cytosine has been researched along with Glial Cell Tumors in 13 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Gliomas are incurable brain cancers with poor prognosis, with epigenetic dysregulation being a distinctive feature." | 5.72 | Ascorbate content of clinical glioma tissues is related to tumour grade and to global levels of 5-hydroxymethyl cytosine. ( Burgess, ER; Crake, RLI; Dachs, GU; Das, AB; Magon, NJ; Morrin, HR; Phillips, E; Robinson, BA; Royds, JA; Slatter, TL; Vissers, MCM; Wiggins, GAR, 2022) |
| "Gliomas are incurable brain cancers with poor prognosis, with epigenetic dysregulation being a distinctive feature." | 1.72 | Ascorbate content of clinical glioma tissues is related to tumour grade and to global levels of 5-hydroxymethyl cytosine. ( Burgess, ER; Crake, RLI; Dachs, GU; Das, AB; Magon, NJ; Morrin, HR; Phillips, E; Robinson, BA; Royds, JA; Slatter, TL; Vissers, MCM; Wiggins, GAR, 2022) |
| " In vitro studies showed that 5-FC combined with CDase induced significant growth-inhibitory effects on the cultured glioma cells." | 1.27 | Antineoplastic effects in rats of 5-fluorocytosine in combination with cytosine deaminase capsules. ( Ito, T; Katsuragi, T; Kawamoto, K; Kawamura, Y; Matsumura, H; Nishiyama, T; Ohyama, A; Sakai, T; Yamamoto, N, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (15.38) | 18.7374 |
| 1990's | 4 (30.77) | 18.2507 |
| 2000's | 2 (15.38) | 29.6817 |
| 2010's | 4 (30.77) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Crake, RLI | 1 |
| Burgess, ER | 1 |
| Wiggins, GAR | 1 |
| Magon, NJ | 1 |
| Das, AB | 1 |
| Vissers, MCM | 1 |
| Morrin, HR | 1 |
| Royds, JA | 1 |
| Slatter, TL | 1 |
| Robinson, BA | 1 |
| Phillips, E | 1 |
| Dachs, GU | 1 |
| Ahsan, S | 1 |
| Raabe, EH | 1 |
| Haffner, MC | 2 |
| Vaghasia, A | 1 |
| Warren, KE | 1 |
| Quezado, M | 1 |
| Ballester, LY | 1 |
| Nazarian, J | 1 |
| Eberhart, CG | 2 |
| Rodriguez, FJ | 1 |
| Xu, W | 1 |
| Yang, H | 1 |
| Liu, Y | 1 |
| Yang, Y | 1 |
| Wang, P | 2 |
| Kim, SH | 1 |
| Ito, S | 1 |
| Yang, C | 1 |
| Xiao, MT | 1 |
| Liu, LX | 1 |
| Jiang, WQ | 1 |
| Liu, J | 1 |
| Zhang, JY | 1 |
| Wang, B | 1 |
| Frye, S | 1 |
| Zhang, Y | 1 |
| Xu, YH | 1 |
| Lei, QY | 1 |
| Guan, KL | 1 |
| Zhao, SM | 1 |
| Xiong, Y | 1 |
| Müller, T | 1 |
| Gessi, M | 1 |
| Waha, A | 2 |
| Isselstein, LJ | 1 |
| Luxen, D | 1 |
| Freihoff, D | 1 |
| Freihoff, J | 1 |
| Becker, A | 1 |
| Simon, M | 1 |
| Hammes, J | 1 |
| Denkhaus, D | 1 |
| zur Mühlen, A | 1 |
| Pietsch, T | 1 |
| Orr, BA | 1 |
| Nelson, WG | 1 |
| Yegnasubramanian, S | 1 |
| Mobio, TA | 1 |
| Tavan, E | 1 |
| Baudrimont, I | 1 |
| Anane, R | 1 |
| Carratú, MR | 1 |
| Sanni, A | 1 |
| Gbeassor, MF | 1 |
| Shier, TW | 1 |
| Narbonne, JF | 1 |
| Creppy, EE | 1 |
| Kaliberov, SA | 1 |
| Market, JM | 1 |
| Gillespie, GY | 1 |
| Krendelchtchikova, V | 1 |
| Della Manna, D | 1 |
| Sellers, JC | 1 |
| Kaliberova, LN | 1 |
| Black, ME | 1 |
| Buchsbaum, DJ | 1 |
| Nishiyama, T | 2 |
| Kawamura, Y | 2 |
| Kawamoto, K | 2 |
| Matsumura, H | 2 |
| Yamamoto, N | 2 |
| Ito, T | 2 |
| Ohyama, A | 2 |
| Katsuragi, T | 2 |
| Sakai, T | 2 |
| Merlo, A | 1 |
| Herman, JG | 1 |
| Mao, L | 1 |
| Lee, DJ | 1 |
| Gabrielson, E | 1 |
| Burger, PC | 1 |
| Baylin, SB | 1 |
| Sidransky, D | 1 |
| Uyeno, S | 1 |
| Komura, J | 1 |
| Tawa, R | 1 |
| Aoki, Y | 1 |
| Nata, M | 1 |
| Sasano, H | 1 |
| Nakura, H | 1 |
| Sagisaka, K | 1 |
| Sakurai, H | 1 |
| Kayama, T | 1 |
| Yoshimoto, T | 1 |
| Ono, T | 1 |
| Pieper, RO | 2 |
| Patel, S | 1 |
| Ting, SA | 1 |
| Futscher, BW | 1 |
| Costello, JF | 1 |
| Patel, SA | 1 |
| Graunke, DM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Molecular Analysis of Samples From Patients With Diffuse Intrinsic Pontine Glioma and Brainstem Glioma[NCT01106794] | 100 participants (Anticipated) | Observational | 2010-04-30 | Recruiting | |||
| Efficacy and Safety Assessment of Oral LBH589 in Adult Patients With Advanced Soft Tissue Sarcoma After Pre-treatment Failure: an Open-label, Multicenter Phase II Study[NCT01136499] | Phase 2 | 53 participants (Actual) | Interventional | 2010-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
13 other studies available for cytosine and Glial Cell Tumors
| Article | Year |
|---|---|
Ascorbate content of clinical glioma tissues is related to tumour grade and to global levels of 5-hydroxymethyl cytosine.
Topics: Brain Neoplasms; Cytosine; DNA Methylation; Glioma; Humans; Neoplasm Grading; O(6)-Methylguanine-DNA | 2022 |
Increased 5-hydroxymethylcytosine and decreased 5-methylcytosine are indicators of global epigenetic dysregulation in diffuse intrinsic pontine glioma.
Topics: 5-Methylcytosine; Age Factors; Brain Stem Neoplasms; Child; Child, Preschool; Cytosine; DNA Methylat | 2014 |
Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases.
Topics: 5-Methylcytosine; Amino Acid Substitution; Animals; Binding, Competitive; Biocatalysis; Caenorhabdit | 2011 |
Nuclear exclusion of TET1 is associated with loss of 5-hydroxymethylcytosine in IDH1 wild-type gliomas.
Topics: 5-Methylcytosine; Brain Neoplasms; Cell Line, Tumor; Cell Nucleus; Cytosine; Dioxygenases; DNA Methy | 2012 |
Decreased 5-hydroxymethylcytosine is associated with neural progenitor phenotype in normal brain and shorter survival in malignant glioma.
Topics: 5-Methylcytosine; Brain; Cell Differentiation; Cytosine; Glioma; Humans; Immunohistochemistry; Neuro | 2012 |
Comparative study of the toxic effects of fumonisin B1 in rat C6 glioma cells and p53-null mouse embryo fibroblasts.
Topics: 5-Methylcytosine; 8-Hydroxy-2'-Deoxyguanosine; Animals; Apoptosis; Carcinogens, Environmental; Cell | 2003 |
Mutation of Escherichia coli cytosine deaminase significantly enhances molecular chemotherapy of human glioma.
Topics: Adenoviridae; Animals; Antimetabolites; Brain Neoplasms; Cell Line, Tumor; Combined Modality Therapy | 2007 |
[Antineoplastic effect of 5-fluorocytosine and cytosine deaminase on brain tumor (author's transl)].
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cytosine; Cytosine Deaminase; Drug Therapy, Combina | 1982 |
5' CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers.
Topics: 5-Methylcytosine; Alleles; Azacitidine; Base Sequence; Brain Neoplasms; Carcinoma, Non-Small-Cell Lu | 1995 |
Alteration of c-fos gene methylation in human gliomas.
Topics: Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Cytosine; DNA, Neoplasm; Exons; Female; Gen | 1996 |
Methylation of CpG island transcription factor binding sites is unnecessary for aberrant silencing of the human MGMT gene.
Topics: Base Sequence; Binding Sites; CpG Islands; Cytosine; DNA, Neoplasm; Gene Expression; Genetic Linkage | 1996 |
Aberrant silencing of the CpG island-containing human O6-methylguanine DNA methyltransferase gene is associated with the loss of nucleosome-like positioning.
Topics: Base Sequence; Cell Line; Chromatin; Cloning, Molecular; CpG Islands; Cytosine; DNA Methylation; End | 1997 |
Antineoplastic effects in rats of 5-fluorocytosine in combination with cytosine deaminase capsules.
Topics: Animals; Brain Neoplasms; Capsules; Cytosine; Cytosine Deaminase; Drug Evaluation, Preclinical; Drug | 1985 |