cytosine has been researched along with Kidney Diseases in 38 studies
Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| "62 mg/kg) both without and with oral probenecid in 9 transplant patients with persistent BK viremia without nephropathy in a crossover design." | 3.79 | Pharmacokinetics of low-dose cidofovir in kidney transplant recipients with BK virus infection. ( Gao, Y; Momper, JD; Randhawa, PS; Schonder, KS; Shapiro, R; Venkataramanan, R; Zhao, Y, 2013) |
| " Three patients suffered adverse events, two related to the hydration regimen associated with cidofovir administration." | 1.35 | Safety and tolerability of cidofovir in high-risk pediatric patients. ( Bhadri, VA; Lee-Horn, L; Shaw, PJ, 2009) |
| " In three patients, accumulation of toxic levels of 5-FC was related to diminished renal function." | 1.26 | Bone marrow toxicity associated with 5-fluorocytosine therapy. ( Frame, PT; Kauffman, CA, 1977) |
| " Renal clearance of 5-FC was about 75% of the creatinine clearance and a corresponding modification of drug dosage should be made in patients with renal insufficiency." | 1.25 | Use of 5-fluorocytosine in patients with impaired renal function. ( Dawborn, JK; Page, MD; Schiavone, DJ, 1973) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (23.68) | 18.7374 |
| 1990's | 2 (5.26) | 18.2507 |
| 2000's | 15 (39.47) | 29.6817 |
| 2010's | 12 (31.58) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Knight, RJ | 1 |
| Gaber, LW | 1 |
| Patel, SJ | 1 |
| DeVos, JM | 1 |
| Moore, LW | 1 |
| Gaber, AO | 1 |
| Mutlu, D | 1 |
| Sağlık, I | 1 |
| Koyun, M | 1 |
| Comak, E | 1 |
| Mutlu, E | 1 |
| Uslu Gökçeoğlu, A | 1 |
| Cağla Doğan, S | 1 |
| Dinçkan, A | 1 |
| Akbaş, SH | 1 |
| Akkaya, B | 1 |
| Akman, S | 1 |
| Süleymanlar, G | 1 |
| Colak, D | 1 |
| Papanicolaou, GA | 1 |
| Lee, YJ | 1 |
| Young, JW | 1 |
| Seshan, SV | 1 |
| Boruchov, AM | 1 |
| Chittick, G | 1 |
| Momméja-Marin, H | 1 |
| Glezerman, IG | 1 |
| Mohamed, M | 1 |
| Parajuli, S | 1 |
| Muth, B | 1 |
| Astor, BC | 1 |
| Panzer, SE | 1 |
| Mandelbrot, D | 1 |
| Zhong, W | 1 |
| Djamali, A | 1 |
| Araya, CE | 1 |
| Lew, JF | 1 |
| Fennell, RS | 1 |
| Neiberger, RE | 1 |
| Dharnidharka, VR | 1 |
| Acott, PD | 1 |
| Cho, JH | 1 |
| Huh, S | 1 |
| Kwon, TG | 1 |
| Choi, JY | 1 |
| Hur, IK | 1 |
| Lee, EY | 1 |
| Park, SH | 1 |
| Kim, YL | 1 |
| Kim, CD | 1 |
| Wu, SW | 1 |
| Chang, HR | 1 |
| Lian, JD | 1 |
| Bhadri, VA | 1 |
| Lee-Horn, L | 1 |
| Shaw, PJ | 1 |
| Pallet, N | 1 |
| Burgard, M | 1 |
| Quamouss, O | 1 |
| Rabant, M | 1 |
| Bererhi, L | 1 |
| Martinez, F | 1 |
| Thervet, E | 1 |
| Anglicheau, D | 1 |
| Noel, LH | 1 |
| Rouzioux, C | 1 |
| Legendre, C | 1 |
| Egli, A | 1 |
| Helmersen, DS | 1 |
| Taub, K | 1 |
| Hirsch, HH | 2 |
| Johnson, A | 1 |
| Sujeet, K | 1 |
| Vasudev, B | 1 |
| Desai, P | 1 |
| Bellizzi, J | 1 |
| Novoa-Takara, L | 1 |
| He, C | 1 |
| El-Meanawy, A | 1 |
| Hakeem, A | 1 |
| Sharma, H | 1 |
| Sharma, A | 1 |
| Dheir, H | 1 |
| Sahin, S | 1 |
| Uyar, M | 1 |
| Gurkan, A | 1 |
| Turunc, V | 1 |
| Kacar, S | 1 |
| Bayirli Turan, D | 1 |
| Basdemir, G | 1 |
| Pereira, T | 1 |
| Rojas, CP | 1 |
| Garcia-Buitrago, MT | 1 |
| Chandar, J | 1 |
| Abitbol, C | 1 |
| Seeherunvong, W | 1 |
| Rusconi, P | 1 |
| Bruce, JH | 1 |
| Zilleruelò, G | 1 |
| Hua, DK | 1 |
| Howard, K | 1 |
| Craig, JC | 1 |
| Chapman, JR | 1 |
| Wong, G | 1 |
| Momper, JD | 1 |
| Zhao, Y | 1 |
| Shapiro, R | 2 |
| Schonder, KS | 1 |
| Gao, Y | 1 |
| Randhawa, PS | 2 |
| Venkataramanan, R | 1 |
| Vats, A | 1 |
| Singh Randhawa, P | 1 |
| Scantlebury, V | 1 |
| Tuzuner, A | 1 |
| Saxena, M | 1 |
| Moritz, ML | 1 |
| Beattie, TJ | 1 |
| Gonwa, T | 1 |
| Green, MD | 1 |
| Ellis, D | 1 |
| Yazaki, M | 1 |
| Liepnieks, JJ | 1 |
| Barats, MS | 1 |
| Cohen, AH | 1 |
| Benson, MD | 1 |
| Kaltenis, P | 1 |
| Steiger, J | 1 |
| Lim, WH | 1 |
| Mathew, TH | 1 |
| Cooper, JE | 1 |
| Bowden, S | 1 |
| Russ, GR | 1 |
| Schwarz, A | 1 |
| Mengel, M | 1 |
| Haller, H | 1 |
| Niedermeyer, J | 1 |
| Wadei, HM | 1 |
| Rule, AD | 1 |
| Lewin, M | 1 |
| Mahale, AS | 1 |
| Khamash, HA | 1 |
| Schwab, TR | 1 |
| Gloor, JM | 1 |
| Textor, SC | 1 |
| Fidler, ME | 1 |
| Lager, DJ | 1 |
| Larson, TS | 1 |
| Stegall, MD | 1 |
| Cosio, FG | 1 |
| Griffin, MD | 1 |
| Josephson, MA | 1 |
| Williams, JW | 1 |
| Chandraker, A | 1 |
| Hu, BC | 1 |
| Chu, SL | 1 |
| Wang, GL | 1 |
| Gao, PJ | 1 |
| Zhu, DL | 1 |
| Wang, JG | 1 |
| Akioka, K | 1 |
| Okamoto, M | 1 |
| Ushigome, H | 1 |
| Nobori, S | 1 |
| Kaihara, S | 1 |
| Yoshimura, N | 1 |
| Demierre, G | 1 |
| Freedman, LR | 1 |
| Kauffman, CA | 1 |
| Frame, PT | 1 |
| Utz, JP | 1 |
| Borel, Y | 1 |
| Lewis, RM | 1 |
| Stollar, BD | 1 |
| Turner, RW | 1 |
| Grigsby, TH | 1 |
| Enright, JR | 1 |
| Chance, HL | 1 |
| Frazier, TC | 1 |
| Womack, CT | 1 |
| Lang, EK | 1 |
| Firkin, FC | 1 |
| Schönebeck, J | 1 |
| Polak, A | 1 |
| Fernex, M | 1 |
| Scholer, HJ | 1 |
| Dawborn, JK | 1 |
| Page, MD | 1 |
| Schiavone, DJ | 1 |
| Ooi, BS | 1 |
| Chen, BT | 1 |
| Lim, CH | 1 |
| Khoo, OT | 1 |
| Chan, DT | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| BK Viremia and BK Virus Nephropathy Post Kidney Transplant Comparison of New Practices With Traditional Approach: A Combined Retrospective Chart Review and Prospective Observational Study[NCT02758288] | 0 participants (Actual) | Observational | 2015-09-30 | Withdrawn | |||
| Studies of the Ocular Complications of AIDS (SOCA)--HPMPC Peripheral CMV Retinitis Trial (HPCRT)[NCT00000142] | Phase 2/Phase 3 | 64 participants (Actual) | Interventional | 1994-04-30 | Completed | ||
| HPMPC (Cidofovir) Peripheral CMV Retinitis Trial Protocol[NCT00000799] | 100 participants | Interventional | Completed | ||||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
(NCT00000142)
Timeframe: All patients enrolled will be followed until a common study closing date
| Intervention | participants (Number) | ||
|---|---|---|---|
| mortality | progression | va loss of 15 letters | |
| Cidofovir (High Dose) | 3 | 5 | 2 |
| Cidofovir (Low Dose) | 7 | 17 | 6 |
| Treatment Deferral | 6 | 20 | 4 |
3 reviews available for cytosine and Kidney Diseases
| Article | Year |
|---|---|
[BK virus-associated nephropathy].
Topics: Adult; Age Factors; Antiviral Agents; BK Virus; Child; Cidofovir; Cytosine; Female; Graft Rejection; | 2003 |
Polyomavirus BK.
Topics: Antiviral Agents; BK Virus; Cidofovir; Cytosine; Humans; Immunocompromised Host; Kidney Diseases; Ki | 2003 |
Polyomavirus-associated nephropathy: update on antiviral strategies.
Topics: Animals; Antiviral Agents; Cidofovir; Cytosine; Humans; Isoxazoles; Kidney Diseases; Kidney Transpla | 2006 |
2 trials available for cytosine and Kidney Diseases
33 other studies available for cytosine and Kidney Diseases
| Article | Year |
|---|---|
Screening for BK viremia reduces but does not eliminate the risk of BK nephropathy: a single-center retrospective analysis.
Topics: Adult; Antiviral Agents; Biopsy; BK Virus; Cidofovir; Cytosine; Early Diagnosis; Female; Glomerular | 2013 |
[BK virus infections in pediatric kidney transplant recipients].
Topics: Adolescent; Antiviral Agents; BK Virus; Child; Cidofovir; Cytosine; DNA, Viral; Female; Graft Reject | 2013 |
Brincidofovir for polyomavirus-associated nephropathy after allogeneic hematopoietic stem cell transplantation.
Topics: BK Virus; Cytomegalovirus Infections; Cytosine; Hematopoietic Stem Cell Transplantation; Humans; Imm | 2015 |
In kidney transplant recipients with BK polyomavirus infection, early BK nephropathy, microvascular inflammation, and serum creatinine are risk factors for graft loss.
Topics: Adult; Antiviral Agents; BK Virus; Cidofovir; Creatinine; Cytosine; Female; Graft Rejection; Humans; | 2016 |
Intermediate dose cidofovir does not cause additive nephrotoxicity in BK virus allograft nephropathy.
Topics: Adolescent; Adult; Antiviral Agents; BK Virus; Child; Child, Preschool; Cidofovir; Cohort Studies; C | 2008 |
Current treatment of polyoma BK nephropathy in pediatric renal transplant patients.
Topics: BK Virus; Child; Cidofovir; Ciprofloxacin; Cytosine; Humans; Immunosuppressive Agents; Kidney Diseas | 2008 |
Association of C-509T and T869C polymorphisms of transforming growth factor-beta1 gene with chronic allograft nephropathy and graft survival in Korean renal transplant recipients.
Topics: Adult; Cytosine; Female; Gene Frequency; Genotype; Histocompatibility Testing; HLA-DR Antigens; Huma | 2008 |
Safety and tolerability of cidofovir in high-risk pediatric patients.
Topics: Adenovirus Infections, Human; Adenoviruses, Human; Adolescent; Adult; Antiviral Agents; Child; Child | 2009 |
Cidofovir may be deleterious in BK virus-associated nephropathy.
Topics: Antiviral Agents; BK Virus; Cidofovir; Cytosine; Graft Survival; Humans; Kidney Diseases; Kidney Tra | 2010 |
Renal failure five years after lung transplantation due to polyomavirus BK-associated nephropathy.
Topics: Adult; Aged; Cidofovir; Cytosine; Female; Humans; Isoxazoles; Kidney Diseases; Leflunomide; Lung Tra | 2010 |
Acute kidney injury requiring dialysis secondary to adenovirus nephritis in renal transplant recipient.
Topics: Adenovirus Infections, Human; Aged; Antiviral Agents; Cidofovir; Cytosine; Female; Humans; Kidney; K | 2011 |
Cidofovir may be deleterious in BK virus-associated nephropathy.
Topics: Antiviral Agents; BK Virus; Cidofovir; Cytosine; Kidney Diseases; Kidney Transplantation; Organophos | 2011 |
Intensive polyoma virus nephropathy treatment as a preferable approach for graft surveillance.
Topics: Adult; Antiviral Agents; Cidofovir; Cytosine; Female; Graft Rejection; Graft Survival; Humans; Immun | 2011 |
A child with BK virus infection: inadequacy of current therapeutic strategies.
Topics: BK Virus; Brain Diseases; Cardiomyopathies; Child; Cidofovir; Cytosine; Encephalomyelitis; Fatal Out | 2012 |
Cost-effectiveness of cidofovir treatment of polyomavirus nephropathy in kidney transplant recipients.
Topics: Antiviral Agents; BK Virus; Cidofovir; Cost-Benefit Analysis; Cytosine; Decision Support Techniques; | 2012 |
Pharmacokinetics of low-dose cidofovir in kidney transplant recipients with BK virus infection.
Topics: Adjuvants, Pharmaceutic; Adult; Aged; Antiviral Agents; Area Under Curve; BK Virus; Cidofovir; Cross | 2013 |
Quantitative viral load monitoring and cidofovir therapy for the management of BK virus-associated nephropathy in children and adults.
Topics: Adult; Antiviral Agents; BK Virus; Child; Child, Preschool; Cidofovir; Cytosine; Female; Humans; Kid | 2003 |
Hereditary systemic amyloidosis associated with a new apolipoprotein AII stop codon mutation Stop78Arg.
Topics: Amino Acid Sequence; Amyloidosis, Familial; Apolipoprotein A-II; Arginine; Base Sequence; Blotting, | 2003 |
Use of cidofovir in polyomavirus BK viral nephropathy in two renal allograft recipients.
Topics: Antiviral Agents; BK Virus; Cidofovir; Cytosine; Female; Humans; Kidney Diseases; Kidney Transplanta | 2003 |
Polyoma virus nephropathy in native kidneys after lung transplantation.
Topics: Adult; Antiviral Agents; Biopsy; BK Virus; Cidofovir; Cisplatin; Cytosine; Graft Rejection; Humans; | 2005 |
Kidney transplant function and histological clearance of virus following diagnosis of polyomavirus-associated nephropathy (PVAN).
Topics: Adult; Antiviral Agents; Biopsy; Cidofovir; Cyclosporine; Cytosine; Female; Follow-Up Studies; Human | 2006 |
Association between genetic variation in transforming growth factors beta1 and beta3 and renal dysfunction in non-diabetic Chinese.
Topics: Adenine; Adult; Aged; Aged, 80 and over; Albuminuria; Asian People; Creatinine; Cytosine; Female; Ge | 2008 |
BK virus-associated nephropathy in a kidney transplant recipient successfully treated with cidofovir, the first case in Japan.
Topics: Antiviral Agents; BK Virus; Cidofovir; Cytosine; Female; Humans; Japan; Kidney Diseases; Kidney Tran | 2008 |
Drugs for non-HIV viral infections.
Topics: 2-Aminopurine; Abnormalities, Drug-Induced; Acyclovir; Amantadine; Antiviral Agents; Cidofovir; Cont | 1997 |
Experimental endocarditis: prophylaxis of Candida albicans infections by 5-fluorocytosine in rabbits.
Topics: Animals; Candida albicans; Candidiasis; Cytosine; Drug Resistance, Microbial; Embolism; Endocarditis | 1979 |
Bone marrow toxicity associated with 5-fluorocytosine therapy.
Topics: Adult; Aged; Bone Marrow Diseases; Cytosine; Female; Flucytosine; Humans; Kidney Diseases; Leukopeni | 1977 |
Current and future chemotherapy of central nervous system fungal infections.
Topics: Administration, Oral; Amphotericin B; Arrhythmias, Cardiac; Brain Diseases; Cytosine; Flucytosine; G | 1974 |
Prevention of murine lupus nephritis by carrier-dependent induction of immunologic tolerance to denatured DNA.
Topics: Adenosine; Age Factors; Animals; Antibodies, Antinuclear; Antibody Formation; Carrier Proteins; Cyto | 1973 |
Anuria secondary to mechanical obstruction caused by a Candida fungus ball.
Topics: Anuria; Candida albicans; Candidiasis; Contrast Media; Cytosine; Female; Fluorine; Herpes Zoster; Hu | 1973 |
Therapy of deep-seated fungal infections with 5-fluorocytosine.
Topics: Adult; Aged; Amphotericin B; Anterior Chamber; Aspergillosis; Aspergillus fumigatus; Candida albican | 1974 |
Pharmacokinetic studies on the oral antimycotic agent 5-fluorocytosine in individuals with normal and impaired kidney function.
Topics: Adult; Aged; Alkaline Phosphatase; Antifungal Agents; Blood Platelets; Body Weight; Creatinine; Cyto | 1973 |
Use of 5-fluorocytosine in patients with impaired renal function.
Topics: Antifungal Agents; Creatinine; Cytosine; Flucytosine; Half-Life; Humans; Kidney; Kidney Diseases | 1973 |
Survival of a patient transplanted with a kidney infected with Cryptococcus neoformans.
Topics: Adult; Amphotericin B; Azathioprine; Creatinine; Cryptococcosis; Cryptococcus; Cytosine; Female; Flu | 1971 |