity in patients with glioblastoma with a PNET component.
Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Chemotherapy, Adjuvant; Child; Craniospinal Irradiation; Dacarbazine; Dose Fractionation, Radiation; Feasibility Studies; Female; Follow-Up Studies; Glioblastoma; Humans; Lymphopenia; Male; Neoplasm Staging; Neuroectodermal Tumors, Primitive; Neutropenia; Prognosis; Survival Rate; Temozolomide; Thrombocytopenia; Young Adult | 2016 |
Prolonged and severe thrombocytopenia with pancytopenia induced by radiation-combined temozolomide therapy in a patient with newly diagnosed glioblastoma--analysis of O6-methylguanine-DNA methyltransferase status.
Topics: Antineoplastic Agents, Alkylating; Base Sequence; Blotting, Western; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Female; Glioblastoma; Humans; Magnetic Resonance Imaging; Middle Aged; Neurosurgical Procedures; Pancytopenia; Polymerase Chain Reaction; Radiotherapy; Temozolomide; Thrombocytopenia; Tumor Suppressor Proteins | 2009 |
Risk analysis of severe myelotoxicity with temozolomide: the effects of clinical and genetic factors.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Dacarbazine; Female; Glioma; Glutathione S-Transferase pi; Humans; Male; Middle Aged; NAD(P)H Dehydrogenase (Quinone); Neoplasm Staging; Neutropenia; O(6)-Methylguanine-DNA Methyltransferase; Polymorphism, Single Nucleotide; Prognosis; Retrospective Studies; Risk Factors; Temozolomide; Thrombocytopenia; Young Adult | 2009 |
Management of temozolomide toxicity by nurse practitioners in neuro-oncology.
Topics: Analysis of Variance; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chi-Square Distribution; Dacarbazine; Drug Administration Schedule; Drug Monitoring; Glioma; Humans; Lymphopenia; Nausea; Netherlands; Neutropenia; Nurse Practitioners; Nurse's Role; Nursing Evaluation Research; Oncology Nursing; Prospective Studies; Statistics, Nonparametric; Temozolomide; Thrombocytopenia; Treatment Outcome; Vomiting | 2009 |
Intracerebral hemorrhage secondary to thrombocytopenia in a patient treated with temozolomide.
Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cerebral Hemorrhage; Dacarbazine; Dose-Response Relationship, Drug; Fatal Outcome; Glioma; Humans; Male; Recurrence; Temozolomide; Thrombocytopenia | 2010 |
Immature and absolute platelet count changes and thrombocytopenia in malignant glioma.
Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Austria; Blood Platelets; Dacarbazine; Female; Glioma; Humans; Male; Middle Aged; Platelet Count; Prospective Studies; Sensitivity and Specificity; Temozolomide; Thrombocytopenia; Young Adult | 2011 |
Retrospective comparison of chemoradiotherapy followed by adjuvant chemotherapy, with or without prior gliadel implantation (carmustine) after initial surgery in patients with newly diagnosed high-grade gliomas.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carmustine; Chemoradiotherapy; Chemotherapy, Adjuvant; Dacarbazine; Disease-Free Survival; DNA Modification Methylases; DNA Repair Enzymes; Female; Glioblastoma; Humans; Male; Middle Aged; Neoplasm Proteins; Retrospective Studies; Survival Analysis; Temozolomide; Thrombocytopenia; Tumor Burden; Tumor Suppressor Proteins; Young Adult | 2012 |
[Nimotuzumab in combination with chemotherapy for patients with malignant gliomas].
Topics: Adolescent; Adult; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Child; Cisplatin; Dacarbazine; Disease-Free Survival; Female; Glioblastoma; Glioma; Humans; Infusions, Intravenous; Male; Nausea; Neutropenia; Nimustine; Temozolomide; Teniposide; Thrombocytopenia; Young Adult | 2011 |
Whole abdominopelvic intensity-modulated radiation therapy for desmoplastic small round cell tumor after surgery.
Topics: Abdominal Neoplasms; Adolescent; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Child; Child, Preschool; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Dacarbazine; Desmoplastic Small Round Cell Tumor; Erythrocyte Transfusion; Feasibility Studies; Humans; Hyperthermia, Induced; Interferons; Irinotecan; Liver Neoplasms; Male; Pelvic Neoplasms; Peritoneal Neoplasms; Radiation-Sensitizing Agents; Radiotherapy Dosage; Radiotherapy Planning, Computer-Assisted; Radiotherapy, Intensity-Modulated; Retrospective Studies; Temozolomide; Thrombocytopenia; Vinblastine; Vinorelbine; Young Adult | 2012 |
Impact of antiepileptic drugs on thrombocytopenia in glioblastoma patients treated with standard chemoradiotherapy.
Topics: Anticonvulsants; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Epilepsy; Female; Glioblastoma; Humans; Male; Middle Aged; Neoplasm Grading; Prognosis; Prospective Studies; Survival Rate; Temozolomide; Thrombocytopenia | 2012 |
Cancer-related thrombotic microangiopathy secondary to Von Willebrand factor-cleaving protease deficiency.
Topics: ADAM Proteins; ADAMTS13 Protein; Adenocarcinoma; Anemia, Hemolytic; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; CA-19-9 Antigen; Combined Modality Therapy; Cyclophosphamide; Dacarbazine; Doxorubicin; Esophageal Neoplasms; Fatal Outcome; Female; Humans; Ifosfamide; Jaundice; Metalloendopeptidases; Middle Aged; Neoplasms, Multiple Primary; Neoplasms, Radiation-Induced; Neoplasms, Second Primary; Paraneoplastic Syndromes; Sarcoma; Thrombocytopenia; von Willebrand Factor | 2002 |
[Hodgkin's disease presenting with progressive liver failure].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Dacarbazine; Disease Progression; Doxorubicin; Hodgkin Disease; Humans; Liver Failure; Liver Neoplasms; Lymph Nodes; Lymphatic Metastasis; Male; Neck; Thrombocytopenia; Treatment Outcome; Vinblastine | 2002 |
Higher dosing of temozolomide? Regression of an anaplastic oligoastrocytoma over more than three years.
Topics: Antineoplastic Agents, Alkylating; Astrocytoma; Bone Marrow; Brain Neoplasms; Dacarbazine; Drug Overdose; Humans; Leukopenia; Magnetic Resonance Imaging; Male; Middle Aged; Temozolomide; Thrombocytopenia | 2006 |
[Effect of modified MAID regimen for patients with advanced soft tissue sarcoma].
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Dacarbazine; Doxorubicin; Female; Fibrosarcoma; Follow-Up Studies; Humans; Ifosfamide; Infusions, Intravenous; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Nausea; Neoplasm Staging; Neutropenia; Remission Induction; Rhabdomyosarcoma; Sarcoma, Synovial; Soft Tissue Neoplasms; Survival Rate; Thrombocytopenia; Young Adult | 2006 |
The impact of thrombocytopenia from temozolomide and radiation in newly diagnosed adults with high-grade gliomas.
Topics: Adult; Aged; Anemia; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Female; Glioma; Humans; Male; Middle Aged; Neutropenia; Retrospective Studies; Temozolomide; Thrombocytopenia; Treatment Outcome | 2007 |
Adriamycin, bleomycin, DIC, CCNU, and prednisone (ABDIC) chemotherapy in MOPP-resistant Hodgkin's disease.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Bleomycin; Dacarbazine; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Hodgkin Disease; Humans; Leukopenia; Lomustine; Male; Mechlorethamine; Middle Aged; Prednisone; Procarbazine; Prognosis; Thrombocytopenia; Vincristine | 1980 |
Treatment of advanced soft tissue sarcomas with a modified CYVADIC protocol.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Dacarbazine; Doxorubicin; Hematopoiesis; Humans; Male; Sarcoma; Thrombocytopenia; Vincristine | 1984 |
Phase I trial of intermittent high-dose dacarbazine.
Topics: Adult; Aged; Dacarbazine; Digestive System; Dose-Response Relationship, Drug; Drug Evaluation; Female; Humans; Hypotension; Leukopenia; Male; Middle Aged; Neoplasms; Photosensitivity Disorders; Thrombocytopenia | 1984 |
G-CSF (filgrastim) as an adjunct to MOPP/ABVD therapy in Hodgkin's disease.
Topics: Adult; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Hormonal; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Case-Control Studies; Dacarbazine; Disease-Free Survival; Doxorubicin; Female; Filgrastim; Follow-Up Studies; Granulocyte Colony-Stimulating Factor; Hematinics; Hodgkin Disease; Humans; Male; Mechlorethamine; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Nervous System; Neutropenia; Prednisone; Procarbazine; Recombinant Proteins; Remission Induction; Retrospective Studies; Survival Rate; Thrombocytopenia; Treatment Outcome; Vinblastine; Vincristine | 1997 |
[Clinical results with MGDF].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Dacarbazine; Humans; Leukemia, Myeloid, Acute; Nimustine; Polyethylene Glycols; Randomized Controlled Trials as Topic; Recombinant Proteins; Remission Induction; Thrombocytopenia; Thrombopoietin; Vincristine | 1997 |
Population pharmacokinetics of temozolomide in cancer patients.
Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Body Fluid Compartments; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Dacarbazine; Female; Humans; Male; Middle Aged; Models, Biological; Neoplasms; Neutropenia; Temozolomide; Thrombocytopenia | 2000 |
Treatment of grade III and IV astrocytoma with dimethyl triazeno imidazole carboxamide (DTIC, NSC-45388) alone and in combination with CCNU (NSC-79037) or methyl CCNU (MeCCNU, NSC-95441).
Topics: Adult; Brain Neoplasms; Dacarbazine; Drug Evaluation; Drug Therapy, Combination; Female; Glioblastoma; Humans; Leukopenia; Lomustine; Male; Methylnitrosourea; Middle Aged; Thrombocytopenia; Triazenes | 1975 |
Fotemustine plus dacarbazine for malignant melanoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Dacarbazine; Drug Evaluation; Female; Humans; Leukopenia; Male; Melanoma; Middle Aged; Nitrosourea Compounds; Organophosphorus Compounds; Skin Neoplasms; Thrombocytopenia | 1992 |
Fotemustine plus dacarbazine in advanced stage III malignant melanoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Dacarbazine; Female; Humans; Leukopenia; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Nitrosourea Compounds; Organophosphorus Compounds; Skin Neoplasms; Thrombocytopenia | 1992 |
Sequential chemoimmunotherapy for metastatic melanoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Autoimmune Diseases; Carmustine; Cisplatin; Dacarbazine; Drug Administration Schedule; Female; Humans; Interferon-alpha; Interleukin-2; Male; Melanoma; Middle Aged; Skin Neoplasms; Survival Rate; Tamoxifen; Thrombocytopenia | 1991 |
Combination chemotherapy and hormonal therapy in the treatment of malignant melanoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cisplatin; Dacarbazine; Female; Humans; Kidney Diseases; Leukopenia; Male; Melanoma; Middle Aged; Nausea; Pulmonary Embolism; Skin Neoplasms; Tamoxifen; Thrombocytopenia; Thromboembolism; Vomiting | 1987 |