Page last updated: 2024-10-17

cytosine and Carcinoma

cytosine has been researched along with Carcinoma in 28 studies

Carcinoma: A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm and not a synonym for cancer.

Research Excerpts

ExcerptRelevanceReference
" Therefore, the aim of the present study was to assess a possible link between 8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxodG) background level and 5-methylcytosine content in DNA from human leukocytes of healthy subjects (n=105) as well as in patients with colon adenomas (n=39) and carcinomas (n=50)."7.74The relationship between 8-oxo-7,8-dihydro-2'-deoxyguanosine level and extent of cytosine methylation in leukocytes DNA of healthy subjects and in patients with colon adenomas and carcinomas. ( Dziaman, T; Foksinski, M; Gackowski, D; Guz, J; Olinski, R; Rozalski, R; Siomek, A; Szpila, A, 2008)
"To investigate the behaviour of total plasma homocysteine (tHcy) and its most common genetic determinant defect, the methylenetetrahydrofolate reductase C677T (C677TMTHFR) polymorphism in patients with early stage colorectal carcinoma."7.73Total plasma homocysteine and methylenetetrahydrofolate reductase C677T polymorphism in patients with colorectal carcinoma. ( Battistelli, S; Bing, C; Roviello, F; Stefanoni, M; Vittoria, A, 2006)
"The effect of the antiviral agent (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl) cytosine (cidofovir) on the EBV-associated tumor nasopharyngeal carcinoma (NPC) was evaluated in NPC xenografts in athymic mice."7.70The antiviral agent cidofovir [(S)-1-(3-hydroxy-2-phosphonyl-methoxypropyl)cytosine] has pronounced activity against nasopharyngeal carcinoma grown in nude mice. ( De Clercq, E; Neyts, J; Pagano, JS; Raab-Traub, N; Sadler, R, 1998)
" Therefore, the aim of the present study was to assess a possible link between 8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxodG) background level and 5-methylcytosine content in DNA from human leukocytes of healthy subjects (n=105) as well as in patients with colon adenomas (n=39) and carcinomas (n=50)."3.74The relationship between 8-oxo-7,8-dihydro-2'-deoxyguanosine level and extent of cytosine methylation in leukocytes DNA of healthy subjects and in patients with colon adenomas and carcinomas. ( Dziaman, T; Foksinski, M; Gackowski, D; Guz, J; Olinski, R; Rozalski, R; Siomek, A; Szpila, A, 2008)
"To investigate the behaviour of total plasma homocysteine (tHcy) and its most common genetic determinant defect, the methylenetetrahydrofolate reductase C677T (C677TMTHFR) polymorphism in patients with early stage colorectal carcinoma."3.73Total plasma homocysteine and methylenetetrahydrofolate reductase C677T polymorphism in patients with colorectal carcinoma. ( Battistelli, S; Bing, C; Roviello, F; Stefanoni, M; Vittoria, A, 2006)
"The effect of the antiviral agent (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl) cytosine (cidofovir) on the EBV-associated tumor nasopharyngeal carcinoma (NPC) was evaluated in NPC xenografts in athymic mice."3.70The antiviral agent cidofovir [(S)-1-(3-hydroxy-2-phosphonyl-methoxypropyl)cytosine] has pronounced activity against nasopharyngeal carcinoma grown in nude mice. ( De Clercq, E; Neyts, J; Pagano, JS; Raab-Traub, N; Sadler, R, 1998)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19907 (25.00)18.7374
1990's3 (10.71)18.2507
2000's15 (53.57)29.6817
2010's3 (10.71)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nettersheim, D1
Heukamp, LC1
Fronhoffs, F1
Grewe, MJ1
Haas, N1
Waha, A2
Honecker, F1
Kristiansen, G1
Schorle, H1
Karatayli-Ozgursoy, S1
Bishop, JA1
Hillel, A1
Akst, L1
Best, SR1
Dikkers, FG1
Liu, H1
Zhang, L1
Niu, Z1
Zhou, M1
Peng, C1
Li, X1
Deng, T1
Shi, L1
Tan, Y1
Li, G1
De Schutter, T1
Andrei, G1
Topalis, D1
Duraffour, S1
Mitera, T1
Naesens, L1
van den Oord, J1
Matthys, P1
Snoeck, R2
Abdulkarim, B2
Sabri, S2
Zelenika, D1
Deutsch, E2
Frascogna, V1
Klijanienko, J1
Vainchenker, W2
Joab, I1
Bourhis, J2
Wakisaka, N1
Yoshizaki, T1
Raab-Traub, N3
Pagano, JS3
Gekeler, V1
Gimmnich, P1
Hofmann, HP1
Grebe, C1
Römmele, M1
Leja, A1
Baudler, M1
Benimetskaya, L1
Gonser, B1
Pieles, U1
Maier, T1
Wagner, T1
Sanders, K1
Beck, JF1
Hanauer, G1
Stein, CA1
Battistelli, S1
Vittoria, A1
Stefanoni, M1
Bing, C1
Roviello, F1
Lam, W1
Leung, CH1
Bussom, S1
Cheng, YC1
Choi, JH1
Park, SH1
Park, J1
Park, BG1
Cha, SJ1
Kong, KH1
Lee, KH1
Park, AJ1
Guz, J1
Foksinski, M1
Siomek, A1
Gackowski, D1
Rozalski, R1
Dziaman, T1
Szpila, A1
Olinski, R1
Li, AJ1
Scoles, DR1
Armstrong, KU1
Karlan, BY1
Watanabe, SM1
Goodman, MF1
Pechan, R1
Schuler, M1
Slany, M1
Beck, R1
Pfeiffer, E1
Metzler, M1
Neyts, J1
Sadler, R1
De Clercq, E1
Qu, G1
Dubeau, L1
Narayan, A1
Yu, MC1
Ehrlich, M1
Tamura, G1
Yin, J1
Wang, S1
Fleisher, AS1
Zou, T1
Abraham, JM1
Kong, D1
Smolinski, KN1
Wilson, KT1
James, SP1
Silverberg, SG1
Nishizuka, S1
Terashima, M1
Motoyama, T1
Meltzer, SJ1
Günzburg, WH1
Salmons, B1
Murono, S1
Chagraoui, H1
Maggiorella, L1
Thierry, J1
Eschwege, F1
Chouaïb, S1
Potter, CW1
Oxford, JS1
Downie, JC1
Attwood, MM1
Hardy, RD1
Mosmann, TR1
Hudson, JB1
Kieff, ED1
Bachenheimer, SL1
Roizman, B1
Richards, EG1
Doerfler, W2
Hellmann, W1
Kleinschmidt, AK1
Burlingham, BT1
Pettersson, U1
Philipson, L1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Observational Study on the Investigation of the Molecular Mechanism and Clinical Significance of the Interplay Between Twist1 and Other EMT Regulators Through microRNA-29 Family.[NCT01927354]100 participants (Anticipated)Observational2012-12-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for cytosine and Carcinoma

ArticleYear
Papillomavirus and treatment.
    Antiviral research, 2006, Volume: 71, Issue:2-3

    Topics: Antiviral Agents; Carcinoma; Chemotherapy, Adjuvant; Cidofovir; Cytosine; Female; Humans; Organophos

2006
Novel clinical strategies for the treatment of pancreatic carcinoma.
    Trends in molecular medicine, 2001, Volume: 7, Issue:1

    Topics: Adjuvants, Immunologic; Antibodies, Monoclonal; Antineoplastic Agents; Bile; Biotransformation; Canc

2001

Other Studies

26 other studies available for cytosine and Carcinoma

ArticleYear
Analysis of TET expression/activity and 5mC oxidation during normal and malignant germ cell development.
    PloS one, 2013, Volume: 8, Issue:12

    Topics: 5-Methylcytosine; Carcinoma; Cell Line, Tumor; Cytosine; DNA Methylation; DNA-Binding Proteins; Down

2013
Risk Factors for Dysplasia in Recurrent Respiratory Papillomatosis in an Adult and Pediatric Population.
    The Annals of otology, rhinology, and laryngology, 2016, Volume: 125, Issue:3

    Topics: Adolescent; Adult; Age of Onset; Aged; Aged, 80 and over; Antiviral Agents; Carcinoma; Cell Transfor

2016
Intralesional cidofovir does not increase the risk of laryngeal dysplasia or laryngeal carcinoma.
    International journal of pediatric otorhinolaryngology, 2008, Volume: 72, Issue:10

    Topics: Animals; Antineoplastic Agents; Carcinogenicity Tests; Carcinoma; Cidofovir; Cytosine; Humans; Infus

2008
Promoter methylation inhibits BRD7 expression in human nasopharyngeal carcinoma cells.
    BMC cancer, 2008, Sep-08, Volume: 8

    Topics: Base Sequence; Binding Sites; Carcinoma; Cell Line, Tumor; Chromosomal Proteins, Non-Histone; CpG Is

2008
Cidofovir treatment improves the pathology caused by the growth of human papillomavirus-positive cervical carcinoma xenografts in athymic nude mice.
    Cancer letters, 2013, Feb-28, Volume: 329, Issue:2

    Topics: Animals; Antineoplastic Agents; Brain; Cachexia; Carcinoma; Cell Line, Tumor; Cidofovir; Cytokines;

2013
Antiviral agent cidofovir decreases Epstein-Barr virus (EBV) oncoproteins and enhances the radiosensitivity in EBV-related malignancies.
    Oncogene, 2003, Apr-17, Volume: 22, Issue:15

    Topics: Animals; Antiviral Agents; Apoptosis; bcl-2-Associated X Protein; Burkitt Lymphoma; Carcinoma; Caspa

2003
Ribonucleotide reductase inhibitors enhance cidofovir-induced apoptosis in EBV-positive nasopharyngeal carcinoma xenografts.
    International journal of cancer, 2005, Sep-10, Volume: 116, Issue:4

    Topics: Animals; Antineoplastic Agents; Apoptosis; Carcinoma; Cidofovir; Cytosine; Drug Interactions; Enzyme

2005
G3139 and other CpG-containing immunostimulatory phosphorothioate oligodeoxynucleotides are potent suppressors of the growth of human tumor xenografts in nude mice.
    Oligonucleotides, 2006,Spring, Volume: 16, Issue:1

    Topics: Adenocarcinoma; Adjuvants, Immunologic; Animals; Antineoplastic Agents; B-Lymphocytes; Carcinoma; Ce

2006
Total plasma homocysteine and methylenetetrahydrofolate reductase C677T polymorphism in patients with colorectal carcinoma.
    World journal of gastroenterology, 2006, Oct-14, Volume: 12, Issue:38

    Topics: Aged; Carcinoma; Cell Proliferation; Colorectal Neoplasms; Cytosine; Female; Genotype; Homocysteine;

2006
The impact of hypoxic treatment on the expression of phosphoglycerate kinase and the cytotoxicity of troxacitabine and gemcitabine.
    Molecular pharmacology, 2007, Volume: 72, Issue:3

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Carcinoma; Carcinoma, Hepatocellular; Cell H

2007
Site-specific methylation of CpG nucleotides in the hTERT promoter region can control the expression of hTERT during malignant progression of colorectal carcinoma.
    Biochemical and biophysical research communications, 2007, Sep-28, Volume: 361, Issue:3

    Topics: Binding Sites; Carcinoma; Colorectal Neoplasms; CpG Islands; Cytosine; DNA Methylation; DNA-Cytosine

2007
The relationship between 8-oxo-7,8-dihydro-2'-deoxyguanosine level and extent of cytosine methylation in leukocytes DNA of healthy subjects and in patients with colon adenomas and carcinomas.
    Mutation research, 2008, Apr-02, Volume: 640, Issue:1-2

    Topics: 5-Methylcytosine; 8-Hydroxy-2'-Deoxyguanosine; Adenoma; Adult; Aged; Aged, 80 and over; Carcinoma; C

2008
Androgen receptor cytosine-adenine-guanine repeat polymorphisms modulate EGFR signaling in epithelial ovarian carcinomas.
    Gynecologic oncology, 2008, Volume: 109, Issue:2

    Topics: Adenine; Alleles; Carcinoma; Cell Line, Tumor; Cell Proliferation; Cytosine; ErbB Receptors; Female;

2008
On the molecular basis of transition mutations: frequencies of forming 2-aminopurine.cytosine and adenine.cytosine base mispairs in vitro.
    Proceedings of the National Academy of Sciences of the United States of America, 1981, Volume: 78, Issue:5

    Topics: 2-Aminopurine; Adenine; Animals; Base Composition; Carcinoma; Cattle; Cell Line; Cytosine; DNA; DNA

1981
Effects of novel 3,4-bisphenylhex(3)enes on cell proliferation in malignant and normal cells.
    Cancer letters, 1996, Jan-02, Volume: 98, Issue:2

    Topics: 5-Methylcytosine; Alkenes; Animals; Antineoplastic Agents; Carcinoma; Cell Division; Cell Line, Tran

1996
The antiviral agent cidofovir [(S)-1-(3-hydroxy-2-phosphonyl-methoxypropyl)cytosine] has pronounced activity against nasopharyngeal carcinoma grown in nude mice.
    Cancer research, 1998, Feb-01, Volume: 58, Issue:3

    Topics: Adolescent; Animals; Antiviral Agents; Apoptosis; Carcinoma; Cidofovir; Cytosine; Drug Screening Ass

1998
Satellite DNA hypomethylation vs. overall genomic hypomethylation in ovarian epithelial tumors of different malignant potential.
    Mutation research, 1999, Jan-25, Volume: 423, Issue:1-2

    Topics: 5-Methylcytosine; Carcinoma; Cell Transformation, Neoplastic; Centromere; Chromosomes, Human, Pair 1

1999
E-Cadherin gene promoter hypermethylation in primary human gastric carcinomas.
    Journal of the National Cancer Institute, 2000, Apr-05, Volume: 92, Issue:7

    Topics: Blotting, Western; Cadherins; Carcinoma; Cytosine; DNA Primers; DNA, Neoplasm; Down-Regulation; Gene

2000
Prevention and inhibition of nasopharyngeal carcinoma growth by antiviral phosphonated nucleoside analogs.
    Cancer research, 2001, Nov-01, Volume: 61, Issue:21

    Topics: Adenine; Animals; Antineoplastic Agents; Apoptosis; Carcinoma; Cell Division; Cidofovir; Cytosine; E

2001
Antiviral agent Cidofovir restores p53 function and enhances the radiosensitivity in HPV-associated cancers.
    Oncogene, 2002, Apr-04, Volume: 21, Issue:15

    Topics: Animals; Antiviral Agents; Carcinoma; Cell Division; Cidofovir; Cyclin A; Cyclin-Dependent Kinase In

2002
Chick embryo lethal orphan (CELO) virus: some physical and immunological properties.
    Virology, 1971, Volume: 44, Issue:2

    Topics: Adenoviridae; Animals; Antigens; Carcinoma; Cell Line; Centrifugation, Density Gradient; Cesium; Chl

1971
Some properties of the genome of murine cytomegalovirus (MCV).
    Virology, 1973, Volume: 54, Issue:1

    Topics: Animals; Carbon Isotopes; Carcinoma; Cell Line; Centrifugation, Density Gradient; Coliphages; Cultur

1973
Size, composition, and structure of the deoxyribonucleic acid of herpes simplex virus subtypes 1 and 2.
    Journal of virology, 1971, Volume: 8, Issue:2

    Topics: Animals; Carbon Isotopes; Carcinoma; Cell Line; Centrifugation, Density Gradient; Cesium; Chlorides;

1971
5S RNA. An analysis of possible base pairing schemes.
    European journal of biochemistry, 1969, Volume: 10, Issue:1

    Topics: Adenine; Carcinoma; Cell Line; Chemical Phenomena; Chemistry; Computers; Cytosine; Escherichia coli;

1969
The DNA of adenovirus type 12 and its denaturation pattern.
    Virology, 1972, Volume: 47, Issue:2

    Topics: Adenoviridae; Alkalies; Carcinoma; Cell Line; Centrifugation, Density Gradient; Cesium; Chlorides; C

1972
Adenovirus endonuclease: association with the penton of adenovirus type 2.
    Journal of molecular biology, 1971, Aug-28, Volume: 60, Issue:1

    Topics: Adenoviridae; Antigens; Carbon Isotopes; Carcinoma; Cell Line; Centrifugation, Zonal; Culture Techni

1971