dacarbazine has been researched along with Necrosis in 29 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (20.69) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 9 (31.03) | 29.6817 |
| 2010's | 14 (48.28) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cloughesy, TF; Faiq, N; Green, R; Green, S; Hu, J; Lai, A; Mellinghoff, I; Nghiemphu, PL; Yu, A | 1 |
| Bonacorso, HG; Costa Nunes, F; Creczynski-Pasa, TB; de Melo, LJ; Feitosa, SC; Martins, MAP; Rode, M; Silva, AH; Silva, LB; Winter, E; Zanatta, N | 1 |
| Bright, JJ; Kanakasabai, S; Rafi, MM; Reyes, MD | 1 |
| Hara, R; Hasegawa, Y; Hatano, K; Iuchi, T; Kawasaki, K; Kodama, T; Sakaida, T; Yokoi, S | 1 |
| Debatin, KM; Dwucet, A; Halatsch, ME; Karpel-Massler, G; Kast, RE; Nonnenmacher, L; Westhoff, MA; Wirtz, CR | 1 |
| Buslei, R; Derer, A; Fietkau, R; Frey, B; Gaipl, US; Muth, C; Rubner, Y; Sieber, R; Strnad, A | 1 |
| Del Basso De Caro, ML; Elefante, A; Giamundo, A; Maiuri, F; Mariniello, G; Pacelli, R; Peca, C; Vergara, P | 1 |
| Belohlavek, C; Christmann, M; Jöst, E; Kaina, B; Lennerz, V; Naumann, SC; Roos, WP; Schmidt, CW | 1 |
| Akmansu, M; Benekli, M; Buyukberber, S; Coskun, U; Kaya, AO; Oner, Y; Ozturk, B; Uncu, D; Yaman, E; Yildiz, R | 1 |
| Dianov, GL; Digweed, M; Eich, M; Kaina, B; Roos, WP | 1 |
| Chen, C; Damek, DM; Franklin, W; Gaspar, LE; Kavanagh, BD; Kleinschmidt-DeMasters, BK; Lillehei, K; Olsen, C; Rusthoven, KE; Waziri, A | 1 |
| Bölke, E; Budach, W; Gerber, PA; Hoffmann, TK; Lammering, G; Matuschek, C; Nawatny, J; Orth, K; Peiper, M; Rusnak, E | 1 |
| Jakubowicz-Gil, J; Langner, E; Rzeski, W | 1 |
| Boxerman, J; Jeyapalan, S; Raghavan, D; Rogg, J | 1 |
| Lu, JQ; Mehta, V; Patel, S; Pugh, J; Wilson, BA | 1 |
| McGrath, SE; Walker-Bone, K; Webb, A | 1 |
| Isobe, T; Kato, Y; Koga, M; Mizuguchi, J; Saito, M; Shibuya, H; Toyota, H; Tsuboi, R | 1 |
| Cannavò, E; D'Atri, S; Falchetti, R; Fuggetta, MP; Lanzilli, G; Ravagnan, G; Tricarico, M; Zambruno, G | 1 |
| Antipas, VP; Stamatakos, GS; Uzunoglu, NK | 1 |
| Chalmers, L; Chamberlain, MC; Glantz, MJ; Sloan, AE; Van Horn, A | 1 |
| Andreoli, A; Bartolini, S; Bertorelle, R; Blatt, V; Brandes, AA; Calbucci, F; Ermani, M; Franceschi, E; Frezza, G; Leonardi, M; Pession, A; Spagnolli, F; Tallini, G; Tosoni, A | 1 |
| Brandsma, D; Sminia, P; Stalpers, L; Taal, W; van den Bent, MJ | 1 |
| Bogden, AE; Cobb, WR; Costanza, ME; Griffin, W; Reich, SD | 1 |
| Erichsen, C; Jönsson, PE | 1 |
| Doepfmer, K; Féaux de Lacroix, W; Groth, W; Hauk, H; Runne, U; Wacker, D | 1 |
| Arseneau, JC; Asbury, RF; Descalzi, ME; Ratcliffe, RL; Rosenthal, SN | 1 |
| Gore, M; Stebbing, J; Thomas, M | 1 |
| Joensuu, H; Nikkanen, V; Söderström, KO | 1 |
| Bella, M; Bocchi, P; Ceci, G; Cocconi, G; Gabrielli, M; Melissari, M | 1 |
2 review(s) available for dacarbazine and Necrosis
| Article | Year |
|---|---|
Bevacizumab as a treatment option for radiation-induced cerebral necrosis.
Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Alkylating; Astrocytoma; Bevacizumab; Blood-Brain Barrier; Brain; Brain Edema; Brain Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Dacarbazine; Humans; Male; Necrosis; Neoplasm Recurrence, Local; Neurologic Examination; Radiation Injuries; Radiosurgery; Radiotherapy Dosage; Radiotherapy Planning, Computer-Assisted; Radiotherapy, Adjuvant; Temozolomide; Vascular Endothelial Growth Factor A; Young Adult | 2011 |
Clinical features, mechanisms, and management of pseudoprogression in malignant gliomas.
Topics: Acute Disease; Antineoplastic Agents, Alkylating; Apoptosis; Brain Edema; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Diagnosis, Differential; Diagnostic Imaging; Disease Progression; DNA Modification Methylases; DNA Repair Enzymes; Endothelial Cells; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Glioma; Humans; Magnetic Resonance Imaging; Necrosis; Neoplasm Recurrence, Local; Patient Selection; Radiation Injuries; Radiotherapy, Adjuvant; Risk Assessment; Temozolomide; Treatment Outcome; Tumor Suppressor Proteins; Vascular Endothelial Growth Factor A | 2008 |
3 trial(s) available for dacarbazine and Necrosis
| Article | Year |
|---|---|
Report of safety of pulse dosing of lapatinib with temozolomide and radiation therapy for newly-diagnosed glioblastoma in a pilot phase II study.
Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Drug Administration Schedule; Female; Glioblastoma; Humans; Karnofsky Performance Status; Lapatinib; Male; Middle Aged; Necrosis; Pilot Projects; Quinazolines; Temozolomide; Thrombocytopenia; Treatment Outcome | 2017 |
Phase 2 trial of hypofractionated high-dose intensity modulated radiation therapy with concurrent and adjuvant temozolomide for newly diagnosed glioblastoma.
Topics: Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Cause of Death; Chemotherapy, Adjuvant; Dacarbazine; Disease-Free Survival; Dose Fractionation, Radiation; Drug Administration Schedule; Female; Glioblastoma; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Necrosis; Neoplasm, Residual; Prospective Studies; Radiation Injuries; Radiotherapy, Intensity-Modulated; Temozolomide | 2014 |
Early necrosis following concurrent Temodar and radiotherapy in patients with glioblastoma.
Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Dacarbazine; Female; Glioblastoma; Humans; Male; Middle Aged; Necrosis; Radiation-Sensitizing Agents; Radiotherapy Dosage; Temozolomide; Treatment Outcome | 2007 |
24 other study(ies) available for dacarbazine and Necrosis
| Article | Year |
|---|---|
Tacrine derivatives stimulate human glioma SF295 cell death and alter important proteins related to disease development: An old drug for new targets.
Topics: Apoptosis; Caspases; Cell Cycle; Cell Line, Tumor; Dacarbazine; Drug Screening Assays, Antitumor; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Membrane Potential, Mitochondrial; Mitosis; Molecular Structure; Molecular Targeted Therapy; Necrosis; Neoplasm Proteins; Reactive Oxygen Species; Tacrine; Temozolomide | 2018 |
Lycopene modulates growth and survival associated genes in prostate cancer.
Topics: Antineoplastic Agents; Apoptosis; Biomarkers, Tumor; Carotenoids; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dacarbazine; Humans; Lycopene; Male; Necrosis; PPAR gamma; Prostatic Neoplasms; Temozolomide | 2013 |
Artesunate enhances the antiproliferative effect of temozolomide on U87MG and A172 glioblastoma cell lines.
Topics: Antineoplastic Agents; Apoptosis; Artemisinins; Artesunate; Cell Line, Tumor; Cell Proliferation; Central Nervous System Neoplasms; Dacarbazine; Drug Synergism; Glioblastoma; Humans; Inhibitory Concentration 50; Necrosis; Temozolomide | 2014 |
Fractionated radiotherapy is the main stimulus for the induction of cell death and of Hsp70 release of p53 mutated glioblastoma cell lines.
Topics: Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Cycle; Cell Death; Cell Line, Tumor; Dacarbazine; Dose Fractionation, Radiation; G2 Phase; Glioblastoma; HMGB1 Protein; HSP70 Heat-Shock Proteins; Humans; Mutation; Necrosis; Temozolomide; Tumor Suppressor Protein p53; Valproic Acid | 2014 |
Early clinical and neuroradiological worsening after radiotherapy and concomitant temozolomide in patients with glioblastoma: tumour progression or radionecrosis?
Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Ataxia; Brain Neoplasms; Chemotherapy, Adjuvant; Confusion; Dacarbazine; Diagnosis, Differential; Female; Follow-Up Studies; Glioblastoma; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Necrosis; Neoplasm Recurrence, Local; Radiation Injuries; Radiation Tolerance; Radiotherapy, Adjuvant; Reoperation; Temozolomide; Treatment Outcome | 2009 |
Temozolomide- and fotemustine-induced apoptosis in human malignant melanoma cells: response related to MGMT, MMR, DSBs, and p53.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Caspases; Collagen Type XI; Dacarbazine; DNA Breaks, Double-Stranded; DNA Mismatch Repair; DNA Modification Methylases; DNA Repair Enzymes; Enzyme Activation; Everolimus; Humans; Melanoma; Necrosis; Phosphorylation; Sirolimus; Temozolomide; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Tumor Suppressor Proteins | 2009 |
Radiation induced early necrosis in patients with malignant gliomas receiving temozolomide.
Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease-Free Survival; Female; Glioma; Humans; Kaplan-Meier Estimate; Magnetic Resonance Spectroscopy; Male; Middle Aged; Necrosis; Radiation Injuries; Radiotherapy; Retrospective Studies; Temozolomide; Young Adult | 2010 |
Nijmegen breakage syndrome protein (NBN) causes resistance to methylating anticancer drugs such as temozolomide.
Topics: Antineoplastic Agents, Alkylating; Apoptosis; Caspase 7; Cell Cycle Proteins; Cell Line, Transformed; Cell Line, Tumor; Dacarbazine; DNA Methylation; Drug Resistance, Neoplasm; Fibroblasts; Guanine; Homozygote; Humans; Melanoma; Methylnitronitrosoguanidine; Mutagens; Mutation; Necrosis; Nijmegen Breakage Syndrome; Nuclear Proteins; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Temozolomide; Uveal Neoplasms | 2010 |
Favorable prognosis in patients with high-grade glioma with radiation necrosis: the University of Colorado reoperation series.
Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Carmustine; Colorado; Combined Modality Therapy; Dacarbazine; Female; Glioblastoma; Humans; Linear Models; Male; Middle Aged; Necrosis; Neoplasm Recurrence, Local; Proportional Hazards Models; Radiotherapy Dosage; Reoperation; Retreatment; Salvage Therapy; Temozolomide; Time Factors; Young Adult | 2011 |
Kinetic studies of the effects of Temodal and quercetin on astrocytoma cells.
Topics: Antineoplastic Agents, Alkylating; Antioxidants; Apoptosis; Astrocytoma; Autophagy; Cell Line, Tumor; Dacarbazine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Synergism; Humans; Necrosis; Quercetin; Temozolomide | 2011 |
Radiation necrosis of a high-grade glioma.
Topics: Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Dacarbazine; Glioma; Humans; Magnetic Resonance Angiography; Male; Middle Aged; Necrosis; Paclitaxel; Polyglutamic Acid; Temozolomide | 2012 |
Malignant glioma with angiocentric features.
Topics: Adolescent; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Glioma; Humans; Magnetic Resonance Imaging; Male; Necrosis; Neoplasm Recurrence, Local; Nervous System Diseases; Temozolomide | 2013 |
Bleomycin-induced Raynaud's phenomenon after single-dose exposure: risk factors and treatment with intravenous iloprost infusion.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Dacarbazine; Doxorubicin; Fingers; Hodgkin Disease; Humans; Iloprost; Infusions, Intravenous; Male; Middle Aged; Multimodal Imaging; Necrosis; Positron-Emission Tomography; Raynaud Disease; Remission Induction; Risk Factors; Tomography, X-Ray Computed; Treatment Outcome; Vasodilator Agents; Vinblastine | 2013 |
Induction of apoptosis and/or necrosis following exposure to antitumour agents in a melanoma cell line, probably through modulation of Bcl-2 family proteins.
Topics: Annexin A5; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Western; Caspase 3; Caspases; Cell Death; Cell Line, Tumor; Cell Survival; Cisplatin; Coloring Agents; Dacarbazine; Dactinomycin; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Activation; Flow Cytometry; Fluorescent Dyes; Humans; Melanoma; Necrosis; Proto-Oncogene Proteins c-bcl-2; Time Factors; Trypan Blue; Up-Regulation | 2003 |
In vitro antitumour activity of resveratrol in human melanoma cells sensitive or resistant to temozolomide.
Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Dacarbazine; Drug Resistance, Neoplasm; Humans; Inhibitory Concentration 50; Keratinocytes; Melanoma; Necrosis; Poly(ADP-ribose) Polymerases; Resveratrol; S Phase; Stilbenes; Temozolomide; Time Factors | 2004 |
Simulating chemotherapeutic schemes in the individualized treatment context: the paradigm of glioblastoma multiforme treated by temozolomide in vivo.
Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Cycle; Cell Division; Computer Graphics; Computer Simulation; Dacarbazine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Computer-Assisted; Glioblastoma; Humans; Image Processing, Computer-Assisted; Imaging, Three-Dimensional; Magnetic Resonance Imaging; Necrosis; Oligonucleotide Array Sequence Analysis; Software; Temozolomide | 2006 |
MGMT promoter methylation status can predict the incidence and outcome of pseudoprogression after concomitant radiochemotherapy in newly diagnosed glioblastoma patients.
Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Diseases; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease Progression; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Genetic Predisposition to Disease; Glioblastoma; Humans; Kaplan-Meier Estimate; Magnetic Resonance Imaging; Male; Middle Aged; Necrosis; Patient Selection; Promoter Regions, Genetic; Proportional Hazards Models; Radiation Injuries; Radiotherapy, Adjuvant; Retrospective Studies; Temozolomide; Time Factors; Treatment Outcome; Tumor Suppressor Proteins | 2008 |
Predictive testing with the subrenal capsule assay.
Topics: Altretamine; Animals; Antineoplastic Agents; Cyclophosphamide; Dacarbazine; Drug Evaluation, Preclinical; Drug Resistance; Humans; Kidney; Mice; Necrosis; Neoplasm Transplantation; Neoplasms; Prospective Studies; Transplantation, Heterologous | 1984 |
Veno-occlusive liver disease after dacarbazine therapy (DTIC) for melanoma.
Topics: Budd-Chiari Syndrome; Dacarbazine; Hepatic Veins; Humans; Male; Melanoma; Middle Aged; Necrosis | 1984 |
Acute liver dystrophy with thrombosis of hepatic veins: a fatal complication of dacarbazine treatment.
Topics: Chemical and Drug Induced Liver Injury; Dacarbazine; Female; Hepatic Veins; Humans; Liver Diseases; Male; Melanoma; Middle Aged; Necrosis; Skin Neoplasms; Thrombosis | 1983 |
Hepatic veno-occlusive disease due to DTIC.
Topics: Budd-Chiari Syndrome; Chemical and Drug Induced Liver Injury; Dacarbazine; Humans; Liver; Male; Melanoma; Middle Aged; Necrosis | 1980 |
Necrosis in melanoma metastases with treatment.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Dacarbazine; Disease-Free Survival; Follow-Up Studies; Humans; Lymph Node Excision; Male; Melanoma; Middle Aged; Necrosis; Skin Neoplasms; Time Factors; Tomography, X-Ray Computed; Treatment Outcome | 2001 |
Fatal necrosis of the liver during ABVD chemotherapy for Hodgkin's disease. A case report.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Budd-Chiari Syndrome; Dacarbazine; Doxorubicin; Hodgkin Disease; Humans; Liver; Male; Middle Aged; Necrosis; Vinblastine; Vincristine | 1986 |
Fatal hepatic vascular toxicity of DTIC. Is it really a rare event?
Topics: Aged; Budd-Chiari Syndrome; Combined Modality Therapy; Dacarbazine; Eosinophilia; Fever; Humans; Male; Melanoma; Middle Aged; Necrosis; Skin Neoplasms | 1988 |