Page last updated: 2024-08-21

d-alpha tocopherol and Amyotrophic Lateral Sclerosis

d-alpha tocopherol has been researched along with Amyotrophic Lateral Sclerosis in 36 studies

Research

Studies (36)

Timeframe	Studies, this research(%)	All Research%
pre-1990	4 (11.11)	18.7374
1990's	15 (41.67)	18.2507
2000's	10 (27.78)	29.6817
2010's	5 (13.89)	24.3611
2020's	2 (5.56)	2.80

Authors

Authors	Studies
Richard, B	1
Arslan, N; Gezmen-Karadag, M; Icer, MA	1
Ewing, AG; Hanrieder, J	1
Inaba, Y; Kihira, T; Kobashi, G; Miyake, Y; Nagai, M; Okamoto, K; Sakamoto, N; Sasaki, S; Washio, M; Yokoyama, T	1
Ascherio, A; Kolonel, LN; Logroscino, G; McCullough, ML; O'Reilly, ÉJ; Schatzkin, A; Wang, H; Weisskopf, MG	1
Indo, HP; Majima, HJ; Matsui, H; Ozawa, T; Suenaga, S; Yen, HC	1
Carothers, S; Chang, Y; Glenn Lin, CL; Kong, Q	1
Albanes, D; Kuncl, RW; Malila, N; Michal Freedman, D; Virtamo, J; Weinstein, SJ	1
Butterfield, DA; Calabrese, V; Castegna, A; Drake, J; Scapagnini, G	1
Becker, G; Dengler, R; Ecker, D; Eger, K; Gerlach, M; Graf, M; Hager, C; Hecht, M; Hoge, A; Horowski, R; Jost, WH; Kostopulos, P; Kramer, B; Krampfl, K; Lubik, S; Ludolph, AC; Neudecker, S; Neundörfer, B; Osterhage, J; Petri, S; Riederer, P; Schimke, N; Schrader, C; Schrank, B; Sievert, M; Stein, C; Traufeller, K; Troeger, M; Wekwerth, K; Wuerz, A; Zierz, S	1
Ascherio, A; Calle, EE; Cudkowicz, M; Jacobs, EJ; McCullough, ML; O'reilly, EJ; Thun, MJ; Weisskopf, MG	1
Appollonio, I; Facheris, M; Ferrarese, C; Galbusera, C; Galimberti, G; Galli-Kienle, M; Guerini, FR; Isella, V; Magni, F; Sala, G; Tremolada, L	1
de Vries, JH; Groeneveld, GJ; Kalmijn, S; Koster, A; Van den Berg, LH; van der Luyt, J; Veldink, JH; Wokke, JH; Wunderink, W	1
Brighina, L; Cavaletti, G; Ferrarese, C; Filippini, G; Galbussera, A; Lovati, R; Testa, D; Tremolizzo, L	1
Bach, A; Bähr, M; Bartels, C; Bohn, M; Dietrich, J; Ehrenreich, H; Hardeland, R; Hüther, G; Mertens, N; Nave, KA; Poeggeler, B; Pölking, E; Rohde, G; Schneider, A; Sirén, AL; Sperling, S; Weishaupt, JH	1
Graf, M; Groeneveld, GJ; Ludolph, AC; van den Berg, LH; van der Tweel, I	1
Ikeda, K; Iwasaki, Y; Kinoshita, M	1
Marx, J	1
Abe, T; Saheki, M; Takahashi, S; Tohgi, H; Yamazaki, K	1
Andrus, PK; Cutting, FB; Gurney, ME; Hall, ED; Zhai, P	1
Keane, JR	1
Hugon, J; Lesort, M; Ludolph, A; Terro, F; Viader, F	1
Andrus, PK; Cutting, FB; Doble, A; Gurney, ME; Hall, ED; Taylor, CP; Zhai, P	1
Carrasquedo, F; Dubrovski, AL; Fraga, CG; Oteiza, PI; Roma, JC; Uchitel, OD	1
Paulson, GW; Reider, CR	1
Gurney, ME	1
Andrus, PK; Fleck, TJ; Gurney, ME; Hall, ED; Oostveen, JA	1
de Jong, JM; Guchelaar, HJ; Haasdijk, E; Holstege, JC; Jaarsma, D	1
Apostolski, S; Blagojević, D; Marinković, Z; Michelson, AM; Nikolić, A; Spasić, MB	1
Pascuzzi, RM	1
Arenas, J; de Bustos, F; Enríquez de Salamanca, R; Esteban, J; Gómez-Escalonilla, C; Guerrero-Sola, A; Jiménez-Jiménez, FJ; Molina, JA; Ortí-Pareja, M; Ramírez-Ramos, C; Tallón-Barranco, A; Zurdo, M	1
Jamrozik, Z; Janik, P; Kwieciński, H; Opuchlik, A	1
Denys, EH; Norris, FH	1
Domzal, T; Ilnicki, S	1
Dorman, JD; Engel, WK; Fried, DM	1

Reviews

4 review(s) available for d-alpha tocopherol and Amyotrophic Lateral Sclerosis

Article	Year
Effects of vitamin E on neurodegenerative diseases: an update. Acta neurobiologiae experimentalis, 2021, Volume: 81, Issue:1 Topics: Alzheimer Disease; Amyotrophic Lateral Sclerosis; Animals; Humans; Neurodegenerative Diseases; Parkinson Disease; Stroke; Vitamin E	2021
Mitochondria as possible pharmaceutical targets for the effects of vitamin E and its homologues in oxidative stress-related diseases. Current pharmaceutical design, 2011, Volume: 17, Issue:21 Topics: Aging; Amyotrophic Lateral Sclerosis; Animals; Humans; Mitochondria; Neoplasms; Oxidative Stress; Superoxide Dismutase; Vitamin E	2011
Vitamin E and neurodegenerative disorders associated with oxidative stress. Nutritional neuroscience, 2002, Volume: 5, Issue:4 Topics: Alzheimer Disease; Amyotrophic Lateral Sclerosis; Biological Availability; Dyskinesias; Humans; Huntington Disease; Intestinal Absorption; Lipid Peroxidation; Multiple Sclerosis; Neurodegenerative Diseases; Oxidative Stress; Parkinson Disease; Vitamin E	2002
Pathogenic mechanisms in familial amyotrophic lateral sclerosis due to mutation of Cu, Zn superoxide dismutase. Pathologie-biologie, 1996, Volume: 44, Issue:1 Topics: Amyotrophic Lateral Sclerosis; Animals; Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human, Pair 21; Excitatory Amino Acid Antagonists; Humans; Mice; Mice, Transgenic; Mutation; Riluzole; Superoxide Dismutase; Thiazoles; Vitamin E	1996

Trials

9 trial(s) available for d-alpha tocopherol and Amyotrophic Lateral Sclerosis

Article	Year
Vitamin E serum levels and controlled supplementation and risk of amyotrophic lateral sclerosis. Amyotrophic lateral sclerosis & frontotemporal degeneration, 2013, Volume: 14, Issue:4 Topics: Aged; Amyotrophic Lateral Sclerosis; Cohort Studies; Dietary Supplements; Double-Blind Method; Follow-Up Studies; Humans; Male; Middle Aged; Prospective Studies; Risk Factors; Vitamin E	2013
High dose vitamin E therapy in amyotrophic lateral sclerosis as add-on therapy to riluzole: results of a placebo-controlled double-blind study. Journal of neural transmission (Vienna, Austria : 1996), 2005, Volume: 112, Issue:5 Topics: Amyotrophic Lateral Sclerosis; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Neuroprotective Agents; Riluzole; Treatment Outcome; Vitamin E; Vitamins	2005
Vitamin E intake and risk of amyotrophic lateral sclerosis. Annals of neurology, 2005, Volume: 57, Issue:1 Topics: Adult; Age Factors; Aged; Amyotrophic Lateral Sclerosis; Antioxidants; Ascorbic Acid; Cohort Studies; Confidence Intervals; Cross-Sectional Studies; Dietary Supplements; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Male; Prospective Studies; Retrospective Studies; Risk; Risk Factors; Sex Factors; Surveys and Questionnaires; Vitamin E; Vitamins	2005
Reduced oxidative damage in ALS by high-dose enteral melatonin treatment. Journal of pineal research, 2006, Volume: 41, Issue:4 Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Animals; Biomarkers; Cell Line; Cytoprotection; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Glutamic Acid; Humans; Male; Melatonin; Mice; Mice, Transgenic; Middle Aged; Neurons; Oxidative Stress; Reactive Oxygen Species; Superoxide Dismutase; Superoxide Dismutase-1; Survival Rate; Vitamin E	2006
Alternative trial design in amyotrophic lateral sclerosis saves time and patients. Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases, 2007, Volume: 8, Issue:5 Topics: Amyotrophic Lateral Sclerosis; Clinical Trials as Topic; Confidence Intervals; Double-Blind Method; Humans; Odds Ratio; Research Design; Retrospective Studies; Sample Size; Survival Analysis; Time Factors; Vitamin E	2007
Vitamin A and E levels are normal in amyotrophic lateral sclerosis. Journal of the neurological sciences, 1995, Volume: 132, Issue:2 Topics: Aged; Amyotrophic Lateral Sclerosis; Chromatography, High Pressure Liquid; Female; Humans; Male; Vitamin A; Vitamin E	1995
Glutathione peroxidase in amyotrophic lateral sclerosis: the effects of selenium supplementation. Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 1998, Volume: 17, Issue:3-4 Topics: Adult; Aged; Amino Acids; Amyotrophic Lateral Sclerosis; beta Carotene; Calcium Channel Blockers; Catalase; Dietary Supplements; Double-Blind Method; Erythrocytes; Female; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Humans; Male; Middle Aged; Nimodipine; Selenium; Superoxide Dismutase; Vitamin E	1998
[The effect of selegiline and vitamin E in the treatment of ALS: an open randomized clinical trials]. Neurologia i neurochirurgia polska, 2001, Volume: 35, Issue:1 Suppl Topics: Adolescent; Adult; Aged; Amyotrophic Lateral Sclerosis; Female; Follow-Up Studies; Humans; Male; Middle Aged; Neuroprotective Agents; Selegiline; Survival Rate; Vitamin E	2001
Nutritional supplements in amyotrophic lateral sclerosis. Advances in experimental medicine and biology, 1987, Volume: 209 Topics: Administration, Oral; Adult; Amyotrophic Lateral Sclerosis; Cachexia; Clinical Trials as Topic; Double-Blind Method; Fat Necrosis; Fatty Alcohols; Female; Humans; Injections, Intramuscular; Male; Middle Aged; Patient Compliance; Random Allocation; Vitamin E	1987

Other Studies

23 other study(ies) available for d-alpha tocopherol and Amyotrophic Lateral Sclerosis

Article	Year
ALSUntangled 55: vitamin E (α-tocopherol). Amyotrophic lateral sclerosis & frontotemporal degeneration, 2021, Volume: 22, Issue:1-2 Topics: Amyotrophic Lateral Sclerosis; Antioxidants; Dietary Supplements; Humans; Tocopherols; Vitamin E	2021
Spatial elucidation of spinal cord lipid- and metabolite- regulations in amyotrophic lateral sclerosis. Scientific reports, 2014, Jun-12, Volume: 4 Topics: Amyotrophic Lateral Sclerosis; Anterior Horn Cells; Case-Control Studies; Cell Death; Cholesterol; Humans; Lipids; Lysophosphatidylcholines; Motor Neuron Disease; Motor Neurons; Nerve Degeneration; Spectrometry, Mass, Secondary Ion; Spinal Cord; Triglycerides; Vitamin E	2014
Fruit and vegetable intake and risk of amyotrophic lateral sclerosis in Japan. Neuroepidemiology, 2009, Volume: 32, Issue:4 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amyotrophic Lateral Sclerosis; Antioxidants; Ascorbic Acid; beta Carotene; Diet; Female; Fruit; Humans; Japan; Male; Middle Aged; Surveys and Questionnaires; Vegetables; Vitamin E; Young Adult	2009
Vitamin E intake and risk of amyotrophic lateral sclerosis: a pooled analysis of data from 5 prospective cohort studies. American journal of epidemiology, 2011, Mar-15, Volume: 173, Issue:6 Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Antioxidants; Diet; Dietary Supplements; Female; Humans; Male; Middle Aged; Proportional Hazards Models; Prospective Studies; Risk Factors; Surveys and Questionnaires; Vitamin E; Vitamin E Deficiency	2011
The importance of preclinical trial timing - a potential reason for the disconnect between mouse studies and human clinical trials in ALS. CNS neuroscience & therapeutics, 2012, Volume: 18, Issue:9 Topics: Amyotrophic Lateral Sclerosis; Animals; Anti-Bacterial Agents; Antioxidants; Ceftriaxone; Disease Models, Animal; Disease Progression; Drug Evaluation, Preclinical; Drug Therapy, Combination; Humans; Mice; Mice, Transgenic; Minocycline; Research Design; Superoxide Dismutase; Treatment Outcome; Vitamin E	2012
Increased susceptibility to plasma lipid peroxidation in Alzheimer disease patients. Current Alzheimer research, 2004, Volume: 1, Issue:2 Topics: Aged; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Antioxidants; Apolipoproteins E; Ascorbic Acid; Case-Control Studies; Copper; Female; Humans; Lipid Peroxidation; Male; Middle Aged; Oxidation-Reduction; Polymorphism, Genetic; Severity of Illness Index; Thiobarbituric Acid Reactive Substances; Vitamin E	2004
Intake of polyunsaturated fatty acids and vitamin E reduces the risk of developing amyotrophic lateral sclerosis. Journal of neurology, neurosurgery, and psychiatry, 2007, Volume: 78, Issue:4 Topics: Adult; Aged; Aged, 80 and over; Amyotrophic Lateral Sclerosis; Body Mass Index; Case-Control Studies; Dietary Fats, Unsaturated; Fatty Acids, Unsaturated; Female; Humans; Male; Middle Aged; Odds Ratio; Regression Analysis; Risk Assessment; Risk Factors; Vitamin E	2007
Vitamin E intake and quality of life in amyotrophic lateral sclerosis patients: a follow-up case series study. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2006, Volume: 27, Issue:3 Topics: Aged; Aged, 80 and over; Amyotrophic Lateral Sclerosis; Dietary Supplements; Female; Follow-Up Studies; Health Surveys; Humans; Male; Middle Aged; Neuroprotective Agents; Quality of Life; Riluzole; Vitamin E; Vitamins	2006
Mutant enzyme provides new insights into the cause of ALS. Science (New York, N.Y.), 1996, Jan-26, Volume: 271, Issue:5248 Topics: Amyotrophic Lateral Sclerosis; Animals; Apoptosis; Cells, Cultured; Free Radicals; Humans; Lipid Peroxidation; Mice; Mutation; Neurons; Nitrates; Peroxidases; Selenium; Superoxide Dismutase; Vitamin E	1996
alpha-Tocopherol quinone level is remarkably low in the cerebrospinal fluid of patients with sporadic amyotrophic lateral sclerosis. Neuroscience letters, 1996, Mar-22, Volume: 207, Issue:1 Topics: Aged; Amyotrophic Lateral Sclerosis; Antioxidants; Humans; Lipid Peroxidation; Middle Aged; Vitamin E	1996
Amyotrophic lateral sclerosis and vitamin E. Annals of neurology, 1996, Volume: 40, Issue:3 Topics: Amyotrophic Lateral Sclerosis; Famous Persons; History, 20th Century; Humans; Male; United States; Vitamin E	1996
Antioxidant drugs block in vitro the neurotoxicity of CSF from patients with amyotrophic lateral sclerosis. Neuroreport, 1996, Aug-12, Volume: 7, Issue:12 Topics: Adult; Aged; Allopurinol; Amyotrophic Lateral Sclerosis; Antioxidants; Cerebrospinal Fluid; Female; Humans; In Vitro Techniques; Male; Middle Aged; Vitamin E	1996
Benefit of vitamin E, riluzole, and gabapentin in a transgenic model of familial amyotrophic lateral sclerosis. Annals of neurology, 1996, Volume: 39, Issue:2 Topics: Acetates; Amines; Amyotrophic Lateral Sclerosis; Animals; Brain; Cyclohexanecarboxylic Acids; Diet; Disease Progression; Gabapentin; gamma-Aminobutyric Acid; Humans; Mice; Mice, Transgenic; Oxidative Stress; Riluzole; Spinal Cord; Superoxide Dismutase; Survival Analysis; Thiazoles; Vitamin E	1996
Evaluation of antioxidants, protein, and lipid oxidation products in blood from sporadic amyotrophic lateral sclerosis patients. Neurochemical research, 1997, Volume: 22, Issue:4 Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Antioxidants; beta Carotene; Blood Proteins; Diet; Erythrocytes; Female; Humans; Lipid Peroxidation; Male; Middle Aged; Oxidative Stress; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Ubiquinone; Vitamin E	1997
Lou Gehrig and amyotrophic lateral sclerosis. Is vitamin E to be revisited? Archives of neurology, 1997, Volume: 54, Issue:5 Topics: Amyotrophic Lateral Sclerosis; Baseball; Famous Persons; History, 20th Century; Humans; United States; Vitamin E	1997
Transgenic animal models of familial amyotrophic lateral sclerosis. Journal of neurology, 1997, Volume: 244 Suppl 2 Topics: Amyotrophic Lateral Sclerosis; Animals; Disease Models, Animal; Food, Fortified; Mice; Mice, Transgenic; Point Mutation; Selenium; Superoxide Dismutase; Vitamin E	1997
Relationship of oxygen radical-induced lipid peroxidative damage to disease onset and progression in a transgenic model of familial ALS. Journal of neuroscience research, 1998, Jul-01, Volume: 53, Issue:1 Topics: Aging; Amyotrophic Lateral Sclerosis; Animals; Antioxidants; Chromatography, High Pressure Liquid; Disease Progression; Free Radicals; Immunohistochemistry; Lipid Peroxidation; Malondialdehyde; Mice; Mice, Transgenic; Motor Neurons; Paralysis; Spinal Cord; Vitamin E	1998
The antioxidant N-acetylcysteine does not delay disease onset and death in a transgenic mouse model of amyotrophic lateral sclerosis. Annals of neurology, 1998, Volume: 44, Issue:2 Topics: Acetylcysteine; Administration, Oral; Amyotrophic Lateral Sclerosis; Animals; Body Weight; Disease Progression; Free Radical Scavengers; Half-Life; Mice; Mice, Transgenic; Point Mutation; Vitamin E	1998
Blinded and seeing the light, (John Noseworthy), Lou Gehrig and other tales of enlightenment). Seminars in neurology, 1998, Volume: 18, Issue:3 Topics: Amyotrophic Lateral Sclerosis; Clinical Trials as Topic; Double-Blind Method; History, 20th Century; Humans; Male; Outcome Assessment, Health Care; Vitamin E	1998
Cerebrospinal fluid levels of alpha-tocopherol in amyotrophic lateral sclerosis. Journal of neural transmission (Vienna, Austria : 1996), 1998, Volume: 105, Issue:6-7 Topics: Aged; Amyotrophic Lateral Sclerosis; Female; Humans; Lumbosacral Region; Male; Middle Aged; Reference Values; Vitamin E	1998
[Palliative therapy in amyotrophic lateral sclerosis]. Der Landarzt, 1967, Apr-20, Volume: 43, Issue:11 Topics: Amino Acids; Amyotrophic Lateral Sclerosis; Atropa belladonna; Cytochromes; Humans; Massage; Palliative Care; Phytotherapy; Plants, Medicinal; Plants, Toxic; Vitamin E	1967
[Attempts at treatment of amyotrophic lateral sclerosis]. Wiadomosci lekarskie (Warsaw, Poland : 1960), 1974, Jun-01, Volume: 27, Issue:11 Topics: Administration, Oral; Adult; Aged; Amyotrophic Lateral Sclerosis; Drug Evaluation; Female; Humans; Male; Middle Aged; Quinones; Uracil Nucleotides; Vitamin E	1974
Therapeutic trial in amyotrophic lateral sclerosis. JAMA, 1969, Jul-14, Volume: 209, Issue:2 Topics: Amyotrophic Lateral Sclerosis; Diet Therapy; Dietary Proteins; Humans; Muscles; Pancreatic Extracts; Vitamin E	1969