Page last updated: 2024-08-21

d-alpha tocopherol and Down Syndrome

d-alpha tocopherol has been researched along with Down Syndrome in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19906 (35.29)18.7374
1990's4 (23.53)18.2507
2000's1 (5.88)29.6817
2010's6 (35.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ali Keshawarz, S; Ali Mahboob, S; Mustafa Nachvak, S; Reza Neyestani, T; Sabour, S; Speakman, JR1
Hagihara, Y; Ishida, N; Iwahashi, H; Niki, E; Shichiri, M; Tamai, H; Yoshida, Y1
Doran, E; Gillen, DL; Head, E; Lott, IT; Nguyen, VQ; Tournay, A1
Dalmarco, EM; Dalmarco, JB; de Medeiros, Gda S; Garlet, TR; Moreira, EA; Parisotto, EB; Pereira, LC; Wilhelm Filho, D1
Bastos, J; Cavalli, VL; da Rosa, JS; Fröde, TS; Garlet, TR; Micke, GA; Parisotto, EB; Pedrosa, RC; Wilhelm Filho, D; Zamoner, A1
Aisen, PS; Andrews, HF; Dalton, AJ; Lai, F; Sano, M; Tsai, WY1
Coifman, RE1
Dickerson, JW; Edwards, D; Matin, MA; Sylvester, PE1
Brandi, N; Cabré, E; Doladé, M; Mira, A; Navarro, E; Pastor, MC; Serés, A; Sierra, C1
Heinemann, U; Müller, W; Schuchmann, S1
de la Torre, C; Navarrete, MH; Pincheira, J; Santos, MJ; Tapia, G1
Cerruti-Harris, C; Glozman, S; Groner, Y; Yavin, E1
Antila, E; Nordberg, UR; Syväoja, EL; Westermarck, T1
Bowen, DM; Metcalfe, T; Muller, DP2
Brás, A; Monteiro, C; Rueff, J1
Dickerson, JW; Holland, AJ; Jackson, CV; Williams, CA1

Trials

4 trial(s) available for d-alpha tocopherol and Down Syndrome

ArticleYear
α-Tocopherol supplementation reduces biomarkers of oxidative stress in children with Down syndrome: a randomized controlled trial.
    European journal of clinical nutrition, 2014, Volume: 68, Issue:10

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Adolescent; alpha-Tocopherol; Antioxidants; Biomarkers; Child; Deoxyguanosine; Dietary Supplements; Down Syndrome; Female; Humans; Male; Malondialdehyde; Oxidation-Reduction; Oxidative Stress; Thiobarbituric Acid Reactive Substances

2014
Down syndrome and dementia: a randomized, controlled trial of antioxidant supplementation.
    American journal of medical genetics. Part A, 2011, Volume: 155A, Issue:8

    Topics: alpha-Tocopherol; Alzheimer Disease; Antioxidants; Ascorbic Acid; Down Syndrome; Drug Combinations; Feasibility Studies; Female; Humans; Male; Middle Aged; Pilot Projects; Thioctic Acid; Treatment Outcome

2011
Vitamin E in aging persons with Down syndrome: A randomized, placebo-controlled clinical trial.
    Neurology, 2016, May-31, Volume: 86, Issue:22

    Topics: Administration, Oral; Apolipoproteins E; Cognitive Dysfunction; Dementia; Double-Blind Method; Down Syndrome; Female; Humans; Male; Middle Aged; Neuropsychological Tests; Nootropic Agents; Treatment Failure; Vitamin E

2016
Management of a potentially harmful health behavior by clinical trial.
    Pediatrics, 1980, Volume: 66, Issue:2

    Topics: Attitude to Health; Child; Clinical Trials as Topic; Communication; Double-Blind Method; Down Syndrome; Female; Humans; Physician-Patient Relations; Placebos; Professional-Family Relations; Respiratory Tract Infections; Vitamin E

1980

Other Studies

13 other study(ies) available for d-alpha tocopherol and Down Syndrome

ArticleYear
α-Tocopherol suppresses lipid peroxidation and behavioral and cognitive impairments in the Ts65Dn mouse model of Down syndrome.
    Free radical biology & medicine, 2011, Jun-15, Volume: 50, Issue:12

    Topics: alpha-Tocopherol; Animals; Animals, Newborn; Brain; Cognition Disorders; Dinoprost; Disease Models, Animal; Down Syndrome; Fatty Acids, Unsaturated; Female; Free Radicals; Hippocampus; Hydroxycholesterols; Lipid Peroxidation; Maze Learning; Mice; Mice, Neurologic Mutants; Oxidative Stress; Pregnancy; Prenatal Exposure Delayed Effects; Space Perception

2011
Systemic oxidative stress in children and teenagers with Down syndrome.
    Life sciences, 2013, Oct-11, Volume: 93, Issue:16

    Topics: Antioxidants; Biomarkers; Case-Control Studies; Child; Child, Preschool; Down Syndrome; Female; Humans; Male; Oxidative Stress; Protein Carbonylation; Thiobarbituric Acid Reactive Substances; Uric Acid; Vitamin E

2013
Antioxidant intervention attenuates oxidative stress in children and teenagers with Down syndrome.
    Research in developmental disabilities, 2014, Volume: 35, Issue:6

    Topics: Adolescent; Antioxidants; Ascorbic Acid; Biomarkers; Case-Control Studies; Catalase; Child; Child, Preschool; Dietary Supplements; Down Syndrome; Female; gamma-Glutamyltransferase; Glucosephosphate Dehydrogenase; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Humans; Male; Oxidative Stress; Peroxidase; Protein Carbonylation; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Uric Acid; Vitamin E

2014
Vitamin and zinc status in Down syndrome.
    Journal of mental deficiency research, 1981, Volume: 25, Issue:Pt 2

    Topics: Adult; Ascorbic Acid; Down Syndrome; Female; Humans; Middle Aged; Nicotinic Acids; Skin Diseases; Thiamine; Vitamin A; Vitamin E; Vitamins; Zinc

1981
Antioxidant enzymes and fatty acid status in erythrocytes of Down's syndrome patients.
    Clinical chemistry, 1998, Volume: 44, Issue:5

    Topics: Adolescent; Adult; Age Factors; Antioxidants; Catalase; Catalysis; Child; Child, Preschool; Down Syndrome; Erythrocyte Membrane; Erythrocytes; Fatty Acids; Glutathione Peroxidase; Glutathione Reductase; Humans; Infant; Middle Aged; Superoxide Dismutase; Superoxide Dismutase-1; Triglycerides; Vitamin E

1998
Altered Ca2+ signaling and mitochondrial deficiencies in hippocampal neurons of trisomy 16 mice: a model of Down's syndrome.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1998, Sep-15, Volume: 18, Issue:18

    Topics: Aging; Alzheimer Disease; Animals; Calcium; Carcinogens; Cell Death; Cyclosporine; Diploidy; Disease Models, Animal; Down Syndrome; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Hippocampus; Karyotyping; Male; Membrane Potentials; Mice; Mice, Neurologic Mutants; Mitochondria; NADP; Neurons; Potassium; Quinoxalines; Signal Transduction; Trisomy; Vitamin E

1998
Effect of vitamin E on chromosomal aberrations in lymphocytes from patients with Down's syndrome.
    Clinical genetics, 1999, Volume: 55, Issue:3

    Topics: Caffeine; Child, Preschool; Chromosome Aberrations; Down Syndrome; Female; G2 Phase; Humans; Infant; Lymphocytes; Male; Statistics as Topic; Vitamin E

1999
Docosahexaenoic acid-deficient phosphatidyl serine and high alpha-tocopherol in a fetal mouse brain over-expressing Cu/Zn-superoxide dismutase.
    Biochimica et biophysica acta, 2000, Sep-27, Volume: 1487, Issue:2-3

    Topics: Animals; Antioxidants; Brain; Docosahexaenoic Acids; Down Syndrome; Humans; Mice; Mice, Transgenic; Phosphatidylserines; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Vitamin E

2000
Selenium therapy in Down syndrome (DS): a theory and a clinical trial.
    Advances in experimental medicine and biology, 1990, Volume: 264

    Topics: Adolescent; Adult; Child; Child, Preschool; Down Syndrome; Erythrocytes; Female; Glutathione Peroxidase; Humans; Infant; Male; Middle Aged; Selenium; Superoxide Dismutase; Vitamin E

1990
Vitamin E concentrations in human brain of patients with Alzheimer's disease, fetuses with Down's syndrome, centenarians, and controls.
    Neurochemical research, 1989, Volume: 14, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Aging; Alzheimer Disease; Brain; Down Syndrome; Fetus; Humans; Middle Aged; Vitamin E

1989
Oxidative stress in trisomy 21. A possible role in cataractogenesis.
    Ophthalmic paediatrics and genetics, 1989, Volume: 10, Issue:4

    Topics: Adolescent; Adult; Ascorbic Acid; Cataract; Child; Child, Preschool; Down Syndrome; Erythrocytes; Free Radicals; Humans; Infant; Lipid Peroxidation; Oxygen; Superoxide Dismutase; Thiobarbiturates; Uric Acid; Vitamin E

1989
Vitamin E in brains of patients with Alzheimer's disease and Down's syndrome.
    Lancet (London, England), 1986, May-10, Volume: 1, Issue:8489

    Topics: Aged; Alzheimer Disease; Brain Chemistry; Down Syndrome; Humans; Vitamin E

1986
Vitamin E and Alzheimer's disease in subjects with Down's syndrome.
    Journal of mental deficiency research, 1988, Volume: 32 ( Pt 6)

    Topics: Adult; Alzheimer Disease; Down Syndrome; Female; Humans; Male; Middle Aged; Risk Factors; Vitamin E; Vitamin E Deficiency

1988