d-ala(2)-mephe(4)-met(0)-ol-enkephalin has been researched along with Neoplasm-Metastasis* in 1 studies
1 other study(ies) available for d-ala(2)-mephe(4)-met(0)-ol-enkephalin and Neoplasm-Metastasis
Article | Year |
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The antimetastatic activity of enkephalin-like peptides.
[Met5]Enkephalin and [Leu5]enkephalin, two naturally occurring opioid-like peptides were found to decrease the number of spontaneous pulmonary metastases in C57BL/6J mice implanted in the foot pad with the B16-BL6 melanoma. The number of such metastatic nodules were reduced more than 2-fold. This effect was noted after several different injection schedules. In addition to their effect on metastasis the growth rate of the primary tumor was also decreased by these compounds. Topics: Animals; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Lung Neoplasms; Melanoma; Mice; Mice, Inbred C57BL; Neoplasm Metastasis | 1987 |