Page last updated: 2024-10-17

cytosine and Lymphoma

cytosine has been researched along with Lymphoma in 18 studies

Lymphoma: A general term for various neoplastic diseases of the lymphoid tissue.

Research Excerpts

ExcerptRelevanceReference
" Importantly, cytosine hypermethylation in the 5'-long terminal repeat (LTR) U3 and R regions was associated with true latency in the lymphoma-derived B-cell line L267 but not with defective latency in YR2 cells."7.76DNA cytosine methylation in the bovine leukemia virus promoter is associated with latency in a lymphoma-derived B-cell line: potential involvement of direct inhibition of cAMP-responsive element (CRE)-binding protein/CRE modulator/activation transcription ( Blazkova, J; Burny, A; Calomme, C; Cardona, C; Colin, L; Dekoninck, A; Guiguen, A; Hirsch, I; Kettmann, R; Merimi, M; Nguyên, TL; Nuttinck, M; Pierard, V; Portetelle, D; Rohr, O; Twizere, JC; Van Driessche, B; Van Lint, C; Vanhulle, C; Vierendeel, V; Wijmeersch, G, 2010)
" Future studies will be needed to address modified dosing according to emerging pharmacokinetic and pharmacodynamic data and combination therapy which may lead to improved clinical benefit for troxacitabine in hematologic malignancies."6.73A phase II multicenter study of troxacitabine in relapsed or refractory lymphoproliferative neoplasms or multiple myeloma. ( Baccarani, M; Belanger, R; Ben-Yehuda, D; Caballero, D; Coiffier, B; Facon, T; Fanin, R; Giles, F; Gregory, SA; Panwalkar, A; Vose, JM, 2007)
" Nucleoside analogs in development for non-Hodgkin's lymphoma (NHL) include clofarabine, troxacitabine, and bendamustine, a hybrid of an alkylating nitrogen mustard group and a purine-like benzimidazole, with demonstrated activity in NHL."4.81Hematologic malignancies: new developments and future treatments. ( Cheson, BD, 2002)
" Importantly, cytosine hypermethylation in the 5'-long terminal repeat (LTR) U3 and R regions was associated with true latency in the lymphoma-derived B-cell line L267 but not with defective latency in YR2 cells."3.76DNA cytosine methylation in the bovine leukemia virus promoter is associated with latency in a lymphoma-derived B-cell line: potential involvement of direct inhibition of cAMP-responsive element (CRE)-binding protein/CRE modulator/activation transcription ( Blazkova, J; Burny, A; Calomme, C; Cardona, C; Colin, L; Dekoninck, A; Guiguen, A; Hirsch, I; Kettmann, R; Merimi, M; Nguyên, TL; Nuttinck, M; Pierard, V; Portetelle, D; Rohr, O; Twizere, JC; Van Driessche, B; Van Lint, C; Vanhulle, C; Vierendeel, V; Wijmeersch, G, 2010)
"We found that several major chromosomal fragile sites in human lymphomas, including the bcl-2 major breakpoint region, bcl-1 major translocation cluster, and c-Myc exon 1-intron 1 boundary, contain distinctive sequences of consecutive cytosines exhibiting a high degree of reactivity with the structure-specific chemical probe bisulfite."3.75Conformational variants of duplex DNA correlated with cytosine-rich chromosomal fragile sites. ( Engelhart, AE; Hatmal, MM; Haworth, IS; Houston, SI; Hud, NV; Lieber, MR; Tsai, AG, 2009)
"The extent of methylation of DNA during the transition of cells from exponential phase of growth to the saturation density has been studied in cultured L5178Y mouse lymphoma cells by the comparison of the degree of 5-methylcytosine formation and the stability of this preformed base in various periods of their growth."3.66DNA methylation in various growth phases of cultured L5178Y murine lymphoblasts. ( Kornacka, L; Malec, J; Sawecka, J, 1979)
" Future studies will be needed to address modified dosing according to emerging pharmacokinetic and pharmacodynamic data and combination therapy which may lead to improved clinical benefit for troxacitabine in hematologic malignancies."2.73A phase II multicenter study of troxacitabine in relapsed or refractory lymphoproliferative neoplasms or multiple myeloma. ( Baccarani, M; Belanger, R; Ben-Yehuda, D; Caballero, D; Coiffier, B; Facon, T; Fanin, R; Giles, F; Gregory, SA; Panwalkar, A; Vose, JM, 2007)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19909 (50.00)18.7374
1990's2 (11.11)18.2507
2000's4 (22.22)29.6817
2010's3 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Frobel, J1
Božić, T1
Lenz, M1
Uciechowski, P1
Han, Y1
Herwartz, R1
Strathmann, K1
Isfort, S1
Panse, J1
Esser, A1
Birkhofer, C1
Gerstenmaier, U1
Kraus, T1
Rink, L1
Koschmieder, S1
Wagner, W1
Tsai, AG1
Engelhart, AE1
Hatmal, MM1
Houston, SI1
Hud, NV1
Haworth, IS1
Lieber, MR1
Pierard, V1
Guiguen, A1
Colin, L1
Wijmeersch, G1
Vanhulle, C1
Van Driessche, B1
Dekoninck, A1
Blazkova, J1
Cardona, C1
Merimi, M1
Vierendeel, V1
Calomme, C1
Nguyên, TL1
Nuttinck, M1
Twizere, JC1
Kettmann, R1
Portetelle, D1
Burny, A1
Hirsch, I1
Rohr, O1
Van Lint, C1
Ruozi, B1
Riva, G1
Belletti, D1
Tosi, G1
Forni, F1
Mucci, A1
Barozzi, P1
Luppi, M2
Vandelli, MA1
Cheson, BD1
MAUTNER, HG1
CHU, SH1
JAFFE, JJ1
SARTORELLI, AC1
EVANS, JS1
MUSSER, EA1
BOSTWICK, L1
MENGEL, GD1
Halfdanarson, TR1
Markovic, SN1
Kalokhe, U1
Vose, JM1
Panwalkar, A1
Belanger, R1
Coiffier, B1
Baccarani, M1
Gregory, SA1
Facon, T1
Fanin, R1
Caballero, D1
Ben-Yehuda, D1
Giles, F1
Burchenal, JH1
Romanov, GA1
Vanyushin, BF1
Mangues, R1
Schwartz, S1
Seidman, I1
Pellicer, A1
Gan, J1
Zhang, YL1
Carter, KB1
Cauthron, RD1
Steinberg, RA1
Sutow, WW1
Sullivan, MP1
Sawecka, J1
Kornacka, L1
Malec, J1
Sneller, MC1
Gunter, KC1
Müller, WE1
Yamazaki, Z1
Zahn, RK1
Fairley, GH1

Reviews

2 reviews available for cytosine and Lymphoma

ArticleYear
Hematologic malignancies: new developments and future treatments.
    Seminars in oncology, 2002, Volume: 29, Issue:4 Suppl 13

    Topics: Adenine Nucleotides; Alemtuzumab; Alkaloids; Antibodies, Monoclonal; Antibodies, Monoclonal, Humaniz

2002
Combination chemotherapy in malignant diseases.
    Journal of the Royal College of Physicians of London, 1971, Volume: 5, Issue:2

    Topics: Adult; Antineoplastic Agents; Asparaginase; Carmustine; Child; Cyclophosphamide; Cytarabine; Cytosin

1971

Trials

1 trial available for cytosine and Lymphoma

ArticleYear
A phase II multicenter study of troxacitabine in relapsed or refractory lymphoproliferative neoplasms or multiple myeloma.
    Leukemia & lymphoma, 2007, Volume: 48, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents; Cytosine; Dioxolanes; Dose-Response Relationship, Drug; Drug Res

2007

Other Studies

15 other studies available for cytosine and Lymphoma

ArticleYear
Leukocyte Counts Based on DNA Methylation at Individual Cytosines.
    Clinical chemistry, 2018, Volume: 64, Issue:3

    Topics: Blood Preservation; Carrier Proteins; CpG Islands; Cytosine; DNA Methylation; Humans; Leukocyte Coun

2018
Conformational variants of duplex DNA correlated with cytosine-rich chromosomal fragile sites.
    The Journal of biological chemistry, 2009, Mar-13, Volume: 284, Issue:11

    Topics: Chromosome Fragility; Chromosomes, Human; Circular Dichroism; Crystallography, X-Ray; Cytosine; DNA;

2009
DNA cytosine methylation in the bovine leukemia virus promoter is associated with latency in a lymphoma-derived B-cell line: potential involvement of direct inhibition of cAMP-responsive element (CRE)-binding protein/CRE modulator/activation transcription
    The Journal of biological chemistry, 2010, Jun-18, Volume: 285, Issue:25

    Topics: Activating Transcription Factor 1; B-Lymphocytes; Chromatin; Cyclic AMP; Cyclic AMP Response Element

2010
Cidofovir-loaded liposomes: an intro-study using BCBL-1 cell line as a model for primary effusion lymphoma.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2010, Oct-09, Volume: 41, Issue:2

    Topics: Antiviral Agents; Cell Line, Tumor; Cidofovir; Cytosine; Flow Cytometry; Humans; Liposomes; Lymphoma

2010
THE SYNTHESIS AND ANTINEOPLASTIC PROPERTIES OF SELENOGUANINE, SELENOCYTOSINE AND RELATED COMPOUNDS.
    Journal of medicinal chemistry, 1963, Volume: 6

    Topics: Animals; Antineoplastic Agents; Chemistry, Pharmaceutical; Cytosine; Guanine; Leukemia L1210; Lympho

1963
THE EFFECT OF 1-BETA-D-ARABINOFURANOSYLCYTOSINE HYDROCHLORIDE ON MURINE NEOPLASMS.
    Cancer research, 1964, Volume: 24

    Topics: Animals; Anti-Bacterial Agents; Antibodies; Antineoplastic Agents; Blood Cells; Carcinoma, Ehrlich T

1964
A non-chemotherapy treatment of a primary effusion lymphoma: durable remission after intracavitary cidofovir in HIV negative PEL refractory to chemotherapy.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2006, Volume: 17, Issue:12

    Topics: Aged; Antineoplastic Agents; Antiviral Agents; Cidofovir; Combined Modality Therapy; Cytosine; HIV S

2006
Geographic chemotherapy--Burkitt's tumor as a stalking horse for leukemia: presidential address.
    Cancer research, 1966, Volume: 26, Issue:12

    Topics: Adult; Africa; Antineoplastic Agents; Child; Cytosine; Female; Follow-Up Studies; Geography; Humans;

1966
Methylation of reiterated sequences in mammalian DNAs. Effects of the tissue type, age, malignancy and hormonal induction.
    Biochimica et biophysica acta, 1981, Apr-27, Volume: 653, Issue:2

    Topics: 5-Methylcytosine; Animals; Carcinoma, Ehrlich Tumor; Cattle; Cattle Diseases; Cytosine; DNA; DNA, Ne

1981
Promoter demethylation in MMTV/N-rasN transgenic mice required for transgene expression and tumorigenesis.
    Molecular carcinogenesis, 1995, Volume: 14, Issue:2

    Topics: 5-Methylcytosine; Age Factors; Animals; Cytosine; Gene Expression; Gene Expression Regulation, Neopl

1995
On the spontaneous mutability of CpG sites in cultured S49 mouse lymphoma cells.
    Somatic cell and molecular genetics, 1999, Volume: 25, Issue:3

    Topics: 5-Methylcytosine; Animals; Arginine; Azacitidine; Cytosine; Dinucleoside Phosphates; DNA Methylation

1999
Childhood cancer: the improving prognosis.
    Postgraduate medicine, 1976, Volume: 59, Issue:2

    Topics: Asparaginase; Child; Cyclophosphamide; Cytosine; Daunorubicin; Doxorubicin; Drug Therapy, Combinatio

1976
DNA methylation in various growth phases of cultured L5178Y murine lymphoblasts.
    Neoplasma, 1979, Volume: 26, Issue:2

    Topics: Animals; Cell Division; Cells, Cultured; Cytosine; DNA, Neoplasm; Leukemia, Experimental; Lymphoma;

1979
DNA methylation alters chromatin structure and regulates Thy-1 expression in EL-4 T cells.
    Journal of immunology (Baltimore, Md. : 1950), 1987, May-15, Volume: 138, Issue:10

    Topics: 5-Methylcytosine; Animals; Antigens, Surface; Azacitidine; Cell Line; Chromatin; Cytosine; Decitabin

1987
[Influence of arabinofuranosylcytosine on DNA synthesis in mouse lymphoma cells and in sea-urchin embryos].
    Hoppe-Seyler's Zeitschrift fur physiologische Chemie, 1972, Volume: 353, Issue:5

    Topics: Animals; Arabinose; Cytosine; Deoxyribonucleases; DNA; DNA, Neoplasm; Embryo, Mammalian; Embryo, Non

1972