Page last updated: 2024-10-17

cytosine and Parkinson Disease

cytosine has been researched along with Parkinson Disease in 10 studies

Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)

Research Excerpts

ExcerptRelevanceReference
"Certain mutations (TT homozygous; CT heterozygous; CC wild-type) of the methylenetetrahydrofolate (MTHFR) gene and long-term levodopa application in patients with Parkinson's disease (PD) support onset of hyperhomocysteinemia."7.72MTHFR C677T polymorphism, folic acid and hyperhomocysteinemia in levodopa treated patients with Parkinson's disease. ( Kuhn, W; Müller, T; Woitalla, D, 2004)
"Certain mutations (TT homozygous; CT heterozygous; CC wild-type) of the methylenetetrahydrofolate (MTHFR) gene and long-term levodopa application in patients with Parkinson's disease (PD) support onset of hyperhomocysteinemia."3.72MTHFR C677T polymorphism, folic acid and hyperhomocysteinemia in levodopa treated patients with Parkinson's disease. ( Kuhn, W; Müller, T; Woitalla, D, 2004)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19902 (20.00)18.7374
1990's0 (0.00)18.2507
2000's4 (40.00)29.6817
2010's3 (30.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Hong, J1
Dembo, RS1
DaWalt, LS1
Baker, MW1
Berry-Kravis, E1
Mailick, MR1
Armstrong, MJ1
Jin, Y1
Allen, EG1
Jin, P1
Gopalai, AA1
Lim, SY1
Aziz, ZA1
Lim, SK1
Tan, LP1
Chong, YB1
Tan, CT1
Puvanarajah, S1
Viswanathan, S1
Kuppusamy, R1
Tan, AH1
Lim, TT1
Eow, GB1
Norlinah, MI1
Li, HH1
Zhao, Y1
Ahmad-Annuar, A1
Zheng, T1
Lv, Q1
Lei, X1
Yin, X1
Zhang, B1
GOMIRATO, G1
HYDEN, H1
Woitalla, D1
Kuhn, W1
Müller, T1
Hong, CJ1
Liu, HC1
Liu, TY1
Liao, DL1
Tsai, SJ1
Grünewald, A1
Breedveld, GJ1
Lohmann-Hedrich, K1
Rohé, CF1
König, IR1
Hagenah, J1
Vanacore, N1
Meco, G1
Antonini, A1
Goldwurm, S1
Lesage, S1
Dürr, A1
Binkofski, F1
Siebner, H1
Münchau, A1
Brice, A1
Oostra, BA1
Klein, C1
Bonifati, V1
Pastor, P1
Muñoz, E1
Ezquerra, M1
Obach, V1
Martí, MJ1
Valldeoriola, F1
Tolosa, E1
Oliva, R1
Cheng, CC1
Roth, B1

Reviews

2 reviews available for cytosine and Parkinson Disease

ArticleYear
Diverse and dynamic DNA modifications in brain and diseases.
    Human molecular genetics, 2019, 11-21, Volume: 28, Issue:R2

    Topics: Adenosine; Alzheimer Disease; Animals; Ataxia; Brain; Chromatin; Cytosine; DNA; DNA Methylation; Epi

2019
Some pyrimidines of biological and medicinal interest. 3.
    Progress in medicinal chemistry, 1971, Volume: 8, Issue:1

    Topics: Alkylating Agents; Alloxan; Amino Acids; Animals; Anti-Inflammatory Agents; Anticonvulsants; Antifun

1971

Other Studies

8 other studies available for cytosine and Parkinson Disease

ArticleYear
Mortality in Women across the
    Cells, 2023, 08-24, Volume: 12, Issue:17

    Topics: Adult; Aged, 80 and over; Cognitive Dysfunction; Cytosine; Female; Fragile X Mental Retardation Prot

2023
Lack of association between the LRRK2 A419V variant and Asian Parkinson's disease.
    Annals of the Academy of Medicine, Singapore, 2013, Volume: 42, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alanine; Case-Control Studies; China; Cohort Studies; Cy

2013
Spatial distribution of 5-hydroxymethyl cytosine in rat brain and temporal distribution in striatum.
    Neurochemical research, 2015, Volume: 40, Issue:4

    Topics: 5-Methylcytosine; Animals; Brain; Corpus Striatum; Cytosine; Male; Oxidopamine; Parkinson Disease; R

2015
A BIOCHEMICAL GLIA ERROR IN THE PARKINSON DISEASE.
    Brain : a journal of neurology, 1963, Volume: 86

    Topics: Adenine; Cytosine; Globus Pallidus; Guanine; Neurochemistry; Neuroglia; Neurons; Nucleic Acids; Park

1963
MTHFR C677T polymorphism, folic acid and hyperhomocysteinemia in levodopa treated patients with Parkinson's disease.
    Journal of neural transmission. Supplementum, 2004, Issue:68

    Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Cytosine; Female; Folic Acid; Humans; Hyperhom

2004
Association studies of the adenosine A2a receptor (1976T > C) genetic polymorphism in Parkinson's disease and schizophrenia.
    Journal of neural transmission (Vienna, Austria : 1996), 2005, Volume: 112, Issue:11

    Topics: Age Distribution; Age of Onset; Aged; Asian People; Base Sequence; Brain; Brain Chemistry; Cytosine;

2005
Biological effects of the PINK1 c.1366C>T mutation: implications in Parkinson disease pathogenesis.
    Neurogenetics, 2007, Volume: 8, Issue:2

    Topics: Base Sequence; Cytosine; DNA, Complementary; Family; Female; Genetic Carrier Screening; Homozygote;

2007
Analysis of the coding and the 5' flanking regions of the alpha-synuclein gene in patients with Parkinson's disease.
    Movement disorders : official journal of the Movement Disorder Society, 2001, Volume: 16, Issue:6

    Topics: Aged; Aged, 80 and over; alpha-Synuclein; Base Pair Mismatch; Case-Control Studies; Cytosine; Essent

2001