dacarbazine and Angiogenesis, Pathologic

dacarbazine has been researched along with Angiogenesis, Pathologic in 55 studies

Research

Studies (55)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	4 (7.27)	18.2507
2000's	15 (27.27)	29.6817
2010's	36 (65.45)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Balcer, M; Belmans, J; Bouleti, C; De Vleeschouwer, S; Dejaegher, J; Georgieva, PB; Gerhardt, H; Mathivet, T; Matsumoto, K; Mazzone, M; Phng, LK; Sciot, R; Stanchi, F; Stockmann, C; Van Woensel, M; Verschuere, T	1
Abeysekera, IR; Hai, L; Huang, Y; Li, J; Li, T; Liu, P; Ma, H; Tao, Z; Tong, L; Xie, Y; Yang, X; Yi, L; Yu, S; Yuan, F	1
Ekielski, A; Iqbal, Z; Jaggi, M; Mishra, H; Mishra, PK; Talegaonkar, S	1
Brancati, CIFO; Calastri, MCJ; Ferraz Filho, JRL; Godoy, MF; Gregório, ML; Hatori, G; Lancelloti, CLP; Neiva, CM; Rodrigues Junior, ACP; Rodrigues, NLTO; Souza, DRS; Tognola, WA; Zanovelo, EM	1
Banerjee, S; Bhattacharyya, S; Biswas, N; Majumder, B; Mitra, D; Murmu, N; Mustafi, SM; Ray, S	1
Chen, TC; Fayngor, RA; Hofman, FM; Jhaveri, N; Marín-Ramos, NI; Thein, TZ	1
Ameratunga, M; Grant, R; Khasraw, M; Pavlakis, N; Simes, J; Wheeler, H	1
Barboriak, DP; Bokstein, F; Boxerman, JL; Gilbert, MR; McKinstry, RC; Ratai, EM; Safriel, Y; Snyder, BS; Sorensen, AG; Zhang, Z	1
Blakeley, JO; Brem, H; Grossman, R; Khan, U; Kim, E; Pathak, AP; Rudek, MA; Tyler, B; Zadnik, P	1
Bozzi, F; Casali, PG; Cominetti, D; Gronchi, A; Libertini, M; Messina, A; Morosi, C; Negri, T; Palassini, E; Pilotti, S; Stacchiotti, S; Tamborini, E; Tortoreto, M; Zaffaroni, N	1
Alexandru, D; Bigner, D; Bota, DA; Friedman, HS; Keir, ST; Vredenburgh, J	1
Li, XQ; Li, Y; Liu, H; Ouyang, ZG; Shang, Y; Zhang, SH; Zhen, YS	1
Cusimano, MD; Di Ieva, A; Kovacs, K; Rotondo, F; Syro, LV	1
Chen, Q; Jiang, BH; Jiang, C; Jiang, T; Kang, C; Li, C; Li, H; Liu, LZ; Liu, N; Liu, X; Qian, X; Shi, Z; Wang, L; Wang, X; You, Y	1
Ameratunga, MS; Grant, R; Khasraw, M; Pavlakis, N; Wheeler, H	1
Bendszus, M; Blaes, J; Heiland, S; Hertenstein, A; Jestaedt, L; Kessler, T; Milford, D; Osswald, M; Pfenning, PN; Platten, M; Rübmann, P; Ruiz de Almodóvar, C; Sahm, F; Urban, S; von Deimling, A; Weiler, M; Wick, A; Wick, W; Winkler, F	1
Boucard, C; Chinot, O; Delfino, C; Denicolai, E; Figarella-Branger, D; Graillon, T; Metellus, P; Nanni, I; Ouafik, L; Padovani, L; Tabouret, E; Tchoghandjian, A	1
Brawanski, KR; Freyschlag, CF; Grams, AE; Kerschbaumer, J; Nowosielski, M; Petr, O; Pinggera, D; Schmidt, FA; Seiz, M; Thomé, C; Tuettenberg, J	1
Anantha, M; Backstrom, I; Bally, MB; Chu, F; Kalra, J; Masin, D; Strutt, D; Verreault, M; Walker, D; Waterhouse, D; Wehbe, M; Yapp, DT	1
Buchfelder, M; Eyüpoglu, IY; Fan, Z; Ghoochani, A; Hock, S; Savaskan, NE; Sehm, T; Yakubov, E	1
Cai, P; Dahmane, N; Fan, Y; Gong, Y; Huang, M; Kim, HJ; Koumenis, C; Li, C; Liu, T; Ma, P; Mitteer, RA; O'Rourke, DM; Roccograndi, L; Yeo, E; Zhang, D; Zhang, L; Zhang, Z; Zhao, B	1
Gramatzki, D; Roth, P; Seystahl, K; Weller, M	1
Beppu, T; Kato, K; Ogasawara, K; Sasaki, M; Sasaki, T; Sato, Y; Terasaki, K; Tomabechi, M	1
Alsop, DC; Callahan, A; Giarusso, B; O'Loughlin, L; Timmons, J; Wong, ET	1
De Nève, N; Dehoux, M; Dewelle, J; Gaussin, JF; Kiss, R; Le Mercier, M; Lefranc, F; Mathieu, V	1
Battastini, AM; Bernardi, A; Braganhol, E; Edelweiss, MI; Figueiró, F; Guterres, SS; Jäger, E; Pohlmann, AR	1
Dehais, C; Laigle-Donadey, F; Mazeron, JJ; Sanson, M	1
Chen, TC; Golden, EB; Hofman, FM; Pen, L; Schönthal, AH; Sivakumar, W; Virrey, JJ; Wang, W	1
Brockmann, MA; Hermes, P; Kohlhof, P; Neumaier-Probst, E; Schmieder, K; Seiz, M; Tuettenberg, J; Vajkoczy, P; VON Deimling, A	1
Abdulkarim, B; Aghi, M; Chahal, M; Christensen, JG; Famulski, K; Graham, K; Jacques, A; Lesniak, D; Murray, D; Sabri, S; Xu, Y	1
Andrade, LN; Chammas, R; de Oliveira, SI; Fernandes, PD; Jancar, S; Nonogaki, S; Onuchic, AC; Pinheiro, MC; Rohde, CB	1
Cawkwell, L; Little, SJ; Maraveyas, A; Murray, A; Stanley, P	1
Liu, JM; Tang, GS; Wang, Y; Yue, ZJ; Zhang, H; Zhang, YH	1
Brem, S; Wong, ET	1
Agnihotri, S; Cairns, R; Guha, A; Hawkins, C; Micallef, J; Mukherjee, J; Sabha, N; Wolf, A	1
Chen, J; Huang, Y; Li, Z; Liu, P; Ren, J; Wu, G; Zhang, C; Zhang, R; Zhu, F	1
Chakraborty, G; Kumar, S; Kundu, GC; Mishra, R; Patil, TV	1
Chen, TC; Cho, HY; Goldkorn, A; Hofman, FM; Jhaveri, N; Lee, DJ; Leong, MN; Louie, SG; Petasis, NA; Schönthal, AH; Torres, S; Tseng, J; Wang, W; Xu, T	1
Bagriacik, EU; Baykara, M; Benekli, M; Buyukberber, S; Coskun, U; Demirci, U; Ozet, A; Uslu, K; Yaman, M	1
Cuellar, S; Popa, AM; Radhakrishnan, L; Valla, K; Villano, JL	1
Achberger, S; Aldrich, W; Borden, EC; Grane, R; Singh, AD; Triozzi, PL	1
Amiri, KI; Horton, LW; LaFleur, BJ; Richmond, A; Sosman, JA	1
Erber, R; Grobholz, R; Korn, T; Tuettenberg, J; Vajkoczy, P; Wenz, F	1
Kiss, R; Mathieu, V; Mijatovic, T; van Damme, M	1
Jeon, HJ; Kim, H; Kim, JH; Kim, JS; Kim, JT; Kim, MH; Kim, YJ; Lee, DS; Nam, DH; Park, SY; Shin, T; Son, MJ; Song, HS	1
Eoh, W; Kang, CM; Kim, JS; Kim, JT; Kim, MH; Ko, KW; Kong, DS; Lee, DS; Nam, DH; Shin, HJ; Son, MJ; Song, HS	1
Claes, A; Heerschap, A; Jeuken, J; Leenders, WP; Maass, C; Wesseling, P	1
Gallo, JM; Guo, P; Zhou, Q	1
Baumgart, U; Bogdahn, U; Hau, P; Hirschmann, B; Kunz-Schughart, L; Muhleisen, H; Reichle, A; Ruemmele, P; Steinbrecher, A; Weimann, E	1
Kiss, R; Lefranc, F; Mijatovic, T	1
Bontempi, G; Decaestecker, C; Haibe-Kains, B; Kiss, R; Le Mercier, M; Lefranc, F; Mathieu, V; Mijatovic, T	1
Devineni, D; Gallo, JM; Klein-Szanto, A	1
Burris, HA; Eckhardt, SG; Rodriguez, GI; Sharma, S; Valley, A; Weiss, GR	1
Fei, ZL; Gallo, JM; Klein-Szanto, A; Ma, J	1
Burton, E; Prados, M	1

Reviews

7 review(s) available for dacarbazine and Angiogenesis, Pathologic

Article	Year
Anti-angiogenic therapy for high-grade glioma. The Cochrane database of systematic reviews, 2018, 11-22, Volume: 11 Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bevacizumab; Brain Neoplasms; Camptothecin; Dacarbazine; Glioblastoma; Humans; Hypertension; Irinotecan; Lomustine; Neoplasm Recurrence, Local; Neovascularization, Pathologic; Progression-Free Survival; Proteinuria; Randomized Controlled Trials as Topic; Snake Venoms; Temozolomide	2018
Aggressive pituitary adenomas--diagnosis and emerging treatments. Nature reviews. Endocrinology, 2014, Volume: 10, Issue:7 Topics: Adenoma; Biomarkers, Tumor; Dacarbazine; Humans; Ki-67 Antigen; Neoplasm Invasiveness; Neovascularization, Pathologic; Pituitary Neoplasms; Temozolomide; Tumor Suppressor Protein p53	2014
Antiangiogenic therapy for high-grade glioma. The Cochrane database of systematic reviews, 2014, Sep-22, Issue:9 Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bevacizumab; Brain Neoplasms; Camptothecin; Dacarbazine; Glioblastoma; Humans; Hypertension; Irinotecan; Lomustine; Neoplasm Recurrence, Local; Neovascularization, Pathologic; Proteinuria; Randomized Controlled Trials as Topic; Snake Venoms; Temozolomide	2014
Pharmacotherapies for the treatment of glioblastoma - current evidence and perspectives. Expert opinion on pharmacotherapy, 2016, Volume: 17, Issue:9 Topics: Bevacizumab; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Glioblastoma; Humans; Neovascularization, Pathologic; Snake Venoms; Temozolomide	2016
[Association of radiotherapy and chemotherapy-targeted therapies in glioblastomas]. Bulletin du cancer, 2009, Volume: 96, Issue:3 Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Alkylating; Bevacizumab; Brain Neoplasms; Camptothecin; Combined Modality Therapy; Dacarbazine; Glioblastoma; Humans; Irinotecan; Neovascularization, Pathologic; Temozolomide; Vascular Endothelial Growth Factor A	2009
New anticancer agents. Cancer chemotherapy and biological response modifiers, 1997, Volume: 17 Topics: Animals; Antineoplastic Agents; Dacarbazine; Humans; Lactones; Macrolides; Neovascularization, Pathologic; Suramin; Temozolomide; Thymidylate Synthase; Tirapazamine; Triazines; Uracil	1997
New chemotherapy options for the treatment of malignant gliomas. Current opinion in oncology, 1999, Volume: 11, Issue:3 Topics: Adult; Antineoplastic Agents; Brain Neoplasms; Camptothecin; Clinical Trials as Topic; Dacarbazine; Enzyme Inhibitors; Glioma; Humans; Irinotecan; Neovascularization, Pathologic; Oligodendroglioma; Protease Inhibitors; Signal Transduction; Temozolomide; Thalidomide	1999

Trials

4 trial(s) available for dacarbazine and Angiogenesis, Pathologic

Article	Year
Magnetic resonance spectroscopy as an early indicator of response to anti-angiogenic therapy in patients with recurrent glioblastoma: RTOG 0625/ACRIN 6677. Neuro-oncology, 2013, Volume: 15, Issue:7 Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Bevacizumab; Biomarkers, Tumor; Brain Neoplasms; Camptothecin; Choline; Creatine; Dacarbazine; Feasibility Studies; Follow-Up Studies; Glioblastoma; Humans; Irinotecan; Magnetic Resonance Spectroscopy; Neoplasm Recurrence, Local; Neovascularization, Pathologic; Prognosis; Prospective Studies; Survival Rate; Temozolomide	2013
Phase I study of low-dose metronomic temozolomide for recurrent malignant gliomas. BMC cancer, 2016, 11-22, Volume: 16, Issue:1 Topics: Administration, Metronomic; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biomarkers; Dacarbazine; Female; Glioma; Humans; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Middle Aged; Neoplasm Grading; Neoplasm Recurrence, Local; Neoplasm Staging; Neovascularization, Pathologic; Survival Analysis; Temozolomide; Treatment Outcome	2016
The association of blood angioregulatory microRNA levels with circulating endothelial cells and angiogenic proteins in patients receiving dacarbazine and interferon. Journal of translational medicine, 2012, Dec-05, Volume: 10 Topics: Angiogenic Proteins; Cell Movement; Dacarbazine; Endothelial Cells; Humans; Interferon alpha-2; Interferon-alpha; Melanoma; MicroRNAs; Neovascularization, Pathologic; Recombinant Proteins; Uveal Neoplasms	2012
Low-dose chemotherapy in combination with COX-2 inhibitors and PPAR-gamma agonists in recurrent high-grade gliomas - a phase II study. Oncology, 2007, Volume: 73, Issue:1-2 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; Capecitabine; Cyclooxygenase 2 Inhibitors; Dacarbazine; Deoxycytidine; Drug Administration Schedule; Edema; Efferent Pathways; Erythema; Female; Fluorouracil; Gene Expression Regulation, Neoplastic; Glioblastoma; Glioma; Humans; Immunohistochemistry; Lactones; Male; Middle Aged; Neoplasm Recurrence, Local; Neovascularization, Pathologic; Pioglitazone; PPAR gamma; Predictive Value of Tests; Quality of Life; Sulfones; Temozolomide; Thiazolidinediones; Treatment Outcome	2007

Other Studies

44 other study(ies) available for dacarbazine and Angiogenesis, Pathologic

Article	Year
Dynamic stroma reorganization drives blood vessel dysmorphia during glioma growth. EMBO molecular medicine, 2017, Volume: 9, Issue:12 Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents, Alkylating; Blood Vessels; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Disease Models, Animal; Female; Glioma; Humans; Macrophage Colony-Stimulating Factor; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neovascularization, Pathologic; Phenotype; Proto-Oncogene Proteins c-sis; Temozolomide; Vascular Endothelial Growth Factor A	2017
Tumour cell dormancy as a contributor to the reduced survival of GBM patients who received standard therapy. Oncology reports, 2018, Volume: 40, Issue:1 Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Cell Movement; Cell Proliferation; Combined Modality Therapy; Dacarbazine; Disease-Free Survival; Female; Ferritins; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Male; Middle Aged; Neovascularization, Pathologic; Oxidoreductases; Temozolomide; Transcription Factor CHOP; Young Adult	2018
Functionalized nanoliposomes loaded with anti survivin and anti angiogenic agents to enhance the activity of chemotherapy against melanoma by 4-pronged action. Medical hypotheses, 2018, Volume: 116 Topics: Angiogenesis Inhibitors; Antineoplastic Agents; Cell Proliferation; Dacarbazine; Female; Fibroblast Growth Factor 2; Humans; Hyaluronan Receptors; Inhibitor of Apoptosis Proteins; Liposomes; Male; Melanoma; Models, Theoretical; Nanoparticles; Neovascularization, Pathologic; Skin Neoplasms; Survivin; Vascular Endothelial Growth Factor A	2018
Genetic variants related to angiogenesis and apoptosis in patients with glioma. Arquivos de neuro-psiquiatria, 2018, Volume: 76, Issue:6 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Child; Child, Preschool; Combined Modality Therapy; Dacarbazine; Female; Genotype; Glioma; Humans; Infant; Kaplan-Meier Estimate; Life Style; Male; Middle Aged; Neovascularization, Pathologic; Polymorphism, Genetic; Real-Time Polymerase Chain Reaction; Temozolomide; Young Adult	2018
Reversing effect of Lupeol on vasculogenic mimicry in murine melanoma progression. Microvascular research, 2019, Volume: 121 Topics: AC133 Antigen; Angiogenesis Inhibitors; Animals; Antigens, CD; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Biological Mimicry; Cadherins; Dacarbazine; Disease Progression; Drug Resistance, Neoplasm; Endothelial Progenitor Cells; Male; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Neoplastic Stem Cells; Neovascularization, Pathologic; Pentacyclic Triterpenes; Phenotype; Platelet Endothelial Cell Adhesion Molecule-1; Tumor Burden	2019
NEO212, a conjugate of temozolomide and perillyl alcohol, blocks the endothelial-to-mesenchymal transition in tumor-associated brain endothelial cells in glioblastoma. Cancer letters, 2019, 02-01, Volume: 442 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Coculture Techniques; Dacarbazine; Endothelial Cells; Epithelial-Mesenchymal Transition; Glioblastoma; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice, Nude; Neoplasm Invasiveness; Neovascularization, Pathologic; Receptors, Notch; Signal Transduction; Transforming Growth Factor beta; Xenograft Model Antitumor Assays	2019
Microdialysis measurement of intratumoral temozolomide concentration after cediranib, a pan-VEGF receptor tyrosine kinase inhibitor, in a U87 glioma model. Cancer chemotherapy and pharmacology, 2013, Volume: 72, Issue:1 Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barrier; Cerebral Ventricle Neoplasms; Cerebral Ventricles; Dacarbazine; Drug Synergism; Extracellular Fluid; Glioma; Humans; Male; Microdialysis; Neovascularization, Pathologic; Protein Kinase Inhibitors; Quinazolines; Rats; Rats, Nude; Receptors, Vascular Endothelial Growth Factor; Temozolomide; Xenograft Model Antitumor Assays	2013
Dacarbazine in solitary fibrous tumor: a case series analysis and preclinical evidence vis-a-vis temozolomide and antiangiogenics. Clinical cancer research : an official journal of the American Association for Cancer Research, 2013, Sep-15, Volume: 19, Issue:18 Topics: Adult; Aged; Animals; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Dacarbazine; Female; Follow-Up Studies; Humans; Indazoles; Indoles; Male; Mice; Mice, SCID; Middle Aged; Neoplasm Staging; Neovascularization, Pathologic; Prognosis; Pyrimidines; Pyrroles; Retrospective Studies; Solitary Fibrous Tumors; Sulfonamides; Sunitinib; Temozolomide; Xenograft Model Antitumor Assays	2013
Proteasome inhibition with bortezomib induces cell death in GBM stem-like cells and temozolomide-resistant glioma cell lines, but stimulates GBM stem-like cells' VEGF production and angiogenesis. Journal of neurosurgery, 2013, Volume: 119, Issue:6 Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Apoptosis; Bevacizumab; Boronic Acids; Bortezomib; Caspase 3; Cell Line, Tumor; Dacarbazine; Drug Resistance, Neoplasm; Drug Therapy, Combination; Glioblastoma; Glioma; Humans; Male; Mice; Mice, Inbred BALB C; Neoplastic Stem Cells; Neovascularization, Pathologic; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Pyrazines; Temozolomide; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays	2013
Synergistic inhibition of angiogenesis and glioma cell-induced angiogenesis by the combination of temozolomide and enediyne antibiotic lidamycin. Cancer biology & therapy, 2014, Volume: 15, Issue:4 Topics: Aminoglycosides; Angiogenesis Inhibitors; Animals; Anti-Bacterial Agents; Apoptosis; Brain; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dacarbazine; Drug Synergism; Endothelial Cells; Enediynes; Glioma; Heterografts; Humans; Male; Mice, Nude; Neovascularization, Pathologic; Rats; Temozolomide; Vascular Endothelial Growth Factor A	2014
MiR-124 governs glioma growth and angiogenesis and enhances chemosensitivity by targeting R-Ras and N-Ras. Neuro-oncology, 2014, Volume: 16, Issue:10 Topics: Animals; Apoptosis; Brain; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Dacarbazine; Genes, ras; Glioma; Humans; Male; Mice; Mice, Nude; MicroRNAs; Neoplasm Invasiveness; Neovascularization, Pathologic; ras Proteins; Signal Transduction; Temozolomide	2014
Glioma cell VEGFR-2 confers resistance to chemotherapeutic and antiangiogenic treatments in PTEN-deficient glioblastoma. Oncotarget, 2015, Oct-13, Volume: 6, Issue:31 Topics: Angiogenesis Inhibitors; Animals; Bevacizumab; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dacarbazine; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Glioma; Humans; Kaplan-Meier Estimate; Mice, Nude; Neoplasm Invasiveness; Neovascularization, Pathologic; PTEN Phosphohydrolase; Signal Transduction; Temozolomide; Time Factors; Transfection; Tumor Burden; Vascular Endothelial Growth Factor Receptor-2; Xenograft Model Antitumor Assays	2015
Recurrence of glioblastoma after radio-chemotherapy is associated with an angiogenic switch to the CXCL12-CXCR4 pathway. Oncotarget, 2015, May-10, Volume: 6, Issue:13 Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Benzylamines; Brain Neoplasms; Chemokine CXCL12; Chemoradiotherapy; Child; Child, Preschool; Cyclams; Dacarbazine; Disease Progression; Disease-Free Survival; Female; Gene Expression Profiling; Glioblastoma; Heterocyclic Compounds; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; Kaplan-Meier Estimate; Male; Middle Aged; Neoplasm Recurrence, Local; Neovascularization, Pathologic; Proportional Hazards Models; Real-Time Polymerase Chain Reaction; Receptors, CXCR4; Retrospective Studies; Signal Transduction; Temozolomide; Time Factors; Tissue Culture Techniques; Treatment Outcome; Vascular Endothelial Growth Factor Receptor-2; Young Adult	2015
Dual Anti-angiogenic Chemotherapy with Temozolomide and Celecoxib in Selected Patients with Malignant Glioma Not Eligible for Standard Treatment. Anticancer research, 2015, Volume: 35, Issue:9 Topics: Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Celecoxib; Dacarbazine; Disease Progression; Dose-Response Relationship, Drug; Female; Glioma; Humans; Karnofsky Performance Status; Magnetic Resonance Imaging; Male; Middle Aged; Neovascularization, Pathologic; Temozolomide; Time Factors; Tumor Burden	2015
Determination of an optimal dosing schedule for combining Irinophore C™ and temozolomide in an orthotopic model of glioblastoma. Journal of controlled release : official journal of the Controlled Release Society, 2015, Dec-28, Volume: 220, Issue:Pt A Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Brain Neoplasms; Camptothecin; Dacarbazine; Drug Administration Schedule; Drug Compounding; Glioblastoma; Humans; Irinotecan; Liposomes; Mice, Inbred NOD; Mice, SCID; Neovascularization, Pathologic; Temozolomide; Time Factors; Tumor Burden; Xenograft Model Antitumor Assays	2015
A versatile ex vivo technique for assaying tumor angiogenesis and microglia in the brain. Oncotarget, 2016, Jan-12, Volume: 7, Issue:2 Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Dacarbazine; Glioma; Green Fluorescent Proteins; Humans; Mice, Transgenic; Microglia; Microscopy, Confocal; Microscopy, Fluorescence; Neovascularization, Pathologic; Organ Culture Techniques; Rats, Wistar; Reproducibility of Results; Temozolomide; Tumor Microenvironment	2016
c-Met-mediated endothelial plasticity drives aberrant vascularization and chemoresistance in glioblastoma. The Journal of clinical investigation, 2016, 05-02, Volume: 126, Issue:5 Topics: Animals; Cell Hypoxia; Cell Movement; Cell Proliferation; Dacarbazine; Drug Resistance, Neoplasm; Endothelial Cells; Female; Glioblastoma; Humans; Male; Matrix Metalloproteinase 14; Mice; Mice, Knockout; Neovascularization, Pathologic; Proto-Oncogene Protein c-ets-1; Proto-Oncogene Proteins c-met; Temozolomide	2016
MRI and 11C-methyl-L-methionine PET Differentiate Bevacizumab True Responders After Initiating Therapy for Recurrent Glioblastoma. Clinical nuclear medicine, 2016, Volume: 41, Issue:11 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Dacarbazine; Disease-Free Survival; Female; Glioblastoma; Humans; Magnetic Resonance Imaging; Male; Methionine; Middle Aged; Multimodal Imaging; Neoplasm Recurrence, Local; Neovascularization, Pathologic; Positron-Emission Tomography; Prognosis; Temozolomide; Treatment Outcome; Young Adult	2016
Combining bevacizumab with temozolomide increases the antitumor efficacy of temozolomide in a human glioblastoma orthotopic xenograft model. Neoplasia (New York, N.Y.), 2008, Volume: 10, Issue:12 Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Dacarbazine; Endothelium, Vascular; Female; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Neovascularization, Pathologic; Temozolomide	2008
Indomethacin-loaded nanocapsules treatment reduces in vivo glioblastoma growth in a rat glioma model. Cancer letters, 2009, Aug-18, Volume: 281, Issue:1 Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Body Weight; Cell Division; Cell Line, Tumor; Corpus Striatum; Dacarbazine; Drug Evaluation, Preclinical; Glioma; Indomethacin; Injections, Intraperitoneal; Male; Nanocapsules; Neovascularization, Pathologic; Random Allocation; Rats; Rats, Wistar; Supratentorial Neoplasms; Temozolomide; Tumor Burden	2009
Glioma-associated endothelial cells are chemoresistant to temozolomide. Journal of neuro-oncology, 2009, Volume: 95, Issue:1 Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Death; Cell Movement; Cell Proliferation; Cell Survival; Dacarbazine; Dose-Response Relationship, Drug; Endothelial Cells; Gene Expression Regulation, Neoplastic; Glioma; Humans; Male; Mice; Neoplasm Transplantation; Neovascularization, Pathologic; Platelet Endothelial Cell Adhesion Molecule-1; Temozolomide; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Cells, Cultured	2009
First experiences with low-dose anti-angiogenic treatment in gliomatosis cerebri with signs of angiogenic activity. Anticancer research, 2009, Volume: 29, Issue:8 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Celecoxib; Cell Proliferation; Cyclooxygenase 2; Dacarbazine; Disease Progression; Dose-Response Relationship, Drug; Female; Humans; Immunoenzyme Techniques; Male; Middle Aged; Neoplasm Staging; Neoplasms, Neuroepithelial; Neovascularization, Pathologic; Prognosis; Pyrazoles; Sulfonamides; Survival Rate; Temozolomide; Vascular Endothelial Growth Factor A	2009
MGMT modulates glioblastoma angiogenesis and response to the tyrosine kinase inhibitor sunitinib. Neuro-oncology, 2010, Volume: 12, Issue:8 Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Combined Chemotherapy Protocols; Blotting, Western; Brain Neoplasms; Cell Line, Tumor; Cell Separation; Combined Modality Therapy; Dacarbazine; DNA Modification Methylases; DNA Repair Enzymes; Drug Resistance, Neoplasm; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Gene Expression; Gene Expression Profiling; Glioblastoma; Humans; Indoles; Mice; Mice, Nude; Neovascularization, Pathologic; Protein Kinase Inhibitors; Pyrroles; Radiotherapy; Reverse Transcriptase Polymerase Chain Reaction; Sunitinib; Temozolomide; Tumor Suppressor Proteins; Xenograft Model Antitumor Assays	2010
Platelet-activating factor receptor (PAF-R)-dependent pathways control tumour growth and tumour response to chemotherapy. BMC cancer, 2010, May-13, Volume: 10 Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Azepines; Carcinoma, Ehrlich Tumor; Caspase 3; Cell Proliferation; Cyclooxygenase 2; Dacarbazine; Dinoprostone; Enzyme-Linked Immunosorbent Assay; Female; Flow Cytometry; Galectin 3; Immunohistochemistry; Macrophages; Male; Melanoma, Experimental; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Neovascularization, Pathologic; Nitric Oxide; Phenotype; Platelet Membrane Glycoproteins; Receptors, G-Protein-Coupled; Signal Transduction; Time Factors; Triazoles; Tumor Burden; Vascular Endothelial Growth Factor A	2010
Sorafenib enhances the in vitro anti-endothelial effects of low dose (metronomic) chemotherapy. Oncology reports, 2010, Volume: 24, Issue:4 Topics: Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Benzenesulfonates; Cell Line, Tumor; Cell Proliferation; Dacarbazine; Drug Administration Schedule; Endothelial Cells; Etoposide; Humans; In Vitro Techniques; Neovascularization, Pathologic; Niacinamide; Paclitaxel; Phenylurea Compounds; Pyridines; Sorafenib; Temozolomide	2010
Temozolomide/PLGA microparticles plus vatalanib inhibits tumor growth and angiogenesis in an orthotopic glioma model. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2010, Volume: 76, Issue:3 Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Dacarbazine; Disease Models, Animal; Drug Delivery Systems; Glioma; Humans; Lactic Acid; Male; Neovascularization, Pathologic; Phthalazines; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Pyridines; Rats; Rats, Sprague-Dawley; Temozolomide; Treatment Outcome	2010
Taming glioblastoma by targeting angiogenesis: 3 years later. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Jan-10, Volume: 29, Issue:2 Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Clinical Trials, Phase II as Topic; Dacarbazine; Glioblastoma; Humans; Neovascularization, Pathologic; Temozolomide	2011
Hexokinase 2 is a key mediator of aerobic glycolysis and promotes tumor growth in human glioblastoma multiforme. The Journal of experimental medicine, 2011, Feb-14, Volume: 208, Issue:2 Topics: Blotting, Western; Cell Line, Tumor; Cell Proliferation; Dacarbazine; DNA Primers; Flow Cytometry; Fluorescent Antibody Technique; Glioblastoma; Glycolysis; Hexokinase; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; Neovascularization, Pathologic; Phosphorylation; Reverse Transcriptase Polymerase Chain Reaction; Temozolomide; Vascular Endothelial Growth Factor A	2011
Combinational therapy of interferon-α and chemotherapy normalizes tumor vasculature by regulating pericytes including the novel marker RGS5 in melanoma. Journal of immunotherapy (Hagerstown, Md. : 1997), 2011, Volume: 34, Issue:3 Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Biomarkers; Blood Vessels; Combined Modality Therapy; Dacarbazine; Down-Regulation; Female; Gene Expression; Interferon-alpha; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Neovascularization, Pathologic; Pericytes; RGS Proteins	2011
Semaphorin 3A suppresses tumor growth and metastasis in mice melanoma model. PloS one, 2012, Volume: 7, Issue:3 Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Western; Case-Control Studies; Cell Adhesion; Cell Movement; Cell Proliferation; Cells, Cultured; Curcumin; Dacarbazine; Human Umbilical Vein Endothelial Cells; Humans; Immunoenzyme Techniques; Liver Neoplasms; Lung Neoplasms; Male; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Neovascularization, Pathologic; Phosphorylation; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Semaphorin-3A; Wound Healing	2012
Perillyl alcohol for the treatment of temozolomide-resistant gliomas. Molecular cancer therapeutics, 2012, Volume: 11, Issue:11 Topics: Administration, Intranasal; Animals; Brain Neoplasms; Cell Death; Cell Line, Tumor; Cell Proliferation; Cytokines; Dacarbazine; Drug Resistance, Neoplasm; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Glioma; Humans; Mice; Monoterpenes; Nelfinavir; Neoplasm Invasiveness; Neovascularization, Pathologic; Pyrazoles; Sulfonamides; Temozolomide; Xenograft Model Antitumor Assays	2012
Prognostic importance of markers for inflammation, angiogenesis and apoptosis in high grade glial tumors during temozolomide and radiotherapy. International immunopharmacology, 2012, Volume: 14, Issue:4 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Apoptosis; Biomarkers, Tumor; Dacarbazine; Female; Glioma; Humans; Inflammation; Male; Middle Aged; Neovascularization, Pathologic; Temozolomide	2012
Bevacizumab-induced oral mucositis in background of cutaneous plaque-type psoriasis. The Annals of pharmacotherapy, 2012, Volume: 46, Issue:11 Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Alkylating; Bevacizumab; Brain Neoplasms; Dacarbazine; Female; Humans; Neovascularization, Pathologic; Psoriasis; Stomatitis; Temozolomide	2012
Augmenting chemosensitivity of malignant melanoma tumors via proteasome inhibition: implication for bortezomib (VELCADE, PS-341) as a therapeutic agent for malignant melanoma. Cancer research, 2004, Jul-15, Volume: 64, Issue:14 Topics: Active Transport, Cell Nucleus; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Boronic Acids; Bortezomib; Cell Division; Cell Line, Tumor; Dacarbazine; Drug Synergism; Female; Gene Expression; Humans; Melanoma; Mice; Mice, Inbred BALB C; Neovascularization, Pathologic; NF-kappa B; Protease Inhibitors; Pyrazines; Temozolomide	2004
Continuous low-dose chemotherapy plus inhibition of cyclooxygenase-2 as an antiangiogenic therapy of glioblastoma multiforme. Journal of cancer research and clinical oncology, 2005, Volume: 131, Issue:1 Topics: Adult; Angiogenesis Inhibitors; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dacarbazine; Disease-Free Survival; Drug Administration Schedule; Female; Glioblastoma; Humans; Immunohistochemistry; Isoenzymes; Lactones; Male; Membrane Proteins; Middle Aged; Neovascularization, Pathologic; Prostaglandin-Endoperoxide Synthases; Sulfones; Survival Analysis; Temozolomide	2005
Gastrin exerts pleiotropic effects on human melanoma cell biology. Neoplasia (New York, N.Y.), 2005, Volume: 7, Issue:10 Topics: Actins; Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Line, Tumor; Cell Movement; Cholecystokinin; Cisplatin; Cytoskeleton; Dacarbazine; DNA Primers; DNA, Complementary; Flow Cytometry; Gastrins; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Immunohistochemistry; Melanoma; Mice; Neoplasm Invasiveness; Neoplasm Transplantation; Neovascularization, Pathologic; Oligonucleotide Array Sequence Analysis; Poly(ADP-ribose) Polymerases; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Time Factors; Wound Healing	2005
Combination treatment with temozolomide and thalidomide inhibits tumor growth and angiogenesis in an orthotopic glioma model. International journal of oncology, 2006, Volume: 28, Issue:1 Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Proliferation; Dacarbazine; Gene Expression Profiling; Glioma; Humans; In Situ Nick-End Labeling; Neovascularization, Pathologic; Rats; Rats, Sprague-Dawley; Temozolomide; Thalidomide; Transplantation, Heterologous	2006
Metronomic treatment of temozolomide inhibits tumor cell growth through reduction of angiogenesis and augmentation of apoptosis in orthotopic models of gliomas. Oncology reports, 2006, Volume: 16, Issue:1 Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Cell Line, Tumor; Dacarbazine; Disease Models, Animal; Glioma; Humans; Male; Mice; Mice, Inbred BALB C; Neoplasms; Neovascularization, Pathologic; Rats; Rats, Sprague-Dawley; Temozolomide	2006
Antiangiogenic compounds interfere with chemotherapy of brain tumors due to vessel normalization. Molecular cancer therapeutics, 2008, Volume: 7, Issue:1 Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blood-Brain Barrier; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Disease Models, Animal; Humans; Mice; Neovascularization, Pathologic; Piperidines; Quinazolines; Temozolomide; Xenograft Model Antitumor Assays	2008
Impact of angiogenesis inhibition by sunitinib on tumor distribution of temozolomide. Clinical cancer research : an official journal of the American Association for Cancer Research, 2008, Mar-01, Volume: 14, Issue:5 Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Alkylating; Blotting, Western; Collagen; Collagen Type IV; Dacarbazine; Drug Combinations; Glioma; Immunoenzyme Techniques; Indoles; Laminin; Male; Mice; Mice, Nude; Neovascularization, Pathologic; Platelet Endothelial Cell Adhesion Molecule-1; Proteoglycans; Pyrroles; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sunitinib; Temozolomide; Tumor Cells, Cultured; Xenograft Model Antitumor Assays	2008
[The sodium pump could constitute a new target to combat glioblastomas]. Bulletin du cancer, 2008, Volume: 95, Issue:3 Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Apoptosis; Autophagy; Brain Neoplasms; Calotropis; Cardenolides; Cell Movement; Cell Proliferation; Combined Modality Therapy; Dacarbazine; Drug Screening Assays, Antitumor; Glioblastoma; Humans; Mice; Neoplasm Invasiveness; Neoplasm Proteins; Neovascularization, Pathologic; Signal Transduction; Sodium-Potassium-Exchanging ATPase; Temozolomide	2008
Knocking down galectin 1 in human hs683 glioblastoma cells impairs both angiogenesis and endoplasmic reticulum stress responses. Journal of neuropathology and experimental neurology, 2008, Volume: 67, Issue:5 Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Down-Regulation; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Endoribonucleases; Female; Galectin 1; Gene Expression Regulation, Neoplastic; Gene Silencing; Genetic Therapy; Glioblastoma; HSP40 Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Humans; Membrane Proteins; Mice; Molecular Chaperones; Neovascularization, Pathologic; Oxidative Stress; Protein Serine-Threonine Kinases; Proteins; RNA Interference; RNA, Small Interfering; Signal Transduction; Temozolomide; Transplantation, Heterologous	2008
Uptake of temozolomide in a rat glioma model in the presence and absence of the angiogenesis inhibitor TNP-470. Cancer research, 1996, May-01, Volume: 56, Issue:9 Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cyclohexanes; Dacarbazine; Factor VIII; Glioma; Microscopy, Confocal; Neoplasm Transplantation; Neovascularization, Pathologic; O-(Chloroacetylcarbamoyl)fumagillol; Rats; Sesquiterpenes; Temozolomide; Tumor Cells, Cultured	1996
Modulation of angiogenesis by human glioma xenograft models that differentially express vascular endothelial growth factor. Clinical & experimental metastasis, 1998, Volume: 16, Issue:6 Topics: Animals; Antineoplastic Agents, Alkylating; Capillaries; Carmustine; Cell Hypoxia; Dacarbazine; DNA, Antisense; Endothelial Growth Factors; Genetic Vectors; Glioma; Humans; Lymphokines; Male; Neoplasm Proteins; Neovascularization, Pathologic; Rats; Rats, Nude; Temozolomide; Transfection; Transplantation, Heterologous; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors	1998