cytosine has been researched along with Rhabdomyosarcoma in 5 studies
Rhabdomyosarcoma: A malignant solid tumor arising from mesenchymal tissues which normally differentiate to form striated muscle. It can occur in a wide variety of sites. It is divided into four distinct types: pleomorphic, predominantly in male adults; alveolar (RHABDOMYOSARCOMA, ALVEOLAR), mainly in adolescents and young adults; embryonal (RHABDOMYOSARCOMA, EMBRYONAL), predominantly in infants and children; and botryoidal, also in young children. It is one of the most frequently occurring soft tissue sarcomas and the most common in children under 15. (From Dorland, 27th ed; Holland et al., Cancer Medicine, 3d ed, p2186; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, pp1647-9)
| Excerpt | Relevance | Reference |
|---|---|---|
| " In both human lung adenocarcinoma cells (HTB-54) and human rhabdomyosarcoma cells (CCl-136), pulse exposures to the topoisomerase II inhibitors etoposide and nalidixic acid; to the antibiotic doxorubicin; to the microtubule inhibitors vincristine, vinblastine, and colchicine; to the DNA cross-linking agent cisplatinum; to hydroxyurea; and to the antimetabolites 1-beta-D-arabinofuranosylcytosine, 5-fluorouracil, 5-fluorodeoxyuridine, and methotrexate were associated with profound drug-induced DNA hypermethylation." | 3.67 | Drug-induced DNA hypermethylation and drug resistance in human tumors. ( Nyce, J, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (60.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lam, W | 1 |
| Leung, CH | 1 |
| Bussom, S | 1 |
| Cheng, YC | 1 |
| Sutow, WW | 1 |
| Sullivan, MP | 1 |
| von Wronski, MA | 1 |
| Harris, LC | 1 |
| Tano, K | 1 |
| Mitra, S | 1 |
| Bigner, DD | 1 |
| Brent, TP | 1 |
| Nyce, J | 1 |
| Visser, GW | 1 |
| Boele, S | 1 |
| Knops, GH | 1 |
| Herscheid, JD | 1 |
| Hoekstra, A | 1 |
5 other studies available for cytosine and Rhabdomyosarcoma
| Article | Year |
|---|---|
The impact of hypoxic treatment on the expression of phosphoglycerate kinase and the cytotoxicity of troxacitabine and gemcitabine.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Carcinoma; Carcinoma, Hepatocellular; Cell H | 2007 |
Childhood cancer: the improving prognosis.
Topics: Asparaginase; Child; Cyclophosphamide; Cytosine; Daunorubicin; Doxorubicin; Drug Therapy, Combinatio | 1976 |
Cytosine methylation and suppression of O6-methylguanine-DNA methyltransferase expression in human rhabdomyosarcoma cell lines and xenografts.
Topics: Animals; Cell Line; Child; Cytosine; Gene Expression Regulation, Enzymologic; Gene Expression Regula | 1992 |
Drug-induced DNA hypermethylation and drug resistance in human tumors.
Topics: 5-Methylcytosine; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Line; Cell Survival; Cytosin | 1989 |
Synthesis and biodistribution of [18F]-5-fluorocytosine.
Topics: Animals; Cytosine; Flucytosine; Fluorine; Radioisotopes; Radionuclide Imaging; Rats; Rats, Inbred St | 1985 |