Page last updated: 2024-08-21

d-alpha tocopherol and Idiopathic Parkinson Disease

d-alpha tocopherol has been researched along with Idiopathic Parkinson Disease in 121 studies

Research

Studies (121)

TimeframeStudies, this research(%)All Research%
pre-199013 (10.74)18.7374
1990's54 (44.63)18.2507
2000's23 (19.01)29.6817
2010's19 (15.70)24.3611
2020's12 (9.92)2.80

Authors

AuthorsStudies
Hall, J; Johnson, L; Mason, D; O'Bryant, SE; Petersen, M; Zhang, F1
Auinger, P; Christine, CW; Green, R; Joslin, A; Yelpaala, Y1
Auinger, P; Cain, KC; Cholerton, B; Ginghina, C; Liu, C; Shi, M; Stewart, T; Zhang, J1
Knoll, B; Knoll, J; Miklya, I1
Fariss, MW; Zhang, JG1
Arlt, S; Beisiegel, U; Buhmann, C; Kontush, A; Möller-Bertram, T; Oechsner, M; Sperber, S; Stuerenburg, HJ1
Cai, HB; Ge, ZM; Zhao, CC1
Ghoreishy, SM; Jayedi, A; Mohammadi, H; Talebi, S; Travica, N1
Abbas, AN; Abd-Elhaleim El Azazy, MK; Abdel Hady, MMM; Abu-Elfotuh, K; Alahmre, ATS; Ali, AA; Awny, MM; El-Sisi, AM; Elewa, MAF; Hamdan, AME; Hassan, FAM; Kamal, MM; Khalil, MG; Masoud, RAE; Othman, M; Wahid, A1
Ahari, SG; Rahnemayan, S; Rikhtegar, R; Riyahifar, S; Sanaie, S1
Chen, GS; Chen, JX; Gao, H; Gao, QH; Huo, JH; Pang, YF; Wu, LY1
Bhuvanendran, S; Magalingam, KB; Radhakrishnan, AK; Ramdas, P; Selvaduray, KR; Somanath, SD1
Ahmad, R; Ali, J; Atiq, A; Choe, K; Kang, MH; Khan, A; Kim, MO; Lee, HJ; Park, JS; Rehman, IU; Tahir, M1
Matsura, T1
Jin, A; Khan, S; Koh, WP; Tan, EK; Tan, LCS; Wong, ASY; Wu, Y; Ying, AF; Yuan, JM1
Adami, HO; Bellocco, R; Bonn, S; Hantikainen, E; Serafini, M; Trolle Lagerros, Y; Ye, W1
Arslan, N; Gezmen-Karadag, M; Icer, MA1
Chang, MC; Kwak, S; Kwak, SG1
Aarabi, MH; Abolhassani, J; Asemi, Z; Bahmani, F; Dadgostar, E; Daneshvar Kakhaki, R; Kouchaki, E; Memarzadeh, MR; Taghizadeh, M; Tamtaji, OR1
Håkansson, N; Pedersen, NL; Wirdefeldt, K; Wolk, A; Yang, F1
Abolhassani, J; Aghadavod, E; Asemi, Z; Dadgostar, E; Daneshvar Kakhaki, R; Mafi, A; Taghizadeh, M; Tamtaji, OR1
Alam, T; Ali, J; Baboota, S; Gaba, B; Haider, MF; Khan, T; Parvez, S1
Armstrong, NJ; Brodaty, H; Coupland, KG; Dobson-Stone, C; Halliday, GM; Hallupp, M; Huang, Y; Kim, WS; Kwok, JB; Mather, K; Mellick, GD; Sachdev, PS; Silburn, PA1
Fukushima, T; Hayakawa, T; Hidaka, T; Kakamu, T; Kanda, H; Kumagai, T; Luo, Y; Mori, Y; Song, J; Tan, X; Tsuji, M; Wang, P1
Ali, J; Baboota, S; Mustafa, G; Pangeni, R; Sharma, S1
Auinger, P; Cain, KC; Cholerton, B; Ginghina, C; Liu, C; Shi, M; Zhang, J1
Hanaki, T; Horikoshi, Y; Kitagawa, Y; Koike, T; Matsura, T; Nakaso, K; Nakasone, M; Takahashi, T1
Ali, J; Baboota, S; Narang, JK; Sharma, S1
Ascherio, A; Gao, X; Hughes, KC; Kim, IY; Rimm, EB; Schwarzschild, MA; Wang, M; Weisskopf, MG1
Abbasi, M; Kord Valeshabad, A; Mehrannia, K; Omidi, N; Pasbakhsh, P; Ragerdi Kashani, I; Sobhani, AG1
Chen, CM; Chen, YC; Cheng, HS; Cheng, ML; Chiu, DT; Liu, JL; Wu, YR1
Lim, TM; Zhou, ZD1
Bravo-San Pedro, JM; Cuadrado, A; Fuentes, JM; Gómez-Sánchez, R; González-Polo, RA; Lastres-Becker, I; Morán, JM; Niso-Santano, M; Ortiz-Ortiz, MA; Soler, G1
Deuel, L; Dorsey, ER; Ravina, B; Siderowf, A1
Hauser, RA1
Fukushima, W; Fukuyama, H; Hirota, Y; Kawamura, N; Kiyohara, C; Miki, T; Miyake, Y; Nagai, M; Oeda, T; Sakae, N; Sasaki, S; Tanaka, K; Tsuboi, Y; Yamada, T1
Albarracin, SL; Barreto, GE; Casas, Z; Gonzalez, J; Morales, L; Samudio, I; Stab, BR; Sutachan, JJ1
Butterfield, DA; Calabrese, V; Castegna, A; Drake, J; Scapagnini, G1
Bonnefoy, M; Drai, J; Kostka, T1
Ascherio, A; Chen, H; Hernán, MA; Spiegelman, D; Willett, WC; Zhang, SM1
Olanow, CW2
Horstink, MW; van Engelen, BG1
Hunter, DA1
Anagnostouli, M; Kapaki, E; Papageorgiou, C; Paraskevas, GP; Petropoulou, O; Vagenas, V1
Flint Beal, M; Fontaine, D; Shults, CW; Song, D1
Ichikawa, Y; Igarashi, O; Ikeda, K; Iwasaki, Y; Kawabe, K1
Jankovic, J; Olanow, CW1
Etminan, M; Gill, SS; Samii, A1
Pham, DQ; Plakogiannis, R1
Bodmer, R; Liu, J; Neckameyer, WS; Oldham, S; Qian, L; Wang, D; Wang, J; Xia, K; Xiong, H; Zhang, Z1
Bier, E1
Bonham, CC; Davisson, VJ; Hindupur, J; Liu, F; Nguyen, JL; Rochet, JC; Ruf, KJ; Schieler, JL; Wood, KV; Zhu, J1
Gerlach, M; Riederer, P; Youdim, MB1
Abe, T; Hamato, F; Saheki, M; Sasaki, K; Takahashi, S; Tohgi, H1
Carter, J; Fahn, S; Gauthier, S; Goetz, CG; Golbe, LI; Jankovic, J; Koller, W; Lang, AE; McDermott, MP; Olanow, CW1
LeWitt, PA3
Brady, J; Carter, J; Como, P; Growdon, J; Huber, S; Kanigan, B; Kieburtz, K; Landow, E; McDermott, M; Rudolph, A1
Ward, J1
Calne, DB; Uitti, RJ; Vingerhoets, FJ1
Jackson-Lewis, V; Muthane, U; Przedborski, S1
Tangney, CC; Tanner, CM1
Nakashima, K; Takahashi, K1
Cabrera-Valdivia, F; Fernández-Calle, P; Jiménez-Jiménez, FJ; Molina, JA1
Ahlskog, JE; Kokmen, E; Low, PA; Nickander, KK; Petersen, RC; Tyce, GM; Uitti, RJ1
Cote, L; Logroscino, G; Marder, K; Mayeux, R; Shea, S; Tang, MX1
Grandinetti, A; Morens, DM; Park, CB; Ross, GW; Waslien, CI; White, LR1
Battisti, C; Dotti, MT; Federico, A; Formichi, P1
Carvey, PM; Goetz, CG; Ling, ZD; Lipton, JW; Pappert, EJ; Stebbins, GT; Tangney, CC1
Heinonen, E; Mäki-Ikola, O1
Cui, L; LeWitt, P; Oakes, D1
Hershey, LA; Holmlund, T; Marshall, JR; Scheider, WL; Vena, JE1
Jiménez-Jiménez, FJ; Molina, JA1
Arenas, J; Benito-León, J; de Bustos, F; Enríquez-de-Salamanca, R; Gasalla, T; Jiménez-Jiménez, FJ; Molina, JA; Navarro, JA; Ortí-Pareja, M; Tallón-Barranco, A1
Arencibia, R; Broche, F; Castellano, O; Céspedes, EM; García, JC; Gómez, AA; González-Fraguela, ME1
Fahn, S; Kuskowski, MA; Vatassery, GT1
Selley, ML1
Vatassery, GT2
Koller, WC1
Shoulson, I5
Bauer, T; Dysken, M; Vatassery, GT1
Blackburn, G1
Joseph, JA; Youdim, KA1
Fahn, S; Giladi, N; Jankovic, J; McDermott, MP; Przedborski, S; Stern, M; Tanner, C1
Hirai, S; Sotomatsu, A; Tanaka, M1
Berg, MJ; Collier, DS; Fincham, RW1
Nag, D1
King, D; Playfer, JR; Roberts, NB1
Daniel, SE; Dexter, DT; Jenner, P; Lees, AJ; Marsden, CD; Peters, TJ; Ward, RJ; Wells, FR1
Levivier, M; Przedborski, S1
Fahn, S3
Codoceo, R; Domingo, J; Férnandez-Calle, P; García-Ruiz, PJ; Jiménez-Jiménez, FJ; Molina, JA; Pondal, M; Urra, DG; Vázquez, A1
Adams, JD; Klaidman, LK; Miller, CA; Odunze, IN; Shen, HC1
Adams, JD; Odunze, IN1
Cotton, P1
Landau, WM1
Heikkila, RE; Sieber, BA; Terleckyj, I1
Factor, SA; Sanchez-Ramos, JR; Weiner, WJ1
Friedman, JH1
Stern, GM1
Cadet, JL1
Lewin, R1
Merz, B1
Grimes, JD; Hassan, MN; Thakar, JH1
Hirai, S1
Grimes, JD; Hassan, MN; Thakar, J1
Nagay, B1

Reviews

35 review(s) available for d-alpha tocopherol and Idiopathic Parkinson Disease

ArticleYear
Vitamin E therapy in Parkinson's disease.
    Toxicology, 2003, Jul-15, Volume: 189, Issue:1-2

    Topics: alpha-Tocopherol; Animals; Antioxidants; Dietary Supplements; Humans; Mitochondria; Oxidative Stress; Parkinson Disease

2003
Dietary Antioxidants and Risk of Parkinson's Disease: A Systematic Review and Dose-Response Meta-analysis of Observational Studies.
    Advances in nutrition (Bethesda, Md.), 2022, 10-02, Volume: 13, Issue:5

    Topics: Anthocyanins; Antioxidants; Ascorbic Acid; beta Carotene; Humans; Lutein; Observational Studies as Topic; Parkinson Disease; Prospective Studies; Risk Factors; Vitamin E; Zinc

2022
An umbrella review of systematic reviews with meta-analysis on the role of vitamins in Parkinson's disease.
    Acta neurologica Belgica, 2023, Volume: 123, Issue:1

    Topics: Humans; Parkinson Disease; Systematic Reviews as Topic; Vitamin A; Vitamin B 12; Vitamin D; Vitamin E; Vitamin K; Vitamins

2023
Effects of vitamin E on neurodegenerative diseases: an update.
    Acta neurobiologiae experimentalis, 2021, Volume: 81, Issue:1

    Topics: Alzheimer Disease; Amyotrophic Lateral Sclerosis; Animals; Humans; Neurodegenerative Diseases; Parkinson Disease; Stroke; Vitamin E

2021
Effect of dietary vitamins C and E on the risk of Parkinson's disease: A meta-analysis.
    Clinical nutrition (Edinburgh, Scotland), 2021, Volume: 40, Issue:6

    Topics: Ascorbic Acid; Dietary Supplements; Humans; Parkinson Disease; Risk Factors; Vitamin E

2021
Early pharmacologic treatment in Parkinson's disease.
    The American journal of managed care, 2010, Volume: 16 Suppl Implications

    Topics: Antiparkinson Agents; Disease Progression; Dopamine Agonists; Early Diagnosis; Humans; Levodopa; Monoamine Oxidase Inhibitors; Parkinson Disease; Ubiquinone; Vitamin E

2010
Cellular and molecular mechanisms of antioxidants in Parkinson's disease.
    Nutritional neuroscience, 2012, Volume: 15, Issue:3

    Topics: alpha-Synuclein; Animals; Antioxidants; Ascorbic Acid; Carrier Proteins; Cell Death; Dopamine; Dopaminergic Neurons; Humans; Inflammation; Nerve Tissue Proteins; Oxidation-Reduction; Oxidative Stress; Parkinson Disease; Polyphenols; Reactive Oxygen Species; Signal Transduction; Substantia Nigra; Ubiquinone; Vitamin A; Vitamin E

2012
Vitamin E and neurodegenerative disorders associated with oxidative stress.
    Nutritional neuroscience, 2002, Volume: 5, Issue:4

    Topics: Alzheimer Disease; Amyotrophic Lateral Sclerosis; Biological Availability; Dyskinesias; Humans; Huntington Disease; Intestinal Absorption; Lipid Peroxidation; Multiple Sclerosis; Neurodegenerative Diseases; Oxidative Stress; Parkinson Disease; Vitamin E

2002
[Antioxidants to slow aging, facts and perspectives].
    Presse medicale (Paris, France : 1983), 2002, Jul-27, Volume: 31, Issue:25

    Topics: Aging; Alzheimer Disease; Animals; Antioxidants; Arteriosclerosis; Ascorbic Acid; Carotenoids; Cataract; Chronic Disease; Disease Models, Animal; Evidence-Based Medicine; Free Radicals; Humans; Lutein; Macular Degeneration; Neoplasms; Oxidative Stress; Parkinson Disease; Reactive Oxygen Species; Vitamin E

2002
Neuroprotective therapy in Parkinson's disease and motor complications: a search for a pathogenesis-targeted, disease-modifying strategy.
    Movement disorders : official journal of the Movement Disorder Society, 2005, Volume: 20 Suppl 11

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antiparkinson Agents; Coenzymes; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Humans; Indans; Levodopa; Membrane Proteins; N-Methylaspartate; Neuroprotective Agents; Parkinson Disease; Prostaglandin-Endoperoxide Synthases; Ubiquinone; Vitamin E

2005
Intake of vitamin E, vitamin C, and carotenoids and the risk of Parkinson's disease: a meta-analysis.
    The Lancet. Neurology, 2005, Volume: 4, Issue:6

    Topics: Ascorbic Acid; beta Carotene; Carotenoids; Humans; Parkinson Disease; Risk Factors; Vitamin E

2005
Vitamin E supplementation in Alzheimer's disease, Parkinson's disease, tardive dyskinesia, and cataract: Part 2.
    The Annals of pharmacotherapy, 2005, Volume: 39, Issue:12

    Topics: Alzheimer Disease; Antioxidants; Cataract; Clinical Trials as Topic; Dyskinesia, Drug-Induced; Humans; Parkinson Disease; Randomized Controlled Trials as Topic; Vitamin E

2005
Neuroprotective therapeutic strategies. Comparison of experimental and clinical results.
    Biochemical pharmacology, 1995, Jun-29, Volume: 50, Issue:1

    Topics: Animals; Humans; Nervous System Diseases; Parkinson Disease; Selegiline; Vitamin E

1995
Clinical trials of neuroprotection in Parkinson's disease: long-term selegiline and alpha-tocopherol treatment.
    Journal of neural transmission. Supplementum, 1994, Volume: 43

    Topics: Clinical Trials as Topic; Humans; Neuroprotective Agents; Parkinson Disease; Selegiline; Time Factors; Vitamin E

1994
Free radicals, antioxidants and preventive geriatrics.
    Australian family physician, 1994, Volume: 23, Issue:7

    Topics: Aged; Aging; Animals; Antioxidants; Arteriosclerosis; Ascorbic Acid; Cataract; Diet; Free Radicals; Humans; Parkinson Disease; Reactive Oxygen Species; Reperfusion Injury; Vitamin A; Vitamin E

1994
Neuroprotection by anti-oxidant strategies in Parkinson's disease.
    European neurology, 1993, Volume: 33 Suppl 1

    Topics: Antioxidants; Corpus Striatum; Dopamine; Humans; Monoamine Oxidase; Parkinson Disease; Reactive Oxygen Species; Receptors, Dopamine; Selegiline; Substantia Nigra; Vitamin E

1993
[Fat-soluble vitamin therapy in senile dementia and Parkinson's disease].
    Nihon rinsho. Japanese journal of clinical medicine, 1993, Volume: 51, Issue:4

    Topics: Aged; Alzheimer Disease; Free Radicals; Humans; Parkinson Disease; Vitamin E

1993
[Pathogenesis of Parkinson's disease: a possibility of oxidation].
    Neurologia (Barcelona, Spain), 1993, Volume: 8, Issue:4

    Topics: Ascorbic Acid; Catalase; Central Nervous System Diseases; Dopamine; Female; Free Radicals; Humans; Male; Oxidants; Parkinson Disease; Superoxide Dismutase; Vitamin E

1993
[Neuroprotective and neurorestorative therapy in Parkinson's disease].
    Revista de neurologia, 1997, Volume: 25 Suppl 2

    Topics: Antiparkinson Agents; Apoptosis; Brain Tissue Transplantation; Chelation Therapy; Corpus Striatum; Dopamine; Erythrocytes; Free Radicals; Gangliosides; Genetic Therapy; Glutathione Peroxidase; Humans; Levodopa; Monoamine Oxidase Inhibitors; Neurons; Oxidative Stress; Parkinson Disease; Selegiline; Selenium; Vitamin E

1997
Vitamin E and other endogenous antioxidants in the central nervous system.
    Geriatrics, 1998, Volume: 53 Suppl 1

    Topics: Alzheimer Disease; Antioxidants; Central Nervous System; Dyskinesia, Drug-Induced; Humans; Neurodegenerative Diseases; Oxidative Stress; Parkinson Disease; Vitamin E

1998
Neuroprotection for Parkinson's disease.
    Annals of neurology, 1998, Volume: 44, Issue:3 Suppl 1

    Topics: Antiparkinson Agents; Clinical Trials as Topic; Dopamine Agents; Humans; Levodopa; Neuroprotective Agents; Parkinson Disease; Selegiline; Vitamin E

1998
DATATOP: a decade of neuroprotective inquiry. Parkinson Study Group. Deprenyl And Tocopherol Antioxidative Therapy Of Parkinsonism.
    Annals of neurology, 1998, Volume: 44, Issue:3 Suppl 1

    Topics: Antioxidants; Antiparkinson Agents; Clinical Trials as Topic; Disease Progression; Humans; Neuroprotective Agents; Parkinson Disease; Selegiline; Vitamin E

1998
High doses of vitamin E in the treatment of disorders of the central nervous system in the aged.
    The American journal of clinical nutrition, 1999, Volume: 70, Issue:5

    Topics: Aged; Alzheimer Disease; Antioxidants; Central Nervous System Diseases; Dose-Response Relationship, Drug; Geriatrics; Humans; Oxidative Stress; Parkinson Disease; Vitamin E

1999
A possible emerging role of phytochemicals in improving age-related neurological dysfunctions: a multiplicity of effects.
    Free radical biology & medicine, 2001, Mar-15, Volume: 30, Issue:6

    Topics: Alzheimer Disease; Animals; Ascorbic Acid; Capsicum; Carotenoids; Flavonoids; Fruit; Garlic; Ginkgo biloba; Humans; Nervous System Diseases; Panax; Parkinson Disease; Phenols; Phytotherapy; Plants, Medicinal; Polymers; Polyphenols; Tea; Vitamin E

2001
Parkinsonism treatment: Part III--Update.
    The Annals of pharmacotherapy, 1992, Volume: 26, Issue:2

    Topics: Antioxidants; Dopamine Agents; Female; Fetal Tissue Transplantation; Humans; Male; Middle Aged; Parasympatholytics; Parkinson Disease; Pergolide; Selegiline; Vitamin E

1992
Vitamin E. Neurochemistry and implications for neurodegeneration in Parkinson's disease.
    Annals of the New York Academy of Sciences, 1992, Sep-30, Volume: 669

    Topics: Animals; Brain; Humans; Nerve Degeneration; Nervous System Diseases; Organ Specificity; Parkinson Disease; Vitamin E; Vitamin E Deficiency

1992
[Current therapeutic approach in Parkinson disease].
    Revue medicale de Bruxelles, 1992, Volume: 13, Issue:10

    Topics: Antiparkinson Agents; Apomorphine; Bromocriptine; Fetal Tissue Transplantation; Humans; Levodopa; Mesencephalon; Parkinson Disease; Selegiline; Vitamin E

1992
Neuroprotective clinical strategies for Parkinson's disease.
    Annals of neurology, 1992, Volume: 32 Suppl

    Topics: Drug Therapy, Combination; Humans; Iron; Oxidation-Reduction; Parkinson Disease; Selegiline; Vitamin E

1992
Antioxidative therapeutic strategies for Parkinson's disease.
    Annals of the New York Academy of Sciences, 1992, May-11, Volume: 648

    Topics: Antioxidants; Double-Blind Method; Free Radical Scavengers; Humans; Parkinson Disease; Selegiline; Vitamin E

1992
Biochemical mechanisms of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity. Could oxidative stress be involved in the brain?
    Biochemical pharmacology, 1991, Apr-15, Volume: 41, Issue:8

    Topics: Animals; Brain; Corpus Striatum; Dopamine; Free Radicals; Glutathione; Hydrogen Peroxide; Lipid Peroxides; Liver; Mesencephalon; Mitochondria; MPTP Poisoning; Oxidation-Reduction; Parkinson Disease; Vitamin E

1991
Parkinson's disease update.
    Rhode Island medical journal, 1989, Volume: 72, Issue:11

    Topics: Adrenal Medulla; Clinical Trials as Topic; Humans; Parkinson Disease; Selegiline; Vitamin E

1989
The endogenous toxin hypothesis of the etiology of Parkinson's disease and a pilot trial of high-dosage antioxidants in an attempt to slow the progression of the illness.
    Annals of the New York Academy of Sciences, 1989, Volume: 570

    Topics: Adult; Aged; Aging; Antioxidants; Ascorbic Acid; Cell Count; Female; Free Radicals; Humans; Male; Middle Aged; Neurons; Parkinson Disease; Vitamin E

1989
Prevention of progression of Parkinson's disease with antioxidative therapy.
    Progress in neuro-psychopharmacology & biological psychiatry, 1988, Volume: 12, Issue:2-3

    Topics: Antioxidants; Humans; Parkinson Disease; Selegiline; Vitamin E

1988
Antioxidant therapy in Parkinson's disease.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 1987, Volume: 14, Issue:3 Suppl

    Topics: Aging; Antioxidants; Humans; Melanins; Monoamine Oxidase; Neurotoxins; Parkinson Disease; Smoking; Vitamin E

1987
[Dupuytren's contracture].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1970, Nov-15, Volume: 23, Issue:22

    Topics: Age Factors; Aged; Alcoholism; Autoantibodies; Chronic Disease; Dupuytren Contracture; Epilepsy; Female; Humans; Male; Middle Aged; Parkinson Disease; Postoperative Complications; Prognosis; Sex Factors; Vitamin E

1970

Trials

30 trial(s) available for d-alpha tocopherol and Idiopathic Parkinson Disease

ArticleYear
Analysis of a precision medicine approach to treating Parkinson's disease: Analysis of the DATATOP study.
    Parkinsonism & related disorders, 2022, Volume: 94

    Topics: alpha-Tocopherol; Antiparkinson Agents; Humans; Parkinson Disease; Precision Medicine; Proteomics; Selegiline

2022
Vitamin B12 and Homocysteine Levels Predict Different Outcomes in Early Parkinson's Disease.
    Movement disorders : official journal of the Movement Disorder Society, 2018, Volume: 33, Issue:5

    Topics: alpha-Tocopherol; Antioxidants; Antiparkinson Agents; Cognition Disorders; Double-Blind Method; Female; Follow-Up Studies; Homocysteine; Humans; Male; Mental Status Schedule; Middle Aged; Parkinson Disease; Predictive Value of Tests; Selegiline; Treatment Outcome; Vitamin B 12

2018
Cerebrospinal fluid α-synuclein predicts cognitive decline in Parkinson disease progression in the DATATOP cohort.
    The American journal of pathology, 2014, Volume: 184, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; alpha-Synuclein; alpha-Tocopherol; Antiparkinson Agents; Cognition Disorders; Cohort Studies; Disease Progression; Double-Blind Method; Female; Humans; Male; Middle Aged; Neuropsychological Tests; Parkinson Disease; Selegiline

2014
The effects of omega-3 fatty acids and vitamin E co-supplementation on clinical and metabolic status in patients with Parkinson's disease: A randomized, double-blind, placebo-controlled trial.
    Neurochemistry international, 2017, Volume: 108

    Topics: Aged; Aged, 80 and over; Dietary Supplements; Double-Blind Method; Fatty Acids, Omega-3; Female; Humans; Linseed Oil; Male; Middle Aged; Parkinson Disease; Vitamin E

2017
The effects of omega-3 fatty acids and vitamin E co-supplementation on gene expression related to inflammation, insulin and lipid in patients with Parkinson's disease: A randomized, double-blind, placebo-controlled trial.
    Clinical neurology and neurosurgery, 2019, Volume: 176

    Topics: Adult; Double-Blind Method; Fatty Acids, Omega-3; Female; Gene Expression; Humans; Inflammation; Leukocytes, Mononuclear; Lipids; Male; Middle Aged; Parkinson Disease; Tumor Necrosis Factor-alpha; Vitamin E

2019
CSF tau and tau/Aβ42 predict cognitive decline in Parkinson's disease.
    Parkinsonism & related disorders, 2015, Volume: 21, Issue:3

    Topics: Adult; Aged; Amyloid beta-Peptides; Antioxidants; Apolipoproteins E; Cognition Disorders; Cohort Studies; Cross-Sectional Studies; Female; Humans; Linear Models; Male; Middle Aged; Monoamine Oxidase Inhibitors; Neuropsychological Tests; Parkinson Disease; Peptide Fragments; Predictive Value of Tests; Selegiline; Severity of Illness Index; tau Proteins; Time Factors; Vitamin E

2015
Pilot trial of high dosages of coenzyme Q10 in patients with Parkinson's disease.
    Experimental neurology, 2004, Volume: 188, Issue:2

    Topics: Calcium; Coenzymes; Cognition; Dose-Response Relationship, Drug; Drug Therapy, Combination; Dyspepsia; Female; Humans; Male; Middle Aged; Motor Activity; Parkinson Disease; Pilot Projects; Safety; Time Factors; Ubiquinone; Vitamin E

2004
Factors predictive of the need for levodopa therapy in early, untreated Parkinson's disease. The Parkinson Study Group.
    Archives of neurology, 1995, Volume: 52, Issue:6

    Topics: Adult; Age Factors; Aged; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Levodopa; Male; Middle Aged; Neuropsychological Tests; Parkinson Disease; Prospective Studies; Risk Factors; Selegiline; Sex Factors; Vitamin E

1995
Cerebrospinal fluid homovanillic acid in the DATATOP study on Parkinson's disease. Parkinson Study Group.
    Archives of neurology, 1995, Volume: 52, Issue:3

    Topics: Adult; Aged; Drug Therapy, Combination; Female; Homovanillic Acid; Humans; Male; Middle Aged; Parkinson Disease; Placebos; Selegiline; Vitamin E

1995
The effect of deprenyl and tocopherol on cognitive performance in early untreated Parkinson's disease. Parkinson Study Group.
    Neurology, 1994, Volume: 44, Issue:9

    Topics: Aged; Cognition Disorders; Female; Humans; Male; Middle Aged; Parkinson Disease; Selegiline; Vitamin E

1994
Effects of tocopherol and deprenyl on the progression of disability in early Parkinson's disease.
    The New England journal of medicine, 1993, Jan-21, Volume: 328, Issue:3

    Topics: Activities of Daily Living; Arrhythmias, Cardiac; Follow-Up Studies; Humans; Parkinson Disease; Psychiatric Status Rating Scales; Psychomotor Performance; Regression Analysis; Selegiline; Vitamin E

1993
Vitamin E and PD.
    Neurology, 1993, Volume: 43, Issue:3 Pt 1

    Topics: Humans; Parkinson Disease; Vitamin E

1993
The need for levodopa as an end point of Parkinson's disease progression in a clinical trial of selegiline and alpha-tocopherol. Parkinson Study Group.
    Movement disorders : official journal of the Movement Disorder Society, 1997, Volume: 12, Issue:2

    Topics: Activities of Daily Living; Adult; Aged; Antioxidants; Antiparkinson Agents; Disability Evaluation; Drug Therapy, Combination; Female; Humans; Levodopa; Male; Middle Aged; Neurologic Examination; Parkinson Disease; Selegiline; Treatment Outcome; Vitamin E

1997
Cerebrospinal fluid levels of alpha-tocopherol (vitamin E) in Parkinson's disease.
    Journal of neural transmission (Vienna, Austria : 1996), 1997, Volume: 104, Issue:11-12

    Topics: Aged; Antiparkinson Agents; Chromatography, High Pressure Liquid; Female; Humans; Male; Middle Aged; Parkinson Disease; Reference Values; Vitamin E

1997
Mortality in DATATOP: a multicenter trial in early Parkinson's disease. Parkinson Study Group.
    Annals of neurology, 1998, Volume: 43, Issue:3

    Topics: Aged; Antiparkinson Agents; Cause of Death; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Parkinson Disease; Selegiline; Vitamin E

1998
[Indicators of oxidative stress and the effect of antioxidant treatment in patients with primary Parkinson disease].
    Revista de neurologia, 1998, Volume: 26, Issue:149

    Topics: Antioxidants; Ascorbic Acid; Biomarkers; Catalase; Disease Progression; Humans; Malondialdehyde; Monoamine Oxidase Inhibitors; Oxidative Stress; Parkinson Disease; Phospholipases A; Phospholipases A2; Reactive Oxygen Species; Spectrophotometry; Vitamin E

1998
Alpha tocopherol in CSF of subjects taking high-dose vitamin E in the DATATOP study. Parkinson Study Group.
    Neurology, 1998, Volume: 50, Issue:6

    Topics: Antioxidants; Antiparkinson Agents; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Parkinson Disease; Selegiline; Vitamin E

1998
DATATOP: a decade of neuroprotective inquiry. Parkinson Study Group. Deprenyl And Tocopherol Antioxidative Therapy Of Parkinsonism.
    Annals of neurology, 1998, Volume: 44, Issue:3 Suppl 1

    Topics: Antioxidants; Antiparkinson Agents; Clinical Trials as Topic; Disease Progression; Humans; Neuroprotective Agents; Parkinson Disease; Selegiline; Vitamin E

1998
Freezing of gait in PD: prospective assessment in the DATATOP cohort.
    Neurology, 2001, Jun-26, Volume: 56, Issue:12

    Topics: Aged; Double-Blind Method; Female; Gait; Humans; Male; Middle Aged; Parkinson Disease; Prospective Studies; Selegiline; Vitamin E

2001
An interim report of the effect of selegiline (L-deprenyl) on the progression of disability in early Parkinson's disease. The Parkinson Study Group.
    European neurology, 1992, Volume: 32 Suppl 1

    Topics: Activities of Daily Living; Adult; Aged; Disability Evaluation; Double-Blind Method; Female; Follow-Up Studies; Humans; Long-Term Care; Male; Middle Aged; Neurologic Examination; Parkinson Disease; Selegiline; Vitamin E

1992
Antioxidative therapeutic strategies for Parkinson's disease.
    Annals of the New York Academy of Sciences, 1992, May-11, Volume: 648

    Topics: Antioxidants; Double-Blind Method; Free Radical Scavengers; Humans; Parkinson Disease; Selegiline; Vitamin E

1992
Deprenyl's effect at slowing progression of parkinsonian disability: the DATATOP study. The Parkinson Study Group.
    Acta neurologica Scandinavica. Supplementum, 1991, Volume: 136

    Topics: Adult; Aged; Brain; Disability Evaluation; Drug Therapy, Combination; Humans; Middle Aged; Monoamine Oxidase; Neurologic Examination; Parkinson Disease; Selegiline; Vitamin E

1991
An open trial of high-dosage antioxidants in early Parkinson's disease.
    The American journal of clinical nutrition, 1991, Volume: 53, Issue:1 Suppl

    Topics: Adult; Aged; Ascorbic Acid; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Pilot Projects; Vitamin E

1991
Vitamin E therapy in Parkinson's disease.
    Advances in neurology, 1990, Volume: 53

    Topics: Aged; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Levodopa; Male; Middle Aged; Neurologic Examination; Parkinson Disease; Retrospective Studies; Vitamin E

1990
DATATOP: a multicenter controlled clinical trial in early Parkinson's disease. Parkinson Study Group.
    Archives of neurology, 1989, Volume: 46, Issue:10

    Topics: Cohort Studies; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Multicenter Studies as Topic; Parkinson Disease; Phenethylamines; Randomized Controlled Trials as Topic; Selegiline; Vitamin E

1989
Effect of deprenyl on the progression of disability in early Parkinson's disease.
    The New England journal of medicine, 1989, 11-16, Volume: 321, Issue:20

    Topics: Activities of Daily Living; Clinical Trials as Topic; Drug Therapy, Combination; Employment; Female; Follow-Up Studies; Humans; Levodopa; Male; Middle Aged; Multicenter Studies as Topic; Parkinson Disease; Phenethylamines; Random Allocation; Selegiline; Vitamin E

1989
Parkinson's disease update.
    Rhode Island medical journal, 1989, Volume: 72, Issue:11

    Topics: Adrenal Medulla; Clinical Trials as Topic; Humans; Parkinson Disease; Selegiline; Vitamin E

1989
Deprenyl and tocopherol antioxidative therapy of parkinsonism (DATATOP). Parkinson Study Group.
    Acta neurologica Scandinavica. Supplementum, 1989, Volume: 126

    Topics: Adult; Aged; Antioxidants; Canada; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Multicenter Studies as Topic; Parkinson Disease; Phenethylamines; Randomized Controlled Trials as Topic; Selegiline; United States; Vitamin E

1989
Drug trial for Parkinson's.
    Science (New York, N.Y.), 1987, Jun-12, Volume: 236, Issue:4807

    Topics: Clinical Trials as Topic; Humans; Parkinson Disease; Phenethylamines; Selegiline; Vitamin E

1987
Adrenal-to-brain transplants continue as neurologists test two new drugs.
    JAMA, 1987, Aug-21, Volume: 258, Issue:7

    Topics: Adrenal Glands; Caudate Nucleus; Clinical Trials as Topic; Humans; Parkinson Disease; Phenethylamines; Selegiline; Vitamin E

1987

Other Studies

59 other study(ies) available for d-alpha tocopherol and Idiopathic Parkinson Disease

ArticleYear
A pharmacological analysis elucidating why, in contrast to (-)-deprenyl (selegiline), alpha-tocopherol was ineffective in the DATATOP study.
    Life sciences, 2003, Apr-25, Volume: 72, Issue:23

    Topics: alpha-Tocopherol; Animals; Benzofurans; Brain; Dopamine; In Vitro Techniques; Male; Monoamine Oxidase Inhibitors; Norepinephrine; Parkinson Disease; Rats; Rats, Wistar; Selegiline; Treatment Failure

2003
Plasma and CSF markers of oxidative stress are increased in Parkinson's disease and influenced by antiparkinsonian medication.
    Neurobiology of disease, 2004, Volume: 15, Issue:1

    Topics: Adult; alpha-Tocopherol; Antioxidants; Antiparkinson Agents; Ascorbic Acid; Biomarkers; Brain; Dopamine; Female; Humans; Levodopa; Lipoproteins; Male; Middle Aged; Oxidative Stress; Parkinson Disease; Reference Values; Sulfhydryl Compounds; Ubiquinone; Up-Regulation

2004
Comment on "effect of dietary vitamins C and E on the risk of Parkinson's disease: A meta-analysis".
    Clinical nutrition (Edinburgh, Scotland), 2022, Volume: 41, Issue:1

    Topics: Ascorbic Acid; Diet; Humans; Parkinson Disease; Vitamin E; Vitamins

2022
Evaluating the neuroprotective activities of vinpocetine, punicalagin, niacin and vitamin E against behavioural and motor disabilities of manganese-induced Parkinson's disease in Sprague Dawley rats.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 153

    Topics: Acetylcholinesterase; Animals; Anti-Inflammatory Agents; Antioxidants; Glycogen Synthase Kinase 3 beta; Hydrolyzable Tannins; Manganese; Neuroprotection; Neuroprotective Agents; Niacin; Oxidative Stress; Parkinson Disease; Rats; Rats, Sprague-Dawley; Vinca Alkaloids; Vitamin E

2022
Dietary β-carotene and vitamin A and risk of Parkinson disease: A protocol for systematic review and meta-analysis.
    Medicine, 2022, Oct-14, Volume: 101, Issue:41

    Topics: Ascorbic Acid; beta Carotene; Cross-Sectional Studies; Humans; Meta-Analysis as Topic; Parkinson Disease; Retrospective Studies; Risk Factors; Systematic Reviews as Topic; Vitamin A; Vitamin E

2022
Tocotrienol-Rich Fraction and Levodopa Regulate Proteins Involved in Parkinson's Disease-Associated Pathways in Differentiated Neuroblastoma Cells: Insights from Quantitative Proteomic Analysis.
    Nutrients, 2022, Nov-03, Volume: 14, Issue:21

    Topics: Chromatography, Liquid; Humans; Levodopa; Neuroblastoma; Parkinson Disease; Proteomics; Tandem Mass Spectrometry; Tocotrienols; Vitamin E

2022
Vitamin E Analog Trolox Attenuates MPTP-Induced Parkinson's Disease in Mice, Mitigating Oxidative Stress, Neuroinflammation, and Motor Impairment.
    International journal of molecular sciences, 2023, Jun-09, Volume: 24, Issue:12

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Disease Models, Animal; Dopaminergic Neurons; Mice; Mice, Inbred C57BL; Motor Disorders; Neuroinflammatory Diseases; Neuroprotective Agents; Oxidative Stress; Parkinson Disease; Substantia Nigra; Tyrosine 3-Monooxygenase; Vitamin E

2023
Protective Effect of Tocotrienol on In Vitro and In Vivo Models of Parkinson's Disease.
    Journal of nutritional science and vitaminology, 2019, Volume: 65, Issue:Supplement

    Topics: Animals; Cytoprotection; Disease Models, Animal; Humans; Mice; Neuroprotective Agents; Oxidative Stress; Parkinson Disease; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; Tocotrienols; Vitamin E

2019
Dietary Antioxidants and Risk of Parkinson's Disease in the Singapore Chinese Health Study.
    Movement disorders : official journal of the Movement Disorder Society, 2020, Volume: 35, Issue:10

    Topics: Aged; Antioxidants; China; Diet; Female; Humans; Male; Middle Aged; Parkinson Disease; Prospective Studies; Risk Factors; Singapore; Vitamin E

2020
Dietary Antioxidants and the Risk of Parkinson Disease: The Swedish National March Cohort.
    Neurology, 2021, 02-09, Volume: 96, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antioxidants; Ascorbic Acid; beta Carotene; Female; Follow-Up Studies; Food; Humans; Incidence; Male; Middle Aged; Parkinson Disease; Registries; Sweden; Vitamin E; Young Adult

2021
Dietary antioxidants and risk of Parkinson's disease in two population-based cohorts.
    Movement disorders : official journal of the Movement Disorder Society, 2017, Volume: 32, Issue:11

    Topics: Aged; Antioxidants; Ascorbic Acid; beta Carotene; Diet; Female; Follow-Up Studies; Humans; Male; Middle Aged; Neuroprotective Agents; Parkinson Disease; Sex Factors; Sweden; Vitamin E

2017
Vitamin E Loaded Naringenin Nanoemulsion via Intranasal Delivery for the Management of Oxidative Stress in a 6-OHDA Parkinson's Disease Model.
    BioMed research international, 2019, Volume: 2019

    Topics: Administration, Intranasal; Animals; Antioxidants; Behavior, Animal; Emulsions; Female; Flavanones; Levodopa; Male; Nanoparticles; Oxidative Stress; Oxidopamine; Parkinson Disease; Particle Size; Rats; Rats, Wistar; Solubility; Viscosity; Vitamin E

2019
DNA methylation of the MAPT gene in Parkinson's disease cohorts and modulation by vitamin E in vitro.
    Movement disorders : official journal of the Movement Disorder Society, 2014, Volume: 29, Issue:13

    Topics: Adult; Aged; Aged, 80 and over; Antioxidants; Brain; Cell Line, Tumor; Cohort Studies; DNA Methylation; Female; Genotype; Humans; Leukocytes, Mononuclear; Male; Middle Aged; Neuroblastoma; Parkinson Disease; Promoter Regions, Genetic; tau Proteins; Transfection; Vitamin E

2014
Heavy metals in blood and urine and its relation to depressive symptoms in Parkinson's disease patients.
    Fukushima journal of medical science, 2013, Volume: 59, Issue:2

    Topics: Aged; Depression; Female; Humans; Male; Metals, Heavy; Middle Aged; Parkinson Disease; Vitamin B 12; Vitamin E

2013
Vitamin E loaded resveratrol nanoemulsion for brain targeting for the treatment of Parkinson's disease by reducing oxidative stress.
    Nanotechnology, 2014, Dec-05, Volume: 25, Issue:48

    Topics: Animals; Antioxidants; Biological Availability; Brain; Chemistry, Pharmaceutical; Emulsions; Female; Male; Nanoparticles; Oxidative Stress; Parkinson Disease; Particle Size; Polysorbates; Rats; Rats, Wistar; Resveratrol; Solubility; Stilbenes; Swine; Viscosity; Vitamin E

2014
Estrogen receptor-mediated effect of δ-tocotrienol prevents neurotoxicity and motor deficit in the MPTP mouse model of Parkinson's disease.
    Neuroscience letters, 2016, Jan-01, Volume: 610

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Male; Mice, Inbred C57BL; Motor Skills; Neuroprotective Agents; Parkinson Disease; Vitamin E

2016
Synergistic antioxidant action of vitamin E and rutin SNEDDS in ameliorating oxidative stress in a Parkinson's disease model.
    Nanotechnology, 2016, Sep-16, Volume: 27, Issue:37

    Topics: Biological Availability; Drug Delivery Systems; Emulsions; Humans; Nanoparticles; Oxidative Stress; Parkinson Disease; Particle Size; Rutin; Solubility; Surface-Active Agents; Vitamin E

2016
Intake of antioxidant vitamins and risk of Parkinson's disease.
    Movement disorders : official journal of the Movement Disorder Society, 2016, Volume: 31, Issue:12

    Topics: Adult; Aged; Antioxidants; Ascorbic Acid; Carotenoids; Female; Follow-Up Studies; Health Personnel; Humans; Male; Middle Aged; Nurses; Parkinson Disease; United States; Vitamin E

2016
The protective effect of vitamin E on locus coeruleus in early model of Parkinson's disease in rat: immunoreactivity evidence.
    Iranian biomedical journal, 2008, Volume: 12, Issue:4

    Topics: Animals; Disease Models, Animal; Immunohistochemistry; Locus Coeruleus; Male; Parkinson Disease; Rats; Rats, Sprague-Dawley; Tyrosine 3-Monooxygenase; Vesicular Monoamine Transport Proteins; Vitamin E

2008
Increased oxidative damage in peripheral blood correlates with severity of Parkinson's disease.
    Neurobiology of disease, 2009, Volume: 33, Issue:3

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Aged; Analysis of Variance; Blood Chemical Analysis; Chromatography, High Pressure Liquid; Deoxyguanosine; Erythrocytes; Female; Glutathione Peroxidase; Humans; Leukocytes; Logistic Models; Male; Malondialdehyde; Oxidative Stress; Parkinson Disease; Risk Factors; Vitamin E

2009
Dopamine (DA) induced irreversible proteasome inhibition via DA derived quinones.
    Free radical research, 2009, Volume: 43, Issue:4

    Topics: Animals; Arachidonic Acid; Catalase; Cell Line; Chymotrypsin; Dopamine; Glutathione; Humans; Hydrogen Peroxide; Indolequinones; Kinetics; Leupeptins; Mice; Oxidative Stress; Parkinson Disease; Protease Inhibitors; Proteasome Inhibitors; Superoxide Dismutase; Vitamin E

2009
Activation of apoptosis signal-regulating kinase 1 is a key factor in paraquat-induced cell death: modulation by the Nrf2/Trx axis.
    Free radical biology & medicine, 2010, May-15, Volume: 48, Issue:10

    Topics: Animals; Apoptosis; Cell Line; Fibroblasts; Humans; Intracellular Signaling Peptides and Proteins; Isothiocyanates; Kelch-Like ECH-Associated Protein 1; MAP Kinase Kinase 4; MAP Kinase Kinase Kinase 5; Mice; Mice, Knockout; Neuroblastoma; NF-E2-Related Factor 2; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Paraquat; Parkinson Disease; RNA, Small Interfering; Sulfoxides; Thiocyanates; Thioredoxins; Vitamin E

2010
Local institutional review board (IRB) review of a multicenter trial: local costs without local context.
    Annals of neurology, 2010, Volume: 67, Issue:2

    Topics: Antioxidants; Biomedical Research; Double-Blind Method; Ethics Committees, Research; Humans; Multicenter Studies as Topic; Parkinson Disease; Randomized Controlled Trials as Topic; Ubiquinone; United States; Vitamin E

2010
Dietary intake of antioxidant vitamins and risk of Parkinson's disease: a case-control study in Japan.
    European journal of neurology, 2011, Volume: 18, Issue:1

    Topics: Aged; Antioxidants; beta Carotene; Case-Control Studies; Diet; Diet Surveys; Female; Humans; Japan; Logistic Models; Male; Middle Aged; Odds Ratio; Parkinson Disease; Risk; Surveys and Questionnaires; Vegetables; Vitamin E

2011
Intakes of vitamins E and C, carotenoids, vitamin supplements, and PD risk.
    Neurology, 2002, Oct-22, Volume: 59, Issue:8

    Topics: Adult; Aged; Antioxidants; Ascorbic Acid; Carotenoids; Cohort Studies; Confidence Intervals; Female; Follow-Up Studies; Humans; Male; Middle Aged; Multivariate Analysis; Parkinson Disease; Prospective Studies; Risk Factors; Vitamin E

2002
Dietary vitamin E and Parkinson's disease: something to chew on.
    The Lancet. Neurology, 2003, Volume: 2, Issue:2

    Topics: Antioxidants; Cell Death; Diet; Epidemiologic Methods; Humans; Oxidative Stress; Parkinson Disease; Vitamin E

2003
The effect of coenzyme Q10 therapy in Parkinson disease could be symptomatic.
    Archives of neurology, 2003, Volume: 60, Issue:8

    Topics: Aged; Animals; Antioxidants; Coenzymes; Disease Progression; Dose-Response Relationship, Drug; Drug Interactions; Humans; Middle Aged; Parkinson Disease; Rats; Treatment Outcome; Ubiquinone; Vitamin E

2003
Coenzyme Q10 in early Parkinson disease.
    Archives of neurology, 2003, Volume: 60, Issue:8

    Topics: Animals; Antioxidants; Coenzymes; Drug Interactions; Humans; Parkinson Disease; Rats; Ubiquinone; Vitamin E

2003
Plasma levels of antioxidant vitamins C and E are decreased in vascular parkinsonism.
    Journal of the neurological sciences, 2003, Nov-15, Volume: 215, Issue:1-2

    Topics: Aged; Analysis of Variance; Antioxidants; Ascorbic Acid; Cerebrovascular Disorders; Female; Humans; Male; Middle Aged; Parkinson Disease; Statistics, Nonparametric; Vitamin E

2003
Vitamins A, C and E in vascular parkinsonism.
    Journal of the neurological sciences, 2004, Dec-15, Volume: 227, Issue:1

    Topics: Age Factors; Ascorbic Acid; Humans; Parkinson Disease; Vitamin A; Vitamin E

2004
Antioxidants protect PINK1-dependent dopaminergic neurons in Drosophila.
    Proceedings of the National Academy of Sciences of the United States of America, 2006, Sep-05, Volume: 103, Issue:36

    Topics: Animals; Animals, Genetically Modified; Antioxidants; Cell Survival; DNA, Complementary; Drosophila; Drosophila Proteins; Gene Library; Gene Silencing; Humans; Mutation; Neurons; Oxidative Stress; Parkinson Disease; Protective Agents; Protein Kinases; RNA Interference; Superoxide Dismutase; Vitamin E

2006
Antioxidants put Parkinson flies back in the PINK.
    Proceedings of the National Academy of Sciences of the United States of America, 2006, Sep-05, Volume: 103, Issue:36

    Topics: Animals; Animals, Genetically Modified; Antioxidants; Drosophila; Drosophila Proteins; Gene Silencing; Humans; Mutation; Neurons; Oxidative Stress; Parkinson Disease; Protective Agents; Protein Kinases; Superoxide Dismutase; Vitamin E

2006
Methionine sulfoxide reductase A protects dopaminergic cells from Parkinson's disease-related insults.
    Free radical biology & medicine, 2008, Aug-01, Volume: 45, Issue:3

    Topics: Acetylcysteine; alpha-Synuclein; Animals; Antioxidants; Blotting, Western; Cell Death; Cells, Cultured; Cysteine Proteinase Inhibitors; Dopamine; Humans; Leupeptins; Mesencephalon; Methionine Sulfoxide Reductases; Mice; Neurons; Oxidation-Reduction; Oxidoreductases; Parkinson Disease; Rats; Rotenone; Uncoupling Agents; Vitamin E

2008
Reduced and oxidized forms of glutathione and alpha-tocopherol in the cerebrospinal fluid of parkinsonian patients: comparison between before and after L-dopa treatment.
    Neuroscience letters, 1995, Jan-16, Volume: 184, Issue:1

    Topics: Aged; Glutathione; Glutathione Disulfide; Humans; Levodopa; Middle Aged; Parkinson Disease; Vitamin E

1995
Deprenyl and the issue of neuroprotection.
    European neurology, 1994, Volume: 34, Issue:1

    Topics: Antioxidants; Cell Survival; Clinical Trials as Topic; Disability Evaluation; Drug Administration Schedule; Humans; Levodopa; Neurons; Parkinson Disease; Selegiline; Substantia Nigra; Vitamin E

1994
Alpha-tocopherol levels in parkinsonian brains.
    Annals of neurology, 1993, Volume: 33, Issue:5

    Topics: Brain; Brain Chemistry; Humans; Parkinson Disease; Reference Values; Substantia Nigra; Vitamin E; Vitamin E Deficiency

1993
No evidence for systemic oxidant stress in Parkinson's or Alzheimer's disease.
    Movement disorders : official journal of the Movement Disorder Society, 1995, Volume: 10, Issue:5

    Topics: Aged; Alzheimer Disease; Antiparkinson Agents; Brain; Cabergoline; Carbidopa; Diabetes Mellitus; Ergolines; Female; Free Radicals; Humans; Levodopa; Lipid Peroxidation; Male; Malondialdehyde; Oxidative Stress; Parkinson Disease; Selegiline; Vitamin E

1995
Dietary lipids and antioxidants in Parkinson's disease: a population-based, case-control study.
    Annals of neurology, 1996, Volume: 39, Issue:1

    Topics: Aged; Aged, 80 and over; Antioxidants; Ascorbic Acid; Case-Control Studies; Diet Surveys; Dietary Carbohydrates; Dietary Fats; Dietary Proteins; Energy Intake; Female; Humans; Lipid Peroxidation; Male; Odds Ratio; Parkinson Disease; Vitamin A; Vitamin E; Vitamins

1996
A 61-year-old man with Parkinson's disease.
    JAMA, 1996, Mar-06, Volume: 275, Issue:9

    Topics: 1-Naphthylamine; Antiparkinson Agents; Carbidopa; Depression; Dopamine Agents; Drug Interactions; Drug Therapy, Combination; Family Practice; Humans; Levodopa; Male; Middle Aged; Neurology; Neuroprotective Agents; Parkinson Disease; Selegiline; Sertraline; Vitamin E

1996
Case-control study of idiopathic Parkinson's disease and dietary vitamin E intake.
    Neurology, 1996, Volume: 46, Issue:5

    Topics: Aged; Aged, 80 and over; Case-Control Studies; Cohort Studies; Diet; Feeding Behavior; Follow-Up Studies; Hawaii; Humans; Japan; Parkinson Disease; Surveys and Questionnaires; Time Factors; Vitamin E

1996
Plasma levels of vitamin E in Parkinson's disease.
    Journal of neural transmission. Supplementum, 1995, Volume: 45

    Topics: Aged; Aging; Antioxidants; Case-Control Studies; Female; Humans; Italy; Male; Parkinson Disease; Vitamin E

1995
Alpha-tocopherol in the ventricular cerebrospinal fluid of Parkinson's disease patients: dose-response study and correlations with plasma levels.
    Neurology, 1996, Volume: 47, Issue:4

    Topics: Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Parkinson Disease; Vitamin E

1996
Study design problems of DATATOP study analysis.
    Annals of neurology, 1996, Volume: 40, Issue:6

    Topics: Clinical Trials as Topic; Humans; Levodopa; Parkinson Disease; Placebos; Randomized Controlled Trials as Topic; Selegiline; Vitamin E

1996
Dietary antioxidants and other dietary factors in the etiology of Parkinson's disease.
    Movement disorders : official journal of the Movement Disorder Society, 1997, Volume: 12, Issue:2

    Topics: Adult; Aged; Antioxidants; Ascorbic Acid; Carotenoids; Case-Control Studies; Feeding Behavior; Free Radicals; Humans; Male; Mental Status Schedule; Middle Aged; Neurologic Examination; Nutritional Requirements; Parkinson Disease; Risk Factors; Vitamin E

1997
(E)-4-hydroxy-2-nonenal may be involved in the pathogenesis of Parkinson's disease.
    Free radical biology & medicine, 1998, Jul-15, Volume: 25, Issue:2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Adult; Aged; Aldehydes; Animals; Brain Stem; Cross-Linking Reagents; Drug Administration Routes; Glutathione; Humans; Injections, Subcutaneous; Male; Mice; Middle Aged; Parkinson Disease; Substantia Nigra; Time Factors; Vitamin E

1998
To E or not to E: how much is the question.
    Health news (Waltham, Mass.), 1999, Dec-15, Volume: 5, Issue:15

    Topics: Alzheimer Disease; Antioxidants; Female; Heart Diseases; Humans; Male; Parkinson Disease; Vitamin E

1999
Aging of the brain and vitamin E.
    Journal of nutritional science and vitaminology, 1992, Volume: Spec No

    Topics: Aging; Animals; Brain; Catechols; Ferric Compounds; Humans; Lipid Peroxidation; Membrane Lipids; Parkinson Disease; Vitamin E

1992
Therapy of Parkinson's disease: are we at the end of the road?
    The Journal of the Association of Physicians of India, 1992, Volume: 40, Issue:6

    Topics: Antiparkinson Agents; Dopamine Agents; Humans; India; Levodopa; Neurologic Examination; Parkinson Disease; Selegiline; Vitamin E

1992
Concentrations of vitamins A, C and E in elderly patients with Parkinson's disease.
    Postgraduate medical journal, 1992, Volume: 68, Issue:802

    Topics: Aged; Aged, 80 and over; Ascorbic Acid; Cholesterol; Female; Humans; Leukocytes; Male; Middle Aged; Parkinson Disease; Vitamin A; Vitamin E

1992
Alpha-tocopherol levels in brain are not altered in Parkinson's disease.
    Annals of neurology, 1992, Volume: 32, Issue:4

    Topics: Aged; Brain Chemistry; Cerebellum; Female; Humans; Lipids; Male; Parkinson Disease; Reference Values; Vitamin E

1992
A pilot trial of high-dose alpha-tocopherol and ascorbate in early Parkinson's disease.
    Annals of neurology, 1992, Volume: 32 Suppl

    Topics: Adult; Aged; Ascorbic Acid; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Parkinson Disease; Pilot Projects; Research Design; Vitamin E

1992
Serum levels of alpha-tocopherol (vitamin E) in Parkinson's disease.
    Neurology, 1992, Volume: 42, Issue:5

    Topics: Aged; Analysis of Variance; Chromatography, High Pressure Liquid; Female; Humans; Male; Parkinson Disease; Vitamin E

1992
Alzheimer's and Parkinson's disease. Brain levels of glutathione, glutathione disulfide, and vitamin E.
    Molecular and chemical neuropathology, 1991, Volume: 14, Issue:3

    Topics: Aged; Alzheimer Disease; Brain; Glutathione; Glutathione Disulfide; Humans; Parkinson Disease; Vitamin E

1991
Many researchers, few clinicians, using drug that may slow, even prevent, Parkinson's.
    JAMA, 1990, Sep-05, Volume: 264, Issue:9

    Topics: Humans; Parkinson Disease; Selegiline; Vitamin E

1990
Clinical neuromythology IX. Pyramid sale in the bucket shop: DATATOP bottoms out.
    Neurology, 1990, Volume: 40, Issue:9

    Topics: Humans; Parkinson Disease; Phenethylamines; Selegiline; Vitamin E

1990
Monoamine oxidase and the bioactivation of MPTP and related neurotoxins: relevance to DATATOP.
    Journal of neural transmission. Supplementum, 1990, Volume: 32

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Biotransformation; Brain; Humans; In Vitro Techniques; Male; Mice; Monoamine Oxidase; Nervous System; Neurotoxins; Oxidation-Reduction; Parkinson Disease; Rats; Rats, Inbred Strains; Selegiline; Vitamin E

1990
Vitamin E and Parkinson's disease.
    Lancet (London, England), 1987, Feb-28, Volume: 1, Issue:8531

    Topics: Food, Fortified; Humans; Male; Middle Aged; Parkinson Disease; Vitamin E

1987
The potential use of vitamin E and selenium in parkinsonism.
    Medical hypotheses, 1986, Volume: 20, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Disease Models, Animal; Humans; Hydroxydopamines; Neurons; Oxidopamine; Parkinson Disease; Pyridines; Rats; Selenium; Vitamin E

1986
[Biochemistry of the physiopathologic and clinical aspects of free radicals in cerebral degenerative diseases such as Alzheimer's and Parkinson diseases].
    Nihon rinsho. Japanese journal of clinical medicine, 1988, Volume: 46, Issue:10

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Alzheimer Disease; Animals; Catecholamines; Free Radicals; Humans; Lipid Peroxides; Monoamine Oxidase; Parkinson Disease; Pyridines; Superoxide Dismutase; Vitamin E

1988