Page last updated: 2024-08-21

d-alpha tocopherol and Liver Neoplasms

d-alpha tocopherol has been researched along with Liver Neoplasms in 130 studies

Research

Studies (130)

TimeframeStudies, this research(%)All Research%
pre-199011 (8.46)18.7374
1990's27 (20.77)18.2507
2000's30 (23.08)29.6817
2010's44 (33.85)24.3611
2020's18 (13.85)2.80

Authors

AuthorsStudies
Asfiya, R; Bhattacharya, S; Kamra, M; Karande, AA; Maiti, B1
Gui, S; Guo, J; He, N; Huang, Y; Li, Z; Liang, X; Tang, M; Tao, Y1
Attia, Y; El-Nabarawi, M; Mahmoud, K; Swidan, S; Teaima, M1
Albanes, D; Hada, M; Mondul, AM; Weinstein, SJ1
De Zio, D; Di Leo, L; Filomeni, G; Mandatori, S; Rizza, S1
Capelletti, MM; Manceau, H; Peoc'h, K; Puy, H1
Hu, Y; Jiang, S; Li, M; Lv, H; Zhang, Z1
Abnet, CC; Albanes, D; Butt, J; Dawsey, SM; Freedman, ND; Koshiol, J; Lai, GY; McGlynn, KA; Michel, A; Murphy, G; Parisi, D; Pawlita, M; Snyder, K; Taylor, PR; Virtamo, J; Weinstein, SJ1
Albanes, D; Freedman, ND; Lai, GY; McGlynn, KA; Taylor, PR; Virtamo, J; Weinstein, SJ1
Albanes, D; Freedman, ND; Gail, MH; Lai, GY; McGlynn, KA; Taylor, PR; Virtamo, J; Weinstein, SJ1
Deng, S; Gao, M; Guan, X; Liu, H; Lv, L; Tian, Y; Xu, H; Zhang, C1
Guo, Z; Jiao, Y; Muhammad, N; Wang, K; Wang, X; Zhu, C; Zhu, Z1
Nishino, H2
Caro, AA; Cederbaum, AI1
Jun, HS; Kim, SE; Sung, MK1
Cai, D; Guo, J; Min, J; Zhao, F3
Itoshima, T; Kawaguchi, M; Okita, M; Osawa, T; Ota, Y; Sakai, N; Sasagawa, T; Tomioka, K1
Hashimoto, Y; Kabeya, K; Kakizaki, S; Kaneko, M; Konaka, K; Mori, M; Nagamine, T; Sato, K; Shimojo, H; Sohara, N; Tago, Y; Takagi, H; Takahashi, H; Takayama, H; Tsukioka, G; Yamada, T1
Bulla, GA; Kraus, DM; Schmitz, EK1
Hosotani, K; Inui, H; Kawahata, A; Koyama, K; Murakami, C; Nakano, Y; Yamaji, R; Yoshida, H1
Barella, L; Fischer, A; Rimbach, G; Stoecklin, E1
Chuang, CH; Hu, ML; Huang, CS; Shih, MK1
Cederbaum, AI; Chen, Q; Galleano, M1
Factor, VM; Jensen, MR; Laskowska, D; Popescu, NC; Thorgeirsson, SS; Woitach, JT1
Fujii, H; Hara, N; Itoh, Y; Nakajima, A; Okanoue, T; Seko, Y; Sumida, Y; Takahashi, H; Yoneda, M1
Alvarez, ML; Carrillo, MC; Ceballos, MP; Comanzo, CG; Ferretti, AC; Lorenzetti, F; Lucci, A; Quiroga, AD; Vera, MC1
Breder, VV; Doshchitsin, VL; Dudinskaya, EN; Ershova, EV; Geyvandova, NI; Ivashkin, VT; Kodzoeva, KB; Komshilova, KA; Korochanskaya, NV; Kotovskaya, YV; Maevskaya, MV; Mayorov, AY; Mishina, EE; Nadinskaya, MY; Nikitin, IG; Pogosova, NV; Shamkhalova, MS; Shestakova, MV; Tarzimanova, AI; Tkacheva, ON; Troshina, EA1
Chen, XP; Li, GW; Li, Y; Zhang, Y1
Li, X; Li, Z; Lian, D; Liu, J; Ye, L1
Chen, H; Li, W; Lu, Y; Tao, R; Wang, C; Zhang, C; Zhou, H1
Kurmi, BD; Paliwal, R; Paliwal, SR; Tekchandani, P1
Abagyan, R; Feng, J; He, X; Liu, Y; Shi, D; Xiang, T; Yan, S; Zhang, J; Zhang, Y; Zhong, C1
Li, D; Liu, S; Shen, L; Zhang, QY; Zhu, H; Zhu, J1
Abbondanzieri, AA; Alvarez, ML; Carrillo, MC; Ceballos, MP; Comanzo, CG; Ferretti, AC; Lorenzetti, F; Lucci, A; Pisani, GB; Quiroga, AD; Vera, MC1
Seen, S1
Du, Z; Fu, J; Hu, J; Mao, Y; Yin, J; You, Q; Zhang, P1
Huang, QF; Jiang, YY; Liu, M; Lu, XX; Shao, CL; Wang, GH; Zhang, JM1
Banini, BA; Sanyal, AJ1
Chan, HL; Chan, WK; Chawla, Y; Chitturi, S; Dan, YY; Duseja, A; Fan, J; Farrell, G; Goh, KL; Hamaguchi, M; Hashimoto, E; Kim, SU; Lesmana, LA; Lin, YC; Liu, CJ; Ni, YH; Sollano, J; Wong, GL; Wong, SK; Wong, VW1
Chen, B; Chen, D; Liu, Y; Omari-Siaw, E; Xu, W; Xu, X; Yu, J; Zhang, H1
Adinolfi, LE; Lonardo, A; Marrazzo, A; Maurantonio, M; Nascimbeni, F; Rinaldi, L1
Issa, D; Patel, V; Sanyal, AJ1
Li, Z; Qin, Y; Tu, K; Xu, C; Yang, C; Zhang, Z1
Dong, H; Gao, M; Li, Q; Pang, Y; Tian, Y; Wang, J; Wu, G; Xu, H; Zhang, B; Zhang, C; Zhang, H1
Chaiyakunapruk, N; Chongmelaxme, B; Dilokthornsakul, P; Phisalprapa, P; Sawangjit, R1
Chen, D; Gao, J; Lu, Y; Pan, X; Xie, F; Yin, C; Zhang, Y; Zou, H1
Li, A; Liang, Y; Lyu, Y; Tang, X; Xie, D; Zheng, D1
Burdeos, GC; Kimura, F; Miyazawa, T; Nakagawa, K; Watanabe, A1
Baccino, FM; Bonelli, G; Costelli, P; Khadjavi, A; Minero, VG1
Chu, M; Guo, Y; Liu, H; Otieno, BO; Tan, S; Xu, C; Yang, X; Zhang, Z; Zhao, S1
Ahn, KS; Fong, CW; Hui, KM; Kumar, AP; Li, F; Ong, TH; Sethi, G; Shanmugam, MK; Siveen, KS; Tergaonkar, V; Yap, WN1
Chen, X; Li, Y; Meng, Q; Sun, H; Xu, P; Yin, Q; Yu, H; Zhang, Z1
Bao, X; Chu, QC; Gao, M; Guan, X; Jiang, N; Liu, KX; Tian, Y; Xu, H; Zhang, CH1
Guo, Y; Si, L; Song, Q; Tan, S; Wu, T; Ye, Q; Zhang, Z; Zhao, Y; Zhuang, X1
Chen, M; Fang, X; Li, Y; Wang, Y; Zhang, J; Zhou, D1
Abdul Rahman Sazli, F; Abdul Rahman, M; Jubri, Z; Karsani, SA; Md Top, AG; Wan Ngah, WZ1
Halilbasic, E; Hofer, H; Kazemi-Shirazi, L; Kienbacher, C; Munda, P; Rechling, C; Trauner, M; Traussnigg, S1
Cai, S; Chen, K; Liang, Y; Liu, L; Liu, X; Shen, J; Sui, X; Tan, Y; Tang, X; Wu, B; Xie, C; Yang, L; Zhang, C; Zhang, F; Zhang, M; Zhang, R; Zheng, D1
Di-Wen, S; Hao, L; Pan, GZ; Wang, P; Xue, QZ; Yuan, QZ; Zhang, J1
Gao, L; Hao, D; Liu, G; Ma, J; Wang, X; Wei, P; Zhou, L1
Chu, Q; Deng, S; Gao, M; Guan, X; Huo, X; Liu, H; Liu, K; Ma, X; Tian, Y; Xu, H1
Deng, S; Gao, D; Gao, M; Gao, X; Liu, H; Lv, L; Ma, C; Tian, Y; Wang, C; Xu, H; Zhang, C1
Bao, X; Deng, S; Gao, D; Gao, M; Guan, X; Liu, H; Lv, L; Tian, Y; Wang, C; Xu, H; Zhang, C1
Burdeos, GC; Eitsuka, T; Ito, J; Kimura, F; Miyazawa, T; Nakagawa, K1
Cheng, SB; Huang, YC; Huang, YT; Lin, PT; Liu, HT2
Oseini, AM; Sanyal, AJ1
Hsiao, JK; Huang, JC; Lee, KT; Lin, SK; Ma, H; Tsai, LY; Tsai, SM; Wu, SH1
Albanes, D; Bertoia, M; Männistö, S; Mayne, ST; Virtamo, J; Wright, ME1
Chang, CP; Nesaretnam, K; Ong, S; Shiba, S; Teo, VH; Xu, CH; Yap, WN; Yap, YL; Zaiden, N; Zhang, XW1
Kumar, AP; Li, F; Loo, SY; Manu, KA; Rajendran, P; Sethi, G; Shanmugam, MK1
Abbott-Johnson, W; Clague, A; Cuneo, R; Johnson, H; Kerlin, P1
Grønbæk, H; Heebøll, S; Kazankov, K; Poulsen, MK; Vilstrup, H1
Lu, Y; Shan, W; Wang, T; Xiong, S; Yin, X1
Cai, H; Gao, J; Gao, YT; Ji, BT; Li, H; Shu, XO; Xiang, YB; Yang, G; Zhang, W; Zheng, W1
Barnett, KT; Fokum, FD; Malafa, MP1
Hirakawa, Y; Inui, H; Murakami, C; Nakano, Y; Yoshida, H1
Jordão Júnior, AA; Marchini, JS; Meirelles, MS; Portari, GV; Vannucchi, H1
Cetin-Atalay, R; Ince, G; Irmak, MB; Ozturk, M1
BAUMANN, CA; MILLER, WL; RUMSFELD, HW; SWICK, RW1
Huff, J1
Anderson, K; Atkinson, J; Kline, K; Lawson, KA; Sanders, BG; Simmons-Menchaca, M; Sun, L1
Calvisi, DF; Factor, VM; Hironaka, K; Ladu, S; Thorgeirsson, SS1
Bunaciu, RP; Glauert, HP; Kumar, A; Lee, EY; Lehmler, HJ; Lu, Z; Patel, S; Robertson, LW; Spear, BT; Stemm, DN; Tharappel, JC1
Gregor, JI; Guski, H; Heukamp, I; Jacobi, CA; Kilian, M; Neumann, A; Schimke, I; Walz, MK; Wenger, FA1
Lin, CC; Ng, LT; Wu, SJ1
Adamsky, K; Amariglio, N; Breda, L; Cabantchik, ZI; Rachmilewitz, EA; Rechavi, G; Rivella, S; Weizer-Stern, O1
Okabe, M; Sakai, M; Tachibana, H; Yamada, K1
Ando, T; Hagiwara, S; Kakizaki, S; Kori, T; Mori, M; Nagasaka, K; Ohno, Y; Otsuka, T; Takagi, H; Takahashi, T; Takeuchi, K; Tojima, H; Tomioka, S; Yoshida, H1
Kondo, M; Takemura, S; Yoshikawa, T1
Gorozhanskaia, EG; Patiutko, II; Sagaidak, IV1
Asamoto, M; Hirono, I; Iigo, M; Ito, M; Iwahori, Y; Matsumoto, K; Nagao, M; Tsuda, H; Uehara, N1
Bassi, A; Capra, F; Casaril, M; Corrocher, R; Corso, F; Gabrielli, GB; Nicoli, N; Stanzial, AM1
Burke, MD; Duthie, SJ; Melvin, WT1
Huang, SM; Liaw, YF; Lin, DI; Lin, WG; Pan, WH; Wang, CY; Yeh, SY1
Clark, RW; Gordon, DA; Parker, RA; Pearce, BC; Wright, JJ1
Brewster, MA; Turley, CP1
Azuma, H; Kanagawa, Y; Mima, N; Miyamoto, K; Saito, S; Shigekiyo, T; Shirakawa, M; Watanabe, A; Yamaguchi, H1
Chappey, B; Moatti, N; Myara, I; Pech-Amsellem, MA; Pico, I; Vedie, B1
Moriwaki, H; Muto, Y; Nakamura, N; Shidoji, Y1
Failla, ML; Loo, G; Martin, KR1
Chen, HW; Ko, JJ; Lii, CK1
Chamuleau, RA; Groenink, M; Hoek, FJ; Reitsma, PH; van Deventer, SJ; Wu, CG1
Borghi, A; Camellini, L; Casalgrandi, G; Cioni, G; D'Alimonte, P; Rocchi, E; Seium, Y1
Chen, CJ; Chiang, YC; Lien, JP; Yu, MW1
Yamamoto, Y; Yamashita, S2
Henning, SM; Ivandic, BT; Liao, F; Swendseid, ME1
Hirai, T; Iwata, T; Kuwahara, M; Toge, T; Yamashita, Y; Yoshimoto, A1
Fujisawa, A; Kokura, S; Yamamoto, Y; Yamashita, S; Yoshikawa, T1
Frøyen, P; Høstmark, AT; Jebens, E; Lystad, E; Skramstad, J1
Lim, SF; Tan, IK1
Kamendulis, LM; Klaunig, JE1
Cederbaum, AI; Marí, M1
Kang, JH; Shi, YM; Zheng, RL1
Hobara, N; Watanabe, A1
Suzuki, S1
Høstmark, AT; Lystad, E1
Bonkovsky, HL1
Hirose, M; Ito, N; Nakamura, A; Ogawa, K; Shirai, T; Takahashi, S1
Kanematsu, T; Kawano, T; Kuwano, M; Matsumata, T; Sugimachi, K; Takenaka, K1
Chen, YT; Ding, JH1
Ito, N; Masui, T; Moore, MA; Thamavit, W; Tsuda, H1
Dickie, MM; Hancock, RL1
Oldfield, JE1
Bagleĭ, EA; Sidorik, EP1
Exon, JH; Harr, JR; Weswig, PH; Whanger, PD1

Reviews

12 review(s) available for d-alpha tocopherol and Liver Neoplasms

ArticleYear
Ferroptosis in Liver Diseases: An Overview.
    International journal of molecular sciences, 2020, Jul-11, Volume: 21, Issue:14

    Topics: alpha-Tocopherol; Animals; Autophagy; Chemical and Drug Induced Liver Injury; Cyclohexylamines; Cysteine; Ferroptosis; Glutathione; Heme; Humans; Iron; Kelch-Like ECH-Associated Protein 1; Lipid Peroxidation; Lipoxygenase; Liver Diseases; Liver Neoplasms; Oxidative Stress; Phenylenediamines; Phospholipid Hydroperoxide Glutathione Peroxidase; Piperazines; Quinoxalines; Reactive Oxygen Species; Reperfusion Injury; Signal Transduction; Sorafenib; Spiro Compounds; Sulfasalazine; Tumor Suppressor Protein p53

2020
Chronic liver disease and oxidative stress - a narrative review.
    Expert review of gastroenterology & hepatology, 2021, Volume: 15, Issue:9

    Topics: Animals; Antioxidants; Antiviral Agents; Carcinoma, Hepatocellular; Chronic Disease; Dietary Supplements; Flavonoids; Hepatitis B, Chronic; Hepatitis C, Chronic; Humans; Liver Cirrhosis; Liver Diseases; Liver Diseases, Alcoholic; Liver Neoplasms; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Reactive Oxygen Species; Vitamin E

2021
Current and future pharmacologic treatment of nonalcoholic steatohepatitis.
    Current opinion in gastroenterology, 2017, Volume: 33, Issue:3

    Topics: Gastrointestinal Microbiome; Humans; Hypoglycemic Agents; Inflammation; Liver Cirrhosis; Liver Neoplasms; Molecular Targeted Therapy; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Pioglitazone; Thiazolidinediones; Vitamin E

2017
The Asia-Pacific Working Party on Non-alcoholic Fatty Liver Disease guidelines 2017-Part 2: Management and special groups.
    Journal of gastroenterology and hepatology, 2018, Volume: 33, Issue:1

    Topics: Adolescent; Asia; Bariatric Surgery; Carcinoma, Hepatocellular; Chenodeoxycholic Acid; Child; Diet; Exercise; Fatty Acids, Omega-3; Gastroenterology; Humans; Liver Neoplasms; Liver Transplantation; Non-alcoholic Fatty Liver Disease; Obesity; Pacific Islands; Practice Guidelines as Topic; Risk; Systematic Reviews as Topic; Thiazolidinediones; Vitamin E

2018
Nonalcoholic fatty liver disease: Evolving paradigms.
    World journal of gastroenterology, 2017, Sep-28, Volume: 23, Issue:36

    Topics: Biomarkers; Chenodeoxycholic Acid; Diabetes Mellitus, Type 2; Diagnostic Imaging; Diet, Reducing; Dyslipidemias; Exercise Therapy; Humans; Hyperuricemia; Hypoglycemic Agents; Liver; Liver Function Tests; Liver Neoplasms; Mass Screening; Metabolic Syndrome; Non-alcoholic Fatty Liver Disease; Prevalence; Risk Assessment; Risk Factors; Vitamin E

2017
Future therapy for non-alcoholic fatty liver disease.
    Liver international : official journal of the International Association for the Study of the Liver, 2018, Volume: 38 Suppl 1

    Topics: Animals; Diet; Gastrointestinal Microbiome; Humans; Hypoglycemic Agents; Inflammation; Life Style; Liver Cirrhosis; Liver Neoplasms; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Thiazolidinediones; Vitamin E

2018
Challenges and Management of Liver Cirrhosis: Practical Issues in the Therapy of Patients with Cirrhosis due to NAFLD and NASH.
    Digestive diseases (Basel, Switzerland), 2015, Volume: 33, Issue:4

    Topics: Anticholesteremic Agents; Antioxidants; Bariatric Surgery; Carcinoma, Hepatocellular; Disease Progression; Genetic Variation; Humans; Hypoglycemic Agents; Lipase; Liver; Liver Cirrhosis; Liver Neoplasms; Liver Transplantation; Membrane Proteins; Metabolic Syndrome; Metformin; Non-alcoholic Fatty Liver Disease; Obesity, Morbid; Prognosis; Receptors, Cytoplasmic and Nuclear; Vitamin E

2015
Therapies in non-alcoholic steatohepatitis (NASH).
    Liver international : official journal of the International Association for the Study of the Liver, 2017, Volume: 37 Suppl 1

    Topics: Carcinoma, Hepatocellular; Diet; Disease Progression; Exercise; Fibrosis; Humans; Hypoglycemic Agents; Liver; Liver Cirrhosis; Liver Neoplasms; Liver Transplantation; Non-alcoholic Fatty Liver Disease; Pioglitazone; Randomized Controlled Trials as Topic; Risk Factors; Thiazolidinediones; Vitamin E

2017
Role of iron in inducing oxidative stress in thalassemia: Can it be prevented by inhibition of absorption and by antioxidants?
    Annals of the New York Academy of Sciences, 2005, Volume: 1054

    Topics: Acetylcysteine; Animals; Antimicrobial Cationic Peptides; Antioxidants; Bone Marrow; Carcinoma, Hepatocellular; Cell Line, Tumor; Disease Models, Animal; Drug Therapy, Combination; Erythrocytes; Gene Expression Regulation; Genetic Therapy; Hepcidins; Humans; Intestinal Absorption; Iron; Iron Chelating Agents; Iron, Dietary; Liver Neoplasms; Mice; Oxidants; Oxidative Stress; Thalassemia; Vitamin E

2005
Iron and the liver.
    The American journal of the medical sciences, 1991, Volume: 301, Issue:1

    Topics: Ascorbic Acid; Carcinoma, Hepatocellular; Collagen; Free Radicals; Hemochromatosis; Humans; Iron; Liver; Liver Cirrhosis; Liver Neoplasms; Lysosomes; Membrane Potentials; Porphyrias; Potassium; Transferrin; Uroporphyrins; Vitamin E

1991
The selenium story: some reflections on the "moon-metal".
    New Zealand veterinary journal, 1974, Volume: 22, Issue:6

    Topics: Animals; Cattle; Cattle Diseases; Deficiency Diseases; Dental Caries; Diarrhea; Female; Humans; Infertility; Liver Diseases; Liver Neoplasms; Male; Neoplasms; Rats; Selenium; Sheep; Sheep Diseases; Swine; Swine Diseases; Vitamin E

1974
[Anti-oxidants and free radicals of lipids in the tumor process].
    Voprosy onkologii, 1970, Volume: 16, Issue:10

    Topics: Animals; Antioxidants; Chemistry, Organic; Free Radicals; In Vitro Techniques; Kinetics; Lipid Metabolism; Liver Neoplasms; Luminescent Measurements; Mitochondria; Neoplasms, Experimental; Organic Chemistry Phenomena; Oxidation-Reduction; Oxidative Phosphorylation; Oxidoreductases; Oxygen Consumption; Radiochemistry; Sarcoma 180; Sarcoma, Experimental; Sulfhydryl Compounds; Vitamin E

1970

Trials

6 trial(s) available for d-alpha tocopherol and Liver Neoplasms

ArticleYear
Serum Retinol and Risk of Overall and Site-Specific Cancer in the ATBC Study.
    American journal of epidemiology, 2020, 06-01, Volume: 189, Issue:6

    Topics: Aged; Alcohol Drinking; alpha-Tocopherol; beta Carotene; Body Weights and Measures; Cholesterol, HDL; Chromatography, High Pressure Liquid; Diet; Dietary Supplements; Double-Blind Method; Exercise; Finland; Humans; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Neoplasms; Proportional Hazards Models; Prostatic Neoplasms; Residence Characteristics; Smoking; Socioeconomic Factors

2020
Effects of α-tocopherol and β-carotene supplementation on liver cancer incidence and chronic liver disease mortality in the ATBC study.
    British journal of cancer, 2014, Dec-09, Volume: 111, Issue:12

    Topics: Aged; alpha-Tocopherol; beta Carotene; Chronic Disease; Humans; Incidence; Liver Diseases; Liver Neoplasms; Male; Middle Aged

2014
Phytochemicals in hepatocellular cancer prevention.
    Nutrition and cancer, 2009, Volume: 61, Issue:6

    Topics: alpha-Tocopherol; Animals; Anticarcinogenic Agents; beta Carotene; Carcinoma, Hepatocellular; Carotenoids; Cryptoxanthins; Dietary Supplements; Hepatitis, Viral, Human; Humans; Inositol; Kaplan-Meier Estimate; Liver Cirrhosis; Liver Neoplasms; Lycopene; Male; Mice; Mice, Inbred C3H; Tumor Burden; Xanthophylls

2009
Pilot clinical trial of the use of alpha-tocopherol for the prevention of hepatocellular carcinoma in patients with liver cirrhosis.
    International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 2003, Volume: 73, Issue:6

    Topics: Alanine Transaminase; alpha-Fetoproteins; alpha-Tocopherol; Antioxidants; Carcinoma, Hepatocellular; Cholesterol; Female; Hepatitis C, Chronic; Humans; Liver Cirrhosis; Liver Neoplasms; Male; Middle Aged; Pilot Projects; Platelet Count; Serum Albumin; Survival Rate

2003
Prevention of hepatocellular carcinoma in chronic viral hepatitis patients with cirrhosis by carotenoid mixture.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 2007, Volume: 174

    Topics: alpha-Tocopherol; Carcinoma, Hepatocellular; Carotenoids; Female; Hepatitis C; Hepatitis, Viral, Human; Humans; Liver Cirrhosis; Liver Neoplasms; Male; Middle Aged

2007
Effects of coenzyme Q10 supplementation on antioxidant capacity and inflammation in hepatocellular carcinoma patients after surgery: a randomized, placebo-controlled trial.
    Nutrition journal, 2016, 10-06, Volume: 15, Issue:1

    Topics: Aged; Antioxidants; Biomarkers; Body Mass Index; Body Weight; C-Reactive Protein; Carcinoma, Hepatocellular; Catalase; Dietary Supplements; Female; Humans; Inflammation; Interleukin-6; Linear Models; Liver Neoplasms; Male; Malondialdehyde; Middle Aged; Oxidative Stress; Single-Blind Method; Superoxide Dismutase; Ubiquinone; Vitamin E

2016

Other Studies

112 other study(ies) available for d-alpha tocopherol and Liver Neoplasms

ArticleYear
Novel α-tocopherol-ferrocene conjugates for the specific delivery of transgenes in liver cancer cells under high serum conditions.
    Biomaterials science, 2021, Nov-09, Volume: 9, Issue:22

    Topics: alpha-Tocopherol; Caco-2 Cells; Cations; Gene Transfer Techniques; Humans; Liposomes; Liver Neoplasms; Metallocenes; Transfection; Transgenes

2021
Sorafenib-Loaded PLGA-TPGS Nanosystems Enhance Hepatocellular Carcinoma Therapy Through Reversing P-Glycoprotein-Mediated Multidrug Resistance.
    AAPS PharmSciTech, 2022, Apr-29, Volume: 23, Issue:5

    Topics: alpha-Tocopherol; Animals; ATP Binding Cassette Transporter, Subfamily B; Carcinoma, Hepatocellular; Drug Resistance, Multiple; Glycolates; Humans; Lactic Acid; Liver Neoplasms; Mice; Mice, Nude; Polyesters; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Sorafenib; Vitamin E

2022
Size-optimized simvastatin-loaded TPGS modified lipid nanocapsules for targeting epithelial-to-mesenchymal transition in hepatocellular carcinoma: Role of PTEN/AKT signaling.
    Expert opinion on drug delivery, 2023, Volume: 20, Issue:5

    Topics: alpha-Tocopherol; Carcinoma, Hepatocellular; Cell Line, Tumor; Humans; Lipids; Liver Neoplasms; Nanocapsules; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Simvastatin; Tissue Distribution

2023
Mitophagy contributes to alpha-tocopheryl succinate toxicity in GSNOR-deficient hepatocellular carcinoma.
    Biochemical pharmacology, 2020, Volume: 176

    Topics: Aldehyde Oxidoreductases; alpha-Tocopherol; Antioxidants; Autophagosomes; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Hep G2 Cells; Humans; Liver Neoplasms; Microscopy, Confocal; Microscopy, Electron, Transmission; Mitochondria; Mitophagy; RNA Interference

2020
Multifunctional self-assembled micelles of galactosamine-hyaluronic acid-vitamin E succinate for targeting delivery of norcantharidin to hepatic carcinoma.
    Carbohydrate polymers, 2018, Oct-01, Volume: 197

    Topics: alpha-Tocopherol; Animals; Antineoplastic Agents; Bridged Bicyclo Compounds, Heterocyclic; Carcinoma, Hepatocellular; Cell Proliferation; Dose-Response Relationship, Drug; Drug Delivery Systems; Drug Screening Assays, Antitumor; Female; Galactosamine; Hep G2 Cells; Humans; Hyaluronic Acid; Liver Neoplasms; Liver Neoplasms, Experimental; MCF-7 Cells; Mice; Mice, Inbred BALB C; Mice, Nude; Micelles; Molecular Structure; Structure-Activity Relationship

2018
Association of seropositivity to Helicobacter species and biliary tract cancer in the ATBC study.
    Hepatology (Baltimore, Md.), 2014, Volume: 60, Issue:6

    Topics: alpha-Tocopherol; beta Carotene; Biliary Tract Neoplasms; Carcinoma, Hepatocellular; Case-Control Studies; Helicobacter Infections; Humans; Liver Neoplasms; Male; Middle Aged; Randomized Controlled Trials as Topic; Vitamins

2014
Association of serum α-tocopherol, β-carotene, and retinol with liver cancer incidence and chronic liver disease mortality.
    British journal of cancer, 2014, Nov-25, Volume: 111, Issue:11

    Topics: Aged; alpha-Tocopherol; beta Carotene; Chronic Disease; Humans; Incidence; Liver Diseases; Liver Neoplasms; Male; Middle Aged; Vitamin A

2014
A Promising Emodin-Loaded Poly (Lactic-Co-Glycolic Acid)-d-α-Tocopheryl Polyethylene Glycol 1000 Succinate Nanoparticles for Liver Cancer Therapy.
    Pharmaceutical research, 2016, Volume: 33, Issue:1

    Topics: alpha-Tocopherol; Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Delayed-Action Preparations; Drug Delivery Systems; Emodin; Humans; Lactic Acid; Liver Neoplasms; Mice; Nanoparticles; Particle Size; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats, Sprague-Dawley

2016
Dual-drug loaded nanoformulation with a galactosamine homing moiety for liver-targeted anticancer therapy.
    Dalton transactions (Cambridge, England : 2003), 2016, Aug-16, Volume: 45, Issue:33

    Topics: alpha-Tocopherol; Antineoplastic Agents; Caspase 3; Cell Line, Tumor; Cell Survival; Drug Carriers; Drug Liberation; Galactosamine; Humans; Lactic Acid; Liver Neoplasms; Nanoparticles; Platinum; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Prodrugs; Reactive Oxygen Species

2016
Ca2+-dependent and independent mitochondrial damage in HepG2 cells that overexpress CYP2E1.
    Archives of biochemistry and biophysics, 2002, Dec-15, Volume: 408, Issue:2

    Topics: alpha-Tocopherol; Arachidonic Acid; Calcium; Calpain; Carcinoma, Hepatocellular; Culture Media; Cyclosporine; Cysteine Proteinase Inhibitors; Cytochrome P-450 CYP2E1; Cytosol; Dipeptides; Humans; Intracellular Membranes; Iron; Lipid Peroxidation; Liver Neoplasms; Mitochondria, Liver; Oxidative Stress; Permeability; Tumor Cells, Cultured

2002
Protective effect of soybean saponins and major antioxidants against aflatoxin B1-induced mutagenicity and DNA-adduct formation.
    Journal of medicinal food, 2002,Winter, Volume: 5, Issue:4

    Topics: Aflatoxin B1; alpha-Tocopherol; Anticarcinogenic Agents; Antioxidants; Ascorbic Acid; Butylated Hydroxytoluene; Carcinoma, Hepatocellular; DNA Adducts; Dose-Response Relationship, Drug; Glycine max; Humans; Liver Neoplasms; Mutagenicity Tests; Mutagens; Mutation; Saponins; Treatment Outcome; Tumor Cells, Cultured

2002
[Effect of different vitamin E homologous analogues on human hepatoma cell HepG2 proliferation in vitro].
    Wei sheng yan jiu = Journal of hygiene research, 2003, Volume: 32, Issue:1

    Topics: alpha-Tocopherol; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Division; gamma-Tocopherol; Humans; Liver Neoplasms; Tocopherols; Tumor Cells, Cultured; Vitamin E

2003
[Effect of apoptosis induced by different vitamin E homologous analogues in human hepatoma cells (HepG2)].
    Wei sheng yan jiu = Journal of hygiene research, 2003, Volume: 32, Issue:2

    Topics: alpha-Tocopherol; Antineoplastic Agents; Antioxidants; Apoptosis; Carcinoma, Hepatocellular; gamma-Tocopherol; Humans; Liver Neoplasms; Tocopherols; Tumor Cells, Cultured; Vitamin E

2003
Arachidonic acid in mononuclear cells and its clinical significance in HCV cirrhotic patients.
    Nutrition (Burbank, Los Angeles County, Calif.), 2003, Volume: 19, Issue:9

    Topics: Aged; alpha-Tocopherol; Arachidonic Acid; Carcinoma, Hepatocellular; Case-Control Studies; Chromatography, Gas; Chromatography, High Pressure Liquid; Disease Progression; Enzyme-Linked Immunosorbent Assay; Fatty Acids; Female; Hepatitis C; Humans; Leukocytes, Mononuclear; Liver Cirrhosis; Liver Neoplasms; Lymphocyte Count; Male; Middle Aged; Phospholipids; Platelet Count; Thiobarbituric Acid Reactive Substances; Tumor Necrosis Factor-alpha

2003
[Effect of apoptosis induced by different vitamin E homologous analogues in human hepatoma cells(HepG2)].
    Wei sheng yan jiu = Journal of hygiene research, 2003, Volume: 32, Issue:4

    Topics: alpha-Tocopherol; Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; DNA, Neoplasm; Dose-Response Relationship, Drug; gamma-Tocopherol; Humans; Liver Neoplasms; Tocopherols; Tumor Cells, Cultured; Vitamin E

2003
Tissue-specificity of apoptosis in hepatoma-derived cell lines.
    Apoptosis : an international journal on programmed cell death, 2004, Volume: 9, Issue:3

    Topics: Acetylcysteine; alpha-Tocopherol; Animals; Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Culture Media, Serum-Free; Cycloheximide; Electrophoretic Mobility Shift Assay; Interleukin-1; Lipopolysaccharides; Liver Neoplasms; Protein Synthesis Inhibitors; Rats; Sorbitol; Transgenes; Tumor Necrosis Factor-alpha; Vinblastine; Vincristine

2004
Effect of carotenoids and ascorbic acid of Japanese persimmons on cellular lipid peroxidation in HepG2 cells.
    BioFactors (Oxford, England), 2004, Volume: 21, Issue:1-4

    Topics: alpha-Tocopherol; Antioxidants; Ascorbic Acid; Biological Transport; Carcinoma, Hepatocellular; Carotenoids; Cell Line, Tumor; Diospyros; Humans; Japan; Lipid Peroxidation; Liver Neoplasms; Plant Extracts; Thiobarbituric Acid Reactive Substances; Vitamin A

2004
Modulation of hepatic gene expression by alpha-tocopherol in cultured cells and in vivo.
    Annals of the New York Academy of Sciences, 2004, Volume: 1031

    Topics: alpha-Tocopherol; Animals; Carcinoma, Hepatocellular; Cells, Cultured; Gene Expression Regulation; Humans; Liver; Liver Neoplasms; Male; Nucleic Acid Hybridization; Oligonucleotide Array Sequence Analysis; Rats; Tumor Cells, Cultured

2004
Lycopene inhibits cell migration and invasion and upregulates Nm23-H1 in a highly invasive hepatocarcinoma, SK-Hep-1 cells.
    The Journal of nutrition, 2005, Volume: 135, Issue:9

    Topics: alpha-Tocopherol; Anticarcinogenic Agents; Antioxidants; beta Carotene; Carcinoma, Hepatocellular; Carotenoids; Cell Line, Tumor; Cell Movement; Drug Combinations; Humans; Liver Neoplasms; Lycopene; Neoplasm Invasiveness; NM23 Nucleoside Diphosphate Kinases; Nucleoside-Diphosphate Kinase; Oxidation-Reduction; RNA, Messenger; Up-Regulation

2005
Cytotoxicity and apoptosis produced by arachidonic acid in Hep G2 cells overexpressing human cytochrome P4502E1.
    The Journal of biological chemistry, 1997, Jun-06, Volume: 272, Issue:23

    Topics: alpha-Tocopherol; Antioxidants; Apoptosis; Ascorbic Acid; Aspirin; Carcinoma, Hepatocellular; Cell Survival; Chromans; Cytochrome P-450 CYP2E1; Deferoxamine; Humans; L-Lactate Dehydrogenase; Liver Neoplasms; Oleic Acid; Phenylenediamines; Propyl Gallate; Proto-Oncogene Proteins c-bcl-2; Recombinant Proteins; Transfection; Tumor Cells, Cultured; Vitamin E

1997
Vitamin E reduces chromosomal damage and inhibits hepatic tumor formation in a transgenic mouse model.
    Proceedings of the National Academy of Sciences of the United States of America, 2000, Feb-29, Volume: 97, Issue:5

    Topics: alpha-Tocopherol; Animals; Antioxidants; Dietary Supplements; Disease Models, Animal; DNA Damage; DNA, Mitochondrial; Liver; Liver Neoplasms; Mice; Mice, Inbred C57BL; Mice, Transgenic; Reactive Oxygen Species; Tocopherols; Vitamin E

2000
Role of vitamin E in the treatment of non-alcoholic steatohepatitis.
    Free radical biology & medicine, 2021, Volume: 177

    Topics: Antifibrotic Agents; Carcinoma, Hepatocellular; Humans; Liver; Liver Neoplasms; Non-alcoholic Fatty Liver Disease; Vitamin E

2021
Delta-tocotrienol enhances the anti-tumor effects of interferon alpha through reactive oxygen species and Erk/MAPK signaling pathways in hepatocellular carcinoma cells.
    Canadian journal of physiology and pharmacology, 2022, Volume: 100, Issue:5

    Topics: Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Humans; Interferon-alpha; Liver Neoplasms; Reactive Oxygen Species; Signal Transduction; Vitamin E

2022
[The National Consensus statement on the management of adult patients with non-alcoholic fatty liver disease and main comorbidities].
    Terapevticheskii arkhiv, 2022, Feb-15, Volume: 94, Issue:2

    Topics: Adult; Anti-Inflammatory Agents; Anticarcinogenic Agents; Antioxidants; Diabetes Mellitus, Type 2; Glucose; Humans; Inflammation; Lipids; Liver; Liver Neoplasms; Non-alcoholic Fatty Liver Disease; Thiazolidinediones; Ursodeoxycholic Acid; Vitamin E

2022
Formulation, Characterization And Evaluation Of Curcumin- Loaded PLGA- TPGS Nanoparticles For Liver Cancer Treatment.
    Drug design, development and therapy, 2019, Volume: 13

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Curcumin; Dose-Response Relationship, Drug; Drug Compounding; Drug Screening Assays, Antitumor; Hep G2 Cells; Humans; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred Strains; Molecular Structure; Polylactic Acid-Polyglycolic Acid Copolymer; Structure-Activity Relationship; Vitamin E

2019
Sorafenib-Loaded Nanoparticles Based on Biodegradable Dendritic Polymers for Enhanced Therapy of Hepatocellular Carcinoma.
    International journal of nanomedicine, 2020, Volume: 15

    Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Dendrimers; Drug Delivery Systems; Hep G2 Cells; Humans; Liver Neoplasms; Mice; Nanoparticles; Polymers; Sorafenib; Vitamin E; Xenograft Model Antitumor Assays

2020
Characterization and Cytotoxicity of Polyprenol Lipid and Vitamin E-TPGS Hybrid Nanoparticles for Betulinic Acid and Low-Substituted Hydroxyl Fullerenol in MHCC97H and L02 Cells.
    International journal of nanomedicine, 2020, Volume: 15

    Topics: Antineoplastic Agents; Betulinic Acid; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drug Delivery Systems; Drug Liberation; Fullerenes; Humans; Lipids; Liver Neoplasms; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Nanoparticles; Pentacyclic Triterpenes; Polyprenols; Triterpenes; Vitamin E

2020
Galactosylated TPGS Micelles for Docetaxel Targeting to Hepatic Carcinoma: Development, Characterization, and Biodistribution Study.
    AAPS PharmSciTech, 2020, Jun-16, Volume: 21, Issue:5

    Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Line, Tumor; Docetaxel; Drug Delivery Systems; Drug Development; Female; Galactose; Hep G2 Cells; Humans; Liver Neoplasms; Male; Random Allocation; Rats; Tissue Distribution; Vitamin E

2020
Biomimetic microbioreactor-supramolecular nanovesicles improve enzyme therapy of hepatic cancer.
    Nanomedicine : nanotechnology, biology, and medicine, 2021, Volume: 31

    Topics: 2-Hydroxypropyl-beta-cyclodextrin; Animals; Biomimetics; Enzyme Therapy; Humans; Hydrogen-Ion Concentration; Hydrolases; Liver Neoplasms; Vitamin E

2021
Folic acid modified TPGS as a novel nano-micelle for delivery of nitidine chloride to improve apoptosis induction in Huh7 human hepatocellular carcinoma.
    BMC pharmacology & toxicology, 2021, 01-06, Volume: 22, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Benzophenanthridines; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Drug Carriers; Drug Liberation; Folic Acid; Humans; Liver Neoplasms; Micelles; Nanoparticles; Vitamin E

2021
The chemoprotective effects of IFN-α-2b on rat hepatocarcinogenesis are blocked by vitamin E supplementation.
    The Journal of nutritional biochemistry, 2021, Volume: 96

    Topics: Animals; Anticarcinogenic Agents; Carcinogenesis; Drug Interactions; Interferon alpha-2; Liver; Liver Neoplasms; Male; Rats, Wistar; Vitamin E; Vitamins

2021
TPGS-Galactose-Modified Polydopamine Co-delivery Nanoparticles of Nitric Oxide Donor and Doxorubicin for Targeted Chemo-Photothermal Therapy against Drug-Resistant Hepatocellular Carcinoma.
    ACS applied materials & interfaces, 2021, Aug-04, Volume: 13, Issue:30

    Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Line, Tumor; Doxorubicin; Drug Carriers; Drug Liberation; Drug Resistance, Neoplasm; Drug Therapy; Galactose; Humans; Indoles; Infrared Rays; Liver Neoplasms; Male; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Nitric Oxide Donors; Nitroso Compounds; Photothermal Therapy; Polymers; Rats, Sprague-Dawley; Vitamin E; Xenograft Model Antitumor Assays

2021
Brefeldin A delivery nanomicelles in hepatocellular carcinoma therapy: Characterization, cytotoxic evaluation in vitro, and antitumor efficiency in vivo.
    Pharmacological research, 2021, Volume: 172

    Topics: Animals; Antineoplastic Agents; Apoptosis; Brefeldin A; Carcinoma, Hepatocellular; Cell Line; Cell Survival; Female; Humans; Liver Neoplasms; Mice, Inbred BALB C; Micelles; Nanostructures; Polyethylenes; Polypropylenes; Rats, Sprague-Dawley; Tissue Distribution; Vitamin E

2021
Redox-responsive PEGylated self-assembled prodrug-nanoparticles formed by single disulfide bond bridge periplocymarin-vitamin E conjugate for liver cancer chemotherapy.
    Drug delivery, 2017, Volume: 24, Issue:1

    Topics: Animals; Cardiac Glycosides; Disulfides; Humans; Liver Neoplasms; Mice; Nanoparticles; Oxidation-Reduction; Prodrugs; Vitamin E

2017
Star-shaped polymer of β‑cyclodextrin-g-vitamin E TPGS for doxorubicin delivery and multidrug resistance inhibition.
    Colloids and surfaces. B, Biointerfaces, 2018, 09-01, Volume: 169

    Topics: Animals; Antibiotics, Antineoplastic; beta-Cyclodextrins; Cell Proliferation; Cell Survival; Doxorubicin; Drug Delivery Systems; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Female; Humans; Liver Neoplasms; MCF-7 Cells; Mice; Mice, Inbred Strains; Molecular Structure; Particle Size; Polyethylene Glycols; Polymers; Succinates; Surface Properties; Tumor Cells, Cultured; Vitamin E

2018
N-acetylaminogalactosyl-decorated biodegradable PLGA-TPGS copolymer nanoparticles containing emodin for the active targeting therapy of liver cancer.
    Artificial cells, nanomedicine, and biotechnology, 2018, Volume: 46, Issue:sup2

    Topics: Apoptosis; Biological Transport; Drug Carriers; Emodin; Galactose; Hep G2 Cells; Humans; Liver Neoplasms; Molecular Targeted Therapy; Nanoparticles; Polylactic Acid-Polyglycolic Acid Copolymer; Vitamin E

2018
Weight Reduction and Pioglitazone are Cost-Effective for the Treatment of Non-Alcoholic Fatty Liver Disease in Thailand.
    PharmacoEconomics, 2019, Volume: 37, Issue:2

    Topics: Carcinoma, Hepatocellular; Cost-Benefit Analysis; Humans; Hypoglycemic Agents; Liver Cirrhosis; Liver Neoplasms; Markov Chains; Middle Aged; Non-alcoholic Fatty Liver Disease; Pioglitazone; Quality-Adjusted Life Years; Thailand; Vitamin E; Weight Loss; Weight Reduction Programs

2019
Codelivery of doxorubicin and elacridar to target both liver cancer cells and stem cells by polylactide-co-glycolide/d-alpha-tocopherol polyethylene glycol 1000 succinate nanoparticles.
    International journal of nanomedicine, 2018, Volume: 13

    Topics: Acridines; Animals; Carcinoma, Hepatocellular; Cell Death; Doxorubicin; Drug Delivery Systems; Drug Synergism; Endocytosis; Hep G2 Cells; Humans; Liver Neoplasms; Male; Mice, Nude; Nanoparticles; Neoplastic Stem Cells; Polyesters; Polyethylene Glycols; Rats, Sprague-Dawley; Stem Cell Transplantation; Stem Cells; Subcutaneous Tissue; Tetrahydroisoquinolines; Tissue Distribution; Tumor Stem Cell Assay; Vitamin E

2018
Therapeutic Effect of Sorafenib-Loaded TPGS-
    Journal of biomedical nanotechnology, 2018, Feb-01, Volume: 14, Issue:2

    Topics: Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Liver Neoplasms; Mice; Nanoparticles; Polyethylene Glycols; Sorafenib; Vitamin E

2018
γ-Tocotrienol attenuates triglyceride through effect on lipogenic gene expressions in mouse hepatocellular carcinoma Hepa 1-6.
    Journal of nutritional science and vitaminology, 2013, Volume: 59, Issue:2

    Topics: Animals; Carcinoma, Hepatocellular; Carnitine O-Palmitoyltransferase; Cell Line, Tumor; Cholesterol; Chromans; Fatty Acid Synthases; Gene Expression; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipogenesis; Liver Neoplasms; Mice; Mice, Inbred C57BL; RNA, Messenger; Stearoyl-CoA Desaturase; Sterol Regulatory Element Binding Protein 1; Triglycerides; Vitamin E

2013
JNK activation is required for TNFα-induced apoptosis in human hepatocarcinoma cells.
    International immunopharmacology, 2013, Volume: 17, Issue:1

    Topics: Anthracenes; Antioxidants; Apoptosis; Butylated Hydroxyanisole; Carcinoma, Hepatocellular; Caspases; Cell Line, Tumor; Chelating Agents; Cycloheximide; Deferoxamine; Humans; JNK Mitogen-Activated Protein Kinases; Liver Neoplasms; RNA Interference; RNA, Small Interfering; Signal Transduction; Tumor Necrosis Factor-alpha; Vitamin E

2013
Chitosan-g-TPGS nanoparticles for anticancer drug delivery and overcoming multidrug resistance.
    Molecular pharmaceutics, 2014, Jan-06, Volume: 11, Issue:1

    Topics: Animals; Antibiotics, Antineoplastic; Apoptosis; Blotting, Western; Breast Neoplasms; Carcinoma, Hepatocellular; Cell Proliferation; Chitosan; Doxorubicin; Drug Delivery Systems; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Flow Cytometry; Humans; Liver Neoplasms; Mice; Nanoparticles; Polyethylene Glycols; Polymers; Tissue Distribution; Tumor Cells, Cultured; Vitamin E; Xenograft Model Antitumor Assays

2014
Y-tocotrienol inhibits angiogenesis-dependent growth of human hepatocellular carcinoma through abrogation of AKT/mTOR pathway in an orthotopic mouse model.
    Oncotarget, 2014, Apr-15, Volume: 5, Issue:7

    Topics: Animals; Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Caspase 3; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Chick Embryo; Chromans; Endothelial Cells; Humans; Ki-67 Antigen; Liver Neoplasms; Mice; Mice, SCID; Models, Animal; Neovascularization, Pathologic; Proto-Oncogene Proteins c-akt; Signal Transduction; Vascular Endothelial Growth Factor A; Vitamin E

2014
Hydrogen-bonded and reduction-responsive micelles loading atorvastatin for therapy of breast cancer metastasis.
    Biomaterials, 2014, Volume: 35, Issue:26

    Topics: Animals; Atorvastatin; Breast; Breast Neoplasms; Cell Line, Tumor; Delayed-Action Preparations; Female; Heptanoic Acids; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver; Liver Neoplasms; Lung; Lung Neoplasms; Mice, Inbred BALB C; Mice, Nude; Micelles; Oxidation-Reduction; Polyethylene Glycols; Pyrroles; Vitamin E

2014
A novel oleanolic acid-loaded PLGA-TPGS nanoparticle for liver cancer treatment.
    Drug development and industrial pharmacy, 2015, Volume: 41, Issue:7

    Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Coumarins; Delayed-Action Preparations; Drug Carriers; Drug Liberation; Hep G2 Cells; Humans; Lactic Acid; Liver Neoplasms; Nanoparticles; Oleanolic Acid; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Solubility; Thiazoles; Vitamin E

2015
Nitric oxide releasing d-α-tocopheryl polyethylene glycol succinate for enhancing antitumor activity of doxorubicin.
    Molecular pharmaceutics, 2014, Nov-03, Volume: 11, Issue:11

    Topics: Animals; Antibiotics, Antineoplastic; Apoptosis; Carcinoma, Hepatocellular; Doxorubicin; Drug Carriers; Female; Half-Life; Hep G2 Cells; Humans; Liver Neoplasms; Mice; Micelles; Nitric Oxide; Polyethylene Glycols; Rats, Sprague-Dawley; Sarcoma 180; Tissue Distribution; Vitamin E

2014
TPGS-g-PLGA/Pluronic F68 mixed micelles for tanshinone IIA delivery in cancer therapy.
    International journal of pharmaceutics, 2014, Dec-10, Volume: 476, Issue:1-2

    Topics: Abietanes; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Biological Availability; Carcinoma, Hepatocellular; Delayed-Action Preparations; Drug Carriers; Drug Delivery Systems; Hep G2 Cells; Humans; Lactic Acid; Liver Neoplasms; Male; Micelles; Poloxamer; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Wistar; Serum Albumin, Bovine; Vitamin E

2014
Gamma-tocotrienol treatment increased peroxiredoxin-4 expression in HepG2 liver cancer cell line.
    BMC complementary and alternative medicine, 2015, Mar-13, Volume: 15

    Topics: Antineoplastic Agents; Antioxidants; Bile Duct Neoplasms; Chromans; Down-Regulation; Electrophoresis, Gel, Two-Dimensional; Hep G2 Cells; Hepatoblastoma; Humans; Liver; Liver Neoplasms; Peroxiredoxins; Proteins; Proteomics; Real-Time Polymerase Chain Reaction; RNA, Messenger; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tocotrienols; Up-Regulation; Vitamin E; Vitamins

2015
Genistein-loaded nanoparticles of star-shaped diblock copolymer mannitol-core PLGA-TPGS for the treatment of liver cancer.
    Materials science & engineering. C, Materials for biological applications, 2016, Volume: 59

    Topics: Animals; Drug Carriers; Genistein; Hep G2 Cells; Humans; Lactic Acid; Liver Neoplasms; Mannitol; Mice; Mice, SCID; Nanoparticles; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Vitamin E; Xenograft Model Antitumor Assays

2016
Improved antitumor activity of epirubicin-loaded CXCR4-targeted polymeric nanoparticles in liver cancers.
    International journal of pharmaceutics, 2016, Mar-16, Volume: 500, Issue:1-2

    Topics: Animals; Antibiotics, Antineoplastic; Cell Survival; Drug Liberation; Epirubicin; Hep G2 Cells; Humans; Lactic Acid; Liver Neoplasms; Mice; Microscopy, Electron, Transmission; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Treatment Outcome; Vitamin E

2016
Evaluation of TPGS-modified thermo-sensitive Pluronic PF127 hydrogel as a potential carrier to reverse the resistance of P-gp-overexpressing SMMC-7721 cell lines.
    Colloids and surfaces. B, Biointerfaces, 2016, Apr-01, Volume: 140

    Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Cell Line, Tumor; Cell Survival; Docetaxel; Drug Carriers; Drug Evaluation, Preclinical; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Hydrogel, Polyethylene Glycol Dimethacrylate; Liver Neoplasms; Mice, Inbred BALB C; Mice, Nude; Microscopy, Electron, Scanning; Poloxamer; Polyethylene Glycols; Taxoids; Temperature; Tumor Burden; Vitamin E; Xenograft Model Antitumor Assays

2016
Liver-targeting Resibufogenin-loaded poly(lactic-co-glycolic acid)-D-α-tocopheryl polyethylene glycol 1000 succinate nanoparticles for liver cancer therapy.
    International journal of nanomedicine, 2016, Volume: 11

    Topics: Animals; Antineoplastic Agents; Apoptosis; Bufanolides; Coumarins; Drug Carriers; Hep G2 Cells; Humans; Lactic Acid; Liver Neoplasms; Male; Mice; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats, Sprague-Dawley; Thiazoles; Vitamin E

2016
Emodin-Loaded PLGA-TPGS Nanoparticles Combined with Heparin Sodium-Loaded PLGA-TPGS Nanoparticles to Enhance Chemotherapeutic Efficacy Against Liver Cancer.
    Pharmaceutical research, 2016, Volume: 33, Issue:11

    Topics: Animals; Antimicrobial Cationic Peptides; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Survival; Drug Carriers; Drug Liberation; Emodin; Fluorescent Dyes; Heparin; Humans; Liver Neoplasms; Male; Mice; Nanoparticles; Particle Size; Surface Properties; Vitamin E

2016
Oleanolic acid-loaded PLGA-TPGS nanoparticles combined with heparin sodium-loaded PLGA-TPGS nanoparticles for enhancing chemotherapy to liver cancer.
    Life sciences, 2016, Nov-15, Volume: 165

    Topics: Animals; Antineoplastic Agents; Hep G2 Cells; Heparin; Humans; Lactic Acid; Liver Neoplasms; Mice; Nanoparticles; Oleanolic Acid; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Vitamin E

2016
δ and γ tocotrienols suppress human hepatocellular carcinoma cell proliferation via regulation of Ras-Raf-MEK-ERK pathway-associated upstream signaling.
    Food & function, 2016, Oct-12, Volume: 7, Issue:10

    Topics: Carcinoma, Hepatocellular; Cell Proliferation; Chromans; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Liver Neoplasms; MAP Kinase Kinase Kinases; raf Kinases; ras Proteins; Signal Transduction; Vitamin E

2016
Coenzyme Q10 and Oxidative Stress: Inflammation Status in Hepatocellular Carcinoma Patients after Surgery.
    Nutrients, 2017, Jan-04, Volume: 9, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Aspartate Aminotransferases; Blood Glucose; C-Reactive Protein; Carcinoma, Hepatocellular; Creatinine; Glutathione Peroxidase; Humans; Inflammation; Interleukin-6; Linear Models; Liver Neoplasms; Malondialdehyde; Middle Aged; Oxidative Stress; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Tumor Necrosis Factor-alpha; Ubiquinone; Vitamin E; Young Adult

2017
Evaluation of redox statuses in patients with hepatitis B virus-associated hepatocellular carcinoma.
    Annals of clinical biochemistry, 2009, Volume: 46, Issue:Pt 5

    Topics: Adult; Aged; Aged, 80 and over; Ascorbic Acid; Carcinoma, Hepatocellular; Female; Glutathione; Glutathione Disulfide; Glutathione Peroxidase; Glutathione Reductase; Hepatitis B; Hepatitis B virus; Humans; Liver Neoplasms; Male; Malondialdehyde; Middle Aged; Oxidation-Reduction; Superoxide Dismutase; Vitamin A; Vitamin E

2009
No association between fruit, vegetables, antioxidant nutrients and risk of renal cell carcinoma.
    International journal of cancer, 2010, Mar-15, Volume: 126, Issue:6

    Topics: Aged; Antioxidants; Ascorbic Acid; Carcinoma, Renal Cell; Carotenoids; Diet; Finland; Flavonoids; Fruit; Humans; Liver Neoplasms; Male; Middle Aged; Multivariate Analysis; Prospective Studies; Risk Factors; Smoking; Surveys and Questionnaires; Vegetables; Vitamin E

2010
Gamma delta tocotrienols reduce hepatic triglyceride synthesis and VLDL secretion.
    Journal of atherosclerosis and thrombosis, 2010, Oct-27, Volume: 17, Issue:10

    Topics: Animals; Apolipoprotein B-100; Blotting, Western; Carcinoma, Hepatocellular; Cell Proliferation; Cells, Cultured; Chromans; Diacylglycerol O-Acyltransferase; Female; Humans; Hydroxymethylglutaryl CoA Reductases; Lipoproteins, VLDL; Liver; Liver Neoplasms; Male; Mice; Mice, Knockout; Receptors, LDL; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sterol Regulatory Element Binding Protein 1; Sterol Regulatory Element Binding Protein 2; Triglycerides; Vitamin E

2010
γ-Tocotrienol is a novel inhibitor of constitutive and inducible STAT3 signalling pathway in human hepatocellular carcinoma: potential role as an antiproliferative, pro-apoptotic and chemosensitizing agent.
    British journal of pharmacology, 2011, Volume: 163, Issue:2

    Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Chromans; Doxorubicin; Drug Resistance, Neoplasm; Drug Synergism; Enzyme Activation; Enzyme Induction; Genes, Reporter; Humans; Janus Kinases; Liver Neoplasms; NF-kappa B; Paclitaxel; Phosphorylation; Protein Kinase Inhibitors; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins c-akt; Signal Transduction; src-Family Kinases; STAT3 Transcription Factor; Vitamin E

2011
Relationships between blood levels of fat soluble vitamins and disease etiology and severity in adults awaiting liver transplantation.
    Journal of gastroenterology and hepatology, 2011, Volume: 26, Issue:9

    Topics: Adolescent; Adult; Avitaminosis; Biomarkers; Calcifediol; Carcinoma, Hepatocellular; Cholestasis; Cross-Sectional Studies; End Stage Liver Disease; Female; Humans; Least-Squares Analysis; Liver Neoplasms; Liver Transplantation; Male; Middle Aged; Nutritional Status; Prospective Studies; Queensland; Regression Analysis; Risk Assessment; Risk Factors; Severity of Illness Index; Solubility; Vitamin A; Vitamin E; Vitamins; Waiting Lists; Young Adult

2011
[Prognosis and treatment of non-alcoholic fatty liver disease and steatohepatitis].
    Ugeskrift for laeger, 2012, Feb-20, Volume: 174, Issue:8

    Topics: Fatty Liver; Humans; Hypoglycemic Agents; Liver Cirrhosis; Liver Neoplasms; Pioglitazone; Prognosis; Risk Factors; Thiazolidinediones; Vitamin E

2012
Formulation, antileukemia mechanism, pharmacokinetics, and biodistribution of a novel liposomal emodin.
    International journal of nanomedicine, 2012, Volume: 7

    Topics: Animals; Antineoplastic Agents; Blotting, Western; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Emodin; Female; Humans; Leukemia L1210; Liposomes; Liver Neoplasms; Male; Mice; Mice, Inbred ICR; Particle Size; Phosphatidylethanolamines; Polyethylene Glycols; Random Allocation; Tissue Distribution; Transferrin; Vitamin E

2012
Vitamin intake and liver cancer risk: a report from two cohort studies in China.
    Journal of the National Cancer Institute, 2012, Aug-08, Volume: 104, Issue:15

    Topics: Adult; Aged; Antioxidants; Ascorbic Acid; Calcium Compounds; China; Cohort Studies; Dietary Supplements; Feeding Behavior; Female; Humans; Liver Neoplasms; Male; Middle Aged; Odds Ratio; Proportional Hazards Models; Prospective Studies; Surveys and Questionnaires; Vitamin E; Vitamins

2012
Vitamin E succinate inhibits colon cancer liver metastases.
    The Journal of surgical research, 2002, Volume: 106, Issue:2

    Topics: Animals; Apoptosis; Carcinoma; Cell Division; Colonic Neoplasms; Liver; Liver Neoplasms; Mice; Tocopherols; Tumor Cells, Cultured; Vitamin E

2002
Effect of tea catechins on cellular lipid peroxidation and cytotoxicity in HepG2 cells.
    Bioscience, biotechnology, and biochemistry, 2002, Volume: 66, Issue:7

    Topics: Antineoplastic Agents, Phytogenic; Catechin; Dose-Response Relationship, Drug; Enzyme Activation; Glutathione; Glutathione Disulfide; Glutathione Peroxidase; Humans; Lipid Peroxidation; Liver Neoplasms; Tea; tert-Butylhydroperoxide; Thiobarbituric Acid Reactive Substances; Tumor Cells, Cultured; Vitamin E

2002
Effect of beta-carotene supplementation on rats submitted to chronic ethanol ingestion.
    Drug and chemical toxicology, 2003, Volume: 26, Issue:3

    Topics: Animals; Antioxidants; beta Carotene; Body Weight; Cytochrome P-450 CYP2E1; Drug Administration Schedule; Eating; Ethanol; Glutathione; Liver; Liver Neoplasms; Male; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances; Time Factors; Vitamin E

2003
Acquired tolerance of hepatocellular carcinoma cells to selenium deficiency: a selective survival mechanism?
    Cancer research, 2003, Oct-15, Volume: 63, Issue:20

    Topics: Adaptation, Physiological; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Genome, Viral; Hepatitis B virus; Humans; Liver Neoplasms; Oxidative Stress; Selenium; Vitamin E

2003
Tocopherol in tumor tissues and effects of tocopherol on the development of liver tumors.
    Cancer research, 1951, Volume: 11, Issue:12

    Topics: Humans; Liver Neoplasms; Neoplasms; Tocopherols; Vitamin E

1951
Re: Selenium supplementation and secondary prevention of nonmelanoma skin cancer in a randomized trial.
    Journal of the National Cancer Institute, 2004, Feb-18, Volume: 96, Issue:4

    Topics: Administration, Cutaneous; Administration, Oral; Aged; Animals; Anticarcinogenic Agents; Antioxidants; DNA Damage; Drug Therapy, Combination; Female; Hematologic Neoplasms; Humans; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Neoplasms; Prostatic Neoplasms; Randomized Controlled Trials as Topic; Rats; Rats, Inbred Strains; Selenium Compounds; Skin Neoplasms; Testicular Neoplasms; Vitamin E

2004
Comparison of vitamin E derivatives alpha-TEA and VES in reduction of mouse mammary tumor burden and metastasis.
    Experimental biology and medicine (Maywood, N.J.), 2004, Volume: 229, Issue:9

    Topics: Animals; Cell Line, Tumor; Female; In Situ Nick-End Labeling; Liver Neoplasms; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C57BL; Tocopherols; Vitamin E

2004
Vitamin E down-modulates iNOS and NADPH oxidase in c-Myc/TGF-alpha transgenic mouse model of liver cancer.
    Journal of hepatology, 2004, Volume: 41, Issue:5

    Topics: Animals; Antioxidants; Disease Models, Animal; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; HSP70 Heat-Shock Proteins; Liver Neoplasms; Male; Membrane Proteins; Mice; Mice, Transgenic; NADPH Oxidases; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Proto-Oncogene Proteins c-myc; Transforming Growth Factor alpha; Tyrosine; Vitamin E

2004
Dietary vitamin E does not inhibit the promotion of liver carcinogenesis by polychlorinated biphenyls in rats.
    The Journal of nutrition, 2005, Volume: 135, Issue:2

    Topics: Animals; Diet; Female; Liver; Liver Neoplasms; NF-kappa B; Polychlorinated Biphenyls; Rats; Rats, Sprague-Dawley; Vitamin E

2005
Effects of the antioxidative vitamins A, C and E on liver metastasis and intrametastatic lipid peroxidation in BOP-induced pancreatic cancer in Syrian hamsters.
    Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], 2005, Volume: 5, Issue:4-5

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antioxidants; Ascorbic Acid; Carcinoma, Pancreatic Ductal; Cricetinae; Disease Models, Animal; Glutathione Peroxidase; Lipid Peroxidation; Liver Neoplasms; Male; Mesocricetus; Neoplasm Metastasis; Nitrosamines; Pancreatic Neoplasms; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Vitamin A; Vitamin E

2005
Effects of antioxidants and caspase-3 inhibitor on the phenylethyl isothiocyanate-induced apoptotic signaling pathways in human PLC/PRF/5 cells.
    European journal of pharmacology, 2005, Aug-22, Volume: 518, Issue:2-3

    Topics: Acetylcysteine; Antioxidants; Apoptosis; Apoptosis Regulatory Proteins; Apoptotic Protease-Activating Factor 1; bcl-2-Associated X Protein; BH3 Interacting Domain Death Agonist Protein; Blotting, Western; Carcinoma, Hepatocellular; Carrier Proteins; Caspase 3; Caspase 8; Caspase 9; Caspase Inhibitors; Caspases; Cell Line, Tumor; Cell Proliferation; Cysteine Proteinase Inhibitors; Cytochromes c; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Activation; fas Receptor; Flow Cytometry; Humans; Intracellular Membranes; Intracellular Signaling Peptides and Proteins; Isothiocyanates; Liver Neoplasms; Membrane Potentials; Mitochondria; Mitochondrial Proteins; Oligopeptides; Proteins; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Time Factors; Tumor Suppressor Protein p53; Up-Regulation; Vitamin E; X-Linked Inhibitor of Apoptosis Protein

2005
Apoptosis induction by gamma-tocotrienol in human hepatoma Hep3B cells.
    The Journal of nutritional biochemistry, 2006, Volume: 17, Issue:10

    Topics: Apoptosis; Carcinoma, Hepatocellular; Caspase 3; Caspase 8; Caspase 9; Caspases; Cell Division; Cell Line, Tumor; Chromans; Gene Expression; Genes, bcl-2; Humans; Liver Neoplasms; Poly(ADP-ribose) Polymerases; Tocotrienols; Vitamin E

2006
Hepatocellular carcinoma with peritoneal dissemination which was regressed during vitamin K2 and vitamin E administration.
    Internal medicine (Tokyo, Japan), 2007, Volume: 46, Issue:11

    Topics: Aged; Apoptosis; Carcinoma, Hepatocellular; Combined Modality Therapy; Drug Therapy, Combination; Embolization, Therapeutic; Humans; Liver Neoplasms; Male; Neoplasm Seeding; Peritoneal Neoplasms; Rupture, Spontaneous; Vitamin E; Vitamin K 2; Vitamins

2007
alpha-Tocopherol level in liver diseases.
    Acta vitaminologica et enzymologica, 1982, Volume: 4, Issue:4

    Topics: Adolescent; Adult; Cholesterol; Hepatitis; Hepatitis, Alcoholic; Humans; Lipoproteins, LDL; Liver Cirrhosis; Liver Diseases; Liver Function Tests; Liver Neoplasms; Middle Aged; Phospholipids; Vitamin E

1982
[The role of alpha-tocopherol and retinol in correcting disorders of lipid peroxidation in patients with malignant liver neoplasms].
    Voprosy onkologii, 1995, Volume: 41, Issue:1

    Topics: Adenoma, Bile Duct; Carcinoma, Hepatocellular; Combined Modality Therapy; Humans; Lipid Peroxidation; Liver Neoplasms; Postoperative Complications; Vitamin A; Vitamin E

1995
Chemopreventive effects of beta-carotene, alpha-tocopherol and five naturally occurring antioxidants on initiation of hepatocarcinogenesis by 2-amino-3-methylimidazo[4,5-f]quinoline in the rat.
    Japanese journal of cancer research : Gann, 1994, Volume: 85, Issue:12

    Topics: Allyl Compounds; Animals; Anticarcinogenic Agents; Antioxidants; Benzaldehydes; beta Carotene; Carcinogens; Carotenoids; Food Contamination; Glutathione; Liver Neoplasms; Male; Quercetin; Quinolines; Rats; Rats, Inbred F344; Sulfides; Vitamin E

1994
Decreased activity of scavenger enzymes in human hepatocellular carcinoma, but not in liver metastases.
    International journal of clinical & laboratory research, 1994, Volume: 24, Issue:2

    Topics: Adult; Aged; Carcinoma, Hepatocellular; Chromatography, High Pressure Liquid; Female; Glutathione Peroxidase; Humans; Liver; Liver Neoplasms; Male; Middle Aged; Selenium; Superoxide Dismutase; Vitamin A; Vitamin E

1994
Bromobenzene detoxification in the human liver-derived HepG2 cell line.
    Xenobiotica; the fate of foreign compounds in biological systems, 1994, Volume: 24, Issue:3

    Topics: Antipain; Bromobenzenes; Carcinoma, Hepatocellular; Cell Survival; Culture Media; Cytochrome P-450 Enzyme System; Epoxide Hydrolases; Free Radicals; Glutathione; Humans; Inactivation, Metabolic; Lipid Peroxidation; Liver; Liver Neoplasms; Models, Biological; Prostaglandin-Endoperoxide Synthases; Tumor Cells, Cultured; Vitamin E

1994
Vitamin A, Vitamin E or beta-carotene status and hepatitis B-related hepatocellular carcinoma.
    Annals of epidemiology, 1993, Volume: 3, Issue:3

    Topics: Adult; beta Carotene; Carcinoma, Hepatocellular; Carotenoids; Case-Control Studies; Diet; Hepatitis B; Humans; Liver Neoplasms; Male; Middle Aged; Odds Ratio; Risk Factors; Socioeconomic Factors; Vitamin A; Vitamin E

1993
Tocotrienols regulate cholesterol production in mammalian cells by post-transcriptional suppression of 3-hydroxy-3-methylglutaryl-coenzyme A reductase.
    The Journal of biological chemistry, 1993, May-25, Volume: 268, Issue:15

    Topics: Acetates; Acetic Acid; Androstenes; Animals; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Line; Chickens; CHO Cells; Cholesterol; Chromans; Cricetinae; Gene Expression Regulation, Enzymologic; Humans; Hydroxycholesterols; Hydroxymethylglutaryl CoA Reductases; Ketoconazole; Kinetics; Liver Neoplasms; Liver Neoplasms, Experimental; Lovastatin; Mevalonic Acid; Rats; RNA Processing, Post-Transcriptional; RNA, Messenger; Suppression, Genetic; Tritium; Tumor Cells, Cultured; Vitamin E

1993
Alpha-tocopherol protects against a reduction in adenosylcobalamin in oxidatively stressed human cells.
    The Journal of nutrition, 1993, Volume: 123, Issue:7

    Topics: Carcinoma, Hepatocellular; Cells, Cultured; Cobamides; Fibroblasts; Humans; Linoleic Acid; Linoleic Acids; Lipid Peroxidation; Liver Neoplasms; Oxidation-Reduction; Tumor Cells, Cultured; Vitamin E

1993
An in vitro system for identifying agents capable of changing serum lipoprotein(a) concentration by regulating the transcriptional activity of the apolipoprotein(a) gene promoter.
    Biochemical and biophysical research communications, 1996, Oct-14, Volume: 227, Issue:2

    Topics: Adult; Apolipoproteins; Apoprotein(a); Base Sequence; Cell Line; Danazol; DNA; DNA Primers; Female; Gene Expression Regulation, Neoplastic; Genes, Reporter; Hepatoblastoma; Humans; Interleukin-6; Kinetics; Leukemia, Promyelocytic, Acute; Lipoprotein(a); Liver Neoplasms; Luciferases; Male; Middle Aged; Promoter Regions, Genetic; Recombinant Fusion Proteins; Transcription, Genetic; Transfection; Tretinoin; Triiodothyronine; Tumor Cells, Cultured; Vitamin E

1996
Oxidative modification of low-density lipoprotein by the human hepatoma cell line HepG2.
    Free radical research, 1996, Volume: 25, Issue:4

    Topics: Antioxidants; Butylated Hydroxytoluene; Chromatography, Ion Exchange; Electrophoresis, Agar Gel; Electrophoresis, Polyacrylamide Gel; Hepatoblastoma; Humans; Lipid Peroxidation; Lipoproteins, LDL; Liver Neoplasms; Oxidation-Reduction; Probucol; Superoxides; Thiobarbituric Acid Reactive Substances; Tumor Cells, Cultured; Vitamin E

1996
Rapid loss in the mitochondrial membrane potential during geranylgeranoic acid-induced apoptosis.
    Biochemical and biophysical research communications, 1997, Jan-03, Volume: 230, Issue:1

    Topics: Animals; Apoptosis; Carcinoma, Hepatocellular; Caspase 1; Cell Line; Cysteine Endopeptidases; Diterpenes; Fluorescent Dyes; Humans; Intracellular Membranes; Kinetics; Liver; Liver Neoplasms; Membrane Potentials; Mice; Mitochondria; Mitochondria, Liver; Rhodamine 123; Rhodamines; Time Factors; Tumor Cells, Cultured; Vitamin E

1997
Human lipoproteins as a vehicle for the delivery of beta-carotene and alpha-tocopherol to HepG2 cells.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1997, Volume: 214, Issue:4

    Topics: Adult; beta Carotene; Carcinoma, Hepatocellular; Culture Media, Serum-Free; Drug Carriers; Humans; Lipoproteins; Liver; Liver Neoplasms; Male; Micelles; Middle Aged; Tumor Cells, Cultured; Vitamin E

1997
No inhibition of gamma-glutamyl transpeptidase-positive foci by vitamin E with or without phenobarbital.
    Nutrition and cancer, 1997, Volume: 27, Issue:2

    Topics: Animals; Dinoprost; Fatty Acids; Female; Fish Oils; gamma-Glutamyltransferase; Glutathione Transferase; Lipid Peroxidation; Liver; Liver Neoplasms; Organ Size; Phenobarbital; Phospholipids; Pregnancy; Rats; Rats, Sprague-Dawley; Vitamin E

1997
Correlation of repressed transcription of alpha-tocopherol transfer protein with serum alpha-tocopherol during hepatocarcinogenesis.
    International journal of cancer, 1997, May-16, Volume: 71, Issue:4

    Topics: Aged; Animals; Carcinogens; Carcinoma, Hepatocellular; Carrier Proteins; Cholesterol; Diethylnitrosamine; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Humans; Hyperplasia; Liver; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Middle Aged; Neoplasm Proteins; Rats; Rats, Wistar; RNA, Messenger; RNA, Neoplasm; Transcription, Genetic; Vitamin A; Vitamin E; Vitamin E Deficiency

1997
Hepatic tocopherol content in primary hepatocellular carcinoma and liver metastases.
    Hepatology (Baltimore, Md.), 1997, Volume: 26, Issue:1

    Topics: Aged; beta Carotene; Carcinoma, Hepatocellular; Carotenoids; Female; Humans; Lipids; Liver; Liver Neoplasms; Male; Middle Aged; Vitamin A; Vitamin E

1997
Plasma antioxidant vitamins, chronic hepatitis B virus infection and urinary aflatoxin B1-DNA adducts in healthy males.
    Carcinogenesis, 1997, Volume: 18, Issue:6

    Topics: Adult; Aflatoxin B1; Aged; Antioxidants; beta Carotene; Carotenoids; Chronic Disease; DNA; DNA Adducts; Guanine; Hepatitis B; Hepatitis B Surface Antigens; Hepatitis B virus; Humans; Liver; Liver Neoplasms; Male; Middle Aged; Testosterone; Vitamin E; Vitamins

1997
Plasma ratio of ubiquinol and ubiquinone as a marker of oxidative stress.
    Molecular aspects of medicine, 1997, Volume: 18 Suppl

    Topics: Biomarkers; Carcinoma, Hepatocellular; Chromatography, High Pressure Liquid; Coenzymes; Electrochemistry; Hepatitis; Hexanes; Humans; Liver Cirrhosis; Liver Diseases; Liver Neoplasms; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Solvents; Ubiquinone; Vitamin E

1997
Vitamins C, E and A and heme oxygenase in rats fed methyl/folate-deficient diets.
    Free radical biology & medicine, 1997, Volume: 23, Issue:6

    Topics: Animals; Ascorbic Acid; Carcinoma, Hepatocellular; Choline Deficiency; Folic Acid Deficiency; Heme Oxygenase (Decyclizing); Liver Neoplasms; Male; Methionine; Niacin; Oxidative Stress; Rats; Rats, Inbred F344; Vitamin A; Vitamin E; Vitamin E Deficiency; Vitamins; Weight Gain

1997
Enhancing effect of thoraco-laparotomy on liver metastasis and the role played by active oxygens in its mechanism.
    Surgery today, 1997, Volume: 27, Issue:11

    Topics: Animals; Antioxidants; Ascorbic Acid; Carcinoma, Hepatocellular; Free Radical Scavengers; Laparotomy; Lipid Peroxides; Liver Neoplasms; Male; Mice; Neoplasm Metastasis; Oxidative Stress; Rats; Rats, Inbred Strains; Tumor Cells, Cultured; Vitamin E

1997
Oxidative stress in patients with hepatitis, cirrhosis, and hepatoma evaluated by plasma antioxidants.
    Biochemical and biophysical research communications, 1998, Jun-09, Volume: 247, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antioxidants; Ascorbic Acid; beta Carotene; Biomarkers; Carcinoma, Hepatocellular; Carotenoids; Cholesterol; Cholesterol Esters; Female; Hepatitis, Chronic; Humans; Liver Cirrhosis; Liver Diseases; Liver Neoplasms; Lycopene; Male; Middle Aged; Oxidative Stress; Ubiquinone; Vitamin E

1998
Growth modulating effects of chlorinated oleic acid in cell cultures.
    Pharmacology & toxicology, 1998, Volume: 83, Issue:1

    Topics: Albumins; Animals; Carcinoma, Hepatocellular; Cell Count; Cell Division; Cell Line; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Endothelium, Vascular; Epithelial Cells; Humans; Kidney; Liver Neoplasms; Stearic Acids; Vitamin E

1998
Serum retinol and alpha-tocopherol levels in healthy Asian subjects and patients.
    Annals of clinical biochemistry, 1999, Volume: 36 ( Pt 2)

    Topics: Breast Neoplasms; Colonic Neoplasms; Coronary Disease; Diabetes Mellitus; Heart Diseases; Humans; Infant, Newborn; Kidney Diseases; Leukemia; Liver Neoplasms; Pancreatic Neoplasms; Singapore; Vitamin A; Vitamin E

1999
Plasma ubiquinone to ubiquinol ratio in patients with hepatitis, cirrhosis, and hepatoma, and in patients treated with percutaneous transluminal coronary reperfusion.
    BioFactors (Oxford, England), 1999, Volume: 9, Issue:2-4

    Topics: Adult; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Ascorbic Acid; beta Carotene; Bilirubin; Biomarkers; Carcinoma, Hepatocellular; Carotenoids; Female; Hepatitis; Humans; Liver Cirrhosis; Liver Neoplasms; Lycopene; Male; Middle Aged; Oxidative Stress; Reference Values; Ubiquinone; Uric Acid; Vitamin E

1999
Mechanisms of cancer chemoprevention in hepatic carcinogenesis: modulation of focal lesion growth in mice.
    Toxicological sciences : an official journal of the Society of Toxicology, 1999, Volume: 52, Issue:2 Suppl

    Topics: Animals; Antioxidants; Apoptosis; DNA Replication; Liver; Liver Neoplasms; Male; Mice; Oxidative Stress; Tea; Vitamin E

1999
Induction of catalase, alpha, and microsomal glutathione S-transferase in CYP2E1 overexpressing HepG2 cells and protection against short-term oxidative stress.
    Hepatology (Baltimore, Md.), 2001, Volume: 33, Issue:3

    Topics: Aldehydes; Carcinoma, Hepatocellular; Catalase; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Enzyme Induction; Extracellular Space; Glutathione Transferase; Humans; Hydrogen Peroxide; Isoenzymes; Liver Neoplasms; Microsomes, Liver; Mixed Function Oxygenases; Oxidants; Oxidative Stress; RNA, Messenger; Tumor Cells, Cultured; Vitamin E

2001
Effects of ascorbic acid and DL-alpha-tocopherol on human hepatoma cell proliferation and redifferentiation.
    Acta pharmacologica Sinica, 2000, Volume: 21, Issue:4

    Topics: alpha-Fetoproteins; Ascorbic Acid; Carcinoma, Hepatocellular; Cell Differentiation; Cell Division; gamma-Glutamyltransferase; Humans; Liver Neoplasms; Tumor Cells, Cultured; Vitamin E

2000
Decreased disappearance rate of 1-(2-tetrahydrofuryl)-5-fluorouracil (FT-207) from the blood and its unresponsiveness to tocophreyl nicotinate and indomethacin in patients with primary hepatocellular carcinoma.
    Acta medica Okayama, 1979, Volume: 33, Issue:5

    Topics: Carcinoma, Hepatocellular; Fluorouracil; Humans; Indomethacin; Kinetics; Liver Cirrhosis; Liver Neoplasms; Microsomes, Liver; Nicotinic Acids; Tegafur; Vitamin E

1979
[Studies on lysosomes in hepatic disorders (author's transl)].
    [Hokkaido igaku zasshi] The Hokkaido journal of medical science, 1979, Volume: 54, Issue:2

    Topics: Acid Phosphatase; Animals; Chemical and Drug Induced Liver Injury; Chloroquine; Glucuronidase; Hexosaminidases; Humans; Jaundice; Liver Diseases; Liver Neoplasms; Lysosomes; Male; Rats; Vitamin E

1979
Growth inhibition of human hepatoma cells (HepG2) by polyunsaturated fatty acids. Protection by albumin and vitamin E.
    Acta physiologica Scandinavica, 1992, Volume: 144, Issue:1

    Topics: Albumins; Carcinoma, Hepatocellular; Cell Division; Fatty Acids, Unsaturated; Humans; In Vitro Techniques; Lipoproteins, VLDL; Liver Neoplasms; Tumor Cells, Cultured; Vitamin E

1992
Lack of modification by naturally occurring antioxidants of 3,2'-dimethyl-4-aminobiphenyl-initiated rat prostate carcinogenesis.
    Cancer letters, 1991, Jul-04, Volume: 58, Issue:3

    Topics: Aminobiphenyl Compounds; Animals; Antioxidants; Carcinogens; Catechols; Hydroquinones; Hyperplasia; Hypolipidemic Agents; Intestinal Neoplasms; Liver Neoplasms; Male; Pancreatic Neoplasms; Phenylpropionates; Prostatic Neoplasms; Rats; Rats, Inbred F344; Resorcinols; Selenium; Testicular Neoplasms; Vitamin E

1991
Levels of vitamin A and cellular retinol binding protein in human hepatocellular carcinoma and adjacent normal tissue.
    Nutrition and cancer, 1989, Volume: 12, Issue:4

    Topics: Adult; Aged; Carcinoma, Hepatocellular; Female; Humans; Liver; Liver Neoplasms; Male; Middle Aged; Prospective Studies; Retinol-Binding Proteins; Retinol-Binding Proteins, Cellular; Vitamin A; Vitamin E

1989
Vitamins E and K induce aryl hydrocarbon hydroxylase activity in human cell cultures.
    Biochemical and biophysical research communications, 1987, Mar-30, Volume: 143, Issue:3

    Topics: Aryl Hydrocarbon Hydroxylases; Breast Neoplasms; Carcinoma, Hepatocellular; Cell Line; Enzyme Induction; Humans; Kinetics; Liver Neoplasms; Vitamin E; Vitamin K

1987
Differential modification of development of preneoplastic lesions in the Syrian golden hamster initiated with a single dose of 2,2'-dioxo-N-nitrosodipropylamine: influence of subsequent butylated hydroxyanisole, alpha-tocopherol, or carbazole.
    Journal of the National Cancer Institute, 1987, Volume: 78, Issue:2

    Topics: Animals; Butylated Hydroxyanisole; Carbazoles; Carcinogens; Cricetinae; Liver Neoplasms; Mesocricetus; Nitrosamines; Pancreatic Neoplasms; Precancerous Conditions; Vitamin E

1987
Biochemical, pathological, and genetic aspects of a spontaneous mouse hepatoma.
    Journal of the National Cancer Institute, 1969, Volume: 43, Issue:2

    Topics: Age Factors; Animals; Carcinoma, Hepatocellular; Diet; Fatty Liver; Female; Hybridization, Genetic; Karyotyping; L-Serine Dehydratase; Liver; Liver Neoplasms; Male; Methylation; Mice; Neoplasms, Experimental; Rats; RNA, Transfer; Sex Factors; Transaminases; Transferases; Vitamin E

1969
Effect of dietary selenium on N-2 fluorenyl-acetamide (FAA)-induced cancer in vitamin E supplemented, selenium depleted rats.
    Clinical toxicology, 1972, Volume: 5, Issue:2

    Topics: Adenocarcinoma; Animals; Chemical and Drug Induced Liver Injury; Deficiency Diseases; Diet; Female; Fluorenes; Liver Neoplasms; Mammary Neoplasms, Experimental; Neoplasms, Experimental; Rats; Rats, Inbred Strains; Selenium; Time Factors; Vitamin E

1972