dacarbazine has been researched along with Pancreatic Neoplasms in 75 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 21 (28.00) | 18.7374 |
1990's | 6 (8.00) | 18.2507 |
2000's | 15 (20.00) | 29.6817 |
2010's | 31 (41.33) | 24.3611 |
2020's | 2 (2.67) | 2.80 |
Authors | Studies |
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Apostolidis, L; Ettrich, TJ; Gress, TM; Hörsch, D; Jann, H; Kegel, T; König, A; Krug, S; Michl, P; Richter, M; Rinke, A; Schrader, J; Steighardt, J | 1 |
Raj, N; Reidy-Lagunes, D; Wu, YL | 1 |
Caroli-Bosc, FX; Cauchin, E; Dumars, C; Foubert, F; Girot, P; Matysiak-Budnik, T; Mosnier, JF; Muzellec, L; Regenet, N; Senellart, H; Touchefeu, Y | 1 |
Allen, PJ; Basturk, O; Capanu, M; Chou, JF; Do, RKG; Horvat, N; Klimstra, DS; Raj, N; Reidy-Lagunes, D; Zhang, L | 1 |
Carilli, A; Pellini Ferreira, B; Vasquez, J | 1 |
Dureja, S; Gupta, SK; Kumar, S; Kumari, J; Malasani, V; Pant, V; Sen, I; Thakral, P; Un, P | 1 |
Bai, CM; Cheng, YJ; Gao, X; Meng, CT; Yan, XY; Ying, HY; Zhou, JF; Zhou, N | 1 |
Brixi, H; Cadiot, G; Cros, J; de Boissieu, P; de Mestier, L; Evrard, C; Hammel, P; Hentic, O; Legoux, JL; Lombard-Bohas, C; Rebours, V; Ruszniewski, P; Tougeron, D; Walter, T | 1 |
Costa, FP; Gumz, B; Pasche, B | 1 |
Allen, J; Blaszkowsky, L; Chan, JA; Gonzalez, M; Kulke, MH; Meyerhardt, J; Regan, E; Ryan, DP; Stuart, K; Wadlow, R; Zheng, H; Zhu, AX | 1 |
Brennan, M; Garcon, MC; Kaley, K; Rodriguez, G; Rodriguez, T; Saif, MW | 1 |
Saif, MW; Tejani, MA | 1 |
Claringbold, PG; Kesavan, M; Turner, JH | 1 |
Blank, A; Dawson, H; Komminoth, P; Pavel, M; Perren, A; Rudolph, T; Schmitt, AM; Vassella, E | 1 |
Rashidi, A; Sorscher, SM | 1 |
Ikeda, M; Kondo, S; Mitsunaga, S; Morizane, C; Ohno, I; Okusaka, T; Sakamoto, Y; Shimizu, S; Takahashi, H; Ueno, H | 1 |
Claringbold, PG; Turner, JH | 1 |
Borghi, D; Busel, AA; Caprera, F; Casale, E; Ciomei, M; Cirla, A; Corti, E; D'Anello, M; Donati, D; Fasolini, M; Felder, ER; Forte, B; Galvani, A; Isacchi, A; Khvat, A; Krasavin, MY; Lupi, R; Montagnoli, A; Orsini, P; Papeo, G; Perego, R; Pesenti, E; Pezzetta, D; Posteri, H; Rainoldi, S; Riccardi-Sirtori, F; Scolaro, A; Sola, F; Zuccotto, F | 1 |
Arcella, A; Ascierto, PA; Cicala, D; De Divitiis, C; Grimaldi, AM; Iaffaioli, RV; Romano, GM; Simeone, E; Tafuto, S; Tatangelo, F; von Arx, C | 1 |
Bedossa, P; Couvelard, A; Cros, J; Gille, N; Hammel, P; Hentic, O; Lévy, P; Maire, F; Paradis, V; Rebours, V; Ruszniewski, P; Theou-Anton, N; Vernerey, D; Zappa, M | 1 |
Gress, TM; Krug, S; Majumder, M; Mueller, D; Rinke, A | 1 |
Black, M; Brelsford, M; Cives, M; Ghayouri, M; Meeker, A; Morse, B; Rizzo, A; Strosberg, J | 1 |
Black, PM; Bracht, LK; Drappatz, J; Hornick, JL; Kesari, S; Kulke, MH; LaFrankie, DC; Meyerhardt, JA; Norden, A; Redston, M; Wen, P | 1 |
Clark, JW; Enzinger, PC; Frauenhoffer, C; Fuchs, CS; Hooshmand, S; Hornick, JL; Kulke, MH; Meyerhardt, JA; Redston, MS; Ryan, DP; Stuart, K | 1 |
Abood, GJ; Go, A; Malhotra, D; Shoup, M | 1 |
de Mestier, L; Dove, P; Hammel, P; Hentic, O; Lévy, P; Ruszniewski, P | 1 |
Chen, DT; Choi, J; Coppola, D; Fine, RL; Helm, J; Kvols, L; Nasir, A; Strosberg, JR | 1 |
Bruneton, D; Cassier, PA; Chayvialle, JA; Hervieu, V; Lombard-Bohas, C; Pilleul, F; Scoazec, JY; Walter, T | 1 |
Ahmed, MM; Gupta, S; Sathishkumar, S | 1 |
Reidy-Lagunes, D; Thornton, R | 1 |
Barlier, A; Barrie, M; Brue, T; Castinetti, F; Conte-Devolx, B; Dufour, H; Morange, I; Philippon, M; Taieb, D | 1 |
Dreyer, C; Faivre, S; Raymond, E | 1 |
Degenhardt, YY; Diskin, SJ; Haglund, E; Maris, JM; Mayes, PA; Moy, C; Toporovskya, Y; Wood, A; Wooster, R | 1 |
Federspiel, B; Hansen, CP; Kjaer, A; Knigge, U; Langer, SW; Olsen, IH; Sørensen, JB | 1 |
Igarashi, H; Ito, T; Jensen, RT; Takayanagi, R | 1 |
Enk, AH; Gronau, M; Hassel, JC; Jäger, D | 1 |
Camp, R; Hemming, AW; Lind, DS | 1 |
Ahmed, MM; Chendil, D; Kokkinakis, DM; Moschel, RC; Pegg, AE | 1 |
Kokkinakis, DM; Liu, X; Neuner, RD | 1 |
Arnold, R; Hofbauer, L; Rinke, A; Schmidt, Ch | 1 |
Clark, JW; Enzinger, PC; Fuchs, CS; Kulke, MH; Michelini, A; Muzikansky, A; Ryan, DP; Stuart, K; Vincitore, M | 1 |
Holen, K | 1 |
Hayashi, H; Igarashi, H; Ito, T; Kawabe, K; Kodama, M; Sakai, H; Takayanagi, R; Yoshinaga, M | 1 |
Lefebvre, PJ; Luyckx, AS | 1 |
Fujita, J; Imura, H; Ishida, H; Kurose, T; Matsukura, M; Seino, Y; Taminato, T | 1 |
Duncan, LA; Fagadau, WR; Marynick, SP | 1 |
Awrich, AE; Fletcher, WS; Peetz, M | 1 |
Badrinath, K; Banerji, M; Dorsch, TR; Lawrence, AM; Prinz, RA; Sparagana, M | 1 |
Duncan, LA; Marynick, SP | 1 |
Foley, JF; Kessinger, A; Lemon, HM | 1 |
Keller, FS; Lieberman, DA; Rösch, J; Wawrukiewicz, AS | 1 |
Dymling, JF; Hallengren, B; Manhem, P; Tennvall, L; Tibblin, S | 1 |
Galle, K; Schweiss, D | 1 |
Kemeny, N | 1 |
Bloom, SR; Hammond, PJ | 1 |
Strohm, WD | 1 |
Feld, R; Hedley, D; Moore, MJ; Oza, A; Siu, LL | 1 |
Hosotani, R; Imamura, M; Kubota, N; Ochi, J; Ohshio, G; Sakahara, H | 1 |
Bassi, C; Bonora, A; Falconi, M; Mansueto, GC; Pederzoli, P; Procacci, C; Sartori, N; Talamini, G | 1 |
Certin, M; D'Alteroche, L; Debbabi, S; Maillard, H; Metman, EH; Viguier, J | 1 |
Mitry, E; Rougier, P | 1 |
Carbone, PP; Cnaan, A; Hahn, RG; Haller, DG; Ramanathan, RK | 1 |
Bajetta, E; Beretta, E; Bombardieri, E; Buzzoni, R; Catena, L; Celio, L; Di Bartolomeo, M; Ferrari, L; Ferrario, E; Martinetti, A; Procopio, G; Seregni, E; Vitali, M | 1 |
Bos, LP; Erdkamp, FL; Knibbeler-van Rossum, CT; Peters, FJ | 1 |
Aoki, TT; Strauss, GM; Weitzman, SA | 1 |
Cruz, AB; Davis, HL; Fletcher, WS; Golomb, FM; Grage, T; Hill, GJ; Johnson, RO; Metter, G; Wilson, WL | 1 |
Totsuka, Y | 1 |
Altimari, AF; Badrinath, K; Prinz, RA; Reisel, HJ | 1 |
Lambrecht, ER; van der Eerden, AH; van der Loos, TL | 1 |
Bonvalet, D; Civatte, J; Jeanmougin, M; Passa, P; Verola, O; Zylberait, D | 1 |
Fujita, J; Horio, T; Imamura, S; Ishida, H; Matsukura, S; Naito, A; Seino, Y; Takahashi, K; Taminato, T; Tobe, T | 1 |
Altimari, AF; Bhoopalam, N; Lange, CL; O'Dorsio, T; Prinz, RA; Sandberg, L | 1 |
Benson, JB; Ferrara, JJ; Fucci, JC | 1 |
Lambers, JC; Lambrecht, ER; van der Loos, TL | 1 |
Buck, M; Kvols, LK | 1 |
11 review(s) available for dacarbazine and Pancreatic Neoplasms
Article | Year |
---|---|
Selecting patients for cytotoxic therapies in gastroenteropancreatic neuroendocrine tumours.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Cell Proliferation; Dacarbazine; Deoxycytidine; Fluorouracil; Humans; Intestinal Neoplasms; Neoplasm Grading; Neoplasm Staging; Neuroendocrine Tumors; Pancreatic Neoplasms; Patient Selection; Prognosis; Stomach Neoplasms; Streptozocin; Temozolomide | 2012 |
Cytotoxic chemotherapy for pancreatic neuroendocrine tumors.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; Dacarbazine; Humans; Neuroendocrine Tumors; Pancreatic Neoplasms; Streptozocin; Temozolomide | 2015 |
The surgical and systemic management of neuroendocrine tumors of the pancreas.
Topics: Antineoplastic Agents, Alkylating; Carcinoma, Neuroendocrine; Catheter Ablation; Chemoembolization, Therapeutic; Combined Modality Therapy; Dacarbazine; Gastrinoma; Humans; Insulinoma; Liver Neoplasms; Octreotide; Pancreatic Neoplasms; Somatostatin; Vipoma | 2009 |
Pancreatic neuroendocrine and carcinoid tumors: what's new, what's old, and what's different?
Topics: Angiogenesis Inhibitors; Antineoplastic Agents; Carcinoid Tumor; Combined Modality Therapy; Dacarbazine; Embolization, Therapeutic; Everolimus; Humans; Immunosuppressive Agents; Indoles; Neuroendocrine Tumors; Pancreatic Neoplasms; Pyrroles; Sirolimus; Streptozocin; Sunitinib; Temozolomide; TOR Serine-Threonine Kinases; Vascular Endothelial Growth Factors; Yttrium Radioisotopes | 2012 |
[Current status and therapeutic strategy for pancreatic neuroendocrine tumors in Japan].
Topics: Antineoplastic Agents; Dacarbazine; Digestive System Surgical Procedures; Everolimus; Humans; Immunosuppressive Agents; Indoles; Japan; Molecular Targeted Therapy; Neuroendocrine Tumors; Pancreatic Neoplasms; Pyrroles; Randomized Controlled Trials as Topic; Sirolimus; Somatostatin; Streptozocin; Sunitinib; Temozolomide | 2012 |
Endocrine tumours of the gastrointestinal tract: Chemotherapy.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Neuroendocrine; Cell Differentiation; Dacarbazine; Disease Progression; Gastrointestinal Neoplasms; Humans; Pancreatic Neoplasms; Streptozocin | 2005 |
Therapeutic and palliative options for diffuse neuroendocrine metastatic disease.
Topics: Antineoplastic Agents; Dacarbazine; Humans; Immunologic Factors; Neoplasm Metastasis; Neuroendocrine Tumors; Nitrosourea Compounds; Palliative Care; Pancreatic Neoplasms; Somatostatin | 2006 |
[The glucagonomas (author's transl)].
Topics: Adenoma, Islet Cell; Adult; Aged; Amino Acids; Anemia; Arginine; Body Weight; Cholesterol; Dacarbazine; Diabetes Mellitus; Diagnosis, Differential; Erythema; Female; Glossitis; Glucagon; Glucagonoma; Humans; Hypoproteinemia; Male; Middle Aged; Nervous System Diseases; Pancreatic Neoplasms; Somatostatin; Streptozocin; Thrombophlebitis; Zinc | 1981 |
The systemic chemotherapy of hepatic metastases.
Topics: Antineoplastic Agents; Breast Neoplasms; Clinical Trials as Topic; Colonic Neoplasms; Dacarbazine; Drug Therapy, Combination; Fluorouracil; Humans; Liver Neoplasms; Lung Neoplasms; Melanoma; Pancreatic Neoplasms; Rectal Neoplasms; Semustine; Stomach Neoplasms | 1983 |
Chemotherapy in the treatment of neuroendocrine malignant tumors.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Dacarbazine; Doxorubicin; Etoposide; Fluorouracil; Gastrointestinal Neoplasms; Humans; Neuroendocrine Tumors; Pancreatic Neoplasms; Streptozocin | 2000 |
Chemotherapy of metastatic carcinoid and islet cell tumors. A review.
Topics: Adenoma, Islet Cell; Antineoplastic Agents; Carcinoid Tumor; Dacarbazine; Drug Therapy, Combination; Humans; Malignant Carcinoid Syndrome; Neoplasm Metastasis; Pancreatic Neoplasms; Streptozocin | 1987 |
11 trial(s) available for dacarbazine and Pancreatic Neoplasms
Article | Year |
---|---|
Ramucirumab in combination with dacarbazine in patients with progressive well-differentiated metastatic pancreatic neuroendocrine tumors (RamuNET): study protocol for a multicenter single-arm trial.
Topics: Adult; Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Dacarbazine; Humans; Middle Aged; Neuroendocrine Tumors; Pancreatic Neoplasms; Pilot Projects; Prospective Studies; Ramucirumab; Time Factors; Vascular Endothelial Growth Factor Receptor-2 | 2021 |
Effect of Endostar combined with chemotherapy in advanced well-differentiated pancreatic neuroendocrine tumors.
Topics: Adult; Aged; Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Dacarbazine; Disease-Free Survival; Endostatins; Female; Fluorouracil; Humans; Induction Chemotherapy; Male; Middle Aged; Neuroendocrine Tumors; Pancreatic Neoplasms; Recombinant Proteins; Temozolomide; Treatment Outcome; Vascular Endothelial Growth Factor A | 2018 |
A prospective, phase 1/2 study of everolimus and temozolomide in patients with advanced pancreatic neuroendocrine tumor.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Dacarbazine; Disease-Free Survival; Drug Administration Schedule; Everolimus; Female; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Neuroendocrine Tumors; Pancreatic Neoplasms; Prospective Studies; Sirolimus; Temozolomide; Treatment Outcome | 2013 |
Hematological toxicity of combined 177Lu-octreotate radiopeptide chemotherapy of gastroenteropancreatic neuroendocrine tumors in long-term follow-up.
Topics: Adult; Aged; Anemia; Antineoplastic Agents; Blood Platelets; Capecitabine; Dacarbazine; Deoxycytidine; Digestive System Neoplasms; Drug Therapy, Combination; Female; Fluorouracil; Follow-Up Studies; Hematologic Diseases; Humans; Incidence; Intestinal Neoplasms; Male; Middle Aged; Neuroendocrine Tumors; Neutrophils; Octreotide; Pancreatic Neoplasms; Radiopharmaceuticals; Randomized Controlled Trials as Topic; Stomach Neoplasms; Temozolomide; Thrombocytopenia; Treatment Outcome | 2014 |
Pancreatic Neuroendocrine Tumor Control: Durable Objective Response to Combination 177Lu-Octreotate-Capecitabine-Temozolomide Radiopeptide Chemotherapy.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Dacarbazine; Female; Humans; Kaplan-Meier Estimate; Longitudinal Studies; Magnetic Resonance Imaging; Male; Middle Aged; Neuroendocrine Tumors; Octreotide; Pancreatic Neoplasms; Temozolomide; Tomography Scanners, X-Ray Computed; Treatment Outcome | 2016 |
Phase II study of temozolomide and thalidomide in patients with metastatic neuroendocrine tumors.
Topics: Adrenal Gland Neoplasms; Adult; Aged; Angiogenesis Inhibitors; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Carcinoid Tumor; Carcinoma, Islet Cell; Dacarbazine; Disease-Free Survival; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Neuroendocrine Tumors; Pancreatic Neoplasms; Pheochromocytoma; Survival Analysis; Temozolomide; Thalidomide; Treatment Outcome | 2006 |
The systemic chemotherapy of hepatic metastases.
Topics: Antineoplastic Agents; Breast Neoplasms; Clinical Trials as Topic; Colonic Neoplasms; Dacarbazine; Drug Therapy, Combination; Fluorouracil; Humans; Liver Neoplasms; Lung Neoplasms; Melanoma; Pancreatic Neoplasms; Rectal Neoplasms; Semustine; Stomach Neoplasms | 1983 |
A phase II study of temozolomide in advanced untreated pancreatic cancer.
Topics: Adenocarcinoma; Aged; Antineoplastic Agents, Alkylating; Dacarbazine; Humans; Middle Aged; Pancreatic Neoplasms; Temozolomide; Treatment Outcome | 1998 |
Role of chemoembolization in synchronous liver metastases from pancreatic endocrine tumours.
Topics: Actuarial Analysis; Adenoma, Islet Cell; Adolescent; Adult; Aged; Aged, 80 and over; Angiography; Chemoembolization, Therapeutic; Combined Modality Therapy; Dacarbazine; Female; Follow-Up Studies; Humans; Iodized Oil; Liver Neoplasms; Male; Middle Aged; Palliative Care; Pancreatic Neoplasms; Survival Rate; Tomography, X-Ray Computed; Treatment Outcome | 1999 |
Phase II trial of dacarbazine (DTIC) in advanced pancreatic islet cell carcinoma. Study of the Eastern Cooperative Oncology Group-E6282.
Topics: Adenoma, Islet Cell; Adult; Aged; Antineoplastic Agents; Dacarbazine; Female; Humans; Male; Middle Aged; Neoplasm Staging; Pancreatic Neoplasms; Survival Analysis | 2001 |
Efficacy of a chemotherapy combination for the treatment of metastatic neuroendocrine tumours.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Dacarbazine; Disease Progression; Epirubicin; Female; Fluorouracil; Humans; Infusions, Intravenous; Lung Neoplasms; Male; Middle Aged; Neuroendocrine Tumors; Pancreatic Neoplasms; Stomach Neoplasms; Survival Analysis; Treatment Outcome | 2002 |
54 other study(ies) available for dacarbazine and Pancreatic Neoplasms
Article | Year |
---|---|
Exceptional Responses After Cessation of Therapy With Alkylating Agents for Pancreatic Neuroendocrine Tumors.
Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Dacarbazine; Female; Humans; Male; Middle Aged; Neoadjuvant Therapy; Neuroendocrine Tumors; Outcome Assessment, Health Care; Pancreatic Neoplasms; Progression-Free Survival; Temozolomide; Withholding Treatment | 2020 |
Short article: Evaluation of O6-methylguanine-DNA methyltransferase as a predicting factor of response to temozolomide-based chemotherapy in well-differentiated metastatic pancreatic neuroendocrine tumors.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Cell Differentiation; Dacarbazine; Disease Progression; Disease-Free Survival; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Female; France; Humans; Immunohistochemistry; Kaplan-Meier Estimate; Male; Middle Aged; Neuroendocrine Tumors; Pancreatic Neoplasms; Patient Selection; Polymerase Chain Reaction; Precision Medicine; Predictive Value of Tests; Promoter Regions, Genetic; Retrospective Studies; Temozolomide; Time Factors; Treatment Outcome; Tumor Suppressor Proteins | 2017 |
O6-Methylguanine DNA Methyltransferase Status Does Not Predict Response or Resistance to Alkylating Agents in Well-Differentiated Pancreatic Neuroendocrine Tumors.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Cell Differentiation; Child; Dacarbazine; Databases, Factual; Disease Progression; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Drug Resistance, Neoplasm; Female; Humans; Immunohistochemistry; Kaplan-Meier Estimate; Male; Middle Aged; Neoplasm Grading; Neuroendocrine Tumors; Pancreatic Neoplasms; Pharmacogenetics; Promoter Regions, Genetic; Sequence Analysis, DNA; Temozolomide; Time Factors; Treatment Outcome; Tumor Suppressor Proteins; Young Adult | 2017 |
Metastatic Hepatoid Carcinoma of the Pancreas: First Description of Treatment With Capecitabine and Temozolomide.
Topics: Adult; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Biopsy; Capecitabine; Carcinoma, Hepatocellular; Dacarbazine; Glucagon; Glucagonoma; Humans; Jaundice; Liver; Male; Neoplasm Metastasis; Pancreatic Neoplasms; Prognosis; Temozolomide; Treatment Outcome | 2017 |
Dosimetric analysis of patients with gastro entero pancreatic neuroendocrine tumors (NETs) treated with PRCRT (peptide receptor chemo radionuclide therapy) using Lu-177 DOTATATE and capecitabine/temozolomide (CAP/TEM).
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Capecitabine; Case-Control Studies; Chemoradiotherapy; Dacarbazine; Drug Administration Schedule; Female; Humans; Intestinal Neoplasms; Liver; Male; Middle Aged; Neuroendocrine Tumors; Octreotide; Organometallic Compounds; Pancreatic Neoplasms; Prospective Studies; Radiation-Sensitizing Agents; Radiometry; Radiopharmaceuticals; Radiotherapy Dosage; Spleen; Stomach Neoplasms; Temozolomide; Tissue Distribution | 2018 |
Comparison of Temozolomide-Capecitabine to 5-Fluorouracile-Dacarbazine in 247 Patients with Advanced Digestive Neuroendocrine Tumors Using Propensity Score Analyses.
Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Dacarbazine; Digestive System Neoplasms; Disease-Free Survival; Female; Gastrointestinal Neoplasms; Humans; Male; Middle Aged; Neuroendocrine Tumors; Pancreatic Neoplasms; Propensity Score; Temozolomide | 2019 |
A retrospective study of capecitabine/temozolomide (CAPTEM) regimen in the treatment of metastatic pancreatic neuroendocrine tumors (pNETs) after failing previous therapy.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Dacarbazine; Deoxycytidine; Disease-Free Survival; Drug Administration Schedule; Fatigue; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasm Metastasis; Neuroendocrine Tumors; Neutropenia; Pancreatic Neoplasms; Remission Induction; Retrospective Studies; Temozolomide; Thrombocytopenia; Time Factors; Treatment Outcome | 2013 |
Pancreatic neuroendocrine tumors: does chemotherapy work?
Topics: Algorithms; Antineoplastic Agents; Capecitabine; Dacarbazine; Deoxycytidine; Drug Therapy; Drug Therapy, Combination; Fluorouracil; Humans; Neuroendocrine Tumors; Pancreatic Neoplasms; Temozolomide; Treatment Outcome | 2014 |
Prognostic and predictive roles of MGMT protein expression and promoter methylation in sporadic pancreatic neuroendocrine neoplasms.
Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Biomarkers, Pharmacological; Biomarkers, Tumor; Dacarbazine; Disease-Free Survival; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Female; Follow-Up Studies; Humans; Male; Middle Aged; Neuroendocrine Tumors; Pancreatic Neoplasms; Prognosis; Promoter Regions, Genetic; Temozolomide; Tumor Suppressor Proteins; Ubiquitin-Protein Ligases | 2014 |
Temozolomide-associated myelodysplasia 6 years after treatment of a patient with pancreatic neuroendocrine tumor.
Topics: Antineoplastic Agents, Alkylating; Dacarbazine; Humans; Male; Middle Aged; Myelodysplastic Syndromes; Neuroendocrine Tumors; Pancreatic Neoplasms; Temozolomide; Time Factors | 2015 |
Discovery of 2-[1-(4,4-Difluorocyclohexyl)piperidin-4-yl]-6-fluoro-3-oxo-2,3-dihydro-1H-isoindole-4-carboxamide (NMS-P118): A Potent, Orally Available, and Highly Selective PARP-1 Inhibitor for Cancer Therapy.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Biological Availability; Cell Proliferation; Dacarbazine; Drug Screening Assays, Antitumor; Female; Heterografts; High-Throughput Screening Assays; Humans; Isoindoles; Mice, Inbred BALB C; Mice, Nude; Microsomes, Liver; Models, Molecular; Neoplasm Transplantation; Pancreatic Neoplasms; Piperidines; Poly(ADP-ribose) Polymerase Inhibitors; Rats, Sprague-Dawley; Structure-Activity Relationship; Temozolomide; Triple Negative Breast Neoplasms | 2015 |
Metronomic temozolomide as second line treatment for metastatic poorly differentiated pancreatic neuroendocrine carcinoma.
Topics: Administration, Metronomic; Animals; Carcinoma, Neuroendocrine; Cell Differentiation; Dacarbazine; Female; Humans; Middle Aged; Neoplasm Metastasis; Pancreatic Neoplasms; Temozolomide; Tomography, X-Ray Computed | 2016 |
MGMT expression predicts response to temozolomide in pancreatic neuroendocrine tumors.
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Dacarbazine; Disease-Free Survival; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Female; Humans; Male; Middle Aged; Neuroendocrine Tumors; Pancreatic Neoplasms; Prognosis; Promoter Regions, Genetic; Temozolomide; Treatment Outcome; Tumor Suppressor Proteins | 2016 |
Low dose DTIC is effective and safe in pretreated patients with well differentiated neuroendocrine tumors.
Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Dacarbazine; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Neuroendocrine Tumors; Pancreatic Neoplasms; Retrospective Studies; Survival Analysis; Treatment Outcome | 2016 |
Analysis of potential response predictors to capecitabine/temozolomide in metastatic pancreatic neuroendocrine tumors.
Topics: Adaptor Proteins, Signal Transducing; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Co-Repressor Proteins; Dacarbazine; DNA Modification Methylases; DNA Repair Enzymes; Female; Humans; Male; Middle Aged; Molecular Chaperones; Neuroendocrine Tumors; Nuclear Proteins; Pancreatic Neoplasms; Telomere; Temozolomide; Treatment Outcome; Tumor Suppressor Proteins; X-linked Nuclear Protein | 2016 |
DNA repair enzyme expression and differential response to temozolomide in a patient with both glioblastoma and metastatic pancreatic neuroendocrine tumor.
Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease Progression; DNA Repair Enzymes; Fatal Outcome; Glioblastoma; Humans; Liver Neoplasms; Male; Middle Aged; Neuroendocrine Tumors; Pancreatic Neoplasms; Remission Induction; Temozolomide | 2008 |
O6-methylguanine DNA methyltransferase deficiency and response to temozolomide-based therapy in patients with neuroendocrine tumors.
Topics: Antineoplastic Agents, Alkylating; Carcinoid Tumor; Dacarbazine; Disease-Free Survival; Female; Humans; Male; Middle Aged; Neuroendocrine Tumors; O(6)-Methylguanine-DNA Methyltransferase; Pancreatic Neoplasms; Temozolomide; Treatment Outcome | 2009 |
[Dramatic efficacy of chemotherapy with 5-fluorouracil and dacarbazine in a patient with metastatic glucagonoma and cardiac insufficiency].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cardiomyopathy, Dilated; Dacarbazine; Female; Fluorouracil; Glucagonoma; Humans; Liver Neoplasms; Pancreatic Neoplasms | 2010 |
First-line chemotherapy with capecitabine and temozolomide in patients with metastatic pancreatic endocrine carcinomas.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Carcinoma, Islet Cell; Dacarbazine; Deoxycytidine; Disease-Free Survival; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasm Metastasis; Pancreatic Neoplasms; Retrospective Studies; Temozolomide; Tomography, X-Ray Computed | 2011 |
Evaluation of the combination 5-fluorouracil, dacarbazine, and epirubicin in patients with advanced well-differentiated neuroendocrine tumors.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Dacarbazine; Drug Administration Schedule; Epirubicin; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Kaplan-Meier Estimate; Lung Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Neuroendocrine Tumors; Pancreatic Neoplasms; Retrospective Studies; Treatment Outcome | 2010 |
Influence of cell cycle checkpoints and p53 function on the toxicity of temozolomide in human pancreatic cancer cells.
Topics: Animals; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Dacarbazine; DNA Mismatch Repair; Fibroblasts; Guanine; Humans; In Situ Nick-End Labeling; Mice; O(6)-Methylguanine-DNA Methyltransferase; Pancreatic Neoplasms; Temozolomide; Tumor Suppressor Protein p53 | 2010 |
Long-term control of a MEN1 prolactin secreting pituitary carcinoma after temozolomide treatment.
Topics: Adult; Antineoplastic Agents; Carcinoma; Combined Modality Therapy; Cranial Irradiation; Dacarbazine; Dopamine Agonists; Hormone Replacement Therapy; Humans; Hyperprolactinemia; Hypophysectomy; Hypopituitarism; Male; Multiple Endocrine Neoplasia Type 1; Mutation, Missense; Neoplasm Recurrence, Local; Ophthalmoplegia; Pancreatic Neoplasms; Parathyroid Neoplasms; Pituitary Apoplexy; Pituitary Neoplasms; Prolactin; Proto-Oncogene Proteins; Radiotherapy, Adjuvant; Remission Induction; Spinal Neoplasms; Temozolomide | 2012 |
Targeting neuroendocrine tumor: mixing standard options with novel therapies.
Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Combined Modality Therapy; Dacarbazine; Disease Progression; Drug Resistance, Neoplasm; Humans; Indoles; Medical Oncology; Neoplasm Metastasis; Neuroendocrine Tumors; Pancreatic Neoplasms; Pyrroles; Sunitinib; Temozolomide; Treatment Outcome | 2012 |
Mitogen-activated protein kinase (MEK/ERK) inhibition sensitizes cancer cells to centromere-associated protein E inhibition.
Topics: Antineoplastic Agents; Apoptosis; Benzamides; Biomarkers, Tumor; Bridged Bicyclo Compounds, Heterocyclic; Camptothecin; Cell Line, Tumor; Cell Proliferation; Chromosomal Proteins, Non-Histone; Colonic Neoplasms; Dacarbazine; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Humans; Irinotecan; Lung Neoplasms; M Phase Cell Cycle Checkpoints; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 3; Neuroblastoma; Pancreatic Neoplasms; RNA Interference; RNA, Small Interfering; Sarcosine; Temozolomide | 2013 |
Temozolomide as second or third line treatment of patients with neuroendocrine carcinomas.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Dacarbazine; Disease Progression; Female; Humans; Immunohistochemistry; Kaplan-Meier Estimate; Ki-67 Antigen; Male; Middle Aged; Neuroendocrine Tumors; Pancreatic Neoplasms; Prognosis; Retrospective Studies; Temozolomide | 2012 |
Necrolytic migratory erythema in a patient with neuroendocrine carcinoma.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biopsy, Needle; Capecitabine; Carcinoma, Neuroendocrine; Dacarbazine; Deoxycytidine; Diagnosis, Differential; Drug Eruptions; Female; Fluorouracil; Follow-Up Studies; Humans; Immunohistochemistry; Necrolytic Migratory Erythema; Neoplasm Staging; Pancreatic Neoplasms; Paraneoplastic Syndromes; Risk Assessment; Temozolomide; Treatment Outcome | 2013 |
Combined liver and pancreas resection with biochemotherapy for metastatic ocular melanoma.
Topics: Antineoplastic Agents, Alkylating; Dacarbazine; Eye Enucleation; Female; Hepatectomy; Humans; Interferon-alpha; Liver Neoplasms; Lymph Node Excision; Lymphatic Metastasis; Melanoma; Middle Aged; Pancreatectomy; Pancreatic Neoplasms; Uveal Neoplasms | 2002 |
Sensitization of pancreatic tumor xenografts to carmustine and temozolomide by inactivation of their O6-Methylguanine-DNA methyltransferase with O6-benzylguanine or O6-benzyl-2'-deoxyguanosine.
Topics: Alkylating Agents; Animals; Antineoplastic Agents, Alkylating; Carmustine; Cell Line, Tumor; Dacarbazine; Deoxyguanosine; DNA Repair; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanine; Humans; Male; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; O(6)-Methylguanine-DNA Methyltransferase; Pancreatic Neoplasms; Temozolomide; Time Factors | 2003 |
Modulation of cell cycle and gene expression in pancreatic tumor cell lines by methionine deprivation (methionine stress): implications to the therapy of pancreatic adenocarcinoma.
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Blotting, Western; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Dacarbazine; Fluorouracil; Gene Expression; Gene Expression Profiling; Humans; Methionine; Neoplasm Proteins; O(6)-Methylguanine-DNA Methyltransferase; Oligonucleotide Array Sequence Analysis; Pancreatic Neoplasms; Phosphorylation; Retinoblastoma Protein; Signal Transduction; Temozolomide; Transforming Growth Factor beta | 2005 |
Successful management of multiple liver metastases from pancreatic neuroendocrine tumor by hepatic arterial administration of cisplatin powder.
Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Dacarbazine; Deoxycytidine; Drug Carriers; Female; Gemcitabine; Hepatic Artery; Humans; Infusions, Intra-Arterial; Iodized Oil; Liver Neoplasms; Middle Aged; Neuroendocrine Tumors; Pancreatic Neoplasms; Pancreaticoduodenectomy; Powders; Remission Induction | 2007 |
Successful treatment of metastatic glucagonoma with dacarbazine.
Topics: Adenoma, Islet Cell; Dacarbazine; Glucagonoma; Humans; Liver Neoplasms; Male; Middle Aged; Pancreatic Neoplasms | 1984 |
Malignant glucagonoma syndrome: response to chemotherapy.
Topics: Adenoma, Islet Cell; Dacarbazine; Female; Glucagon; Humans; Middle Aged; Pancreatic Neoplasms; Streptozocin; Syndrome | 1980 |
Dimethyltriazenoimidazole carboxamide therapy of islet cell carcinoma of the pancreas.
Topics: Adenoma, Islet Cell; Adult; Aged; Dacarbazine; Female; Glucagon; Humans; Male; Middle Aged; Pancreatic Neoplasms | 1981 |
Operative and chemotherapeutic management of malignant glucagon-producing tumors.
Topics: Adenoma, Islet Cell; Body Weight; Dacarbazine; Dermatitis; Diabetes Mellitus; Glucagon; Glucagonoma; Humans; Male; Middle Aged; Pancreatectomy; Pancreatic Neoplasms; Scotoma; Syndrome | 1981 |
Glucagonoma and dacarbazine.
Topics: Adenoma, Islet Cell; Dacarbazine; Glucagonoma; Humans; Pancreatic Neoplasms | 1982 |
Therapy of malignant APUD cell tumors. Effectiveness of DTIC.
Topics: Adenoma, Islet Cell; Adult; Aged; Apudoma; Carcinoid Tumor; Carcinoma; Dacarbazine; Female; Humans; Ileal Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Pancreatic Neoplasms; Thyroid Neoplasms | 1983 |
Glucagonoma and its angiographic diagnosis.
Topics: Adenoma, Islet Cell; Adult; Aged; Angiography; Antineoplastic Agents; Dacarbazine; Drug Therapy, Combination; Female; Fluorouracil; Glucagonoma; Humans; Liver Neoplasms; Male; Middle Aged; Pancreatic Neoplasms; Streptozocin; Tubercidin | 1982 |
Unsuccessful DTIC treatment of a patient with glucagonoma syndrome.
Topics: Adenoma, Islet Cell; Dacarbazine; Drug Therapy, Combination; Fluorouracil; Glucagonoma; Humans; Liver Neoplasms; Male; Middle Aged; Pancreatic Neoplasms; Streptozocin | 1983 |
[The glucagonoma syndrome--a not-so-well-known cutaneous paraneoplastic condition. Case report].
Topics: Adenoma, Islet Cell; Adrenal Cortex Hormones; Dacarbazine; Glucagonoma; Humans; Male; Middle Aged; Pancreatic Neoplasms; Precancerous Conditions; PUVA Therapy; Skin Neoplasms; Syndrome | 1984 |
Gut neuroendocrine tumors.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Dacarbazine; Diazoxide; Etoposide; Fluorouracil; Gastrointestinal Neoplasms; Humans; Interferon-alpha; Neuroendocrine Tumors; Octreotide; Omeprazole; Pancreatic Neoplasms; Streptozocin | 1994 |
[Paraneoplastic spastic tetraparesis in glucagonoma syndrome. Successful therapy with octreotide, dacarbazine and interferon-alpha].
Topics: Adult; Chemotherapy, Adjuvant; Combined Modality Therapy; Dacarbazine; Diagnostic Imaging; Glucagon; Glucagonoma; Humans; Interferon-alpha; Liver Neoplasms; Male; Octreotide; Pancreatectomy; Pancreatic Neoplasms; Paraneoplastic Syndromes; Quadriplegia | 1996 |
Gastrinoma with multiple liver metastases: effectiveness of dacarbazine (DTIC) therapy.
Topics: Aged; Antineoplastic Agents, Alkylating; Dacarbazine; Female; Gastrinoma; Humans; Liver Neoplasms; Male; Middle Aged; Pancreatic Neoplasms; Zollinger-Ellison Syndrome | 1998 |
[Chemoembolization followed by systemic chemotherapy with dacarbazine for a metastatic glucagonoma].
Topics: Aged; Antineoplastic Agents, Alkylating; Chemoembolization, Therapeutic; Dacarbazine; Glucagonoma; Humans; Male; Pancreatic Neoplasms | 2000 |
Unusual presentation of Hodgkin's lymphoma.
Topics: Abdominal Pain; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cholangiopancreatography, Endoscopic Retrograde; Dacarbazine; Doxorubicin; Female; Hodgkin Disease; Humans; Pancreatic Neoplasms; Prognosis; Vinblastine | 2002 |
Dimethyltriazenoimidazole carboxamide therapy of malignant glucagonoma.
Topics: Adult; Dacarbazine; Glucagon; Humans; Male; Pancreatic Neoplasms; Syndrome; Triazenes | 1979 |
Multimodal surgical adjuvant therapy for a broad spectrum of tumors in humans.?
Topics: Adult; Altretamine; Antineoplastic Agents; Bone Neoplasms; Breast Neoplasms; Carmustine; Colonic Neoplasms; Cyclophosphamide; Dacarbazine; Doxorubicin; Drug Evaluation; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Lomustine; Lung Neoplasms; Male; Melanoma; Mitolactol; Neoplasms; Osteosarcoma; Pancreatic Neoplasms; Rectal Neoplasms; Vincristine | 1976 |
[Glucagonoma and somatostatinoma].
Topics: Dacarbazine; Female; Glucagon; Glucagonoma; Glucose; Humans; Liver; Middle Aged; Octreotide; Pancreatic Neoplasms; Somatostatinoma; Streptozocin | 1991 |
DTIC therapy in patients with malignant intra-abdominal neuroendocrine tumors.
Topics: Abdominal Neoplasms; Adenoma, Islet Cell; Adult; Animals; Carcinoid Tumor; Dacarbazine; Female; Glucagonoma; Humans; Ileal Neoplasms; Male; Middle Aged; Pancreatic Neoplasms; Retroperitoneal Neoplasms | 1987 |
Retrobulbar neuritis as the first sign of the glucagonoma syndrome.
Topics: Adenoma, Islet Cell; Dacarbazine; Diagnosis, Differential; Eye; Glucagonoma; Humans; Male; Middle Aged; Neuritis; Pancreatic Neoplasms; Scotoma; Vision Disorders | 1987 |
[Metastatic glucagonoma. Complete remission by dacarbazine (5 years' recession)].
Topics: Adenoma, Islet Cell; Dacarbazine; Follow-Up Studies; Glucagonoma; Humans; Liver Neoplasms; Male; Middle Aged; Pancreatectomy; Pancreatic Neoplasms; Skin Diseases; Splenectomy | 1988 |
A functional study of a case of glucagonoma exhibiting typical glucagonoma syndrome.
Topics: Adenoma, Islet Cell; Arginine; Blood Glucose; Chromatography, Gel; Dacarbazine; Endocrine Glands; Gastric Inhibitory Polypeptide; Glucagon; Glucagonoma; Glucose Tolerance Test; Humans; Insulin; Male; Middle Aged; Pancreatic Neoplasms; Secretin; Somatostatin | 1986 |
Use of a somatostatin analog (SMS 201-995) in the glucagonoma syndrome.
Topics: Adenoma, Islet Cell; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Dacarbazine; Diabetes Mellitus; Drug Evaluation; Erythema; Female; Fluorouracil; Glucagon; Glucagonoma; Humans; Liver Neoplasms; Male; Middle Aged; Octreotide; Pancreatic Neoplasms; Somatostatin; Streptozocin; Syndrome | 1986 |
Metastatic pancreatic islet cell carcinoma causing manifestations of glucagon and gastrin hypersecretion.
Topics: Adenoma, Islet Cell; Dacarbazine; Gastrins; Glucagon; Humans; Male; Middle Aged; Neoplasm Metastasis; Pancreatic Neoplasms; Zollinger-Ellison Syndrome | 1985 |
Successful treatment of glucagonoma-related necrolytic migratory erythema with dacarbazine.
Topics: Adenoma, Islet Cell; Dacarbazine; Erythema; Glucagonoma; Humans; Male; Middle Aged; Pancreatic Neoplasms | 1987 |