dacarbazine and B16 Melanoma

dacarbazine has been researched along with B16 Melanoma in 67 studies

Research

Studies (67)

TimeframeStudies, this research(%)All Research%
pre-19901 (1.49)18.7374
1990's8 (11.94)18.2507
2000's20 (29.85)29.6817
2010's33 (49.25)24.3611
2020's5 (7.46)2.80

Authors

AuthorsStudies
Bhardwaj, A; Fei, Y; Huang, Z; Kaur, J; Knaus, EE; Wu, J; Yuan, H; Zhang, Y; Zou, Y1
Cecchini, AL; Cecchini, R; da Silva Brito, WA; Lopes, NMD; Luiz, RC; Marinello, PC; Sanches, LJ1
Brusco, I; Camponogara, C; Chiepe, KB; da Silva Brum, E; de Almeida, AS; de Andrade, VM; de David Antoniazzi, CT; De Logu, F; Ferreira, J; Geppetti, P; Li Puma, S; Nassini, R; Oliveira, SM; Silva, CR; Trevisan, G1
Li, L; Qian, Z; Qiu, L; Zhang, H; Zhao, P; Zhou, S1
Da-Costa-Rocha, I; Prieto, JM1
Amakye, WK; Liu, H; Ren, J1
Amson, R; Appel, MH; Basílio, AB; Boia-Ferreira, M; Chaim, OM; Da Costa, CRV; Hamasaki, AE; Matsubara, FH; Senff-Ribeiro, A; Telerman, A; Veiga, SS1
Aiba, S; Fujimura, T; Furudate, S; Kakizaki, A; Kambayashi, Y; Lyu, C; Sato, Y; Tanita, K1
Hafeez, A; Kazmi, I1
Caruntu, C; Constantin, C; Neagu, M; Surcel, M; Zurac, S1
Annovazzi, L; Battaglia, L; Biasibetti, E; Boggio, E; Cangemi, L; Capucchio, MT; Clemente, N; Dianzani, C; Dianzani, U; Ferrara, B; Gigliotti, CL; Mellai, M; Miglio, G; Muntoni, E; Schiffer, D1
Cui, H; Huang, W; Li, X; Liao, X; Liu, X; Min, L; Shi, B; Sun, X; Xu, S; Yang, J; Zhang, M; Zheng, H; Zhu, Z1
Banerjee, S; Bhattacharyya, S; Biswas, N; Majumder, B; Mitra, D; Murmu, N; Mustafi, SM; Ray, S1
Ali, N; Banerjee, I; Bharti, R; Chakrabarti, P; Chattopadhyay, S; De, M; Dey, G; Kundu, SC; Mandal, M; Reis, RL1
Imano, M; Kawashima, K; Nishida, S; Obata, N; Satou, T; Tabata, M; Takeda, T; Tsubaki, M1
Choi, YW; Kim, J; Lee, M; Lee, O; Oh, C; Park, G1
Iannone, R; Maiolino, P; Miele, L; Morello, S; Pinto, A1
Castioni, N; Elia, G; Neri, D; Pretto, F1
Amatulli, M; Balderes, P; Brennan, L; Burtrum, D; Credille, KM; Damoci, CB; DeLigio, JT; Duignan, IJ; Kotanides, H; Lebron, MB; Loizos, N; O'Mahony, M; Paz, K; Persaud, K; Prewett, MC; Schwartz, KD; Starodubtseva, M; Surguladze, D; Zhang, Y1
Fietkau, R; Frey, B; Gaipl, US; Werthmöller, N; Wunderlich, R1
Basseville, A; Levine, M; Parrow, NL; Serrano, OK; Violet, PC; Yang, J; Zornjak, J1
Imamura, R; Itoh, T; Kawada, A; Kawai, S; Koyama, A; Matsuo, K; Nakayama, T; Nishiwaki, K; Oiso, N; Yoshie, O1
Fortunato, RS; Kajitani, GS; Menck, CF; Quinet, A; Rocha, CR1
Bontcheva-Diaz, V; Bouska, JJ; Donawho, CK; Frost, DJ; Fry, EH; Gandhi, VB; Giranda, VL; Gong, J; Grandel, R; Johnson, EF; Klinghofer, V; Liu, X; Lubisch, W; Luo, Y; Marsh, KC; Olson, AM; Park, CH; Penning, TD; Rosenberg, SH; Shi, Y; Thomas, S; Wernet, W; Zhu, GD1
Colon-Lopez, M; Donawho, C; Ellis, PA; Frost, DJ; Giranda, VL; Kinders, R; LeBlond, D; Lin, CT; Liu, X; Luo, Y; Palma, J; Rodriguez, LE; Saltarelli, M; Shi, Y1
Burd, R; Limesand, KH; Sittadjody, S; Thangasamy, T1
Griss, J; Joukhadar, C; Karimian-Teherani, D; Poeppl, W; Rous, W; Skorjanec, S; Soleiman, A; Thallinger, C; Tzaneva, S; Weinlich, G1
Bontcheva-Diaz, V; Bouska, JJ; Donawho, CK; Frost, DJ; Gandhi, VB; Giranda, VL; Gong, J; Johnson, EF; Klinghofer, V; Liu, X; Luo, Y; Marsh, KC; Olson, AM; Osterling, DJ; Penning, TD; Shi, Y; Zhu, GD1
Bouska, JJ; Donawho, CK; Ellis, PA; Frost, DJ; Giranda, VL; Johnson, EF; Leverson, J; Liu, X; Luo, Y; Marcotte, PA; Olson, AM; Osterling, DJ; Penning, TD; Przytulinska, M; Rodriguez, LE; Shi, Y; Soni, N; Stavropoulos, J; Thomas, S; Tong, Y1
Adanja, I; Amighi, K; Debeir, O; Decaestecker, C; Deleuze, P; Hecq, J; Kiss, R; Mathieu, V; Roland, I; Saussez, S; Wauthoz, N1
Aldrich, W; Triozzi, PL1
Bontcheva-Diaz, V; Bouska, JJ; Buchanan, FG; Bukofzer, GT; Donawho, CK; Frost, DJ; Fry, EH; Gandhi, VB; Giranda, VL; Gong, J; Johnson, EF; Klinghofer, V; Liu, X; Luo, Y; Marsh, KC; Olson, AM; Osterling, DJ; Park, CH; Penning, TD; Rodriguez, LE; Shi, Y; Thomas, S; Zhu, GD1
Camaioni, E; Dantzer, F; Dorio, AS; Gold, B; Graziani, G; Leonetti, C; Muzi, A; Pellicciari, R; Scarsella, M; Shah, GM; Tentori, L; Xu, W; Zhang, J1
Andrade, LN; Chammas, R; de Oliveira, SI; Fernandes, PD; Jancar, S; Nonogaki, S; Onuchic, AC; Pinheiro, MC; Rohde, CB1
Alitalo, K; Kim, I; Kim, KE; Kim, M; Koh, BI; Koh, GY; Koh, YJ; Nam, DH1
Di, Y; Gong, J; Guo, JL; He, L; Jin, JL; Lu, YJ; Noteborn, MH; Qu, S; Sun, J; Xia, JJ; Xie, YY; Yin, TJ1
Caccuri, AM; Cuzzocrea, S; Dorio, AS; Federici, G; Graziani, G; Mazzon, E; Muzi, A; Sau, A; Tentori, L; Vernole, P1
Chen, J; Huang, Y; Li, Z; Liu, P; Ren, J; Wu, G; Zhang, C; Zhang, R; Zhu, F1
Chang, Z; Chen, D; Guo, J; Jia, D; Jin, C; Liu, J; Rao, W; Wang, C; Wang, S; Zhang, M1
Kaneda, Y; Katayama, I; Kiyohara, E; Tamai, K1
Mateus, C; Robert, C1
Chakraborty, G; Kumar, S; Kundu, GC; Mishra, R; Patil, TV1
Apetoh, L; Bruchard, M; Chalmin, F; Ghiringhelli, F; Hervieu, A; Mignot, G; Rébé, C; Vabres, P; Végran, F1
Becker, JC; Paschen, A; Ugurel, S1
Becker, JC; Bröcker, EB; Fischer, WH; Kirst, A; Lutz, WK; Wack, C1
Halaschek-Wiener, J; Jansen, B; Kloog, Y; Wacheck, V1
Bökönyi, G; Horváth, A; Kéri, G; Szende, B1
D'Amati, G; Graziani, G; Kalish, V; Leonetti, C; Portarena, I; Scarsella, M; Tentori, L; Vergati, M; Xu, W; Zhang, J; Zupi, G1
Fei, J; Guo, LH; Lin, GW; Sun, DJ; Wang, JS1
Alemu, C; Calvin, D; Graziani, G; Hoover, R; Lapidus, R; Leonetti, C; Morgan, L; Scarsella, M; Tang, Z; Tentori, L; Vergati, M; Woznizk, K; Xu, W; Zhang, J1
Camoutsis, C; Papageorgiou, A; Trafalis, DT1
Forini, O; Gold, B; Graziani, G; Lacal, PM; Leonetti, C; Li, W; Muzi, A; Ruffini, F; Scarsella, M; Tentori, L; Vergati, M; Zhang, J1
Abdel-Wahab, OI; Abdel-Wahab, Z; Chu, E; Dewhirst, MW; Friedman, HS; Ko, SH; Pruitt, SK; Tyler, DS; Ueno, T; Yoo, JS; Yoshimoto, Y1
Bauder-Wüst, U; Eisenhut, M; Eskerski, H; Haberkorn, U; Wolf, M1
Furuhashi, M; Kawamura, T; Ogawa, Y; Shimada, S; Tsukamoto, K1
Fujita, K; Hasegawa, K; Inoue, S; Ishihara, K; Ito, S; Wakamatsu, K1
Newlands, ES; Porteous, JK; Wedge, SR1
Goodger, S; Kelly, J; Margison, GP; Middleton, MR; Thatcher, N1
Gadjeva, V; Raikova, E; Zheleva, A1
Bocsi, J; Hidvégi, M; Lapis, K; Paku, S; Prónai, L; Rásó, E; Szende, B; Tömösközi-Farkas, R1
Becker, JC; Bröcker, EB; Fischer, WH; Lutz, WK; Wack, C1
Chen, SH; Liang, YC; Lin, CL; Liu, JD; Tsai, SH1
Charak, BS; Mazumder, A; Sadowski, RM1
Gamel, JW; Niederkorn, JY; Sanborn, GE1
Furukawa, M; Hamada, T; Ishii, M; Kono, T; Taniguchi, S; Tanii, T1
Aukerman, SL; Biernat, L; Corbett, TH; LoRusso, PM; Polin, L; Redman, BG; Valdivieso, M1
Baig, G; Chubb, D; Gibson, NW; Goddard, C; Hickman, JA; Langdon, SP; Slack, JA; Stevens, MF; Stone, R; Vickers, L1

Reviews

1 review(s) available for dacarbazine and B16 Melanoma

ArticleYear
[Anti-CTLA-4 monoclonal antibody: a major step in the treatment of metastatic melanoma].
    Medecine sciences : M/S, 2011, Volume: 27, Issue:10

    Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antigens, Neoplasm; Antineoplastic Agents, Alkylating; Autoimmune Diseases; Cancer Vaccines; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Combined Modality Therapy; CTLA-4 Antigen; Dacarbazine; Digestive System Diseases; Drug Screening Assays, Antitumor; Humans; Immunotherapy; Immunotherapy, Active; Ipilimumab; Melanoma; Melanoma, Experimental; Mice; Monitoring, Immunologic; Nervous System Diseases; Vaccines, Subunit

2011

Other Studies

66 other study(ies) available for dacarbazine and B16 Melanoma

ArticleYear
Glutathione S-Transferase π-Activatable O
    Journal of medicinal chemistry, 2018, 03-08, Volume: 61, Issue:5

    Topics: Animals; Antineoplastic Agents; Azo Compounds; Cell Proliferation; Drug Design; Epithelial Cells; Glutathione S-Transferase pi; Heterografts; Humans; Melanoma, Experimental; Mice; Nitric Oxide; Nitric Oxide Donors

2018
Metformin pretreatment reduces effect to dacarbazine and suppresses melanoma cell resistance.
    Cell biology international, 2022, Volume: 46, Issue:1

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Antineoplastic Agents, Alkylating; Antioxidants; Cell Line, Tumor; Dacarbazine; Drug Resistance, Neoplasm; Malondialdehyde; Melanoma, Experimental; Metformin; Mice; NF-E2-Related Factor 2; NF-kappa B; Oxidative Stress; Skin Neoplasms; Tumor Suppressor Protein p53

2022
Dacarbazine alone or associated with melanoma-bearing cancer pain model induces painful hypersensitivity by TRPA1 activation in mice.
    International journal of cancer, 2020, 05-15, Volume: 146, Issue:10

    Topics: Animals; Antineoplastic Agents, Alkylating; Dacarbazine; HEK293 Cells; Humans; Hyperalgesia; Melanoma, Experimental; Mice; Mice, Inbred C57BL; TRPA1 Cation Channel

2020
Cancer Cell Membrane Camouflaged Mesoporous Silica Nanoparticles Combined with Immune Checkpoint Blockade for Regulating Tumor Microenvironment and Enhancing Antitumor Therapy.
    International journal of nanomedicine, 2021, Volume: 16

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Death; Cell Membrane; Cell Proliferation; Cell Survival; Combined Modality Therapy; Dacarbazine; Humans; Immune Checkpoint Inhibitors; Melanoma, Experimental; Mice, Inbred C57BL; Nanoparticles; Particle Size; Porosity; Silicon Dioxide; Static Electricity; Tumor Microenvironment

2021
In Vitro Effects of Selective COX and LOX Inhibitors and Their Combinations with Antineoplastic Drugs in the Mouse Melanoma Cell Line B16F10.
    International journal of molecular sciences, 2021, Jun-17, Volume: 22, Issue:12

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cells, Cultured; Cyclooxygenase Inhibitors; Dacarbazine; Dose-Response Relationship, Drug; Drug Synergism; Lipoxygenase Inhibitors; Melanoma, Experimental; Mice; Molecular Structure; Temozolomide

2021
Codonopsis pilosula polysaccharide in synergy with dacarbazine inhibits mouse melanoma by repolarizing M2-like tumor-associated macrophages into M1-like tumor-associated macrophages.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021, Volume: 142

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Proliferation; Codonopsis; Cytokines; Dacarbazine; Female; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Polysaccharides; Reishi; Tumor Burden; Tumor-Associated Macrophages

2021
TCTP as a therapeutic target in melanoma treatment.
    British journal of cancer, 2017, Aug-22, Volume: 117, Issue:5

    Topics: Animals; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Dacarbazine; Female; Gene Expression; Gene Silencing; Humans; Melanoma; Melanoma, Experimental; Mice; Mice, Inbred C57BL; RNA, Messenger; RNA, Small Interfering; Sertraline; Skin Neoplasms; Transfection; Tumor Protein, Translationally-Controlled 1; Tumor Stem Cell Assay; Tumor Suppressor Protein p53

2017
Cytotoxic antimelanoma drugs suppress the activation of M2 macrophages.
    Experimental dermatology, 2018, Volume: 27, Issue:1

    Topics: Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antineoplastic Agents; B7-H1 Antigen; Dacarbazine; Female; Japan; Lectins, C-Type; Leukocytes, Mononuclear; Macrophages; Mannose Receptor; Mannose-Binding Lectins; Melanoma; Melanoma, Cutaneous Malignant; Melanoma, Experimental; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Monocytes; Nimustine; Receptors, Cell Surface; RNA, Messenger; Skin Neoplasms; Vincristine

2018
Dacarbazine nanoparticle topical delivery system for the treatment of melanoma.
    Scientific reports, 2017, 11-28, Volume: 7, Issue:1

    Topics: Administration, Topical; Animals; Antineoplastic Agents, Alkylating; Cell Line, Tumor; Cell Survival; Dacarbazine; Drug Carriers; Drug Delivery Systems; Drug Liberation; Hydrogen-Ion Concentration; Melanoma; Melanoma, Experimental; Mice; Nanoparticles; Particle Size; Permeability; Viscosity

2017
Inflammatory Cytokine Pattern Is Sex-Dependent in Mouse Cutaneous Melanoma Experimental Model.
    Journal of immunology research, 2017, Volume: 2017

    Topics: Animals; Antineoplastic Agents, Alkylating; Carcinogenesis; Cytokines; Dacarbazine; Disease Models, Animal; Disease Progression; Female; Humans; Inflammation Mediators; Male; Melanoma; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Sex; Skin Neoplasms

2017
Solid Lipid Nanoparticles Carrying Temozolomide for Melanoma Treatment. Preliminary In Vitro and In Vivo Studies.
    International journal of molecular sciences, 2018, Jan-24, Volume: 19, Issue:2

    Topics: Animals; Biomarkers; Cell Line, Tumor; Dacarbazine; Disease Models, Animal; Drug Stability; Female; Humans; Immunohistochemistry; Melanoma; Melanoma, Experimental; Mice; Molecular Structure; Nanoparticles; Neoplastic Stem Cells; Temozolomide

2018
Senescence-associated secretory factors induced by cisplatin in melanoma cells promote non-senescent melanoma cell growth through activation of the ERK1/2-RSK1 pathway.
    Cell death & disease, 2018, 02-15, Volume: 9, Issue:3

    Topics: A549 Cells; Animals; Antineoplastic Agents; Cell Proliferation; Cellular Senescence; Cisplatin; Cyclin-Dependent Kinase Inhibitor p21; Dacarbazine; Drug Resistance, Neoplasm; HeLa Cells; Humans; Interleukin-1alpha; Melanoma; Melanoma, Experimental; Mice; Mice, Inbred BALB C; Mice, Nude; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Ribosomal Protein S6 Kinases, 90-kDa; Secretory Pathway; Signal Transduction; Skin Neoplasms; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays

2018
Reversing effect of Lupeol on vasculogenic mimicry in murine melanoma progression.
    Microvascular research, 2019, Volume: 121

    Topics: AC133 Antigen; Angiogenesis Inhibitors; Animals; Antigens, CD; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Biological Mimicry; Cadherins; Dacarbazine; Disease Progression; Drug Resistance, Neoplasm; Endothelial Progenitor Cells; Male; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Neoplastic Stem Cells; Neovascularization, Pathologic; Pentacyclic Triterpenes; Phenotype; Platelet Endothelial Cell Adhesion Molecule-1; Tumor Burden

2019
A peptide-modified solid lipid nanoparticle formulation of paclitaxel modulates immunity and outperforms dacarbazine in a murine melanoma model.
    Biomaterials science, 2019, Feb-26, Volume: 7, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Calreticulin; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Cytokines; Dacarbazine; Disease Models, Animal; Female; Lung Neoplasms; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Microscopy, Fluorescence; Nanoparticles; Paclitaxel; Peptides; Survival Rate; Tissue Distribution

2019
Combination therapy with dacarbazine and statins improved the survival rate in mice with metastatic melanoma.
    Journal of cellular physiology, 2019, Volume: 234, Issue:10

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Dacarbazine; Female; Fluvastatin; Gene Expression Regulation; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lung Neoplasms; Melanoma, Experimental; Mice, Inbred C57BL; Signal Transduction; Simvastatin; Skin Neoplasms; Tumor Burden

2019
Efficacy of oregonin investigated by non-invasive evaluation in a B16 mouse melanoma model.
    Experimental dermatology, 2013, Volume: 22, Issue:12

    Topics: Animals; Antineoplastic Agents; Antioxidants; Dacarbazine; Diarylheptanoids; Fluorodeoxyglucose F18; Melanoma, Experimental; Mice; Mice, Inbred BALB C; Mice, Nude; Multimodal Imaging; Neoplasm Transplantation; Neoplasms, Experimental; Plant Extracts; Positron-Emission Tomography; Tomography, X-Ray Computed

2013
Blockade of A2b adenosine receptor reduces tumor growth and immune suppression mediated by myeloid-derived suppressor cells in a mouse model of melanoma.
    Neoplasia (New York, N.Y.), 2013, Volume: 15, Issue:12

    Topics: Adenosine A2 Receptor Antagonists; Aminopyridines; Animals; Antineoplastic Agents; Cell Line, Tumor; Chemokine CCL2; Dacarbazine; Drug Screening Assays, Antitumor; Drug Synergism; Female; Immunosuppressive Agents; Interleukin-10; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Myeloid Cells; Natural Killer T-Cells; Neoplasm Transplantation; Receptor, Adenosine A2B; Tumor Burden; Tumor Escape; Tumor Microenvironment; Xanthines

2013
Preclinical evaluation of IL2-based immunocytokines supports their use in combination with dacarbazine, paclitaxel and TNF-based immunotherapy.
    Cancer immunology, immunotherapy : CII, 2014, Volume: 63, Issue:9

    Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Combined Modality Therapy; Dacarbazine; Drug Synergism; Female; Immunotherapy; Interleukin-2; Melanoma, Experimental; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Paclitaxel; Recombinant Fusion Proteins; Tissue Distribution; Tumor Necrosis Factor-alpha

2014
A human monoclonal antibody targeting the stem cell factor receptor (c-Kit) blocks tumor cell signaling and inhibits tumor growth.
    Cancer biology & therapy, 2014, Volume: 15, Issue:9

    Topics: Animals; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cell Proliferation; Cisplatin; Dacarbazine; Etoposide; Female; Heterografts; Humans; Immunoglobulin G; Lung Neoplasms; Melanoma, Experimental; Mice, Nude; Mitogen-Activated Protein Kinase Kinases; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-kit; Signal Transduction; Small Cell Lung Carcinoma

2014
Modulation of radiochemoimmunotherapy-induced B16 melanoma cell death by the pan-caspase inhibitor zVAD-fmk induces anti-tumor immunity in a HMGB1-, nucleotide- and T-cell-dependent manner.
    Cell death & disease, 2015, May-14, Volume: 6

    Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Apyrase; B7-2 Antigen; Caspase Inhibitors; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Chemoradiotherapy; Combined Modality Therapy; Dacarbazine; Dendritic Cells; Histocompatibility Antigens Class II; HMGB1 Protein; Homeodomain Proteins; Hyperthermia, Induced; Interferon-gamma; Lymphocyte Activation; Macrophages, Peritoneal; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mice, Knockout; Myeloid Differentiation Factor 88; Radiation, Ionizing; Tumor Necrosis Factor-alpha

2015
Antitumor effect of pharmacologic ascorbate in the B16 murine melanoma model.
    Free radical biology & medicine, 2015, Volume: 87

    Topics: Animals; Antineoplastic Agents; Ascorbic Acid; Dacarbazine; DNA Damage; Histones; Humans; Melanoma, Experimental; Mice; Phosphorylation

2015
CCR4 is critically involved in effective antitumor immunity in mice bearing intradermal B16 melanoma.
    Cancer letters, 2016, 08-01, Volume: 378, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Cell Line, Tumor; Cell Proliferation; Chemokine CCL22; Dacarbazine; Dendritic Cells; Genotype; Lymph Nodes; Lymphocytes, Tumor-Infiltrating; Melanoma, Experimental; Mice, Inbred C57BL; Mice, Knockout; Phenotype; Receptors, CCR4; Signal Transduction; Th17 Cells; Time Factors; Transfection; Tumor Burden

2016
NRF2 and glutathione are key resistance mediators to temozolomide in glioma and melanoma cells.
    Oncotarget, 2016, Jul-26, Volume: 7, Issue:30

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Buthionine Sulfoximine; Cell Line, Tumor; Dacarbazine; Drug Resistance, Neoplasm; Female; Glioma; Glutathione; Humans; Melanoma; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mice, Nude; NF-E2-Related Factor 2; Temozolomide; Xenograft Model Antitumor Assays

2016
Discovery and SAR of 2-(1-propylpiperidin-4-yl)-1H-benzimidazole-4-carboxamide: A potent inhibitor of poly(ADP-ribose) polymerase (PARP) for the treatment of cancer.
    Bioorganic & medicinal chemistry, 2008, Jul-15, Volume: 16, Issue:14

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Breast Neoplasms; Cisplatin; Dacarbazine; Enzyme Inhibitors; Humans; Melanoma, Experimental; Mice; Poly(ADP-ribose) Polymerase Inhibitors; Structure-Activity Relationship; Temozolomide; Transplantation, Heterologous; Xenograft Model Antitumor Assays

2008
An enzyme-linked immunosorbent poly(ADP-ribose) polymerase biomarker assay for clinical trials of PARP inhibitors.
    Analytical biochemistry, 2008, Oct-15, Volume: 381, Issue:2

    Topics: Animals; Antineoplastic Agents; Benzimidazoles; Biomarkers; Clinical Trials as Topic; Dacarbazine; Disease Models, Animal; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Female; Humans; Melanoma, Experimental; Mice; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Temozolomide

2008
Tyrosinase overexpression promotes ATM-dependent p53 phosphorylation by quercetin and sensitizes melanoma cells to dacarbazine.
    Cellular oncology : the official journal of the International Society for Cellular Oncology, 2008, Volume: 30, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Apoptosis; Ataxia Telangiectasia Mutated Proteins; Blotting, Western; Cell Cycle Proteins; Cell Line, Tumor; Dacarbazine; DNA-Binding Proteins; Humans; Melanoma, Experimental; Monophenol Monooxygenase; Phosphorylation; Protein Serine-Threonine Kinases; Quercetin; Reactive Oxygen Species; Transfection; Tumor Suppressor Protein p53; Tumor Suppressor Proteins

2008
Orally administered rapamycin, dacarbazine or both for treatment of human melanoma evaluated in severe combined immunodeficiency mice.
    Pharmacology, 2008, Volume: 82, Issue:3

    Topics: Administration, Oral; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Dacarbazine; Dose-Response Relationship, Drug; Female; Humans; Melanoma, Experimental; Mice; Mice, SCID; Random Allocation; Sirolimus; Xenograft Model Antitumor Assays

2008
Discovery of the Poly(ADP-ribose) polymerase (PARP) inhibitor 2-[(R)-2-methylpyrrolidin-2-yl]-1H-benzimidazole-4-carboxamide (ABT-888) for the treatment of cancer.
    Journal of medicinal chemistry, 2009, Jan-22, Volume: 52, Issue:2

    Topics: Animals; Antineoplastic Agents; Area Under Curve; Benzimidazoles; Biological Availability; Carboplatin; Cyclophosphamide; Dacarbazine; Dogs; Enzyme Inhibitors; Female; Haplorhini; Humans; Magnetic Resonance Spectroscopy; Melanoma, Experimental; Mice; Mice, SCID; Poly(ADP-ribose) Polymerase Inhibitors; Rats; Temozolomide

2009
Synthesis and evaluation of a new generation of orally efficacious benzimidazole-based poly(ADP-ribose) polymerase-1 (PARP-1) inhibitors as anticancer agents.
    Journal of medicinal chemistry, 2009, Nov-12, Volume: 52, Issue:21

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Benzimidazoles; Biological Availability; Cell Line, Tumor; Dacarbazine; Drug Synergism; Female; Humans; Male; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Oxadiazoles; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Pyridines; Structure-Activity Relationship; Temozolomide; Transplantation, Heterologous

2009
In vivo assessment of temozolomide local delivery for lung cancer inhalation therapy.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2010, Mar-18, Volume: 39, Issue:5

    Topics: Administration, Inhalation; Animals; Antineoplastic Agents; Cell Line, Tumor; Chromatography, High Pressure Liquid; Dacarbazine; Female; Fluorescent Dyes; Lung Neoplasms; Melanoma, Experimental; Mice; Particle Size; Reproducibility of Results; Temozolomide

2010
Effects of interleukin-1 receptor antagonist and chemotherapy on host-tumor interactions in established melanoma.
    Anticancer research, 2010, Volume: 30, Issue:2

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Antirheumatic Agents; Blotting, Western; Cell Proliferation; Dacarbazine; Docetaxel; Drug Therapy, Combination; Extracellular Fluid; Female; Flow Cytometry; Immunoenzyme Techniques; Interleukin 1 Receptor Antagonist Protein; Macrophages; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; T-Lymphocytes, Regulatory; Taxoids; Temozolomide; Tumor Cells, Cultured

2010
Optimization of phenyl-substituted benzimidazole carboxamide poly(ADP-ribose) polymerase inhibitors: identification of (S)-2-(2-fluoro-4-(pyrrolidin-2-yl)phenyl)-1H-benzimidazole-4-carboxamide (A-966492), a highly potent and efficacious inhibitor.
    Journal of medicinal chemistry, 2010, Apr-22, Volume: 53, Issue:8

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Biological Availability; Blood-Brain Barrier; BRCA1 Protein; Carboplatin; Cell Line, Tumor; Crystallography, X-Ray; Dacarbazine; Drug Screening Assays, Antitumor; Female; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mice, SCID; Models, Molecular; Neoplasm Transplantation; Poly(ADP-ribose) Polymerase Inhibitors; Stereoisomerism; Structure-Activity Relationship; Temozolomide; Transplantation, Heterologous

2010
Pharmacological inhibition of poly(ADP-ribose) polymerase (PARP) activity in PARP-1 silenced tumour cells increases chemosensitivity to temozolomide and to a N3-adenine selective methylating agent.
    Current cancer drug targets, 2010, Volume: 10, Issue:4

    Topics: Animals; Antineoplastic Agents; Blotting, Western; Cell Division; Cell Line, Tumor; Dacarbazine; Drug Synergism; Enzyme Inhibitors; Flow Cytometry; G2 Phase; HeLa Cells; Humans; Melanoma, Experimental; Methylation; Mice; Netropsin; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Temozolomide

2010
Platelet-activating factor receptor (PAF-R)-dependent pathways control tumour growth and tumour response to chemotherapy.
    BMC cancer, 2010, May-13, Volume: 10

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Azepines; Carcinoma, Ehrlich Tumor; Caspase 3; Cell Proliferation; Cyclooxygenase 2; Dacarbazine; Dinoprostone; Enzyme-Linked Immunosorbent Assay; Female; Flow Cytometry; Galectin 3; Immunohistochemistry; Macrophages; Male; Melanoma, Experimental; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Neovascularization, Pathologic; Nitric Oxide; Phenotype; Platelet Membrane Glycoproteins; Receptors, G-Protein-Coupled; Signal Transduction; Time Factors; Triazoles; Tumor Burden; Vascular Endothelial Growth Factor A

2010
CXCR4 signaling regulates metastasis of chemoresistant melanoma cells by a lymphatic metastatic niche.
    Cancer research, 2010, Dec-15, Volume: 70, Issue:24

    Topics: AC133 Antigen; Animals; Antigens, CD; Benzylamines; Cell Movement; Chemokine CXCL12; Cyclams; Dacarbazine; Drug Resistance, Neoplasm; Endothelial Cells; Glycoproteins; Heterocyclic Compounds; Lung Neoplasms; Lymphatic Metastasis; Lymphatic Vessels; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mice, Transgenic; Peptides; Receptors, CXCR4; Signal Transduction

2010
PTD4-apoptin protein and dacarbazine show a synergistic antitumor effect on B16-F1 melanoma in vitro and in vivo.
    European journal of pharmacology, 2011, Mar-01, Volume: 654, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Capsid Proteins; Cell Line; Cell Line, Tumor; Dacarbazine; Drug Synergism; Female; Humans; Melanoma; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Recombinant Fusion Proteins

2011
The glutathione transferase inhibitor 6-(7-nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol (NBDHEX) increases temozolomide efficacy against malignant melanoma.
    European journal of cancer (Oxford, England : 1990), 2011, Volume: 47, Issue:8

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cell Proliferation; Dacarbazine; DNA Methylation; Drug Synergism; Glutathione Transferase; Humans; Inhibitory Concentration 50; Male; Melanoma; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Oxadiazoles; Temozolomide

2011
Combinational therapy of interferon-α and chemotherapy normalizes tumor vasculature by regulating pericytes including the novel marker RGS5 in melanoma.
    Journal of immunotherapy (Hagerstown, Md. : 1997), 2011, Volume: 34, Issue:3

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Biomarkers; Blood Vessels; Combined Modality Therapy; Dacarbazine; Down-Regulation; Female; Gene Expression; Interferon-alpha; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Neovascularization, Pathologic; Pericytes; RGS Proteins

2011
Inhibition of B16 murine melanoma metastasis and enhancement of immunity by fever-range whole body hyperthermia.
    International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group, 2011, Volume: 27, Issue:3

    Topics: Animals; Antineoplastic Agents; Cisplatin; Dacarbazine; Female; Fever; Hyperthermia, Induced; Immunity; Lung Neoplasms; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Neoplasm Metastasis

2011
The combination of chemotherapy with HVJ-E containing Rad51 siRNA elicited diverse anti-tumor effects and synergistically suppressed melanoma.
    Gene therapy, 2012, Volume: 19, Issue:7

    Topics: Animals; Antigens, Nuclear; Antineoplastic Agents, Alkylating; Dacarbazine; DNA Breaks, Double-Stranded; DNA Repair; DNA-Binding Proteins; Female; Ku Autoantigen; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Rad51 Recombinase; RNA, Small Interfering; Sendai virus; Skin Neoplasms

2012
Semaphorin 3A suppresses tumor growth and metastasis in mice melanoma model.
    PloS one, 2012, Volume: 7, Issue:3

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Western; Case-Control Studies; Cell Adhesion; Cell Movement; Cell Proliferation; Cells, Cultured; Curcumin; Dacarbazine; Human Umbilical Vein Endothelial Cells; Humans; Immunoenzyme Techniques; Liver Neoplasms; Lung Neoplasms; Male; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Neovascularization, Pathologic; Phosphorylation; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Semaphorin-3A; Wound Healing

2012
Dacarbazine-mediated upregulation of NKG2D ligands on tumor cells activates NK and CD8 T cells and restrains melanoma growth.
    The Journal of investigative dermatology, 2013, Volume: 133, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Dacarbazine; Disease Models, Animal; Humans; Interferon-gamma; Killer Cells, Natural; Ligands; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mice, Nude; NK Cell Lectin-Like Receptor Subfamily K; Skin Neoplasms; Up-Regulation

2013
Dacarbazine in melanoma: from a chemotherapeutic drug to an immunomodulating agent.
    The Journal of investigative dermatology, 2013, Volume: 133, Issue:2

    Topics: Animals; CD8-Positive T-Lymphocytes; Dacarbazine; Humans; Killer Cells, Natural; Melanoma, Experimental; NK Cell Lectin-Like Receptor Subfamily K; Skin Neoplasms

2013
Chemoimmunotherapy for melanoma with dacarbazine and 2,4-dinitrochlorobenzene elicits a specific T cell-dependent immune response.
    Cancer immunology, immunotherapy : CII, 2002, Volume: 51, Issue:8

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Combined Modality Therapy; Dacarbazine; Dinitrochlorobenzene; Immunotherapy; Irritants; Lung Neoplasms; Lymphocytes, Tumor-Infiltrating; Melanoma; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Neoplasm Metastasis; Neoplasm Transplantation; Ribonucleases; RNA, Messenger; T-Lymphocytes; Time Factors; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

2002
Farnesyl thiosalicylic acid chemosensitizes human melanoma in vivo.
    The Journal of investigative dermatology, 2003, Volume: 120, Issue:1

    Topics: Animals; Antineoplastic Agents; Dacarbazine; Enzyme Inhibitors; Farnesol; Female; Humans; Melanoma, Experimental; Mice; Mice, SCID; Neoplasm Transplantation; ras Proteins; Salicylates; Transplantation, Heterologous; Tumor Cells, Cultured

2003
Effect of a novel somatostatin analogue combined with cytotoxic drugs on human tumour xenografts and metastasis of B16 melanoma.
    British journal of cancer, 2003, Jan-13, Volume: 88, Issue:1

    Topics: Animals; Antineoplastic Agents; Dacarbazine; Disease Models, Animal; Drug Therapy, Combination; Etoposide; Humans; Lymphoma; Male; Melanoma, Experimental; Mice; Mice, Inbred CBA; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms, Experimental; Peptides, Cyclic; Somatostatin; Xenograft Model Antitumor Assays

2003
Systemic administration of GPI 15427, a novel poly(ADP-ribose) polymerase-1 inhibitor, increases the antitumor activity of temozolomide against intracranial melanoma, glioma, lymphoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2003, Nov-01, Volume: 9, Issue:14

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Drug Synergism; Enzyme Inhibitors; Glioblastoma; Humans; Lymphoma; Male; Melanoma, Experimental; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Survival Rate; Temozolomide; Transplantation, Heterologous; Tumor Cells, Cultured

2003
[Construction of an angiostatin eukaryotic expression vector and characterization of its inhibitory efficiency in B16 melanoma bearing mice].
    Shi yan sheng wu xue bao, 2002, Volume: 35, Issue:4

    Topics: Angiostatins; Animals; Antineoplastic Agents, Alkylating; Cell Line, Tumor; Dacarbazine; Genetic Therapy; Genetic Vectors; Melanoma, Experimental; Mice; Mice, Inbred C57BL

2002
Brain distribution and efficacy as chemosensitizer of an oral formulation of PARP-1 inhibitor GPI 15427 in experimental models of CNS tumors.
    International journal of oncology, 2005, Volume: 26, Issue:2

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Area Under Curve; Biological Availability; Blood-Brain Barrier; Brain; Cell Line, Tumor; Central Nervous System Neoplasms; Chromatography, Liquid; Dacarbazine; Disease Models, Animal; Enzyme Inhibitors; Flow Cytometry; G2 Phase; Humans; Inhibitory Concentration 50; Kinetics; Mass Spectrometry; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Organic Chemicals; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley; Temozolomide; Time Factors

2005
Research on the anti-tumour effect of steroid lactam alkylator (NSC-294859) in comparison with conventional chemotherapeutics in malignant melanoma.
    Melanoma research, 2005, Volume: 15, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Azasteroids; Cell Line, Tumor; Cisplatin; Dacarbazine; Drug Screening Assays, Antitumor; Esters; Female; Humans; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasm Transplantation; Nitrogen Mustard Compounds

2005
Poly(ADP-ribose) glycohydrolase inhibitor as chemosensitiser of malignant melanoma for temozolomide.
    European journal of cancer (Oxford, England : 1990), 2005, Volume: 41, Issue:18

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Dacarbazine; Drug Interactions; Fluorenes; Glycoside Hydrolases; Melanoma; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Skin Neoplasms; Temozolomide

2005
Optimizing a novel regional chemotherapeutic agent against melanoma: hyperthermia-induced enhancement of temozolomide cytotoxicity.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2006, Jan-01, Volume: 12, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Cell Line, Tumor; Chemotherapy, Cancer, Regional Perfusion; Combined Modality Therapy; Cytotoxicity, Immunologic; Dacarbazine; Humans; Hyperthermia, Induced; Immunohistochemistry; Ki-67 Antigen; Melanoma, Experimental; Rats; Temozolomide; Xenograft Model Antitumor Assays

2006
Alkylating benzamides with melanoma cytotoxicity: experimental chemotherapy in a mouse melanoma model.
    Melanoma research, 2006, Volume: 16, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Benzamides; Chlorambucil; Dacarbazine; Disease Models, Animal; Humans; Injections, Intraperitoneal; Male; Maximum Tolerated Dose; Melanoma, Experimental; Mice; Mice, Inbred BALB C; Mice, Nude; Skin Neoplasms; Survival Rate; Tumor Cells, Cultured

2006
Improving chemotherapeutic drug penetration in melanoma by imatinib mesylate.
    Journal of dermatological science, 2008, Volume: 51, Issue:3

    Topics: Animals; Antineoplastic Agents; Benzamides; Biological Transport, Active; Dacarbazine; Female; Imatinib Mesylate; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Receptor, Platelet-Derived Growth Factor beta

2008
Changes in plasma 5-S-cysteinyldopa concentration in B16 melanoma-bearing mice treated with interferon-beta or dacarbazine.
    Melanoma research, 1993, Volume: 3, Issue:5

    Topics: Animals; Biomarkers, Tumor; Dacarbazine; Dopamine; Interferon-beta; Melanoma, Experimental; Mice; Mice, Inbred C57BL

1993
Effect of single and multiple administration of an O6-benzylguanine/temozolomide combination: an evaluation in a human melanoma xenograft model.
    Cancer chemotherapy and pharmacology, 1997, Volume: 40, Issue:3

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Dacarbazine; Drug Administration Schedule; Guanine; Humans; Melanoma, Experimental; Methyltransferases; Mice; Mice, Nude; Neoplasm Transplantation; O(6)-Methylguanine-DNA Methyltransferase; Temozolomide; Tumor Cells, Cultured

1997
Four-hourly scheduling of temozolomide improves tumour growth delay but not therapeutic index in A375M melanoma xenografts.
    Cancer chemotherapy and pharmacology, 2000, Volume: 45, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Dacarbazine; Drug Administration Schedule; Guanine; Humans; Male; Melanoma, Experimental; Mice; Mice, Nude; Neoplasm Transplantation; O(6)-Methylguanine-DNA Methyltransferase; Temozolomide; Transplantation, Heterologous

2000
Modulating effect of new potential antimelanomic agents, spin-labeled triazenes and nitrosoureas on the DOPA-oxidase activity of tyrosinase.
    Cancer biochemistry biophysics, 1999, Volume: 17, Issue:1-2

    Topics: Animals; Antineoplastic Agents, Alkylating; Catalysis; Cyclic N-Oxides; Dacarbazine; Dihydroxyphenylalanine; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Lomustine; Melanoma, Experimental; Mice; Molecular Structure; Monophenol Monooxygenase; Neoplasm Proteins; Nitrosourea Compounds; Oxidation-Reduction; Piperidines; Plant Proteins; Spectrophotometry; Spin Labels; Structure-Activity Relationship; Triazenes; Tumor Cells, Cultured

1999
MSC, a new benzoquinone-containing natural product with antimetastatic effect.
    Cancer biotherapy & radiopharmaceuticals, 1999, Volume: 14, Issue:4

    Topics: Animals; Benzoquinones; Colonic Neoplasms; Colorectal Neoplasms; Dacarbazine; Humans; Lectins; Liver Neoplasms; Lung Neoplasms; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Neoplasm Metastasis; Plant Extracts; Transplantation, Heterologous

1999
Chemoimmunotherapy for melanoma with dacarbazine and 2,4-dinitrochlorobenzene: results from a murine tumour model.
    Melanoma research, 2001, Volume: 11, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Combined Modality Therapy; Dacarbazine; Dinitrochlorobenzene; Dose-Response Relationship, Drug; Female; Immunotherapy; Irritants; Lung Neoplasms; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Neoplasm Metastasis; Neoplasms, Experimental; Time Factors

2001
Inhibition of melanoma growth and metastasis by combination with (-)-epigallocatechin-3-gallate and dacarbazine in mice.
    Journal of cellular biochemistry, 2001, Volume: 83, Issue:4

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Catechin; Cell Aggregation; Cell Communication; Cell Movement; Cell Transformation, Neoplastic; Dacarbazine; Drug Screening Assays, Antitumor; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Growth Inhibitors; Injections, Intraperitoneal; Lung Neoplasms; Male; Matrix Metalloproteinases; Melanoma, Experimental; Mice; Neoplasm Transplantation; Phosphorylation; Protein-Tyrosine Kinases; Survival Rate; Tea; Tumor Cells, Cultured; Tumor Stem Cell Assay; Tyrosine

2001
Antitumor effect of interferon plus cyclosporine A following chemotherapy for disseminated melanoma.
    Cancer research, 1992, Dec-01, Volume: 52, Issue:23

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Chromium; Cisplatin; Cyclosporine; Dacarbazine; Drug Synergism; Female; Immunotherapy, Adoptive; Interferons; Major Histocompatibility Complex; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Spleen; T-Lymphocytes, Regulatory

1992
Efficacy of dacarbazine (DTIC) in preventing metastases arising from intraocular melanomas in mice.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 1992, Volume: 230, Issue:2

    Topics: Animals; Anterior Eye Segment; Dacarbazine; Eye Enucleation; Eye Neoplasms; Female; Lung Neoplasms; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Survival Rate; Time Factors; Verapamil

1992
Altered response to dacarbazine by murine melanoma cells cultured in type I collagen gel.
    Archives of dermatological research, 1990, Volume: 282, Issue:4

    Topics: Animals; Cell Division; Collagen; Dacarbazine; Gels; Melanoma, Experimental; Mice; Tretinoin; Tumor Cells, Cultured

1990
Antitumor efficacy of interleukin-2 alone and in combination with adriamycin and dacarbazine in murine solid tumor systems.
    Cancer research, 1990, Sep-15, Volume: 50, Issue:18

    Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Dacarbazine; Doxorubicin; Female; Interleukin-2; Male; Mammary Neoplasms, Experimental; Melanoma, Experimental; Mice; Mice, Inbred Strains; Neoplasms, Experimental

1990
Antitumor activity and pharmacokinetics in mice of 8-carbamoyl-3-methyl-imidazo[5,1-d]-1,2,3,5-tetrazin-4(3H)-one (CCRG 81045; M & B 39831), a novel drug with potential as an alternative to dacarbazine.
    Cancer research, 1987, Nov-15, Volume: 47, Issue:22

    Topics: Animals; Antineoplastic Agents; Dacarbazine; Imidazoles; Lung Neoplasms; Male; Melanoma, Experimental; Mice; Mice, Inbred BALB C; Mice, Inbred CBA; Mice, Inbred DBA; Mice, Inbred Strains; Neoplasms, Experimental; Plasmacytoma; Sarcoma, Experimental; Species Specificity; Temozolomide

1987