Compounds > dacarbazine

dacarbazine and Acute Liver Injury, Drug-Induced

dacarbazine has been researched along with Acute Liver Injury, Drug-Induced in 46 studies

Research

Studies (46)

TimeframeStudies, this research(%)All Research%
pre-19909 (19.57)18.7374
1990's3 (6.52)18.2507
2000's3 (6.52)29.6817
2010's31 (67.39)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Ding, D; Fang, H; Kelly, R; Liu, Z; Shi, Q; Tong, W1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Efferth, T; Giordano, FA; Krishna, S; Schmiedek, P; Schöttler, U; Wenz, F2
Deitz, AC; Desai, VCA; He, J; Holick, CN; Lanes, S; Quinlan, SC1
Kleiner, DE1
Eslami, A; Jha, KK; Mathur, AD; Wang, H1
Becker, F; Fietkau, R; Hecht, M; Schmidtner, J; Semrau, S1
Egle, A; Greil, R; Grundbichler, M; Hufnagl, C; Magnes, T; Melchardt, T; Moik, M; Strasser, M; Weiss, L1
Kolarović, J; Lalić-Popović, M; Lalošević, D; Mikov, M; Milijašević, B; Stefanović, D; Tomić, Z1
Adeyi, O; Fung, S; Mason, M; Millar, BA1
Balducci, N; Biolato, M; Di Napoli, N; Diletto, B; Grieco, A; Miele, L; Tafuri, MA; Vecchio, FM1
Fukushima, S; Kiyohara, Y; Namikawa, K; Okuyama, R; Otsuka, Y; Shibagaki, N; Tokudome, T; Tsutsumida, A; Uchi, H; Uhara, H; Yamazaki, N1
Baretti, M; Di Tommaso, L; Santoro, A; Simonelli, M1
Lee, TY; Lu, H; Sheng, R; Zhang, C1
Abu Rmeileh, A; Benson, AA; Chen, S; Cohen, J; Daher, S; Khoury, T; Mizrahi, M; Yaari, S1
Hoorens, A; Neyns, B; Stupp, R1
Bedikian, AY; Cain, S; Glass, MR; Homsi, J; Hwu, P; Hwu, WJ; Kim, KB; Papadopoulos, NE; Rudewicz, P; Vernillet, L1
Egawa, T; Horiguchi, M; Kaji, H; Kim, J; Koyanagi, S; Makino, K; Matsunaga, N; Ohdo, S1
Buesa, JM; Carrasco, JA; Casado, A; Cruz, J; Cubedo, R; de Andrés, R; De Juan, A; Fra, J; García-Del-Muro, X; Gómez-España, A; Laínez, N; López-Pousa, A; Martín, J; Martínez-Trufero, J; Maurel, J; Meana, A; Pericay, C; Poveda, A; Rubió, J1
Afzal, P; Campbell, AP; Dixit, S; Hingorani, M1
Bronder, E; Garbe, E; Herbst, H; Kauffmann, W; Klimpel, A; Orzechowski, HD; Sarganas, G; Thomae, M1
Mohammad Alizadeh, A; Zamani, N1
Casini, M; Cavattoni, IM; Cortelazzo, S; Deola, S; Farsad, M; Mian, M; Pescosta, N1
Conjeevaram, HS; Grant, LM; Kleiner, DE; Lee, WM; Vuppalanchi, R1
Hong, YK; Jeun, SS; Kang, JK; Kim, MC; Kim, MK; Lee, KS; Lee, TK; Park, CK; Yang, SH1
Czarnetzki, BM; Macher, E1
Doepfmer, K; Féaux de Lacroix, W; Groth, W; Hauk, H; Runne, U; Wacker, D1
Classen, M; Dancygier, H; Leuschner, U; Milbradt, R; Runne, U1
Caselitz, J; Jänner, M; Voigt, H1
Arseneau, JC; Asbury, RF; Descalzi, ME; Ratcliffe, RL; Rosenthal, SN1
Avilés, A; Díaz-Maqueo, JC; García, EL; Guzmán, R; Talavera, A1
Braun, S; Heine, M; Paschke, R; Usadel, KH1
Bouche, O; Cartier, H; Egreteau, JP; Lambolais, C; Quinio, P; Savry, C1
Colsky, J; Costanza, ME; Cunningham, T; Nathanson, L; Regelson, W; Schoenfeld, D; Sedransk, N; Wolter, J1
Czarnetzki, BM; Frosch, PJ; Gottschalk, I; Grundmann, E; Macher, E1
Lusch, CJ; Mastrangelo, MJ; McClay, E1
Heine, M; Paschke, R1

Reviews

6 review(s) available for dacarbazine and Acute Liver Injury, Drug-Induced

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Recent Advances in the Histopathology of Drug-Induced Liver Injury.
    Surgical pathology clinics, 2018, Volume: 11, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Biopsy; Chemical and Drug Induced Liver Injury; Dacarbazine; Diagnosis, Differential; Dietary Supplements; Hepatitis, Autoimmune; Humans; Immunosuppressive Agents; Liver; Phytotherapy; Temozolomide

2018
Severe cholestatic hepatitis due to temozolomide: an adverse drug effect to keep in mind. Case report and review of literature.
    Medicine, 2015, Volume: 94, Issue:12

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemical and Drug Induced Liver Injury; Cholestasis; Dacarbazine; Fatal Outcome; Glioblastoma; Humans; Male; Temozolomide

2015
Hepatotoxicity by combination treatment of temozolomide, artesunate and Chinese herbs in a glioblastoma multiforme patient: case report review of the literature.
    Archives of toxicology, 2017, Volume: 91, Issue:4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Artemisinins; Artesunate; Chemical and Drug Induced Liver Injury; Chemoradiotherapy; Dacarbazine; Drugs, Chinese Herbal; Female; Glioblastoma; Humans; Temozolomide

2017
Severe sustained cholestatic hepatitis following temozolomide in a patient with glioblastoma multiforme: case study and review of data from the FDA adverse event reporting system.
    Neuro-oncology, 2012, Volume: 14, Issue:5

    Topics: Adverse Drug Reaction Reporting Systems; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemical and Drug Induced Liver Injury; Cholestasis; Dacarbazine; Glioblastoma; Hepatitis; Humans; Male; Middle Aged; Prognosis; Temozolomide; United States; United States Food and Drug Administration

2012
Clinical and histological features of idiosyncratic acute liver injury caused by temozolomide.
    Digestive diseases and sciences, 2013, Volume: 58, Issue:5

    Topics: Aged; Antineoplastic Agents, Alkylating; Chemical and Drug Induced Liver Injury; Dacarbazine; Female; Humans; Liver; Male; Middle Aged; Temozolomide

2013

Trials

6 trial(s) available for dacarbazine and Acute Liver Injury, Drug-Induced

ArticleYear
Phase II study of the immune-checkpoint inhibitor ipilimumab plus dacarbazine in Japanese patients with previously untreated, unresectable or metastatic melanoma.
    Cancer chemotherapy and pharmacology, 2015, Volume: 76, Issue:5

    Topics: Adult; Aged; Alanine Transaminase; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; CTLA-4 Antigen; Dacarbazine; Disease Progression; Disease-Free Survival; Drug Administration Schedule; Drug Eruptions; Endocrine System Diseases; Female; Humans; Immunosuppressive Agents; Ipilimumab; Japan; Kaplan-Meier Estimate; Maintenance Chemotherapy; Male; Melanoma; Middle Aged; Neoplasm Proteins; Remission Induction; Treatment Outcome

2015
A phase IB trial of intravenous INO-1001 plus oral temozolomide in subjects with unresectable stage-III or IV melanoma.
    Cancer investigation, 2009, Volume: 27, Issue:7

    Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Chemical and Drug Induced Liver Injury; Dacarbazine; DNA Mismatch Repair; Drug Administration Schedule; Female; Humans; Indoles; Infusions, Intravenous; Male; Melanoma; Middle Aged; Neoplasm Proteins; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Temozolomide

2009
Randomized phase II study comparing gemcitabine plus dacarbazine versus dacarbazine alone in patients with previously treated soft tissue sarcoma: a Spanish Group for Research on Sarcomas study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Jun-20, Volume: 29, Issue:18

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chemical and Drug Induced Liver Injury; Dacarbazine; Deoxycytidine; Disease-Free Survival; Drug Administration Schedule; Female; Gastrointestinal Diseases; Gemcitabine; Hematologic Diseases; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Proportional Hazards Models; Salvage Therapy; Sarcoma; Soft Tissue Neoplasms; Spain; Treatment Outcome; Young Adult

2011
Temozolomide chemotherapy in patients with recurrent malignant gliomas.
    Journal of Korean medical science, 2006, Volume: 21, Issue:4

    Topics: Administration, Oral; Adolescent; Adult; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Chemical and Drug Induced Liver Injury; Combined Modality Therapy; Dacarbazine; Drug Administration Schedule; Female; Glioma; Humans; Leukopenia; Magnetic Resonance Imaging; Male; Middle Aged; Nausea; Neoplasm Recurrence, Local; Survival Analysis; Temozolomide; Treatment Outcome; Vomiting

2006
Randomized study for the treatment of adult advanced Hodgkin's disease: epirubicin, vinblastine, bleomycin, and dacarbazine (EVBD) versus mitoxantrone, vinblastine, bleomycin, and dacarbazine (MVBD).
    Medical and pediatric oncology, 1994, Volume: 22, Issue:3

    Topics: Actuarial Analysis; Adolescent; Adult; Agranulocytosis; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chemical and Drug Induced Liver Injury; Dacarbazine; Epirubicin; Female; Hodgkin Disease; Humans; Male; Middle Aged; Mitoxantrone; Prospective Studies; Thrombocytopenia; Treatment Outcome; Ventricular Function, Left; Vinblastine

1994
Results with methyl-CCNU and DTIC in metastatic melanoma.
    Cancer, 1977, Volume: 40, Issue:3

    Topics: Brain Neoplasms; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Dacarbazine; Drug Therapy, Combination; Female; Humans; Liver Neoplasms; Male; Melanoma; Neoplasm Metastasis; Nitrosourea Compounds; Prognosis; Remission, Spontaneous; Semustine; Thrombocytopenia; Time Factors; Triazenes

1977

Other Studies

34 other study(ies) available for dacarbazine and Acute Liver Injury, Drug-Induced

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
    PLoS computational biology, 2011, Volume: 7, Issue:12

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Databases, Factual; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Models, Biological; Predictive Value of Tests

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Answer to the comment of Hai Lu et al. regarding "Hepatotoxicity by combination treatment of temozolomide, artesunate and Chinese herbs in a glioblastoma multiforme patient: case report and review of the literature. Arch Toxicol (2016)".
    Archives of toxicology, 2017, Volume: 91, Issue:6

    Topics: Artemisinins; Artesunate; Brain Neoplasms; Chemical and Drug Induced Liver Injury; Dacarbazine; Glioblastoma; Humans; Temozolomide

2017
Risk of severe acute liver injury among patients with brain cancer treated with temozolomide: a nested case-control study using the healthcore integrated research database.
    Journal of neuro-oncology, 2017, Volume: 134, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Case-Control Studies; Chemical and Drug Induced Liver Injury; Cohort Studies; Dacarbazine; Databases, Factual; Delivery of Health Care; Disease-Free Survival; Female; Glioblastoma; Humans; Male; Middle Aged; Temozolomide; Young Adult

2017
Acute liver failure secondary to ABVD use.
    BMJ case reports, 2018, Jul-30, Volume: 2018

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Brentuximab Vedotin; Chemical and Drug Induced Liver Injury; Dacarbazine; Dose-Response Relationship, Drug; Doxorubicin; Female; Hodgkin Disease; Humans; Immunoconjugates; Syncope; Treatment Outcome; Vinblastine

2018
Temozolomide-induced liver damage. A case report.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2014, Volume: 190, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Chemical and Drug Induced Liver Injury; Dacarbazine; Diagnosis, Differential; Female; Humans; Middle Aged; Temozolomide; Treatment Outcome

2014
Liver toxicity during temozolomide chemotherapy caused by Chinese herbs.
    BMC complementary and alternative medicine, 2014, Mar-30, Volume: 14

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Alkylating; Bevacizumab; Brain Neoplasms; Camptothecin; Chemical and Drug Induced Liver Injury; Combined Modality Therapy; Dacarbazine; Disease Progression; Drugs, Chinese Herbal; Female; Glioblastoma; Herb-Drug Interactions; Humans; Irinotecan; Liver; Middle Aged; Phytotherapy; Temozolomide

2014
Acute toxic effects of single dose dacarbazine: hematological and histological changes in an animal model.
    Biotechnic & histochemistry : official publication of the Biological Stain Commission, 2014, Volume: 89, Issue:8

    Topics: Animals; Antineoplastic Agents, Alkylating; Cell Line, Tumor; Chemical and Drug Induced Liver Injury; Cricetinae; Dacarbazine; Dose-Response Relationship, Drug; Fibrosarcoma; Hematologic Diseases; Hepatitis; Humans; Male; Pneumonia; Treatment Outcome

2014
Temozolomide: fatal hepatic failure.
    Prescrire international, 2014, Volume: 23, Issue:152

    Topics: Antineoplastic Agents, Alkylating; Chemical and Drug Induced Liver Injury; Dacarbazine; Humans; Liver Failure; Liver Function Tests; Risk Assessment; Risk Factors; Temozolomide; Time Factors

2014
Vanishing bile duct syndrome in the context of concurrent temozolomide for glioblastoma.
    BMJ case reports, 2014, Nov-28, Volume: 2014

    Topics: Antineoplastic Agents, Alkylating; Biopsy, Needle; Brain Neoplasms; Chemical and Drug Induced Liver Injury; Cholestyramine Resin; Common Bile Duct Diseases; Dacarbazine; Female; Follow-Up Studies; Glioblastoma; Humans; Immunohistochemistry; Jaundice; Liver Function Tests; Middle Aged; Syndrome; Temozolomide; Treatment Outcome; Ursodeoxycholic Acid

2014
Pathological characterization of nivolumab-related liver injury in a patient with glioblastoma.
    Immunotherapy, 2016, Volume: 8, Issue:12

    Topics: Aged; Antibodies, Monoclonal; Antineoplastic Agents; Autoimmunity; Brain Neoplasms; Chemical and Drug Induced Liver Injury; Dacarbazine; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Glioblastoma; Humans; Isocitrate Dehydrogenase; Male; Neoplasm Staging; Nivolumab; Programmed Cell Death 1 Receptor; Temozolomide; Tumor Suppressor Proteins

2016
Comments regarding "Hepatotoxicity by combination treatment of temozolomide, artesunate and Chinese herbs in a glioblastoma multiforme patient: case report review of the literature".
    Archives of toxicology, 2017, Volume: 91, Issue:6

    Topics: Artemisinins; Artesunate; Brain Neoplasms; Chemical and Drug Induced Liver Injury; Dacarbazine; Glioblastoma; Humans; Temozolomide

2017
Acute liver injury induced by levetiracetam and temozolomide co-treatment.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2017, Volume: 49, Issue:3

    Topics: Adult; Aged; Anticonvulsants; Antineoplastic Agents, Alkylating; Brain Neoplasms; Case-Control Studies; Chemical and Drug Induced Liver Injury; Dacarbazine; Drug Therapy, Combination; Female; Humans; Israel; Levetiracetam; Liver Function Tests; Male; Middle Aged; Multivariate Analysis; Piracetam; Regression Analysis; Retrospective Studies; Temozolomide

2017
Valproic acid related idiosyncratic drug induced hepatotoxicity in a glioblastoma patient treated with temozolomide.
    Acta neurologica Belgica, 2008, Volume: 108, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemical and Drug Induced Liver Injury; Chemotherapy, Adjuvant; Cholestasis; Dacarbazine; Glioblastoma; Humans; Liver Failure; Male; Middle Aged; Temozolomide; Valproic Acid

2008
Glucocorticoid-dependent expression of O(6)-methylguanine-DNA methyltransferase gene modulates dacarbazine-induced hepatotoxicity in mice.
    The Journal of pharmacology and experimental therapeutics, 2010, Volume: 333, Issue:3

    Topics: Adrenalectomy; Animals; Antineoplastic Agents; Cells, Cultured; Chemical and Drug Induced Liver Injury; Circadian Rhythm; Corticosterone; Dacarbazine; Dose-Response Relationship, Drug; Glucocorticoids; Hormone Antagonists; Male; Mice; Mice, Inbred ICR; Mifepristone; O(6)-Methylguanine-DNA Methyltransferase; Reverse Transcriptase Polymerase Chain Reaction

2010
Temozolomide induced liver injury.
    Acta neurologica Belgica, 2011, Volume: 111, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemical and Drug Induced Liver Injury; Chemoradiotherapy; Dacarbazine; Female; Glioblastoma; Humans; Middle Aged; Temozolomide

2011
Drug-induced cholestatic hepatitis: how late can it occur even after the cessation of the culpable drug?
    Neuro-oncology, 2012, Volume: 14, Issue:7

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Antineoplastic Agents, Alkylating; Chemical and Drug Induced Liver Injury; Cholestasis; Dacarbazine; Drug Therapy, Combination; Glioblastoma; Humans; Male; Middle Aged; Prognosis; Temozolomide

2012
Bendamustine salvage for the treatment of relapsed Hodgkin's lymphoma after allogeneic bone marrow transplantation.
    Annals of hematology, 2013, Volume: 92, Issue:1

    Topics: Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Bendamustine Hydrochloride; Bleomycin; Bone Marrow Transplantation; Chemical and Drug Induced Liver Injury; Combined Modality Therapy; Cyclophosphamide; Dacarbazine; Deoxycytidine; Doxorubicin; Etoposide; Fatal Outcome; Female; Gemcitabine; Graft vs Host Disease; Hodgkin Disease; Humans; Ifosfamide; Male; Nitrogen Mustard Compounds; Prednisolone; Prednisone; Procarbazine; Recurrence; Reoperation; Rituximab; Salvage Therapy; Transplantation, Autologous; Transplantation, Homologous; Vinblastine; Vincristine; Vinorelbine; Young Adult

2013
DTIC (dacarbazine)-induced hepatic damage. Possible pathogenesis and prevention.
    Archives of dermatological research, 1981, Volume: 270, Issue:3

    Topics: Aged; Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Dacarbazine; Female; gamma-Glutamyltransferase; Humans; Melanoma; Prednisone; Skin Neoplasms

1981
Acute liver dystrophy with thrombosis of hepatic veins: a fatal complication of dacarbazine treatment.
    Cancer treatment reports, 1983, Volume: 67, Issue:9

    Topics: Chemical and Drug Induced Liver Injury; Dacarbazine; Female; Hepatic Veins; Humans; Liver Diseases; Male; Melanoma; Middle Aged; Necrosis; Skin Neoplasms; Thrombosis

1983
Dacarbazine (DTIC)-induced human liver damage light and electron-microscopic findings.
    Hepato-gastroenterology, 1983, Volume: 30, Issue:3

    Topics: Chemical and Drug Induced Liver Injury; Dacarbazine; Humans; Liver; Liver Diseases; Male; Middle Aged

1983
[Veno-occlusive syndrome with acute liver dystrophy following decarbazine therapy of malignant melanoma (author's transl)].
    Klinische Wochenschrift, 1981, Mar-02, Volume: 59, Issue:5

    Topics: Aged; Budd-Chiari Syndrome; Chemical and Drug Induced Liver Injury; Dacarbazine; Hepatic Veins; Humans; Liver; Lymphatic Metastasis; Male; Melanoma; Skin Neoplasms

1981
Hepatic veno-occlusive disease due to DTIC.
    Cancer, 1980, May-15, Volume: 45, Issue:10

    Topics: Budd-Chiari Syndrome; Chemical and Drug Induced Liver Injury; Dacarbazine; Humans; Liver; Male; Melanoma; Middle Aged; Necrosis

1980
Mechanisms of hepatotoxicity caused by dacarbazine in rats.
    Journal of cancer research and clinical oncology, 1993, Volume: 119, Issue:8

    Topics: Alanine Transaminase; Animals; Blood Platelets; Chemical and Drug Induced Liver Injury; Cholinesterases; Dacarbazine; Enzyme Induction; Leukocytes; Liver; Liver Diseases; Microsomes, Liver; Rats; Rats, Sprague-Dawley

1993
Fatal hepatic toxicity of DTIC: a new case.
    Intensive care medicine, 1997, Volume: 23, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Dacarbazine; Fatal Outcome; Female; Humans; Melanoma; Middle Aged

1997
Hepatic failure in a patient treated with dacarbazine (DTIC) for malignant melanoma.
    Journal of cancer research and clinical oncology, 1979, Volume: 95, Issue:3

    Topics: Budd-Chiari Syndrome; Chemical and Drug Induced Liver Injury; Dacarbazine; Drug Hypersensitivity; Eosinophils; Female; Humans; Liver Diseases; Melanoma; Middle Aged; Skin Neoplasms

1979
Allergy-induced hepatic toxicity associated with dacarbazine.
    Cancer treatment reports, 1987, Volume: 71, Issue:2

    Topics: Autopsy; Budd-Chiari Syndrome; Chemical and Drug Induced Liver Injury; Combined Modality Therapy; Dacarbazine; Drug Hypersensitivity; Humans; Laparotomy; Liver Diseases; Male; Melanoma; Middle Aged; Skin Diseases

1987
Pathophysiological aspects of dacarbazine-induced human liver damage.
    Hepato-gastroenterology, 1985, Volume: 32, Issue:6

    Topics: Adult; Budd-Chiari Syndrome; Chemical and Drug Induced Liver Injury; Dacarbazine; Eosinophilia; Female; Humans; Liver

1985