cytosine has been researched along with Crohn Disease in 3 studies
Crohn Disease: A chronic transmural inflammation that may involve any part of the DIGESTIVE TRACT from MOUTH to ANUS, mostly found in the ILEUM, the CECUM, and the COLON. In Crohn disease, the inflammation, extending through the intestinal wall from the MUCOSA to the serosa, is characteristically asymmetric and segmental. Epithelioid GRANULOMAS may be seen in some patients.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Delayed growth is common in pediatric Crohn's disease (CD)." | 1.33 | TNF promoter polymorphisms and modulation of growth retardation and disease severity in pediatric Crohn's disease. ( Friedlander, M; Kaniel, Y; Karban, A; Leshinsky-Silver, E; Levine, A; Reif, SS; Shamir, R; Shaoul, RR; Weiss, B; Wine, E; Yakir, B, 2005) |
| "Crohn's disease is a chronic inflammatory disorder of the gastrointestinal tract, which is thought to result from the effect of environmental factors in a genetically predisposed host." | 1.31 | A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease. ( Achkar, JP; Bayless, TM; Bonen, DK; Brant, SR; Britton, H; Chen, FF; Cho, JH; Duerr, RH; Hanauer, SB; Inohara, N; Karaliuskas, R; Kirschner, BS; Moran, T; Nicolae, DL; Nuñez, G; Ogura, Y; Ramos, R, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Linde, Kv | 1 |
| Boor, PP | 1 |
| Houwing-Duistermaat, JJ | 1 |
| Kuipers, EJ | 1 |
| Wilson, JH | 1 |
| de Rooij, FW | 1 |
| Levine, A | 1 |
| Shamir, R | 1 |
| Wine, E | 1 |
| Weiss, B | 1 |
| Karban, A | 1 |
| Shaoul, RR | 1 |
| Reif, SS | 1 |
| Yakir, B | 1 |
| Friedlander, M | 1 |
| Kaniel, Y | 1 |
| Leshinsky-Silver, E | 1 |
| Ogura, Y | 1 |
| Bonen, DK | 1 |
| Inohara, N | 1 |
| Nicolae, DL | 1 |
| Chen, FF | 1 |
| Ramos, R | 1 |
| Britton, H | 1 |
| Moran, T | 1 |
| Karaliuskas, R | 1 |
| Duerr, RH | 1 |
| Achkar, JP | 1 |
| Brant, SR | 1 |
| Bayless, TM | 1 |
| Kirschner, BS | 1 |
| Hanauer, SB | 1 |
| Nuñez, G | 1 |
| Cho, JH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Double-blind, Randomized, Placebo-controlled Multicenter Study to Assess the Safety and Efficacy of AST-120 in Mild to Moderately Active Crohn's Patients With Fistulas[NCT00321412] | Phase 3 | 191 participants (Actual) | Interventional | 2006-03-31 | Completed | ||
| Genetic Markers as Predictors of Phenotypes in Pediatric Onset Crohn's Disease[NCT00783575] | 0 participants (Actual) | Observational | 2002-10-31 | Withdrawn (stopped due to PI has left institution) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 other studies available for cytosine and Crohn Disease
| Article | Year |
|---|---|
Card15 and Crohn's disease: healthy homozygous carriers of the 3020insC frameshift mutation.
Topics: Adult; Aged; Carrier Proteins; Case-Control Studies; Crohn Disease; Cytosine; Electrophoresis, Agar | 2003 |
TNF promoter polymorphisms and modulation of growth retardation and disease severity in pediatric Crohn's disease.
Topics: Adenine; Adolescent; Child; Cohort Studies; Crohn Disease; Cytosine; Female; Genotype; Growth Disord | 2005 |
A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease.
Topics: Adult; Alleles; Amino Acid Sequence; Base Sequence; Carrier Proteins; Case-Control Studies; Cell Lin | 2001 |
A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease.
Topics: Adult; Alleles; Amino Acid Sequence; Base Sequence; Carrier Proteins; Case-Control Studies; Cell Lin | 2001 |
A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease.
Topics: Adult; Alleles; Amino Acid Sequence; Base Sequence; Carrier Proteins; Case-Control Studies; Cell Lin | 2001 |
A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease.
Topics: Adult; Alleles; Amino Acid Sequence; Base Sequence; Carrier Proteins; Case-Control Studies; Cell Lin | 2001 |