dacarbazine and Invasiveness, Neoplasm

dacarbazine has been researched along with Invasiveness, Neoplasm in 97 studies

Research

Studies (97)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (2.06)	18.7374
1990's	4 (4.12)	18.2507
2000's	25 (25.77)	29.6817
2010's	66 (68.04)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Roth, P; Silginer, M; Stupp, R; Weller, M	1
Assié, G; Batisse-Lignier, M; Bonnet, F; Borot, S; Bourcigaux, N; Bresson, D; Caron, P; Castinetti, F; Chabre, O; Chanson, P; Cloix, L; Cortet, C; Delemer, B; Desailloud, R; Gaillard, S; Garcia, C; Haissaguerre, M; Jouanneau, E; Jublanc, C; Lasolle, H; Lebrun-Frenay, C; Raverot, G; Reznik, Y; Sadoul, JL; Taillandier, L; Vasiljevic, A; Villa, C	1
Fan, X; Lan, T; Qu, Y; Song, Y; Wang, H; Yu, C; Zhan, Q; Zhang, M; Zhang, Z; Zhao, Z	1
Chen, Y; Gao, F; Hou, J; Jiang, R; Kang, L; Li, Y; Liu, H; Liu, X; Yang, M; Yi, Y	1
Herrera-Rios, D; Hoerbelt, T; Jiang, T; Kahlert, UD; Koch, K; Li, G; Maciaczyk, D; Maciaczyk, J; Marquardt, V; Ouwens, DM; Pauck, D; Picard, D; Remke, M; Steiger, HJ; Zhang, W; Zhao, L	1
Hou, Y; Su, J; Wang, L; Wang, Z; Xia, J; Yan, J; Yin, X; Zhao, Z; Zheng, N; Zhou, X	1
Burman, P; Dekkers, OM; McCormack, A; Petersenn, S; Popovic, V; Raverot, G; Trouillas, J	1
Cui, Y; Feng, H; He, H; Ji, A; Li, J; Li, S; Lin, J; Lu, Y; Qiu, G; Song, C; Zou, Y	1
Chen, TC; Cho, HY; Hofman, FM; Marín-Ramos, NI; Schönthal, AH; Swenson, SD; Thein, TZ; Wang, W	1
Bähr, O; Belka, C; Braun, C; Gerlach, R; Glas, M; Goldbrunner, R; Hänel, M; Hattingen, E; Hau, P; Herrlinger, U; Junold, N; Kebir, S; Kortmann, RD; Krex, D; Mack, F; Niessen, M; Proescholdt, M; Rohde, V; Sabel, M; Schäfer, N; Schaub, C; Schlegel, U; Schmidt-Graf, F; Steinbach, JP; Stuplich, M; Tzaridis, T; Vatter, H; Weyerbrock, A	1
Chen, TC; Fayngor, RA; Hofman, FM; Jhaveri, N; Marín-Ramos, NI; Thein, TZ	1
Li, X; Liu, J; Wang, T; Yang, S; You, C	1
Bao, X; Cai, F; Dai, C; Deng, K; Feng, M; Guo, K; Jiao, Y; Junji, W; Lian, W; Liu, X; Ma, S; Wang, R; Wei, Z; Xing, B; Yang, Y; Yao, Y; Zhang, B	1
Cao, B; Dhruv, H; Eschbacher, JM; Kloss, J; Loftus, JC; Ross, JT; Schumacher, CA; Tran, NL; Tuncali, S; Williams, BO; Yang, Z	1
Brabletz, S; Brabletz, T; Deleyrolle, LP; Devers, KG; Kladde, MP; Kupper, MD; Nabilsi, NH; Neal, D; Reynolds, BA; Sarkisian, MR; Siebzehnrubl, D; Siebzehnrubl, FA; Silver, DJ; Steindler, DA; Suslov, O; Tugertimur, B; Yachnis, AT	1
Shi, L; Sun, G; Wan, Y; Wang, Z; Zhang, S	1
Asano, K; Ito, E; Katayama, K; Komori, T; Ohkuma, H; Sasaki, S; Sato, T; Terui, K	1
Allen, JE; Berg, A; Cheng, Y; Connor, J; El-Deiry, WS; Huang, SY; Liu, CG; Liu, X; Lu, Z; Ren, X; Webb, BS; Yang, JM; Yang, W; Yuan, Y; Zhang, L; Zhang, Y	1
Akiyama, Y; Asai, A; Ashizawa, T; Hayashi, N; Iizuka, A; Komiyama, M; Kume, A; Mitsuya, K; Miyata, H; Nakasu, Y; Omiya, M; Sugino, T; Yamaguchi, K	1
Cusimano, MD; Di Ieva, A; Kovacs, K; Rotondo, F; Syro, LV	1
Akiyama, Y; Ashizawa, T; Hayashi, N; Iizuka, A; Komiyama, M; Kume, A; Mitsuya, K; Miyata, H; Nakasu, Y; Omiya, M; Oshita, C; Sugino, T; Yamaguchi, K	1
Chen, Q; Jiang, BH; Jiang, C; Jiang, T; Kang, C; Li, C; Li, H; Liu, LZ; Liu, N; Liu, X; Qian, X; Shi, Z; Wang, L; Wang, X; You, Y	1
Han, S; Li, Z; Master, LM; Master, ZW; Wu, A	1
Adamska, K; Aldape, KD; Brandes, AA; Erridge, SC; Gorlia, T; Grujicic, D; Gupta, T; Hau, P; Hegi, ME; Herrlinger, U; Hicking, C; Hong, YK; Kim, CY; Kortmann, RD; Lhermitte, B; Markivskyy, A; McBain, C; Nabors, LB; Nam, DH; Perry, J; Picard, M; Pietsch, T; Rao, N; Reardon, DA; Schnell, O; Shen, CC; Steinbach, JP; Stupp, R; Taphoorn, MJ; Tarnawski, R; Thurzo, L; Tonn, JC; van den Bent, MJ; Weller, M; Weyerbrock, A; Wick, W; Wiegel, T	1
Bekar, A; Bilir, A; Budak, F; Cecener, G; Demir, C; Egeli, U; Erkan, LG; Evrensel, T; Guvenc, G; Malyer, H; Sahin, S; Taskapilioglu, MO; Tezcan, G; Tunca, B; Yalcin, M; Yilmaz, G	1
Cheng, Z; Gao, Z; Guo, H; Shen, X; Wu, L; Xiong, Y; Yang, L; Zhang, Y; Zhu, X	1
Cai, J; Chang, L; Chen, L; Cui, Y; Dou, Z; Du, W; Jiang, C; Liu, X; Liu, Y; Wang, G; Wang, H; Wang, X; Yi, L; Zhang, P	1
Guo, H; Guo, M; Wang, Y; Yang, L	1
Chen, S; Cheng, Y; Deng, J; Liang, P; Wang, F; Xie, Z; Xu, Z; Zhai, X; Zhang, Q; Zhao, H	1
Bendszus, M; Blaes, J; Heiland, S; Hertenstein, A; Jestaedt, L; Kessler, T; Milford, D; Osswald, M; Pfenning, PN; Platten, M; Rübmann, P; Ruiz de Almodóvar, C; Sahm, F; Urban, S; von Deimling, A; Weiler, M; Wick, A; Wick, W; Winkler, F	1
Amirbaigloo, A; Cusimano, MD; Di Ieva, A; Fathalla, H; Ghazi, AA; Kovacs, K; Rotondo, F; Syro, LV	1
Bartsch, JW; Biniossek, ML; Carl, B; Conrad, C; Culmsee, C; Dolga, AM; Dong, F; Eibach, M; Koller, G; Nimsky, C; Schieber, S; Schilling, O; Schlomann, U; Strik, H	1
Cao, Y; Guo, A; Jiao, Y; Li, H; Li, Y; Liu, Y; Qu, X; Wang, S; Xu, X; Zhao, J	1
Fei, X; Shi, L; Wang, Z; You, Y	1
Gao, D; He, J; Li, N; Liu, C; Wang, B; Zuo, G	1
Chen, CM; Huang, LJ; Kuo, SC; Lin, CL; Lin, CT; Syu, JP; Way, TD	1
Aller, J; Campderá, M; Estrada, J; Lilienfeld, H; Magallón, R; Martín, P; Palacios, N; Saucedo, G	1
Liang, P; Tang, H; Zhang, L; Zhao, J; Zhuang, Y	1
Agasse, F; Armstrong, D; Chen, L; Chen, TC; Commins, D; Hofman, FM; Jhaveri, N; Peng, L; Rosenstein-Sisson, R; Santiago, SV; Santos, T; Schönthal, AH; Vaikari, VP; Wang, W	1
Alizadeh, D; Badie, B; Berlin, JM; Chen, X; Da Fonseca, A; Gao, H; Guo, Q; Manuel, ER; Ouyang, M; Ren, H; Shah, S; Vonderfecht, SL; Weng, Y; White, EE; Yanyan, S; Zhang, I; Zhang, L	1
Chen, Y; Cheng, Y; Gao, H; Gao, J; Huang, H; Lei, T; Li, G; Li, P; Liu, P; Mu, Q; Sayari, AJ; Sun, Y; Yu, F; Zhai, X	1
Huang, GH; Li, N; Lv, SQ; Ma, ZX; Sidlauskas, K; Tang, JH; Xiang, Y; Xu, QF; Zhang, EE	1
Hu, Q; Li, S; Liu, Y; Yan, W; You, Y; Zeng, A	1
Fan, X; Lan, T; Qu, Y; Song, Y; Wang, H; Yu, C; Zhan, Q; Zhang, M; Zhang, Z; Zhao, Z; Zhou, W	1
Castro, MG; Doherty, R; Lowenstein, PR; Wilson, TJ; Zamler, DB	1
Chang, JH; Cheong, JH; Choi, J; Huh, YM; Jeon, JY; Kang, SG; Kim, EH; Kim, P; Kim, SH; Koh, I; Lee, JH; Lee, SJ; Park, J; Pollak, M; Shim, JK; Yook, JI; Yun, M	1
Boop, FA; Cai, C; Cheng, J; He, P; Pfeffer, LM; Pfeffer, SR; Sims, M; Wang, Y; Yang, CH; Yue, J	1
Cisneros Castillo, LR; Oancea, AD; Régnier-Vigouroux, A; Stüllein, C	1
Kim, DH; Li, S; Liu, Y; Lu, G; Xue, H; Yang, SH; Zhu, JJ	1
Chen, J; Li, C; Tan, Q; Wang, M; Wang, Y; Xie, C; Zhan, W; Zhang, Z	1
Bao, X; Dai, C; Deng, K; Feng, M; Lian, W; Liu, X; Ma, S; Ma, W; Sun, B; Wang, R; Wang, Y; Xing, B; Yao, Y; Zhong, D	1
Di, H; Du, J; Sun, S; Wang, J; Wang, Q; Wang, X; Xu, B; Xu, X	1
Guo, H; Liu, H; Liu, J; Liu, T; Shi, F; Wu, L; Wu, Q; Zhang, Q; Zhang, R	1
Kudriavtsev, DV; Kudriavtseva, GT; Mardynskiĭ, IuS	1
Anile, C; Balducci, M; de Bonis, P; Lama, G; Lauriola, L; Maira, G; Mangiola, A; Sica, G	1
Clynes, M; Crown, J; Eustace, AJ; O'Donovan, N	1
Ang, BT; Chong, KH; Chua, C; See, SJ; Tang, C; Wong, MC; Zaiden, N	1
Campos, M; Flaherty, KT; Garbe, C; Gogel, J; Kulms, D; Lasithiotakis, K; Maczey, E; Meier, F; Niessner, H; Schittek, B; Sinnberg, T	1
Chaskis, C; De Ridder, M; Everaert, H; Michotte, A; Neyns, B	1
Lefranc, F	1
Adams, B; Maurer, GD; Stupp, R; Tabatabai, G; Tritschler, I; Weller, M; Wick, W	1
Chang, PN; Lee, DT; Ling, MT; Wong, YC; Yap, WN; Yap, YL	1
Campion, L; Cartron, PF; Charbord, J; Debien, E; Hervouet, E; Menanteau, J; Vallette, FM	1
Howson-Jan, K; Hsia, CC; Rizkalla, KS	1
Bleyer, A; Choi, M; Fuller, CD; Raney, RB; Wang, SJ	1
Bruce, JN; Fine, RL; Freda, PU; Isaacson, SR; Lee, Y; Thearle, MS	1
Benito, M; Mintzer, DM; Nagamine, M; Newman, J; Zheng, S	1
Bontempi, G; Bruyère, C; Decaestecker, C; Dubois, J; Haibe-Kains, B; Kiss, R; Lamoral-Theys, D; Le Calvé, B; Le Mercier, M; Lefranc, F; Rynkowski, MA	1
Agha, CA; Elias, DA; Fathallah-Shaykh, HM; Hassan, A; Ibrahim, S	1
Bendinelli, S; Casalini, F; Costa, B; Da Pozzo, E; Da Settimo, F; Gabelloni, P; Martini, C; Nuti, E; Orlandini, E; Rossello, A	1
Assaker, R; Bernier, M; Borson-Chazot, F; Brue, T; Caron, P; Chabre, O; Chanson, P; Cornélius, A; Cortet-Rudelli, C; de Fraipont, F; Dufour, H; Figarella-Branger, D; François, P; Gaillard, S; Jouanneau, E; Muller, M; Passagia, JG; Raverot, G; Salenave, S; Sturm, N; Trouillas, J	1
Aghi, MK; Oh, MC	1
Amaravadi, RK; Li, LZ; Lum, JJ; Ma, XH; McAfee, QW; Nathanson, KL; Piao, S; Wang, D	1
Caminal, JM; Fabra, A; Ferreres, JR; Marcoval, J; Penín, RM; Piulats, JM	1
Akiyama, S; Fukushige, T; Gunshin, K; Ikeda, R; Kanekura, T; Kawai, K; Matsushita, S; Okumura, H; Tajitsu, Y; Takeda, Y; Ushiyama, M; Yamada, K	1
Chen, TC; Cho, HY; Goldkorn, A; Hofman, FM; Jhaveri, N; Lee, DJ; Leong, MN; Louie, SG; Petasis, NA; Schönthal, AH; Torres, S; Tseng, J; Wang, W; Xu, T	1
Matsuo, H; Nagatani, K; Nakanishi, K; Nawashiro, H; Osada, H; Otani, N; Shimazaki, H; Shinomiya, N; Takeuchi, S; Toyooka, T; Uozumi, Y; Wada, K	1
Chen, J; Hu, G; Lu, Y; Luo, C; Qian, J; Wang, J; Wang, Q	1
Arnold, H; Damasceno, R; Günther, W; Pawlak, E; Terzis, AJ	1
Crump, M; Gospodarowicz, MK; Hodgson, DC; Pintilie, M; Sun, A; Tsang, RW; Wells, W	1
Inoue, H; Kunisada, T; Morimoto, Y; Ohata, N; Ozaki, T; Tanaka, M	1
Alper, F; Eroğlu, A; Gündoğdu, C; Karaoğlanoğlu, N; Kürkçüoğlu, IC	1
Chamberlain, MC	1
Nakada, M	1
Kiss, R; Mathieu, V; Mijatovic, T; van Damme, M	1
Amatruda, TT; Elashoff, RM; Gonzalez, R; Hoon, DS; Koyanagi, K; Lewis, K; O'Day, SJ; Robinson, WA; Takeuchi, H; Umetani, N; Wang, HJ	1
Breipohl, W; Fountoulakis, M; Friedlein, A; Golubnitschaja, O; Haertel, N; Leppert, D; Moenkemann, H; Schild, H; Schueller, H; Trog, D; Yeghiazaryan, K	1
Beijnen, JH; Boogerd, W; Buckle, T; Heerschap, A; Kemper, EM; Küsters, B; Leenders, W; Lyons, S; van Tellingen, O	1
Hambardzumyan, D; Holland, EC; Kreger, AR; Leopold, WR; McConville, P; Moody, JB; Rehemtulla, A; Ross, BD; Woolliscroft, MJ	1
Kiss, R; Lefranc, F; Mijatovic, T	1
Bui, NB; Coindre, JM; Kantor, G; Kind, M; Stöckle, E; Thomas, L	1
Dahut, WL; Lynch, JH; Mordkin, RM	1
Dichgans, J; Rodemann, HP; Schulz, JB; Weller, M; Wick, A; Wick, W	1
Nagel, GA; Rufli, T	1
Baker, AR; Barth, RJ; Venzon, DJ	1
Kretschmar, CS; Linggood, RM	1
Cangir, A; Goepfert, H; Lee, YY	1

Reviews

7 review(s) available for dacarbazine and Invasiveness, Neoplasm

Article	Year
Aggressive pituitary adenomas--diagnosis and emerging treatments. Nature reviews. Endocrinology, 2014, Volume: 10, Issue:7 Topics: Adenoma; Biomarkers, Tumor; Dacarbazine; Humans; Ki-67 Antigen; Neoplasm Invasiveness; Neovascularization, Pathologic; Pituitary Neoplasms; Temozolomide; Tumor Suppressor Protein p53	2014
Treatment of invasive silent somatotroph pituitary adenoma with temozolomide. Report of a case and review of the literature. Endocrine pathology, 2015, Volume: 26, Issue:2 Topics: Adenoma; Adult; Antineoplastic Agents, Alkylating; Asymptomatic Diseases; Dacarbazine; Growth Hormone-Secreting Pituitary Adenoma; Humans; Male; Neoplasm Invasiveness; Temozolomide	2015
Dopamine agonist-resistant prolactinomas. Journal of neurosurgery, 2011, Volume: 114, Issue:5 Topics: Antineoplastic Agents, Alkylating; Cell Division; Dacarbazine; Dopamine Agonists; Drug Resistance, Neoplasm; Female; Humans; Male; Mitotic Index; Neoplasm Invasiveness; Pituitary Neoplasms; Prolactin; Prolactinoma; Receptors, Estrogen; Sex Factors; Temozolomide	2011
[Role of extracellular matrix degradation enzyme for glioma invasion]. Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63 Suppl 9 Topics: ADAM Proteins; Brain Neoplasms; Dacarbazine; Drug Design; Enzyme Inhibitors; Extracellular Matrix; Glioma; Humans; Hydroxamic Acids; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Neoplasm Invasiveness; Serine Endopeptidases; Temozolomide; Tetracyclines	2005
[Locally developed sarcoma of the thoracic wall]. Bulletin du cancer, 1996, Volume: 83, Issue:5 Topics: Antineoplastic Combined Chemotherapy Protocols; Back; Chemotherapy, Adjuvant; Combined Modality Therapy; Dacarbazine; Doxorubicin; Humans; Ifosfamide; Magnetic Resonance Imaging; Male; Mesna; Middle Aged; Neoplasm Invasiveness; Prognosis; Radiotherapy Dosage; Sarcoma; Soft Tissue Neoplasms; Thoracic Neoplasms	1996
Renal angiosarcoma: a rare primary genitourinary malignancy. Southern medical journal, 1997, Volume: 90, Issue:11 Topics: Aged; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Dacarbazine; Doxorubicin; Hemangiosarcoma; Humans; Kidney Neoplasms; Male; Mouth Neoplasms; Neoplasm Invasiveness; Omentum; Peritoneal Neoplasms; Prognosis; Splenic Neoplasms	1997
Chemotherapeutic treatment of extensive optic pathway tumors in infants. Journal of neuro-oncology, 1991, Volume: 10, Issue:3 Topics: Antineoplastic Combined Chemotherapy Protocols; Ascites; Astrocytoma; Cerebrospinal Fluid Shunts; Cisplatin; Cranial Nerve Neoplasms; Cyclophosphamide; Dacarbazine; Doxorubicin; Dwarfism, Pituitary; Female; Humans; Hydrocephalus; Infant; Male; Mechlorethamine; Neoplasm Invasiveness; Optic Chiasm; Optic Nerve Diseases; Peritoneal Neoplasms; Vincristine; Vision Disorders	1991

Trials

3 trial(s) available for dacarbazine and Invasiveness, Neoplasm

Article	Year
Tumor growth patterns of MGMT-non-methylated glioblastoma in the randomized GLARIUS trial. Journal of cancer research and clinical oncology, 2018, Volume: 144, Issue:8 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Cell Growth Processes; Dacarbazine; DNA Modification Methylases; DNA Repair Enzymes; Female; Glioblastoma; Humans; Irinotecan; Magnetic Resonance Imaging; Male; Methylation; Middle Aged; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Radiotherapy; Temozolomide; Tumor Suppressor Proteins	2018
Cilengitide combined with standard treatment for patients with newly diagnosed glioblastoma with methylated MGMT promoter (CENTRIC EORTC 26071-22072 study): a multicentre, randomised, open-label, phase 3 trial. The Lancet. Oncology, 2014, Volume: 15, Issue:10 Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Confidence Intervals; Dacarbazine; Disease-Free Survival; DNA Modification Methylases; DNA Repair Enzymes; Dose-Response Relationship, Drug; Drug Administration Schedule; Early Detection of Cancer; Female; Follow-Up Studies; Glioblastoma; Humans; Kaplan-Meier Estimate; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Patient Selection; Promoter Regions, Genetic; Proportional Hazards Models; Reference Values; Snake Venoms; Survival Analysis; Temozolomide; Treatment Outcome; Tumor Suppressor Proteins	2014
Invasive tumor cells and prognosis in a selected population of patients with glioblastoma multiforme. Cancer, 2008, Aug-15, Volume: 113, Issue:4 Topics: Aged; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Female; Glioblastoma; Humans; Male; Middle Aged; Neoplasm Invasiveness; Prognosis; Survival Analysis; Temozolomide; Treatment Outcome	2008

Other Studies

87 other study(ies) available for dacarbazine and Invasiveness, Neoplasm

Article	Year
Biological activity of tumor-treating fields in preclinical glioma models. Cell death & disease, 2017, 04-20, Volume: 8, Issue:4 Topics: Apoptosis; Brain Neoplasms; Caspases; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Survival; Dacarbazine; DNA Modification Methylases; DNA Repair Enzymes; Glioma; Humans; Neoplasm Invasiveness; Temozolomide; Tumor Suppressor Proteins	2017
Temozolomide treatment can improve overall survival in aggressive pituitary tumors and pituitary carcinomas. European journal of endocrinology, 2017, Volume: 176, Issue:6 Topics: ACTH-Secreting Pituitary Adenoma; Adult; Antineoplastic Agents, Alkylating; Carcinoma; Chemoradiotherapy; Cohort Studies; Dacarbazine; Drug Resistance, Neoplasm; Female; Follow-Up Studies; France; Humans; Male; Neoplasm Grading; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Pituitary Neoplasms; Practice Patterns, Physicians'; Prolactinoma; Retrospective Studies; Survival Analysis; Temozolomide; Tumor Burden	2017
Downregulation of β-arrestin 1 suppresses glioblastoma cell malignant progression vis inhibition of Src signaling. Experimental cell research, 2017, 08-01, Volume: 357, Issue:1 Topics: Animals; beta-Arrestin 1; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Dacarbazine; Disease Progression; Down-Regulation; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Mice; Neoplasm Invasiveness; Proto-Oncogene Proteins pp60(c-src); Signal Transduction; Temozolomide	2017
Down-Regulation of AQP4 Expression via p38 MAPK Signaling in Temozolomide-Induced Glioma Cells Growth Inhibition and Invasion Impairment. Journal of cellular biochemistry, 2017, Volume: 118, Issue:12 Topics: Aquaporin 4; Cell Line, Tumor; Dacarbazine; Down-Regulation; Gene Expression Regulation, Neoplastic; Glioma; Humans; MAP Kinase Signaling System; Neoplasm Invasiveness; Neoplasm Proteins; p38 Mitogen-Activated Protein Kinases; Temozolomide	2017
CBF1 is clinically prognostic and serves as a target to block cellular invasion and chemoresistance of EMT-like glioblastoma cells. British journal of cancer, 2017, Jun-27, Volume: 117, Issue:1 Topics: Antineoplastic Agents, Alkylating; Blotting, Western; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Computer Simulation; Dacarbazine; Databases, Factual; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; Glioblastoma; Glycolysis; Humans; Immunoglobulin J Recombination Signal Sequence-Binding Protein; Isocitrate Dehydrogenase; Mutation; Neoplasm Invasiveness; Neoplastic Stem Cells; Prognosis; RNA, Messenger; Temozolomide; Tumor Hypoxia; Zinc Finger E-box-Binding Homeobox 1	2017
MiR-26b reverses temozolomide resistance via targeting Wee1 in glioma cells. Cell cycle (Georgetown, Tex.), 2017, Oct-18, Volume: 16, Issue:20 Topics: Base Sequence; Biomarkers, Tumor; Cell Cycle Proteins; Cell Line, Tumor; Cell Movement; Dacarbazine; Down-Regulation; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; Glioma; Humans; MicroRNAs; Neoplasm Invasiveness; Nuclear Proteins; Phenotype; Protein-Tyrosine Kinases; Temozolomide	2017
Treatment of aggressive pituitary tumours and carcinomas: results of a European Society of Endocrinology (ESE) survey 2016. European journal of endocrinology, 2018, Volume: 178, Issue:3 Topics: Adenoma; Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; Carcinoma; Carmustine; Child; Child, Preschool; Cranial Irradiation; Dacarbazine; DNA Modification Methylases; DNA Repair Enzymes; Endocrinology; Europe; Female; Humans; Ki-67 Antigen; Male; Middle Aged; Neoplasm Invasiveness; Neurosurgical Procedures; Pituitary Neoplasms; Societies, Medical; Surveys and Questionnaires; Temozolomide; Thalidomide; Tumor Suppressor Proteins; Young Adult	2018
FBW7 is associated with prognosis, inhibits malignancies and enhances temozolomide sensitivity in glioblastoma cells. Cancer science, 2018, Volume: 109, Issue:4 Topics: Apoptosis; Aurora Kinase B; Cell Count; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dacarbazine; Down-Regulation; F-Box-WD Repeat-Containing Protein 7; Flow Cytometry; G2 Phase Cell Cycle Checkpoints; Glioblastoma; Glioma; Humans; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Invasiveness; Prognosis; Receptor, Notch1; RNA, Small Interfering; Temozolomide; Ubiquitin-Protein Ligases	2018
NEO212 Inhibits Migration and Invasion of Glioma Stem Cells. Molecular cancer therapeutics, 2018, Volume: 17, Issue:3 Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Dacarbazine; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glioma; Male; Mice, Inbred NOD; Mice, SCID; Neoplasm Invasiveness; Neoplastic Stem Cells; Survival Analysis; Tumor Cells, Cultured; Xenograft Model Antitumor Assays	2018
NEO212, a conjugate of temozolomide and perillyl alcohol, blocks the endothelial-to-mesenchymal transition in tumor-associated brain endothelial cells in glioblastoma. Cancer letters, 2019, 02-01, Volume: 442 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Coculture Techniques; Dacarbazine; Endothelial Cells; Epithelial-Mesenchymal Transition; Glioblastoma; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice, Nude; Neoplasm Invasiveness; Neovascularization, Pathologic; Receptors, Notch; Signal Transduction; Transforming Growth Factor beta; Xenograft Model Antitumor Assays	2019
Cerebellar glioblastoma multiforme: a retrospective study of 28 patients at a single institution. The International journal of neuroscience, 2013, Volume: 123, Issue:10 Topics: Adolescent; Adult; Age Factors; Aged; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Child; Dacarbazine; Disease-Free Survival; Female; Glioblastoma; Humans; Kaplan-Meier Estimate; Karnofsky Performance Status; Magnetic Resonance Imaging; Male; Middle Aged; Neoplasm Invasiveness; Neurosurgical Procedures; Prognosis; Radiosurgery; Retrospective Studies; Sex Factors; Survival Analysis; Temozolomide; Young Adult	2013
Pyrimethamine sensitizes pituitary adenomas cells to temozolomide through cathepsin B-dependent and caspase-dependent apoptotic pathways. International journal of cancer, 2013, Oct-15, Volume: 133, Issue:8 Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspase 7; Caspase 9; Cathepsin B; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cytochromes c; Dacarbazine; DNA Damage; Drug Synergism; Female; Folic Acid Antagonists; Histones; Leucovorin; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred NOD; Mice, SCID; Mitochondria; Neoplasm Invasiveness; Neoplasm Transplantation; Phosphorylation; Pituitary Neoplasms; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; Pyrimethamine; Rats; Temozolomide; Up-Regulation; Xenograft Model Antitumor Assays	2013
TROY (TNFRSF19) promotes glioblastoma survival signaling and therapeutic resistance. Molecular cancer research : MCR, 2013, Volume: 11, Issue:8 Topics: Animals; Antineoplastic Agents; Apoptosis; Astrocytes; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Chickens; Dacarbazine; Drug Resistance, Neoplasm; Epilepsy; Female; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Glioblastoma; Humans; Mice; Mice, Nude; Mice, Transgenic; Neoplasm Invasiveness; NF-kappa B; Proto-Oncogene Proteins c-akt; Receptors, Tumor Necrosis Factor; Signal Transduction; Temozolomide; Xenograft Model Antitumor Assays	2013
The ZEB1 pathway links glioblastoma initiation, invasion and chemoresistance. EMBO molecular medicine, 2013, Volume: 5, Issue:8 Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Dacarbazine; DNA Modification Methylases; DNA Repair Enzymes; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Glioblastoma; Homeodomain Proteins; Humans; Kruppel-Like Transcription Factors; Mice; Mice, SCID; Neoplasm Invasiveness; Neoplasm Transplantation; Nerve Tissue Proteins; Proto-Oncogene Proteins c-myb; Receptors, Immunologic; Roundabout Proteins; Temozolomide; Transcription Factors; Treatment Outcome; Tumor Suppressor Proteins; Zinc Finger E-box-Binding Homeobox 1	2013
MicroRNA-125b inhibitor sensitizes human primary glioblastoma cells to chemotherapeutic drug temozolomide on invasion. In vitro cellular & developmental biology. Animal, 2013, Volume: 49, Issue:8 Topics: Cell Line, Tumor; Dacarbazine; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; In Vitro Techniques; MicroRNAs; Neoplasm Invasiveness; Receptor, Notch1; Temozolomide	2013
Case of pediatric optic pathway oligodendroglioma presenting widespread invasion and dissemination in the cerebrospinal fluid. Brain tumor pathology, 2014, Volume: 31, Issue:3 Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Chemoradiotherapy, Adjuvant; Child; Dacarbazine; Female; Humans; Magnetic Resonance Imaging; Neoplasm Invasiveness; Neurosurgical Procedures; Oligodendroglioma; Optic Nerve Neoplasms; Temozolomide; Treatment Outcome; Vincristine; Visual Pathways	2014
The NFκB inhibitor, SN50, induces differentiation of glioma stem cells and suppresses their oncogenic phenotype. Cancer biology & therapy, 2014, Volume: 15, Issue:5 Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Differentiation; Dacarbazine; Drug Resistance, Neoplasm; Gene Expression Regulation; Glioblastoma; Heterografts; Humans; Mice, Nude; Neoplasm Invasiveness; Neoplastic Stem Cells; NF-kappa B; Peptides; Temozolomide; Tumor Cells, Cultured	2014
Effect of the STAT3 inhibitor STX-0119 on the proliferation of a temozolomide-resistant glioblastoma cell line. International journal of oncology, 2014, Volume: 45, Issue:1 Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Dacarbazine; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Male; Mice; Mice, Nude; Neoplasm Invasiveness; Neoplasms, Experimental; Oxadiazoles; Quinolines; STAT3 Transcription Factor; Temozolomide; Xenograft Model Antitumor Assays	2014
YKL-40 downregulation is a key factor to overcome temozolomide resistance in a glioblastoma cell line. Oncology reports, 2014, Volume: 32, Issue:1 Topics: Adipokines; Animals; Antigens, Neoplasm; Biomarkers, Tumor; Cell Line, Tumor; Chitinase-3-Like Protein 1; Dacarbazine; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Lectins; Male; Mice; Mice, Nude; Neoplasm Invasiveness; Neoplasm Proteins; Neoplasms, Experimental; Temozolomide; Xenograft Model Antitumor Assays	2014
MiR-124 governs glioma growth and angiogenesis and enhances chemosensitivity by targeting R-Ras and N-Ras. Neuro-oncology, 2014, Volume: 16, Issue:10 Topics: Animals; Apoptosis; Brain; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Dacarbazine; Genes, ras; Glioma; Humans; Male; Mice; Mice, Nude; MicroRNAs; Neoplasm Invasiveness; Neovascularization, Pathologic; ras Proteins; Signal Transduction; Temozolomide	2014
Exogenous IGFBP-2 promotes proliferation, invasion, and chemoresistance to temozolomide in glioma cells via the integrin β1-ERK pathway. British journal of cancer, 2014, Sep-23, Volume: 111, Issue:7 Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Dacarbazine; Drug Resistance, Neoplasm; Extracellular Signal-Regulated MAP Kinases; Gene Expression; Glioma; Humans; Insulin-Like Growth Factor Binding Protein 2; Integrin beta1; MAP Kinase Signaling System; Neoplasm Invasiveness; Temozolomide; Tissue Array Analysis	2014
Ficus carica latex prevents invasion through induction of let-7d expression in GBM cell lines. Cellular and molecular neurobiology, 2015, Volume: 35, Issue:2 Topics: Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chemical Fractionation; Dacarbazine; Ficus; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; In Situ Nick-End Labeling; Latex; MicroRNAs; Models, Biological; Neoplasm Invasiveness; Neovascularization, Physiologic; Phytotherapy; Plant Extracts; Temozolomide	2015
Annexin A5 promotes invasion and chemoresistance to temozolomide in glioblastoma multiforme cells. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2014, Volume: 35, Issue:12 Topics: Annexin A5; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cadherins; Cell Line, Tumor; Dacarbazine; Drug Resistance, Neoplasm; Gene Expression; Gene Knockdown Techniques; Glioblastoma; Humans; Matrix Metalloproteinase 2; Neoplasm Invasiveness; Phosphorylation; Proto-Oncogene Proteins c-akt; Snail Family Transcription Factors; Temozolomide; Transcription Factors; Twist-Related Protein 1	2014
Suppressor of fused (Sufu) represses Gli1 transcription and nuclear accumulation, inhibits glioma cell proliferation, invasion and vasculogenic mimicry, improving glioma chemo-sensitivity and prognosis. Oncotarget, 2014, Nov-30, Volume: 5, Issue:22 Topics: Adult; Animals; Brain Neoplasms; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Dacarbazine; Disease Progression; Down-Regulation; Female; Glioma; Humans; Male; Mice; Mice, Nude; Middle Aged; Neoplasm Invasiveness; Neoplasm Transplantation; Prognosis; Repressor Proteins; RNA, Small Interfering; Temozolomide; Transcription Factors; Treatment Outcome; Veratrum Alkaloids; Zinc Finger Protein GLI1	2014
Synergistic Anti-Cancer Effects of Icariin and Temozolomide in Glioblastoma. Cell biochemistry and biophysics, 2015, Volume: 71, Issue:3 Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dacarbazine; Drug Synergism; Flavonoids; Glioblastoma; Humans; Neoplasm Invasiveness; NF-kappa B; Signal Transduction; Temozolomide	2015
Effects of hnRNP A2/B1 Knockdown on Inhibition of Glioblastoma Cell Invasion, Growth and Survival. Molecular neurobiology, 2016, Volume: 53, Issue:2 Topics: Brain Neoplasms; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dacarbazine; Drug Resistance, Neoplasm; Female; Gene Knockdown Techniques; Glioblastoma; Heterogeneous-Nuclear Ribonucleoprotein Group A-B; Humans; Immunohistochemistry; Male; Matrix Metalloproteinases; Middle Aged; Neoplasm Invasiveness; STAT3 Transcription Factor; Temozolomide; Tumor Stem Cell Assay	2016
Glioma cell VEGFR-2 confers resistance to chemotherapeutic and antiangiogenic treatments in PTEN-deficient glioblastoma. Oncotarget, 2015, Oct-13, Volume: 6, Issue:31 Topics: Angiogenesis Inhibitors; Animals; Bevacizumab; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dacarbazine; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Glioma; Humans; Kaplan-Meier Estimate; Mice, Nude; Neoplasm Invasiveness; Neovascularization, Pathologic; PTEN Phosphohydrolase; Signal Transduction; Temozolomide; Time Factors; Transfection; Tumor Burden; Vascular Endothelial Growth Factor Receptor-2; Xenograft Model Antitumor Assays	2015
The metalloprotease-disintegrin ADAM8 contributes to temozolomide chemoresistance and enhanced invasiveness of human glioblastoma cells. Neuro-oncology, 2015, Volume: 17, Issue:11 Topics: ADAM Proteins; Antineoplastic Agents; Blotting, Western; Brain Neoplasms; Cell Separation; Cell Survival; Dacarbazine; Drug Resistance, Neoplasm; Enzyme-Linked Immunosorbent Assay; Fluorescence Resonance Energy Transfer; Glioblastoma; Humans; Immunoblotting; Membrane Proteins; Neoplasm Invasiveness; Real-Time Polymerase Chain Reaction; Temozolomide; Transcriptome	2015
Resveratrol Inhibits the Invasion of Glioblastoma-Initiating Cells via Down-Regulation of the PI3K/Akt/NF-κB Signaling Pathway. Nutrients, 2015, Jun-02, Volume: 7, Issue:6 Topics: Animals; Cell Adhesion; Cell Line, Tumor; Cell Survival; Dacarbazine; Down-Regulation; Glioblastoma; Humans; Male; Matrix Metalloproteinase 2; Mice; Mice, Inbred NOD; Mice, SCID; Neoplasm Invasiveness; Neoplasm Transplantation; NF-kappa B; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Resveratrol; Signal Transduction; Stilbenes; Temozolomide	2015
PI3K inhibitor combined with miR-125b inhibitor sensitize TMZ-induced anti-glioma stem cancer effects through inactivation of Wnt/β-catenin signaling pathway. In vitro cellular & developmental biology. Animal, 2015, Volume: 51, Issue:10 Topics: Antineoplastic Agents, Alkylating; Apoptosis; beta Catenin; Cell Movement; Cell Survival; Chromones; Dacarbazine; Drug Resistance, Neoplasm; Glioblastoma; Humans; MicroRNAs; Morpholines; Neoplasm Invasiveness; Neoplastic Stem Cells; Phosphoinositide-3 Kinase Inhibitors; Primary Cell Culture; Temozolomide; Tumor Cells, Cultured; Wnt Proteins; Wnt Signaling Pathway	2015
HMGN5 blockade by siRNA enhances apoptosis, suppresses invasion and increases chemosensitivity to temozolomide in meningiomas. International journal of oncology, 2015, Volume: 47, Issue:4 Topics: Aged; Antineoplastic Agents; Apoptosis; Blotting, Western; Dacarbazine; Drug Resistance, Neoplasm; Female; Gene Knockdown Techniques; HMGN Proteins; Humans; Immunohistochemistry; Kaplan-Meier Estimate; Male; Meningeal Neoplasms; Meningioma; Middle Aged; Neoplasm Invasiveness; Prognosis; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Temozolomide; Trans-Activators; Transfection	2015
BC3EE2,9B, a synthetic carbazole derivative, upregulates autophagy and synergistically sensitizes human GBM8901 glioblastoma cells to temozolomide. International journal of molecular medicine, 2015, Volume: 36, Issue:5 Topics: Antineoplastic Agents; Autophagy; Brain Neoplasms; Carbazoles; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dacarbazine; Drug Resistance, Neoplasm; Drug Synergism; G1 Phase; Glioblastoma; Humans; Neoplasm Invasiveness; Proto-Oncogene Proteins c-akt; Signal Transduction; Temozolomide; Up-Regulation	2015
Temozolomide for aggressive ACTH pituitary tumors: failure of a second course of treatment. Pituitary, 2016, Volume: 19, Issue:2 Topics: ACTH-Secreting Pituitary Adenoma; Adenoma; Adult; Antineoplastic Agents, Alkylating; Chemotherapy, Adjuvant; Dacarbazine; Disease Progression; Humans; Hydrocortisone; Male; Middle Aged; Neoplasm Invasiveness; Retrospective Studies; Temozolomide; Treatment Failure	2016
SRPX2 Enhances the Epithelial-Mesenchymal Transition and Temozolomide Resistance in Glioblastoma Cells. Cellular and molecular neurobiology, 2016, Volume: 36, Issue:7 Topics: Brain Neoplasms; Cell Line, Tumor; Cell Movement; Dacarbazine; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; Glioblastoma; Humans; Membrane Proteins; Neoplasm Invasiveness; Neoplasm Proteins; Nerve Tissue Proteins; Prognosis; RNA Interference; Temozolomide	2016
A novel drug conjugate, NEO212, targeting proneural and mesenchymal subtypes of patient-derived glioma cancer stem cells. Cancer letters, 2016, Feb-28, Volume: 371, Issue:2 Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Biomarkers, Tumor; Brain Neoplasms; Dacarbazine; DNA Breaks, Double-Stranded; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Glioma; Humans; Male; Mesenchymal Stem Cells; Mice, Inbred NOD; Mice, SCID; Neoplasm Invasiveness; Neoplastic Stem Cells; Neural Stem Cells; Temozolomide; Time Factors; Tumor Burden; Tumor Cells, Cultured; Xenograft Model Antitumor Assays	2016
Metronomic Doses of Temozolomide Enhance the Efficacy of Carbon Nanotube CpG Immunotherapy in an Invasive Glioma Model. PloS one, 2016, Volume: 11, Issue:2 Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Death; Cell Line, Tumor; Dacarbazine; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Glioma; Immunotherapy; Inflammation; Lipids; Mice, Inbred C57BL; Nanotubes, Carbon; Neoplasm Invasiveness; Oligodeoxyribonucleotides; Polyethylene Glycols; Spleen; Temozolomide; Treatment Outcome	2016
SPOCK1 is upregulated in recurrent glioblastoma and contributes to metastasis and Temozolomide resistance. Cell proliferation, 2016, Volume: 49, Issue:2 Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Dacarbazine; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; Glioblastoma; Humans; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Proteoglycans; Temozolomide	2016
Downregulation of HIF-1a sensitizes U251 glioma cells to the temozolomide (TMZ) treatment. Experimental cell research, 2016, 05-01, Volume: 343, Issue:2 Topics: Apoptosis; Brain Neoplasms; Cell Differentiation; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dacarbazine; Down-Regulation; Gene Expression Regulation, Neoplastic; Glioma; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Neoplasm Invasiveness; Neoplasm Proteins; RNA, Small Interfering; Signal Transduction; Temozolomide; Transfection	2016
miR-423-5p contributes to a malignant phenotype and temozolomide chemoresistance in glioblastomas. Neuro-oncology, 2017, Volume: 19, Issue:1 Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Cycle Proteins; Cell Proliferation; Dacarbazine; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Glioblastoma; Homeodomain Proteins; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; MicroRNAs; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neoplasm Invasiveness; Phenotype; Prognosis; Proto-Oncogene Proteins c-akt; Signal Transduction; Temozolomide; Tumor Cells, Cultured; Tumor Suppressor Proteins; Xenograft Model Antitumor Assays	2017
Targeting hyperactivated DNA-PKcs by KU0060648 inhibits glioma progression and enhances temozolomide therapy via suppression of AKT signaling. Oncotarget, 2016, Aug-23, Volume: 7, Issue:34 Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; DNA-Activated Protein Kinase; Drug Synergism; Female; Glioma; Humans; Mice; Neoplasm Invasiveness; Proto-Oncogene Proteins c-akt; Signal Transduction; Temozolomide; Xenograft Model Antitumor Assays	2016
Reversibility of glioma stem cells' phenotypes explains their complex in vitro and in vivo behavior: Discovery of a novel neurosphere-specific enzyme, cGMP-dependent protein kinase 1, using the genomic landscape of human glioma stem cells as a discovery t Oncotarget, 2016, 09-27, Volume: 7, Issue:39 Topics: Animals; Apoptosis; Biomarkers, Tumor; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Chemotaxis; Cyclic GMP-Dependent Protein Kinase Type I; Dacarbazine; Doxorubicin; Female; Glioblastoma; Glioma; Humans; Male; Mice; Mice, Transgenic; Neoplasm Invasiveness; Neoplastic Stem Cells; Neurons; Oligonucleotide Array Sequence Analysis; Paclitaxel; Phenotype; Stem Cells; Temozolomide	2016
Inhibiting stemness and invasive properties of glioblastoma tumorsphere by combined treatment with temozolomide and a newly designed biguanide (HL156A). Oncotarget, 2016, 10-04, Volume: 7, Issue:40 Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Proliferation; Dacarbazine; Drug Therapy, Combination; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Glioblastoma; Guanidines; Humans; Male; Mice; Mice, Inbred ICR; Mice, Nude; Neoplasm Invasiveness; Neoplastic Stem Cells; Pyrrolidines; Temozolomide; Tumor Cells, Cultured; Xenograft Model Antitumor Assays	2016
MiRNA203 suppresses the expression of protumorigenic STAT1 in glioblastoma to inhibit tumorigenesis. Oncotarget, 2016, Dec-20, Volume: 7, Issue:51 Topics: Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dacarbazine; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Interferons; Male; Mice, Inbred NOD; MicroRNAs; Neoplasm Invasiveness; RNA Interference; Signal Transduction; STAT1 Transcription Factor; Temozolomide; Time Factors; Transfection; Tumor Burden; Xenograft Model Antitumor Assays	2016
A Novel Computer-Assisted Approach to evaluate Multicellular Tumor Spheroid Invasion Assay. Scientific reports, 2016, 10-12, Volume: 6 Topics: Algorithms; Animals; Computer Simulation; Dacarbazine; Enzyme Inhibitors; Glioblastoma; Glioma; High-Throughput Screening Assays; Humans; Image Processing, Computer-Assisted; Imaging, Three-Dimensional; Mice; Neoplasm Invasiveness; Phosphotransferases (Alcohol Group Acceptor); Rats; Spheroids, Cellular; Temozolomide; Time-Lapse Imaging; Tumor Cells, Cultured	2016
Metformin treatment reduces temozolomide resistance of glioblastoma cells. Oncotarget, 2016, Nov-29, Volume: 7, Issue:48 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dacarbazine; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; Glioblastoma; Humans; Inhibitory Concentration 50; Metformin; Mice, SCID; Neoplasm Invasiveness; SOXB1 Transcription Factors; Temozolomide; Time Factors; Transcriptome; Tumor Burden; Xenograft Model Antitumor Assays	2016
Silencing of histone deacetylase 2 suppresses malignancy for proliferation, migration, and invasion of glioblastoma cells and enhances temozolomide sensitivity. Cancer chemotherapy and pharmacology, 2016, Volume: 78, Issue:6 Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dacarbazine; Glioblastoma; Histone Deacetylase 2; Humans; Multidrug Resistance-Associated Proteins; Neoplasm Invasiveness; RNA, Small Interfering; Temozolomide	2016
Refractory pituitary adenoma: a novel classification for pituitary tumors. Oncotarget, 2016, Dec-13, Volume: 7, Issue:50 Topics: Adenoma; Adult; Aged; Antineoplastic Agents, Alkylating; Biopsy; Cell Proliferation; Dacarbazine; Disease Progression; Drug Resistance, Neoplasm; Fatal Outcome; Female; Humans; Ki-67 Antigen; Magnetic Resonance Imaging; Male; Middle Aged; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Pituitary Neoplasms; Salvage Therapy; Temozolomide; Terminology as Topic; Time Factors; Treatment Outcome; Tumor Burden	2016
MiR-433-3p suppresses cell growth and enhances chemosensitivity by targeting CREB in human glioma. Oncotarget, 2017, Jan-17, Volume: 8, Issue:3 Topics: 3' Untranslated Regions; Adult; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cyclic AMP Response Element-Binding Protein; Dacarbazine; Down-Regulation; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Glioma; Humans; Male; MicroRNAs; Middle Aged; Neoplasm Invasiveness; Neoplasm Transplantation; Temozolomide; Young Adult	2017
The PI3K inhibitor GDC-0941 enhances radiosensitization and reduces chemoresistance to temozolomide in GBM cell lines. Neuroscience, 2017, 03-27, Volume: 346 Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Survival; Dacarbazine; Glioblastoma; Humans; Indazoles; Neoplasm Invasiveness; Phosphatidylinositol 3-Kinase; Phosphoinositide-3 Kinase Inhibitors; Radiation-Sensitizing Agents; Signal Transduction; Sulfonamides; Temozolomide	2017
[Adjuvant chemotherapy as a component of complex treatment for skin melanoma]. Voprosy onkologii, 2008, Volume: 54, Issue:2 Topics: Actuarial Analysis; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cisplatin; Cyclophosphamide; Dacarbazine; Disease-Free Survival; Doxorubicin; Female; Fluorouracil; Humans; Lymph Node Excision; Male; Melanoma; Methotrexate; Middle Aged; Neoadjuvant Therapy; Neoplasm Invasiveness; Neoplasm Staging; Radiotherapy, Adjuvant; Skin Neoplasms; Survival Analysis; Treatment Outcome; Vincristine	2008
Preclinical evaluation of dasatinib, a potent Src kinase inhibitor, in melanoma cell lines. Journal of translational medicine, 2008, Sep-29, Volume: 6 Topics: Antineoplastic Agents; Apoptosis; Benzenesulfonates; Blotting, Western; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dacarbazine; Dasatinib; Drug Screening Assays, Antitumor; Drug Synergism; Focal Adhesion Protein-Tyrosine Kinases; Humans; Melanoma; Neoplasm Invasiveness; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Proto-Oncogene Proteins pp60(c-src); Pyridines; Pyrimidines; Receptor, EphA2; Sorafenib; Temozolomide; Thiazoles	2008
Characterization of a side population of astrocytoma cells in response to temozolomide. Journal of neurosurgery, 2008, Volume: 109, Issue:5 Topics: Animals; Antineoplastic Agents, Alkylating; Astrocytoma; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Dacarbazine; Disease Models, Animal; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Glioma; Humans; Intermediate Filament Proteins; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Neoplasm Proteins; Nerve Tissue Proteins; Nestin; RNA-Binding Proteins; RNA, Small Interfering; Temozolomide; Xenograft Model Antitumor Assays	2008
Inhibition of PI3K-AKT-mTOR signaling sensitizes melanoma cells to cisplatin and temozolomide. The Journal of investigative dermatology, 2009, Volume: 129, Issue:6 Topics: Antineoplastic Agents, Alkylating; Apoptosis; Cell Line, Tumor; Cisplatin; Dacarbazine; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Humans; MAP Kinase Signaling System; Melanoma; Neoplasm Invasiveness; Phosphatidylinositol 3-Kinases; Protein Kinases; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Temozolomide; TOR Serine-Threonine Kinases	2009
Pseudoprogression after radiotherapy with concurrent temozolomide for high-grade glioma: clinical observations and working recommendations. Surgical neurology, 2009, Volume: 72, Issue:4 Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Diagnosis, Differential; Diagnostic Errors; Disease Progression; Female; Glioma; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Retrospective Studies; Temozolomide	2009
Editorial: on the road to multi-modal and pluri-disciplinary treatment of glioblastomas. Acta neurochirurgica, 2009, Volume: 151, Issue:2 Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; Dacarbazine; Drug Resistance; Glioblastoma; Humans; Neoplasm Invasiveness; Neurosurgical Procedures; Patient Care Team; Sodium-Potassium-Exchanging ATPase; Temozolomide	2009
Cilengitide modulates attachment and viability of human glioma cells, but not sensitivity to irradiation or temozolomide in vitro. Neuro-oncology, 2009, Volume: 11, Issue:6 Topics: Animals; Antineoplastic Agents, Alkylating; bcl-X Protein; Brain Neoplasms; Cell Adhesion; Cell Movement; Cell Proliferation; Cell Survival; Dacarbazine; DNA Methylation; Drug Therapy, Combination; Gene Silencing; Glioma; Humans; Immunoblotting; In Vitro Techniques; Integrin alphaVbeta3; Mice; Neoplasm Invasiveness; NIH 3T3 Cells; O(6)-Methylguanine-DNA Methyltransferase; Polymerase Chain Reaction; Promoter Regions, Genetic; Receptors, Vitronectin; Snake Venoms; Temozolomide; Tumor Cells, Cultured; Tumor Suppressor Protein p53	2009
Evidence of gamma-tocotrienol as an apoptosis-inducing, invasion-suppressing, and chemotherapy drug-sensitizing agent in human melanoma cells. Nutrition and cancer, 2009, Volume: 61, Issue:3 Topics: Antineoplastic Agents; Apoptosis; Cadherins; Cell Line, Tumor; Cell Proliferation; Chromans; Dacarbazine; Docetaxel; Humans; JNK Mitogen-Activated Protein Kinases; Melanoma; Neoplasm Invasiveness; Signal Transduction; Taxoids; Vitamin E	2009
Folate supplementation limits the aggressiveness of glioma via the remethylation of DNA repeats element and genes governing apoptosis and proliferation. Clinical cancer research : an official journal of the American Association for Cancer Research, 2009, May-15, Volume: 15, Issue:10 Topics: Aged; Apoptosis; Apoptosis Regulatory Proteins; Becaplermin; Cell Line, Tumor; Cell Proliferation; Dacarbazine; Dietary Supplements; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; DNA Methyltransferase 3B; DNA Modification Methylases; DNA Repair Enzymes; Folic Acid; Gene Expression Regulation, Neoplastic; Glioma; Humans; Inhibitor of Apoptosis Proteins; Microtubule-Associated Proteins; Middle Aged; Neoplasm Invasiveness; Platelet-Derived Growth Factor; Protein Binding; Proto-Oncogene Proteins c-sis; Repetitive Sequences, Nucleic Acid; Sp1 Transcription Factor; Sp3 Transcription Factor; Survival Analysis; Survivin; Temozolomide; Tumor Suppressor Proteins	2009
Hodgkin lymphoma with cutaneous involvement. Dermatology online journal, 2009, May-15, Volume: 15, Issue:5 Topics: Antigens, CD; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Dacarbazine; Doxorubicin; Hodgkin Disease; Humans; Lymph Nodes; Male; Middle Aged; Neoplasm Invasiveness; Reed-Sternberg Cells; Skin; Skin Ulcer; Vinblastine	2009
Increased vulnerability of the spinal cord to radiation or intrathecal chemotherapy during adolescence: A report from the Children's Oncology Group. Pediatric blood & cancer, 2009, Dec-15, Volume: 53, Issue:7 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Cranial Irradiation; Cyclophosphamide; Cytarabine; Dacarbazine; Dactinomycin; Etoposide; Female; Humans; Hydrocortisone; Injections, Spinal; Male; Meninges; Methotrexate; Myelitis; Neoplasm Invasiveness; Puberty; Radiation Injuries; Retrospective Studies; Rhabdomyosarcoma; Sarcoma, Ewing; Spinal Cord; Spinal Neoplasms; Vincristine	2009
Temozolomide (Temodar®) and capecitabine (Xeloda®) treatment of an aggressive corticotroph pituitary tumor. Pituitary, 2011, Volume: 14, Issue:4 Topics: ACTH-Secreting Pituitary Adenoma; Adenoma; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Dacarbazine; Deoxycytidine; Fluorouracil; Humans; Male; Middle Aged; Neoplasm Invasiveness; Radiography; Temozolomide; Treatment Outcome	2011
Esthesioneuroblastoma (Olfactory Neuroblastoma) with Ectopic ACTH Syndrome: a multidisciplinary case presentation from the Joan Karnell cancer center of Pennsylvania Hospital. The oncologist, 2010, Volume: 15, Issue:1 Topics: ACTH Syndrome, Ectopic; Adrenocorticotropic Hormone; Anti-Inflammatory Agents; Antifungal Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Hormonal; Dacarbazine; Esthesioneuroblastoma, Olfactory; Humans; Hydrocortisone; Immunohistochemistry; Ketoconazole; Magnetic Resonance Imaging; Male; Middle Aged; Nasal Cavity; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Nose Neoplasms; Octreotide; Temozolomide	2010
Long-term temozolomide treatment induces marked amino metabolism modifications and an increase in TMZ sensitivity in Hs683 oligodendroglioma cells. Neoplasia (New York, N.Y.), 2010, Volume: 12, Issue:1 Topics: Amino Acids; Animals; Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Western; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Dacarbazine; Female; Gene Expression Regulation, Neoplastic; Genomics; HT29 Cells; Humans; Mice; Mice, Nude; Neoplasm Invasiveness; Neoplastic Stem Cells; Oligodendroglioma; Proteomics; Reverse Transcriptase Polymerase Chain Reaction; Temozolomide; Time Factors; Xenograft Model Antitumor Assays	2010
Bevacizumab is active as a single agent against recurrent malignant gliomas. Anticancer research, 2010, Volume: 30, Issue:2 Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Dacarbazine; Doxorubicin; Female; Glioma; Humans; Lomustine; Male; Middle Aged; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Neoplasm Staging; Procarbazine; Retrospective Studies; Survival Rate; Temozolomide; Treatment Outcome; Vincristine	2010
Inhibition of metalloproteinases derived from tumours: new insights in the treatment of human glioblastoma. Neuroscience, 2010, Jun-30, Volume: 168, Issue:2 Topics: Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chemotaxis; Dacarbazine; Drug Interactions; Glioblastoma; Humans; Hydroxamic Acids; Matrix Metalloproteinase 2; Matrix Metalloproteinase Inhibitors; Neoplasm Invasiveness; Sulfonamides; Temozolomide	2010
Temozolomide treatment in aggressive pituitary tumors and pituitary carcinomas: a French multicenter experience. The Journal of clinical endocrinology and metabolism, 2010, Volume: 95, Issue:10 Topics: ACTH-Secreting Pituitary Adenoma; Adult; Antineoplastic Agents, Alkylating; Carcinoma; Dacarbazine; DNA Methylation; Female; France; Humans; Male; Middle Aged; Neoplasm Invasiveness; O(6)-Methylguanine-DNA Methyltransferase; Pituitary Neoplasms; Prolactinoma; Retrospective Studies; Sequence Analysis, DNA; Temozolomide	2010
Measurements of tumor cell autophagy predict invasiveness, resistance to chemotherapy, and survival in melanoma. Clinical cancer research : an official journal of the American Association for Cancer Research, 2011, May-15, Volume: 17, Issue:10 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Autophagy; Benzenesulfonates; Cell Count; Clinical Trials, Phase II as Topic; Dacarbazine; Drug Resistance, Neoplasm; Humans; Melanoma; Mice; Mice, Nude; Neoplasm Invasiveness; Niacinamide; Phenylurea Compounds; Prognosis; Pyridines; Skin Neoplasms; Sorafenib; Survival Analysis; Temozolomide; Tumor Cells, Cultured; Xenograft Model Antitumor Assays	2011
[Descriptive analysis of cutaneous recurrence patterns in patients with melanoma]. Actas dermo-sifiliograficas, 2011, Volume: 102, Issue:10 Topics: Aged; Aged, 80 and over; Aminoquinolines; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Dacarbazine; Female; Humans; Imiquimod; Kaplan-Meier Estimate; Lymph Node Excision; Male; Melanoma; Middle Aged; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Neoplasms, Multiple Primary; Prognosis; Skin Neoplasms; Skin Ulcer	2011
p53R2 is a prognostic factor of melanoma and regulates proliferation and chemosensitivity of melanoma cells. Journal of dermatological science, 2012, Volume: 68, Issue:1 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Child; Cisplatin; Cyclin-Dependent Kinase Inhibitor p21; Dacarbazine; Dose-Response Relationship, Drug; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Male; Melanoma; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Nimustine; Prognosis; Ribonucleotide Reductases; RNA Interference; Skin Neoplasms; Transfection; Vincristine; Young Adult	2012
Perillyl alcohol for the treatment of temozolomide-resistant gliomas. Molecular cancer therapeutics, 2012, Volume: 11, Issue:11 Topics: Administration, Intranasal; Animals; Brain Neoplasms; Cell Death; Cell Line, Tumor; Cell Proliferation; Cytokines; Dacarbazine; Drug Resistance, Neoplasm; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Glioma; Humans; Mice; Monoterpenes; Nelfinavir; Neoplasm Invasiveness; Neovascularization, Pathologic; Pyrazoles; Sulfonamides; Temozolomide; Xenograft Model Antitumor Assays	2012
Increased xCT expression correlates with tumor invasion and outcome in patients with glioblastomas. Neurosurgery, 2013, Volume: 72, Issue:1 Topics: Adult; Age Factors; Aged; Aged, 80 and over; Amino Acid Transport System y+; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease-Free Survival; DNA Modification Methylases; DNA Repair Enzymes; Excitatory Amino Acid Transporter 2; Female; Glioblastoma; Glutamate Plasma Membrane Transport Proteins; Humans; Immunohistochemistry; Isocitrate Dehydrogenase; Kaplan-Meier Estimate; Karnofsky Performance Status; Magnetic Resonance Imaging; Male; Middle Aged; Neoplasm Invasiveness; Neuropsychological Tests; Prognosis; Survival Analysis; Temozolomide; Treatment Outcome; Tumor Suppressor Proteins; Young Adult	2013
Knockdown of RLIP76 expression by RNA interference inhibits invasion, induces cell cycle arrest, and increases chemosensitivity to the anticancer drug temozolomide in glioma cells. Journal of neuro-oncology, 2013, Volume: 112, Issue:1 Topics: Antineoplastic Agents, Alkylating; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Cell Cycle Checkpoints; Cell Line, Tumor; Cyclin D1; Dacarbazine; Flow Cytometry; Gene Expression Regulation, Neoplastic; Glioma; Green Fluorescent Proteins; GTPase-Activating Proteins; Humans; Multidrug Resistance-Associated Proteins; Neoplasm Invasiveness; RNA Interference; RNA, Messenger; RNA, Small Interfering; Temozolomide; Time Factors; Transfection	2013
Temozolomide induces apoptosis and senescence in glioma cells cultured as multicellular spheroids. British journal of cancer, 2003, Feb-10, Volume: 88, Issue:3 Topics: Antineoplastic Agents, Alkylating; Apoptosis; Cell Division; Cell Movement; Cellular Senescence; Dacarbazine; DNA Fragmentation; Drug Resistance, Neoplasm; Glioma; Humans; In Situ Nick-End Labeling; Neoplasm Invasiveness; Spheroids, Cellular; Temozolomide; Tumor Cells, Cultured	2003
Impact of chest wall and lung invasion on outcome of stage I-II Hodgkin's lymphoma after combined modality therapy. International journal of radiation oncology, biology, physics, 2003, Dec-01, Volume: 57, Issue:5 Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modality Therapy; Dacarbazine; Doxorubicin; Female; Hodgkin Disease; Humans; Lung Neoplasms; Male; Mechlorethamine; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Prednisone; Procarbazine; Radiotherapy; Recurrence; Retrospective Studies; Survival Analysis; Thoracic Wall; Vinblastine; Vincristine	2003
Extended total sacrectomy and reconstruction for sacral tumor. Spine, 2004, Mar-15, Volume: 29, Issue:6 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Dacarbazine; Diagnostic Errors; Doxorubicin; Fibula; Follow-Up Studies; Humans; Ifosfamide; Ilium; Internal Fixators; Intervertebral Disc Displacement; Laminectomy; Lumbar Vertebrae; Male; Mesna; Neoadjuvant Therapy; Neoplasm Invasiveness; Radiotherapy, Adjuvant; Recovery of Function; Rhizotomy; Sacrum; Sarcoma; Spinal Neoplasms; Spinal Nerve Roots	2004
Extraskeletal Ewing sarcoma of the diaphragm presenting with hemothorax. The Annals of thoracic surgery, 2004, Volume: 78, Issue:2 Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Child; Combined Modality Therapy; Dacarbazine; Doxorubicin; Dyspnea; Female; Hemothorax; Humans; Ifosfamide; Mesna; Muscle Neoplasms; Neoplasm Invasiveness; Organ Specificity; Radiotherapy, Adjuvant; Remission Induction; Ribs; Sarcoma, Ewing	2004
Gliomatosis cerebri: better definition, better treatment. Neurology, 2004, Jul-27, Volume: 63, Issue:2 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Astrocytes; Astrocytoma; Brain; Brain Neoplasms; Cell Cycle Proteins; Dacarbazine; Disease Progression; Female; Humans; Lomustine; Magnetic Resonance Imaging; Male; Middle Aged; Neoplasm Invasiveness; Neoplasm Proteins; Neoplasms, Neuroepithelial; Nerve Tissue Proteins; Procarbazine; Temozolomide; Vincristine	2004
Gastrin exerts pleiotropic effects on human melanoma cell biology. Neoplasia (New York, N.Y.), 2005, Volume: 7, Issue:10 Topics: Actins; Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Line, Tumor; Cell Movement; Cholecystokinin; Cisplatin; Cytoskeleton; Dacarbazine; DNA Primers; DNA, Complementary; Flow Cytometry; Gastrins; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Immunohistochemistry; Melanoma; Mice; Neoplasm Invasiveness; Neoplasm Transplantation; Neovascularization, Pathologic; Oligonucleotide Array Sequence Analysis; Poly(ADP-ribose) Polymerases; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Time Factors; Wound Healing	2005
Serial monitoring of circulating melanoma cells during neoadjuvant biochemotherapy for stage III melanoma: outcome prediction in a multicenter trial. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Nov-01, Volume: 23, Issue:31 Topics: Adolescent; Adult; Aged; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Chemotherapy, Adjuvant; Cisplatin; Dacarbazine; Female; Humans; Interferon-alpha; Interleukin-2; Male; MART-1 Antigen; Melanoma; Middle Aged; N-Acetylgalactosaminyltransferases; Neoadjuvant Therapy; Neoplasm Invasiveness; Neoplasm Proteins; Neoplasm Recurrence, Local; Neoplastic Cells, Circulating; Paired Box Transcription Factors; PAX3 Transcription Factor; Prospective Studies; Reverse Transcriptase Polymerase Chain Reaction; Risk Factors; RNA, Messenger; RNA, Neoplasm; Skin Neoplasms; Survival Rate; Treatment Outcome; Vinblastine	2005
Pro-invasive gene regulating effect of irradiation and combined temozolomide-radiation treatment on surviving human malignant glioma cells. European journal of pharmacology, 2006, Aug-07, Volume: 542, Issue:1-3 Topics: Antineoplastic Agents, Alkylating; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dacarbazine; Glioma; Humans; Matrix Metalloproteinase 14; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Temozolomide; Tissue Inhibitor of Metalloproteinase-2; Up-Regulation	2006
Development of luciferase tagged brain tumour models in mice for chemotherapy intervention studies. European journal of cancer (Oxford, England : 1990), 2006, Volume: 42, Issue:18 Topics: Animals; Antineoplastic Agents, Alkylating; Blood-Brain Barrier; Brain Neoplasms; Cell Division; Cell Line, Tumor; Contrast Media; Dacarbazine; Drug Screening Assays, Antitumor; Female; Gadolinium DTPA; Immunohistochemistry; Luciferases; Luminescence; Magnetic Resonance Imaging; Male; Mice; Mice, Nude; Neoplasm Invasiveness; Temozolomide	2006
Magnetic resonance imaging determination of tumor grade and early response to temozolomide in a genetically engineered mouse model of glioma. Clinical cancer research : an official journal of the American Association for Cancer Research, 2007, May-15, Volume: 13, Issue:10 Topics: Animals; Brain Neoplasms; Dacarbazine; Disease Models, Animal; Genetic Engineering; Glioma; Magnetic Resonance Imaging; Mice; Mice, Mutant Strains; Neoplasm Invasiveness; Neoplasm Staging; Prognosis; Retroviridae; Temozolomide	2007
[The sodium pump could constitute a new target to combat glioblastomas]. Bulletin du cancer, 2008, Volume: 95, Issue:3 Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Apoptosis; Autophagy; Brain Neoplasms; Calotropis; Cardenolides; Cell Movement; Cell Proliferation; Combined Modality Therapy; Dacarbazine; Drug Screening Assays, Antitumor; Glioblastoma; Humans; Mice; Neoplasm Invasiveness; Neoplasm Proteins; Neovascularization, Pathologic; Signal Transduction; Sodium-Potassium-Exchanging ATPase; Temozolomide	2008
Prevention of irradiation-induced glioma cell invasion by temozolomide involves caspase 3 activity and cleavage of focal adhesion kinase. Cancer research, 2002, Mar-15, Volume: 62, Issue:6 Topics: 3T3 Cells; Animals; Antineoplastic Agents, Alkylating; Caspase 3; Caspases; Combined Modality Therapy; Dacarbazine; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Glioma; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases, Membrane-Associated; Metalloendopeptidases; Mice; Neoplasm Invasiveness; Protein-Tyrosine Kinases; Rats; Receptors, Vitronectin; Temozolomide; Tumor Cells, Cultured; Up-Regulation	2002
[The malignant melanoma: criteria for the prognosis and therapy]. Schweizerische medizinische Wochenschrift, 1978, Sep-02, Volume: 108, Issue:35 Topics: Dacarbazine; Female; Humans; Lymph Nodes; Male; Melanoma; Neoplasm Invasiveness; Neoplasm Staging; Patient Care Planning; Prognosis	1978
The prognosis of melanoma patients with metastases to two or more lymph node areas. Annals of surgery, 1991, Volume: 214, Issue:2 Topics: Adolescent; Adult; BCG Vaccine; Combined Modality Therapy; Dacarbazine; Female; Humans; Immunotherapy; Lomustine; Lymph Node Excision; Lymphatic Metastasis; Male; Melanoma; Middle Aged; Neoplasm Invasiveness; Prognosis; Skin Neoplasms; Survival Rate	1991
Chemotherapy for aggressive juvenile nasopharyngeal angiofibroma. Archives of otolaryngology (Chicago, Ill. : 1960), 1985, Volume: 111, Issue:5 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Dacarbazine; Dactinomycin; Doxorubicin; Follow-Up Studies; Histiocytoma, Benign Fibrous; Humans; Male; Nasopharyngeal Neoplasms; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Tomography, X-Ray Computed; Vincristine	1985