Page last updated: 2024-10-17

cytosine and Experimental Hepatoma

cytosine has been researched along with Experimental Hepatoma in 22 studies

Research Excerpts

ExcerptRelevanceReference
"However, the change of 5 hmC level in hepatocellular carcinoma (HCC) and association with clinical outcome were not well defined."5.39Decrease of 5-hydroxymethylcytosine is associated with progression of hepatocellular carcinoma through downregulation of TET1. ( Bian, XW; Bie, P; Chen, X; Cui, Y; Liu, C; Liu, L; Qian, C; Shan, J; Shen, J; Wu, L; Xia, F; Xu, Y; Yang, Z, 2013)
"However, the change of 5 hmC level in hepatocellular carcinoma (HCC) and association with clinical outcome were not well defined."1.39Decrease of 5-hydroxymethylcytosine is associated with progression of hepatocellular carcinoma through downregulation of TET1. ( Bian, XW; Bie, P; Chen, X; Cui, Y; Liu, C; Liu, L; Qian, C; Shan, J; Shen, J; Wu, L; Xia, F; Xu, Y; Yang, Z, 2013)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19909 (40.91)18.7374
1990's7 (31.82)18.2507
2000's5 (22.73)29.6817
2010's1 (4.55)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Liu, C1
Liu, L1
Chen, X1
Shen, J1
Shan, J1
Xu, Y1
Yang, Z1
Wu, L1
Xia, F1
Bie, P1
Cui, Y1
Bian, XW1
Qian, C1
Pogribny, IP4
Shpyleva, SI1
Muskhelishvili, L1
Bagnyukova, TV1
James, SJ4
Beland, FA1
Jernigan, S1
Pogribna, M1
Tantravahi, U1
Guntaka, RV1
Erlanger, BF1
Miller, OJ1
Lu, LJ1
Randerath, E1
Randerath, K1
Sneider, TW1
Goodman, JI3
Counts, JL2
FitzGerald, BE1
Shank, RC1
Miller, BJ1
Tao, L1
Kramer, PM1
Ge, R1
Pereira, MA1
Barbin, A1
Watson, RE1
Parsons, BL1
Culp, SJ1
Manjanatha, MG1
Heflich, RH1
Fujii, S1
Kitano, S1
Ikenaka, K1
Shirasaka, T1
David, S1
de Sennyey, G1
Suzuki, K1
Sugiyama, T1
Ookawara, T1
Kurosawa, T1
Taniguchi, N1
Tratner, I1
Nahon, JL1
Sala-Trepat, JM1
Venetianer, A1
Münzel, P1
Bock, KW1
Daimon, M1
Tsutsumi, K1
Ishikawa, K1
Davie, JR1
Delcuve, GP1
Nickel, BE1
Moirier, R1
Bailey, G1

Other Studies

22 other studies available for cytosine and Experimental Hepatoma

ArticleYear
Decrease of 5-hydroxymethylcytosine is associated with progression of hepatocellular carcinoma through downregulation of TET1.
    PloS one, 2013, Volume: 8, Issue:5

    Topics: 5-Methylcytosine; Animals; Blotting, Western; Carcinoma, Hepatocellular; Cell Line, Tumor; Cytosine;

2013
Role of DNA damage and alterations in cytosine DNA methylation in rat liver carcinogenesis induced by a methyl-deficient diet.
    Mutation research, 2009, Oct-02, Volume: 669, Issue:1-2

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Choline Deficiency; CpG Islands; Cytosine; Deoxyguanosine; Die

2009
De novo methylation of the p16INK4A gene in early preneoplastic liver and tumors induced by folate/methyl deficiency in rats.
    Cancer letters, 2002, Dec-10, Volume: 187, Issue:1-2

    Topics: Adenoma; Animals; Base Sequence; Carcinoma, Hepatocellular; CpG Islands; Cytosine; Diet; DNA Methyla

2002
Genomic hypomethylation is specific for preneoplastic liver in folate/methyl deficient rats and does not occur in non-target tissues.
    Mutation research, 2004, Apr-14, Volume: 548, Issue:1-2

    Topics: Animals; Carcinoma, Hepatocellular; Cytosine; DNA Methylation; DNA Modification Methylases; DNA, Neo

2004
Amplified ribosomal RNA genes in a rat hepatoma cell line are enriched in 5-methylcytosine.
    Proceedings of the National Academy of Sciences of the United States of America, 1981, Volume: 78, Issue:1

    Topics: 5-Methylcytosine; Animals; Cytosine; DNA Restriction Enzymes; DNA, Neoplasm; Electrophoresis, Agar G

1981
DNA hypomethylation in Morris hepatomas.
    Cancer letters, 1983, Volume: 19, Issue:2

    Topics: 5-Methylcytosine; Animals; Cytosine; Deoxyribonuclease HpaII; DNA; DNA Restriction Enzymes; Liver Ne

1983
The 5'-cytosine in CCGG1 is methylated in two eukaryotic DNAs and Msp I is sensitive to methylation at this site.
    Nucleic acids research, 1980, Sep-11, Volume: 8, Issue:17

    Topics: 5-Methylcytosine; Animals; Base Sequence; Cattle; Cytosine; Deoxyribonucleases; DNA; DNA Restriction

1980
Hypomethylation of DNA: a possible nongenotoxic mechanism underlying the role of cell proliferation in carcinogenesis.
    Environmental health perspectives, 1993, Volume: 101 Suppl 5

    Topics: 5-Methylcytosine; Animals; Cell Division; Cytosine; DNA; Female; Liver Neoplasms, Experimental; Male

1993
Comparative analysis of the methylation status of the 5' flanking region of Ha-ras in B6C3F1, C3H/He and C57BL/6 mouse liver.
    Cancer letters, 1993, Dec-10, Volume: 75, Issue:2

    Topics: 5-Methylcytosine; Animals; Base Sequence; Blotting, Southern; Cytosine; DNA Damage; DNA, Neoplasm; F

1993
Methylation status of DNA cytosine during the course of induction of liver cancer in hamsters by hydrazine sulfate.
    Carcinogenesis, 1996, Volume: 17, Issue:12

    Topics: Animals; Carcinogens; Cricetinae; Cytosine; DNA Methylation; Hydrazines; Liver Neoplasms, Experiment

1996
Alterations in hepatic p53 gene methylation patterns during tumor progression with folate/methyl deficiency in the rat.
    Cancer letters, 1997, May-01, Volume: 115, Issue:1

    Topics: Animals; Cytosine; DNA Methylation; DNA Modification Methylases; Folic Acid Deficiency; Genes, p53;

1997
Effect of dichloroacetic acid and trichloroacetic acid on DNA methylation in liver and tumors of female B6C3F1 mice.
    Toxicological sciences : an official journal of the Society of Toxicology, 1998, Volume: 43, Issue:2

    Topics: 5-Methylcytosine; Adenoma; Animals; Carcinogens; Cytosine; Dichloroacetic Acid; DNA Methylation; Fem

1998
Role of etheno DNA adducts in carcinogenesis induced by vinyl chloride in rats.
    IARC scientific publications, 1999, Issue:150

    Topics: Adenine; Animals; Carcinogens; Cytosine; DNA Adducts; Liver Neoplasms, Experimental; Male; Models, B

1999
Effects of phenobarbital on DNA methylation in GC-rich regions of hepatic DNA from mice that exhibit different levels of susceptibility to liver tumorigenesis.
    Toxicological sciences : an official journal of the Society of Toxicology, 2002, Volume: 68, Issue:1

    Topics: Animals; Carcinogens; Cocarcinogenesis; Cytosine; DNA; DNA Methylation; Genetic Predisposition to Di

2002
Occurrence of H-ras codon 61 CAA to AAA mutation during mouse liver tumor progression.
    Carcinogenesis, 2002, Volume: 23, Issue:6

    Topics: Adenine; Animals; Benzo(a)pyrene; Carcinogens; Coal Tar; Codon; Cytosine; Disease Progression; Genes

2002
Effect of coadministration of uracil or cytosine on the anti-tumor activity of clinical doses of 1-(2-tetrahydrofuryl)-5-fluorouracil and level of 5-fluorouracil in rodents.
    Gan, 1979, Volume: 70, Issue:2

    Topics: Administration, Oral; Animals; Cytosine; Drug Synergism; Drug Therapy, Combination; Fluorouracil; Li

1979
[Synthese of 1-(5-deoxy-beta-D-ribo-hexofuranosyl)cytosine and 1-(2,5-dideoxy-beta-D-erythro-hexofuranosyl)cytosine, and their phosphates. Specificity of an mammalian (rat) ribonucleotide-reductase].
    Carbohydrate research, 1979, Volume: 77

    Topics: Animals; Cytosine; Cytosine Nucleotides; Deoxy Sugars; Liver Neoplasms, Experimental; Magnetic Reson

1979
High sensitivity to 5-azacytidine in LEC rats, a strain with a metabolic predisposition to hepatitis and hepatoma: possible involvement of DNA methylation in the expression of cytochrome P-450 and gamma-glutamyl transpeptidase.
    Biochemistry international, 1991, Volume: 23, Issue:1

    Topics: 5-Methylcytosine; Animals; Azacitidine; Cytochrome P-450 Enzyme System; Cytosine; Disease Susceptibi

1991
Albumin and alpha-fetoprotein gene transcription in rat hepatoma cell lines is correlated with specific DNA hypomethylation and altered chromatin structure in the 5' region.
    Molecular and cellular biology, 1987, Volume: 7, Issue:5

    Topics: 5-Methylcytosine; Albumins; alpha-Fetoproteins; Animals; Cell Line; Chromatin; Cytosine; Deoxyribonu

1987
Hypomethylation of c-myc proto-oncogene of N-nitrosomorpholine--induced rat liver nodules and of H4IIE cells.
    Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement, 1989, Volume: 13

    Topics: Animals; Cells, Cultured; Cytosine; DNA; Liver; Liver Neoplasms, Experimental; Male; Methylation; Ni

1989
DNA methylation and the regulation of aldolase B gene expression.
    Journal of biochemistry, 1986, Volume: 100, Issue:5

    Topics: Animals; Brain; Cytosine; DNA; DNA Restriction Enzymes; Fructose-Bisphosphate Aldolase; Gene Express

1986
Reduced levels of histones H1o and H1b, and unaltered content of methylated DNA in rainbow trout hepatocellular carcinoma chromatin.
    Cancer research, 1987, Oct-15, Volume: 47, Issue:20

    Topics: 5-Methylcytosine; Aflatoxin B1; Aflatoxins; Animals; Chromatin; Cytosine; DNA; Histones; Liver; Live

1987