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cytosine and Retinitis

cytosine has been researched along with Retinitis in 19 studies

Retinitis: Inflammation of the RETINA. It is rarely limited to the retina, but is commonly associated with diseases of the choroid (CHORIORETINITIS) and of the OPTIC DISK (neuroretinitis).

Research Excerpts

ExcerptRelevanceReference
"Five AIDS patients with cytomegalovirus (CMV) retinitis who had received ganciclovir (GCV) therapy were followed with serial blood sampling to detectchanges both in CMV load and in the genetic composition of genes UL97 and UL54 whilst receiving cidofovir (CDV) therapy."7.70Quantitative changes in cytomegalovirus DNAemia and genetic analysis of the UL97 and UL54 genes in AIDS patients receiving cidofovir following ganciclovir therapy. ( Bowen, EF; Cherrington, JM; Emery, VC; Griffiths, PD; Johnson, MA; Lamy, PD, 1999)
"(S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (HPMPC), a high-potency antiherpes and anticytomegalovirus (CMV) drug was evaluated in the treatment of experimental retinitis caused by preretinal herpes simplex virus (HSV-1) injection in rabbits."7.69Long-acting therapy of viral retinitis with (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine. ( Bergeron-Lynn, G; Chandler, B; De Clercq, E; Flores-Aguilar, M; Freeman, WR; Huang, JS; Munguia, D; Vuong, C; Wiley, CA, 1994)
"The effect of liposome-encapsulated (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (HPMPC; cidofovir) was evaluated as prophylaxis in a rabbit model of experimentally induced retinitis caused by preretinal inoculation of herpes simplex virus type 1 (HSV-1)."7.69Liposome-encapsulated (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine for long-acting therapy of viral retinitis. ( Assil, KK; Bergeron-Lynn, G; Besen, G; Connor, JD; De Clercq, E; Freeman, WR; Kuppermann, BD; Munguia, D; Pursley, M; Vuong, C; Wiley, CA, 1996)
"Five AIDS patients with cytomegalovirus (CMV) retinitis who had received ganciclovir (GCV) therapy were followed with serial blood sampling to detectchanges both in CMV load and in the genetic composition of genes UL97 and UL54 whilst receiving cidofovir (CDV) therapy."3.70Quantitative changes in cytomegalovirus DNAemia and genetic analysis of the UL97 and UL54 genes in AIDS patients receiving cidofovir following ganciclovir therapy. ( Bowen, EF; Cherrington, JM; Emery, VC; Griffiths, PD; Johnson, MA; Lamy, PD, 1999)
"To evaluate(s)-1-(3-hydroxy-2-phosphonyl methoxypropyl) cytosine (HPMPC), a potent antiherpes and anticytomegalovirus drug, as a long-term treatment of experimental retinitis in rabbits."3.69Long-term therapy for herpes retinitis in an animal model with high-concentrated liposome-encapsulated HPMPC. ( Assil, KK; Bergeron-Lynn, G; Besen, G; De Clercq, E; Flores-Aguilar, M; Gangan, P; Kupperman, BD; Munguia, D; Pursley, M; Vuong, C, 1995)
"(S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (HPMPC), a high-potency antiherpes and anticytomegalovirus (CMV) drug was evaluated in the treatment of experimental retinitis caused by preretinal herpes simplex virus (HSV-1) injection in rabbits."3.69Long-acting therapy of viral retinitis with (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine. ( Bergeron-Lynn, G; Chandler, B; De Clercq, E; Flores-Aguilar, M; Freeman, WR; Huang, JS; Munguia, D; Vuong, C; Wiley, CA, 1994)
"The effect of liposome-encapsulated (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (HPMPC; cidofovir) was evaluated as prophylaxis in a rabbit model of experimentally induced retinitis caused by preretinal inoculation of herpes simplex virus type 1 (HSV-1)."3.69Liposome-encapsulated (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine for long-acting therapy of viral retinitis. ( Assil, KK; Bergeron-Lynn, G; Besen, G; Connor, JD; De Clercq, E; Freeman, WR; Kuppermann, BD; Munguia, D; Pursley, M; Vuong, C; Wiley, CA, 1996)
"To evaluate the decrease in intraocular pressure associated with cidofovir (1-[(S)-3-hydroxy-2-(phosphonomethoxy)propyl]cytosine dihydrate; HPMPC) intravitreal injections."3.69Intraocular pressure and aqueous humor dynamics in patients with AIDS treated with intravitreal cidofovir (HPMPC) for cytomegalovirus retinitis. ( Arevalo, JF; Banker, AS; Berry, C; De Clercq, E; Freeman, WR; Ishimoto, B; Munguia, D; Ochabski, R; Rahhal, FM; Taskintuna, I, 1997)
"The initial and maintenance treatment of CMV retinitis must be individualized based on the characteristics of the lesions, including location and extent, specific patient factors, and characteristics of available therapies among others."1.30Guidelines for the treatment of cytomegalovirus diseases in patients with AIDS in the era of potent antiretroviral therapy: recommendations of an international panel. International AIDS Society-USA. ( Benson, CA; Deutsch, TA; Dieterich, DT; Drew, WL; Feinberg, J; Friedberg, DN; Griffiths, PD; Hardy, WD; Holland, GN; Jabs, DA; Jacobson, MA; Kessler, HA; Polis, MA; Powderly, WG; Spector, SA; Walmsley, S; Whitley, RJ, 1998)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.26)18.7374
1990's15 (78.95)18.2507
2000's3 (15.79)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hubacek, P1
Keslova, P1
Formankova, R1
Pochop, P1
Cinek, O1
Zajac, M1
Lochmanova, J1
Stary, J1
Sedlacek, P1
Zambarakji, HJ1
Obi, AA1
Mitchell, SM1
Cheng, L1
Hostetler, KY1
Lee, J1
Koh, HJ1
Beadle, JR1
Bessho, K1
Toyoguchi, M1
Aldern, K1
Bovet, JM1
Freeman, WR7
Besen, G2
Flores-Aguilar, M2
Assil, KK2
Kupperman, BD1
Gangan, P1
Pursley, M2
Munguia, D5
Vuong, C3
De Clercq, E4
Bergeron-Lynn, G3
Huang, JS1
Wiley, CA2
Chandler, B1
Kuppermann, BD1
Connor, JD1
Jabs, DA3
Rahhal, FM3
Arevalo, JF2
Chavez de la Paz, E1
Azen, SP1
Cunningham, ET1
Davis, JL1
Taskintuna, I3
Weinberg, DV1
Feuer, WJ1
Leonard, RE1
Friedberg, DN2
Blick, G1
Garton, T1
Hopkins, U1
LaGravinese, L1
Banker, AS1
Ishimoto, B1
Berry, C1
Ochabski, R1
Capparelli, EV1
Cundy, KC1
Whitley, RJ1
Jacobson, MA1
Holland, GN1
Dieterich, DT1
Hardy, WD1
Polis, MA1
Deutsch, TA1
Feinberg, J1
Spector, SA1
Walmsley, S1
Drew, WL1
Powderly, WG1
Griffiths, PD2
Benson, CA1
Kessler, HA1
Bowen, EF1
Cherrington, JM1
Lamy, PD1
Johnson, MA1
Emery, VC1
Cochereau, I1
Doan, S1
Diraison, MC1
Mousalatti, H1
Guvenisik, N1
Ren, L1
Hoang-Xuan, T1
Robertson, DM1
Riley, FC1
Hermans, PE1

Reviews

1 review available for cytosine and Retinitis

ArticleYear
Cidofovir.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1997, Volume: 115, Issue:6

    Topics: Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Humans; Organophosphonates; Organ

1997

Other Studies

18 other studies available for cytosine and Retinitis

ArticleYear
Cytomegalovirus encephalitis/retinitis in allogeneic haematopoietic stem cell transplant recipient treated successfully with combination of cidofovir and foscarnet.
    Pediatric transplantation, 2009, Volume: 13, Issue:7

    Topics: Adolescent; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Encephalitis, Viral;

2009
Successful treatment of varicella zoster virus retinitis with aggressive intravitreal and systemic antiviral therapy.
    Ocular immunology and inflammation, 2002, Volume: 10, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; Cidofovir; Cytosine; Drug Therapy, Comb

2002
Characterization of a novel intraocular drug-delivery system using crystalline lipid antiviral prodrugs of ganciclovir and cyclic cidofovir.
    Investigative ophthalmology & visual science, 2004, Volume: 45, Issue:11

    Topics: Animals; Antiviral Agents; Area Under Curve; Biological Availability; Chromatography, High Pressure

2004
Long-term therapy for herpes retinitis in an animal model with high-concentrated liposome-encapsulated HPMPC.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1995, Volume: 113, Issue:5

    Topics: Animals; Antiviral Agents; Cidofovir; Cytosine; Disease Models, Animal; Electroretinography; Eye Inf

1995
Long-acting therapy of viral retinitis with (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine.
    The Journal of infectious diseases, 1994, Volume: 169, Issue:3

    Topics: Animals; Antiviral Agents; Cidofovir; Cytosine; Drug Therapy, Combination; Ganciclovir; Herpes Simpl

1994
Liposome-encapsulated (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine for long-acting therapy of viral retinitis.
    The Journal of infectious diseases, 1996, Volume: 173, Issue:1

    Topics: Animals; Antiviral Agents; Cidofovir; Cytosine; Disease Models, Animal; Drug Carriers; Eye Infection

1996
Treatment of cytomegalovirus retinitis in patients with AIDS.
    Annals of internal medicine, 1996, Jul-15, Volume: 125, Issue:2

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cyto

1996
Treatment of cytomegalovirus retinitis with intravitreous cidofovir in patients with AIDS. A preliminary report.
    Annals of internal medicine, 1996, Jul-15, Volume: 125, Issue:2

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Infection

1996
New therapies for cytomegalovirus retinitis in patients with the acquired immunodeficiency syndrome.
    The Western journal of medicine, 1997, Volume: 166, Issue:2

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cyto

1997
Iritis and hypotony after treatment with intravenous cidofovir for cytomegalovirus retinitis.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1997, Volume: 115, Issue:6

    Topics: Adult; Antiviral Agents; Cidofovir; Cohort Studies; Cytomegalovirus Infections; Cytosine; Female; Hu

1997
Hypotony and visual loss with intravenous cidofovir treatment of cytomegalovirus retinitis.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1997, Volume: 115, Issue:6

    Topics: Adult; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Humans; Injections, Intrav

1997
Successful use of cidofovir in treating AIDS-related cytomegalovirus retinitis, encephalitis, and esophagitis.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1997, May-01, Volume: 15, Issue:1

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Infection

1997
Intraocular pressure and aqueous humor dynamics in patients with AIDS treated with intravitreal cidofovir (HPMPC) for cytomegalovirus retinitis.
    American journal of ophthalmology, 1997, Volume: 124, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Adult; Anterior Chamber; Antiviral Agents; Aqueous Humor; Cidofo

1997
Intravitreal and plasma cidofovir concentrations after intravitreal and intravenous administration in AIDS patients with cytomegalovirus retinitis.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 1998, Volume: 14, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; Cidofovir; Cohort Studies; Cytomegalovi

1998
Guidelines for the treatment of cytomegalovirus diseases in patients with AIDS in the era of potent antiretroviral therapy: recommendations of an international panel. International AIDS Society-USA.
    Archives of internal medicine, 1998, May-11, Volume: 158, Issue:9

    Topics: AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antiviral Agents; Cidofovir; Cytomegalovirus

1998
Quantitative changes in cytomegalovirus DNAemia and genetic analysis of the UL97 and UL54 genes in AIDS patients receiving cidofovir following ganciclovir therapy.
    Journal of medical virology, 1999, Volume: 58, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus In

1999
Uveitis in patients treated with intravenous cidofovir.
    Ocular immunology and inflammation, 1999, Volume: 7, Issue:3-4

    Topics: Adult; Anti-HIV Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; HIV Seropositivity; Humans;

1999
Endogenous Candida oculomycosis. Report of two patients treated with flucytosine.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1974, Volume: 91, Issue:1

    Topics: Aged; Antifungal Agents; Autopsy; Candida albicans; Candidiasis; Cytosine; Eye Diseases; Female; Flu

1974