Page last updated: 2024-10-17

cytosine and Dementia Praecox

cytosine has been researched along with Dementia Praecox in 27 studies

Research Excerpts

ExcerptRelevanceReference
"The impact of genetic polymorphism of CYP1A2 that are related to the induction of the isozyme on the plasma levels of haloperidol (HAL) in 40 male smokers with schizophrenia was investigated."7.71Lack of impact of CYP1A2 genetic polymorphism (C/A polymorphism at position 734 in intron 1 and G/A polymorphism at position -2964 in the 5'-flanking region of CYP1A2) on the plasma concentration of haloperidol in smoking male Japanese with schizophrenia. ( Hirokane, G; Morita, S; Okawa, M; Shimoda, K; Someya, T; Takahashi, S; Yokono, A, 2002)
"The down regulation of glutamic acid decarboxylase67 (GAD1), reelin (RELN), and BDNF expression in brain of schizophrenia (SZ) and bipolar (BP) disorder patients is associated with overexpression of DNA methyltransferase1 (DNMT1) and ten-eleven translocase methylcytosine dioxygenase1 (TET1)."3.81DNA-methyltransferase1 (DNMT1) binding to CpG rich GABAergic and BDNF promoters is increased in the brain of schizophrenia and bipolar disorder patients. ( Dong, E; Grayson, DR; Guidotti, A; Ruzicka, WB, 2015)
"Recent advances in schizophrenia (SZ) research indicate that the telencephalic gamma-aminobutyric acid (GABA)ergic neurotransmission deficit associated with this psychiatric disorder probably is mediated by the hypermethylation of the glutamic acid decarboxylase 67 (GAD(67)), reelin and other GABAergic promoters."3.75Characterization of the action of antipsychotic subtypes on valproate-induced chromatin remodeling. ( Costa, E; Dong, E; Grayson, DR; Guidotti, A; Kundakovic, M; Satta, R, 2009)
"The impact of genetic polymorphism of CYP1A2 that are related to the induction of the isozyme on the plasma levels of haloperidol (HAL) in 40 male smokers with schizophrenia was investigated."3.71Lack of impact of CYP1A2 genetic polymorphism (C/A polymorphism at position 734 in intron 1 and G/A polymorphism at position -2964 in the 5'-flanking region of CYP1A2) on the plasma concentration of haloperidol in smoking male Japanese with schizophrenia. ( Hirokane, G; Morita, S; Okawa, M; Shimoda, K; Someya, T; Takahashi, S; Yokono, A, 2002)
"Patients with schizophrenia have a higher risk for developing diabetes than the general population."1.32Distribution of the serotonin 2C (5HT2C) receptor gene -759C/T polymorphism in patients with schizophrenia and normal controls. ( Ellingrod, VL; Miller, D; Perry, PJ; Ringold, JC, 2004)

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.70)18.7374
1990's4 (14.81)18.2507
2000's16 (59.26)29.6817
2010's6 (22.22)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Swathy, B1
Saradalekshmi, KR1
Nair, IV1
Nair, C1
Banerjee, M1
Oh, G1
Koncevičius, K1
Ebrahimi, S1
Carlucci, M1
Groot, DE1
Nair, A1
Zhang, A1
Kriščiūnas, A1
Oh, ES1
Labrie, V1
Wong, AHC1
Gordevičius, J1
Jia, P1
Susic, M1
Petronis, A1
Dong, E3
Ruzicka, WB1
Grayson, DR4
Guidotti, A4
Wang, JY1
Jia, CX1
Lian, Y1
Sun, SH1
Lyu, M1
Wu, A1
Murphy, BC2
O'Reilly, RL2
Singh, SM3
Kundakovic, M2
Satta, R1
Costa, E2
Chen, Y2
McDonald, PP1
O'reilly, R1
Abdolmaleky, HM1
Yaqubi, S1
Papageorgis, P1
Lambert, AW1
Ozturk, S1
Sivaraman, V1
Thiagalingam, S1
Kampman, O1
Anttila, S1
Illi, A1
Lehtimäki, T1
Mattila, KM1
Roivas, M1
Leinonen, E1
Kikuchi, M1
Yamada, K1
Toyota, T1
Yoshikawa, T1
Ellingrod, VL1
Miller, D1
Ringold, JC1
Perry, PJ1
Tan, EC1
Chong, SA1
Lim, LC2
Chan, AO1
Teo, YY1
Tan, CH1
Mahendran, R1
Hong, CJ1
Liu, HC1
Liu, TY1
Liao, DL1
Tsai, SJ1
Jia, X1
Sharma, RP1
Mitchell, CP1
Müller, DJ1
De Luca, V1
Sicard, T1
King, N1
Hwang, R1
Volavka, J1
Czobor, P1
Sheitman, BB1
Lindenmayer, JP1
Citrome, L1
McEvoy, JP1
Lieberman, JA1
Meltzer, HY1
Kennedy, JL1
Zhang, AP1
Yu, J1
Liu, JX1
Zhang, HY1
Du, YY1
Zhu, JD1
He, G1
Li, XW1
Gu, NF1
Feng, GY1
He, L1
Lafuente, A1
Bernardo, M1
Mas, S1
Crescenti, A1
Aparici, M1
Gassó, P1
Goti, J1
Sanchez, V1
Catalan, R1
Carne, X1
Coon, H1
Hoff, M1
Holik, J1
Delisi, LE1
Crowe, T1
Freedman, R1
Shields, G1
Boccio, AM1
Lerman, M1
Gershon, ES1
Jönsson, E1
Brené, S1
Lindblad, K1
Sharara, S1
Sedvall, G1
Schalling, M1
Spurlock, G1
Heils, A1
Holmans, P1
Williams, J1
D'Souza, UM1
Cardno, A1
Murphy, KC1
Jones, L1
Buckland, PR1
McGuffin, P1
Lesch, KP1
Owen, MJ1
Kunugi, H1
Fukuda, R1
Hattori, M1
Kato, T1
Tatsumi, M1
Sakai, T1
Hirose, T1
Nanko, S1
Joober, R1
Benkelfat, C1
Lal, S1
Bloom, D1
Labelle, A1
Lalonde, P1
Turecki, G1
Rozen, R1
Rouleau, GA1
Ujike, H1
Yamamoto, A1
Tanaka, Y1
Takehisa, Y1
Takaki, M1
Taked, T1
Kodama, M1
Kuroda, S1
Shimoda, K1
Someya, T1
Morita, S1
Hirokane, G1
Yokono, A1
Takahashi, S1
Okawa, M1
Tay, CH1
Chew, WL1

Reviews

2 reviews available for cytosine and Dementia Praecox

ArticleYear
Association of the HTR2A 102T/C polymorphism with attempted suicide: a meta-analysis.
    Psychiatric genetics, 2015, Volume: 25, Issue:4

    Topics: Cytosine; Genetic Association Studies; Genotype; Humans; Polymorphism, Single Nucleotide; Receptor,

2015
From trans-methylation to cytosine methylation: evolution of the methylation hypothesis of schizophrenia.
    Epigenetics, 2009, Apr-01, Volume: 4, Issue:3

    Topics: Animals; Brain; Cytosine; Disease Models, Animal; DNA Methylation; Epigenesis, Genetic; Evolution, M

2009

Other Studies

25 other studies available for cytosine and Dementia Praecox

ArticleYear
Understanding the influence of antipsychotic drugs on global methylation events and its relevance in treatment response.
    Epigenomics, 2018, Volume: 10, Issue:3

    Topics: 5-Methylcytosine; Adult; Antipsychotic Agents; Case-Control Studies; Clozapine; Cytosine; DNA; DNA (

2018
Circadian oscillations of cytosine modification in humans contribute to epigenetic variability, aging, and complex disease.
    Genome biology, 2019, 01-03, Volume: 20, Issue:1

    Topics: Aging; Circadian Rhythm; Cytosine; Epigenesis, Genetic; Humans; Leukemia, Lymphocytic, Chronic, B-Ce

2019
DNA-methyltransferase1 (DNMT1) binding to CpG rich GABAergic and BDNF promoters is increased in the brain of schizophrenia and bipolar disorder patients.
    Schizophrenia research, 2015, Volume: 167, Issue:1-3

    Topics: Aged; Aged, 80 and over; Analysis of Variance; Bipolar Disorder; Brain; Brain-Derived Neurotrophic F

2015
DNA methylation and mRNA expression of SYN III, a candidate gene for schizophrenia.
    BMC medical genetics, 2008, Dec-22, Volume: 9

    Topics: Animals; Brain; CpG Islands; Cytosine; DNA; DNA Methylation; Gene Expression; Genetic Predisposition

2008
Characterization of the action of antipsychotic subtypes on valproate-induced chromatin remodeling.
    Trends in pharmacological sciences, 2009, Volume: 30, Issue:2

    Topics: Animals; Antipsychotic Agents; Cell Adhesion Molecules, Neuronal; Chromatin Assembly and Disassembly

2009
Methylation analysis of the NOTCH4 -25 C/T polymorphism in schizophrenia.
    Psychiatric genetics, 2011, Volume: 21, Issue:1

    Topics: Base Sequence; Cytosine; DNA Methylation; DNA Mutational Analysis; Humans; Male; Middle Aged; Molecu

2011
Epigenetic dysregulation of HTR2A in the brain of patients with schizophrenia and bipolar disorder.
    Schizophrenia research, 2011, Volume: 129, Issue:2-3

    Topics: Bipolar Disorder; Cell Adhesion Molecules, Neuronal; Chi-Square Distribution; Cytosine; DNA Methylat

2011
Dopamine receptor D2 -141C Insertion/Deletion polymorphism in a Finnish population with schizophrenia.
    Psychiatry research, 2003, Nov-01, Volume: 121, Issue:1

    Topics: Alleles; Chromosome Deletion; Cross-Cultural Comparison; Cytosine; Europe; Finland; Gene Frequency;

2003
C18orf1 located on chromosome 18p11.2 may confer susceptibility to schizophrenia.
    Journal of medical and dental sciences, 2003, Volume: 50, Issue:3

    Topics: Adult; Alleles; Case-Control Studies; Centromere; Chromosomes, Human, Pair 18; Cytosine; Exons; Fema

2003
Distribution of the serotonin 2C (5HT2C) receptor gene -759C/T polymorphism in patients with schizophrenia and normal controls.
    Psychiatric genetics, 2004, Volume: 14, Issue:2

    Topics: Cytosine; Female; Genotype; Humans; Iowa; Male; Polymorphism, Single Nucleotide; Receptor, Serotonin

2004
Genetic analysis of the thermolabile methylenetetrahydrofolate reductase variant in schizophrenia and mood disorders.
    Psychiatric genetics, 2004, Volume: 14, Issue:4

    Topics: Adult; Alleles; Cytosine; Demography; Depressive Disorder; DNA; Female; Gene Frequency; Genetic Vari

2004
Site-specific cytosine methylation in S-COMT promoter in 31 brain regions with implications for studies involving schizophrenia.
    American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 2005, Feb-05, Volume: 133B, Issue:1

    Topics: Adult; Base Sequence; Brain; Catechol O-Methyltransferase; CpG Islands; Cytosine; DNA; DNA Methylati

2005
Association studies of the adenosine A2a receptor (1976T > C) genetic polymorphism in Parkinson's disease and schizophrenia.
    Journal of neural transmission (Vienna, Austria : 1996), 2005, Volume: 112, Issue:11

    Topics: Age Distribution; Age of Onset; Aged; Asian People; Base Sequence; Brain; Brain Chemistry; Cytosine;

2005
Reelin promoter hypermethylation in schizophrenia.
    Proceedings of the National Academy of Sciences of the United States of America, 2005, Jun-28, Volume: 102, Issue:26

    Topics: Binding, Competitive; Cell Adhesion Molecules, Neuronal; CpG Islands; Cytosine; DNA; DNA Methylation

2005
Suggestive association between the C825T polymorphism of the G-protein beta3 subunit gene (GNB3) and clinical improvement with antipsychotics in schizophrenia.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2005, Volume: 15, Issue:5

    Topics: Adult; Analysis of Variance; Antipsychotic Agents; Cytosine; Female; Heterotrimeric GTP-Binding Prot

2005
The DNA methylation profile within the 5'-regulatory region of DRD2 in discordant sib pairs with schizophrenia.
    Schizophrenia research, 2007, Volume: 90, Issue:1-3

    Topics: 5' Flanking Region; Adult; Base Pairing; CpG Islands; Cytosine; DNA Methylation; DNA-Cytosine Methyl

2007
-141C Ins/Del polymorphism of the dopamine D2 receptor gene is associated with schizophrenia in a Spanish population.
    Psychiatric genetics, 2008, Volume: 18, Issue:3

    Topics: Age Distribution; Alleles; Case-Control Studies; Cytosine; Female; Gene Frequency; Genetic Predispos

2008
C to T nucleotide substitution in codon 713 of amyloid precursor protein gene not found in 86 unrelated schizophrenics from multiplex families.
    American journal of medical genetics, 1993, May-01, Volume: 48, Issue:1

    Topics: Amyloid beta-Protein Precursor; Base Sequence; Chronic Disease; Codon; Cytosine; DNA; Genetic Linkag

1993
Lack of expansion of cytosine adenine guanine trinucleotide repeat in the dentatorubral and pallidoluysian atrophy gene in Swedish schizophrenic patients.
    Biological psychiatry, 1996, Aug-01, Volume: 40, Issue:3

    Topics: Adenine; Alleles; Atrophy; Autoradiography; Chromosomes, Human, Pair 13; Cytosine; Dentate Gyrus; Gl

1996
A family based association study of T102C polymorphism in 5HT2A and schizophrenia plus identification of new polymorphisms in the promoter.
    Molecular psychiatry, 1998, Volume: 3, Issue:1

    Topics: Adult; Base Sequence; Cytosine; DNA Primers; Female; Homozygote; Humans; Male; Nuclear Family; Point

1998
C677T polymorphism in methylenetetrahydrofolate reductase gene and psychoses.
    Molecular psychiatry, 1998, Volume: 3, Issue:5

    Topics: Adult; Age Factors; Aged; Alleles; Bipolar Disorder; Cytosine; Depressive Disorder; Gene Frequency;

1998
Association between the methylenetetrahydrofolate reductase 677C-->T missense mutation and schizophrenia.
    Molecular psychiatry, 2000, Volume: 5, Issue:3

    Topics: Adult; Alleles; Antipsychotic Agents; Cytosine; Female; Genotype; Humans; Male; Methylenetetrahydrof

2000
Association study of CAG repeats in the KCNN3 gene in Japanese patients with schizophrenia, schizoaffective disorder and bipolar disorder.
    Psychiatry research, 2001, Apr-15, Volume: 101, Issue:3

    Topics: Adenine; Adult; Alleles; Asian People; Bipolar Disorder; Case-Control Studies; Cytosine; Female; Gua

2001
Lack of impact of CYP1A2 genetic polymorphism (C/A polymorphism at position 734 in intron 1 and G/A polymorphism at position -2964 in the 5'-flanking region of CYP1A2) on the plasma concentration of haloperidol in smoking male Japanese with schizophrenia.
    Progress in neuro-psychopharmacology & biological psychiatry, 2002, Volume: 26, Issue:2

    Topics: 5' Flanking Region; Adenine; Adult; Aged; Antipsychotic Agents; Cytochrome P-450 CYP1A2; Cytosine; E

2002
Cryptococcal meningitis: its apparent increased incidence in the Far East.
    Brain : a journal of neurology, 1972, Volume: 95, Issue:4

    Topics: Adolescent; Adult; Amphotericin B; Animals; Asian People; Cerebrospinal Fluid Proteins; Child; Colum

1972