dacarbazine and Carcinoma, Non-Small Cell Lung

dacarbazine has been researched along with Carcinoma, Non-Small Cell Lung in 42 studies

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.38)18.7374
1990's1 (2.38)18.2507
2000's18 (42.86)29.6817
2010's22 (52.38)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Luo, Y; Tang, J; Tian, J; Xiang, J1
Grossman, S; Mehta, M; O'Neill, A; Robins, HI1
Sperduto, PW1
Altorjai, G; Dieckmann, K; Geissler, K; Hassler, MR; Knocke-Abulesz, TH; Marosi, C; Pfeifer, W1
Abrams, JS; Conley, BA; Freidlin, B; Korn, EL; McShane, LM; Polley, MY1
Iversen, TZ1
Bozzao, A; De Sanctis, V; Enrici, RM; Lanzetta, G; Minniti, G; Osti, M; Romano, A; Scaringi, C; Valeriani, M1
Jiang, Z; Leng, C; Liang, S; Liu, H; Lu, F; Lu, S; Qi, X; Shi, J; Wang, Q; Wang, S1
Berkowitz, MJ; Boggs, DH; Langer, CJ; Mehta, MP; Robins, HI; Traynor, AM1
Andersen, MH; Iversen, TZ; Svane, IM1
Chen, TC; Song, X; Wang, W; Wang, X; Xie, L; Zeng, Q1
Chatziioannou, A; Kolisis, F; Koryllou, A; Moulos, P; Papadodima, O; Piroti, G; Pletsa, V1
Hiddinga, BI; Janssens, A; Pauwels, P; van Meerbeeck, JP1
Chen, H; Deng, X; Fei, S; Fei, Z; Jin, X; Lin, B; Su, H; Xie, CY; Zhao, L; Zheng, Z1
Addeo, R; Caraglia, M; Cennamo, G; De Rosa, C; Del Prete, S; Faiola, V; Guarrasi, R; Leo, L; Montella, L; Vincenzi, B1
Georgoulias, V; Giassas, S; Kalbakis, K; Kalykaki, A; Kentepozidis, N; Kotsakis, A; Kouroussis, C; Saridaki, Z; Vamvakas, L; Vardakis, N1
Adema, AD; Honeywell, RJ; Peters, GJ; van der Born, K1
Bajetta, E; Cascinu, S; Crinò, L; Danova, M; Del Prete, S; Salvagni, S; Schiavetto, I; Siena, S; Vitali, M1
Chouaid, C; Chua, D; Curran, W; Gottfried, M; Krzakowski, M; Martinez, JI; Pallotta, MG; Throuvalas, N1
Bang, SM; Chung, JH; Kim, JH; Kim, YJ; Lee, JS; Lee, KW1
Anchisi, S; Bernhard, J; Bodis, S; Caspar, CB; Cathomas, R; D'Addario, G; Fischer, N; Klingbiel, D; Kotrubczik, NM; Mayer, M; Pesce, GA; Peters, S; Pilop, C; Pless, M; Ribi, K; Schlaeppi, M; Stupp, R; von Moos, R; Weber, DC; Zouhair, A1
Li, HQ; Liu, ZF; Tao, RJ1
Balañá, C; Bruna, J; Chacón, I; Gil, M; Langa, JM; Martín, M; Segura, PP1
Bi, ZF; He, Y; Liao, K; Liu, YM1
Buyyounouski, MK; Demas, W; Khuntia, D; Komaki, R; Mehta, MP; Nedzi, LA; Perry, G; Robins, HI; Schell, MC; Shah, SA; Souhami, L; Sperduto, PW; Suh, JH; Wang, M; Werner-Wasik, M1
Ebert, BL; Niemierko, E; Salgia, R; Shaffer, K1
Ardizzoni, A; Debruyne, C; Dziadziuszko, R; Giaccone, G; Legrand, C; Postmus, PE; Price, A; Smit, EF1
Almassy, R; Barton, S; Batey, MA; Calabrese, CR; Calvert, AH; Canan-Koch, S; Curtin, NJ; Durkacz, BW; Hostomsky, Z; Kumpf, RA; Kyle, S; Li, J; Maegley, K; Newell, DR; Notarianni, E; Skalitzky, D; Stratford, IJ; Thomas, HD; Wang, LZ; Webber, SE; Williams, KJ1
Langer, CJ; Somer, RA1
Blanco, G; Bordonaro, R; Castorina, S; Failla, G; Giorgio, CG; Giuffrida, D; Pappalardo, A; Russo, A; Salice, P; Santini, D1
Narita, Y1
Abrey, LE; Demopoulos, A; Malkin, MG; Omuro, AM; Raizer, JJ1
Berard, H; Bombaron, P; Breton, JL; Chavaillon, JM; Corre, R; Cortot, AB; Falchero, L; Gerinière, L; Gimenez, C; Mercier, C; Perol, M; Robinet, G; Souquet, PJ1
Choong, NW; Hoffman, PC; Kozloff, M; Mauer, AM; Rudin, CM; Sciortino, DF; Szeto, L; Villano, JL; Vokes, EE; Wade, JL; Winegarden, JD1
Mehta, M; Robins, HI; Traynor, AM1
Weller, M1
Balafouta, MJ; Kolokouris, D; Kouloulias, VE; Kouvaris, JR; Miliadou, A; Papacharalampous, XN; Vlahos, LJ1
Cloud, GA; Fiveash, JB; Guthrie, BL; Markert, JM; Meredith, RF; Nordal, RA; Sawrie, SM; Spencer, SA1
Abrey, LE; Christodoulou, C1
Abrey, LE; Boutros, DY; Mack, M; Malkin, MG; Olson, JD; Raizer, JJ; Rodavitch, A1
Boaziz, C1
Engelhardt, R1

Reviews

8 review(s) available for dacarbazine and Carcinoma, Non-Small Cell Lung

ArticleYear
Combined treatment for non-small cell lung cancer and breast cancer patients with brain metastases with whole brain radiotherapy and temozolomide: a systematic review and meta-analysis.
    Journal of neuro-oncology, 2017, Volume: 135, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Chemoradiotherapy; Dacarbazine; Humans; Lung Neoplasms; Randomized Controlled Trials as Topic; Temozolomide

2017
Immune modulations during chemoimmunotherapy & novel vaccine strategies--in metastatic melanoma and non small-cell lung cancer.
    Danish medical journal, 2013, Volume: 60, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cancer Vaccines; Carcinoma, Non-Small-Cell Lung; Dacarbazine; Epitopes; Humans; Immunotherapy; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inhibitor of Apoptosis Proteins; Interferon alpha-2; Interferon-alpha; Interleukin-2; Lung Neoplasms; Lymphocyte Count; Lymphocytosis; Melanoma; Recombinant Proteins; Survivin; T-Lymphocytes; Temozolomide

2013
The targeting of indoleamine 2,3 dioxygenase -mediated immune escape in cancer.
    Basic & clinical pharmacology & toxicology, 2015, Volume: 116, Issue:1

    Topics: Antibodies, Monoclonal; Carcinoma, Non-Small-Cell Lung; Dacarbazine; Humans; Immunologic Factors; Immunotherapy; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon alpha-2; Interferon-alpha; Interleukin-2; Ipilimumab; Lung Neoplasms; Male; Melanoma; Prostatic Neoplasms; Recombinant Proteins; Temozolomide; Tissue Extracts

2015
O
    Lung cancer (Amsterdam, Netherlands), 2017, Volume: 107

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carcinogenesis; Carcinoma, Non-Small-Cell Lung; Dacarbazine; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Epigenomics; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Neuroendocrine Tumors; O(6)-Methylguanine-DNA Methyltransferase; Predictive Value of Tests; Prognosis; Promoter Regions, Genetic; Small Cell Lung Carcinoma; Temozolomide; Treatment Outcome; Tumor Suppressor Proteins

2017
[Whole brain radiation therapy plus temozolomide in the treatment of brain metastases from non small cell lung cancer: a meta-analysis].
    Zhonghua yi xue za zhi, 2012, Dec-04, Volume: 92, Issue:45

    Topics: Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Combined Modality Therapy; Cranial Irradiation; Dacarbazine; Humans; Randomized Controlled Trials as Topic; Temozolomide

2012
[Chemotherapy for brain metastases].
    Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63 Suppl 9

    Topics: Anticonvulsants; Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barrier; Brain Neoplasms; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Dacarbazine; Dementia, Vascular; Humans; Lung Neoplasms; Melanoma; Metalloporphyrins; Prednisolone; Radiation-Sensitizing Agents; Radiotherapy, Adjuvant; Temozolomide

2005
Temozolomide for treating brain metastases.
    Seminars in oncology, 2001, Volume: 28, Issue:4 Suppl 13

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Chemotherapy, Adjuvant; Clinical Trials as Topic; Dacarbazine; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Temozolomide; Whole-Body Irradiation

2001
[Contribution of a new nitrosourea compound: fotemustine].
    Pathologie-biologie, 1992, Volume: 40, Issue:9 Pt 2

    Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cisplatin; Dacarbazine; Drug Therapy, Combination; Humans; Liver Neoplasms; Lung Neoplasms; Melanoma; Nitrosourea Compounds; Organophosphorus Compounds

1992

Trials

17 trial(s) available for dacarbazine and Carcinoma, Non-Small Cell Lung

ArticleYear
Temozolomide added to whole brain radiotherapy in patients with multiple brain metastases of non-small-cell lung cancer: a multicentric Austrian phase II study.
    Wiener klinische Wochenschrift, 2013, Volume: 125, Issue:15-16

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Austria; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Chemoradiotherapy; Dacarbazine; Feasibility Studies; Female; Humans; Lung Neoplasms; Male; Middle Aged; Radiation Injuries; Temozolomide; Treatment Outcome

2013
Whole brain reirradiation and concurrent temozolomide in patients with brain metastases.
    Journal of neuro-oncology, 2014, Volume: 118, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Breast Neoplasms; Carcinoma; Carcinoma, Non-Small-Cell Lung; Chemoradiotherapy; Cranial Irradiation; Dacarbazine; Disease Progression; Female; Humans; Lung Neoplasms; Male; Middle Aged; Prognosis; Prospective Studies; Retreatment; Retrospective Studies; Temozolomide; Treatment Outcome

2014
Strategies to prevent brain metastasis in high-risk non-small-cell lung cancer: lessons learned from a randomized study of maintenance temozolomide versus observation.
    Clinical lung cancer, 2014, Volume: 15, Issue:6

    Topics: Aged; Brain; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Dacarbazine; Early Termination of Clinical Trials; Female; Humans; Lung Neoplasms; Maintenance Chemotherapy; Male; Middle Aged; Neoplasm Staging; Radiography; Risk; Survival Analysis; Temozolomide

2014
Phase 2 trial of temozolomide using protracted low-dose and whole-brain radiotherapy for nonsmall cell lung cancer and breast cancer patients with brain metastases.
    Cancer, 2008, Nov-01, Volume: 113, Issue:9

    Topics: Aged; Antineoplastic Agents, Alkylating; Bone Marrow; Brain Neoplasms; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Combined Modality Therapy; Cranial Irradiation; Dacarbazine; Female; Humans; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Prognosis; Remission Induction; Survival Rate; Temozolomide

2008
Continuous administration of daily low-dose temozolomide in pretreated patients with advanced non-small cell lung cancer: a phase II study.
    Oncology, 2009, Volume: 76, Issue:2

    Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Dacarbazine; Drug Administration Schedule; Female; Humans; Lung Neoplasms; Male; Middle Aged; Salvage Therapy; Temozolomide; Time Factors; Treatment Outcome; Triazines

2009
Dose-dense temozolomide regimen for the treatment of brain metastases from melanoma, breast cancer, or lung cancer not amenable to surgery or radiosurgery: a multicenter phase II study.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2010, Volume: 21, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Dacarbazine; Drug Resistance, Neoplasm; Female; Humans; Lung Neoplasms; Male; Maximum Tolerated Dose; Melanoma; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Palliative Care; Prospective Studies; Remission Induction; Salvage Therapy; Survival Rate; Temozolomide; Treatment Outcome

2010
Whole-brain radiation therapy plus concomitant temozolomide for the treatment of brain metastases from non-small-cell lung cancer: a randomized, open-label phase II study.
    Clinical lung cancer, 2010, Volume: 11, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Combined Modality Therapy; Cranial Irradiation; Dacarbazine; Female; Humans; Kaplan-Meier Estimate; Lung Neoplasms; Male; Middle Aged; Temozolomide; Treatment Outcome

2010
Outcome, quality of life and cognitive function of patients with brain metastases from non-small cell lung cancer treated with whole brain radiotherapy combined with gefitinib or temozolomide. A randomised phase II trial of the Swiss Group for Clinical Ca
    European journal of cancer (Oxford, England : 1990), 2012, Volume: 48, Issue:3

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Brain Neoplasms; Brief Psychiatric Rating Scale; Carcinoma, Non-Small-Cell Lung; Chemoradiotherapy; Cognition; Cranial Irradiation; Dacarbazine; Female; Gefitinib; Humans; Lung Neoplasms; Male; Middle Aged; Outcome Assessment, Health Care; Quality of Life; Quinazolines; Survival Analysis; Temozolomide

2012
Phase II trial of temozolomide for leptomeningeal metastases in patients with solid tumors.
    Journal of neuro-oncology, 2012, Volume: 109, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Dacarbazine; Female; Follow-Up Studies; Humans; Lung Neoplasms; Magnetic Resonance Imaging; Male; Melanoma; Meningeal Neoplasms; Middle Aged; Neoplasm Staging; Prognosis; Prospective Studies; Survival Rate; Temozolomide

2012
A phase 3 trial of whole brain radiation therapy and stereotactic radiosurgery alone versus WBRT and SRS with temozolomide or erlotinib for non-small cell lung cancer and 1 to 3 brain metastases: Radiation Therapy Oncology Group 0320.
    International journal of radiation oncology, biology, physics, 2013, Apr-01, Volume: 85, Issue:5

    Topics: Aged; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Combined Modality Therapy; Cranial Irradiation; Dacarbazine; Erlotinib Hydrochloride; Humans; Lung Neoplasms; Middle Aged; Protein Kinase Inhibitors; Quinazolines; Radiosurgery; Radiotherapy Dosage; Temozolomide

2013
Temozolomide in patients with advanced non-small cell lung cancer with and without brain metastases. a phase II study of the EORTC Lung Cancer Group (08965).
    European journal of cancer (Oxford, England : 1990), 2003, Volume: 39, Issue:9

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Dacarbazine; Female; Humans; Lung Neoplasms; Male; Middle Aged; Temozolomide; Treatment Outcome

2003
Oral temozolomide in heavily pre-treated brain metastases from non-small cell lung cancer: phase II study.
    Lung cancer (Amsterdam, Netherlands), 2005, Volume: 50, Issue:2

    Topics: Administration, Oral; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Dacarbazine; Female; Humans; Lung Neoplasms; Male; Middle Aged; Palliative Care; Temozolomide; Treatment Outcome

2005
Vinorelbine combined with a protracted course of temozolomide for recurrent brain metastases: a phase I trial.
    Journal of neuro-oncology, 2006, Volume: 78, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Dacarbazine; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Lung Neoplasms; Lymphopenia; Male; Maximum Tolerated Dose; Middle Aged; Neutropenia; Temozolomide; Thrombocytopenia; Treatment Outcome; Vinblastine; Vinorelbine

2006
Phase II trial of temozolomide and cisplatin followed by whole brain radiotherapy in non-small-cell lung cancer patients with brain metastases: a GLOT-GFPC study.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2006, Volume: 17, Issue:9

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Cisplatin; Dacarbazine; Female; Humans; Lung Neoplasms; Male; Middle Aged; Temozolomide; Treatment Outcome

2006
Phase II trial of temozolomide and irinotecan as second-line treatment for advanced non-small cell lung cancer.
    Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2006, Volume: 1, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Camptothecin; Carcinoma, Non-Small-Cell Lung; Dacarbazine; Disease-Free Survival; Female; Humans; Irinotecan; Lung Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Survival Analysis; Temozolomide

2006
Phase II study of temozolomide and concomitant whole-brain radiotherapy in patients with brain metastases from solid tumors.
    Onkologie, 2007, Volume: 30, Issue:7

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Chemotherapy, Adjuvant; Clinical Trials, Phase II as Topic; Combined Modality Therapy; Cranial Irradiation; Dacarbazine; Female; Humans; Lung Neoplasms; Male; Melanoma; Middle Aged; Mouth Neoplasms; Neoplasms, Unknown Primary; Palliative Care; Rectal Neoplasms; Research Design; Temozolomide; Treatment Outcome

2007
A phase II trial of temozolomide for patients with recurrent or progressive brain metastases.
    Journal of neuro-oncology, 2001, Volume: 53, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Dacarbazine; Disease Progression; Female; Humans; Lung Neoplasms; Magnetic Resonance Imaging; Male; Middle Aged; Neoplasm Recurrence, Local; Survival Analysis; Temozolomide; Tomography, X-Ray Computed

2001

Other Studies

17 other study(ies) available for dacarbazine and Carcinoma, Non-Small Cell Lung

ArticleYear
A phase 3 trial of whole brain radiation therapy and stereotactic radiosurgery alone versus WBRT & SRS with temozolomide or erlotinib for non-small cell lung cancer and 1 to 3 brain metastases: Radiation Therapy Oncology Group 0320: in regard to Sperduto
    International journal of radiation oncology, biology, physics, 2013, Aug-01, Volume: 86, Issue:5

    Topics: Antineoplastic Agents; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Cranial Irradiation; Dacarbazine; Humans; Lung Neoplasms; Quinazolines; Radiosurgery

2013
In reply to Robins et al.
    International journal of radiation oncology, biology, physics, 2013, Aug-01, Volume: 86, Issue:5

    Topics: Antineoplastic Agents; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Cranial Irradiation; Dacarbazine; Humans; Lung Neoplasms; Quinazolines; Radiosurgery

2013
Statistical and practical considerations for clinical evaluation of predictive biomarkers.
    Journal of the National Cancer Institute, 2013, Nov-20, Volume: 105, Issue:22

    Topics: Antineoplastic Agents; Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Dacarbazine; DNA Modification Methylases; DNA Repair Enzymes; ErbB Receptors; Gefitinib; Glioblastoma; Humans; Indazoles; Interleukin-6; Kidney Neoplasms; Lung Neoplasms; Methylation; Molecular Targeted Therapy; Mutation; Neoplasms; Precision Medicine; Predictive Value of Tests; Pyrimidines; Quinazolines; Radiotherapy, Adjuvant; Randomized Controlled Trials as Topic; Sample Size; Sulfonamides; Temozolomide; Tumor Suppressor Proteins

2013
Whole brain radiation therapy followed by intensity-modulated boosting treatment combined with concomitant temozolomide for brain metastases from non-small-cell lung cancer.
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2014, Volume: 16, Issue:11

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Combined Modality Therapy; Cranial Irradiation; Dacarbazine; Disease-Free Survival; Female; Humans; Kaplan-Meier Estimate; Lung Neoplasms; Male; Middle Aged; Proportional Hazards Models; Radiotherapy, Intensity-Modulated; Retrospective Studies; Temozolomide

2014
Temozolomide-perillyl alcohol conjugate induced reactive oxygen species accumulation contributes to its cytotoxicity against non-small cell lung cancer.
    Scientific reports, 2016, Mar-07, Volume: 6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dacarbazine; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; MAP Kinase Signaling System; Membrane Potential, Mitochondrial; Monoterpenes; Reactive Oxygen Species; Temozolomide

2016
Modulation of Pathways Underlying Distinct Cell Death Mechanisms in Two Human Lung Cancer Cell Lines in Response to SN1 Methylating Agents Treatment.
    PloS one, 2016, Volume: 11, Issue:7

    Topics: A549 Cells; Alkylating Agents; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Cell Death; Cell Line, Tumor; Dacarbazine; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Ontology; Humans; Lung Neoplasms; Methylnitrosourea; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Temozolomide

2016
The efficacy and roles of combining temozolomide with whole brain radiotherapy in protection neurocognitive function and improvement quality of life of non-small-cell lung cancer patients with brain metastases.
    BMC cancer, 2017, 01-10, Volume: 17, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Chemoradiotherapy; Cranial Irradiation; Dacarbazine; Female; Follow-Up Studies; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Neurocognitive Disorders; Prognosis; Quality of Life; Retrospective Studies; Survival Rate; Temozolomide

2017
Cell cycle effects and increased adduct formation by temozolomide enhance the effect of cytotoxic and targeted agents in lung cancer cell lines.
    Journal of chemotherapy (Florence, Italy), 2009, Volume: 21, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Line, Tumor; Dacarbazine; Deoxycytidine; Deoxyguanosine; DNA Adducts; DNA Methylation; Drug Synergism; Gemcitabine; Humans; Lung Neoplasms; Mice; O(6)-Methylguanine-DNA Methyltransferase; Paclitaxel; Piperidines; Pyridines; Temozolomide

2009
Two consecutive cases of platinum-refractory pulmonary pleomorphic carcinoma that showed dramatic responses to MAID (mesna, doxorubicin, ifosfamide and dacarbazine) chemotherapy.
    Japanese journal of clinical oncology, 2011, Volume: 41, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Dacarbazine; Doxorubicin; Drug Resistance, Neoplasm; Female; Humans; Ifosfamide; Lung Neoplasms; Male; Mesna; Middle Aged; Organoplatinum Compounds; Salvage Therapy; Survival Rate; Treatment Outcome

2011
[Protracted low-dose temozolomide combined with concomitant whole brain radiotherapy for brain metastases from non-small cell lung cancer].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2011, Volume: 33, Issue:10

    Topics: Adult; Aged; Agranulocytosis; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Chemoradiotherapy; Dacarbazine; Disease-Free Survival; Dose-Response Relationship, Drug; Female; Humans; Lung Neoplasms; Male; Middle Aged; Remission Induction; Survival Rate; Temozolomide; Vomiting

2011
Use of temozolomide with other cytotoxic chemotherapy in the treatment of patients with recurrent brain metastases from lung cancer.
    The oncologist, 2003, Volume: 8, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Combined Modality Therapy; Dacarbazine; Etoposide; Female; Humans; Lung Neoplasms; Middle Aged; Prognosis; Temozolomide; Treatment Outcome

2003
Anticancer chemosensitization and radiosensitization by the novel poly(ADP-ribose) polymerase-1 inhibitor AG14361.
    Journal of the National Cancer Institute, 2004, Jan-07, Volume: 96, Issue:1

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Azulenes; Benzodiazepines; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Colorectal Neoplasms; Dacarbazine; Drug Resistance, Neoplasm; Enzyme Inhibitors; Gamma Rays; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Mice; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Radiation-Sensitizing Agents; Temozolomide; Transplantation, Heterologous

2004
Response to temozolomide in second-line treatment of recurrent nonsmall cell lung carcinoma: case report.
    Cancer investigation, 2005, Volume: 23, Issue:2

    Topics: Administration, Oral; Antineoplastic Agents, Alkylating; Carcinoma, Non-Small-Cell Lung; Dacarbazine; Disease Progression; Drug Resistance, Neoplasm; Fatal Outcome; Female; Humans; Lung Neoplasms; Middle Aged; Neoplasm Recurrence, Local; Temozolomide; Treatment Outcome

2005
Temozolomide as prophylaxis for brain metastasis in non-small cell lung cancer.
    Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2006, Volume: 1, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Camptothecin; Carcinoma, Non-Small-Cell Lung; Dacarbazine; Humans; Irinotecan; Lung Neoplasms; Temozolomide

2006
Radiochemotherapy for brain metastasis: how to define a role for temozolomide.
    Onkologie, 2007, Volume: 30, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Chemotherapy, Adjuvant; Clinical Trials, Phase II as Topic; Cranial Irradiation; Dacarbazine; Humans; Lung Neoplasms; Melanoma; Mouth Neoplasms; Neoplasms, Unknown Primary; Rectal Neoplasms; Research Design; Temozolomide; Treatment Outcome

2007
Predictors of distant brain recurrence for patients with newly diagnosed brain metastases treated with stereotactic radiosurgery alone.
    International journal of radiation oncology, biology, physics, 2008, Jan-01, Volume: 70, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Dacarbazine; Female; Humans; Lung Neoplasms; Male; Melanoma; Middle Aged; Multivariate Analysis; Proportional Hazards Models; Radiosurgery; Retrospective Studies; Temozolomide

2008
Summary of recent clinical experience in whole-body hyperthermia combined with chemotherapy.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1988, Volume: 107

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Dacarbazine; Doxorubicin; Etoposide; Evaluation Studies as Topic; Female; Humans; Hyperthermia, Induced; Lung Neoplasms; Male; Melanoma; Vincristine; Vindesine

1988