Page last updated: 2024-08-21

d-alpha tocopherol and Carcinoma, Hepatocellular

d-alpha tocopherol has been researched along with Carcinoma, Hepatocellular in 93 studies

Research

Studies (93)

Timeframe	Studies, this research(%)	All Research%
pre-1990	4 (4.30)	18.7374
1990's	27 (29.03)	18.2507
2000's	23 (24.73)	29.6817
2010's	27 (29.03)	24.3611
2020's	12 (12.90)	2.80

Authors

Authors	Studies
Gui, S; Guo, J; He, N; Huang, Y; Li, Z; Liang, X; Tang, M; Tao, Y	1
Attia, Y; El-Nabarawi, M; Mahmoud, K; Swidan, S; Teaima, M	1
De Zio, D; Di Leo, L; Filomeni, G; Mandatori, S; Rizza, S	1
Hu, Y; Jiang, S; Li, M; Lv, H; Zhang, Z	1
Abnet, CC; Albanes, D; Butt, J; Dawsey, SM; Freedman, ND; Koshiol, J; Lai, GY; McGlynn, KA; Michel, A; Murphy, G; Parisi, D; Pawlita, M; Snyder, K; Taylor, PR; Virtamo, J; Weinstein, SJ	1
Nishino, H	2
Caro, AA; Cederbaum, AI	1
Jun, HS; Kim, SE; Sung, MK	1
Cai, D; Guo, J; Min, J; Zhao, F	3
Itoshima, T; Kawaguchi, M; Okita, M; Osawa, T; Ota, Y; Sakai, N; Sasagawa, T; Tomioka, K	1
Hashimoto, Y; Kabeya, K; Kakizaki, S; Kaneko, M; Konaka, K; Mori, M; Nagamine, T; Sato, K; Shimojo, H; Sohara, N; Tago, Y; Takagi, H; Takahashi, H; Takayama, H; Tsukioka, G; Yamada, T	1
Bulla, GA; Kraus, DM; Schmitz, EK	1
Hosotani, K; Inui, H; Kawahata, A; Koyama, K; Murakami, C; Nakano, Y; Yamaji, R; Yoshida, H	1
Barella, L; Fischer, A; Rimbach, G; Stoecklin, E	1
Chuang, CH; Hu, ML; Huang, CS; Shih, MK	1
Cederbaum, AI; Chen, Q; Galleano, M	1
Fujii, H; Hara, N; Itoh, Y; Nakajima, A; Okanoue, T; Seko, Y; Sumida, Y; Takahashi, H; Yoneda, M	1
Alvarez, ML; Carrillo, MC; Ceballos, MP; Comanzo, CG; Ferretti, AC; Lorenzetti, F; Lucci, A; Quiroga, AD; Vera, MC	1
Li, X; Li, Z; Lian, D; Liu, J; Ye, L	1
Chen, H; Li, W; Lu, Y; Tao, R; Wang, C; Zhang, C; Zhou, H	1
Kurmi, BD; Paliwal, R; Paliwal, SR; Tekchandani, P	1
Li, D; Liu, S; Shen, L; Zhang, QY; Zhu, H; Zhu, J	1
Seen, S	1
Du, Z; Fu, J; Hu, J; Mao, Y; Yin, J; You, Q; Zhang, P	1
Huang, QF; Jiang, YY; Liu, M; Lu, XX; Shao, CL; Wang, GH; Zhang, JM	1
Chan, HL; Chan, WK; Chawla, Y; Chitturi, S; Dan, YY; Duseja, A; Fan, J; Farrell, G; Goh, KL; Hamaguchi, M; Hashimoto, E; Kim, SU; Lesmana, LA; Lin, YC; Liu, CJ; Ni, YH; Sollano, J; Wong, GL; Wong, SK; Wong, VW	1
Bian, J; Cai, J; Luo, S; Tsend-Ayush, A; Wen, J; Yao, J; Yin, L; Yuan, Z; Zhou, J; Zhu, X	1
Adachi, T; Okada, H; Takaki, A; Uchida, D	1
Chaiyakunapruk, N; Chongmelaxme, B; Dilokthornsakul, P; Phisalprapa, P; Sawangjit, R	1
Chen, D; Gao, J; Lu, Y; Pan, X; Xie, F; Yin, C; Zhang, Y; Zou, H	1
Li, A; Liang, Y; Lyu, Y; Tang, X; Xie, D; Zheng, D	1
Burdeos, GC; Kimura, F; Miyazawa, T; Nakagawa, K; Watanabe, A	1
Baccino, FM; Bonelli, G; Costelli, P; Khadjavi, A; Minero, VG	1
Chu, M; Guo, Y; Liu, H; Otieno, BO; Tan, S; Xu, C; Yang, X; Zhang, Z; Zhao, S	1
Ahn, KS; Fong, CW; Hui, KM; Kumar, AP; Li, F; Ong, TH; Sethi, G; Shanmugam, MK; Siveen, KS; Tergaonkar, V; Yap, WN	1
Bao, X; Chu, QC; Gao, M; Guan, X; Jiang, N; Liu, KX; Tian, Y; Xu, H; Zhang, CH	1
Guo, Y; Si, L; Song, Q; Tan, S; Wu, T; Ye, Q; Zhang, Z; Zhao, Y; Zhuang, X	1
Chen, M; Fang, X; Li, Y; Wang, Y; Zhang, J; Zhou, D	1
Halilbasic, E; Hofer, H; Kazemi-Shirazi, L; Kienbacher, C; Munda, P; Rechling, C; Trauner, M; Traussnigg, S	1
Andreo, U; Branch, AD; Chung, HY; Espiritu, C; Rice, CM; Saeed, M; Silva, JM	1
Liu, G; Mei, L; Tao, W; Wang, T; Zeng, X; Zhang, H; Zhang, L; Zhu, D	1
Burdeos, GC; Eitsuka, T; Ito, J; Kimura, F; Miyazawa, T; Nakagawa, K	1
Cheng, SB; Huang, YC; Huang, YT; Lin, PT; Liu, HT	2
Oseini, AM; Sanyal, AJ	1
Hsiao, JK; Huang, JC; Lee, KT; Lin, SK; Ma, H; Tsai, LY; Tsai, SM; Wu, SH	1
Chang, CP; Nesaretnam, K; Ong, S; Shiba, S; Teo, VH; Xu, CH; Yap, WN; Yap, YL; Zaiden, N; Zhang, XW	1
Kumar, AP; Li, F; Loo, SY; Manu, KA; Rajendran, P; Sethi, G; Shanmugam, MK	1
Abbott-Johnson, W; Clague, A; Cuneo, R; Johnson, H; Kerlin, P	1
Lu, Y; Shan, W; Wang, T; Xiong, S; Yin, X	1
Bril, F; Cusi, K; Lomonaco, R; Sunny, NE	1
Cetin-Atalay, R; Ince, G; Irmak, MB; Ozturk, M	1
Fabbroni, V; Fabrizio, P; Fantappiè, O; Lasagna, N; Lodovici, M; Marchettia, S; Mazzanti, R; Pantaleo, P; Solazzo, M	1
Atkinson, J; Manor, D; Morley, S; Nava, P; Qian, J; Wilson, K	1
Lin, CC; Ng, LT; Wu, SJ	1
Adamsky, K; Amariglio, N; Breda, L; Cabantchik, ZI; Rachmilewitz, EA; Rechavi, G; Rivella, S; Weizer-Stern, O	1
Okabe, M; Sakai, M; Tachibana, H; Yamada, K	1
Ando, T; Hagiwara, S; Kakizaki, S; Kori, T; Mori, M; Nagasaka, K; Ohno, Y; Otsuka, T; Takagi, H; Takahashi, T; Takeuchi, K; Tojima, H; Tomioka, S; Yoshida, H	1
Gorozhanskaia, EG; Patiutko, II; Sagaidak, IV	1
Bassi, A; Capra, F; Casaril, M; Corrocher, R; Corso, F; Gabrielli, GB; Nicoli, N; Stanzial, AM	1
Burke, MD; Duthie, SJ; Melvin, WT	1
Huang, SM; Liaw, YF; Lin, DI; Lin, WG; Pan, WH; Wang, CY; Yeh, SY	1
Clark, RW; Gordon, DA; Parker, RA; Pearce, BC; Wright, JJ	1
Brewster, MA; Turley, CP	1
Høstmark, AT; Kierulf, P; Kiserud, CE	1
Atger, V; Cogny, A; Moatti, N; Paul, JL; Soni, T	1
Descampiaux, B; Erb, F; Leroux, JM; Peucelle, C	1
Moriwaki, H; Muto, Y; Nakamura, N; Shidoji, Y	1
Failla, ML; Loo, G; Martin, KR	1
Chamuleau, RA; Groenink, M; Hoek, FJ; Reitsma, PH; van Deventer, SJ; Wu, CG	1
Borghi, A; Camellini, L; Casalgrandi, G; Cioni, G; D'Alimonte, P; Rocchi, E; Seium, Y	1
Esaki, H; Matsuo, M; Muto, Y; Nakamura, N; Osawa, T; Shidoji, Y	1
Yamamoto, Y; Yamashita, S	2
Henning, SM; Ivandic, BT; Liao, F; Swendseid, ME	1
Hirai, T; Iwata, T; Kuwahara, M; Toge, T; Yamashita, Y; Yoshimoto, A	1
Goti, D; Kostner, GM; Malle, E; Panzenboeck, U; Reicher, H; Sattler, W	1
Fujisawa, A; Kokura, S; Yamamoto, Y; Yamashita, S; Yoshikawa, T	1
Frøyen, P; Høstmark, AT; Jebens, E; Lystad, E; Skramstad, J	1
Brigelius-Flohé, R; Elsner, A; Gawlik, D; Leist, M; Maurer, S; Schultz, M	1
Premalatha, B; Sachdanandam, P	1
Eriksson, LC; Olsson, JM; Stål, P; Wang, GS	1
Cederbaum, AI; Marí, M	1
Kang, JH; Shi, YM; Zheng, RL	1
Hobara, N; Watanabe, A	1
Høstmark, AT; Lystad, E	1
Bonkovsky, HL	1
Kanematsu, T; Kawano, T; Kuwano, M; Matsumata, T; Sugimachi, K; Takenaka, K	1
Chen, YT; Ding, JH	1
Dickie, MM; Hancock, RL	1

Reviews

8 review(s) available for d-alpha tocopherol and Carcinoma, Hepatocellular

Article	Year
Chronic liver disease and oxidative stress - a narrative review. Expert review of gastroenterology & hepatology, 2021, Volume: 15, Issue:9 Topics: Animals; Antioxidants; Antiviral Agents; Carcinoma, Hepatocellular; Chronic Disease; Dietary Supplements; Flavonoids; Hepatitis B, Chronic; Hepatitis C, Chronic; Humans; Liver Cirrhosis; Liver Diseases; Liver Diseases, Alcoholic; Liver Neoplasms; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Reactive Oxygen Species; Vitamin E	2021
The Asia-Pacific Working Party on Non-alcoholic Fatty Liver Disease guidelines 2017-Part 2: Management and special groups. Journal of gastroenterology and hepatology, 2018, Volume: 33, Issue:1 Topics: Adolescent; Asia; Bariatric Surgery; Carcinoma, Hepatocellular; Chenodeoxycholic Acid; Child; Diet; Exercise; Fatty Acids, Omega-3; Gastroenterology; Humans; Liver Neoplasms; Liver Transplantation; Non-alcoholic Fatty Liver Disease; Obesity; Pacific Islands; Practice Guidelines as Topic; Risk; Systematic Reviews as Topic; Thiazolidinediones; Vitamin E	2018
Beneficial and Paradoxical Roles of Anti-Oxidative Nutritional Support for Non-Alcoholic Fatty Liver Disease. Nutrients, 2018, Jul-27, Volume: 10, Issue:8 Topics: Antioxidants; Carcinoma, Hepatocellular; Contraindications, Drug; End Stage Liver Disease; Humans; Liver; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Vitamin E	2018
Challenges and Management of Liver Cirrhosis: Practical Issues in the Therapy of Patients with Cirrhosis due to NAFLD and NASH. Digestive diseases (Basel, Switzerland), 2015, Volume: 33, Issue:4 Topics: Anticholesteremic Agents; Antioxidants; Bariatric Surgery; Carcinoma, Hepatocellular; Disease Progression; Genetic Variation; Humans; Hypoglycemic Agents; Lipase; Liver; Liver Cirrhosis; Liver Neoplasms; Liver Transplantation; Membrane Proteins; Metabolic Syndrome; Metformin; Non-alcoholic Fatty Liver Disease; Obesity, Morbid; Prognosis; Receptors, Cytoplasmic and Nuclear; Vitamin E	2015
Therapies in non-alcoholic steatohepatitis (NASH). Liver international : official journal of the International Association for the Study of the Liver, 2017, Volume: 37 Suppl 1 Topics: Carcinoma, Hepatocellular; Diet; Disease Progression; Exercise; Fibrosis; Humans; Hypoglycemic Agents; Liver; Liver Cirrhosis; Liver Neoplasms; Liver Transplantation; Non-alcoholic Fatty Liver Disease; Pioglitazone; Randomized Controlled Trials as Topic; Risk Factors; Thiazolidinediones; Vitamin E	2017
Nonalcoholic fatty liver disease: current issues and novel treatment approaches. Drugs, 2013, Volume: 73, Issue:1 Topics: Carcinoma, Hepatocellular; Fatty Liver; Humans; Hypoglycemic Agents; Insulin Resistance; Non-alcoholic Fatty Liver Disease; Pioglitazone; Randomized Controlled Trials as Topic; Thiazolidinediones; Vitamin E; Weight Loss	2013
Role of iron in inducing oxidative stress in thalassemia: Can it be prevented by inhibition of absorption and by antioxidants? Annals of the New York Academy of Sciences, 2005, Volume: 1054 Topics: Acetylcysteine; Animals; Antimicrobial Cationic Peptides; Antioxidants; Bone Marrow; Carcinoma, Hepatocellular; Cell Line, Tumor; Disease Models, Animal; Drug Therapy, Combination; Erythrocytes; Gene Expression Regulation; Genetic Therapy; Hepcidins; Humans; Intestinal Absorption; Iron; Iron Chelating Agents; Iron, Dietary; Liver Neoplasms; Mice; Oxidants; Oxidative Stress; Thalassemia; Vitamin E	2005
Iron and the liver. The American journal of the medical sciences, 1991, Volume: 301, Issue:1 Topics: Ascorbic Acid; Carcinoma, Hepatocellular; Collagen; Free Radicals; Hemochromatosis; Humans; Iron; Liver; Liver Cirrhosis; Liver Neoplasms; Lysosomes; Membrane Potentials; Porphyrias; Potassium; Transferrin; Uroporphyrins; Vitamin E	1991

Trials

4 trial(s) available for d-alpha tocopherol and Carcinoma, Hepatocellular

Article	Year
Phytochemicals in hepatocellular cancer prevention. Nutrition and cancer, 2009, Volume: 61, Issue:6 Topics: alpha-Tocopherol; Animals; Anticarcinogenic Agents; beta Carotene; Carcinoma, Hepatocellular; Carotenoids; Cryptoxanthins; Dietary Supplements; Hepatitis, Viral, Human; Humans; Inositol; Kaplan-Meier Estimate; Liver Cirrhosis; Liver Neoplasms; Lycopene; Male; Mice; Mice, Inbred C3H; Tumor Burden; Xanthophylls	2009
Pilot clinical trial of the use of alpha-tocopherol for the prevention of hepatocellular carcinoma in patients with liver cirrhosis. International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 2003, Volume: 73, Issue:6 Topics: Alanine Transaminase; alpha-Fetoproteins; alpha-Tocopherol; Antioxidants; Carcinoma, Hepatocellular; Cholesterol; Female; Hepatitis C, Chronic; Humans; Liver Cirrhosis; Liver Neoplasms; Male; Middle Aged; Pilot Projects; Platelet Count; Serum Albumin; Survival Rate	2003
Prevention of hepatocellular carcinoma in chronic viral hepatitis patients with cirrhosis by carotenoid mixture. Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 2007, Volume: 174 Topics: alpha-Tocopherol; Carcinoma, Hepatocellular; Carotenoids; Female; Hepatitis C; Hepatitis, Viral, Human; Humans; Liver Cirrhosis; Liver Neoplasms; Male; Middle Aged	2007
Effects of coenzyme Q10 supplementation on antioxidant capacity and inflammation in hepatocellular carcinoma patients after surgery: a randomized, placebo-controlled trial. Nutrition journal, 2016, 10-06, Volume: 15, Issue:1 Topics: Aged; Antioxidants; Biomarkers; Body Mass Index; Body Weight; C-Reactive Protein; Carcinoma, Hepatocellular; Catalase; Dietary Supplements; Female; Humans; Inflammation; Interleukin-6; Linear Models; Liver Neoplasms; Male; Malondialdehyde; Middle Aged; Oxidative Stress; Single-Blind Method; Superoxide Dismutase; Ubiquinone; Vitamin E	2016

Other Studies

81 other study(ies) available for d-alpha tocopherol and Carcinoma, Hepatocellular

Article	Year
Sorafenib-Loaded PLGA-TPGS Nanosystems Enhance Hepatocellular Carcinoma Therapy Through Reversing P-Glycoprotein-Mediated Multidrug Resistance. AAPS PharmSciTech, 2022, Apr-29, Volume: 23, Issue:5 Topics: alpha-Tocopherol; Animals; ATP Binding Cassette Transporter, Subfamily B; Carcinoma, Hepatocellular; Drug Resistance, Multiple; Glycolates; Humans; Lactic Acid; Liver Neoplasms; Mice; Mice, Nude; Polyesters; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Sorafenib; Vitamin E	2022
Size-optimized simvastatin-loaded TPGS modified lipid nanocapsules for targeting epithelial-to-mesenchymal transition in hepatocellular carcinoma: Role of PTEN/AKT signaling. Expert opinion on drug delivery, 2023, Volume: 20, Issue:5 Topics: alpha-Tocopherol; Carcinoma, Hepatocellular; Cell Line, Tumor; Humans; Lipids; Liver Neoplasms; Nanocapsules; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Simvastatin; Tissue Distribution	2023
Mitophagy contributes to alpha-tocopheryl succinate toxicity in GSNOR-deficient hepatocellular carcinoma. Biochemical pharmacology, 2020, Volume: 176 Topics: Aldehyde Oxidoreductases; alpha-Tocopherol; Antioxidants; Autophagosomes; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Hep G2 Cells; Humans; Liver Neoplasms; Microscopy, Confocal; Microscopy, Electron, Transmission; Mitochondria; Mitophagy; RNA Interference	2020
Multifunctional self-assembled micelles of galactosamine-hyaluronic acid-vitamin E succinate for targeting delivery of norcantharidin to hepatic carcinoma. Carbohydrate polymers, 2018, Oct-01, Volume: 197 Topics: alpha-Tocopherol; Animals; Antineoplastic Agents; Bridged Bicyclo Compounds, Heterocyclic; Carcinoma, Hepatocellular; Cell Proliferation; Dose-Response Relationship, Drug; Drug Delivery Systems; Drug Screening Assays, Antitumor; Female; Galactosamine; Hep G2 Cells; Humans; Hyaluronic Acid; Liver Neoplasms; Liver Neoplasms, Experimental; MCF-7 Cells; Mice; Mice, Inbred BALB C; Mice, Nude; Micelles; Molecular Structure; Structure-Activity Relationship	2018
Association of seropositivity to Helicobacter species and biliary tract cancer in the ATBC study. Hepatology (Baltimore, Md.), 2014, Volume: 60, Issue:6 Topics: alpha-Tocopherol; beta Carotene; Biliary Tract Neoplasms; Carcinoma, Hepatocellular; Case-Control Studies; Helicobacter Infections; Humans; Liver Neoplasms; Male; Middle Aged; Randomized Controlled Trials as Topic; Vitamins	2014
Ca2+-dependent and independent mitochondrial damage in HepG2 cells that overexpress CYP2E1. Archives of biochemistry and biophysics, 2002, Dec-15, Volume: 408, Issue:2 Topics: alpha-Tocopherol; Arachidonic Acid; Calcium; Calpain; Carcinoma, Hepatocellular; Culture Media; Cyclosporine; Cysteine Proteinase Inhibitors; Cytochrome P-450 CYP2E1; Cytosol; Dipeptides; Humans; Intracellular Membranes; Iron; Lipid Peroxidation; Liver Neoplasms; Mitochondria, Liver; Oxidative Stress; Permeability; Tumor Cells, Cultured	2002
Protective effect of soybean saponins and major antioxidants against aflatoxin B1-induced mutagenicity and DNA-adduct formation. Journal of medicinal food, 2002,Winter, Volume: 5, Issue:4 Topics: Aflatoxin B1; alpha-Tocopherol; Anticarcinogenic Agents; Antioxidants; Ascorbic Acid; Butylated Hydroxytoluene; Carcinoma, Hepatocellular; DNA Adducts; Dose-Response Relationship, Drug; Glycine max; Humans; Liver Neoplasms; Mutagenicity Tests; Mutagens; Mutation; Saponins; Treatment Outcome; Tumor Cells, Cultured	2002
[Effect of different vitamin E homologous analogues on human hepatoma cell HepG2 proliferation in vitro]. Wei sheng yan jiu = Journal of hygiene research, 2003, Volume: 32, Issue:1 Topics: alpha-Tocopherol; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Division; gamma-Tocopherol; Humans; Liver Neoplasms; Tocopherols; Tumor Cells, Cultured; Vitamin E	2003
[Effect of apoptosis induced by different vitamin E homologous analogues in human hepatoma cells (HepG2)]. Wei sheng yan jiu = Journal of hygiene research, 2003, Volume: 32, Issue:2 Topics: alpha-Tocopherol; Antineoplastic Agents; Antioxidants; Apoptosis; Carcinoma, Hepatocellular; gamma-Tocopherol; Humans; Liver Neoplasms; Tocopherols; Tumor Cells, Cultured; Vitamin E	2003
Arachidonic acid in mononuclear cells and its clinical significance in HCV cirrhotic patients. Nutrition (Burbank, Los Angeles County, Calif.), 2003, Volume: 19, Issue:9 Topics: Aged; alpha-Tocopherol; Arachidonic Acid; Carcinoma, Hepatocellular; Case-Control Studies; Chromatography, Gas; Chromatography, High Pressure Liquid; Disease Progression; Enzyme-Linked Immunosorbent Assay; Fatty Acids; Female; Hepatitis C; Humans; Leukocytes, Mononuclear; Liver Cirrhosis; Liver Neoplasms; Lymphocyte Count; Male; Middle Aged; Phospholipids; Platelet Count; Thiobarbituric Acid Reactive Substances; Tumor Necrosis Factor-alpha	2003
[Effect of apoptosis induced by different vitamin E homologous analogues in human hepatoma cells(HepG2)]. Wei sheng yan jiu = Journal of hygiene research, 2003, Volume: 32, Issue:4 Topics: alpha-Tocopherol; Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; DNA, Neoplasm; Dose-Response Relationship, Drug; gamma-Tocopherol; Humans; Liver Neoplasms; Tocopherols; Tumor Cells, Cultured; Vitamin E	2003
Tissue-specificity of apoptosis in hepatoma-derived cell lines. Apoptosis : an international journal on programmed cell death, 2004, Volume: 9, Issue:3 Topics: Acetylcysteine; alpha-Tocopherol; Animals; Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Culture Media, Serum-Free; Cycloheximide; Electrophoretic Mobility Shift Assay; Interleukin-1; Lipopolysaccharides; Liver Neoplasms; Protein Synthesis Inhibitors; Rats; Sorbitol; Transgenes; Tumor Necrosis Factor-alpha; Vinblastine; Vincristine	2004
Effect of carotenoids and ascorbic acid of Japanese persimmons on cellular lipid peroxidation in HepG2 cells. BioFactors (Oxford, England), 2004, Volume: 21, Issue:1-4 Topics: alpha-Tocopherol; Antioxidants; Ascorbic Acid; Biological Transport; Carcinoma, Hepatocellular; Carotenoids; Cell Line, Tumor; Diospyros; Humans; Japan; Lipid Peroxidation; Liver Neoplasms; Plant Extracts; Thiobarbituric Acid Reactive Substances; Vitamin A	2004
Modulation of hepatic gene expression by alpha-tocopherol in cultured cells and in vivo. Annals of the New York Academy of Sciences, 2004, Volume: 1031 Topics: alpha-Tocopherol; Animals; Carcinoma, Hepatocellular; Cells, Cultured; Gene Expression Regulation; Humans; Liver; Liver Neoplasms; Male; Nucleic Acid Hybridization; Oligonucleotide Array Sequence Analysis; Rats; Tumor Cells, Cultured	2004
Lycopene inhibits cell migration and invasion and upregulates Nm23-H1 in a highly invasive hepatocarcinoma, SK-Hep-1 cells. The Journal of nutrition, 2005, Volume: 135, Issue:9 Topics: alpha-Tocopherol; Anticarcinogenic Agents; Antioxidants; beta Carotene; Carcinoma, Hepatocellular; Carotenoids; Cell Line, Tumor; Cell Movement; Drug Combinations; Humans; Liver Neoplasms; Lycopene; Neoplasm Invasiveness; NM23 Nucleoside Diphosphate Kinases; Nucleoside-Diphosphate Kinase; Oxidation-Reduction; RNA, Messenger; Up-Regulation	2005
Cytotoxicity and apoptosis produced by arachidonic acid in Hep G2 cells overexpressing human cytochrome P4502E1. The Journal of biological chemistry, 1997, Jun-06, Volume: 272, Issue:23 Topics: alpha-Tocopherol; Antioxidants; Apoptosis; Ascorbic Acid; Aspirin; Carcinoma, Hepatocellular; Cell Survival; Chromans; Cytochrome P-450 CYP2E1; Deferoxamine; Humans; L-Lactate Dehydrogenase; Liver Neoplasms; Oleic Acid; Phenylenediamines; Propyl Gallate; Proto-Oncogene Proteins c-bcl-2; Recombinant Proteins; Transfection; Tumor Cells, Cultured; Vitamin E	1997
Role of vitamin E in the treatment of non-alcoholic steatohepatitis. Free radical biology & medicine, 2021, Volume: 177 Topics: Antifibrotic Agents; Carcinoma, Hepatocellular; Humans; Liver; Liver Neoplasms; Non-alcoholic Fatty Liver Disease; Vitamin E	2021
Delta-tocotrienol enhances the anti-tumor effects of interferon alpha through reactive oxygen species and Erk/MAPK signaling pathways in hepatocellular carcinoma cells. Canadian journal of physiology and pharmacology, 2022, Volume: 100, Issue:5 Topics: Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Humans; Interferon-alpha; Liver Neoplasms; Reactive Oxygen Species; Signal Transduction; Vitamin E	2022
Sorafenib-Loaded Nanoparticles Based on Biodegradable Dendritic Polymers for Enhanced Therapy of Hepatocellular Carcinoma. International journal of nanomedicine, 2020, Volume: 15 Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Dendrimers; Drug Delivery Systems; Hep G2 Cells; Humans; Liver Neoplasms; Mice; Nanoparticles; Polymers; Sorafenib; Vitamin E; Xenograft Model Antitumor Assays	2020
Characterization and Cytotoxicity of Polyprenol Lipid and Vitamin E-TPGS Hybrid Nanoparticles for Betulinic Acid and Low-Substituted Hydroxyl Fullerenol in MHCC97H and L02 Cells. International journal of nanomedicine, 2020, Volume: 15 Topics: Antineoplastic Agents; Betulinic Acid; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drug Delivery Systems; Drug Liberation; Fullerenes; Humans; Lipids; Liver Neoplasms; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Nanoparticles; Pentacyclic Triterpenes; Polyprenols; Triterpenes; Vitamin E	2020
Galactosylated TPGS Micelles for Docetaxel Targeting to Hepatic Carcinoma: Development, Characterization, and Biodistribution Study. AAPS PharmSciTech, 2020, Jun-16, Volume: 21, Issue:5 Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Line, Tumor; Docetaxel; Drug Delivery Systems; Drug Development; Female; Galactose; Hep G2 Cells; Humans; Liver Neoplasms; Male; Random Allocation; Rats; Tissue Distribution; Vitamin E	2020
Folic acid modified TPGS as a novel nano-micelle for delivery of nitidine chloride to improve apoptosis induction in Huh7 human hepatocellular carcinoma. BMC pharmacology & toxicology, 2021, 01-06, Volume: 22, Issue:1 Topics: Antineoplastic Agents; Apoptosis; Benzophenanthridines; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Drug Carriers; Drug Liberation; Folic Acid; Humans; Liver Neoplasms; Micelles; Nanoparticles; Vitamin E	2021
TPGS-Galactose-Modified Polydopamine Co-delivery Nanoparticles of Nitric Oxide Donor and Doxorubicin for Targeted Chemo-Photothermal Therapy against Drug-Resistant Hepatocellular Carcinoma. ACS applied materials & interfaces, 2021, Aug-04, Volume: 13, Issue:30 Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Line, Tumor; Doxorubicin; Drug Carriers; Drug Liberation; Drug Resistance, Neoplasm; Drug Therapy; Galactose; Humans; Indoles; Infrared Rays; Liver Neoplasms; Male; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Nitric Oxide Donors; Nitroso Compounds; Photothermal Therapy; Polymers; Rats, Sprague-Dawley; Vitamin E; Xenograft Model Antitumor Assays	2021
Brefeldin A delivery nanomicelles in hepatocellular carcinoma therapy: Characterization, cytotoxic evaluation in vitro, and antitumor efficiency in vivo. Pharmacological research, 2021, Volume: 172 Topics: Animals; Antineoplastic Agents; Apoptosis; Brefeldin A; Carcinoma, Hepatocellular; Cell Line; Cell Survival; Female; Humans; Liver Neoplasms; Mice, Inbred BALB C; Micelles; Nanostructures; Polyethylenes; Polypropylenes; Rats, Sprague-Dawley; Tissue Distribution; Vitamin E	2021
Glycyrrhetinic acid-modified TPGS polymeric micelles for hepatocellular carcinoma-targeted therapy. International journal of pharmaceutics, 2017, Aug-30, Volume: 529, Issue:1-2 Topics: Carcinoma, Hepatocellular; Drug Carriers; Etoposide; Glycyrrhetinic Acid; Humans; Micelles; Vitamin E	2017
Weight Reduction and Pioglitazone are Cost-Effective for the Treatment of Non-Alcoholic Fatty Liver Disease in Thailand. PharmacoEconomics, 2019, Volume: 37, Issue:2 Topics: Carcinoma, Hepatocellular; Cost-Benefit Analysis; Humans; Hypoglycemic Agents; Liver Cirrhosis; Liver Neoplasms; Markov Chains; Middle Aged; Non-alcoholic Fatty Liver Disease; Pioglitazone; Quality-Adjusted Life Years; Thailand; Vitamin E; Weight Loss; Weight Reduction Programs	2019
Codelivery of doxorubicin and elacridar to target both liver cancer cells and stem cells by polylactide-co-glycolide/d-alpha-tocopherol polyethylene glycol 1000 succinate nanoparticles. International journal of nanomedicine, 2018, Volume: 13 Topics: Acridines; Animals; Carcinoma, Hepatocellular; Cell Death; Doxorubicin; Drug Delivery Systems; Drug Synergism; Endocytosis; Hep G2 Cells; Humans; Liver Neoplasms; Male; Mice, Nude; Nanoparticles; Neoplastic Stem Cells; Polyesters; Polyethylene Glycols; Rats, Sprague-Dawley; Stem Cell Transplantation; Stem Cells; Subcutaneous Tissue; Tetrahydroisoquinolines; Tissue Distribution; Tumor Stem Cell Assay; Vitamin E	2018
Therapeutic Effect of Sorafenib-Loaded TPGS- Journal of biomedical nanotechnology, 2018, Feb-01, Volume: 14, Issue:2 Topics: Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Liver Neoplasms; Mice; Nanoparticles; Polyethylene Glycols; Sorafenib; Vitamin E	2018
γ-Tocotrienol attenuates triglyceride through effect on lipogenic gene expressions in mouse hepatocellular carcinoma Hepa 1-6. Journal of nutritional science and vitaminology, 2013, Volume: 59, Issue:2 Topics: Animals; Carcinoma, Hepatocellular; Carnitine O-Palmitoyltransferase; Cell Line, Tumor; Cholesterol; Chromans; Fatty Acid Synthases; Gene Expression; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipogenesis; Liver Neoplasms; Mice; Mice, Inbred C57BL; RNA, Messenger; Stearoyl-CoA Desaturase; Sterol Regulatory Element Binding Protein 1; Triglycerides; Vitamin E	2013
JNK activation is required for TNFα-induced apoptosis in human hepatocarcinoma cells. International immunopharmacology, 2013, Volume: 17, Issue:1 Topics: Anthracenes; Antioxidants; Apoptosis; Butylated Hydroxyanisole; Carcinoma, Hepatocellular; Caspases; Cell Line, Tumor; Chelating Agents; Cycloheximide; Deferoxamine; Humans; JNK Mitogen-Activated Protein Kinases; Liver Neoplasms; RNA Interference; RNA, Small Interfering; Signal Transduction; Tumor Necrosis Factor-alpha; Vitamin E	2013
Chitosan-g-TPGS nanoparticles for anticancer drug delivery and overcoming multidrug resistance. Molecular pharmaceutics, 2014, Jan-06, Volume: 11, Issue:1 Topics: Animals; Antibiotics, Antineoplastic; Apoptosis; Blotting, Western; Breast Neoplasms; Carcinoma, Hepatocellular; Cell Proliferation; Chitosan; Doxorubicin; Drug Delivery Systems; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Flow Cytometry; Humans; Liver Neoplasms; Mice; Nanoparticles; Polyethylene Glycols; Polymers; Tissue Distribution; Tumor Cells, Cultured; Vitamin E; Xenograft Model Antitumor Assays	2014
Y-tocotrienol inhibits angiogenesis-dependent growth of human hepatocellular carcinoma through abrogation of AKT/mTOR pathway in an orthotopic mouse model. Oncotarget, 2014, Apr-15, Volume: 5, Issue:7 Topics: Animals; Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Caspase 3; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Chick Embryo; Chromans; Endothelial Cells; Humans; Ki-67 Antigen; Liver Neoplasms; Mice; Mice, SCID; Models, Animal; Neovascularization, Pathologic; Proto-Oncogene Proteins c-akt; Signal Transduction; Vascular Endothelial Growth Factor A; Vitamin E	2014
A novel oleanolic acid-loaded PLGA-TPGS nanoparticle for liver cancer treatment. Drug development and industrial pharmacy, 2015, Volume: 41, Issue:7 Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Coumarins; Delayed-Action Preparations; Drug Carriers; Drug Liberation; Hep G2 Cells; Humans; Lactic Acid; Liver Neoplasms; Nanoparticles; Oleanolic Acid; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Solubility; Thiazoles; Vitamin E	2015
Nitric oxide releasing d-α-tocopheryl polyethylene glycol succinate for enhancing antitumor activity of doxorubicin. Molecular pharmaceutics, 2014, Nov-03, Volume: 11, Issue:11 Topics: Animals; Antibiotics, Antineoplastic; Apoptosis; Carcinoma, Hepatocellular; Doxorubicin; Drug Carriers; Female; Half-Life; Hep G2 Cells; Humans; Liver Neoplasms; Mice; Micelles; Nitric Oxide; Polyethylene Glycols; Rats, Sprague-Dawley; Sarcoma 180; Tissue Distribution; Vitamin E	2014
TPGS-g-PLGA/Pluronic F68 mixed micelles for tanshinone IIA delivery in cancer therapy. International journal of pharmaceutics, 2014, Dec-10, Volume: 476, Issue:1-2 Topics: Abietanes; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Biological Availability; Carcinoma, Hepatocellular; Delayed-Action Preparations; Drug Carriers; Drug Delivery Systems; Hep G2 Cells; Humans; Lactic Acid; Liver Neoplasms; Male; Micelles; Poloxamer; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Wistar; Serum Albumin, Bovine; Vitamin E	2014
SEC14L2 enables pan-genotype HCV replication in cell culture. Nature, 2015, Aug-27, Volume: 524, Issue:7566 Topics: Antioxidants; Carcinoma, Hepatocellular; Carrier Proteins; Cell Culture Techniques; Cell Line, Tumor; Cells, Cultured; Gene Library; Genome, Viral; Genotype; Hepacivirus; Host-Derived Cellular Factors; Humans; Lentivirus; Lipid Peroxidation; Lipoproteins; Mutation; Replicon; RNA, Viral; Serum; Trans-Activators; Transduction, Genetic; Virus Replication; Vitamin E	2015
Docetaxel (DTX)-loaded polydopamine-modified TPGS-PLA nanoparticles as a targeted drug delivery system for the treatment of liver cancer. Acta biomaterialia, 2016, Volume: 30 Topics: Animals; Carcinoma, Hepatocellular; Docetaxel; Drug Delivery Systems; Hep G2 Cells; Humans; Indoles; Lactic Acid; Liver Neoplasms, Experimental; Mice; Mice, Nude; Nanoparticles; Polyesters; Polyethylene Glycols; Polymers; Taxoids; Vitamin E; Xenograft Model Antitumor Assays	2016
δ and γ tocotrienols suppress human hepatocellular carcinoma cell proliferation via regulation of Ras-Raf-MEK-ERK pathway-associated upstream signaling. Food & function, 2016, Oct-12, Volume: 7, Issue:10 Topics: Carcinoma, Hepatocellular; Cell Proliferation; Chromans; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Liver Neoplasms; MAP Kinase Kinase Kinases; raf Kinases; ras Proteins; Signal Transduction; Vitamin E	2016
Coenzyme Q10 and Oxidative Stress: Inflammation Status in Hepatocellular Carcinoma Patients after Surgery. Nutrients, 2017, Jan-04, Volume: 9, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Aspartate Aminotransferases; Blood Glucose; C-Reactive Protein; Carcinoma, Hepatocellular; Creatinine; Glutathione Peroxidase; Humans; Inflammation; Interleukin-6; Linear Models; Liver Neoplasms; Malondialdehyde; Middle Aged; Oxidative Stress; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Tumor Necrosis Factor-alpha; Ubiquinone; Vitamin E; Young Adult	2017
Evaluation of redox statuses in patients with hepatitis B virus-associated hepatocellular carcinoma. Annals of clinical biochemistry, 2009, Volume: 46, Issue:Pt 5 Topics: Adult; Aged; Aged, 80 and over; Ascorbic Acid; Carcinoma, Hepatocellular; Female; Glutathione; Glutathione Disulfide; Glutathione Peroxidase; Glutathione Reductase; Hepatitis B; Hepatitis B virus; Humans; Liver Neoplasms; Male; Malondialdehyde; Middle Aged; Oxidation-Reduction; Superoxide Dismutase; Vitamin A; Vitamin E	2009
Gamma delta tocotrienols reduce hepatic triglyceride synthesis and VLDL secretion. Journal of atherosclerosis and thrombosis, 2010, Oct-27, Volume: 17, Issue:10 Topics: Animals; Apolipoprotein B-100; Blotting, Western; Carcinoma, Hepatocellular; Cell Proliferation; Cells, Cultured; Chromans; Diacylglycerol O-Acyltransferase; Female; Humans; Hydroxymethylglutaryl CoA Reductases; Lipoproteins, VLDL; Liver; Liver Neoplasms; Male; Mice; Mice, Knockout; Receptors, LDL; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sterol Regulatory Element Binding Protein 1; Sterol Regulatory Element Binding Protein 2; Triglycerides; Vitamin E	2010
γ-Tocotrienol is a novel inhibitor of constitutive and inducible STAT3 signalling pathway in human hepatocellular carcinoma: potential role as an antiproliferative, pro-apoptotic and chemosensitizing agent. British journal of pharmacology, 2011, Volume: 163, Issue:2 Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Chromans; Doxorubicin; Drug Resistance, Neoplasm; Drug Synergism; Enzyme Activation; Enzyme Induction; Genes, Reporter; Humans; Janus Kinases; Liver Neoplasms; NF-kappa B; Paclitaxel; Phosphorylation; Protein Kinase Inhibitors; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins c-akt; Signal Transduction; src-Family Kinases; STAT3 Transcription Factor; Vitamin E	2011
Relationships between blood levels of fat soluble vitamins and disease etiology and severity in adults awaiting liver transplantation. Journal of gastroenterology and hepatology, 2011, Volume: 26, Issue:9 Topics: Adolescent; Adult; Avitaminosis; Biomarkers; Calcifediol; Carcinoma, Hepatocellular; Cholestasis; Cross-Sectional Studies; End Stage Liver Disease; Female; Humans; Least-Squares Analysis; Liver Neoplasms; Liver Transplantation; Male; Middle Aged; Nutritional Status; Prospective Studies; Queensland; Regression Analysis; Risk Assessment; Risk Factors; Severity of Illness Index; Solubility; Vitamin A; Vitamin E; Vitamins; Waiting Lists; Young Adult	2011
Formulation, antileukemia mechanism, pharmacokinetics, and biodistribution of a novel liposomal emodin. International journal of nanomedicine, 2012, Volume: 7 Topics: Animals; Antineoplastic Agents; Blotting, Western; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Emodin; Female; Humans; Leukemia L1210; Liposomes; Liver Neoplasms; Male; Mice; Mice, Inbred ICR; Particle Size; Phosphatidylethanolamines; Polyethylene Glycols; Random Allocation; Tissue Distribution; Transferrin; Vitamin E	2012
Acquired tolerance of hepatocellular carcinoma cells to selenium deficiency: a selective survival mechanism? Cancer research, 2003, Oct-15, Volume: 63, Issue:20 Topics: Adaptation, Physiological; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Genome, Viral; Hepatitis B virus; Humans; Liver Neoplasms; Oxidative Stress; Selenium; Vitamin E	2003
Vitamin E protects DNA from oxidative damage in human hepatocellular carcinoma cell lines. Free radical research, 2004, Volume: 38, Issue:7 Topics: 8-Hydroxy-2'-Deoxyguanosine; Adenosine Diphosphate; Carcinoma, Hepatocellular; Cell Line, Tumor; Deoxyguanosine; DNA Damage; Humans; Oxidative Stress; Radiation, Ionizing; Thiobarbituric Acid Reactive Substances; Tocopherols; Tumor Stem Cell Assay; Vitamin E	2004
Intracellular trafficking of vitamin E in hepatocytes: the role of tocopherol transfer protein. Journal of lipid research, 2005, Volume: 46, Issue:10 Topics: Animals; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Carcinoma, Hepatocellular; Carrier Proteins; Cell Line, Tumor; Doxycycline; Glyburide; Hepatocytes; Humans; Microscopy, Confocal; Microscopy, Fluorescence; Rats; Vitamin E	2005
Effects of antioxidants and caspase-3 inhibitor on the phenylethyl isothiocyanate-induced apoptotic signaling pathways in human PLC/PRF/5 cells. European journal of pharmacology, 2005, Aug-22, Volume: 518, Issue:2-3 Topics: Acetylcysteine; Antioxidants; Apoptosis; Apoptosis Regulatory Proteins; Apoptotic Protease-Activating Factor 1; bcl-2-Associated X Protein; BH3 Interacting Domain Death Agonist Protein; Blotting, Western; Carcinoma, Hepatocellular; Carrier Proteins; Caspase 3; Caspase 8; Caspase 9; Caspase Inhibitors; Caspases; Cell Line, Tumor; Cell Proliferation; Cysteine Proteinase Inhibitors; Cytochromes c; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Activation; fas Receptor; Flow Cytometry; Humans; Intracellular Membranes; Intracellular Signaling Peptides and Proteins; Isothiocyanates; Liver Neoplasms; Membrane Potentials; Mitochondria; Mitochondrial Proteins; Oligopeptides; Proteins; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Time Factors; Tumor Suppressor Protein p53; Up-Regulation; Vitamin E; X-Linked Inhibitor of Apoptosis Protein	2005
Apoptosis induction by gamma-tocotrienol in human hepatoma Hep3B cells. The Journal of nutritional biochemistry, 2006, Volume: 17, Issue:10 Topics: Apoptosis; Carcinoma, Hepatocellular; Caspase 3; Caspase 8; Caspase 9; Caspases; Cell Division; Cell Line, Tumor; Chromans; Gene Expression; Genes, bcl-2; Humans; Liver Neoplasms; Poly(ADP-ribose) Polymerases; Tocotrienols; Vitamin E	2006
Hepatocellular carcinoma with peritoneal dissemination which was regressed during vitamin K2 and vitamin E administration. Internal medicine (Tokyo, Japan), 2007, Volume: 46, Issue:11 Topics: Aged; Apoptosis; Carcinoma, Hepatocellular; Combined Modality Therapy; Drug Therapy, Combination; Embolization, Therapeutic; Humans; Liver Neoplasms; Male; Neoplasm Seeding; Peritoneal Neoplasms; Rupture, Spontaneous; Vitamin E; Vitamin K 2; Vitamins	2007
[The role of alpha-tocopherol and retinol in correcting disorders of lipid peroxidation in patients with malignant liver neoplasms]. Voprosy onkologii, 1995, Volume: 41, Issue:1 Topics: Adenoma, Bile Duct; Carcinoma, Hepatocellular; Combined Modality Therapy; Humans; Lipid Peroxidation; Liver Neoplasms; Postoperative Complications; Vitamin A; Vitamin E	1995
Decreased activity of scavenger enzymes in human hepatocellular carcinoma, but not in liver metastases. International journal of clinical & laboratory research, 1994, Volume: 24, Issue:2 Topics: Adult; Aged; Carcinoma, Hepatocellular; Chromatography, High Pressure Liquid; Female; Glutathione Peroxidase; Humans; Liver; Liver Neoplasms; Male; Middle Aged; Selenium; Superoxide Dismutase; Vitamin A; Vitamin E	1994
Bromobenzene detoxification in the human liver-derived HepG2 cell line. Xenobiotica; the fate of foreign compounds in biological systems, 1994, Volume: 24, Issue:3 Topics: Antipain; Bromobenzenes; Carcinoma, Hepatocellular; Cell Survival; Culture Media; Cytochrome P-450 Enzyme System; Epoxide Hydrolases; Free Radicals; Glutathione; Humans; Inactivation, Metabolic; Lipid Peroxidation; Liver; Liver Neoplasms; Models, Biological; Prostaglandin-Endoperoxide Synthases; Tumor Cells, Cultured; Vitamin E	1994
Vitamin A, Vitamin E or beta-carotene status and hepatitis B-related hepatocellular carcinoma. Annals of epidemiology, 1993, Volume: 3, Issue:3 Topics: Adult; beta Carotene; Carcinoma, Hepatocellular; Carotenoids; Case-Control Studies; Diet; Hepatitis B; Humans; Liver Neoplasms; Male; Middle Aged; Odds Ratio; Risk Factors; Socioeconomic Factors; Vitamin A; Vitamin E	1993
Tocotrienols regulate cholesterol production in mammalian cells by post-transcriptional suppression of 3-hydroxy-3-methylglutaryl-coenzyme A reductase. The Journal of biological chemistry, 1993, May-25, Volume: 268, Issue:15 Topics: Acetates; Acetic Acid; Androstenes; Animals; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Line; Chickens; CHO Cells; Cholesterol; Chromans; Cricetinae; Gene Expression Regulation, Enzymologic; Humans; Hydroxycholesterols; Hydroxymethylglutaryl CoA Reductases; Ketoconazole; Kinetics; Liver Neoplasms; Liver Neoplasms, Experimental; Lovastatin; Mevalonic Acid; Rats; RNA Processing, Post-Transcriptional; RNA, Messenger; Suppression, Genetic; Tritium; Tumor Cells, Cultured; Vitamin E	1993
Alpha-tocopherol protects against a reduction in adenosylcobalamin in oxidatively stressed human cells. The Journal of nutrition, 1993, Volume: 123, Issue:7 Topics: Carcinoma, Hepatocellular; Cells, Cultured; Cobamides; Fibroblasts; Humans; Linoleic Acid; Linoleic Acids; Lipid Peroxidation; Liver Neoplasms; Oxidation-Reduction; Tumor Cells, Cultured; Vitamin E	1993
Effects of various fatty acids alone or combined with vitamin E on cell growth and fibrinogen concentration in the medium of HepG2 cells. Thrombosis research, 1995, Oct-01, Volume: 80, Issue:1 Topics: Carcinoma, Hepatocellular; Cell Division; Fatty Acids; Fibrinogen; Humans; Liver; Tumor Cells, Cultured; Vitamin E	1995
High-density lipoprotein 3 physicochemical modifications induced by interaction with human polymorphonuclear leucocytes affect their ability to remove cholesterol from cells. The Biochemical journal, 1996, Feb-15, Volume: 314 ( Pt 1) Topics: Animals; Apolipoproteins; Carcinoma, Hepatocellular; Cell Line; Cell Membrane; Cholesterol; Copper; Electrophoresis, Polyacrylamide Gel; Humans; Isoelectric Focusing; Kinetics; Lipoproteins, HDL; Macrophages; Membrane Lipids; Mice; Neutrophils; Particle Size; Rats; Tumor Cells, Cultured; Vitamin E	1996
Assay of free-radical toxicity and antioxidant effect on the Hep 3B cell line: a test survey using lindane. Cell biology and toxicology, 1996, Volume: 12, Issue:1 Topics: Antioxidants; Carcinoma, Hepatocellular; Free Radicals; Hexachlorocyclohexane; Humans; Liver; Oxidation-Reduction; Superoxide Dismutase; Tumor Cells, Cultured; Vitamin E	1996
Rapid loss in the mitochondrial membrane potential during geranylgeranoic acid-induced apoptosis. Biochemical and biophysical research communications, 1997, Jan-03, Volume: 230, Issue:1 Topics: Animals; Apoptosis; Carcinoma, Hepatocellular; Caspase 1; Cell Line; Cysteine Endopeptidases; Diterpenes; Fluorescent Dyes; Humans; Intracellular Membranes; Kinetics; Liver; Liver Neoplasms; Membrane Potentials; Mice; Mitochondria; Mitochondria, Liver; Rhodamine 123; Rhodamines; Time Factors; Tumor Cells, Cultured; Vitamin E	1997
Human lipoproteins as a vehicle for the delivery of beta-carotene and alpha-tocopherol to HepG2 cells. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1997, Volume: 214, Issue:4 Topics: Adult; beta Carotene; Carcinoma, Hepatocellular; Culture Media, Serum-Free; Drug Carriers; Humans; Lipoproteins; Liver; Liver Neoplasms; Male; Micelles; Middle Aged; Tumor Cells, Cultured; Vitamin E	1997
Correlation of repressed transcription of alpha-tocopherol transfer protein with serum alpha-tocopherol during hepatocarcinogenesis. International journal of cancer, 1997, May-16, Volume: 71, Issue:4 Topics: Aged; Animals; Carcinogens; Carcinoma, Hepatocellular; Carrier Proteins; Cholesterol; Diethylnitrosamine; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Humans; Hyperplasia; Liver; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Middle Aged; Neoplasm Proteins; Rats; Rats, Wistar; RNA, Messenger; RNA, Neoplasm; Transcription, Genetic; Vitamin A; Vitamin E; Vitamin E Deficiency	1997
Hepatic tocopherol content in primary hepatocellular carcinoma and liver metastases. Hepatology (Baltimore, Md.), 1997, Volume: 26, Issue:1 Topics: Aged; beta Carotene; Carcinoma, Hepatocellular; Carotenoids; Female; Humans; Lipids; Liver; Liver Neoplasms; Male; Middle Aged; Vitamin A; Vitamin E	1997
Antioxidative mechanism and apoptosis induction by 3-hydroxyanthranilic acid, an antioxidant in Indonesian food Tempeh, in the human hepatoma-derived cell line, HuH-7. Journal of nutritional science and vitaminology, 1997, Volume: 43, Issue:2 Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 3-Hydroxyanthranilic Acid; Animals; Antioxidants; Apoptosis; beta Carotene; Carcinoma, Hepatocellular; Female; Food; Glutathione; Glycine max; Humans; Indonesia; Mice; Mice, Inbred BALB C; Oxidative Stress; Superoxide Dismutase; Tumor Cells, Cultured; Vitamin E	1997
Plasma ratio of ubiquinol and ubiquinone as a marker of oxidative stress. Molecular aspects of medicine, 1997, Volume: 18 Suppl Topics: Biomarkers; Carcinoma, Hepatocellular; Chromatography, High Pressure Liquid; Coenzymes; Electrochemistry; Hepatitis; Hexanes; Humans; Liver Cirrhosis; Liver Diseases; Liver Neoplasms; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Solvents; Ubiquinone; Vitamin E	1997
Vitamins C, E and A and heme oxygenase in rats fed methyl/folate-deficient diets. Free radical biology & medicine, 1997, Volume: 23, Issue:6 Topics: Animals; Ascorbic Acid; Carcinoma, Hepatocellular; Choline Deficiency; Folic Acid Deficiency; Heme Oxygenase (Decyclizing); Liver Neoplasms; Male; Methionine; Niacin; Oxidative Stress; Rats; Rats, Inbred F344; Vitamin A; Vitamin E; Vitamin E Deficiency; Vitamins; Weight Gain	1997
Enhancing effect of thoraco-laparotomy on liver metastasis and the role played by active oxygens in its mechanism. Surgery today, 1997, Volume: 27, Issue:11 Topics: Animals; Antioxidants; Ascorbic Acid; Carcinoma, Hepatocellular; Free Radical Scavengers; Laparotomy; Lipid Peroxides; Liver Neoplasms; Male; Mice; Neoplasm Metastasis; Oxidative Stress; Rats; Rats, Inbred Strains; Tumor Cells, Cultured; Vitamin E	1997
High-density lipoprotein (HDL3)-associated alpha-tocopherol is taken up by HepG2 cells via the selective uptake pathway and resecreted with endogenously synthesized apo-lipoprotein B-rich lipoprotein particles. The Biochemical journal, 1998, May-15, Volume: 332 ( Pt 1) Topics: Acrylamide; Acrylamides; Adenosine Triphosphatases; Apolipoproteins B; Carcinoma, Hepatocellular; Cholesterol; Colchicine; Enzyme Inhibitors; Humans; Lipoproteins, HDL; Lipoproteins, LDL; Monensin; Tumor Cells, Cultured; Vitamin E	1998
Oxidative stress in patients with hepatitis, cirrhosis, and hepatoma evaluated by plasma antioxidants. Biochemical and biophysical research communications, 1998, Jun-09, Volume: 247, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Antioxidants; Ascorbic Acid; beta Carotene; Biomarkers; Carcinoma, Hepatocellular; Carotenoids; Cholesterol; Cholesterol Esters; Female; Hepatitis, Chronic; Humans; Liver Cirrhosis; Liver Diseases; Liver Neoplasms; Lycopene; Male; Middle Aged; Oxidative Stress; Ubiquinone; Vitamin E	1998
Growth modulating effects of chlorinated oleic acid in cell cultures. Pharmacology & toxicology, 1998, Volume: 83, Issue:1 Topics: Albumins; Animals; Carcinoma, Hepatocellular; Cell Count; Cell Division; Cell Line; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Endothelium, Vascular; Epithelial Cells; Humans; Kidney; Liver Neoplasms; Stearic Acids; Vitamin E	1998
Cytoprotection against lipid hydroperoxides correlates with increased glutathione peroxidase activities, but not selenium uptake from different selenocompounds. Biological trace element research, 1999, Volume: 68, Issue:2 Topics: Antioxidants; Biological Availability; Carcinoma, Hepatocellular; Cytoprotection; Dose-Response Relationship, Drug; Glutathione Peroxidase; Humans; Lipid Peroxides; Selenium; Time Factors; Tumor Cells, Cultured; Vitamin E	1999
Plasma ubiquinone to ubiquinol ratio in patients with hepatitis, cirrhosis, and hepatoma, and in patients treated with percutaneous transluminal coronary reperfusion. BioFactors (Oxford, England), 1999, Volume: 9, Issue:2-4 Topics: Adult; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Ascorbic Acid; beta Carotene; Bilirubin; Biomarkers; Carcinoma, Hepatocellular; Carotenoids; Female; Hepatitis; Humans; Liver Cirrhosis; Liver Neoplasms; Lycopene; Male; Middle Aged; Oxidative Stress; Reference Values; Ubiquinone; Uric Acid; Vitamin E	1999
Semecarpus anacardium L. nut extract administration induces the in vivo antioxidant defence system in aflatoxin B1 mediated hepatocellular carcinoma. Journal of ethnopharmacology, 1999, Volume: 66, Issue:2 Topics: Aflatoxin B1; Animals; Antioxidants; Ascorbic Acid; Carcinogens; Carcinoma, Hepatocellular; Cytochrome P-450 Enzyme System; India; Liver Neoplasms, Experimental; Male; Nuts; Plant Extracts; Plants, Medicinal; Rats; Rats, Wistar; Uric Acid; Vitamin E	1999
Effects of dietary iron overload on progression in chemical hepatocarcinogenesis. Liver, 1999, Volume: 19, Issue:4 Topics: 2-Acetylaminofluorene; Animals; Apoptosis; Carcinogens; Carcinoma, Hepatocellular; Cell Division; Chromatography, High Pressure Liquid; Diethylnitrosamine; Disease Progression; Glutathione Transferase; Hemochromatosis; Iron; Iron, Dietary; Liver; Liver Neoplasms, Experimental; Male; Oxidative Stress; Rats; Rats, Wistar; Ubiquinone; Vitamin E	1999
Induction of catalase, alpha, and microsomal glutathione S-transferase in CYP2E1 overexpressing HepG2 cells and protection against short-term oxidative stress. Hepatology (Baltimore, Md.), 2001, Volume: 33, Issue:3 Topics: Aldehydes; Carcinoma, Hepatocellular; Catalase; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Enzyme Induction; Extracellular Space; Glutathione Transferase; Humans; Hydrogen Peroxide; Isoenzymes; Liver Neoplasms; Microsomes, Liver; Mixed Function Oxygenases; Oxidants; Oxidative Stress; RNA, Messenger; Tumor Cells, Cultured; Vitamin E	2001
Effects of ascorbic acid and DL-alpha-tocopherol on human hepatoma cell proliferation and redifferentiation. Acta pharmacologica Sinica, 2000, Volume: 21, Issue:4 Topics: alpha-Fetoproteins; Ascorbic Acid; Carcinoma, Hepatocellular; Cell Differentiation; Cell Division; gamma-Glutamyltransferase; Humans; Liver Neoplasms; Tumor Cells, Cultured; Vitamin E	2000
Decreased disappearance rate of 1-(2-tetrahydrofuryl)-5-fluorouracil (FT-207) from the blood and its unresponsiveness to tocophreyl nicotinate and indomethacin in patients with primary hepatocellular carcinoma. Acta medica Okayama, 1979, Volume: 33, Issue:5 Topics: Carcinoma, Hepatocellular; Fluorouracil; Humans; Indomethacin; Kinetics; Liver Cirrhosis; Liver Neoplasms; Microsomes, Liver; Nicotinic Acids; Tegafur; Vitamin E	1979
Growth inhibition of human hepatoma cells (HepG2) by polyunsaturated fatty acids. Protection by albumin and vitamin E. Acta physiologica Scandinavica, 1992, Volume: 144, Issue:1 Topics: Albumins; Carcinoma, Hepatocellular; Cell Division; Fatty Acids, Unsaturated; Humans; In Vitro Techniques; Lipoproteins, VLDL; Liver Neoplasms; Tumor Cells, Cultured; Vitamin E	1992
Levels of vitamin A and cellular retinol binding protein in human hepatocellular carcinoma and adjacent normal tissue. Nutrition and cancer, 1989, Volume: 12, Issue:4 Topics: Adult; Aged; Carcinoma, Hepatocellular; Female; Humans; Liver; Liver Neoplasms; Male; Middle Aged; Prospective Studies; Retinol-Binding Proteins; Retinol-Binding Proteins, Cellular; Vitamin A; Vitamin E	1989
Vitamins E and K induce aryl hydrocarbon hydroxylase activity in human cell cultures. Biochemical and biophysical research communications, 1987, Mar-30, Volume: 143, Issue:3 Topics: Aryl Hydrocarbon Hydroxylases; Breast Neoplasms; Carcinoma, Hepatocellular; Cell Line; Enzyme Induction; Humans; Kinetics; Liver Neoplasms; Vitamin E; Vitamin K	1987
Biochemical, pathological, and genetic aspects of a spontaneous mouse hepatoma. Journal of the National Cancer Institute, 1969, Volume: 43, Issue:2 Topics: Age Factors; Animals; Carcinoma, Hepatocellular; Diet; Fatty Liver; Female; Hybridization, Genetic; Karyotyping; L-Serine Dehydratase; Liver; Liver Neoplasms; Male; Methylation; Mice; Neoplasms, Experimental; Rats; RNA, Transfer; Sex Factors; Transaminases; Transferases; Vitamin E	1969