cytosine has been researched along with Pachymeningitis in 49 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Therapeutic effectiveness of 5-fluorocytosine (5-FC), amphotericin B (Am B) and both in combined administration were retrospectively assessed and compared with one another in 28 patients with cryptococcal meningitis." | 9.04 | Comparison between 5-fluorocytosine, amphotericin B and the combined administration of these agents in the therapeutic effectiveness for cryptococcal meningitis. ( Ikemoto, H; Jimbow, T; Tejima, Y, 1978) |
| "We compared amphotericin B therapy for cryptococcal meningitis with a newer regimen containing both amphotericin B and flucytosine." | 9.04 | A comparison of amphotericin B alone and combined with flucytosine in the treatment of cryptoccal meningitis. ( Alling, DW; Bennett, JE; Bradshaw, M; Cate, TR; Cobbs, CG; Dismukes, WE; Duma, RJ; Fields, BT; Gallis, H; Haywood, H; Leonard, J; McGee, ZA; Medoff, G; Sande, MA; Warner, JF, 1979) |
| "Ketoconazole, amphotericin B, 5-fluorocytosine, and combinations of these drugs were compared as therapy for chronic cryptococcal meningitis in steroid-treated rabbits." | 7.66 | Treatment of experimental cryptococcal meningitis with amphotericin B, 5-fluorocytosine, and ketoconazole. ( Durack, DT; Perfect, JR, 1982) |
| "The authors report a case of colitis, with anatomo-clinical confrontation, during a treatment with flucytosine." | 7.66 | [Iatrogenic colitis during flucytosine treatment for neuromeningeal cryptococcosis]. ( Bentata-Pessayre, M; Callard, P; Delzant, G; Dupont, B; Fond, B; Krivitzky, A, 1983) |
| "The combined use of amphotericin B and 5-fluorocytosine in the treatment of two children with Candida albicans meningitis is described." | 7.65 | Successful treatment of Candida meningitis with amphotericin B and 5-fluorocytosine in combination. ( Chesney, PJ; Marks, MI; Mulvihill, JJ; Salit, IE; Teets, KC, 1976) |
| "In a prospective study from May 1971 to November 1973, 20 consecutive patients with a diagnosis of disseminated cryptococcosis were treated for six weeks with a combination of amphotericin B (20 mg daily) intravenously and flucytosine (150 mg/kg daily) orally." | 7.65 | Therapy of cryptococcosis with a combination of flucytosine and amphotericin B. ( Duma, RJ; Garriques, IL; Mandell, GL; McGehee, RF; Sande, MA; Shadomy, S; Utz, JP; Warner, JF, 1975) |
| "Ketoconazole has been shown to penetrate into brain tissue of mice and cerebrospinal fluid of humans and to improve the course of human coccidioidal meningitis." | 5.27 | Combination of oral flucytosine and ketoconazole as therapy for experimental cryptococcal meningitis. ( Craven, PC; Graybill, JR, 1984) |
| "Further trials of this drug in the treatment of cryptococcosis are recommended." | 5.25 | Two cases of cryptococcal meningitis, one treated with 5-fluorocytosine. ( Campbell, MJ; Gardner-Medwin, D; Ingham, HR; Murray, IG; Watkins, JS, 1969) |
| "Therapeutic effectiveness of 5-fluorocytosine (5-FC), amphotericin B (Am B) and both in combined administration were retrospectively assessed and compared with one another in 28 patients with cryptococcal meningitis." | 5.04 | Comparison between 5-fluorocytosine, amphotericin B and the combined administration of these agents in the therapeutic effectiveness for cryptococcal meningitis. ( Ikemoto, H; Jimbow, T; Tejima, Y, 1978) |
| "We compared amphotericin B therapy for cryptococcal meningitis with a newer regimen containing both amphotericin B and flucytosine." | 5.04 | A comparison of amphotericin B alone and combined with flucytosine in the treatment of cryptoccal meningitis. ( Alling, DW; Bennett, JE; Bradshaw, M; Cate, TR; Cobbs, CG; Dismukes, WE; Duma, RJ; Fields, BT; Gallis, H; Haywood, H; Leonard, J; McGee, ZA; Medoff, G; Sande, MA; Warner, JF, 1979) |
| "Ketoconazole, amphotericin B, 5-fluorocytosine, and combinations of these drugs were compared as therapy for chronic cryptococcal meningitis in steroid-treated rabbits." | 3.66 | Treatment of experimental cryptococcal meningitis with amphotericin B, 5-fluorocytosine, and ketoconazole. ( Durack, DT; Perfect, JR, 1982) |
| "The authors report a case of colitis, with anatomo-clinical confrontation, during a treatment with flucytosine." | 3.66 | [Iatrogenic colitis during flucytosine treatment for neuromeningeal cryptococcosis]. ( Bentata-Pessayre, M; Callard, P; Delzant, G; Dupont, B; Fond, B; Krivitzky, A, 1983) |
| "The combined use of amphotericin B and 5-fluorocytosine in the treatment of two children with Candida albicans meningitis is described." | 3.65 | Successful treatment of Candida meningitis with amphotericin B and 5-fluorocytosine in combination. ( Chesney, PJ; Marks, MI; Mulvihill, JJ; Salit, IE; Teets, KC, 1976) |
| "Treatment with flucytosine of 20 patients with fungal infections gave favorable results in four patients with crytococcal infections, two of four patients with disseminated candidiasis, eight of ten patients with urinary tract infections due to Candida albicans and Torulopsis glabrata, and tow of three patients with miscellaneous infections due to Calbicans." | 3.65 | Treatment of fungal infections with flucytosine. ( Harder, EJ; Hermans, PE, 1975) |
| "In a prospective study from May 1971 to November 1973, 20 consecutive patients with a diagnosis of disseminated cryptococcosis were treated for six weeks with a combination of amphotericin B (20 mg daily) intravenously and flucytosine (150 mg/kg daily) orally." | 3.65 | Therapy of cryptococcosis with a combination of flucytosine and amphotericin B. ( Duma, RJ; Garriques, IL; Mandell, GL; McGehee, RF; Sande, MA; Shadomy, S; Utz, JP; Warner, JF, 1975) |
| "Ketoconazole has been shown to penetrate into brain tissue of mice and cerebrospinal fluid of humans and to improve the course of human coccidioidal meningitis." | 1.27 | Combination of oral flucytosine and ketoconazole as therapy for experimental cryptococcal meningitis. ( Craven, PC; Graybill, JR, 1984) |
| "Further trials of this drug in the treatment of cryptococcosis are recommended." | 1.25 | Two cases of cryptococcal meningitis, one treated with 5-fluorocytosine. ( Campbell, MJ; Gardner-Medwin, D; Ingham, HR; Murray, IG; Watkins, JS, 1969) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 49 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Perfect, JR | 1 |
| Durack, DT | 1 |
| Fond, B | 1 |
| Bentata-Pessayre, M | 1 |
| Krivitzky, A | 1 |
| Callard, P | 1 |
| Dupont, B | 1 |
| Delzant, G | 1 |
| Craven, PC | 1 |
| Graybill, JR | 1 |
| Steckel, RR | 1 |
| Adams, SB | 1 |
| Long, GG | 1 |
| Rebar, AH | 1 |
| Bayardelle, P | 1 |
| Giard, N | 1 |
| Maltais, R | 1 |
| Delorme, J | 1 |
| Brazeau, M | 1 |
| Schønheyder, H | 1 |
| Thestrup-Pedersen, K | 1 |
| Stenderup, A | 1 |
| Esmann, V | 1 |
| Lai, YH | 1 |
| Tsai, JH | 1 |
| Chen, CY | 1 |
| Jimbow, T | 1 |
| Tejima, Y | 1 |
| Ikemoto, H | 1 |
| Bennett, JE | 2 |
| Dismukes, WE | 1 |
| Duma, RJ | 2 |
| Medoff, G | 1 |
| Sande, MA | 2 |
| Gallis, H | 1 |
| Leonard, J | 1 |
| Fields, BT | 1 |
| Bradshaw, M | 1 |
| Haywood, H | 1 |
| McGee, ZA | 1 |
| Cate, TR | 1 |
| Cobbs, CG | 1 |
| Warner, JF | 2 |
| Alling, DW | 1 |
| Graham, DR | 1 |
| Last, JA | 1 |
| Cross, CE | 1 |
| Rao, HK | 1 |
| Myers, GJ | 1 |
| Stewart, JD | 1 |
| Bryan, CS | 1 |
| McFarland, JA | 1 |
| Chesney, PJ | 2 |
| Justman, RA | 1 |
| Bogdanowicz, WM | 1 |
| Diasio, RB | 1 |
| Lakings, DE | 1 |
| Kauffman, CA | 1 |
| Carleton, JA | 1 |
| Frame, PT | 1 |
| Speller, DC | 1 |
| Fakunle, F | 1 |
| Cairns, SA | 1 |
| Stephens, M | 1 |
| Tobias, JS | 1 |
| Wrigley, PF | 1 |
| Shaw, E | 1 |
| Teets, KC | 1 |
| Mulvihill, JJ | 1 |
| Salit, IE | 1 |
| Marks, MI | 2 |
| Hsi, MS | 1 |
| Chen, RC | 1 |
| Hung, TP | 1 |
| Hamilton, JD | 1 |
| Elliott, DM | 1 |
| Ströder, J | 1 |
| Kühner, U | 1 |
| Färber, D | 1 |
| Harder, EJ | 1 |
| Hermans, PE | 1 |
| Fischman, O | 1 |
| de Camargo, ZP | 1 |
| Grinblat, M | 1 |
| Utz, JP | 2 |
| Garriques, IL | 1 |
| Mandell, GL | 1 |
| McGehee, RF | 1 |
| Shadomy, S | 1 |
| Beggs, WH | 1 |
| Kimura, K | 1 |
| Hatakeyama, M | 1 |
| Miyagi, J | 1 |
| Takeda, A | 1 |
| Sumiya, M | 1 |
| Kano, S | 1 |
| Takaku, F | 1 |
| Yamamoto, K | 1 |
| Singhal, BS | 1 |
| Veer, AS | 1 |
| Pastakia, LF | 1 |
| Stanton, KG | 1 |
| Sanderson, CR | 1 |
| Zylstra, W | 1 |
| Hill, HR | 1 |
| Mitchell, TG | 1 |
| Matsen, JM | 1 |
| Quie, PG | 1 |
| Selby, RC | 1 |
| Lopes, NM | 1 |
| Weese, WC | 1 |
| Schope, RW | 1 |
| Tay, CH | 1 |
| Chew, WL | 1 |
| Lim, LC | 1 |
| Spickard, A | 1 |
| Dowell, AR | 1 |
| Stibbins, DE | 1 |
| Jay, AC | 1 |
| List, J | 1 |
| Meyer, R | 1 |
| Axelrod, JL | 1 |
| Halkin, H | 1 |
| Ravid, M | 1 |
| Zulman, J | 1 |
| Reichert, N | 1 |
| Firkin, FC | 1 |
| Holt, RJ | 1 |
| Newman, RL | 1 |
| van den Ende, EW | 1 |
| Hammond, JA | 1 |
| Amoils, RL | 1 |
| Giorgi, DR | 1 |
| dos Reis, JB | 1 |
| Bei, A | 1 |
| dos Reis Filho, JB | 1 |
| Steer, PL | 1 |
| Klite, PD | 1 |
| Eickhoff, TC | 1 |
| McGill, PE | 1 |
| Sequeira, R | 1 |
| Jindani, A | 1 |
| Nguli, ET | 1 |
| Forrester, AT | 1 |
| Fulton, WF | 1 |
| McDonald, R | 1 |
| Greenberg, EN | 1 |
| Kramer, R | 1 |
| Fass, RJ | 1 |
| Perkins, RL | 1 |
| Watkins, JS | 1 |
| Campbell, MJ | 1 |
| Gardner-Medwin, D | 1 |
| Ingham, HR | 1 |
| Murray, IG | 1 |
2 trials available for cytosine and Pachymeningitis
| Article | Year |
|---|---|
Comparison between 5-fluorocytosine, amphotericin B and the combined administration of these agents in the therapeutic effectiveness for cryptococcal meningitis.
Topics: Adult; Aged; Amphotericin B; Clinical Trials as Topic; Cryptococcosis; Cytosine; Drug Administration | 1978 |
A comparison of amphotericin B alone and combined with flucytosine in the treatment of cryptoccal meningitis.
Topics: Adolescent; Adult; Aged; Amphotericin B; Cryptococcosis; Cytosine; Drug Evaluation; Drug Therapy, Co | 1979 |
47 other studies available for cytosine and Pachymeningitis
| Article | Year |
|---|---|
Treatment of experimental cryptococcal meningitis with amphotericin B, 5-fluorocytosine, and ketoconazole.
Topics: Amphotericin B; Animals; Cryptococcosis; Cryptococcus neoformans; Cytosine; Drug Synergism; Drug The | 1982 |
[Iatrogenic colitis during flucytosine treatment for neuromeningeal cryptococcosis].
Topics: Colitis; Cryptococcosis; Cytosine; Flucytosine; Humans; Male; Meningitis; Middle Aged | 1983 |
Combination of oral flucytosine and ketoconazole as therapy for experimental cryptococcal meningitis.
Topics: Amphotericin B; Animals; Cryptococcosis; Cryptococcus neoformans; Cytosine; Drug Synergism; Drug The | 1984 |
Antemortem diagnosis and treatment of cryptococcal meningitis in a horse.
Topics: Amphotericin B; Animals; Cryptococcosis; Cytosine; Drug Therapy, Combination; Flucytosine; Horse Dis | 1982 |
Success with amphotericin B and 5-fluorocytosine in treating cerebral cryptococcoma accompanying cryptococcal meningitis.
Topics: Adult; Amphotericin B; Brain Diseases; Cryptococcosis; Cytosine; Flucytosine; Humans; Male; Meningit | 1982 |
[Cryptococcosis in the light of three cases (author's transl)].
Topics: Adult; Amphotericin B; Cryptococcosis; Cytosine; Female; Flucytosine; Humans; Male; Meningitis; Midd | 1980 |
[Amphotericin B and 5-fluorocytosine treatment in renal transplant recipient with cryptococcal meningitis (author's transl)].
Topics: Adult; Amphotericin B; Cryptococcosis; Cytosine; Flucytosine; Humans; Kidney Transplantation; Male; | 1977 |
Treatment of cryptococcal meningitis.
Topics: Amphotericin B; Cryptococcosis; Cytosine; Drug Therapy, Combination; Flucytosine; Humans; Meningitis | 1979 |
Treatment of cryptococcal meningitis.
Topics: Amphotericin B; Cryptococcosis; Cytosine; Drug Therapy, Combination; Flucytosine; Humans; Meningitis | 1979 |
Candida meningitis in the newborn.
Topics: Administration, Oral; Amphotericin B; Arthritis, Infectious; Candidiasis; Cytosine; Drug Therapy, Co | 1979 |
Cryptococcal meningitis treated with 5-fluorocytosine and amphotericin B.
Topics: Adolescent; Adult; Amphotericin B; Cryptococcosis; Cytosine; Female; Flucytosine; Humans; Male; Meni | 1977 |
Cryptococcal meningitis. Fatal marrow aplasia from combined therapy.
Topics: Adult; Amphotericin B; Bone Marrow Diseases; Cryptococcosis; Cytosine; Drug Synergism; Drug Therapy, | 1978 |
Candida meningitis in newborn infants: a review and report of combined amphotericin B--flucytosine therapy.
Topics: Adolescent; Amphotericin B; Candidiasis; Cytosine; Drug Therapy, Combination; Female; Flucytosine; F | 1978 |
Evidence for conversion of 5-fluorocytosine to 5-fluorouracil in humans: possible factor in 5-fluorocytosine clinical toxicity.
Topics: Capsules; Cryptococcosis; Cytosine; Flucytosine; Fluorouracil; Humans; Kidney; Meningitis | 1978 |
Simple assay for 5-fluorocytosine in the presence of amphotericin B.
Topics: Amphotericin B; Biological Assay; Candida albicans; Candidiasis; Cryptococcosis; Cytosine; Flucytosi | 1976 |
Cryptococcal meningitis complicating systemic lupus erythematosus: two patients treated with flucytosine and amphotericin B.
Topics: Amphotericin B; Cryptococcosis; Cytosine; Drug Resistance, Microbial; Drug Therapy, Combination; Fem | 1977 |
Combination antifungal therapy for cryptococcal meningitis.
Topics: Adult; Aged; Amphotericin B; Cryptococcosis; Cytosine; Drug Therapy, Combination; Flucytosine; Hodgk | 1976 |
Successful treatment of Candida meningitis with amphotericin B and 5-fluorocytosine in combination.
Topics: Amphotericin B; Candidiasis; Child; Child, Preschool; Cytosine; Drug Administration Schedule; Drug T | 1976 |
[Treatment of cryptococcal meningitis with 5-fluorocytosine. Report of 2 cases].
Topics: Adult; Aged; Cryptococcosis; Cytosine; Flucytosine; Humans; Male; Meningitis | 1975 |
Combined activity of amphotericin B and 5-fluorocytosine against Cryptococcus neoformans in vitro and in vivo in mice.
Topics: Amphotericin B; Animals; Cryptococcosis; Cryptococcus; Cryptococcus neoformans; Cytosine; Disease Mo | 1975 |
[Candida albicans meningitis in infancy. Pathogenesis, clinical aspects and chemotherapy].
Topics: Amphotericin B; Antifungal Agents; Benzene Derivatives; Benzyl Compounds; Candida albicans; Candidia | 1975 |
Treatment of fungal infections with flucytosine.
Topics: Adult; Alkaline Phosphatase; Candida; Candida albicans; Candidiasis; Cryptococcosis; Cryptococcus ne | 1975 |
Cryptococcal meningitis. Report on case successfully treated with 5-fluorocytosine.
Topics: Administration, Oral; Adult; Amphotericin B; Cryptococcosis; Cytosine; Flucytosine; Humans; Male; Me | 1975 |
Therapy of cryptococcosis with a combination of flucytosine and amphotericin B.
Topics: Adult; Aged; Amphotericin B; Cryptococcosis; Cytosine; Drug Therapy, Combination; Female; Flucytosin | 1975 |
Mechanisms of synergistic interactions between amphotericin B and flucytosine.
Topics: Amphotericin B; Candida albicans; Cryptococcus neoformans; Cytosine; Drug Resistance, Microbial; Dru | 1986 |
[A case of systemic lupus erythematosus with cryptococcal meningitis successfully treated with amphotericin B and 5-FC].
Topics: Adult; Amphotericin B; Cryptococcosis; Cytosine; Drug Therapy, Combination; Female; Flucytosine; Hum | 1986 |
Cryptococcal meningitis--treated with 5-fluorocytosine and amphotericin B (a case report).
Topics: Amphotericin B; Cryptococcosis; Cytosine; Female; Flucytosine; Humans; Meningitis; Middle Aged | 1974 |
Current and future chemotherapy of central nervous system fungal infections.
Topics: Administration, Oral; Amphotericin B; Arrhythmias, Cardiac; Brain Diseases; Cytosine; Flucytosine; G | 1974 |
The treatment of systemic cryptococcosis with 5-fluorocytosine.
Topics: Adult; Cerebral Ventricles; Cryptococcosis; Cytosine; Female; Flucytosine; Humans; Lung Diseases, Fu | 1974 |
Editorial: Cryptococcosis and 5-fluorocytosine.
Topics: Amphotericin B; Animals; Cryptococcosis; Cytosine; Drug Resistance, Microbial; Drug Therapy, Combina | 1974 |
Recovery from disseminated candidiasis in a premature neonate.
Topics: Amphotericin B; Antifungal Agents; Arthritis, Infectious; Candidiasis; Cytosine; Drug Resistance, Mi | 1974 |
Torulomas (cryptococcal granulomata) of the central nervous system.
Topics: Adult; Amphotericin B; Brain Diseases; Central Nervous System Diseases; Cryptococcosis; Cytosine; Fl | 1973 |
5-Fluorocytosine therapy.
Topics: Adult; Antifungal Agents; Cerebrospinal Fluid; Cryptococcus; Cryptococcus neoformans; Cytosine; Drug | 1972 |
Cryptococcal meningitis: its apparent increased incidence in the Far East.
Topics: Adolescent; Adult; Amphotericin B; Animals; Asian People; Cerebrospinal Fluid Proteins; Child; Colum | 1972 |
Diagnosis and treatment of cryptococcal disease.
Topics: Amphotericin B; Cryptococcosis; Cryptococcus neoformans; Cytosine; Humans; Lung Diseases, Fungal; Me | 1973 |
Therapeutic failure of 5-fluorocytosine in a patient with cryptococcal meningitis and pneumonia.
Topics: Antifungal Agents; Cryptococcosis; Cryptococcus neoformans; Cytosine; Humans; Male; Meningitis; Midd | 1973 |
Fatal aplastic anemia resulting from flucytosine.
Topics: Administration, Oral; Anemia, Aplastic; Antifungal Agents; Cryptococcosis; Cryptococcus neoformans; | 1974 |
Cryptococcal meningitis treated with 5-fluorocytosine and amphotericin B.
Topics: Amphotericin B; Cryptococcosis; Cryptococcus; Cryptococcus neoformans; Cytosine; Drug Resistance, Mi | 1974 |
Therapy of deep-seated fungal infections with 5-fluorocytosine.
Topics: Adult; Aged; Amphotericin B; Anterior Chamber; Aspergillosis; Aspergillus fumigatus; Candida albican | 1974 |
The antimycotic activity of 5-fluorocytosine.
Topics: Adult; Aged; Arthrodermataceae; Aspergillus; Candida; Candidiasis; Child; Child, Preschool; Cryptoco | 1973 |
Cryptococcal meningitis: a case treated with 5-fluorocytosine.
Topics: Aged; Amphotericin B; Antifungal Agents; Cryptococcosis; Cytosine; Female; Flucytosine; Humans; Meni | 1974 |
[Cryptococcosis of the central nervous system. Current experiences of the neurology department of the Escola Paulista de Medicine].
Topics: Administration, Oral; Adolescent; Adult; Amphotericin B; Child; Cryptococcosis; Cytosine; Female; Hu | 1974 |
5-fluorocytosine: an oral antifungal compound. A report on clinical and laboratory experience.
Topics: Administration, Oral; Adult; Aged; Antifungal Agents; Aspergillus; Candida; Candidiasis; Child; Cryp | 1972 |
5-fluorocytosine in the treatment of cryptococcal meningitis.
Topics: Adult; Amphotericin B; Child; Cryptococcosis; Cytosine; Female; Humans; Meningitis | 1969 |
Cryptococcal meningitis.
Topics: Amphotericin B; Child; Child, Preschool; Cryptococcosis; Cytosine; Female; Fluorides; Humans; Male; | 1970 |
5-fluorocytosine in the treatment of cryptococcal and candida mycoses.
Topics: Adult; Aged; Amphotericin B; Antifungal Agents; Blood Urea Nitrogen; Candida; Candidiasis; Cryptococ | 1971 |
Two cases of cryptococcal meningitis, one treated with 5-fluorocytosine.
Topics: Adolescent; Amphotericin B; Cryptococcosis; Cytosine; Female; Fluorides; Humans; Male; Meningitis; M | 1969 |