Page last updated: 2024-08-25

d-aspartic acid and Aging

d-aspartic acid has been researched along with Aging in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's13 (59.09)29.6817
2010's7 (31.82)24.3611
2020's2 (9.09)2.80

Authors

AuthorsStudies
Canu, N; Caputo, V; Cuomo, M; Errico, F; Usiello, A1
Becker, J; Eickhoff, SB; Mahlke, NS; Reckert, A; Ritz-Timme, S1
Fujii, N; Takata, T1
Affinito, O; Belardo, C; Chiariotti, L; Cristino, L; De Novellis, V; Errico, F; Florio, E; Imperatore, R; Keller, S; Luongo, L; Maddaloni, G; Maione, S; Migliarini, S; Nuzzo, T; Pasqualetti, M; Pollegioni, L; Punzo, D; Sacchi, S; Sisalli, MJ; Usiello, A1
Fujii, N; Kaji, Y1
Kafitz, KW; Kelly, T; Roderigo, C; Rose, CR1
Astone, D; D'Aniello, A; Errico, F; Giustizieri, M; Mazzola, C; Mercuri, NB; Napolitano, F; Nisticò, R; Pisapia, T; Usiello, A1
Capo, TR; Carlson, SL; Fieber, LA; Schmale, MC1
Fujii, N; Kaji, Y; Kinouchi, T; Mori, Y; Motoie, R; Nakamura, T1
Fujii, N; Fukayama, M; Kaji, Y; Oshika, T; Takazawa, Y1
Fujii, N; Kinouchi, T1
Kitamura, C; Masuda, W; Noguchi, T; Nouso, C; Terashita, M2
Fujii, N; Fujimoto, N; Kawada, A; Komatsu, T; Miura, Y; Saito, T; Tajima, S1
Fujii, N; Homma, H; Kinouchi, T1
Fujii, N; Hamamoto, T; Kagawa, Y; Kinouchi, T; Nishio, H; Nishiuchi, Y; Takada, K; Tsunemi, M1
Kraus, VB; McCudden, CR1
Abe, I; Kinoshita, Y; Ohtani, S; Yamamoto, T1
Fisher, G; Gaviria, R; Goff, T; Lopez, S; Lorenzo, N; Peterson, K; Philip, I; Tsesarskaia, M1
Fujii, N; Fukayama, M; Kaji, Y; Oshika, T; Takata, T; Takazawa, Y1
Blackshaw, S; Huang, AS; Lee, DA1
Fujii, N; Fujimoto, N; Shimo-Oka, T; Tajima, S; Takata, T; Tanaka, N1

Reviews

6 review(s) available for d-aspartic acid and Aging

ArticleYear
New insights on the influence of free d-aspartate metabolism in the mammalian brain during prenatal and postnatal life.
    Biochimica et biophysica acta. Proteins and proteomics, 2020, Volume: 1868, Issue:10

    Topics: Age Factors; Aging; Animals; Biomarkers; Brain; D-Aspartate Oxidase; D-Aspartic Acid; Dietary Supplements; Disease Susceptibility; Female; Gene Expression Regulation, Developmental; Gene Expression Regulation, Enzymologic; Mammals; Memory; Neurogenesis; Neuroprotection; Pregnancy; Receptors, N-Methyl-D-Aspartate

2020
Quantitative analysis of isomeric (l-α-, l-β-, D-α-, D-β-) aspartyl residues in proteins from elderly donors.
    Journal of pharmaceutical and biomedical analysis, 2015, Dec-10, Volume: 116

    Topics: Aged; Aging; Animals; Aspartic Acid Proteases; D-Aspartic Acid; Humans; Isoaspartic Acid; Isomerism; Peptide Fragments; Tandem Mass Spectrometry

2015
[Racemization of aspartyl residues of proteins in age-related disease].
    Seikagaku. The Journal of Japanese Biochemical Society, 2008, Volume: 80, Issue:4

    Topics: Aging; Alzheimer Disease; Arteriosclerosis; Cataract; D-Aspartic Acid; Humans; Molecular Structure; Proteins; Scleroderma, Localized; Stereoisomerism

2008
Collapse of homochirality of amino acids in proteins from various tissues during aging.
    Chemistry & biodiversity, 2010, Volume: 7, Issue:6

    Topics: Aging; Amino Acids; D-Aspartic Acid; Humans; Lens, Crystalline; Oxidative Stress; Proteins; Stereoisomerism; Ultraviolet Rays

2010
[D-amino acid biosystem in mammals].
    Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 2005, Volume: 50, Issue:5

    Topics: Aging; alpha-Crystallins; Alzheimer Disease; Amyloid beta-Peptides; Animals; Aspartic Acid Endopeptidases; Brain; Cataract; D-Aspartic Acid; Lens, Crystalline; Oxidative Stress; Prion Diseases; Protein D-Aspartate-L-Isoaspartate Methyltransferase; Skin; Stereoisomerism

2005
Biochemistry of amino acid racemization and clinical application to musculoskeletal disease.
    Clinical biochemistry, 2006, Volume: 39, Issue:12

    Topics: Aging; Amino Acids; Biomarkers; Collagen Type I; D-Aspartic Acid; Female; Forensic Sciences; Humans; Male; Middle Aged; Musculoskeletal Diseases; Stereoisomerism

2006

Other Studies

16 other study(ies) available for d-aspartic acid and Aging

ArticleYear
Age estimation based on different molecular clocks in several tissues and a multivariate approach: an explorative study.
    International journal of legal medicine, 2020, Volume: 134, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Arginine; Child; Child, Preschool; Chromatography, High Pressure Liquid; Collagen; D-Aspartic Acid; Epiglottis; Female; Forensic Medicine; Humans; Infant; Intervertebral Disc; Lysine; Male; Middle Aged; Models, Statistical; Multivariate Analysis; Young Adult

2020
Age-Related Changes in D-Aspartate Oxidase Promoter Methylation Control Extracellular D-Aspartate Levels and Prevent Precocious Cell Death during Brain Aging.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2016, Mar-09, Volume: 36, Issue:10

    Topics: Age Factors; Aging; Animals; Animals, Newborn; Azacitidine; Brain; Cell Death; D-Aspartate Oxidase; D-Aspartic Acid; Decitabine; Embryo, Mammalian; Enzyme Inhibitors; Male; Methylation; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurons; Promoter Regions, Genetic; Receptors, N-Methyl-D-Aspartate; RNA, Messenger

2016
Ammonium-evoked alterations in intracellular sodium and pH reduce glial glutamate transport activity.
    Glia, 2009, Volume: 57, Issue:9

    Topics: Aging; Animals; Aspartic Acid; Astrocytes; Biological Transport; Bumetanide; Cells, Cultured; Central Nervous System Agents; D-Aspartic Acid; Glutamic Acid; Hippocampus; Hydrogen-Ion Concentration; Immunohistochemistry; Quaternary Ammonium Compounds; Rats; Rats, Wistar; Sodium; Sodium Potassium Chloride Symporter Inhibitors; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 2

2009
Increased D-aspartate brain content rescues hippocampal age-related synaptic plasticity deterioration of mice.
    Neurobiology of aging, 2011, Volume: 32, Issue:12

    Topics: Aging; Animals; Brain; D-Aspartic Acid; Excitatory Postsynaptic Potentials; Exploratory Behavior; Hippocampus; Male; Maze Learning; Mice; Mice, Inbred C57BL; Neuronal Plasticity; Synapses; Up-Regulation

2011
Changes in D-aspartate ion currents in the Aplysia nervous system with aging.
    Brain research, 2010, Jul-09, Volume: 1343

    Topics: Aging; Animals; Aplysia; Cells, Cultured; Cellular Senescence; D-Aspartic Acid; Ganglia, Invertebrate; Glutamic Acid; Ion Channels; Models, Animal; Movement Disorders; Nervous System Physiological Phenomena; Neurons; Receptors, N-Methyl-D-Aspartate

2010
Accumulation of D-beta-aspartic acid-containing proteins in age-related ocular diseases.
    Chemistry & biodiversity, 2010, Volume: 7, Issue:6

    Topics: Aged; Aged, 80 and over; Aging; Antibodies; Bruch Membrane; Corneal Diseases; Corneal Stroma; D-Aspartic Acid; Eye Diseases; Female; Humans; Immunohistochemistry; Macular Degeneration; Male; Middle Aged; Pigment Epithelium of Eye; Proteins

2010
Substrate stereoselectivity of mammalian D-aspartyl endopeptidase.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2011, Nov-01, Volume: 879, Issue:29

    Topics: Adenosine Triphosphate; Aging; Animals; Aspartic Acid Endopeptidases; Chromatography, High Pressure Liquid; Crystallins; D-Aspartic Acid; Humans; Liver; Mice; Mitochondrial Membranes; NAD; Peptides; Stereoisomerism; Substrate Specificity

2011
D-Aspartic acid in bovine dentine non-collagenous phosphoprotein.
    Archives of oral biology, 2002, Volume: 47, Issue:11

    Topics: Aging; Amino Acids; Animals; Cattle; Chromatography, DEAE-Cellulose; D-Aspartic Acid; Dental Enamel Proteins; Dentin; Electrophoresis, Polyacrylamide Gel; Incisor; Phosphoproteins; Stereoisomerism

2002
Free D-aspartic acid in rat salivary glands.
    Archives of biochemistry and biophysics, 2003, Dec-01, Volume: 420, Issue:1

    Topics: Aging; Animals; D-Aspartic Acid; Female; Male; Organ Specificity; Parotid Gland; Rats; Rats, Wistar; Salivary Glands; Submandibular Gland; Tissue Distribution

2003
Immunohistochemical study of chronological and photo-induced aging skins using the antibody raised against D-aspartyl residue-containing peptide.
    Journal of cutaneous pathology, 2004, Volume: 31, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Biomarkers; Child; D-Aspartic Acid; Facial Dermatoses; Female; Humans; Immunohistochemistry; Male; Middle Aged; Photosensitivity Disorders; Skin; Ultraviolet Rays

2004
Isolation and characterization of mammalian D-aspartyl endopeptidase.
    Amino acids, 2007, Volume: 32, Issue:1

    Topics: Acetylcysteine; Aging; Alzheimer Disease; Animals; Aspartic Acid Endopeptidases; Caenorhabditis elegans; D-Aspartic Acid; Escherichia coli; Glutamate Dehydrogenase; Mice; Mitochondrial Membranes; Mitochondrial Proteins; Multienzyme Complexes; Oligopeptides; Protease Inhibitors; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Rabbits; Saccharomyces cerevisiae; Succinate Dehydrogenase

2007
Age-dependent changes in the racemisation ratio of aspartic acid in human alveolar bone.
    Archives of oral biology, 2007, Volume: 52, Issue:3

    Topics: Adolescent; Adult; Aged; Aging; Aspartic Acid; Child; D-Aspartic Acid; Female; Femur; Humans; Male; Mandible; Middle Aged; Sex Factors; Stereoisomerism

2007
Is there a correlation between age and D-aspartic acid in human knee cartilage?
    Amino acids, 2007, Volume: 32, Issue:1

    Topics: Aging; Brain; Cartilage; D-Aspartic Acid; Dentin; Eye; Female; Humans; Knee Joint; Male; Sex Characteristics

2007
Localization of D-beta-aspartic acid-containing proteins in human eyes.
    Investigative ophthalmology & visual science, 2007, Volume: 48, Issue:9

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; alpha-Crystallin A Chain; Blotting, Western; D-Aspartic Acid; Electrophoresis, Polyacrylamide Gel; Eye; Eye Proteins; Female; Humans; Immunoenzyme Techniques; Male; Middle Aged

2007
D-Aspartate and D-aspartate oxidase show selective and developmentally dynamic localization in mouse retina.
    Experimental eye research, 2008, Volume: 86, Issue:4

    Topics: Aging; Animals; D-Aspartate Oxidase; D-Aspartic Acid; Mice; Retina

2008
The presence of D-beta-aspartic acid-containing peptides in elastic fibers of sun-damaged skin: a potent marker for ultraviolet-induced skin aging.
    Biochemical and biophysical research communications, 2002, Jun-28, Volume: 294, Issue:5

    Topics: Aged; Aging; Aspartic Acid; Biomarkers; Child; D-Aspartic Acid; Elastic Tissue; Face; Humans; Immunohistochemistry; Isoaspartic Acid; Middle Aged; Peptides; Proteins; Skin; Ultraviolet Rays

2002