cytosine has been researched along with Disease Exacerbation in 52 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "To compare the regimen of the ganciclovir implant plus oral ganciclovir to one of intravenous cidofovir for the treatment of cytomegalovirus retinitis." | 9.09 | The ganciclovir implant plus oral ganciclovir versus parenteral cidofovir for the treatment of cytomegalovirus retinitis in patients with acquired immunodeficiency syndrome: The Ganciclovir Cidofovir Cytomegalovirus Retinitis Trial. ( , 2001) |
| "To assess whether the size of the cytosine-thymine-guanine (CTG) expansion mutation in myotonic dystrophy predicts progression of conduction system disease and cardiac events." | 7.71 | Does cytosine-thymine-guanine (CTG) expansion size predict cardiac events and electrocardiographic progression in myotonic dystrophy? ( Clarke, NR; Forfar, JC; Hilton-Jones, D; Kelion, AD; Nixon, J, 2001) |
| "However, the change of 5 hmC level in hepatocellular carcinoma (HCC) and association with clinical outcome were not well defined." | 5.39 | Decrease of 5-hydroxymethylcytosine is associated with progression of hepatocellular carcinoma through downregulation of TET1. ( Bian, XW; Bie, P; Chen, X; Cui, Y; Liu, C; Liu, L; Qian, C; Shan, J; Shen, J; Wu, L; Xia, F; Xu, Y; Yang, Z, 2013) |
| "To compare the regimen of the ganciclovir implant plus oral ganciclovir to one of intravenous cidofovir for the treatment of cytomegalovirus retinitis." | 5.09 | The ganciclovir implant plus oral ganciclovir versus parenteral cidofovir for the treatment of cytomegalovirus retinitis in patients with acquired immunodeficiency syndrome: The Ganciclovir Cidofovir Cytomegalovirus Retinitis Trial. ( , 2001) |
| "In spinocerebellar ataxia type 3/Machado-Joseph disease (SCA3/MJD), the expanded cytosine adenine guanine (CAG) repeat in ATXN3 is the causal mutation, and its length is the main factor in determining the age at onset (AO) of clinical symptoms." | 4.02 | CAG Repeat Size Influences the Progression Rate of Spinocerebellar Ataxia Type 3. ( Brunt, ER; de Mattos, EP; de Vries, JJ; Jardim, LB; Kampinga, HH; Leotti, VB; Oliveira, CM; Te Meerman, GJ; Verbeek, DS, 2021) |
| "To assess whether the size of the cytosine-thymine-guanine (CTG) expansion mutation in myotonic dystrophy predicts progression of conduction system disease and cardiac events." | 3.71 | Does cytosine-thymine-guanine (CTG) expansion size predict cardiac events and electrocardiographic progression in myotonic dystrophy? ( Clarke, NR; Forfar, JC; Hilton-Jones, D; Kelion, AD; Nixon, J, 2001) |
| " Dose-dependent asymptomatic proteinuria (39%) and serum creatinine elevation (24%) were the most common adverse events thought to be related to cidofovir." | 2.69 | Randomized, controlled study of the safety and efficacy of intravenous cidofovir for the treatment of relapsing cytomegalovirus retinitis in patients with AIDS. ( Hardy, WD; Holland, GN; Ives, DV; Jaffe, HS; Johnson, M; Kemper, CA; Kramer, F; Kuppermann, BD; Lalezari, JP; Lewis, RA; McKinley, GF; Nelson, R; Northfelt, DW; Ruby, AE; Simon, GL; Stagg, RJ; Weinberg, DV; Wolitz, RA; Youle, M, 1998) |
| "However, the change of 5 hmC level in hepatocellular carcinoma (HCC) and association with clinical outcome were not well defined." | 1.39 | Decrease of 5-hydroxymethylcytosine is associated with progression of hepatocellular carcinoma through downregulation of TET1. ( Bian, XW; Bie, P; Chen, X; Cui, Y; Liu, C; Liu, L; Qian, C; Shan, J; Shen, J; Wu, L; Xia, F; Xu, Y; Yang, Z, 2013) |
| "Nonalcoholic fatty liver disease (NAFLD) is a clinical condition that refers to progressive histological changes ranging from simple steatosis (SS) to nonalcoholic steatohepatitis (NASH)." | 1.39 | Epigenetic modification of liver mitochondrial DNA is associated with histological severity of nonalcoholic fatty liver disease. ( Burgueño, AL; Castaño, GO; Gianotti, TF; Loidl, CF; Mallardi, P; Martino, JS; Pirola, CJ; Rey-Funes, M; Sookoian, S, 2013) |
| "TIMP1 showed association with chronic periodontitis in the Brazilian population (for rs5906435, p = 0." | 1.38 | MMP3 and TIMP1 variants contribute to chronic periodontitis and may be implicated in disease progression. ( de Souza, AP; Garlet, GP; Letra, A; Rylands, RJ; Silva, RM; Silveira, EM; Vieira, AR; Wendell, SK, 2012) |
| "We have used these biomarkers to establish the optimal dosing regimen for treatment and reveal that a single dose of 25 mg/kg of CMX001 can be efficacious at treating lethal mousepox when administered on days 4 or 5 post-infection." | 1.35 | Using biomarkers to stage disease progression in a lethal mousepox model treated with CMX001. ( Buller, RM; Lanier, R; Oberle, C; Painter, G; Parker, S; Robertson, A; Schriewer, J, 2008) |
| "Two families with frontotemporal dementia with parkinsonism linked to chromosome 17 (FTDP-17) resulting from the microtubule associated protein tau (MAPT) gene IVS10+16C>T splice site mutation are reported, members of which showed variable clinical phenotypes at presentation." | 1.35 | Intrafamilial clinical phenotypic heterogeneity with MAPT gene splice site IVS10+16C>T mutation. ( Larner, AJ, 2009) |
| "The discrimination of nonalcoholic steatohepatitis (NASH) from another NAFLD was made by NAFLD activity score (NAS), and a NAS>or=5 was considered NASH." | 1.34 | Methylenetetrahydrofolate reductase C677T mutation and nonalcoholic fatty liver disease. ( Ataç, FB; Bilezikçi, B; Güçlü, M; Kayaselçuk, F; Ozer, B; Serin, E; Verdi, H; Yilmaz, U, 2007) |
| "Idiopathic dilated cardiomyopathy (IDC) has multiple genetic and acquired causes." | 1.34 | The 212A variant of the APJ receptor gene for the endogenous inotrope apelin is associated with slower heart failure progression in idiopathic dilated cardiomyopathy. ( Capestro, A; Dessì-Fulgheri, P; Forleo, C; Guida, P; Iacoviello, M; Pietrucci, F; Pitzalis, M; Rappelli, A; Romito, R; Sarzani, R; Sorrentino, S; Soura, E, 2007) |
| "Relative risks (RRs) of cancer and 95% confidence intervals (CIs) were calculated by Cox proportional hazards regression analysis." | 1.32 | Integrin beta3 Leu33Pro homozygosity and risk of cancer. ( Bojesen, SE; Nordestgaard, BG; Tybjaerg-Hansen, A, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 9 (17.31) | 18.2507 |
| 2000's | 22 (42.31) | 29.6817 |
| 2010's | 20 (38.46) | 24.3611 |
| 2020's | 1 (1.92) | 2.80 |
| Authors | Studies |
|---|---|
| Fetahu, IS | 1 |
| Ma, D | 1 |
| Rabidou, K | 1 |
| Argueta, C | 1 |
| Smith, M | 1 |
| Liu, H | 2 |
| Wu, F | 1 |
| Shi, YG | 1 |
| Leotti, VB | 1 |
| de Vries, JJ | 1 |
| Oliveira, CM | 1 |
| de Mattos, EP | 1 |
| Te Meerman, GJ | 1 |
| Brunt, ER | 1 |
| Kampinga, HH | 1 |
| Jardim, LB | 1 |
| Verbeek, DS | 1 |
| Qiu, C | 2 |
| Hanson, RL | 2 |
| Fufaa, G | 1 |
| Kobes, S | 1 |
| Gluck, C | 2 |
| Huang, J | 2 |
| Chen, Y | 2 |
| Raj, D | 1 |
| Nelson, RG | 1 |
| Knowler, WC | 1 |
| Susztak, K | 2 |
| Chen, G | 1 |
| Chen, H | 1 |
| Ren, S | 1 |
| Xia, M | 1 |
| Zhu, J | 1 |
| Liu, Y | 1 |
| Zhang, L | 1 |
| Tang, L | 1 |
| Sun, L | 1 |
| Dong, Z | 1 |
| Han, SY | 1 |
| Palmer, M | 1 |
| Park, J | 1 |
| Ko, YA | 1 |
| Guan, Y | 1 |
| Sheng, X | 1 |
| Park, ASD | 1 |
| Izquierdo, MC | 1 |
| Mantzaris, I | 1 |
| Verma, A | 1 |
| Pullman, J | 1 |
| Li, H | 1 |
| Gambichler, T | 1 |
| Sand, M | 1 |
| Skrygan, M | 1 |
| Liu, C | 1 |
| Liu, L | 1 |
| Chen, X | 1 |
| Shen, J | 1 |
| Shan, J | 1 |
| Xu, Y | 1 |
| Yang, Z | 1 |
| Wu, L | 1 |
| Xia, F | 1 |
| Bie, P | 1 |
| Cui, Y | 1 |
| Bian, XW | 1 |
| Qian, C | 1 |
| Heidari, Z | 1 |
| Mahmoudzadeh-Sagheb, H | 1 |
| Hashemi, M | 1 |
| Rigi-Ladiz, MA | 1 |
| Thomson, JP | 1 |
| Moggs, JG | 1 |
| Wolf, CR | 1 |
| Meehan, RR | 1 |
| Coppieters, N | 1 |
| Dieriks, BV | 1 |
| Lill, C | 1 |
| Faull, RL | 1 |
| Curtis, MA | 1 |
| Dragunow, M | 1 |
| Wang, Y | 1 |
| Lin, L | 1 |
| Xu, H | 1 |
| Li, T | 1 |
| Zhou, Y | 1 |
| Dan, H | 1 |
| Jiang, L | 1 |
| Liao, G | 1 |
| Zhou, M | 1 |
| Li, L | 1 |
| Zeng, X | 1 |
| Li, J | 1 |
| Chen, Q | 1 |
| Takayama, K | 1 |
| Misawa, A | 1 |
| Suzuki, T | 1 |
| Takagi, K | 1 |
| Hayashizaki, Y | 1 |
| Fujimura, T | 1 |
| Homma, Y | 1 |
| Takahashi, S | 1 |
| Urano, T | 1 |
| Inoue, S | 1 |
| Lawrie, TA | 1 |
| Nordin, A | 1 |
| Chakrabarti, M | 1 |
| Bryant, A | 1 |
| Kaushik, S | 1 |
| Pepas, L | 1 |
| Gok, K | 1 |
| Cemeroglu, O | 1 |
| Cakirbay, H | 1 |
| Gunduz, E | 1 |
| Acar, M | 1 |
| Cetin, EN | 1 |
| Gunduz, M | 1 |
| Demircan, K | 1 |
| Li, S | 1 |
| Garrett-Bakelman, FE | 1 |
| Chung, SS | 1 |
| Sanders, MA | 1 |
| Hricik, T | 1 |
| Rapaport, F | 1 |
| Patel, J | 1 |
| Dillon, R | 1 |
| Vijay, P | 1 |
| Brown, AL | 1 |
| Perl, AE | 1 |
| Cannon, J | 1 |
| Bullinger, L | 1 |
| Luger, S | 1 |
| Becker, M | 1 |
| Lewis, ID | 1 |
| To, LB | 1 |
| Delwel, R | 1 |
| Löwenberg, B | 1 |
| Döhner, H | 1 |
| Döhner, K | 1 |
| Guzman, ML | 1 |
| Hassane, DC | 1 |
| Roboz, GJ | 1 |
| Grimwade, D | 1 |
| Valk, PJ | 1 |
| D'Andrea, RJ | 1 |
| Carroll, M | 1 |
| Park, CY | 1 |
| Neuberg, D | 1 |
| Levine, R | 1 |
| Melnick, AM | 1 |
| Mason, CE | 1 |
| Araya, CE | 1 |
| Lew, JF | 1 |
| Fennell, RS | 1 |
| Neiberger, RE | 1 |
| Dharnidharka, VR | 1 |
| Parker, S | 1 |
| Schriewer, J | 1 |
| Oberle, C | 1 |
| Robertson, A | 1 |
| Lanier, R | 1 |
| Painter, G | 1 |
| Buller, RM | 1 |
| Costa, AM | 1 |
| Guimarães, MC | 1 |
| de Souza, ER | 1 |
| Nóbrega, OT | 1 |
| Bezerra, AC | 1 |
| Larner, AJ | 1 |
| Gupta, HT | 1 |
| Robinson, RA | 2 |
| Murray, RC | 1 |
| Karnell, LH | 1 |
| Smith, RJ | 2 |
| Hoffman, HT | 2 |
| Ozturk, A | 1 |
| Famili, P | 1 |
| Vieira, AR | 2 |
| Letra, A | 1 |
| Silva, RM | 1 |
| Rylands, RJ | 1 |
| Silveira, EM | 1 |
| de Souza, AP | 1 |
| Wendell, SK | 1 |
| Garlet, GP | 1 |
| Pirola, CJ | 1 |
| Gianotti, TF | 1 |
| Burgueño, AL | 1 |
| Rey-Funes, M | 1 |
| Loidl, CF | 1 |
| Mallardi, P | 1 |
| Martino, JS | 1 |
| Castaño, GO | 1 |
| Sookoian, S | 1 |
| Villar-Menéndez, I | 1 |
| Blanch, M | 1 |
| Tyebji, S | 1 |
| Pereira-Veiga, T | 1 |
| Albasanz, JL | 1 |
| Martín, M | 1 |
| Ferrer, I | 1 |
| Pérez-Navarro, E | 1 |
| Barrachina, M | 1 |
| Townsley, CA | 1 |
| Chi, K | 1 |
| Ernst, DS | 1 |
| Belanger, K | 1 |
| Tannock, I | 1 |
| Bjarnason, GA | 1 |
| Stewart, D | 1 |
| Goel, R | 1 |
| Ruether, JD | 1 |
| Siu, LL | 1 |
| Jolivet, J | 2 |
| McIntosh, L | 1 |
| Seymour, L | 1 |
| Moore, MJ | 1 |
| Bojesen, SE | 1 |
| Tybjaerg-Hansen, A | 1 |
| Nordestgaard, BG | 1 |
| Abdulkadyrov, KM | 1 |
| Gritsaev, SV | 1 |
| Bessmel'tsev, SS | 1 |
| Martynkevich, IS | 1 |
| Tiranova, SA | 1 |
| Blinov, MN | 1 |
| Osipova, RI | 1 |
| Thibaudin, L | 1 |
| Berthoux, P | 1 |
| Thibaudin, D | 1 |
| Mariat, C | 1 |
| Berthoux, F | 1 |
| Powell, IJ | 1 |
| Land, SJ | 1 |
| Dey, J | 1 |
| Heilbrun, LK | 1 |
| Hughes, MR | 1 |
| Sakr, W | 1 |
| Everson, RB | 1 |
| Lapointe, R | 1 |
| Létourneau, R | 1 |
| Steward, W | 1 |
| Hawkins, RE | 1 |
| Batist, G | 1 |
| Vincent, M | 1 |
| Whittom, R | 1 |
| Eatock, M | 1 |
| Moore, M | 1 |
| Vandecasteele, SJ | 1 |
| Maes, B | 1 |
| Claes, K | 1 |
| Sciot, R | 1 |
| Vanrenterghem, Y | 1 |
| Khalil, MS | 1 |
| El Nahas, AM | 1 |
| Blakemore, AI | 1 |
| Inglis, AF | 1 |
| Wemer, RD | 1 |
| Lee, JH | 1 |
| Galimberti, D | 1 |
| Scalabrini, D | 1 |
| Fenoglio, C | 1 |
| Comi, C | 1 |
| De Riz, M | 1 |
| Venturelli, E | 1 |
| Lovati, C | 1 |
| Mariani, C | 1 |
| Monaco, F | 1 |
| Bresolin, N | 1 |
| Scarpini, E | 1 |
| Serin, E | 1 |
| Güçlü, M | 1 |
| Ataç, FB | 1 |
| Verdi, H | 1 |
| Kayaselçuk, F | 1 |
| Ozer, B | 1 |
| Bilezikçi, B | 1 |
| Yilmaz, U | 1 |
| Sarzani, R | 1 |
| Forleo, C | 1 |
| Pietrucci, F | 1 |
| Capestro, A | 1 |
| Soura, E | 1 |
| Guida, P | 1 |
| Sorrentino, S | 1 |
| Iacoviello, M | 1 |
| Romito, R | 1 |
| Dessì-Fulgheri, P | 1 |
| Pitzalis, M | 1 |
| Rappelli, A | 1 |
| Rahhal, FM | 3 |
| Arevalo, JF | 3 |
| Chavez de la Paz, E | 2 |
| Munguia, D | 3 |
| Azen, SP | 2 |
| Freeman, WR | 3 |
| Taskintuna, I | 2 |
| Lalezari, JP | 2 |
| Stagg, RJ | 2 |
| Kuppermann, BD | 2 |
| Holland, GN | 2 |
| Kramer, F | 2 |
| Ives, DV | 2 |
| Youle, M | 2 |
| Robinson, MR | 1 |
| Drew, WL | 1 |
| Jaffe, HS | 2 |
| Banker, AS | 1 |
| De Clercq, E | 1 |
| Brinkman, BM | 1 |
| Huizinga, TW | 1 |
| Kurban, SS | 1 |
| van der Velde, EA | 1 |
| Schreuder, GM | 1 |
| Hazes, JM | 1 |
| Breedveld, FC | 1 |
| Verweij, CL | 1 |
| McKinley, GF | 1 |
| Kemper, CA | 1 |
| Nelson, R | 1 |
| Hardy, WD | 1 |
| Northfelt, DW | 1 |
| Johnson, M | 1 |
| Lewis, RA | 1 |
| Weinberg, DV | 1 |
| Simon, GL | 1 |
| Wolitz, RA | 1 |
| Ruby, AE | 1 |
| Highleyman, L | 1 |
| Piyathilake, CJ | 1 |
| Frost, AR | 1 |
| Bell, WC | 1 |
| Oelschlager, D | 1 |
| Weiss, H | 1 |
| Johanning, GL | 1 |
| Niveleau, A | 1 |
| Heimburger, DC | 1 |
| Grizzle, WE | 1 |
| Clarke, NR | 1 |
| Kelion, AD | 1 |
| Nixon, J | 1 |
| Hilton-Jones, D | 1 |
| Forfar, JC | 1 |
| Mazzi, R | 1 |
| Parisi, SG | 1 |
| Sarmati, L | 1 |
| Uccella, I | 1 |
| Nicastri, E | 1 |
| Carolo, G | 1 |
| Gatti, F | 1 |
| Concia, E | 1 |
| Andreoni, M | 1 |
| Wilcox, RD | 1 |
| Parsons, BL | 1 |
| Culp, SJ | 1 |
| Manjanatha, MG | 1 |
| Heflich, RH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Studies of the Ocular Complications of AIDS (SOCA)--HPMPC Peripheral CMV Retinitis Trial (HPCRT)[NCT00000142] | Phase 2/Phase 3 | 64 participants (Actual) | Interventional | 1994-04-30 | Completed | ||
| HPMPC (Cidofovir) Peripheral CMV Retinitis Trial Protocol[NCT00000799] | 100 participants | Interventional | Completed | ||||
| Studies of Ocular Complications of AIDS (SOCA)--Ganciclovir-Cidofovir CMV Retinitis Trial (GCCRT)[NCT00000143] | Phase 3 | 61 participants (Actual) | Interventional | 1997-05-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
(NCT00000142)
Timeframe: All patients enrolled will be followed until a common study closing date
| Intervention | participants (Number) | ||
|---|---|---|---|
| mortality | progression | va loss of 15 letters | |
| Cidofovir (High Dose) | 3 | 5 | 2 |
| Cidofovir (Low Dose) | 7 | 17 | 6 |
| Treatment Deferral | 6 | 20 | 4 |
(NCT00000143)
Timeframe: 3 years
| Intervention | participants (Number) |
|---|---|
| Ganciclovir Implant and Oral Ganciclovir | 31 |
| Cidofovir IV (Intravenous) | 30 |
2 reviews available for cytosine and Disease Exacerbation
| Article | Year |
|---|---|
Epigenetic profiles as defined signatures of xenobiotic exposure.
Topics: 5-Methylcytosine; Animals; Carcinogens; Chemical Safety; Chromatin; Cytosine; Disease Progression; D | 2014 |
Medical and surgical interventions for the treatment of usual-type vulval intraepithelial neoplasia.
Topics: Adult; Aminoquinolines; Antineoplastic Agents; Carcinoma in Situ; Cidofovir; Cytosine; Disease Progr | 2016 |
7 trials available for cytosine and Disease Exacerbation
| Article | Year |
|---|---|
Phase II study of troxacitabine (BCH-4556) in patients with advanced and/or metastatic renal cell carcinoma: a trial of the National Cancer Institute of Canada-Clinical Trials Group.
Topics: Aged; Antineoplastic Agents; Canada; Carcinoma, Renal Cell; Cytosine; Dioxolanes; Disease Progressio | 2003 |
[Anticytosine therapy for primary myelodysplastic syndrome].
Topics: Aged; Bone Marrow; Cytosine; Disease Progression; Erythrocyte Transfusion; Female; Hematologic Agent | 2003 |
Phase II study of troxacitabine in chemotherapy-naive patients with advanced cancer of the pancreas: gastrointestinal tumors.
Topics: Adult; Aged; Antineoplastic Agents; Body Weight; Cytosine; Dioxolanes; Disease Progression; Female; | 2005 |
Intravenous cidofovir for peripheral cytomegalovirus retinitis in patients with AIDS. A randomized, controlled trial.
Topics: Adolescent; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovir | 1997 |
Parenteral cidofovir for cytomegalovirus retinitis in patients with AIDS: the HPMPC peripheral cytomegalovirus retinitis trial. A randomized, controlled trial. Studies of Ocular complications of AIDS Research Group in Collaboration with the AIDS Clinical
Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Combined Modality Therapy | 1997 |
Parenteral cidofovir for cytomegalovirus retinitis in patients with AIDS: the HPMPC peripheral cytomegalovirus retinitis trial. A randomized, controlled trial. Studies of Ocular complications of AIDS Research Group in Collaboration with the AIDS Clinical
Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Combined Modality Therapy | 1997 |
Parenteral cidofovir for cytomegalovirus retinitis in patients with AIDS: the HPMPC peripheral cytomegalovirus retinitis trial. A randomized, controlled trial. Studies of Ocular complications of AIDS Research Group in Collaboration with the AIDS Clinical
Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Combined Modality Therapy | 1997 |
Parenteral cidofovir for cytomegalovirus retinitis in patients with AIDS: the HPMPC peripheral cytomegalovirus retinitis trial. A randomized, controlled trial. Studies of Ocular complications of AIDS Research Group in Collaboration with the AIDS Clinical
Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Combined Modality Therapy | 1997 |
Randomized, controlled study of the safety and efficacy of intravenous cidofovir for the treatment of relapsing cytomegalovirus retinitis in patients with AIDS.
Topics: Adolescent; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Creatinine; C | 1998 |
The ganciclovir implant plus oral ganciclovir versus parenteral cidofovir for the treatment of cytomegalovirus retinitis in patients with acquired immunodeficiency syndrome: The Ganciclovir Cidofovir Cytomegalovirus Retinitis Trial.
Topics: Administration, Oral; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cyt | 2001 |
43 other studies available for cytosine and Disease Exacerbation
| Article | Year |
|---|---|
Epigenetic signatures of methylated DNA cytosine in Alzheimer's disease.
Topics: 5-Methylcytosine; Aged; Alzheimer Disease; Biomarkers; Cytosine; Disease Progression; DNA; DNA Methy | 2019 |
CAG Repeat Size Influences the Progression Rate of Spinocerebellar Ataxia Type 3.
Topics: Adenine; Adult; Ataxin-3; Cytosine; Disease Progression; Female; Guanine; Humans; Machado-Joseph Dis | 2021 |
Cytosine methylation predicts renal function decline in American Indians.
Topics: Adult; Aged; Albuminuria; Apoptosis; Case-Control Studies; Cell Cycle; CpG Islands; Cytosine; Diabet | 2018 |
Aberrant DNA methylation of mTOR pathway genes promotes inflammatory activation of immune cells in diabetic kidney disease.
Topics: Adolescent; Adoptive Transfer; Adult; Aged; Animals; Azacitidine; Cytosine; Diabetic Nephropathies; | 2019 |
Kidney cytosine methylation changes improve renal function decline estimation in patients with diabetic kidney disease.
Topics: Aged; Case-Control Studies; CpG Islands; Cross-Sectional Studies; Cytosine; Diabetic Nephropathies; | 2019 |
Loss of 5-hydroxymethylcytosine and ten-eleven translocation 2 protein expression in malignant melanoma.
Topics: 5-Methylcytosine; Biomarkers, Tumor; Cytosine; Dioxygenases; Disease Progression; DNA-Binding Protei | 2013 |
Decrease of 5-hydroxymethylcytosine is associated with progression of hepatocellular carcinoma through downregulation of TET1.
Topics: 5-Methylcytosine; Animals; Blotting, Western; Carcinoma, Hepatocellular; Cell Line, Tumor; Cytosine; | 2013 |
Quantitative analysis of interdental Gingiva in patients with chronic periodontitis and transforming growth factor-β1 29C/T gene polymorphisms.
Topics: Adult; Alleles; Azo Compounds; Case-Control Studies; Chronic Periodontitis; Collagen; Coloring Agent | 2014 |
Global changes in DNA methylation and hydroxymethylation in Alzheimer's disease human brain.
Topics: 5-Methylcytosine; Aged; Aged, 80 and over; Alzheimer Disease; Astrocytes; Cytosine; Disease Progress | 2014 |
Genetic variants in AKT1 gene were associated with risk and survival of OSCC in Chinese Han Population.
Topics: Aged; Alleles; Carcinoma, Squamous Cell; China; Cohort Studies; Cytosine; Disease Progression; Ethni | 2015 |
TET2 repression by androgen hormone regulates global hydroxymethylation status and prostate cancer progression.
Topics: 5-Methylcytosine; Aged; Androgens; Animals; Blotting, Western; Cell Line, Tumor; Cell Proliferation; | 2015 |
Relationship between cytosine-adenine repeat polymorphism of ADAMTS9 gene and clinical and radiologic severity of knee osteoarthritis.
Topics: ADAMTS9 Protein; Adenine; Adult; Aged; Case-Control Studies; Chi-Square Distribution; Cytosine; Dise | 2018 |
Distinct evolution and dynamics of epigenetic and genetic heterogeneity in acute myeloid leukemia.
Topics: Adult; Alleles; CpG Islands; Cytosine; Disease Progression; DNA Methylation; Epigenesis, Genetic; Ev | 2016 |
Intermediate dose cidofovir does not cause additive nephrotoxicity in BK virus allograft nephropathy.
Topics: Adolescent; Adult; Antiviral Agents; BK Virus; Child; Child, Preschool; Cidofovir; Cohort Studies; C | 2008 |
Using biomarkers to stage disease progression in a lethal mousepox model treated with CMX001.
Topics: Alanine Transaminase; Animals; Antiviral Agents; Aspartate Aminotransferases; Biomarkers; Cell Line; | 2008 |
Interleukin-6 (G-174C) and tumour necrosis factor-alpha (G-308A) gene polymorphisms in geriatric patients with chronic periodontitis.
Topics: Adenine; Aged; Alleles; Alveolar Bone Loss; Chronic Periodontitis; Cytosine; Disease Progression; Fe | 2010 |
Intrafamilial clinical phenotypic heterogeneity with MAPT gene splice site IVS10+16C>T mutation.
Topics: Atrophy; Base Sequence; Brain; Brain Chemistry; Cytosine; Disease Progression; DNA; DNA Mutational A | 2009 |
Degrees of dysplasia and the use of cidofovir in patients with recurrent respiratory papillomatosis.
Topics: Adult; Aged; Biopsy; Cidofovir; Cytosine; Disease Progression; Female; Follow-Up Studies; Humans; Ma | 2010 |
The antimicrobial peptide DEFB1 is associated with caries.
Topics: Adenine; Adolescent; Adult; Aged; Aged, 80 and over; Aggressive Periodontitis; Alleles; Antimicrobia | 2010 |
MMP3 and TIMP1 variants contribute to chronic periodontitis and may be implicated in disease progression.
Topics: Adult; Brazil; Case-Control Studies; Chromosomes, Human, Pair 11; Chromosomes, Human, X; Chronic Per | 2012 |
Epigenetic modification of liver mitochondrial DNA is associated with histological severity of nonalcoholic fatty liver disease.
Topics: Adult; Biopsy; Case-Control Studies; Cytosine; Disease Progression; DNA (Cytosine-5-)-Methyltransfer | 2013 |
Increased 5-methylcytosine and decreased 5-hydroxymethylcytosine levels are associated with reduced striatal A2AR levels in Huntington's disease.
Topics: 5-Methylcytosine; 5' Untranslated Regions; Adult; Aged; Aged, 80 and over; Animals; Corpus Striatum; | 2013 |
Integrin beta3 Leu33Pro homozygosity and risk of cancer.
Topics: Adult; Aged; Aged, 80 and over; Alleles; Animals; Cytosine; Denmark; Disease Progression; Female; Ge | 2003 |
G protein beta3 subunit C825T polymorphism in primary IgA nephropathy.
Topics: Adult; Alleles; Cytosine; Disease Progression; Female; Gene Frequency; Genotype; Glomerulonephritis, | 2004 |
The impact of CAG repeats in exon 1 of the androgen receptor on disease progression after prostatectomy.
Topics: Adenine; Age Factors; Aged; Black People; Cytosine; Disease Progression; Exons; Genotype; Guanine; H | 2005 |
High anti-double-stranded DNA antibodies and progressive multifocal leukoencephalopathy in a patient with systemic lupus erythematosus.
Topics: Antibodies, Anti-Idiotypic; Cidofovir; Cytosine; Disease Progression; DNA; Fatal Outcome; Female; Hu | 2005 |
Transforming growth factor-beta1 SNPs: genetic and phenotypic correlations in progressive kidney insufficiency.
Topics: Adult; Aged; Aged, 80 and over; Arginine; Case-Control Studies; Cytosine; Disease Progression; Femal | 2005 |
Cidofovir and the black box warning.
Topics: Animals; Antineoplastic Agents; Cidofovir; Cytosine; Disease Progression; Drug Labeling; Humans; Lar | 2005 |
Case of progressive dysplasia concomitant with intralesional cidofovir administration for recurrent respiratory papillomatosis.
Topics: Adult; Antineoplastic Agents; Cidofovir; Cytosine; Disease Progression; Female; Humans; Injections, | 2005 |
CXCL10 haplotypes and multiple sclerosis: association and correlation with clinical course.
Topics: Adolescent; Adult; Aged; Chemokine CXCL10; Chemokines, CXC; Cytosine; Disease Progression; Exons; Fe | 2007 |
Methylenetetrahydrofolate reductase C677T mutation and nonalcoholic fatty liver disease.
Topics: Adult; Case-Control Studies; Cytosine; Disease Progression; Fatty Liver; Female; Gene Frequency; Gen | 2007 |
The 212A variant of the APJ receptor gene for the endogenous inotrope apelin is associated with slower heart failure progression in idiopathic dilated cardiomyopathy.
Topics: Adenine; Adult; Alleles; Apelin; Apelin Receptors; Cardiomyopathy, Dilated; Cytosine; Disease Progre | 2007 |
Treatment of cytomegalovirus retinitis with intravitreous cidofovir in patients with AIDS. A preliminary report.
Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Infection | 1996 |
Intravitreal cidofovir for the maintenance treatment of cytomegalovirus retinitis.
Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis | 1996 |
Cidofovir for AIDS-related retinitis.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytos | 1996 |
Low-dose intravitreal cidofovir (HPMPC) therapy of cytomegalovirus retinitis in patients with acquired immune deficiency syndrome.
Topics: Adolescent; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovir | 1997 |
Tumour necrosis factor alpha gene polymorphisms in rheumatoid arthritis: association with susceptibility to, or severity of, disease?
Topics: Adenine; Adult; Aged; Alleles; Arthritis, Rheumatoid; Base Sequence; Case-Control Studies; Cytosine; | 1997 |
Fomivirsen.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Clinical Trials as Topic; Cytome | 1998 |
Altered global methylation of DNA: an epigenetic difference in susceptibility for lung cancer is associated with its progression.
Topics: 5-Methylcytosine; Antibodies, Monoclonal; Bronchi; Carcinoma, Squamous Cell; Cytosine; Disease Progr | 2001 |
Does cytosine-thymine-guanine (CTG) expansion size predict cardiac events and electrocardiographic progression in myotonic dystrophy?
Topics: Adult; Aged; Arrhythmias, Cardiac; Cytosine; Death, Sudden, Cardiac; Defibrillators, Implantable; Di | 2001 |
Efficacy of cidofovir on human herpesvirus 8 viraemia and Kaposi's sarcoma progression in two patients with AIDS.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytosine; Disease Progression; D | 2001 |
Cidofovir: progress in the treatment of progressive multifocal encephalopathy (PML)?
Topics: AIDS-Related Opportunistic Infections; Antiretroviral Therapy, Highly Active; Antiviral Agents; CD4 | 2002 |
Occurrence of H-ras codon 61 CAA to AAA mutation during mouse liver tumor progression.
Topics: Adenine; Animals; Benzo(a)pyrene; Carcinogens; Coal Tar; Codon; Cytosine; Disease Progression; Genes | 2002 |