cytosine has been researched along with Multiple Sclerosis in 7 studies
Multiple Sclerosis: An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Multiple sclerosis is a chronic demyelinating disorder with an unclear etiology." | 5.91 | Association between the Cytosine Hydroxymethylation and the Expression of microRNA in Multiple Sclerosis in Polish Population. ( Basak, J; Kucharska-Lusina, A; Majsterek, I; Piotrzkowska, D, 2023) |
| "In murine severe experimental autoimmune encephalomyelitis (EAE), an animal model for the human disease multiple sclerosis (MS), we tested the efficacy of a 5-halo-6-phenyl pyrimidinone compound, bropirimine (PNU-54461)." | 3.70 | Pharmacology of the biological response modifier bropirimine (PNU-54461) on experimental autoimmune encephalomyelitis (EAE) in mice. ( Brideau, RJ; Buxser, SE; Chapman, DL; Decker, DE; Dunn, CJ; Galinet, LA; Ready, KA; Vroegop, SM, 1999) |
| "Multiple sclerosis is a chronic demyelinating disorder with an unclear etiology." | 1.91 | Association between the Cytosine Hydroxymethylation and the Expression of microRNA in Multiple Sclerosis in Polish Population. ( Basak, J; Kucharska-Lusina, A; Majsterek, I; Piotrzkowska, D, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 4 (57.14) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Basak, J | 1 |
| Piotrzkowska, D | 1 |
| Kucharska-Lusina, A | 1 |
| Majsterek, I | 1 |
| Calabrese, R | 1 |
| Valentini, E | 1 |
| Ciccarone, F | 1 |
| Guastafierro, T | 1 |
| Bacalini, MG | 1 |
| Ricigliano, VA | 1 |
| Zampieri, M | 1 |
| Annibali, V | 1 |
| Mechelli, R | 1 |
| Franceschi, C | 1 |
| Salvetti, M | 1 |
| Caiafa, P | 1 |
| Schmidt, S | 1 |
| Papassotiropoulos, A | 1 |
| Sotgiu, S | 1 |
| Kölsch, H | 1 |
| Arru, G | 1 |
| Fois, ML | 1 |
| Haase, CG | 1 |
| Schmitz, S | 1 |
| König, N | 1 |
| Harzheim, M | 1 |
| Heun, R | 1 |
| Klockgether, T | 1 |
| Gomez-Lira, M | 1 |
| Liguori, M | 1 |
| Magnani, C | 1 |
| Bonamini, D | 1 |
| Salviati, A | 1 |
| Leone, M | 1 |
| Andreoli, V | 1 |
| Trojano, M | 1 |
| Valentino, P | 1 |
| Savettieri, G | 1 |
| Quattrone, A | 1 |
| Pignatti, PF | 1 |
| Momigliano-Richiardi, P | 1 |
| Giordano, M | 1 |
| Cocco, E | 1 |
| Murru, MR | 1 |
| Melis, C | 1 |
| Schirru, L | 1 |
| Solla, E | 1 |
| Lai, M | 1 |
| Rolesu, M | 1 |
| Marrosu, MG | 1 |
| Galimberti, D | 1 |
| Scalabrini, D | 1 |
| Fenoglio, C | 1 |
| Comi, C | 1 |
| De Riz, M | 1 |
| Venturelli, E | 1 |
| Lovati, C | 1 |
| Mariani, C | 1 |
| Monaco, F | 1 |
| Bresolin, N | 1 |
| Scarpini, E | 1 |
| Vroegop, SM | 1 |
| Chapman, DL | 1 |
| Galinet, LA | 1 |
| Decker, DE | 1 |
| Ready, KA | 1 |
| Brideau, RJ | 1 |
| Dunn, CJ | 1 |
| Buxser, SE | 1 |
1 review available for cytosine and Multiple Sclerosis
| Article | Year |
|---|---|
CD45 and multiple sclerosis: the exon 4 C77G polymorphism (additional studies and meta-analysis) and new markers.
Topics: Alleles; Alternative Splicing; Cytosine; Exons; Female; Gene Frequency; Genetic Markers; Genetic Var | 2003 |
6 other studies available for cytosine and Multiple Sclerosis
| Article | Year |
|---|---|
Association between the Cytosine Hydroxymethylation and the Expression of microRNA in Multiple Sclerosis in Polish Population.
Topics: Cytosine; Epigenesis, Genetic; Humans; MicroRNAs; Multiple Sclerosis; Poland | 2023 |
TET2 gene expression and 5-hydroxymethylcytosine level in multiple sclerosis peripheral blood cells.
Topics: 5-Methylcytosine; Adult; Case-Control Studies; Cytosine; Dioxygenases; DNA (Cytosine-5-)-Methyltrans | 2014 |
Investigation of a genetic variation of a variable number tandem repeat polymorphism of interleukin-6 gene in patients with multiple sclerosis.
Topics: Adult; Alleles; Analysis of Variance; Chi-Square Distribution; Cytosine; Female; Genetic Variation; | 2003 |
PTPRC (CD45) C77G mutation does not contribute to multiple sclerosis susceptibility in Sardinian patients.
Topics: Alleles; Chi-Square Distribution; Cytosine; Female; Gene Frequency; Genetic Predisposition to Diseas | 2004 |
CXCL10 haplotypes and multiple sclerosis: association and correlation with clinical course.
Topics: Adolescent; Adult; Aged; Chemokine CXCL10; Chemokines, CXC; Cytosine; Disease Progression; Exons; Fe | 2007 |
Pharmacology of the biological response modifier bropirimine (PNU-54461) on experimental autoimmune encephalomyelitis (EAE) in mice.
Topics: Adjuvants, Immunologic; Animals; Cytosine; Dose-Response Relationship, Drug; Encephalomyelitis, Auto | 1999 |