Page last updated: 2024-09-05

dabigatran and Inflammation

dabigatran has been researched along with Inflammation in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's10 (71.43)24.3611
2020's4 (28.57)2.80

Authors

AuthorsStudies
Fu, X; Lei, T; Peng, J; Tang, C1
Kimura, G; Kizawa, Y; Nagamoto, A; Nishimoto, Y; Takahashi, R; Ueda, K; Yoshino, K1
Cadamuro, J; Gruber, S; Haschke-Becher, E; Hoppe, UC; Jirak, P; Lichtenauer, M; Motloch, LJ; Paar, V; Prodinger, C; Wernly, B1
Bihaqi, SW; Grammas, P; Iannucci, J; Sen, A; Vittal Rao, H1
Abd El Fattah, MA; Ahmed, LA; El-Sayeh, BM; Kandil, EA; Sayed, RH1
Abrahams, SR; Divanovic, S; Flick, MJ; Goss, A; Kopec, AK; Luyendyk, JP; Mackman, N; Mullins, ES; Owens, AP; Palumbo, JS; Thornton, S; van Ryn, J; Weiler, H1
Feldmann, K; Fender, AC; Fischer, JW; Gerfer, S; Grandoch, M; Hartwig, S; Kohlmorgen, C; Lehr, S; Nagy, N; Valentin, B1
Biessen, EA; Borissoff, JI; Daemen, MJ; Degen, JL; Esmon, CT; Hackeng, TM; Hamulyák, K; Heeneman, S; Leenders, P; Loubele, ST; Otten, JJ; Soehnlein, O; Spronk, HM; ten Cate, H; van Oerle, R; van Ryn, J; Weiler, H1
Esmon, CT1
Chantrathammachart, P; Hebbel, RP; Key, NS; Mackman, N; Mickelson, J; Monroe, DM; Pawlinski, R; Sparkenbaugh, EM; van Ryn, J1
Flick, MJ; Joshi, N; Kassel, KM; Kopec, AK; Luyendyk, JP; Sullivan, BP; Towery, KL1
Ellinghaus, P; Gerdes, C; Hauenschild, P; Heitmeier, S; Laux, V; Perzborn, E; Summer, H; Visser, M1
Dittmeier, M; Fluri, F; Kleinschnitz, C; Kraft, P; Schuhmann, MK; Wassmuth, K1
Antoniak, S; Bastarache, JA; Beck, MA; Gondouin, B; Mackman, N; Mickelson, J; Monroe, DM; Neidich, SD; Subramaniam, S; Tatsumi, K1

Reviews

1 review(s) available for dabigatran and Inflammation

ArticleYear
Targeting factor Xa and thrombin: impact on coagulation and beyond.
    Thrombosis and haemostasis, 2014, Apr-01, Volume: 111, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Anticoagulants; Atherosclerosis; Benzimidazoles; Blood Coagulation; Clinical Trials, Phase III as Topic; Dabigatran; Drug Evaluation, Preclinical; Factor Xa; Humans; Inflammation; Pyrazoles; Pyridines; Pyridones; Receptors, Proteinase-Activated; Thrombin; Thrombosis

2014

Other Studies

13 other study(ies) available for dabigatran and Inflammation

ArticleYear
Construction of an Antithrombotic and Anti-Inflammatory Polyethersulfone Membrane.
    Macromolecular bioscience, 2023, Volume: 23, Issue:7

    Topics: Anti-Inflammatory Agents; Dabigatran; Fibrinolytic Agents; Humans; Inflammation; Thrombin

2023
[Inhibitory Effects of Dabigatran on Airway Inflammation Induced by Lipopolysaccharide in Mice].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2020, Dec-01, Volume: 140, Issue:12

    Topics: Animals; Antithrombins; Asthma; Biomarkers; Bronchoalveolar Lavage Fluid; Chemokine CXCL1; Dabigatran; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Fluticasone; Inflammation; Inflammation Mediators; Lipopolysaccharides; Male; Mice, Inbred Strains; Osteopontin; Pulmonary Disease, Chronic Obstructive; Tumor Necrosis Factor-alpha

2020
Influence of dabigatran on pro-inflammatory cytokines, growth factors and chemokines - Slowing the vicious circle of coagulation and inflammation.
    Life sciences, 2020, Dec-01, Volume: 262

    Topics: Adult; Antithrombins; Blood Coagulation; Cells, Cultured; Chemokines; Cytokines; Dabigatran; Dose-Response Relationship, Drug; Humans; Inflammation; Intercellular Signaling Peptides and Proteins; Leukocytes, Mononuclear; Ribonuclease, Pancreatic

2020
Thrombin Signaling Contributes to High Glucose-Induced Injury of Human Brain Microvascular Endothelial Cells.
    Journal of Alzheimer's disease : JAD, 2021, Volume: 79, Issue:1

    Topics: Alzheimer Disease; Antithrombins; Brain; Cyclic AMP Response Element-Binding Protein; Dabigatran; Diabetes Mellitus, Type 2; Endothelial Cells; Endothelium, Vascular; Glucose; Humans; Inflammation; Interleukin-6; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Microvessels; NADPH Oxidase 4; Nitric Oxide Synthase Type II; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Thrombin; Tumor Necrosis Factor-alpha; Up-Regulation

2021
Modulatory Role of Nurr1 Activation and Thrombin Inhibition in the Neuroprotective Effects of Dabigatran Etexilate in Rotenone-Induced Parkinson's Disease in Rats.
    Molecular neurobiology, 2018, Volume: 55, Issue:5

    Topics: alpha-Synuclein; Animals; Dabigatran; Dopamine; Dopaminergic Neurons; Inflammation; Male; Neostriatum; Neuroprotective Agents; Nuclear Receptor Subfamily 4, Group A, Member 2; Parkinson Disease; Rats, Wistar; Rotenone; Substantia Nigra; Thrombin

2018
Thrombin promotes diet-induced obesity through fibrin-driven inflammation.
    The Journal of clinical investigation, 2017, Aug-01, Volume: 127, Issue:8

    Topics: Adipose Tissue; Adiposity; Amino Acid Motifs; Animals; Blood Glucose; Body Composition; Body Weight; Coagulants; Dabigatran; Diet, High-Fat; Fatty Liver; Female; Fibrin; Genotype; Homozygote; Inflammation; Liver; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Obesity; Thrombin; Weight Gain

2017
Decreased M1 macrophage polarization in dabigatran-treated Ldlr-deficient mice: Implications for atherosclerosis and adipose tissue inflammation.
    Atherosclerosis, 2019, Volume: 287

    Topics: Adipose Tissue; Animals; Antithrombins; Aorta, Thoracic; Atherosclerosis; Dabigatran; Disease Models, Animal; Female; Flow Cytometry; Immunohistochemistry; Inflammation; Macrophage Activation; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout

2019
Genetic and pharmacological modifications of thrombin formation in apolipoprotein e-deficient mice determine atherosclerosis severity and atherothrombosis onset in a neutrophil-dependent manner.
    PloS one, 2013, Volume: 8, Issue:2

    Topics: Animals; Apolipoproteins E; Atherosclerosis; Benzimidazoles; Blood Coagulation; Dabigatran; Disease Models, Animal; Disease Progression; Female; Hematopoiesis; Inflammation; Mice; Mice, Knockout; Neutrophils; Phenotype; Plaque, Atherosclerotic; Pyridines; Reactive Oxygen Species; Thrombin; Thrombosis

2013
Differential contribution of FXa and thrombin to vascular inflammation in a mouse model of sickle cell disease.
    Blood, 2014, Mar-13, Volume: 123, Issue:11

    Topics: Anemia, Sickle Cell; Animals; Anticoagulants; Antithrombins; Benzimidazoles; beta-Alanine; Bone Marrow Transplantation; Dabigatran; Disease Models, Animal; Factor Xa; Factor Xa Inhibitors; Female; Immunoenzyme Techniques; Inflammation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Morpholines; Receptor, PAR-1; Receptor, PAR-2; Rivaroxaban; Thiophenes; Thrombin; Vascular Diseases

2014
Thrombin inhibition with dabigatran protects against high-fat diet-induced fatty liver disease in mice.
    The Journal of pharmacology and experimental therapeutics, 2014, Volume: 351, Issue:2

    Topics: Alanine Transaminase; Animals; Benzimidazoles; beta-Alanine; Bile Acids and Salts; Dabigatran; Diet, High-Fat; Fatty Liver; Fibrin; Gene Expression; Inflammation; Lipid Metabolism; Liver; Male; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Thrombin; Weight Gain

2014
Expression of pro-inflammatory genes in human endothelial cells: Comparison of rivaroxaban and dabigatran.
    Thrombosis research, 2016, Volume: 142

    Topics: Antithrombins; Dabigatran; Endothelial Cells; Factor Xa Inhibitors; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Lactones; Pyridines; Receptor, PAR-1; Rivaroxaban; Thrombin; Transcriptome

2016
Dabigatran Etexilate Reduces Thrombin-Induced Inflammation and Thrombus Formation in Experimental Ischemic Stroke.
    Current neurovascular research, 2016, Volume: 13, Issue:3

    Topics: Animals; Anticoagulants; Blood Coagulation; Blood-Brain Barrier; Cerebral Hemorrhage; Dabigatran; Disease Models, Animal; Inflammation; Male; Rats, Wistar; Stroke; Thrombin; Thrombosis

2016
Anticoagulation increases alveolar hemorrhage in mice infected with influenza A.
    Physiological reports, 2016, Volume: 4, Issue:24

    Topics: Animals; Anticoagulants; Capillary Permeability; Dabigatran; Hemorrhage; Inflammation; Influenza A Virus, H1N1 Subtype; Male; Mice; Mice, Inbred C57BL; Orthomyxoviridae Infections; Pulmonary Alveoli; Survival Analysis; Warfarin

2016