cytosine has been researched along with Inflammation in 20 studies
Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We have recently shown in in vitro studies that inflammation-mediated halogenated cytosine damage products can mimic 5-methylcytosine in directing enzymatic DNA methylation and in enhancing the binding of methyl-binding proteins whereas certain oxidative damage products inhibit both." | 8.84 | Inflammation-mediated cytosine damage: a mechanistic link between inflammation and the epigenetic alterations in human cancers. ( Sowers, LC; Valinluck, V, 2007) |
| "During chronic inflammation, neutrophil-secreted hypochlorous acid can damage nearby cells inducing the genomic accumulation of 5-chlorocytosine (5ClC), a known inflammation biomarker." | 7.81 | Intrinsic mutagenic properties of 5-chlorocytosine: A mechanistic connection between chronic inflammation and cancer. ( Chang, SC; Delaney, JC; Essigmann, JM; Fedeles, BI; Freudenthal, BD; Li, D; Singh, V; Wilson, SH; Yau, E, 2015) |
| " We have recently shown in in vitro studies that inflammation-mediated halogenated cytosine damage products can mimic 5-methylcytosine in directing enzymatic DNA methylation and in enhancing the binding of methyl-binding proteins whereas certain oxidative damage products inhibit both." | 4.84 | Inflammation-mediated cytosine damage: a mechanistic link between inflammation and the epigenetic alterations in human cancers. ( Sowers, LC; Valinluck, V, 2007) |
| "During chronic inflammation, neutrophil-secreted hypochlorous acid can damage nearby cells inducing the genomic accumulation of 5-chlorocytosine (5ClC), a known inflammation biomarker." | 3.81 | Intrinsic mutagenic properties of 5-chlorocytosine: A mechanistic connection between chronic inflammation and cancer. ( Chang, SC; Delaney, JC; Essigmann, JM; Fedeles, BI; Freudenthal, BD; Li, D; Singh, V; Wilson, SH; Yau, E, 2015) |
| "Mastitis is among the main reasons women cease breastfeeding." | 1.91 | DNA methylation and gene expression changes in mouse mammary tissue during successive lactations: part II - the impact of lactation rank. ( Aubert-Frambourg, A; Castille, J; Chaulot-Talmon, A; De Casanove, C; Germon, P; Hue-Beauvais, C; Ivanova, E; Jammes, H; Laubier, J; Le Provost, F, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.00) | 18.7374 |
| 1990's | 1 (5.00) | 18.2507 |
| 2000's | 5 (25.00) | 29.6817 |
| 2010's | 10 (50.00) | 24.3611 |
| 2020's | 3 (15.00) | 2.80 |
| Authors | Studies |
|---|---|
| Saunders, MJ | 1 |
| Edwards, BS | 1 |
| Zhu, J | 1 |
| Sklar, LA | 1 |
| Graves, SW | 1 |
| Ivanova, E | 1 |
| Hue-Beauvais, C | 1 |
| Chaulot-Talmon, A | 1 |
| Castille, J | 1 |
| Laubier, J | 1 |
| De Casanove, C | 1 |
| Aubert-Frambourg, A | 1 |
| Germon, P | 1 |
| Jammes, H | 1 |
| Le Provost, F | 1 |
| Rump, K | 1 |
| Unterberg, M | 1 |
| Dahlke, A | 1 |
| Nowak, H | 1 |
| Koos, B | 1 |
| Bergmann, L | 1 |
| Siffert, W | 1 |
| Schäfer, ST | 1 |
| Peters, J | 1 |
| Adamzik, M | 1 |
| Rahmel, T | 1 |
| Yan, H | 1 |
| Tan, L | 1 |
| Liu, Y | 1 |
| Huang, N | 1 |
| Cang, J | 1 |
| Wang, H | 1 |
| Seiler, CL | 1 |
| Song, JUM | 1 |
| Kotandeniya, D | 1 |
| Chen, J | 1 |
| Kono, TJY | 1 |
| Han, Q | 1 |
| Colwell, M | 1 |
| Auch, B | 1 |
| Sarver, AL | 1 |
| Upadhyaya, P | 1 |
| Ren, Y | 1 |
| Faulk, C | 1 |
| De Flora, S | 1 |
| La Maestra, S | 1 |
| Chen, Y | 1 |
| Kassie, F | 1 |
| Tretyakova, NY | 1 |
| Pan, Z | 1 |
| Xue, ZY | 1 |
| Li, GF | 1 |
| Sun, ML | 1 |
| Zhang, M | 1 |
| Hao, LY | 1 |
| Tang, QQ | 1 |
| Zhu, LJ | 1 |
| Cao, JL | 1 |
| Madera-Salcedo, IK | 1 |
| Sánchez-Hernández, BE | 1 |
| Svyryd, Y | 1 |
| Esquivel-Velázquez, M | 1 |
| Rodríguez-Rodríguez, N | 1 |
| Trejo-Zambrano, MI | 1 |
| García-González, HB | 1 |
| Hernández-Molina, G | 1 |
| Mutchinick, OM | 1 |
| Alcocer-Varela, J | 1 |
| Rosetti, F | 1 |
| Crispín, JC | 1 |
| De Schutter, T | 1 |
| Andrei, G | 1 |
| Topalis, D | 1 |
| Duraffour, S | 1 |
| Mitera, T | 1 |
| van den Oord, J | 1 |
| Matthys, P | 1 |
| Snoeck, R | 1 |
| Johansson, C | 1 |
| Tumber, A | 1 |
| Che, K | 1 |
| Cain, P | 1 |
| Nowak, R | 1 |
| Gileadi, C | 1 |
| Oppermann, U | 1 |
| Jangiam, W | 1 |
| Tungjai, M | 1 |
| Rithidech, KN | 1 |
| Fedeles, BI | 1 |
| Freudenthal, BD | 1 |
| Yau, E | 1 |
| Singh, V | 1 |
| Chang, SC | 1 |
| Li, D | 1 |
| Delaney, JC | 1 |
| Wilson, SH | 1 |
| Essigmann, JM | 1 |
| Kowalczyk, P | 1 |
| Jaworek, J | 1 |
| Kot, M | 1 |
| Sokolowska, B | 1 |
| Bielen, A | 1 |
| Janowska, B | 1 |
| Ciesla, JM | 1 |
| Szparecki, G | 1 |
| Sados, B | 1 |
| Tudek, B | 1 |
| Lao, VV | 1 |
| Herring, JL | 1 |
| Kim, CH | 1 |
| Darwanto, A | 1 |
| Soto, U | 1 |
| Sowers, LC | 2 |
| Haapakoski, R | 1 |
| Karisola, P | 1 |
| Fyhrquist, N | 1 |
| Savinko, T | 1 |
| Wolff, H | 1 |
| Turjanmaa, K | 1 |
| Palosuo, T | 1 |
| Reunala, T | 1 |
| Lauerma, A | 1 |
| Alenius, H | 1 |
| Jenny, NS | 1 |
| Tracy, RP | 1 |
| Ogg, MS | 1 |
| Luong, le A | 1 |
| Kuller, LH | 1 |
| Arnold, AM | 1 |
| Sharrett, AR | 1 |
| Humphries, SE | 1 |
| GORDON, DM | 1 |
| ADVOCATE, S | 1 |
| Badouard, C | 1 |
| Masuda, M | 1 |
| Nishino, H | 1 |
| Cadet, J | 1 |
| Favier, A | 1 |
| Ravanat, JL | 1 |
| Valinluck, V | 1 |
| Breddemann, A | 1 |
| Läer, S | 1 |
| Schmidt, KG | 1 |
| Harjes, M | 1 |
| Adam, R | 1 |
| Ludwig, A | 1 |
| Niehues, T | 1 |
| Schneider, DT | 1 |
| Karavellas, MP | 1 |
| Plummer, DJ | 1 |
| Macdonald, JC | 1 |
| Torriani, FJ | 1 |
| Shufelt, CL | 1 |
| Azen, SP | 1 |
| Freeman, WR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| [NCT00005692] | 0 participants | Observational | 1992-04-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for cytosine and Inflammation
| Article | Year |
|---|---|
The roles of Jumonji-type oxygenases in human disease.
Topics: Cytosine; DNA Methylation; Epigenesis, Genetic; Humans; Inflammation; Jumonji Domain-Containing Hist | 2014 |
Inflammation-mediated cytosine damage: a mechanistic link between inflammation and the epigenetic alterations in human cancers.
Topics: Animals; Cell Transformation, Neoplastic; Cytosine; DNA Damage; DNA Methylation; Epigenesis, Genetic | 2007 |
18 other studies available for cytosine and Inflammation
| Article | Year |
|---|---|
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr | 2010 |
DNA methylation and gene expression changes in mouse mammary tissue during successive lactations: part II - the impact of lactation rank.
Topics: Animals; Cytosine; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression; Humans; Inflammati | 2023 |
DNA methylation of a NF-κB binding site in the aquaporin 5 promoter impacts on mortality in sepsis.
Topics: Adult; Aged; Aquaporin 5; Cell Line; Computer Simulation; Cytosine; DNA Methylation; Epigenesis, Gen | 2019 |
Ten-eleven translocation methyl-cytosine dioxygenase 2 deficiency exacerbates renal ischemia-reperfusion injury.
Topics: Animals; Cytosine; Dioxygenases; DNA Demethylation; Gene Expression; Hepatitis A Virus Cellular Rece | 2020 |
Inhalation exposure to cigarette smoke and inflammatory agents induces epigenetic changes in the lung.
Topics: Animals; Carcinogens; Cell Proliferation; Chromatography, High Pressure Liquid; CpG Islands; Cytosin | 2020 |
DNA Hydroxymethylation by Ten-eleven Translocation Methylcytosine Dioxygenase 1 and 3 Regulates Nociceptive Sensitization in a Chronic Inflammatory Pain Model.
Topics: 5-Methylcytosine; Animals; Chronic Pain; Cytosine; Dioxygenases; Disease Models, Animal; DNA Methyla | 2017 |
PPP2R2B hypermethylation causes acquired apoptosis deficiency in systemic autoimmune diseases.
Topics: Apoptosis; Autoimmune Diseases; CCCTC-Binding Factor; Cytokines; Cytosine; DNA Methylation; Gene Exp | 2019 |
Reduced tumorigenicity and pathogenicity of cervical carcinoma SiHa cells selected for resistance to cidofovir.
Topics: Animals; Antineoplastic Agents; Antiviral Agents; Apoptosis; Cell Line, Tumor; Cidofovir; Cytosine; | 2013 |
Induction of chronic oxidative stress, chronic inflammation and aberrant patterns of DNA methylation in the liver of titanium-exposed CBA/CaJ mice.
Topics: 5-Methylcytosine; Animals; Chromosomal Instability; Cytosine; DNA Methylation; Dose-Response Relatio | 2015 |
Intrinsic mutagenic properties of 5-chlorocytosine: A mechanistic connection between chronic inflammation and cancer.
Topics: Biomarkers, Tumor; Carcinogenesis; Chromatography, High Pressure Liquid; Cytosine; DNA Mutational An | 2015 |
Inflammation increases oxidative DNA damage repair and stimulates preneoplastic changes in colons of newborn rats.
Topics: Adenine; Animals; Animals, Newborn; Arachidonate 12-Lipoxygenase; Colon; Colonic Neoplasms; Cyclooxy | 2016 |
Incorporation of 5-chlorocytosine into mammalian DNA results in heritable gene silencing and altered cytosine methylation patterns.
Topics: Animals; CHO Cells; Cricetinae; Cricetulus; Cytosine; DNA; DNA Damage; DNA Replication; Gene Silenci | 2009 |
Intradermal cytosine-phosphate-guanosine treatment reduces lung inflammation but induces IFN-γ-mediated airway hyperreactivity in a murine model of natural rubber latex allergy.
Topics: Administration, Cutaneous; Animals; Bronchial Hyperreactivity; CpG Islands; Cytosine; Female; Guanos | 2011 |
In the elderly, interleukin-6 plasma levels and the -174G>C polymorphism are associated with the development of cardiovascular disease.
Topics: Age Factors; Aged; Biomarkers; Cardiovascular Diseases; Case-Control Studies; Cytosine; Female; Foll | 2002 |
VACCINIAL BLEPHAROKERATITIS TREATED WITH CYTOSINE ARABINOSIDE.
Topics: Antiviral Agents; Corneal Ulcer; Cytarabine; Cytosine; Drug Therapy; Eyelids; Humans; Idoxuridine; I | 1965 |
Detection of chlorinated DNA and RNA nucleosides by HPLC coupled to tandem mass spectrometry as potential biomarkers of inflammation.
Topics: Adenine; Biomarkers; Cell Line, Tumor; Chromatography, High Pressure Liquid; Cytosine; Deoxyadenosin | 2005 |
Case report: severe gastrointestinal inflammation and persistent HHV-6B infection in a paediatric cancer patient.
Topics: Anti-Inflammatory Agents; Antineoplastic Agents; Antiviral Agents; Astrocytoma; Cidofovir; Cytosine; | 2007 |
Incidence of immune recovery vitritis in cytomegalovirus retinitis patients following institution of successful highly active antiretroviral therapy.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; California; Cidofovir; Cohort Studies; Cyto | 1999 |