cytosine has been researched along with Renal Insufficiency in 13 studies
Renal Insufficiency: Conditions in which the KIDNEYS perform below the normal level in the ability to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism. Renal insufficiency can be classified by the degree of kidney damage (as measured by the level of PROTEINURIA) and reduction in GLOMERULAR FILTRATION RATE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Leflunomide was selected as a last resort to avoid the nephrotoxicity of cidofovir." | 5.34 | Leflunomide failure to control recurrent cytomegalovirus infection in the setting of renal failure after allogeneic stem cell transplantation. ( Abdelhalim, A; Almyroudis, NG; Battiwalla, M; Becker, J; Elefante, A; McCarthy, A; McCarthy, PL; Paplham, P; Segal, BH; Smith, P, 2007) |
| " Intracellular activation of a small fraction (< 10%) of the dose by cellular kinases leads to prolonged antiviral effects that are not easily predicted from conventional pharmacokinetic studies." | 2.40 | Clinical pharmacokinetics of the antiviral nucleotide analogues cidofovir and adefovir. ( Cundy, KC, 1999) |
| "NC, with renal failure secondary to bilateral dysplastic kidneys, received an LRD renal transplant (tx) at 17 months of age." | 1.40 | Treatment of BK virus-associated nephropathy with CMX001 after kidney transplantation in a young child. ( Habib, S; Latiolais, LS; McClure, GB; Reisman, L; Vanchiere, JA, 2014) |
| "Leflunomide was selected as a last resort to avoid the nephrotoxicity of cidofovir." | 1.34 | Leflunomide failure to control recurrent cytomegalovirus infection in the setting of renal failure after allogeneic stem cell transplantation. ( Abdelhalim, A; Almyroudis, NG; Battiwalla, M; Becker, J; Elefante, A; McCarthy, A; McCarthy, PL; Paplham, P; Segal, BH; Smith, P, 2007) |
| " The dosage of CDV was 1 to 5 mg/kg per week followed by maintenance every other week in some patients." | 1.31 | Cidofovir for cytomegalovirus infection and disease in allogeneic stem cell transplant recipients. The Infectious Diseases Working Party of the European Group for Blood and Marrow Transplantation. ( Bacigalupo, A; Bornhäuser, M; Cesaro, S; Cordonnier, C; Crooks, B; Dekker, A; Deliliers, GL; Einsele, H; Gratecos, N; Klingebiel, T; Ljungman, P; Matthes-Martin, S; Musso, M; Platzbecker, U; Ribaud, P; Tagliaferri, E; Trenschel, R; Ullmann, AJ; Ullmann, J; Wacker, P, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (23.08) | 18.2507 |
| 2000's | 3 (23.08) | 29.6817 |
| 2010's | 5 (38.46) | 24.3611 |
| 2020's | 2 (15.38) | 2.80 |
| Authors | Studies |
|---|---|
| Uzay, A | 1 |
| Gündoğdu, Y | 1 |
| Koşan, B | 1 |
| Yetiş, T | 1 |
| Gür, H | 1 |
| Okuturlar, Y | 1 |
| Kartı, SS | 1 |
| Liang, X | 2 |
| Aranyi, T | 2 |
| Zhou, J | 2 |
| Guan, Y | 2 |
| Hu, H | 2 |
| Liu, H | 2 |
| Susztak, K | 2 |
| Hibbert, KA | 1 |
| Shepard, JO | 1 |
| Lane, RJ | 1 |
| Azar, MM | 1 |
| Reisman, L | 1 |
| Habib, S | 1 |
| McClure, GB | 1 |
| Latiolais, LS | 1 |
| Vanchiere, JA | 1 |
| Egli, A | 1 |
| Helmersen, DS | 1 |
| Taub, K | 1 |
| Hirsch, HH | 1 |
| Johnson, A | 1 |
| Tjon Pian Gi, RE | 2 |
| Dietz, A | 2 |
| Djukic, V | 1 |
| Eckel, HE | 1 |
| Friedrich, G | 2 |
| Golusinski, W | 2 |
| Hantzakos, A | 2 |
| Lawson, G | 2 |
| Remacle, M | 2 |
| Rihkanen, H | 1 |
| Dikkers, FG | 2 |
| Ilmarinen, T | 1 |
| van den Heuvel, ER | 1 |
| Aaltonen, LM | 1 |
| Andersen, J | 1 |
| Brunings, JW | 1 |
| Chirila, M | 1 |
| Ferran Vilà, F | 1 |
| de Gier, HH | 1 |
| Graupp, M | 1 |
| Horcasitas, R | 1 |
| Jackowska, J | 1 |
| Koelmel, JC | 1 |
| Lindner, F | 1 |
| Sittel, C | 1 |
| Weichbold, V | 1 |
| Wierzbicka, M | 1 |
| Battiwalla, M | 1 |
| Paplham, P | 1 |
| Almyroudis, NG | 1 |
| McCarthy, A | 1 |
| Abdelhalim, A | 1 |
| Elefante, A | 1 |
| Smith, P | 1 |
| Becker, J | 1 |
| McCarthy, PL | 1 |
| Segal, BH | 1 |
| Nightingale, SL | 1 |
| Cundy, KC | 1 |
| Ljungman, P | 1 |
| Deliliers, GL | 1 |
| Platzbecker, U | 1 |
| Matthes-Martin, S | 1 |
| Bacigalupo, A | 1 |
| Einsele, H | 1 |
| Ullmann, J | 1 |
| Musso, M | 1 |
| Trenschel, R | 1 |
| Ribaud, P | 1 |
| Bornhäuser, M | 1 |
| Cesaro, S | 1 |
| Crooks, B | 1 |
| Dekker, A | 1 |
| Gratecos, N | 1 |
| Klingebiel, T | 1 |
| Tagliaferri, E | 1 |
| Ullmann, AJ | 1 |
| Wacker, P | 1 |
| Cordonnier, C | 1 |
| Salmaggi, A | 1 |
| Maccagnano, E | 1 |
| Castagna, A | 1 |
| Zeni, S | 1 |
| Fantini, F | 1 |
| Cinque, P | 1 |
| Savoiardo, M | 1 |
1 review available for cytosine and Renal Insufficiency
| Article | Year |
|---|---|
Clinical pharmacokinetics of the antiviral nucleotide analogues cidofovir and adefovir.
Topics: Adenine; Administration, Oral; Animals; Antiviral Agents; Cidofovir; Cytosine; Drug Interactions; Hu | 1999 |
12 other studies available for cytosine and Renal Insufficiency
| Article | Year |
|---|---|
Daily low dose intravesical cidofovir for the treatment of BK virus associated hemorrhagic cystitis after allogeneic stem cell transplantation.
Topics: Antiviral Agents; BK Virus; Cidofovir; Cystitis; Cytosine; Drug-Related Side Effects and Adverse Rea | 2023 |
Tet2- and Tet3- Mediated Cytosine Hydroxymethylation in Six2 Progenitor Cells in Mice Is Critical for Nephron Progenitor Differentiation and Nephron Endowment.
Topics: Animals; Cell Differentiation; Cytosine; Dioxygenases; DNA Methylation; Female; Homeodomain Proteins | 2023 |
Tet2- and Tet3- Mediated Cytosine Hydroxymethylation in Six2 Progenitor Cells in Mice Is Critical for Nephron Progenitor Differentiation and Nephron Endowment.
Topics: Animals; Cell Differentiation; Cytosine; Dioxygenases; DNA Methylation; Female; Homeodomain Proteins | 2023 |
Tet2- and Tet3- Mediated Cytosine Hydroxymethylation in Six2 Progenitor Cells in Mice Is Critical for Nephron Progenitor Differentiation and Nephron Endowment.
Topics: Animals; Cell Differentiation; Cytosine; Dioxygenases; DNA Methylation; Female; Homeodomain Proteins | 2023 |
Tet2- and Tet3- Mediated Cytosine Hydroxymethylation in Six2 Progenitor Cells in Mice Is Critical for Nephron Progenitor Differentiation and Nephron Endowment.
Topics: Animals; Cell Differentiation; Cytosine; Dioxygenases; DNA Methylation; Female; Homeodomain Proteins | 2023 |
Case 1-2018. A 39-Year-Old Woman with Rapidly Progressive Respiratory Failure.
Topics: Adenoviridae; Adenoviridae Infections; Adult; Antiviral Agents; Cidofovir; Cytosine; Diagnosis, Diff | 2018 |
Treatment of BK virus-associated nephropathy with CMX001 after kidney transplantation in a young child.
Topics: Administration, Oral; Biopsy; BK Virus; Child, Preschool; Ciprofloxacin; Creatinine; Cytosine; DNA, | 2014 |
Renal failure five years after lung transplantation due to polyomavirus BK-associated nephropathy.
Topics: Adult; Aged; Cidofovir; Cytosine; Female; Humans; Isoxazoles; Kidney Diseases; Leflunomide; Lung Tra | 2010 |
Treatment of recurrent respiratory papillomatosis and adverse reactions following off-label use of cidofovir (Vistide®).
Topics: Adverse Drug Reaction Reporting Systems; Antiviral Agents; Cidofovir; Cytosine; Injections, Intrales | 2012 |
Safety of intralesional cidofovir in patients with recurrent respiratory papillomatosis: an international retrospective study on 635 RRP patients.
Topics: Antiviral Agents; Cidofovir; Combined Modality Therapy; Cytosine; Female; Head and Neck Neoplasms; H | 2013 |
Leflunomide failure to control recurrent cytomegalovirus infection in the setting of renal failure after allogeneic stem cell transplantation.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Therapy, Co | 2007 |
From the Food and Drug Administration.
Topics: Anti-HIV Agents; Antiviral Agents; Breath Tests; Cidofovir; Cytosine; Helicobacter Infections; Helic | 1996 |
Gilead issues new warnings about cidofovir nephrotoxicity.
Topics: Antiviral Agents; Cidofovir; Cytosine; Drug Monitoring; Humans; Organophosphonates; Organophosphorus | 1997 |
Cidofovir for cytomegalovirus infection and disease in allogeneic stem cell transplant recipients. The Infectious Diseases Working Party of the European Group for Blood and Marrow Transplantation.
Topics: Adolescent; Adult; Antiviral Agents; Child; Child, Preschool; Cidofovir; Cytomegalovirus Infections; | 2001 |
Reversal of CSF positivity for JC virus genome by cidofovir in a patient with systemic lupus erythematosus and progressive multifocal leukoencephalopathy.
Topics: Adult; Antiviral Agents; Brain; Cidofovir; Cytosine; DNA, Viral; Fatal Outcome; Female; Humans; JC V | 2001 |