cytosine has been researched along with Malignant Melanoma in 26 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "The total levels of DNA 5-methylcytosine were determined in a series of related highly metastatic cell lines which had been isolated from the poorly metastatic human melanoma tumor line MeWo." | 7.67 | Reduced levels of DNA 5-methylcytosine in metastatic variants of the human melanoma cell line MeWo. ( Kerbel, RS; Liteplo, RG, 1987) |
| "Because benign nevic cells may also form 'deposits' in lymph nodes (nodal nevus), the pathological evaluation for metastatic melanoma within sentinel lymph nodes can be challenging." | 5.42 | 5-Hydroxymethylcytosine expression in metastatic melanoma versus nodal nevus in sentinel lymph node biopsies. ( Granter, SR; Guo, W; Laga, AC; Lee, JJ; Lian, CG; Murphy, GF; Saavedra, AP; Xu, S; Zhan, Q, 2015) |
| "Mutations in sunlight-induced melanoma arise from cyclobutane pyrimidine dimers (CPDs), DNA photoproducts that are typically created picoseconds after an ultraviolet (UV) photon is absorbed at thymine or cytosine." | 3.81 | Photochemistry. Chemiexcitation of melanin derivatives induces DNA photoproducts long after UV exposure. ( Bacchiocchi, A; Bechara, EJ; Brash, DE; Douki, T; Halaban, R; Mano, CM; Premi, S; Wakamatsu, K; Wallisch, S; Weiner, AB, 2015) |
| "The total levels of DNA 5-methylcytosine were determined in a series of related highly metastatic cell lines which had been isolated from the poorly metastatic human melanoma tumor line MeWo." | 3.67 | Reduced levels of DNA 5-methylcytosine in metastatic variants of the human melanoma cell line MeWo. ( Kerbel, RS; Liteplo, RG, 1987) |
| "Melanoma is an aggressive neoplasm with increasing incidence that is classified by the NCI as a recalcitrant cancer, i." | 1.51 | Thymine DNA glycosylase as a novel target for melanoma. ( Beeharry, N; Bellacosa, A; Bhattacharjee, V; Cosentino, L; Davidson, G; Davidson, I; Devarajan, K; Dorjsuren, DG; Einarson, M; Giordano, A; Jelinek, J; Kadariya, Y; Katz, RA; Larue, L; Mancuso, P; Nicolas, E; Simeonov, A; Sobol, RW; Sun, H; Testa, JR; Tricarico, R; Yen, TJ, 2019) |
| "Because benign nevic cells may also form 'deposits' in lymph nodes (nodal nevus), the pathological evaluation for metastatic melanoma within sentinel lymph nodes can be challenging." | 1.42 | 5-Hydroxymethylcytosine expression in metastatic melanoma versus nodal nevus in sentinel lymph node biopsies. ( Granter, SR; Guo, W; Laga, AC; Lee, JJ; Lian, CG; Murphy, GF; Saavedra, AP; Xu, S; Zhan, Q, 2015) |
| "melanoma is 92." | 1.42 | Diagnostic utility of 5-hydroxymethylcytosine immunohistochemistry in melanocytic proliferations. ( Burns, KH; Rodić, N; Sharma, R; Taube, JM; Zampella, J, 2015) |
| "Mucosal melanomas have genetic alterations distinct from those in cutaneous melanomas." | 1.35 | Esophageal melanomas harbor frequent NRAS mutations unlike melanomas of other mucosal sites. ( Kanai, Y; Kouda, S; Nakanishi, Y; Ogawa, R; Sekine, S, 2009) |
| "Malignant melanoma, an aggressive skin cancer, is accessible to non-invasive IR radiation based surface probes for its identification and grading." | 1.35 | Distinction of malignant melanoma and epidermis using IR micro-spectroscopy and statistical methods. ( Argov, S; Cagnano, E; Hammody, Z; Mordechai, S; Moreh, R; Sahu, RK, 2008) |
| " The best therapeutic response was observed when pyrimidinone was given every 4 days for a total of 7 injections; however, other schedules and dosing frequencies also gave significant responses." | 1.27 | Chemoimmunotherapy of B 16 melanoma and P388 leukemia with cyclophosphamide and pyrimidinones. ( Johnson, MA; Li, LH; Moeller, RB; Wallace, TL, 1984) |
| " Pharmacologic studies demonstrated a significant decrease in the bioavailability of the drug as it was administered in this study." | 1.27 | Phase I study of 2-amino-5-bromo-6-phenyl-4(3H)-pyrimidinone (ABPP), an oral interferon inducer, in cancer patients. ( Fitzpatrick, FA; Gutknecht, GD; Hersh, EM; Reele, SB; Rios, A; Stringfellow, DA, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (30.77) | 18.7374 |
| 1990's | 1 (3.85) | 18.2507 |
| 2000's | 4 (15.38) | 29.6817 |
| 2010's | 11 (42.31) | 24.3611 |
| 2020's | 2 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Carrier, A | 1 |
| Desjobert, C | 1 |
| Ponger, L | 1 |
| Lamant, L | 1 |
| Bustos, M | 1 |
| Torres-Ferreira, J | 1 |
| Henrique, R | 1 |
| Jeronimo, C | 1 |
| Lanfrancone, L | 1 |
| Delmas, A | 1 |
| Favre, G | 1 |
| Daunay, A | 1 |
| Busato, F | 1 |
| Hoon, DSB | 1 |
| Tost, J | 1 |
| Etievant, C | 1 |
| Riond, J | 1 |
| Arimondo, PB | 1 |
| Jin, SG | 1 |
| Pettinga, D | 1 |
| Johnson, J | 1 |
| Li, P | 1 |
| Pfeifer, GP | 1 |
| Mancuso, P | 1 |
| Tricarico, R | 1 |
| Bhattacharjee, V | 1 |
| Cosentino, L | 1 |
| Kadariya, Y | 1 |
| Jelinek, J | 1 |
| Nicolas, E | 1 |
| Einarson, M | 1 |
| Beeharry, N | 1 |
| Devarajan, K | 1 |
| Katz, RA | 1 |
| Dorjsuren, DG | 1 |
| Sun, H | 1 |
| Simeonov, A | 1 |
| Giordano, A | 1 |
| Testa, JR | 1 |
| Davidson, G | 1 |
| Davidson, I | 1 |
| Larue, L | 1 |
| Sobol, RW | 1 |
| Yen, TJ | 1 |
| Bellacosa, A | 1 |
| Sugiyama, T | 1 |
| Chen, Y | 1 |
| Gambichler, T | 1 |
| Sand, M | 1 |
| Skrygan, M | 1 |
| Uchiyama, R | 1 |
| Uhara, H | 1 |
| Uchiyama, A | 1 |
| Ogawa, E | 1 |
| Takazawa, Y | 1 |
| Ashida, A | 1 |
| Koga, H | 1 |
| Hayashi, K | 1 |
| Kiniwa, Y | 1 |
| Okuyama, R | 1 |
| Larson, AR | 1 |
| Dresser, KA | 1 |
| Zhan, Q | 4 |
| Lezcano, C | 2 |
| Woda, BA | 2 |
| Yosufi, B | 1 |
| Thompson, JF | 2 |
| Scolyer, RA | 2 |
| Mihm, MC | 3 |
| Shi, YG | 2 |
| Murphy, GF | 4 |
| Lian, CG | 4 |
| Lee, JJ | 2 |
| Granter, SR | 1 |
| Laga, AC | 1 |
| Saavedra, AP | 1 |
| Guo, W | 1 |
| Xu, S | 2 |
| Premi, S | 1 |
| Wallisch, S | 1 |
| Mano, CM | 1 |
| Weiner, AB | 1 |
| Bacchiocchi, A | 1 |
| Wakamatsu, K | 1 |
| Bechara, EJ | 1 |
| Halaban, R | 1 |
| Douki, T | 1 |
| Brash, DE | 1 |
| Rodić, N | 1 |
| Zampella, J | 1 |
| Sharma, R | 1 |
| Burns, KH | 1 |
| Taube, JM | 1 |
| Cook, M | 1 |
| Wang, TJ | 1 |
| Sekine, S | 1 |
| Nakanishi, Y | 1 |
| Ogawa, R | 1 |
| Kouda, S | 1 |
| Kanai, Y | 1 |
| Franke, JC | 1 |
| Plötz, M | 1 |
| Prokop, A | 1 |
| Geilen, CC | 1 |
| Schmalz, HG | 1 |
| Eberle, J | 1 |
| Xu, Y | 1 |
| Ceol, C | 1 |
| Wu, F | 1 |
| Larson, A | 1 |
| Dresser, K | 1 |
| Xu, W | 1 |
| Tan, L | 1 |
| Hu, Y | 1 |
| Lee, CW | 1 |
| Hu, D | 1 |
| Lian, BQ | 1 |
| Kleffel, S | 1 |
| Yang, Y | 1 |
| Neiswender, J | 1 |
| Khorasani, AJ | 1 |
| Fang, R | 1 |
| Duncan, LM | 1 |
| Kakavand, H | 1 |
| Houvras, Y | 1 |
| Zon, LI | 1 |
| Kaiser, UB | 1 |
| Schatton, T | 1 |
| Calista, D | 1 |
| Raulin, J | 1 |
| Hammody, Z | 1 |
| Argov, S | 1 |
| Sahu, RK | 1 |
| Cagnano, E | 1 |
| Moreh, R | 1 |
| Mordechai, S | 1 |
| Stringfellow, DA | 2 |
| Li, LH | 2 |
| Johnson, MA | 1 |
| Moeller, RB | 1 |
| Wallace, TL | 2 |
| Siu, LL | 1 |
| Attardo, G | 1 |
| Izbicka, E | 1 |
| Lawrence, R | 1 |
| Cerna, C | 1 |
| Gomez, L | 1 |
| Davidson, K | 1 |
| Finkle, C | 1 |
| Marsolais, C | 1 |
| Rowinsky, EK | 1 |
| Von Hoff, DD | 1 |
| Ormerod, EJ | 1 |
| Everett, CA | 1 |
| Finch, M | 1 |
| Hart, IR | 1 |
| Rios, A | 1 |
| Fitzpatrick, FA | 1 |
| Reele, SB | 1 |
| Gutknecht, GD | 1 |
| Hersh, EM | 1 |
| Liteplo, RG | 1 |
| Kerbel, RS | 1 |
| Richard, KA | 1 |
| Tracey, DE | 1 |
| Kappler, JW | 1 |
| Fedorov, NA | 1 |
| Matveenko, VN | 1 |
| Tikhonova, EF | 1 |
1 review available for cytosine and Malignant Melanoma
| Article | Year |
|---|---|
Development in lipid drugs.
Topics: Animals; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Cidofovir; Cowpox virus; Cytosine; | 2005 |
25 other studies available for cytosine and Malignant Melanoma
| Article | Year |
|---|---|
DNA methylome combined with chromosome cluster-oriented analysis provides an early signature for cutaneous melanoma aggressiveness.
Topics: Animals; Chromosomes; CpG Islands; Cytosine; DNA Methylation; Epigenesis, Genetic; Epigenome; Gene E | 2022 |
The major mechanism of melanoma mutations is based on deamination of cytosine in pyrimidine dimers as determined by circle damage sequencing.
Topics: Cytosine; Deamination; DNA Damage; Humans; Melanoma; Mutation; Pyrimidine Dimers; Ultraviolet Rays | 2021 |
Thymine DNA glycosylase as a novel target for melanoma.
Topics: Animals; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cytosine; DNA Methylation; Enzyme Inhibit | 2019 |
Biochemical reconstitution of UV-induced mutational processes.
Topics: 5-Methylcytosine; Cell-Free System; Cytosine; Deamination; DNA Damage; DNA Replication; DNA-Cytosine | 2019 |
Loss of 5-hydroxymethylcytosine and ten-eleven translocation 2 protein expression in malignant melanoma.
Topics: 5-Methylcytosine; Biomarkers, Tumor; Cytosine; Dioxygenases; Disease Progression; DNA-Binding Protei | 2013 |
5-Hydroxymethylcytosine as a useful marker to differentiate between malignant melanomas and benign melanocytic nevi.
Topics: 5-Methylcytosine; Adult; Aged; Aged, 80 and over; Biomarkers; CpG Islands; Cytosine; DNA Methylation | 2014 |
Loss of 5-hydroxymethylcytosine correlates with increasing morphologic dysplasia in melanocytic tumors.
Topics: 5-Methylcytosine; Adult; Aged; Aged, 80 and over; Cytosine; DNA Methylation; Female; Humans; Male; M | 2014 |
5-Hydroxymethylcytosine expression in metastatic melanoma versus nodal nevus in sentinel lymph node biopsies.
Topics: 5-Methylcytosine; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Cytosine; Female; Fluorescent A | 2015 |
Photochemistry. Chemiexcitation of melanin derivatives induces DNA photoproducts long after UV exposure.
Topics: Animals; Cells, Cultured; Cytosine; DNA; DNA Damage; Energy Transfer; Humans; Melanins; Melanocytes; | 2015 |
Diagnostic utility of 5-hydroxymethylcytosine immunohistochemistry in melanocytic proliferations.
Topics: 5-Methylcytosine; Cytosine; Diagnosis, Differential; Humans; Immunohistochemistry; Lymph Nodes; Lymp | 2015 |
Loss of the epigenetic mark, 5-Hydroxymethylcytosine, correlates with small cell/nevoid subpopulations and assists in microstaging of human melanoma.
Topics: 5-Methylcytosine; Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Carcinoma, Small Ce | 2015 |
Esophageal melanomas harbor frequent NRAS mutations unlike melanomas of other mucosal sites.
Topics: Aged; Cytosine; DNA Mutational Analysis; DNA, Neoplasm; Esophageal Neoplasms; Female; Guanine; Human | 2009 |
New caspase-independent but ROS-dependent apoptosis pathways are targeted in melanoma cells by an iron-containing cytosine analogue.
Topics: Apoptosis; Caspases; Cell Line, Tumor; Cytosine; Drug Delivery Systems; Ferrous Compounds; Humans; M | 2010 |
Loss of 5-hydroxymethylcytosine is an epigenetic hallmark of melanoma.
Topics: 5-Methylcytosine; Cytosine; Dioxygenases; DNA-Binding Proteins; Epigenesis, Genetic; Gene Expression | 2012 |
Regression of a cutaneous melanoma metastasis after intralesional cidofovir.
Topics: Antineoplastic Agents; Cidofovir; Cytosine; Humans; Lymphatic Metastasis; Male; Melanoma; Middle Age | 2003 |
Distinction of malignant melanoma and epidermis using IR micro-spectroscopy and statistical methods.
Topics: Biomarkers, Tumor; Cytosine; Discriminant Analysis; DNA, Neoplasm; Epidermis; Guanine; Humans; Melan | 2008 |
Antineoplastic properties of pyrimidinone interferon inducers.
Topics: Animals; Cytosine; Female; Immunity; Interferon Inducers; Interferons; Melanoma; Mice; Mice, Inbred | 1980 |
Chemoimmunotherapy of B 16 melanoma and P388 leukemia with cyclophosphamide and pyrimidinones.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Line; Combined | 1984 |
Activity of (-)-2'-deoxy-3'-oxacytidine (BCH-4556) against human tumor colony-forming units.
Topics: Antineoplastic Agents; Cytosine; Dioxolanes; Female; Humans; Kidney Neoplasms; Melanoma; Ovarian Neo | 1998 |
DNA methylation levels in human and murine melanoma cell lines of varying metastatic potential.
Topics: 5-Methylcytosine; Animals; Azacitidine; Cell Line; Cytosine; DNA, Neoplasm; Humans; Melanoma; Methyl | 1986 |
Phase I study of 2-amino-5-bromo-6-phenyl-4(3H)-pyrimidinone (ABPP), an oral interferon inducer, in cancer patients.
Topics: Adult; Aged; Cytosine; Drug Evaluation; Humans; Interferon Inducers; Interferons; Male; Melanoma; Mi | 1986 |
Reduced levels of DNA 5-methylcytosine in metastatic variants of the human melanoma cell line MeWo.
Topics: 5-Methylcytosine; Animals; Cell Line; Chromatography, High Pressure Liquid; Cytosine; DNA; Humans; H | 1987 |
Mechanism of antitumor action of pyrimidinones in the treatment of B16 melanoma and P388 leukemia.
Topics: Animals; Antibodies; Cell Division; Cyclophosphamide; Cytosine; G(M1) Ganglioside; Glycosphingolipid | 1985 |
The 5-methylcytosine content of DNA: tissue specificity.
Topics: Adrenal Gland Neoplasms; Animals; Carbon Isotopes; Cell Line; Chick Embryo; Clone Cells; Culture Tec | 1971 |
[Utilization of pyrimidine precursors in the tumor and liver of mice with Ehrlich ascites carcinoma].
Topics: Animals; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Cytosine; DNA; DNA, Neoplasm; Liver; Male; Melan | 1970 |