dacarbazine and Colorectal Neoplasms

dacarbazine has been researched along with Colorectal Neoplasms in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.23)18.7374
1990's6 (19.35)18.2507
2000's7 (22.58)29.6817
2010's16 (51.61)24.3611
2020's1 (3.23)2.80

Authors

AuthorsStudies
Amatu, A; Barault, L; Bardelli, A; Bartolini, A; Battuello, P; Bonoldi, E; Cassingena, A; Crisafulli, G; Di Nicolantonio, F; Germano, G; Idotta, L; Lazzari, L; Luraghi, P; Macagno, M; Marsoni, S; Mauri, G; Morano, F; Personeni, N; Pessei, V; Pietrantonio, F; Sartore-Bianchi, A; Siena, S; Tosi, F; Valtorta, E; Vitiello, PP; Zampino, MG1
Barbaro, B; Barone, C; Basso, M; Calegari, MA; Camarda, F; Cassano, A; Cenci, T; de Pascalis, I; Gori, S; Inno, A; Larocca, LM; Martini, M; Monterisi, S; Orlandi, A; Santini, D; Tonini, G1
Amatu, A; Belotti, A; Bencardino, K; Cassingena, A; Chirico, G; Esposito, A; Esteller, M; Moutinho, C; Nichelatti, M; Rusconi, F; Sartore-Bianchi, A; Siena, S1
Doyle, TJ; Glynne-Jones, R; Grávalos, C; Hochhauser, D; Pathiraja, K; Potter, V; Sausville, EA; Zhang, L; Zhang, Q1
Biondani, P; Bossi, I; Busico, A; Castano, A; de Braud, F; Di Bartolomeo, M; Festinese, F; Gariboldi, M; Gevorgyan, A; Maggi, C; Pacifici, M; Perrone, F; Pietrantonio, F; Tamborini, E1
Hromas, R; Jaiswal, AS; Jani, J; Law, BK; Narayan, S; Panda, H; Sharma, J1
Dörsam, B; Fahrer, J; Göder, A; Kaina, B; Kraus, A; Nagel, G; Seiwert, N1
Amatu, A; Barault, L; Bardelli, A; Bleeker, FE; Cassingena, A; Cassoni, P; De Braud, F; de Witt Hamer, P; Di Nicolantonio, F; Esteller, M; Falcomatà, C; Fiano, V; Milione, M; Moutinho, C; Pietrantonio, F; Rudà, R; Sartore-Bianchi, A; Siena, S; Siravegna, G; Soffietti, R; Venesio, T; Wesseling, P1
Berenato, R; Bossi, I; Caporale, M; de Braud, F; Di Bartolomeo, M; Dotti, KF; Federici, S; Festinese, F; Iacovelli, R; Leone, G; Maggi, C; Milione, M; Pellegrinelli, A; Perrone, F; Pietrantonio, F; Tamborini, E1
Baryawno, N; Calero, R; Darabi, A; Dyberg, C; Einvik, C; Johnsen, JI; Kogner, P; Kool, M; Milosevic, J; Sandén, E; Siesjö, P; Sveinbjörnsson, B; Wickström, M1
Amatu, A; Barault, L; Bardelli, A; Bencardino, K; Bonazzina, E; Cassingena, A; Chirico, G; Cipani, T; Crivori, P; Di Nicolantonio, F; Esteller, M; Gatto, R; Ghezzi, S; Marrapese, G; Moutinho, C; Palmeri, L; Ricotta, R; Sartore-Bianchi, A; Siena, S; Tosi, F; Truini, M1
An, X; Ba, Y; Chen, C; Huang, P; Li, C; Li, Y; Wang, D; Wang, F; Xu, R; Zeng, J; Zeng, Z; Zhang, L1
Amatu, A; Barault, L; Bardelli, A; Berenato, R; Caporale, M; Cassingena, A; De Braud, F; Di Nicolantonio, F; Falcomatà, C; Ghezzi, S; Milione, M; Nichelatti, M; Pellegrinelli, A; Pietrantonio, F; Sartore-Bianchi, A; Siena, S; Tosi, F1
Aderka, D; Beny, A; Blachar, A; Figer, A; Geva, R; Shacham-Shmueli, E1
Aneja, R; Banerjee, S; Jaiswal, AS; Narayan, S; Ostrov, DA; Sarkar, FH1
Bradshaw, TD; Hummersone, M; Laughton, CA; Madhusudan, S; Stevens, MF; Zhang, J1
Borden, EC; Budd, TG; Elson, P; Hollovary, E; Jacobs, B; Mitsuhashi, M; Spiro, T; Triozzi, P; Yi, T1
Almassy, R; Barton, S; Batey, MA; Calabrese, CR; Calvert, AH; Canan-Koch, S; Curtin, NJ; Durkacz, BW; Hostomsky, Z; Kumpf, RA; Kyle, S; Li, J; Maegley, K; Newell, DR; Notarianni, E; Skalitzky, D; Stratford, IJ; Thomas, HD; Wang, LZ; Webber, SE; Williams, KJ1
Curtin, NJ; Eastman, BW; Golding, BT; Griffin, RJ; Hostomsky, Z; Kyle, S; Li, J; Maegley, KA; Skalitzky, DJ; Webber, SE; White, AW; Yu, XH1
Akbulut, H; Buyukcelik, A; Demirkazik, A; Icli, F; Onur, H; Utkan, G; Yalcin, B1
Batey, MA; Calabrese, CR; Canan, S; Curtin, NJ; Hostomsky, Z; Kyle, S; Maegley, KA; Newell, DR; Skalitzky, D; Thomas, HD; Wang, LZ; Webber, SE1
Ilson, DH; Krol, G; Ku, GY1
Ng, W; Steckley, JL; Watling, CJ1
Khan, OA; Levitt, NC; Margison, GP; Michael, M; Middleton, MR; Midgley, R; Mortimer, P; Olver, I; Ranson, M; Watson, AJ1
Aschele, C; Bolli, E; Guglielmi, A; Mori, A; Nobile, MT; Rosso, R; Sobrero, A; Tixi, L1
Brock, CS; Cunningham, VJ; Harte, RJ; Jones, T; Matthews, JC; Meikle, SR; Price, P; Wells, P1
Akbulut, H; Arican, A; Cay, F; Demirkazik, A; Dinçol, D; Içli, F; Karaoğuz, H1
Bocsi, J; Hidvégi, M; Lapis, K; Paku, S; Prónai, L; Rásó, E; Szende, B; Tömösközi-Farkas, R1
Gazit, Z; Kedar, E; Notter, M; Schirrmacher, V; Shouval, D; Walter, J; Weiss, DW; Yechezkeli, M1
Blackledge, GR; Brampton, MH; Hoffman, R; Newlands, ES; Quarterman, CP; Rustin, GJ; Slack, JA; Smith, DB; Stevens, MF; Stuart, NS1
Droz, JP; Herait, P; Kac, JL; Rougier, P; Theodore, C1

Trials

11 trial(s) available for dacarbazine and Colorectal Neoplasms

ArticleYear
Temozolomide Treatment Alters Mismatch Repair and Boosts Mutational Burden in Tumor and Blood of Colorectal Cancer Patients.
    Cancer discovery, 2022, 07-06, Volume: 12, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Colorectal Neoplasms; Dacarbazine; DNA Mismatch Repair; DNA-Binding Proteins; Humans; Mutation; O(6)-Methylguanine-DNA Methyltransferase; Temozolomide

2022
A phase 2 study of temozolomide in pretreated metastatic colorectal cancer with MGMT promoter methylation.
    British journal of cancer, 2017, May-09, Volume: 116, Issue:10

    Topics: Aged; Aged, 80 and over; Anemia; Antineoplastic Agents, Alkylating; Colorectal Neoplasms; Dacarbazine; Disease-Free Survival; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Female; GTP Phosphohydrolases; Humans; Membrane Proteins; Middle Aged; Mutation; Nausea; Neoplasm Metastasis; Promoter Regions, Genetic; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins p21(ras); Retreatment; Survival Rate; Temozolomide; Thrombocytopenia; Treatment Outcome; Tumor Suppressor Proteins; Vomiting

2017
Promoter CpG island hypermethylation of the DNA repair enzyme MGMT predicts clinical response to dacarbazine in a phase II study for metastatic colorectal cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2013, Apr-15, Volume: 19, Issue:8

    Topics: Administration, Intravenous; Adult; Aged; Aged, 80 and over; Anemia; Antineoplastic Agents, Alkylating; Colorectal Neoplasms; Constipation; CpG Islands; Dacarbazine; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Double-Blind Method; Drug Administration Schedule; Fatigue; Female; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Nausea; Prognosis; Promoter Regions, Genetic; Treatment Outcome; Tumor Suppressor Proteins

2013
A phase II study of temozolomide in patients with advanced aerodigestive tract and colorectal cancers and methylation of the O6-methylguanine-DNA methyltransferase promoter.
    Molecular cancer therapeutics, 2013, Volume: 12, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Colorectal Neoplasms; Dacarbazine; DNA Methylation; DNA Mismatch Repair; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Neoplasm Staging; O(6)-Methylguanine-DNA Methyltransferase; Promoter Regions, Genetic; Temozolomide; Treatment Outcome

2013
Activity of temozolomide in patients with advanced chemorefractory colorectal cancer and MGMT promoter methylation.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2014, Volume: 25, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Colorectal Neoplasms; Dacarbazine; Disease-Free Survival; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Drug Resistance, Neoplasm; Female; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Promoter Regions, Genetic; Temozolomide; Treatment Outcome; Tumor Suppressor Proteins

2014
Tumor MGMT promoter hypermethylation changes over time limit temozolomide efficacy in a phase II trial for metastatic colorectal cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2016, Volume: 27, Issue:6

    Topics: Adult; Aged; Biomarkers, Tumor; Biopsy; Colorectal Neoplasms; Dacarbazine; Disease-Free Survival; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Female; Humans; Male; Middle Aged; Promoter Regions, Genetic; Temozolomide; Tumor Suppressor Proteins

2016
Digital PCR assessment of MGMT promoter methylation coupled with reduced protein expression optimises prediction of response to alkylating agents in metastatic colorectal cancer patients.
    European journal of cancer (Oxford, England : 1990), 2017, Volume: 71

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Colorectal Neoplasms; Dacarbazine; DNA Methylation; DNA Modification Methylases; Female; Humans; Immunohistochemistry; Male; Middle Aged; Multivariate Analysis; O(6)-Methylguanine-DNA Methyltransferase; Polymerase Chain Reaction; Predictive Value of Tests; Promoter Regions, Genetic; Retrospective Studies; Survival Analysis; Temozolomide

2017
Phosphatase inhibitor, sodium stibogluconate, in combination with interferon (IFN) alpha 2b: phase I trials to identify pharmacodynamic and clinical effects.
    Oncotarget, 2011, Volume: 2, Issue:12

    Topics: Adult; Aged; Antimony Sodium Gluconate; Antineoplastic Agents; Breast Neoplasms; Cisplatin; Colorectal Neoplasms; Dacarbazine; Drug Therapy, Combination; Enzyme Inhibitors; Female; Gastrointestinal Stromal Tumors; Humans; Interferon alpha-2; Interferon-alpha; Male; Melanoma; Middle Aged; Phosphoric Monoester Hydrolases; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Recombinant Proteins; Sarcoma; Vinblastine

2011
A phase II trial of lomeguatrib and temozolomide in metastatic colorectal cancer.
    British journal of cancer, 2008, May-20, Volume: 98, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Dacarbazine; Disease Progression; Female; Humans; Male; Middle Aged; Neoplasm Staging; Purines; Temozolomide; Treatment Failure

2008
Phase II study of cisplatin and dacarbazine for metastatic colorectal carcinoma resistant to 5-fluorouracil.
    Oncology, 1999, Volume: 56, Issue:4

    Topics: Adult; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Colorectal Neoplasms; Dacarbazine; Drug Resistance, Neoplasm; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasm Staging; Treatment Outcome

1999
Phase I trial of temozolomide (CCRG 81045: M&B 39831: NSC 362856).
    British journal of cancer, 1992, Volume: 65, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Breast Neoplasms; Colorectal Neoplasms; Dacarbazine; Drug Administration Schedule; Drug Evaluation; Female; Glioma; Humans; Kidney Neoplasms; Male; Melanoma; Middle Aged; Neoplasms; Stomach Neoplasms; Temozolomide

1992

Other Studies

20 other study(ies) available for dacarbazine and Colorectal Neoplasms

ArticleYear
NSC666715 and Its Analogs Inhibit Strand-Displacement Activity of DNA Polymerase β and Potentiate Temozolomide-Induced DNA Damage, Senescence and Apoptosis in Colorectal Cancer Cells.
    PloS one, 2015, Volume: 10, Issue:5

    Topics: Apoptosis; Benzothiazoles; Cell Cycle; Cell Cycle Checkpoints; Cellular Senescence; Colorectal Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Dacarbazine; DNA Damage; DNA Polymerase beta; DNA Repair; Enzyme Inhibitors; HCT116 Cells; Humans; Small Molecule Libraries; Sulfhydryl Compounds; Sulfonamides; Temozolomide; Toluene; Triazoles; Tumor Suppressor Protein p53

2015
Lipoic acid inhibits the DNA repair protein O 6-methylguanine-DNA methyltransferase (MGMT) and triggers its depletion in colorectal cancer cells with concomitant autophagy induction.
    Carcinogenesis, 2015, Volume: 36, Issue:8

    Topics: Animals; Antineoplastic Agents, Alkylating; Autophagy; Colorectal Neoplasms; Cysteine; Dacarbazine; DNA Modification Methylases; DNA Repair; DNA Repair Enzymes; Drug Resistance, Neoplasm; Female; Glutathione; Guanine; HCT116 Cells; Humans; Male; Mice, Inbred BALB C; Molecular Targeted Therapy; Temozolomide; Thioctic Acid; Tumor Suppressor Proteins; Xenograft Model Antitumor Assays

2015
Digital PCR quantification of MGMT methylation refines prediction of clinical benefit from alkylating agents in glioblastoma and metastatic colorectal cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2015, Volume: 26, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Colorectal Neoplasms; Dacarbazine; Disease-Free Survival; DNA; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Glioblastoma; Humans; Polymerase Chain Reaction; Prognosis; Promoter Regions, Genetic; Temozolomide; Tumor Suppressor Proteins

2015
Dose-Dense Temozolomide in Patients with MGMT-Silenced Chemorefractory Colorectal Cancer.
    Targeted oncology, 2016, Volume: 11, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Colorectal Neoplasms; Dacarbazine; Humans; Middle Aged; Temozolomide

2016
Wnt/β-catenin pathway regulates MGMT gene expression in cancer and inhibition of Wnt signalling prevents chemoresistance.
    Nature communications, 2015, Nov-25, Volume: 6

    Topics: Animals; Antineoplastic Agents; Benzeneacetamides; beta Catenin; Brain Neoplasms; Camptothecin; Celecoxib; Cisplatin; Colorectal Neoplasms; Dacarbazine; DNA Modification Methylases; DNA Repair Enzymes; Doxorubicin; Drug Resistance, Neoplasm; Flow Cytometry; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glioma; Glucose-6-Phosphate Isomerase; Heterocyclic Compounds, 3-Ring; Humans; Immunoblotting; Immunohistochemistry; Irinotecan; Medulloblastoma; Mice; Neoplasm Transplantation; Neoplasms; Neuroblastoma; Pyrans; Pyrazines; Pyridines; Real-Time Polymerase Chain Reaction; Sulfones; Temozolomide; Triazoles; Tumor Suppressor Proteins; Vincristine; Wnt Proteins; Wnt Signaling Pathway

2015
MGMT in colorectal cancer: a promising component of personalized treatment.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2016, Volume: 37, Issue:8

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Blotting, Western; Cell Line, Tumor; Colorectal Neoplasms; Dacarbazine; Disease-Free Survival; DNA Modification Methylases; DNA Repair Enzymes; Drug Resistance, Neoplasm; Female; Humans; Immunohistochemistry; Kaplan-Meier Estimate; Male; Middle Aged; Precision Medicine; Prognosis; Proportional Hazards Models; Temozolomide; Tumor Suppressor Proteins

2016
Response to temozolomide in patients with metastatic colorectal cancer with loss of MGMT expression: a new approach in the era of personalized medicine?
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Apr-01, Volume: 29, Issue:10

    Topics: Adenocarcinoma; Aged; Antineoplastic Agents, Alkylating; Biopsy; Colectomy; Colorectal Neoplasms; Dacarbazine; DNA Modification Methylases; DNA Repair Enzymes; Down-Regulation; Female; Humans; Immunohistochemistry; Liver Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Staging; Positron-Emission Tomography; Precision Medicine; Temozolomide; Tomography, X-Ray Computed; Treatment Outcome; Tumor Suppressor Proteins

2011
DNA polymerase β as a novel target for chemotherapeutic intervention of colorectal cancer.
    PloS one, 2011, Feb-02, Volume: 6, Issue:2

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Caco-2 Cells; Carcinoma; Cell Line, Tumor; Colorectal Neoplasms; Dacarbazine; DNA Polymerase beta; Drug Synergism; Female; HCT116 Cells; HT29 Cells; Humans; Mice; Mice, SCID; Molecular Targeted Therapy; Organophosphates; Pyrimidinones; Temozolomide; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2011
Certain imidazotetrazines escape O6-methylguanine-DNA methyltransferase and mismatch repair.
    Oncology, 2011, Volume: 80, Issue:3-4

    Topics: Antineoplastic Agents, Alkylating; Cell Cycle; Cell Line, Tumor; Colorectal Neoplasms; Dacarbazine; DNA Mismatch Repair; DNA Repair; DNA, Neoplasm; Drug Resistance, Neoplasm; Glioma; Humans; Imidazoles; O(6)-Methylguanine-DNA Methyltransferase; Pilot Projects; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Promoter Regions, Genetic; Temozolomide

2011
Anticancer chemosensitization and radiosensitization by the novel poly(ADP-ribose) polymerase-1 inhibitor AG14361.
    Journal of the National Cancer Institute, 2004, Jan-07, Volume: 96, Issue:1

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Azulenes; Benzodiazepines; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Colorectal Neoplasms; Dacarbazine; Drug Resistance, Neoplasm; Enzyme Inhibitors; Gamma Rays; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Mice; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Radiation-Sensitizing Agents; Temozolomide; Transplantation, Heterologous

2004
Potentiation of cytotoxic drug activity in human tumour cell lines, by amine-substituted 2-arylbenzimidazole-4-carboxamide PARP-1 inhibitors.
    Bioorganic & medicinal chemistry letters, 2004, May-17, Volume: 14, Issue:10

    Topics: Amides; Animals; Antineoplastic Agents; Benzimidazoles; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Dacarbazine; Drug Synergism; Humans; Lung Neoplasms; Poly(ADP-ribose) Polymerase Inhibitors; Structure-Activity Relationship; Temozolomide

2004
Activity of irinotecan, cisplatin and dacarbazine (CPD) combination in previously treated patients with advanced colorectal carcinoma.
    Experimental oncology, 2004, Volume: 26, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Camptothecin; Cisplatin; Colorectal Neoplasms; Dacarbazine; Disease-Free Survival; Female; Humans; Irinotecan; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Survival Rate; Treatment Outcome

2004
Preclinical selection of a novel poly(ADP-ribose) polymerase inhibitor for clinical trial.
    Molecular cancer therapeutics, 2007, Volume: 6, Issue:3

    Topics: Animals; Antineoplastic Agents; Benzodiazepines; Cell Line, Tumor; Colorectal Neoplasms; Dacarbazine; DNA Repair; Drug Evaluation, Preclinical; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Female; Gamma Rays; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Heterocyclic Compounds, 3-Ring; Humans; Maximum Tolerated Dose; Mice; Mice, Nude; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Structure-Activity Relationship; Temozolomide; Topoisomerase I Inhibitors; Topotecan

2007
Successful treatment of leptomeningeal disease in colorectal cancer with a regimen of bevacizumab, temozolomide, and irinotecan.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2007, May-01, Volume: 25, Issue:13

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Colorectal Neoplasms; Dacarbazine; Humans; Irinotecan; Magnetic Resonance Imaging; Male; Meningeal Neoplasms; Middle Aged; Temozolomide; Treatment Outcome

2007
Glioblastoma in a patient with a hereditary cancer syndrome.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2008, Volume: 35, Issue:1

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cerebral Hemorrhage; Colorectal Neoplasms; Combined Modality Therapy; Dacarbazine; Glioblastoma; Headache; Humans; International Normalized Ratio; Male; Neurosurgical Procedures; Pedigree; Temozolomide; Tomography, X-Ray Computed

2008
Dacarbazine and fotemustine in advanced colorectal cancer.
    European journal of cancer (Oxford, England : 1990), 1993, Volume: 29A, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Dacarbazine; Female; Humans; Male; Middle Aged; Nitrosourea Compounds; Organophosphorus Compounds

1993
Pharmacokinetic assessment of novel anti-cancer drugs using spectral analysis and positron emission tomography: a feasibility study.
    Cancer chemotherapy and pharmacology, 1998, Volume: 42, Issue:3

    Topics: Acridines; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Colorectal Neoplasms; Dacarbazine; Feasibility Studies; Female; Fluorouracil; Glioma; Humans; Middle Aged; Spectrum Analysis; Temozolomide; Tomography, Emission-Computed

1998
MSC, a new benzoquinone-containing natural product with antimetastatic effect.
    Cancer biotherapy & radiopharmaceuticals, 1999, Volume: 14, Issue:4

    Topics: Animals; Benzoquinones; Colonic Neoplasms; Colorectal Neoplasms; Dacarbazine; Humans; Lectins; Liver Neoplasms; Lung Neoplasms; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Neoplasm Metastasis; Plant Extracts; Transplantation, Heterologous

1999
Chemo-adoptive immunotherapy of nude mice implanted with human colorectal carcinoma and melanoma cell lines.
    Cancer immunology, immunotherapy : CII, 1992, Volume: 35, Issue:2

    Topics: Animals; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Combined Modality Therapy; Cytotoxicity, Immunologic; Dacarbazine; Drug Administration Schedule; Female; Fluorouracil; Humans; Immunotherapy, Adoptive; Interferon Type I; Interleukin-2; Killer Cells, Lymphokine-Activated; Lymphocytes, Tumor-Infiltrating; Male; Melanoma; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Recombinant Proteins; T-Lymphocytes; Tumor Cells, Cultured

1992
Alternating 5-FU-mitomycin C/5-FU-dacarbazine in advanced colorectal adenocarcinoma: a phase II study.
    Oncology, 1989, Volume: 46, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Dacarbazine; Drug Administration Schedule; Drug Evaluation; Female; Fluorouracil; Humans; Male; Middle Aged; Mitomycin; Mitomycins

1989