Page last updated: 2024-09-05

dabigatran and Blood Loss, Surgical

dabigatran has been researched along with Blood Loss, Surgical in 36 studies

Research

Studies (36)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (2.78)	29.6817
2010's	32 (88.89)	24.3611
2020's	3 (8.33)	2.80

Authors

Authors	Studies
Elsaesser, A; Glund, S; Kreuzer, J; Levy, JH; Pollack, CV; Reilly, PA; Sellke, FW; van Ryn, J; Weitz, JI	1
Barequet, IS; Bourla, N; Moisseiev, J; Salomon, O; Tamarin, I; Zehavi-Dorin, T	1
Goya, M; Hirao, K; Kawabata, M; Maeda, S; Sasano, T; Takahashi, Y; Yagishita, A	1
Caprini, JA; Clark, NP; Douketis, J; Kaplovitch, E; Li, N; MacDougall, K; Schulman, S; Spyropoulos, AC; Tafur, AJ	1
Ali, M; Gunasekaran, K; Kaatz, S; Lavender, R; Mahan, CE; Nakhle, A; Paje, DG	1
Chen, HM; Chou, PC; Chua, SK; Lee, CW; Li, YH; Liao, PC; Lin, HJ; Lin, MJ; Tsai, LK; Yang, YP; Yeh, JT	1
Calabria, S; Dondi, L; Forcesi, E; Maggioni, AP; Martini, N; Pedrini, A	1
Andrade, LAP; Andrade, MQS; Andrade, MVS; Bispo, AF; Feitosa, GS; Feitosa-Filho, GS; Freitas, LA	1
Dibiasi, C; Gratz, J; Wiegele, M	1
Castillo, J; de Andrés, J; Ferrandis, R; Gomar, C; Gómez-Luque, A; Hidalgo, F; Llau, JV; Torres, LM	1
Bazargan, A; Douglas, G; McKenzie, JL	1
Kalus, JS	1
John, A; Michel, MS	1
Curnow, J; Joseph, J; McLintock, C; McRae, S; Nandurkar, H; Tran, H; Wood, P; Young, L	1
Awad, NI; Brunetti, L; Juurlink, DN	1
Brueckmann, M; Connolly, SJ; Douketis, JD; Eikelboom, JW; Ezekowitz, MD; Fraessdorf, M; Healey, JS; Noack, H; Oldgren, J; Reilly, P; Spyropoulos, AC; Wallentin, L	1
Chatelain, B; Dincq, AS; Dogné, JM; Douxfils, J; Gourdin, M; Hjemdahl, P; Lessire, S; Mullier, F; Pohanka, A; Rönquist-Nii, Y	1
Pottegård, A; Rasmussen, LE; Viberg, BL	1
Bernstein, R; Dubiel, R; Eikelboom, J; Glund, S; Huisman, MV; Hylek, E; Kam, CW; Kamphuisen, PW; Kreuzer, J; Levy, JH; Pollack, CV; Reilly, PA; Sellke, F; Stangier, J; Steiner, T; Wang, B; Weitz, JI	1
Smith, LL	1
Blum, RA; Lindfield, D	1
Pollack, CV	1
Pasechnik, IN	1
Bischoff, M	1
Sié, P	1
Gerstrøm, G; Nybo, M; Rosenberg, L	1
Caldwell, SH; Intagliata, NM; Maitland, H; Pellitier, S	1
Buerke, M; Hoffmeister, HM	1
Byron, M; Gavozdea-Barna, M; Gulseth, MP; Hellwig, T; Zochert, S	1
Conard, J; Horellou, MH; Samama, MM	1
Matziolis, D; Matziolis, G; Perka, C	1
Clemens, A; Dahl, OE; Eriksson, BI; Kurth, AA; Noack, H; Rosencher, N	1
Dieterichs, C; Gaudu, T; Geck, M; Stokes, J; Truumees, E	1
Avezum, A; Connolly, SJ; Douketis, J; Eikelboom, J; Ezekowitz, M; Healey, JS; Heidbuchel, H; Heidbuchle, H; Oldgren, J; Reilly, P; Themeles, E; Wallentin, L; Yang, S; Yusuf, S	1
Haas, S; Kreutz, R; Llau, J; Norrving, B; Turpie, AG	1
Martin, EN; Money, SR; Shamoun, FE	1

Reviews

9 review(s) available for dabigatran and Blood Loss, Surgical

Article	Year
Management of Elective Surgery and Emergent Bleeding with Direct Oral Anticoagulants. Current cardiology reports, 2017, 10-24, Volume: 19, Issue:12 Topics: Administration, Oral; Antibodies, Monoclonal, Humanized; Anticoagulants; Antidotes; Antithrombins; Benzamides; Blood Loss, Surgical; Dabigatran; Deprescriptions; Elective Surgical Procedures; Factor Xa; Factor Xa Inhibitors; Hemorrhage; Humans; Practice Guidelines as Topic; Pyrazoles; Pyridines; Pyridones; Recombinant Proteins; Rivaroxaban; Thiazoles	2017
[Recommendations on use of direct oral anticoagulants in the perioperative period]. Medicina clinica, 2012, Volume: 139 Suppl 2 Topics: Administration, Oral; Anticoagulants; Benzimidazoles; beta-Alanine; Blood Loss, Surgical; Dabigatran; Humans; Morpholines; Perioperative Care; Postoperative Hemorrhage; Practice Guidelines as Topic; Pyrazoles; Pyridones; Rivaroxaban; Thiophenes; Venous Thromboembolism; Withholding Treatment	2012
Perioperative management of anticoagulation in elective surgery. ANZ journal of surgery, 2013, Volume: 83, Issue:11 Topics: Anticoagulants; Antithrombins; Benzimidazoles; beta-Alanine; Blood Loss, Surgical; Cardiovascular Diseases; Clopidogrel; Dabigatran; Elective Surgical Procedures; Humans; Perioperative Care; Platelet Aggregation Inhibitors; Postoperative Complications; Risk Assessment; Thromboembolism; Ticlopidine; Withholding Treatment	2013
Enhanced elimination of dabigatran through extracorporeal methods. Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2015, Volume: 11, Issue:1 Topics: Antithrombins; Biological Availability; Blood Loss, Surgical; Contraindications; Dabigatran; Drug Overdose; Emergency Medical Services; Evidence-Based Medicine; Hemodiafiltration; Hemorrhage; Humans; Renal Elimination; Tissue Distribution; Up-Regulation	2015
Spotlight on idarucizumab and its potential for the reversal of anticoagulant effects of dabigatran. Drug design, development and therapy, 2016, Volume: 10 Topics: Administration, Intravenous; Administration, Oral; Animals; Antibodies, Monoclonal, Humanized; Antidotes; Antithrombins; Blood Coagulation; Blood Coagulation Tests; Blood Loss, Surgical; Dabigatran; Drug Monitoring; Hemorrhage; Humans; Postoperative Hemorrhage; Risk Factors; Treatment Outcome	2016
[Management of NOAK administration during invasive or surgical interventions : When and how to pause and when to restart?] Medizinische Klinik, Intensivmedizin und Notfallmedizin, 2017, Volume: 112, Issue:2 Topics: Administration, Oral; Antibodies, Monoclonal, Humanized; Anticoagulants; Blood Loss, Surgical; Dabigatran; Drug Interactions; Half-Life; Humans; Pyrazoles; Pyridines; Pyridones; Rivaroxaban; Surgical Procedures, Operative; Thiazoles; Thromboembolism; Vitamin K	2017
Thromboprophylaxis in patients older than 75 years or with moderate renal impairment undergoing knee or hip replacement surgery [corrected]. International orthopaedics, 2012, Volume: 36, Issue:4 Topics: Aged; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Benzimidazoles; beta-Alanine; Blood Loss, Surgical; Dabigatran; Double-Blind Method; Enoxaparin; Fibrinolytic Agents; Humans; Prospective Studies; Randomized Controlled Trials as Topic; Renal Insufficiency; Venous Thromboembolism	2012
Management consensus guidance for the use of rivaroxaban--an oral, direct factor Xa inhibitor. Thrombosis and haemostasis, 2012, Volume: 108, Issue:5 Topics: Anticoagulants; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Atrial Fibrillation; Benzimidazoles; beta-Alanine; Blood Loss, Surgical; Clinical Trials as Topic; Dabigatran; Factor Xa Inhibitors; Female; Humans; Male; Morpholines; Practice Guidelines as Topic; Pregnancy; Rivaroxaban; Stroke; Thiophenes; Venous Thromboembolism; Venous Thrombosis; Warfarin	2012
The novel anticoagulants: the surgeons' prospective. Surgery, 2013, Volume: 153, Issue:3 Topics: Anticoagulants; Atrial Fibrillation; Benzimidazoles; beta-Alanine; Blood Loss, Surgical; Clinical Trials as Topic; Dabigatran; Humans; Morpholines; Pyrazoles; Pyridines; Pyridones; Rivaroxaban; Stroke; Surgical Procedures, Operative; Thiazoles; Thiophenes; Venous Thromboembolism; Warfarin	2013

Trials

3 trial(s) available for dabigatran and Blood Loss, Surgical

Article	Year
Design and rationale for RE-VERSE AD: A phase 3 study of idarucizumab, a specific reversal agent for dabigatran. Thrombosis and haemostasis, 2015, Volume: 114, Issue:1 Topics: Antibodies, Monoclonal, Humanized; Antithrombins; Blood Coagulation; Blood Coagulation Tests; Blood Loss, Surgical; Clinical Protocols; Coagulants; Dabigatran; Hemorrhage; Humans; Research Design; Treatment Outcome	2015
[The first antidote is available]. MMW Fortschritte der Medizin, 2016, Jun-09, Volume: 158, Issue:11 Topics: Antibodies, Monoclonal, Humanized; Blood Loss, Surgical; Dabigatran; Humans; Infusions, Intravenous	2016
Periprocedural bleeding and thromboembolic events with dabigatran compared with warfarin: results from the Randomized Evaluation of Long-Term Anticoagulation Therapy (RE-LY) randomized trial. Circulation, 2012, Jul-17, Volume: 126, Issue:3 Topics: Aged; Aged, 80 and over; Anticoagulants; Benzimidazoles; beta-Alanine; Blood Loss, Surgical; Brain Ischemia; Cardiac Pacing, Artificial; Cataract Extraction; Dabigatran; Female; Follow-Up Studies; Hemorrhage; Humans; Incidence; Male; Middle Aged; Postoperative Complications; Risk Factors; Stroke; Thromboembolism; Warfarin	2012

Other Studies

24 other study(ies) available for dabigatran and Blood Loss, Surgical

Article	Year
Dabigatran Reversal With Idarucizumab in Patients Requiring Urgent Surgery: A Subanalysis of the RE-VERSE AD Study. Annals of surgery, 2021, 09-01, Volume: 274, Issue:3 Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antithrombins; Blood Coagulation; Blood Loss, Surgical; Dabigatran; Emergencies; Female; Hemorrhage; Humans; Male; Middle Aged; Prospective Studies; Surgical Procedures, Operative	2021
Safety of cataract surgery in patients treated with the new oral anticoagulants (NOACs). Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2019, Volume: 257, Issue:12 Topics: Administration, Oral; Aged; Aged, 80 and over; Antithrombins; Blood Loss, Surgical; Dabigatran; Eye Hemorrhage; Factor Xa Inhibitors; Female; Follow-Up Studies; Humans; Incidence; Israel; Male; Middle Aged; Phacoemulsification; Postoperative Hemorrhage; Prospective Studies; Pyrazoles; Pyridones; Rivaroxaban; Thromboembolism	2019
A Survey of Direct Oral Anticoagulant Cessation in General Surgery and Outcomes in Patients with Nonvalvular Atrial Fibrillation. International heart journal, 2020, Sep-29, Volume: 61, Issue:5 Topics: Aged; Aged, 80 and over; Antithrombins; Atrial Fibrillation; Blood Loss, Surgical; Carotid Artery Diseases; Cerebral Infarction; Dabigatran; Digestive System Surgical Procedures; Elective Surgical Procedures; Embolism; Endoscopy; Factor Xa Inhibitors; Female; Humans; Male; Myocardial Infarction; Orthopedic Procedures; Perioperative Care; Postoperative Complications; Postoperative Hemorrhage; Pyrazoles; Pyridines; Pyridones; Retrospective Studies; Rivaroxaban; Thiazoles; Thromboembolism; Urologic Surgical Procedures; Vascular Surgical Procedures	2020
Predictors of Bleeding in the Perioperative Anticoagulant Use for Surgery Evaluation Study. Journal of the American Heart Association, 2020, 10-20, Volume: 9, Issue:19 Topics: Aged; Atrial Fibrillation; Blood Loss, Surgical; Dabigatran; Elective Surgical Procedures; Factor Xa Inhibitors; Female; Hemorrhage; Humans; Male; Medication Therapy Management; Perioperative Care; Pyrazoles; Pyridones; Risk Adjustment; Rivaroxaban; Stroke	2020
Real-World Experience with Idarucizumab to Reverse Anticoagulant Effect in Dabigatran-Treated Patients: Report of 11 Cases from Taiwan. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2018, Volume: 27, Issue:2 Topics: Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antithrombins; Blood Coagulation; Blood Loss, Surgical; Dabigatran; Evidence-Based Medicine; Female; Hemorrhage; Humans; Male; Risk Factors; Severity of Illness Index; Taiwan	2018
Target Population of Non-deferrable Surgery and Uncontrolled Severe Bleeding Related to Dabigatran. Cardiovascular drugs and therapy, 2018, Volume: 32, Issue:3 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antidotes; Antithrombins; Blood Coagulation; Blood Loss, Surgical; Clinical Decision-Making; Cost-Benefit Analysis; Dabigatran; Databases, Factual; Drug Costs; Female; Hospital Costs; Humans; Italy; Male; Middle Aged; Patient Selection; Postoperative Hemorrhage; Retrospective Studies; Young Adult	2018
Evaluation of the Bleeding Intensity of Patients Anticoagulated with Warfarin or Dabigatran Undergoing Dental Procedures. Arquivos brasileiros de cardiologia, 2018, Volume: 111, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Bleeding Time; Blood Loss, Surgical; Dabigatran; Female; Humans; Male; Middle Aged; Prospective Studies; Reference Values; Risk Factors; Statistics, Nonparametric; Time Factors; Tooth Extraction; Treatment Outcome; Warfarin	2018
Orthotopic liver transplantation in a patient receiving apixaban for portal vein thrombosis. Journal of clinical anesthesia, 2019, Volume: 56 Topics: Aged; Blood Loss, Surgical; Carcinoma, Hepatocellular; Dabigatran; Humans; Infusions, Intravenous; Liver Cirrhosis; Liver Neoplasms; Liver Transplantation; Male; Mesenteric Vascular Occlusion; Mesenteric Veins; Pyrazoles; Pyridones; Risk Assessment; Thromboembolism; Tranexamic Acid; Venous Thrombosis	2019
Pharmacologic interventions for reversing the effects of oral anticoagulants. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2013, May-15, Volume: 70, Issue:10 Suppl 1 Topics: Administration, Oral; Anticoagulants; Antifibrinolytic Agents; Antithrombins; Benzimidazoles; beta-Alanine; Blood Coagulation Factors; Blood Loss, Surgical; Dabigatran; Drug Therapy, Combination; Emergencies; Hemorrhage; Humans; International Normalized Ratio; Morpholines; Plasma; Pyrazoles; Pyridones; Rivaroxaban; Surgical Procedures, Operative; Thiophenes; Thromboembolism; Treatment Outcome; Vitamin K 1; Warfarin	2013
[Rivaroxaban, dabigatran and apixaban: new anticoagulants in operative urology]. Der Urologe. Ausg. A, 2014, Volume: 53, Issue:6 Topics: Administration, Oral; Anticoagulants; Benzimidazoles; beta-Alanine; Blood Loss, Surgical; Dabigatran; Humans; Morpholines; Postoperative Hemorrhage; Premedication; Pyrazoles; Pyridones; Rivaroxaban; Thiophenes; Treatment Outcome; Urologic Surgical Procedures	2014
New oral anticoagulants: a practical guide on prescription, laboratory testing and peri-procedural/bleeding management. Australasian Society of Thrombosis and Haemostasis. Internal medicine journal, 2014, Volume: 44, Issue:6 Topics: Administration, Oral; Anticoagulants; Atrial Fibrillation; Benzimidazoles; beta-Alanine; Blood Coagulation Tests; Blood Loss, Surgical; Contraindications; Dabigatran; Drug Interactions; Drug Monitoring; Drug Substitution; Elective Surgical Procedures; Emergencies; Hematoma, Epidural, Spinal; Hemorrhage; Humans; Kidney Diseases; Liver Diseases; Morpholines; Patient Selection; Pyrazoles; Pyridones; Rivaroxaban; Stroke; Thiophenes; Thrombophilia	2014
Perioperative bridging anticoagulation during dabigatran or warfarin interruption among patients who had an elective surgery or procedure. Substudy of the RE-LY trial. Thrombosis and haemostasis, 2015, Volume: 113, Issue:3 Topics: Adult; Aged; Anticoagulants; Atrial Fibrillation; Blood Loss, Surgical; Dabigatran; Drug Administration Schedule; Elective Surgical Procedures; Female; Humans; Logistic Models; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Perioperative Care; Postoperative Hemorrhage; Propensity Score; Proportional Hazards Models; Randomized Controlled Trials as Topic; Retrospective Studies; Risk Assessment; Risk Factors; Stroke; Surgical Procedures, Operative; Time Factors; Treatment Outcome; Warfarin	2015
Estimation of dabigatran plasma concentrations in the perioperative setting. An ex vivo study using dedicated coagulation assays. Thrombosis and haemostasis, 2015, Volume: 113, Issue:4 Topics: Antithrombins; Blood Coagulation Tests; Blood Loss, Surgical; Case-Control Studies; Chromatography, Liquid; Dabigatran; Drug Administration Schedule; Drug Monitoring; Humans; Limit of Detection; Linear Models; Partial Thromboplastin Time; Perioperative Care; Postoperative Hemorrhage; Predictive Value of Tests; Reproducibility of Results; Risk Factors; Tandem Mass Spectrometry; Thrombin Time; Time Factors	2015
[Fatal outcome for a patient in treatment with dabigatran suffering a subtrochanteric femoral fracture]. Ugeskrift for laeger, 2015, Apr-06, Volume: 177, Issue:15 Topics: Aged, 80 and over; Antithrombins; Atrial Fibrillation; Blood Loss, Surgical; Dabigatran; Fatal Outcome; Female; Hip Fractures; Humans; Radiography; Time-to-Treatment	2015
ISTH 2015 Congress. The Lancet. Haematology, 2015, Volume: 2, Issue:8 Topics: Antibodies, Monoclonal, Humanized; Anticoagulants; Arthroscopy; Blood Loss, Surgical; Dabigatran; Factor VIII; Hemophilia A; Humans; Randomized Controlled Trials as Topic; Rivaroxaban; Single-Domain Antibodies; Venous Thromboembolism	2015
Direct oral anticoagulant drugs (DOAC). Journal of cataract and refractive surgery, 2016, Volume: 42, Issue:1 Topics: Administration, Oral; Anticoagulants; Antithrombins; Blood Loss, Surgical; Cataract Extraction; Dabigatran; Eye Hemorrhage; Factor Xa Inhibitors; Humans; Pyrazoles; Pyridones; Rivaroxaban; Warfarin	2016
Cardiology Patient Pages: Antidotes for Bleeding Caused by Novel Oral Anticoagulants. Circulation, 2016, Jan-12, Volume: 133, Issue:2 Topics: Administration, Oral; Antibodies, Monoclonal, Humanized; Antithrombins; Blood Loss, Surgical; Cerebral Hemorrhage; Clinical Trials as Topic; Dabigatran; Drug Approval; Emergencies; Factor Xa; Factor Xa Inhibitors; Hemorrhage; Humans; Pyrazoles; Pyridines; Pyridones; Recombinant Proteins; Rivaroxaban; Thiazoles; United States; United States Food and Drug Administration	2016
[The use of new oral anticoagulants in surgery]. Khirurgiia, 2016, Issue:3 Topics: Anticoagulants; Blood Coagulation; Blood Loss, Surgical; Comorbidity; Dabigatran; Drug Interactions; Drug Overdose; Drug Substitution; Humans; Perioperative Period; Postoperative Hemorrhage; Risk Adjustment; Surgical Procedures, Operative	2016
Idarucizumab for Reversal of Dabigatran Prior to Acute Surgery: A Schematic Approach Based on a Case Report. Basic & clinical pharmacology & toxicology, 2017, Volume: 120, Issue:4 Topics: Aged; Antibodies, Monoclonal, Humanized; Antithrombins; Atrial Fibrillation; Blood Coagulation; Blood Coagulation Tests; Blood Loss, Surgical; Dabigatran; Humans; Intestinal Obstruction; Male; Postoperative Hemorrhage	2017
Reversal of direct oral anticoagulants for liver transplantation in cirrhosis: A step forward. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2017, Volume: 23, Issue:3 Topics: Administration, Intravenous; Administration, Oral; Antibodies, Monoclonal, Humanized; Anticoagulants; Blood Loss, Surgical; Dabigatran; End Stage Liver Disease; Humans; Liver Cirrhosis; Liver Transplantation; Male; Middle Aged; Preoperative Care; Severity of Illness Index; Treatment Outcome; Venous Thrombosis	2017
Successful use of laboratory monitoring to facilitate an invasive procedure for a patient treated with dabigatran. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2017, Apr-01, Volume: 74, Issue:7 Topics: Aged, 80 and over; Antithrombins; Atrial Fibrillation; Biomarkers; Blood Coagulation Tests; Blood Loss, Surgical; Dabigatran; Female; Femoral Neck Fractures; Hemiarthroplasty; Humans; Time Factors; Time-to-Treatment; Withholding Treatment	2017
[Pregnancy and venous thromboembolism. North-American and European guidelines. American College of Chest Physicians]. Journal des maladies vasculaires, 2009, Volume: 34, Issue:5 Topics: Abnormalities, Drug-Induced; Adult; Anticoagulants; Benzimidazoles; Blood Loss, Surgical; Cesarean Section; Contraindications; Dabigatran; Europe; Evidence-Based Medicine; Female; Fetus; Fondaparinux; Heparin; Heparin, Low-Molecular-Weight; Humans; Infant, Newborn; Morpholines; Polysaccharides; Practice Guidelines as Topic; Pregnancy; Pregnancy Complications, Hematologic; Puerperal Disorders; Pyridines; Rivaroxaban; Societies, Medical; Thiophenes; Thrombophilia; United States; Uterine Hemorrhage; Venous Thromboembolism; Warfarin	2009
Thromboembolism prophylaxis with dabigatran leads to lower perioperative blood loss than with dalteparin in primary knee arthroplasty. Archives of orthopaedic and trauma surgery, 2011, Volume: 131, Issue:12 Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Antithrombin Proteins; Arthroplasty, Replacement, Knee; Benzimidazoles; Blood Loss, Surgical; Case-Control Studies; Dabigatran; Dalteparin; Female; Humans; Male; Middle Aged; Pyridines; Retrospective Studies; Thromboembolism	2011
Epidural hematoma and intraoperative hemorrhage in a spine trauma patient on Pradaxa (dabigatran). Spine, 2012, Jun-15, Volume: 37, Issue:14 Topics: Aged; Anticoagulants; Benzimidazoles; Blood Loss, Surgical; Blood Transfusion; Dabigatran; Decompression, Surgical; Hematoma, Epidural, Cranial; Humans; Intraoperative Period; Male; Pyridines; Retrospective Studies; Spinal Fractures; Spinal Fusion; Thoracic Vertebrae; Treatment Outcome	2012