cytosine has been researched along with Cell Transformation, Neoplastic in 58 studies
Cell Transformation, Neoplastic: Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We have recently shown in in vitro studies that inflammation-mediated halogenated cytosine damage products can mimic 5-methylcytosine in directing enzymatic DNA methylation and in enhancing the binding of methyl-binding proteins whereas certain oxidative damage products inhibit both." | 8.84 | Inflammation-mediated cytosine damage: a mechanistic link between inflammation and the epigenetic alterations in human cancers. ( Sowers, LC; Valinluck, V, 2007) |
| " Epigenetic diversity is linked to unfavorable clinical outcomes, clonal selection at relapse, and is driven at least in part because of the actions of activation-induced cytosine deaminase, which is a unique feature of B-cell lymphomas." | 4.93 | The many layers of epigenetic dysfunction in B-cell lymphomas. ( Dominguez, PM; Jiang, Y; Melnick, AM, 2016) |
| " We have recently shown in in vitro studies that inflammation-mediated halogenated cytosine damage products can mimic 5-methylcytosine in directing enzymatic DNA methylation and in enhancing the binding of methyl-binding proteins whereas certain oxidative damage products inhibit both." | 4.84 | Inflammation-mediated cytosine damage: a mechanistic link between inflammation and the epigenetic alterations in human cancers. ( Sowers, LC; Valinluck, V, 2007) |
| " The precise functional role of 5-hydroxymethylcytosine in breast cancer remains elusive." | 4.12 | Locus-Specific Enrichment Analysis of 5-Hydroxymethylcytosine Reveals Novel Genes Associated with Breast Carcinogenesis. ( Balaiah, M; Mani, S; Ramasamy, D; Rao, AKDM; Sundersingh, S; Thangarajan, R; Veluswami, S; Vittal Rangan, A, 2022) |
| "More than 50% of colon cancer-associated mutations in the p53 tumor suppressor gene are C-->T transitions." | 2.41 | Thymine DNA glycosylase. ( Bentele, M; Hardeland, U; Jiricny, J; Lettieri, T; Schär, P; Steinacher, R, 2001) |
| "The mutations found in murine tumors are similar to those found in human skin cancers, and PMA promotes proliferation of human skin cells." | 1.51 | A Tumor-Promoting Phorbol Ester Causes a Large Increase in APOBEC3A Expression and a Moderate Increase in APOBEC3B Expression in a Normal Human Keratinocyte Cell Line without Increasing Genomic Uracils. ( Bhagwat, AS; Perera, MLW; Senevirathne, V; Siriwardena, SU; Stewart, J, 2019) |
| "Analysis of pancreatic cancer samples revealed striking redistribution of 5-hmC sites in cancer cells and demonstrated enrichment of this modification at many oncogenic promoters such as GATA6." | 1.39 | Genome-wide hydroxymethylation tested using the HELP-GT assay shows redistribution in cancer. ( Bhagat, TD; Bhattacharyya, S; Campbell, N; Christopeit, M; Godley, L; Greally, JM; Maitra, A; Mazdo, J; Nischal, S; Parekh, S; Steidl, U; Suzuki, M; Vasanthakumar, A; Verma, A; Yu, Y, 2013) |
| "Cadmium is a human carcinogen that likely acts via epigenetic mechanisms." | 1.32 | Effects of cadmium on DNA-(Cytosine-5) methyltransferase activity and DNA methylation status during cadmium-induced cellular transformation. ( Achanzar, WE; Li, G; Qu, W; Takiguchi, M; Waalkes, MP, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 23 (39.66) | 18.7374 |
| 1990's | 10 (17.24) | 18.2507 |
| 2000's | 6 (10.34) | 29.6817 |
| 2010's | 16 (27.59) | 24.3611 |
| 2020's | 3 (5.17) | 2.80 |
| Authors | Studies |
|---|---|
| Aivalioti, MM | 1 |
| Bartholdy, BA | 1 |
| Pradhan, K | 1 |
| Bhagat, TD | 2 |
| Zintiridou, A | 1 |
| Jeong, JJ | 1 |
| Thiruthuvanathan, VJ | 1 |
| Pujato, M | 1 |
| Paranjpe, A | 1 |
| Zhang, C | 1 |
| Levine, RL | 1 |
| Viny, AD | 1 |
| Wickrema, A | 1 |
| Verma, A | 2 |
| Will, B | 1 |
| Ramasamy, D | 1 |
| Rao, AKDM | 1 |
| Balaiah, M | 1 |
| Vittal Rangan, A | 1 |
| Sundersingh, S | 1 |
| Veluswami, S | 1 |
| Thangarajan, R | 1 |
| Mani, S | 1 |
| An, J | 2 |
| Ko, M | 2 |
| Pistore, C | 1 |
| Giannoni, E | 1 |
| Colangelo, T | 1 |
| Rizzo, F | 1 |
| Magnani, E | 1 |
| Muccillo, L | 1 |
| Giurato, G | 1 |
| Mancini, M | 1 |
| Rizzo, S | 1 |
| Riccardi, M | 1 |
| Sahnane, N | 1 |
| Del Vescovo, V | 1 |
| Kishore, K | 1 |
| Mandruzzato, M | 1 |
| Macchi, F | 1 |
| Pelizzola, M | 1 |
| Denti, MA | 1 |
| Furlan, D | 1 |
| Weisz, A | 1 |
| Colantuoni, V | 1 |
| Chiarugi, P | 1 |
| Bonapace, IM | 1 |
| Siriwardena, SU | 1 |
| Perera, MLW | 1 |
| Senevirathne, V | 1 |
| Stewart, J | 1 |
| Bhagwat, AS | 1 |
| Zhang, LT | 1 |
| Zhang, LJ | 1 |
| Zhang, JJ | 1 |
| Ye, XX | 1 |
| Xie, AM | 1 |
| Chen, LY | 1 |
| Kang, JX | 1 |
| Cai, C | 1 |
| Thomson, JP | 1 |
| Hunter, JM | 1 |
| Lempiäinen, H | 1 |
| Müller, A | 1 |
| Terranova, R | 1 |
| Moggs, JG | 1 |
| Meehan, RR | 1 |
| Sakata-Yanagimoto, M | 1 |
| Chiba, S | 1 |
| Mason, EF | 1 |
| Hornick, JL | 1 |
| Bhattacharyya, S | 1 |
| Yu, Y | 1 |
| Suzuki, M | 1 |
| Campbell, N | 1 |
| Mazdo, J | 1 |
| Vasanthakumar, A | 1 |
| Nischal, S | 1 |
| Christopeit, M | 1 |
| Parekh, S | 1 |
| Steidl, U | 1 |
| Godley, L | 1 |
| Maitra, A | 1 |
| Greally, JM | 1 |
| Wu, YC | 1 |
| Ling, ZQ | 2 |
| Tessema, M | 1 |
| Yingling, CM | 1 |
| Snider, AM | 1 |
| Do, K | 1 |
| Juri, DE | 1 |
| Picchi, MA | 1 |
| Zhang, X | 1 |
| Liu, Y | 2 |
| Leng, S | 1 |
| Tellez, CS | 1 |
| Belinsky, SA | 1 |
| Karatayli-Ozgursoy, S | 1 |
| Bishop, JA | 1 |
| Hillel, A | 1 |
| Akst, L | 1 |
| Best, SR | 1 |
| Han, JA | 1 |
| Jiang, Y | 1 |
| Dominguez, PM | 1 |
| Melnick, AM | 1 |
| Blanco, S | 1 |
| Bandiera, R | 1 |
| Popis, M | 1 |
| Hussain, S | 1 |
| Lombard, P | 1 |
| Aleksic, J | 1 |
| Sajini, A | 1 |
| Tanna, H | 1 |
| Cortés-Garrido, R | 1 |
| Gkatza, N | 1 |
| Dietmann, S | 1 |
| Frye, M | 1 |
| Kudo, Y | 1 |
| Tateishi, K | 1 |
| Yamamoto, K | 1 |
| Yamamoto, S | 1 |
| Asaoka, Y | 1 |
| Ijichi, H | 1 |
| Nagae, G | 1 |
| Yoshida, H | 1 |
| Aburatani, H | 1 |
| Koike, K | 1 |
| Yang, H | 1 |
| Bai, F | 1 |
| Zhang, JY | 1 |
| Ma, SH | 1 |
| Liu, J | 1 |
| Xu, ZD | 1 |
| Zhu, HG | 1 |
| Ye, D | 1 |
| Guan, KL | 1 |
| Xiong, Y | 1 |
| Stephens, PJ | 1 |
| Tarpey, PS | 1 |
| Davies, H | 1 |
| Van Loo, P | 1 |
| Greenman, C | 1 |
| Wedge, DC | 1 |
| Nik-Zainal, S | 1 |
| Martin, S | 1 |
| Varela, I | 1 |
| Bignell, GR | 1 |
| Yates, LR | 1 |
| Papaemmanuil, E | 1 |
| Beare, D | 1 |
| Butler, A | 1 |
| Cheverton, A | 1 |
| Gamble, J | 1 |
| Hinton, J | 1 |
| Jia, M | 1 |
| Jayakumar, A | 1 |
| Jones, D | 1 |
| Latimer, C | 1 |
| Lau, KW | 1 |
| McLaren, S | 1 |
| McBride, DJ | 1 |
| Menzies, A | 1 |
| Mudie, L | 1 |
| Raine, K | 1 |
| Rad, R | 1 |
| Chapman, MS | 1 |
| Teague, J | 1 |
| Easton, D | 1 |
| Langerød, A | 1 |
| Lee, MT | 1 |
| Shen, CY | 1 |
| Tee, BT | 1 |
| Huimin, BW | 1 |
| Broeks, A | 1 |
| Vargas, AC | 1 |
| Turashvili, G | 1 |
| Martens, J | 1 |
| Fatima, A | 1 |
| Miron, P | 1 |
| Chin, SF | 1 |
| Thomas, G | 1 |
| Boyault, S | 1 |
| Mariani, O | 1 |
| Lakhani, SR | 1 |
| van de Vijver, M | 1 |
| van 't Veer, L | 1 |
| Foekens, J | 1 |
| Desmedt, C | 1 |
| Sotiriou, C | 1 |
| Tutt, A | 1 |
| Caldas, C | 1 |
| Reis-Filho, JS | 1 |
| Aparicio, SA | 1 |
| Salomon, AV | 1 |
| Børresen-Dale, AL | 1 |
| Richardson, AL | 1 |
| Campbell, PJ | 1 |
| Futreal, PA | 1 |
| Stratton, MR | 1 |
| Bestor, TH | 2 |
| Takiguchi, M | 1 |
| Achanzar, WE | 1 |
| Qu, W | 1 |
| Li, G | 1 |
| Waalkes, MP | 1 |
| Valinluck, V | 1 |
| Sowers, LC | 1 |
| Riggs, AD | 1 |
| Jones, PA | 4 |
| Frost, P | 1 |
| Liteplo, RG | 1 |
| Donaghue, TP | 1 |
| Kerbel, RS | 1 |
| Searle, S | 1 |
| Gillespie, DA | 1 |
| Chiswell, DJ | 1 |
| Wyke, JA | 1 |
| Doerfler, W | 2 |
| Diala, ES | 1 |
| Hoffman, RM | 1 |
| Vardimon, L | 1 |
| Renz, D | 1 |
| Groffen, J | 1 |
| Heisterkamp, N | 1 |
| Blennerhassett, G | 1 |
| Stephenson, JR | 1 |
| Nyce, J | 1 |
| Weinhouse, S | 1 |
| Magee, PN | 1 |
| Boehm, TL | 1 |
| Drahovsky, D | 1 |
| Little, M | 1 |
| Wainwright, B | 1 |
| Rideout, WM | 2 |
| Eversole-Cire, P | 1 |
| Spruck, CH | 2 |
| Hustad, CM | 1 |
| Coetzee, GA | 1 |
| Gonzales, FA | 1 |
| Vertino, PM | 1 |
| Spillare, EA | 1 |
| Harris, CC | 1 |
| Baylin, SB | 2 |
| Wu, J | 1 |
| Herman, JG | 1 |
| Wilson, G | 1 |
| Lee, RY | 1 |
| Yen, RW | 1 |
| Mabry, M | 1 |
| de Bustros, A | 1 |
| Nelkin, BD | 1 |
| Schmutte, C | 1 |
| Yang, AS | 1 |
| Nguyen, TT | 1 |
| Beart, RW | 1 |
| Heby, O | 1 |
| Bakin, AV | 1 |
| Curran, T | 1 |
| Qu, G | 1 |
| Dubeau, L | 1 |
| Narayan, A | 1 |
| Yu, MC | 1 |
| Ehrlich, M | 1 |
| Huang, Y | 1 |
| He, T | 1 |
| Domann, FE | 1 |
| Warnecke, PM | 1 |
| Tsukuda, K | 1 |
| Tanino, M | 1 |
| Soga, H | 1 |
| Shimizu, N | 1 |
| Shimizu, K | 1 |
| Hardeland, U | 1 |
| Bentele, M | 1 |
| Lettieri, T | 1 |
| Steinacher, R | 1 |
| Jiricny, J | 1 |
| Schär, P | 1 |
| Browne, MJ | 1 |
| Burdon, RH | 1 |
| Burtseva, NN | 1 |
| Demidkina, NP | 1 |
| Azizov, IuM | 1 |
| Vaniushin, BF | 1 |
| Patt, LM | 1 |
| Van Nest, GA | 1 |
| Grimes, WJ | 1 |
| Ohe, K | 1 |
| Oppenheim, LB | 1 |
| Shen, JC | 1 |
| Tsai, YC | 1 |
| Durante, M | 1 |
| Cecchini, E | 1 |
| Natali, L | 1 |
| Citti, L | 1 |
| Geri, C | 1 |
| Parenti, R | 1 |
| Nuti Ronchi, V | 1 |
| Gama-Sosa, MA | 1 |
| Breznik, T | 1 |
| Butel, JS | 1 |
| Medina, D | 1 |
| Cohen, JC | 1 |
| Khodosova, IA | 1 |
| Hopkins, RC | 1 |
| Goldstein, S | 1 |
| Shmookler Reis, RJ | 1 |
| Kára, J | 1 |
| Rubery, ED | 1 |
| Newton, AA | 1 |
| Nass, MM | 1 |
| Guillé, E | 1 |
| Quetier, F | 1 |
| Calvin, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Investigation of the Prognostic Value of Genomic Alterations or Protein Expression in Patients With Operated Early Breast Cancer of Luminal A or Luminal B Subtypes[NCT04403984] | 750 participants (Actual) | Observational | 2013-04-24 | Active, not recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
15 reviews available for cytosine and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
Epigenetic Modification of Cytosines in Hematopoietic Differentiation and Malignant Transformation.
Topics: 5-Methylcytosine; Animals; Cell Differentiation; Cell Transformation, Neoplastic; Cytosine; Dioxygen | 2023 |
Aberrant cytosine hydroxymethylation in hematologic malignancies.
Topics: Animals; Cell Transformation, Neoplastic; Cytosine; Dioxygenases; DNA Methylation; DNA-Binding Prote | 2013 |
The role of TET family proteins and 5-hydroxymethylcytosine in human tumors.
Topics: 5-Methylcytosine; Cell Transformation, Neoplastic; Cytosine; DNA Methylation; DNA-Binding Proteins; | 2014 |
Functions of TET Proteins in Hematopoietic Transformation.
Topics: 5-Methylcytosine; Animals; Cell Transformation, Neoplastic; Cytosine; Dioxygenases; DNA (Cytosine-5- | 2015 |
The many layers of epigenetic dysfunction in B-cell lymphomas.
Topics: Cell Transformation, Neoplastic; Chromatin; Clonal Evolution; Cytosine; Dioxygenases; DNA Methylatio | 2016 |
Unanswered questions about the role of promoter methylation in carcinogenesis.
Topics: Cell Transformation, Neoplastic; Cytosine; DNA Methylation; Humans; Promoter Regions, Genetic | 2003 |
Inflammation-mediated cytosine damage: a mechanistic link between inflammation and the epigenetic alterations in human cancers.
Topics: Animals; Cell Transformation, Neoplastic; Cytosine; DNA Damage; DNA Methylation; Epigenesis, Genetic | 2007 |
5-methylcytosine, gene regulation, and cancer.
Topics: 5-Methylcytosine; Animals; Azacitidine; Base Sequence; Carcinogens; Cell Transformation, Neoplastic; | 1983 |
DNA methylation--a regulatory signal in eukaryotic gene expression.
Topics: 5-Methylcytosine; Adenoviridae; Animals; Bacteriophages; Base Sequence; Cell Transformation, Neoplas | 1981 |
5-Methylcytosine depletion during tumour development: an extension of the miscoding concept.
Topics: 5-Methylcytosine; Alkylation; Amino Acid Metabolism, Inborn Errors; Animals; Carcinogens; Cell Trans | 1983 |
DNA methylation and polyamines in embryonic development and cancer.
Topics: 5-Methylcytosine; Animals; Cell Transformation, Neoplastic; Cytosine; DNA; DNA (Cytosine-5-)-Methylt | 1995 |
Cytosine methylation and human cancer.
Topics: Cell Transformation, Neoplastic; Cytosine; DNA Methylation; Humans; Neoplasms | 2000 |
Thymine DNA glycosylase.
Topics: Amino Acid Sequence; Animals; Bacterial Proteins; Base Pair Mismatch; Base Sequence; Cell Transforma | 2001 |
Methylation, mutation and cancer.
Topics: 5-Methylcytosine; Animals; Cell Transformation, Neoplastic; Cytosine; Deamination; DNA; DNA, Neoplas | 1992 |
[Role of enzymatic DNA methylation in cell differentiation and carcinogenesis].
Topics: Animals; Base Composition; Carcinogens; Cell Differentiation; Cell Transformation, Neoplastic; Cytos | 1985 |
43 other studies available for cytosine and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
PU.1-Dependent Enhancer Inhibition Separates Tet2-Deficient Hematopoiesis from Malignant Transformation.
Topics: Animals; Cell Transformation, Neoplastic; Cytosine; Dioxygenases; DNA-Binding Proteins; Enhancer Ele | 2022 |
Locus-Specific Enrichment Analysis of 5-Hydroxymethylcytosine Reveals Novel Genes Associated with Breast Carcinogenesis.
Topics: 5-Methylcytosine; Breast Neoplasms; Cell Transformation, Neoplastic; Cytosine; DNA, Intergenic; Fema | 2022 |
DNA methylation variations are required for epithelial-to-mesenchymal transition induced by cancer-associated fibroblasts in prostate cancer cells.
Topics: Cancer-Associated Fibroblasts; Cell Line, Tumor; Cell Transformation, Neoplastic; Culture Media, Con | 2017 |
A Tumor-Promoting Phorbol Ester Causes a Large Increase in APOBEC3A Expression and a Moderate Increase in APOBEC3B Expression in a Normal Human Keratinocyte Cell Line without Increasing Genomic Uracils.
Topics: Carcinogens; Cell Line; Cell Transformation, Neoplastic; Cytidine Deaminase; Cytosine; DNA, Single-S | 2019 |
Quantification of the sixth DNA base 5-hydroxymethylcytosine in colorectal cancer tissue and C-26 cell line.
Topics: 5-Methylcytosine; Cell Line, Tumor; Cell Transformation, Neoplastic; Chromatography, Liquid; Colorec | 2013 |
Dynamic changes in 5-hydroxymethylation signatures underpin early and late events in drug exposed liver.
Topics: 5-Methylcytosine; Animals; Carcinogens; Cell Transformation, Neoplastic; Cytochrome P-450 Enzyme Sys | 2013 |
Succinate dehydrogenase deficiency is associated with decreased 5-hydroxymethylcytosine production in gastrointestinal stromal tumors: implications for mechanisms of tumorigenesis.
Topics: 5-Methylcytosine; Biomarkers, Tumor; Cell Transformation, Neoplastic; Cytosine; DNA Mutational Analy | 2013 |
Genome-wide hydroxymethylation tested using the HELP-GT assay shows redistribution in cancer.
Topics: 5-Methylcytosine; Animals; Cell Line, Tumor; Cell Transformation, Neoplastic; Cytosine; DNA, Neoplas | 2013 |
GATA2 is epigenetically repressed in human and mouse lung tumors and is not requisite for survival of KRAS mutant lung cancer.
Topics: Animals; Carcinoma, Non-Small-Cell Lung; Cell Death; Cell Line, Tumor; Cell Survival; Cell Transform | 2014 |
Risk Factors for Dysplasia in Recurrent Respiratory Papillomatosis in an Adult and Pediatric Population.
Topics: Adolescent; Adult; Age of Onset; Aged; Aged, 80 and over; Antiviral Agents; Carcinoma; Cell Transfor | 2016 |
Stem cell function and stress response are controlled by protein synthesis.
Topics: Animals; Cell Differentiation; Cell Proliferation; Cell Transformation, Neoplastic; Cytosine; Female | 2016 |
Loss of 5-hydroxymethylcytosine is accompanied with malignant cellular transformation.
Topics: 5-Methylcytosine; Cell Line, Tumor; Cell Transformation, Neoplastic; Colorectal Neoplasms; Cytosine; | 2012 |
Tumor development is associated with decrease of TET gene expression and 5-methylcytosine hydroxylation.
Topics: 5-Methylcytosine; Animals; Biomarkers, Tumor; Cell Transformation, Neoplastic; Cytosine; Dioxygenase | 2013 |
The landscape of cancer genes and mutational processes in breast cancer.
Topics: Age Factors; Breast Neoplasms; Cell Transformation, Neoplastic; Cytosine; DNA Mutational Analysis; F | 2012 |
Effects of cadmium on DNA-(Cytosine-5) methyltransferase activity and DNA methylation status during cadmium-induced cellular transformation.
Topics: Animals; Binding Sites; Cadmium; Carcinogens; Cell Division; Cell Line; Cell Transformation, Neoplas | 2003 |
Selection of strongly immunogenic "tum-" variants from tumors at high frequency using 5-azacytidine.
Topics: 5-Methylcytosine; Animals; Antigens, Neoplasm; Azacitidine; Cell Transformation, Neoplastic; Cytosin | 1984 |
Analysis of the variations in proviral cytosine methylation that accompany transformation and morphological reversion in a line of Rous sarcoma virus-infected Rat-1 cells.
Topics: 5-Methylcytosine; Animals; Avian Sarcoma Viruses; Azacitidine; Base Sequence; Cell Line; Cell Transf | 1984 |
DNA methylation levels in normal and chemically-transformed mouse 3T3 cells.
Topics: 5-Methylcytosine; Animals; Base Composition; Benzo(a)pyrene; Benzopyrenes; Cell Line; Cell Transform | 1982 |
Can DNA methylation regulate gene expression?
Topics: 5-Methylcytosine; Adenoviruses, Human; Animals; Cell Line; Cell Transformation, Neoplastic; Cytosine | 1983 |
Regulation of viral and cellular oncogene expression by cytosine methylation.
Topics: Animals; Base Sequence; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Clon | 1983 |
Alteration of enzymatic methylation of DNA cytosines by chemical carcinogens: a mechanism involved in the initiation of carcinogenesis.
Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Cytosine; DNA; DNA (Cytosine | 1983 |
Methylation and p16: suppressing the suppressor.
Topics: 5-Methylcytosine; Carrier Proteins; Cell Transformation, Neoplastic; Cocarcinogenesis; CpG Islands; | 1995 |
Progressive increases in the methylation status and heterochromatinization of the myoD CpG island during oncogenic transformation.
Topics: 5-Methylcytosine; Animals; Base Sequence; Cell Cycle; Cell Line; Cell Transformation, Neoplastic; Cy | 1994 |
Altered chromosomal methylation patterns accompany oncogene-induced transformation of human bronchial epithelial cells.
Topics: Base Sequence; Bronchi; Calcitonin; Cell Transformation, Neoplastic; Chromosomes, Human, Pair 11; Ch | 1993 |
Expression of prokaryotic HhaI DNA methyltransferase is transforming and lethal to NIH 3T3 cells.
Topics: 3T3 Cells; Animals; Base Sequence; Cell Death; Cell Survival; Cell Transformation, Neoplastic; Cytos | 1996 |
Mechanisms for the involvement of DNA methylation in colon carcinogenesis.
Topics: Base Sequence; Cell Transformation, Neoplastic; Colonic Neoplasms; Cytosine; DNA; DNA (Cytosine-5-)- | 1996 |
Role of DNA 5-methylcytosine transferase in cell transformation by fos.
Topics: 5-Methylcytosine; Acetylation; Animals; Cell Size; Cell Transformation, Neoplastic; Cytosine; DNA (C | 1999 |
Satellite DNA hypomethylation vs. overall genomic hypomethylation in ovarian epithelial tumors of different malignant potential.
Topics: 5-Methylcytosine; Carcinoma; Cell Transformation, Neoplastic; Centromere; Chromosomes, Human, Pair 1 | 1999 |
Decreased expression of manganese superoxide dismutase in transformed cells is associated with increased cytosine methylation of the SOD2 gene.
Topics: Alu Elements; Cell Line, Transformed; Cell Transformation, Neoplastic; CpG Islands; Cytosine; DNA Me | 1999 |
A novel activating mutation of the K-ras gene in human primary colon adenocarcinoma.
Topics: 3T3 Cells; Adenine; Adenocarcinoma; Animals; Base Sequence; Cell Transformation, Neoplastic; Colonic | 2000 |
The sequence specificity of vertebrate DNA methylation.
Topics: Animals; Base Sequence; Biological Evolution; Cell Fractionation; Cell Line; Cell Transformation, Ne | 1977 |
[Changes in the specificity of DNA methylation in cattle blood lymphocytes under chronic lymphoid leukemia].
Topics: Animals; Cattle; Cattle Diseases; Cell Transformation, Neoplastic; Cytosine; DNA; DNA (Cytosine-5-)- | 1978 |
A comparison of glycosyltransferase activities and malignant properties in normal and transformed cells derived from BALB/c mice.
Topics: Agglutination; Animals; Cell Transformation, Neoplastic; Cells, Cultured; Concanavalin A; Cytosine; | 1975 |
Low frequency of (5'-3') -C-G- connection in 70S RNA from simian sarcoma virus.
Topics: Animals; Base Sequence; Cell Line; Cell Transformation, Neoplastic; Cytosine; Guanine; Oligonucleoti | 1975 |
5-azacytidine-induced tumorous transformation and DNA hypomethylation in Nicotiana tissue cultures.
Topics: 5-Methylcytosine; Azacitidine; Cell Transformation, Neoplastic; Cells, Cultured; Cytosine; Deoxyribo | 1989 |
Mammary preneoplasia and tumorigenesis in the BALB/c mouse: structure and modification of mouse mammary tumor virus DNA sequences.
Topics: 5-Methylcytosine; 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Cytosi | 1987 |
A molecular model relating to carcinogenesis.
Topics: Cell Transformation, Neoplastic; Cisplatin; Cytosine; DNA; DNA, Neoplasm; Methylation; Models, Molec | 1985 |
Methylation patterns in the gene for the alpha subunit of chorionic gonadotropin are inherited with variable fidelity in clonal lineages of human fibroblasts.
Topics: 5-Methylcytosine; Cell Transformation, Neoplastic; Cells, Cultured; Chorionic Gonadotropin; Cytosine | 1985 |
Induction of deoxycytidylate deaminase and uridine kinase and activation of cellular DNA synthesis in the course of transformation of chicken embryo cells infected by Rous sarcoma virus in vitro.
Topics: Amidohydrolases; Animals; Avian Sarcoma Viruses; Carbon Isotopes; Cell Transformation, Neoplastic; C | 1968 |
DNA methylation in normal and tumour virus-transformed cells in tissue culture. I. The level of DNA methylation in BHK21 cells and in BHK21 cells transformed by polyoma virus (PyY cells).
Topics: Animals; Carbon Radioisotopes; Cell Line; Cell Transformation, Neoplastic; Chromatography, Paper; Cl | 1973 |
Differential methylation of mitochondrial and nuclear DNA in cultured mouse, hamster and virus-transformed hamster cells. In vivo and in vitro methylation.
Topics: Animals; Avian Sarcoma Viruses; Cell Line; Cell Transformation, Neoplastic; Centrifugation, Density | 1973 |
[The "crown-gall": experimental model for the study of mechanism of tumoral transformation].
Topics: Cell Transformation, Neoplastic; Cytosine; DNA, Bacterial; DNA, Neoplasm; Genetic Code; Guanine; Hyb | 1970 |
Carcinogenesis: chemical and otherwise.
Topics: Animals; Benzopyrenes; Binding Sites; Carcinogens; Cell Transformation, Neoplastic; Chemical Phenome | 1972 |