Compounds > dacarbazine

dacarbazine and Cell Transformation, Neoplastic

dacarbazine has been researched along with Cell Transformation, Neoplastic in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.33)18.7374
1990's1 (3.33)18.2507
2000's5 (16.67)29.6817
2010's23 (76.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kang, CS; Lv, SG; Wang, QX; Wu, MJ; Xiao, B; Xu, B; Ye, MH; Zhu, XG1
Lenders, N; McCormack, A1
Cabezas, SS; Dos Santos, SN; Helal-Neto, E; Martínez-Máñez, R; Pinto, SR; Portilho, FL; Pozzo, L; Sancenón, F; Santos-Oliveira, R1
Furuta, T; Hamada, J; Hayashi, Y; Misaki, K; Nakada, M; Nakanuma, Y; Sato, Y1
Agostinis, P; Govaere, O; Gremeaux, L; Maes, H; Roskams, T; Stas, M; Van den Broeck, A; van den Oord, JJ; Vankelecom, H; Wouters, J1
Barzo, P; Cserhati, A; Fodor, E; Hideghety, K; Mozes, P; Szanto, E; Tiszlavicz, L1
Ahmed, AU; Auffinger, B; Dey, M; Guo, D; Han, Y; Lee, G; Lesniak, MS; Tobias, AL1
Chen, J; Fu, X; Jiang, D; Shi, L; Wan, Y; Wang, Z1
Chen, YS; Chen, ZP; Guan, S; Guo, CC; Li, WP; Li, WY; Mou, YG; Sai, K; Wang, J; Yang, QY1
Mukherjee, J; Ohba, S; Pieper, RO; See, WL1
Cantelli, E; De Vries, S; Dekker, M; Delzenne-Goette, E; Plug, M; Song, JY; Te Riele, H; Van Der Wal, A; Van Gerwen, B; Wojciechowicz, K1
Nam, DH; Park, C; Yeom, SY1
Dempsey, RJ; Kuo, JS; Pointer, KB; Zhang, RR1
Hirohata, T; Ishii, Y; Matsuno, A1
Hutchinson, L1
Baronchelli, S; Bentivegna, A; Butta, V; Cilibrasi, C; Dalprà, L; Lavitrano, M; Redaelli, S; Riva, G1
Botelho, RV; de Oliveira, MF; Reis, RC; Rotta, JM1
Cheung, NK; Kramer, K; Kushner, BH; Laquaglia, MP; Modak, S1
Brathwaite, CD; Sandberg, DI; Zoeller, GK1
Asano, S; Ishida, Y; Katakami, H; Matsuno, A; Mizutani, A; Murakami, M; Okinaga, H; Ozawa, Y; Takano, K; Yamazaki, K1
Fukushima, T; Inoue, T; Kawaguchi, H; Komatsu, F; Komatsu, M; Nabeshima, K; Oshiro, S; Tsugu, H1
Chang, YL; Chen, MT; Chen, YW; Cherng, JY; Chien, Y; Chiou, GY; Chiou, SH; Huang, PI; Lo, WL; Shih, YH; Wang, ML; Yang, YP1
Chen, Y; Dallaglio, K; Fujita, M; Gonzalez, R; Luo, Y; McCarter, MD; Norris, DA; Robinson, SE; Robinson, WA; Roop, DR; Thompson, DC; Vasiliou, V; Wang, J1
Consales, A; Garrè, ML; Morana, G; Nozza, P; Piccardo, A; Rossi, A1
Forini, O; Graziani, G; Lacal, PM; Levati, L; Muzi, A; Ruffini, F; Tentori, L; Vergati, M; Vernole, P1
Erickson, LC; Gibson, NW; Hickman, JA1
Cobellis, L; Di Re, E; Grosso, G; Quattrone, P; Raspagliesi, F1
Bolger, MJ; Kaleem, Z; O'Sullivan, MJ; Swanson, PE; Zutter, MM1
Ebsen, M; Kirchner, EM; Kirchner, J; Theegarten, D; Voigtmann, R1
Chen, SH; Liang, YC; Lin, CL; Liu, JD; Tsai, SH1

Reviews

2 review(s) available for dacarbazine and Cell Transformation, Neoplastic

ArticleYear
Malignant transformation in non-functioning pituitary adenomas (pituitary carcinoma).
    Pituitary, 2018, Volume: 21, Issue:2

    Topics: Adenoma; Animals; Cell Transformation, Neoplastic; Dacarbazine; Humans; Pituitary Neoplasms; Temozolomide

2018
Treatment of pituitary carcinomas and atypical pituitary adenomas: a review.
    Neurologia medico-chirurgica, 2014, Volume: 54, Issue:12

    Topics: Adenoma; Administration, Oral; Antineoplastic Agents, Alkylating; Cell Transformation, Neoplastic; Combined Modality Therapy; Dacarbazine; Disease Progression; Humans; Magnetic Resonance Imaging; Neoplasm Recurrence, Local; Pituitary Gland; Pituitary Hormones; Pituitary Neoplasms; Temozolomide

2014

Other Studies

28 other study(ies) available for dacarbazine and Cell Transformation, Neoplastic

ArticleYear
SNORD47, a box C/D snoRNA, suppresses tumorigenesis in glioblastoma.
    Oncotarget, 2017, Jul-04, Volume: 8, Issue:27

    Topics: Adult; Aged; Animals; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Dacarbazine; Disease Models, Animal; Disease Progression; Drug Resistance, Neoplasm; Female; G2 Phase Cell Cycle Checkpoints; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Glioblastoma; Humans; Kaplan-Meier Estimate; Male; Mice; Middle Aged; Neoplasm Grading; Neoplasm Staging; Prognosis; RNA, Small Nucleolar; Temozolomide; Tumor Burden; Xenograft Model Antitumor Assays

2017
Magnetic core mesoporous silica nanoparticles doped with dacarbazine and labelled with 99mTc for early and differential detection of metastatic melanoma by single photon emission computed tomography.
    Artificial cells, nanomedicine, and biotechnology, 2018, Volume: 46, Issue:sup1

    Topics: Animals; Cell Line, Tumor; Cell Transformation, Neoplastic; Dacarbazine; Diagnosis, Differential; Early Detection of Cancer; Humans; Isotope Labeling; Magnets; Melanoma; Mice; Mice, Inbred BALB C; Nanoparticles; Neoplasm Metastasis; Porosity; Silicon Dioxide; Technetium; Tomography, Emission-Computed, Single-Photon

2018
Molecular analysis of a recurrent glioblastoma treated with bevacizumab.
    Brain tumor pathology, 2014, Volume: 31, Issue:1

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Bevacizumab; Brain Neoplasms; Cell Transformation, Neoplastic; Dacarbazine; Fatal Outcome; Frontal Lobe; Glioblastoma; Humans; Magnetic Resonance Imaging; Male; Matrix Metalloproteinase 14; Matrix Metalloproteinase 2; Middle Aged; Neoplasm Recurrence, Local; Proto-Oncogene Proteins c-akt; Temozolomide; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factor Receptor-2

2014
The human melanoma side population displays molecular and functional characteristics of enriched chemoresistance and tumorigenesis.
    PloS one, 2013, Volume: 8, Issue:10

    Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Dacarbazine; Disease Progression; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Jumonji Domain-Containing Histone Demethylases; Male; Melanoma; Mice; Mice, SCID; Neoplasm Proteins; Neoplasm Staging; Neoplasm Transplantation; Neoplastic Stem Cells; Nuclear Proteins; Repressor Proteins; Side-Population Cells; Skin Neoplasms; Tumor Burden

2013
Clinical course of central neurocytoma with malignant transformation-an indication for craniospinal irradiation.
    Pathology oncology research : POR, 2014, Volume: 20, Issue:2

    Topics: Adult; Brain Neoplasms; Cell Transformation, Neoplastic; Cerebrospinal Fluid; Chemotherapy, Adjuvant; Child, Preschool; Craniospinal Irradiation; Dacarbazine; Female; Humans; Ki-67 Antigen; Magnetic Resonance Imaging; Male; Middle Aged; Neurocytoma; Radiotherapy, Adjuvant; Temozolomide; Young Adult

2014
Conversion of differentiated cancer cells into cancer stem-like cells in a glioblastoma model after primary chemotherapy.
    Cell death and differentiation, 2014, Volume: 21, Issue:7

    Topics: Animals; Antineoplastic Agents, Alkylating; Basic Helix-Loop-Helix Transcription Factors; Brain Neoplasms; Cell Line, Tumor; Cell Transformation, Neoplastic; Dacarbazine; Glioblastoma; Humans; Male; Mice, Nude; Neoplastic Stem Cells; Phenotype; Temozolomide; Xenograft Model Antitumor Assays

2014
miR-125b inhibitor enhance the chemosensitivity of glioblastoma stem cells to temozolomide by targeting Bak1.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2014, Volume: 35, Issue:7

    Topics: Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; Cell Transformation, Neoplastic; Dacarbazine; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; MicroRNAs; Neoplastic Stem Cells; Temozolomide

2014
Triptolide synergistically enhances temozolomide-induced apoptosis and potentiates inhibition of NF-κB signaling in glioma initiating cells.
    The American journal of Chinese medicine, 2014, Volume: 42, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Cell Line, Tumor; Cell Transformation, Neoplastic; Dacarbazine; Disease Models, Animal; Diterpenes; Drug Synergism; Epoxy Compounds; Glioma; Humans; Mice; Neoplasm Transplantation; NF-kappa B; Phenanthrenes; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Stimulation, Chemical; Temozolomide; Transcription, Genetic; X-Linked Inhibitor of Apoptosis Protein

2014
Mutant IDH1-driven cellular transformation increases RAD51-mediated homologous recombination and temozolomide resistance.
    Cancer research, 2014, Sep-01, Volume: 74, Issue:17

    Topics: Cell Line, Tumor; Cell Transformation, Neoplastic; Dacarbazine; DNA Damage; DNA Repair; Drug Resistance, Neoplasm; G2 Phase Cell Cycle Checkpoints; Glioma; Homologous Recombination; Humans; Isocitrate Dehydrogenase; Mutation; Rad51 Recombinase; Temozolomide

2014
Temozolomide increases the number of mismatch repair-deficient intestinal crypts and accelerates tumorigenesis in a mouse model of Lynch syndrome.
    Gastroenterology, 2014, Volume: 147, Issue:5

    Topics: Adenocarcinoma; Adenoma; Animals; Cell Proliferation; Cell Transformation, Neoplastic; Colorectal Neoplasms, Hereditary Nonpolyposis; Dacarbazine; Disease Models, Animal; DNA Mismatch Repair; Female; Intestinal Mucosa; Intestines; Male; Mice, Knockout; MutS Homolog 2 Protein; Neoplastic Stem Cells; Risk Factors; Temozolomide; Time Factors

2014
RRAD promotes EGFR-mediated STAT3 activation and induces temozolomide resistance of malignant glioblastoma.
    Molecular cancer therapeutics, 2014, Volume: 13, Issue:12

    Topics: Antineoplastic Agents, Alkylating; Cell Line, Tumor; Cell Nucleus; Cell Transformation, Neoplastic; Dacarbazine; Drug Resistance, Neoplasm; Endosomes; ErbB Receptors; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Prognosis; Protein Stability; Protein Transport; ras Proteins; Spheroids, Cellular; STAT3 Transcription Factor; Temozolomide; Tumor Cells, Cultured

2014
Mutational analysis reveals the origin and therapy-driven evolution of recurrent glioma.
    Neurosurgery, 2014, Volume: 75, Issue:6

    Topics: Antineoplastic Agents; Brain Neoplasms; Cell Transformation, Neoplastic; Dacarbazine; Glioma; Humans; Mutation; Neoplasm Recurrence, Local; Temozolomide

2014
Skin cancer. Golden age of melanoma therapy.
    Nature reviews. Clinical oncology, 2015, Volume: 12, Issue:1

    Topics: Antibodies, Monoclonal; Antineoplastic Agents; Cell Transformation, Neoplastic; Dacarbazine; Female; Humans; Male; Melanoma; Programmed Cell Death 1 Receptor; Proto-Oncogene Proteins B-raf

2015
Epigenetic targeting of glioma stem cells: Short-term and long-term treatments with valproic acid modulate DNA methylation and differentiation behavior, but not temozolomide sensitivity.
    Oncology reports, 2016, Volume: 35, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Cell Line, Tumor; Cell Shape; Cell Survival; Cell Transformation, Neoplastic; Dacarbazine; DNA Methylation; Drug Resistance, Neoplasm; Drug Synergism; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Glioblastoma; Histone Deacetylase Inhibitors; Humans; Neoplastic Stem Cells; Promoter Regions, Genetic; Temozolomide; Valproic Acid

2016
Malignant transformation of low-grade gliomas in patients undergoing adjuvant therapy.
    Acta neurologica Belgica, 2017, Volume: 117, Issue:1

    Topics: Adult; Antineoplastic Agents; Brain Neoplasms; Cell Transformation, Neoplastic; Chemoradiotherapy, Adjuvant; Dacarbazine; Female; Glioma; Humans; Male; Middle Aged; Radiotherapy; Temozolomide

2017
Recurrent metastatic neuroblastoma followed by myelodysplastic syndrome: possible leukemogenic role of temozolomide.
    Pediatric blood & cancer, 2008, Volume: 51, Issue:4

    Topics: Adolescent; Adult; Cell Transformation, Neoplastic; Child; Combined Modality Therapy; Dacarbazine; Female; Humans; Myelodysplastic Syndromes; Neoplasm Metastasis; Neuroblastoma; Recurrence; Temozolomide

2008
Malignant transformation of an optic pathway glioma without prior radiation therapy.
    Journal of neurosurgery. Pediatrics, 2010, Volume: 5, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Cell Transformation, Neoplastic; Chemotherapy, Adjuvant; Child, Preschool; Combined Modality Therapy; Cranial Irradiation; Craniotomy; Dacarbazine; Fatal Outcome; Humans; Hypothalamus; Magnetic Resonance Imaging; Male; Neoplasms, Radiation-Induced; Optic Chiasm; Optic Nerve; Optic Nerve Glioma; Radiotherapy, Adjuvant; Temozolomide

2010
A mechanism of acquiring temozolomide resistance during transformation of atypical prolactinoma into prolactin-producing pituitary carcinoma: case report.
    Neurosurgery, 2011, Volume: 68, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Carcinoma; Cell Transformation, Neoplastic; Dacarbazine; DNA Modification Methylases; DNA Repair Enzymes; DNA-Binding Proteins; Drug Resistance, Neoplasm; Fatal Outcome; Female; Humans; Immunohistochemistry; Middle Aged; Mutation; Pituitary Neoplasms; Prolactin; Prolactinoma; Temozolomide; Tumor Suppressor Protein p53; Tumor Suppressor Proteins

2011
Radiation-induced astrocytoma with rapid malignant transformation: case report.
    Neurologia medico-chirurgica, 2011, Volume: 51, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Astrocytoma; Basal Ganglia; Brain Neoplasms; Cell Transformation, Neoplastic; Cerebellar Neoplasms; Dacarbazine; Fatal Outcome; Gait Disorders, Neurologic; Humans; Hydrocephalus; Male; Neoplasms, Germ Cell and Embryonal; Neoplasms, Radiation-Induced; Neoplasms, Second Primary; Temozolomide; Time Factors; Young Adult

2011
Inhibition of cancer stem cell-like properties and reduced chemoradioresistance of glioblastoma using microRNA145 with cationic polyurethane-short branch PEI.
    Biomaterials, 2012, Volume: 33, Issue:5

    Topics: 3' Untranslated Regions; Aged; Base Sequence; Cell Transformation, Neoplastic; Dacarbazine; Down-Regulation; Drug Resistance, Neoplasm; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Transfer Techniques; Glioblastoma; Humans; Male; MicroRNAs; Middle Aged; Molecular Sequence Data; Neoplastic Stem Cells; Octamer Transcription Factor-3; Polyethyleneimine; Polyurethanes; Radiation Tolerance; SOXB1 Transcription Factors; Temozolomide

2012
ALDH1A isozymes are markers of human melanoma stem cells and potential therapeutic targets.
    Stem cells (Dayton, Ohio), 2012, Volume: 30, Issue:10

    Topics: Aldehyde Dehydrogenase; Aldehyde Dehydrogenase 1 Family; Aldehyde Oxidoreductases; Animals; Apoptosis; Cell Transformation, Neoplastic; Dacarbazine; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Isoenzymes; Melanoma; Mice; Mice, Inbred NOD; Mice, SCID; Neoplasm Transplantation; Neoplastic Stem Cells; Response Elements; Retinal Dehydrogenase; RNA, Small Interfering; Skin Neoplasms; Temozolomide; Tretinoin

2012
Multimodal magnetic resonance imaging and 18F-L-dihydroxyphenylalanine positron emission tomography in early characterization of pseudoresponse and nonenhancing tumor progression in a pediatric patient with malignant transformation of ganglioglioma treate
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Jan-01, Volume: 31, Issue:1

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Cell Transformation, Neoplastic; Child, Preschool; Dacarbazine; Dihydroxyphenylalanine; Disease Progression; Female; Fluorine Radioisotopes; Ganglioglioma; Humans; Magnetic Resonance Imaging; Positron-Emission Tomography; Prognosis; Radiopharmaceuticals; Temozolomide

2013
Generation of an immortalized human endothelial cell line as a model of neovascular proliferating endothelial cells to assess chemosensitivity to anticancer drugs.
    International journal of oncology, 2005, Volume: 27, Issue:2

    Topics: Animals; Antigens, CD; Antigens, Neoplasm; Antigens, Polyomavirus Transforming; Antineoplastic Agents, Alkylating; Blotting, Western; Cell Line; Cell Line, Transformed; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Dacarbazine; DNA-Binding Proteins; Endothelial Cells; Flow Cytometry; Gene Expression; HT29 Cells; Humans; Male; Membrane Proteins; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Proteins; Neoplasms, Experimental; Plasmids; Platelet Endothelial Cell Adhesion Molecule-1; Reverse Transcriptase Polymerase Chain Reaction; Telomerase; Telomere; Temozolomide; Transfection; Transplantation, Heterologous; Tumor Stem Cell Assay; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factor Receptor-2; von Willebrand Factor

2005
DNA cross-linking and cytotoxicity in normal and transformed human cells treated in vitro with 8-carbamoyl-3-(2-chloroethyl)imidazo[5,1-d] -1,2,3,5-tetrazin-4(3H)-one.
    Cancer research, 1984, Volume: 44, Issue:5

    Topics: Cell Division; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Dacarbazine; DNA; Embryo, Mammalian; Humans; Imidazoles; Kinetics; Nitrogen Mustard Compounds

1984
Malignant degeneration in leiomyomatosis peritonealis disseminata.
    Gynecologic oncology, 1996, Volume: 61, Issue:2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cell Transformation, Neoplastic; Dacarbazine; Epirubicin; Female; Humans; Ifosfamide; Leiomyomatosis; Middle Aged; Peritoneal Neoplasms

1996
Composite prolymphocytoid and hodgkin transformation of chronic lymphocytic leukemia.
    Archives of pathology & laboratory medicine, 2000, Volume: 124, Issue:6

    Topics: Aged; Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cell Transformation, Neoplastic; Dacarbazine; Doxorubicin; Fatal Outcome; Hodgkin Disease; Humans; Immunophenotyping; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Reed-Sternberg Cells; Vinblastine

2000
Transformation of Hodgkin's disease to high-grade B-cell lymphoma: remission after Rituximab monotherapy.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2001, Volume: 12, Issue:8

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cell Transformation, Neoplastic; Cyclophosphamide; Dacarbazine; Doxorubicin; Drug Resistance, Neoplasm; Female; Hodgkin Disease; Humans; Lymphoma, B-Cell; Lymphoma, Non-Hodgkin; Middle Aged; Neoplasm Staging; Neoplasms, Second Primary; Prednisone; Procarbazine; Remission Induction; Rituximab; Vinblastine; Vincristine

2001
Inhibition of melanoma growth and metastasis by combination with (-)-epigallocatechin-3-gallate and dacarbazine in mice.
    Journal of cellular biochemistry, 2001, Volume: 83, Issue:4

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Catechin; Cell Aggregation; Cell Communication; Cell Movement; Cell Transformation, Neoplastic; Dacarbazine; Drug Screening Assays, Antitumor; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Growth Inhibitors; Injections, Intraperitoneal; Lung Neoplasms; Male; Matrix Metalloproteinases; Melanoma, Experimental; Mice; Neoplasm Transplantation; Phosphorylation; Protein-Tyrosine Kinases; Survival Rate; Tea; Tumor Cells, Cultured; Tumor Stem Cell Assay; Tyrosine

2001