cytosine has been researched along with Diabetes Mellitus, Type 2 in 26 studies
Diabetes Mellitus, Type 2: A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Novel biomarkers of type 2 diabetes (T2D) and response to preventative treatment in individuals with similar clinical risk may highlight metabolic pathways that are important in disease development." | 2.90 | Metabolite Profiles of Incident Diabetes and Heterogeneity of Treatment Effect in the Diabetes Prevention Program. ( Chen, ZZ; Clish, C; Dagogo-Jack, S; Ferguson, JF; Florez, JC; Gerszten, RE; Hamman, RF; Heckman-Stoddard, BM; Knowler, WC; Lee, CG; Liu, J; Mather, KJ; Morningstar, J; Perreault, L; Temprosa, M; Wang, TJ, 2019) |
| "The overall OR (95% CI) of type 2 diabetes was 0." | 2.44 | Association between the T-381C polymorphism of the brain natriuretic peptide gene and risk of type 2 diabetes in human populations. ( Amouyel, P; Arveiler, D; Cottel, D; de Groote, P; Ferrières, J; Groves, CJ; Hattersley, AT; Hitman, GA; McCarthy, MI; Meirhaeghe, A; Sandhu, MS; Walker, M; Wareham, NJ, 2007) |
| "Metabolic syndrome was diagnosed on modified National Cholesterol Education Program Adult Treatment Panel III guidelines, using body mass index (BMI) instead of waist circumference." | 1.33 | Association of mitochondrial deoxyribonucleic acid 16189 variant (T->C transition) with metabolic syndrome in Chinese adults. ( Chen, IY; Chen, JF; Chen, MH; Chen, SD; Eng, HL; Lee, CF; Lin, TK; Liou, CW; Liu, RT; Wang, PW; Wei, YH; Weng, SW, 2005) |
| "We selected 15 families with MODY for this project." | 1.31 | Identification of a new mutation in the hepatocyte nuclear factor-1alpha gene in a Polish family with early-onset type 2 diabetes mellitus. ( Cyganek, K; Frey, J; Galicka-Stankowska, D; Klupa, T; Malecki, MT; Sieradzki, J; Wanic, K, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (7.69) | 18.2507 |
| 2000's | 18 (69.23) | 29.6817 |
| 2010's | 3 (11.54) | 24.3611 |
| 2020's | 3 (11.54) | 2.80 |
| Authors | Studies |
|---|---|
| Jazayeri, M | 1 |
| Eftekhari-Yazdi, P | 1 |
| Sadighi Gilani, MA | 1 |
| Sharafi, M | 1 |
| Shahverdi, A | 1 |
| Alka, K | 1 |
| Mohammad, G | 1 |
| Kowluru, RA | 1 |
| Ma, J | 3 |
| Joehanes, R | 3 |
| Liu, C | 3 |
| Keshawarz, A | 3 |
| Hwang, SJ | 3 |
| Bui, H | 3 |
| Tejada, B | 3 |
| Sooda, M | 3 |
| Munson, PJ | 3 |
| Demirkale, CY | 3 |
| Courchesne, P | 3 |
| Heard-Costa, NL | 3 |
| Pitsillides, AN | 3 |
| Feolo, M | 3 |
| Sharopova, N | 3 |
| Vasan, RS | 3 |
| Huan, T | 3 |
| Levy, D | 3 |
| Chen, ZZ | 1 |
| Liu, J | 1 |
| Morningstar, J | 1 |
| Heckman-Stoddard, BM | 1 |
| Lee, CG | 1 |
| Dagogo-Jack, S | 1 |
| Ferguson, JF | 1 |
| Hamman, RF | 1 |
| Knowler, WC | 2 |
| Mather, KJ | 1 |
| Perreault, L | 1 |
| Florez, JC | 1 |
| Wang, TJ | 1 |
| Clish, C | 1 |
| Temprosa, M | 1 |
| Gerszten, RE | 1 |
| Spallotta, F | 1 |
| Cencioni, C | 1 |
| Atlante, S | 1 |
| Garella, D | 1 |
| Cocco, M | 1 |
| Mori, M | 1 |
| Mastrocola, R | 1 |
| Kuenne, C | 1 |
| Guenther, S | 1 |
| Nanni, S | 1 |
| Azzimato, V | 1 |
| Zukunft, S | 1 |
| Kornberger, A | 1 |
| Sürün, D | 1 |
| Schnütgen, F | 1 |
| von Melchner, H | 1 |
| Di Stilo, A | 1 |
| Aragno, M | 1 |
| Braspenning, M | 1 |
| van Criekinge, W | 1 |
| De Blasio, MJ | 1 |
| Ritchie, RH | 1 |
| Zaccagnini, G | 1 |
| Martelli, F | 1 |
| Farsetti, A | 1 |
| Fleming, I | 1 |
| Braun, T | 1 |
| Beiras-Fernandez, A | 1 |
| Botta, B | 1 |
| Collino, M | 1 |
| Bertinaria, M | 1 |
| Zeiher, AM | 1 |
| Gaetano, C | 1 |
| López, NJ | 1 |
| Valenzuela, CY | 1 |
| Jara, L | 1 |
| Xia, JF | 1 |
| Hu, P | 1 |
| Liang, QL | 1 |
| Zou, TT | 1 |
| Wang, YM | 1 |
| Luo, GA | 1 |
| Doney, A | 1 |
| Fischer, B | 2 |
| Frew, D | 1 |
| Cumming, A | 1 |
| Flavell, DM | 1 |
| World, M | 1 |
| Montgomery, HE | 1 |
| Boyle, D | 1 |
| Morris, A | 1 |
| Palmer, CN | 2 |
| Vozarova, B | 1 |
| Fernández-Real, JM | 1 |
| Gallart, L | 1 |
| Hanson, RL | 1 |
| Gruber, JD | 1 |
| Ricart, W | 1 |
| Vendrell, J | 1 |
| Richart, C | 1 |
| Tataranni, PA | 1 |
| Wolford, JK | 1 |
| Malecki, MT | 2 |
| Klupa, T | 2 |
| Wolkow, P | 1 |
| Bochenski, J | 1 |
| Wanic, K | 2 |
| Sieradzki, J | 2 |
| Cao, H | 1 |
| van der Veer, E | 1 |
| Ban, MR | 1 |
| Hanley, AJ | 1 |
| Zinman, B | 1 |
| Harris, SB | 1 |
| Young, TK | 1 |
| Pickering, JG | 1 |
| Hegele, RA | 1 |
| Möhlig, M | 1 |
| Boeing, H | 1 |
| Spranger, J | 1 |
| Osterhoff, M | 1 |
| Kroke, A | 1 |
| Fisher, E | 1 |
| Bergmann, MM | 1 |
| Ristow, M | 1 |
| Hoffmann, K | 1 |
| Pfeiffer, AF | 1 |
| Doney, AS | 1 |
| Leese, G | 1 |
| Morris, AD | 1 |
| Tavares, V | 1 |
| Hirata, RD | 1 |
| Rodrigues, AC | 1 |
| Monte, O | 1 |
| Salles, JE | 1 |
| Scallissi, N | 1 |
| Speranza, AC | 1 |
| Gomes, S | 1 |
| Hirata, MH | 1 |
| Nakagawa, T | 1 |
| Furuta, H | 1 |
| Sanke, T | 1 |
| Sakagashira, S | 1 |
| Shimomura, H | 1 |
| Shimajiri, Y | 1 |
| Hanabusa, T | 1 |
| Nishi, M | 1 |
| Sasaki, H | 1 |
| Nanjo, K | 1 |
| Weng, SW | 1 |
| Liou, CW | 1 |
| Lin, TK | 1 |
| Wei, YH | 1 |
| Lee, CF | 1 |
| Eng, HL | 1 |
| Chen, SD | 1 |
| Liu, RT | 1 |
| Chen, JF | 1 |
| Chen, IY | 1 |
| Chen, MH | 1 |
| Wang, PW | 1 |
| Freathy, RM | 1 |
| Weedon, MN | 1 |
| Shields, B | 1 |
| Hitman, GA | 2 |
| Walker, M | 2 |
| McCarthy, MI | 2 |
| Hattersley, AT | 2 |
| Frayling, TM | 1 |
| Dworacka, M | 1 |
| Winiarska, H | 1 |
| Jagodziński, PP | 1 |
| Eroglu, Z | 1 |
| Erdogan, M | 1 |
| Tetik, A | 1 |
| Karadeniz, M | 1 |
| Cetinalp, S | 1 |
| Kosova, B | 1 |
| Gunduz, C | 1 |
| Ozgen, AG | 1 |
| Yilmaz, C | 1 |
| Meirhaeghe, A | 1 |
| Sandhu, MS | 1 |
| de Groote, P | 1 |
| Cottel, D | 1 |
| Arveiler, D | 1 |
| Ferrières, J | 1 |
| Groves, CJ | 1 |
| Wareham, NJ | 1 |
| Amouyel, P | 1 |
| Tarnai, I | 1 |
| Csordás, M | 1 |
| Sükei, E | 1 |
| Shemirani, AH | 1 |
| Káplár, M | 1 |
| Góth, L | 1 |
| Walston, J | 1 |
| Lowe, A | 1 |
| Silver, K | 1 |
| Yang, Y | 1 |
| Bodkin, NL | 1 |
| Hansen, BC | 1 |
| Shuldiner, AR | 1 |
| Yang, T | 1 |
| Lam, CW | 1 |
| Tsang, MW | 1 |
| Tong, SF | 1 |
| Chan, LY | 1 |
| Kam, GY | 1 |
| Poon, PM | 1 |
| Wu, XQ | 1 |
| Pang, CP | 1 |
| Gill-Randall, R | 1 |
| Sherratt, EJ | 1 |
| Thomas, AW | 1 |
| Gagg, JW | 1 |
| Lee, A | 1 |
| Alcolado, JC | 1 |
| Frey, J | 1 |
| Cyganek, K | 1 |
| Galicka-Stankowska, D | 1 |
| Stridsberg, M | 1 |
| Wilander, E | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Genetics of Diabetes Audit and Research in Tayside Scotland (DOLORisk Dundee)[NCT02783469] | 1,915 participants (Actual) | Observational | 2004-10-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for cytosine and Diabetes Mellitus, Type 2
| Article | Year |
|---|---|
Association between the T-381C polymorphism of the brain natriuretic peptide gene and risk of type 2 diabetes in human populations.
Topics: Adult; Aged; Animals; Case-Control Studies; Chlorocebus aethiops; COS Cells; Cytosine; Diabetes Mell | 2007 |
Islet amyloid polypeptide (IAPP). A short review.
Topics: Animals; Cytosine; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Humans; Pancreatic Neoplasm | 1991 |
1 trial available for cytosine and Diabetes Mellitus, Type 2
| Article | Year |
|---|---|
Metabolite Profiles of Incident Diabetes and Heterogeneity of Treatment Effect in the Diabetes Prevention Program.
Topics: Adult; Aged; Biomarkers; Cytosine; Diabetes Mellitus, Type 2; Female; Humans; Incidence; Life Style; | 2019 |
23 other studies available for cytosine and Diabetes Mellitus, Type 2
| Article | Year |
|---|---|
Epigenetic modifications at DMRs of imprinting genes in sperm of type 2 diabetic men.
Topics: Chromatin; Cytosine; Diabetes Mellitus, Type 2; DNA Methylation; Genomic Imprinting; Humans; Male; S | 2022 |
Regulation of serine palmitoyl-transferase and Rac1-Nox2 signaling in diabetic retinopathy.
Topics: Animals; Ceramides; Cytosine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic R | 2022 |
Elucidating the genetic architecture of DNA methylation to identify promising molecular mechanisms of disease.
Topics: Coronary Artery Disease; COVID-19; CpG Islands; Cytosine; Diabetes Mellitus, Type 2; DNA Methylation | 2022 |
Elucidating the genetic architecture of DNA methylation to identify promising molecular mechanisms of disease.
Topics: Coronary Artery Disease; COVID-19; CpG Islands; Cytosine; Diabetes Mellitus, Type 2; DNA Methylation | 2022 |
Elucidating the genetic architecture of DNA methylation to identify promising molecular mechanisms of disease.
Topics: Coronary Artery Disease; COVID-19; CpG Islands; Cytosine; Diabetes Mellitus, Type 2; DNA Methylation | 2022 |
Elucidating the genetic architecture of DNA methylation to identify promising molecular mechanisms of disease.
Topics: Coronary Artery Disease; COVID-19; CpG Islands; Cytosine; Diabetes Mellitus, Type 2; DNA Methylation | 2022 |
Elucidating the genetic architecture of DNA methylation to identify promising molecular mechanisms of disease.
Topics: Coronary Artery Disease; COVID-19; CpG Islands; Cytosine; Diabetes Mellitus, Type 2; DNA Methylation | 2022 |
Elucidating the genetic architecture of DNA methylation to identify promising molecular mechanisms of disease.
Topics: Coronary Artery Disease; COVID-19; CpG Islands; Cytosine; Diabetes Mellitus, Type 2; DNA Methylation | 2022 |
Elucidating the genetic architecture of DNA methylation to identify promising molecular mechanisms of disease.
Topics: Coronary Artery Disease; COVID-19; CpG Islands; Cytosine; Diabetes Mellitus, Type 2; DNA Methylation | 2022 |
Elucidating the genetic architecture of DNA methylation to identify promising molecular mechanisms of disease.
Topics: Coronary Artery Disease; COVID-19; CpG Islands; Cytosine; Diabetes Mellitus, Type 2; DNA Methylation | 2022 |
Elucidating the genetic architecture of DNA methylation to identify promising molecular mechanisms of disease.
Topics: Coronary Artery Disease; COVID-19; CpG Islands; Cytosine; Diabetes Mellitus, Type 2; DNA Methylation | 2022 |
Stable Oxidative Cytosine Modifications Accumulate in Cardiac Mesenchymal Cells From Type2 Diabetes Patients: Rescue by α-Ketoglutarate and TET-TDG Functional Reactivation.
Topics: Animals; Cells, Cultured; Cytosine; Diabetes Mellitus, Type 2; Enzyme Inhibitors; HEK293 Cells; Huma | 2018 |
Interleukin-1 gene cluster polymorphisms associated with periodontal disease in type 2 diabetes.
Topics: Adult; Age Factors; Aged; Alleles; Case-Control Studies; Chronic Periodontitis; Cytosine; Dental Pla | 2009 |
Correlations of creatine and six related pyrimidine metabolites and diabetic nephropathy in Chinese type 2 diabetic patients.
Topics: Aged; Chromatography, High Pressure Liquid; Creatine; Cytidine; Cytosine; Deoxyuridine; Diabetes Mel | 2010 |
Haplotype analysis of the PPARgamma Pro12Ala and C1431T variants reveals opposing associations with body weight.
Topics: Adult; Alanine; Amino Acid Substitution; Body Mass Index; Body Weight; Cytosine; Diabetes Mellitus, | 2002 |
The interleukin-6 (-174) G/C promoter polymorphism is associated with type-2 diabetes mellitus in Native Americans and Caucasians.
Topics: Adult; Aged; Alleles; Asian People; Case-Control Studies; Cytosine; Diabetes Mellitus, Type 2; Femal | 2003 |
Association study of the vitamin D: 1alpha-hydroxylase (CYP1alpha) gene and type 2 diabetes mellitus in a Polish population.
Topics: Cytosine; Diabetes Mellitus; Diabetes Mellitus, Type 2; Genetic Markers; Genotype; Humans; Introns; | 2003 |
Promoter polymorphism in PCK1 (phosphoenolpyruvate carboxykinase gene) associated with type 2 diabetes mellitus.
Topics: Adult; Base Sequence; Canada; Cytosine; Diabetes Mellitus, Type 2; DNA; Female; Genetic Variation; G | 2004 |
Body mass index and C-174G interleukin-6 promoter polymorphism interact in predicting type 2 diabetes.
Topics: Body Mass Index; Case-Control Studies; Cohort Studies; Cytosine; Diabetes Mellitus, Type 2; Female; | 2004 |
Cardiovascular risk in type 2 diabetes is associated with variation at the PPARG locus: a Go-DARTS study.
Topics: Age Factors; Alanine; Alleles; Amino Acid Substitution; Cardiovascular Diseases; Cohort Studies; Cyt | 2004 |
Effect of the peroxisome proliferator-activated receptor-gamma C161T polymorphism on lipid profile in Brazilian patients with Type 2 diabetes mellitus.
Topics: Adult; Aged; Base Sequence; Brazil; Case-Control Studies; Cytosine; Diabetes Mellitus, Type 2; Femal | 2005 |
Molecular scanning of the betacellulin gene for mutations in type 2 diabetic patients.
Topics: Aged; Amino Acid Substitution; Base Sequence; Betacellulin; Cysteine; Cytosine; Diabetes Mellitus, T | 2005 |
Association of mitochondrial deoxyribonucleic acid 16189 variant (T->C transition) with metabolic syndrome in Chinese adults.
Topics: Aged; Asian People; Blood Glucose; Case-Control Studies; Cytosine; Diabetes Mellitus, Type 2; DNA, M | 2005 |
Functional variation in VEGF is not associated with type 2 diabetes in a United Kingdom Caucasian population.
Topics: Adenine; Adult; Case-Control Studies; Cytosine; Diabetes Mellitus, Type 2; Female; Gene Frequency; G | 2006 |
Impact of the sulfonylurea receptor 1 (SUR1) exon 16-3c/t polymorphism on acute hyperglycaemia in type 2 diabetic patients.
Topics: Age of Onset; ATP-Binding Cassette Transporters; Body Mass Index; Cytosine; Diabetes Mellitus, Type | 2007 |
The relationship of the methylenetetrahydrofolate reductase C677T gene polymorphism in Turkish type 2 diabetic patients with and without nephropathy.
Topics: Aged; Cytosine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; DNA; DNA Primers; Gene Frequency; | 2007 |
Effect of C111T polymorphism in exon 9 of the catalase gene on blood catalase activity in different types of diabetes mellitus.
Topics: Adult; Catalase; Cytosine; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetes, Gestation | 2007 |
The beta3-adrenergic receptor in the obesity and diabetes prone rhesus monkey is very similar to human and contains arginine at codon 64.
Topics: Amino Acid Sequence; Animals; Arginine; Base Sequence; Codon; Cytosine; Diabetes Mellitus, Type 2; D | 1997 |
Novel single nucleotide polymorphisms (3203A>G and 3204C>T) in the 3' end of the mitochondrial 16S rRNA gene.
Topics: 3' Untranslated Regions; Adenine; Base Sequence; Cytosine; Diabetes Mellitus, Type 2; Guanine; Human | 2000 |
Analysis of a polycytosine tract and heteroplasmic length variation in the mitochondrial DNA D-loop of patients with diabetes, MELAS syndrome and race-matched controls.
Topics: Adult; Cytosine; Diabetes Mellitus, Type 2; DNA, Mitochondrial; Genetic Variation; Humans; Leukocyte | 2001 |
Identification of a new mutation in the hepatocyte nuclear factor-1alpha gene in a Polish family with early-onset type 2 diabetes mellitus.
Topics: Adolescent; Adult; Cytosine; Diabetes Mellitus, Type 2; DNA-Binding Proteins; Exons; Female; Gene Fr | 2001 |