cytosine and Liver Cirrhosis, Biliary studies

cytosine and Liver Cirrhosis, Biliary

Liver Cirrhosis, Biliary: FIBROSIS of the hepatic parenchyma due to obstruction of BILE flow (CHOLESTASIS) in the intrahepatic or extrahepatic bile ducts (BILE DUCTS, INTRAHEPATIC; BILE DUCTS, EXTRAHEPATIC). Primary biliary cholangitis involves the destruction of small intra-hepatic bile ducts and decreased bile secretion. Secondary biliary cholangitis is produced by prolonged obstruction of large intrahepatic or extrahepatic bile ducts from a variety of causes.

Research Excerpts

Excerpt	Relevance	Reference
"Autoimmune diseases such as primary biliary cirrhosis (PBC) result from failure in the immune mechanisms that establish and maintain self-tolerance."	1.35	Interacting alleles of the coinhibitory immunoreceptor genes cytotoxic T-lymphocyte antigen 4 and programmed cell-death 1 influence risk and features of primary biliary cirrhosis. ( Atkinson, EJ; Fridley, BL; Juran, BD; Lazaridis, KN; Petersen, GM; Schlicht, EM, 2008)

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (100.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Timeframe

Studies, this research(%)

All Research%

pre-1990

0 (0.00)

18.7374

1990's

0 (0.00)

18.2507

2000's

2 (100.00)

29.6817

2010's

0 (0.00)

24.3611

2020's

0 (0.00)

2.80

Authors

Authors	Studies
Juran, BD	1
Atkinson, EJ	1
Schlicht, EM	1
Fridley, BL	1
Petersen, GM	1
Lazaridis, KN	1
Lecanda, J	1
Urtasun, R	1
Recalde, S	1
Prieto, J	1
Medina, JF	1

Studies

Juran, BD

Atkinson, EJ

Schlicht, EM

Fridley, BL

Petersen, GM

Lazaridis, KN

Lecanda, J

Urtasun, R

Recalde, S

Prieto, J

Medina, JF

Clinical Trials (1)

Trial Overview

Trial	Phase	Enrollment	Study Type	Start Date	Status
Understanding the Genetic Predisposition to the Development of Primary Biliary Cirrhosis (PBC).[NCT01161953]		1,500 participants (Anticipated)	Observational	2002-03-31	Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial

Phase

Enrollment

Study Type

Start Date

Status

Understanding the Genetic Predisposition to the Development of Primary Biliary Cirrhosis (PBC).[NCT01161953]

1,500 participants (Anticipated)

Observational

2002-03-31

Active, not recruiting

[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

2 other studies available for cytosine and Liver Cirrhosis, Biliary

Article	Year
Interacting alleles of the coinhibitory immunoreceptor genes cytotoxic T-lymphocyte antigen 4 and programmed cell-death 1 influence risk and features of primary biliary cirrhosis. Hepatology (Baltimore, Md.), 2008, Volume: 47, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Antigens, CD; Antigens, Differentiation; Apoptosis Regulatory Protei	2008
A novel polymorphism IVS2+843C>T in the alternate promoter b1 of the human AE2 anion exchanger gene. Human mutation, 2001, Volume: 17, Issue:1 Topics: Anion Transport Proteins; Antiporters; Cytosine; Humans; Introns; Liver Cirrhosis, Biliary; Membrane	2001

Article

Year

Interacting alleles of the coinhibitory immunoreceptor genes cytotoxic T-lymphocyte antigen 4 and programmed cell-death 1 influence risk and features of primary biliary cirrhosis.

Hepatology (Baltimore, Md.), 2008, Volume: 47, Issue:2

Topics: Adult; Aged; Aged, 80 and over; Antigens, CD; Antigens, Differentiation; Apoptosis Regulatory Protei

2008

A novel polymorphism IVS2+843C>T in the alternate promoter b1 of the human AE2 anion exchanger gene.

Human mutation, 2001, Volume: 17, Issue:1

Topics: Anion Transport Proteins; Antiporters; Cytosine; Humans; Introns; Liver Cirrhosis, Biliary; Membrane

2001