Page last updated: 2024-10-17

cytosine and Cancer of Stomach

cytosine has been researched along with Cancer of Stomach in 19 studies

Research Excerpts

ExcerptRelevanceReference
"Under study was the nucleotide content and the level of methylated cytosine (5-MC) in the DNA, isolated from adenocarcinoma of the stomach, gastric mucosa in patients with duodenal ulcer as well as from the mucosa of intact human stomach."3.66[Nucleotide composition and the methylated cytosine level in the DNA from a cancerous stomach tumor]. ( Kliasheva, RI; Panfilova, GA; Volkov, VE, 1980)
"Here we show that, in gastric cancers, the 5 hmC decrease correlates with a decrease in ten-eleven translocation 1 (TET1) expression, which is strongly associated with metastasis and poor survival in patients with gastric cancer."1.42Decrease of 5hmC in gastric cancers is associated with TET1 silencing due to with DNA methylation and bivalent histone marks at TET1 CpG island 3'-shore. ( Choi, BY; Kang, GH; Kim, HJ; Kim, M; Kim, SY; Kim, YS; Kwon, OH; Lim, B; Park, JL; Seo, EH; Song, KS, 2015)
"The study population included 177 gastric cancer patients and 224 healthy control subjects."1.33A single nucleotide polymorphism in the MMP-9 promoter affects tumor progression and invasive phenotype of gastric cancer. ( Chayama, K; Imai, K; Kitadai, Y; Matsumura, S; Matsusaki, K; Nakachi, K; Nakayama, H; Oue, N; Yamaguchi, Y; Yasui, W; Yoshida, K, 2005)
"Lymphocyte genomic DNA from 134 Italian gastric cancer patients and 139 controls was used for genotyping two polymorphisms in the TS 5'-untranslated region (5'-UTR); a double (2R) or triple (3R) 28-bp repeat and a G/C polymorphism within the triple repeats allele (3G allele)."1.32Association of thymidylate synthase polymorphisms with gastric cancer susceptibility. ( Bearzi, I; Cascinu, S; Catalano, V; Ficarelli, R; Graziano, F; Humar, B; Kawakami, K; Magnani, M; Merriman, T; Panunzi, S; Ruzzo, A; Santini, D; Testa, E; Tonini, G; Watanabe, G, 2004)
"About 80% of the gastric cancer showed a high level of expression of cyclooxygenase 2, but a subset of cases do not express without unknown reason."1.31Aberrant methylation and histone deacetylation of cyclooxygenase 2 in gastric cancer. ( Fujita, M; Hosokawa, M; Imai, K; Itoh, F; Kikuchi, T; Suzuki, H; Toyota, M; Yamamoto, H, 2002)
"Methylation of hMLH1 promoter from a colorectal cancer cell line RKO and a gastric cancer cell line PACM82 was analyzed by DHPLC."1.31[Analysis of the methylation in CpG island by denaturing high-performance liquid chromatography]. ( Deng, D; Deng, G; Lü, Y, 2001)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19902 (10.53)18.7374
1990's3 (15.79)18.2507
2000's7 (36.84)29.6817
2010's6 (31.58)24.3611
2020's1 (5.26)2.80

Authors

AuthorsStudies
Ahmadi Hedayati, M1
Ahmadi, A1
Khatooni, Z1
Yang, Q1
Wu, K1
Ji, M1
Jin, W1
He, N1
Shi, B1
Hou, P2
Fu, HL1
Ma, Y1
Lu, LG1
Li, BJ1
Jin, WL1
Cui, DX1
Du, C1
Kurabe, N1
Matsushima, Y1
Suzuki, M2
Kahyo, T1
Ohnishi, I1
Tanioka, F1
Tajima, S1
Goto, M1
Yamada, H1
Tao, H1
Shinmura, K1
Konno, H1
Sugimura, H1
Park, JL1
Kim, HJ2
Seo, EH1
Kwon, OH1
Lim, B1
Kim, M1
Kim, SY1
Song, KS1
Kang, GH1
Choi, BY1
Kim, YS1
Chou, NH1
Tsai, CY1
Tu, YT1
Wang, KC1
Kang, CH1
Chang, PM1
Li, GC1
Lam, HC1
Liu, SI1
Tsai, KW1
Yan, L1
Yanan, D1
Donglan, S1
Na, W1
Rongmiao, Z1
Zhifeng, C1
Kudo, Y1
Tateishi, K1
Yamamoto, K1
Yamamoto, S1
Asaoka, Y1
Ijichi, H1
Nagae, G1
Yoshida, H1
Aburatani, H1
Koike, K1
Ashcroft, FJ1
Varro, A1
Dimaline, R1
Dockray, GJ1
Graziano, F1
Kawakami, K1
Watanabe, G1
Ruzzo, A1
Humar, B1
Santini, D1
Catalano, V1
Ficarelli, R1
Merriman, T1
Panunzi, S1
Testa, E1
Cascinu, S1
Bearzi, I1
Tonini, G1
Magnani, M1
Matsumura, S1
Oue, N1
Nakayama, H1
Kitadai, Y1
Yoshida, K1
Yamaguchi, Y1
Imai, K2
Nakachi, K1
Matsusaki, K1
Chayama, K1
Yasui, W1
Akimov, AA1
Lazarev, NV1
Kliasheva, RI1
Volkov, VE1
Panfilova, GA1
Kodama, E1
Shigeta, S1
Suzuki, T1
De Clercq, E1
Hanaoka, K1
Kobayashi, T1
Tanzawa, F1
Tanaka, K1
Shibayama, T1
Miura, S1
Ikeda, T1
Iwabuchi, H1
Nakagawa, A1
Mitsuhashi, Y1
Hisaoka, M1
Kaneko, M1
Tomida, A1
Wataya, Y1
Nomura, T1
Sasaki, T1
Matsuda, A1
Tsuruo, T1
Kurakata, S1
Tamura, G1
Yin, J1
Wang, S1
Fleisher, AS1
Zou, T1
Abraham, JM1
Kong, D1
Smolinski, KN1
Wilson, KT1
James, SP1
Silverberg, SG1
Nishizuka, S1
Terashima, M1
Motoyama, T1
Meltzer, SJ1
Kikuchi, T1
Itoh, F1
Toyota, M1
Suzuki, H1
Yamamoto, H1
Fujita, M1
Hosokawa, M1
Deng, D1
Deng, G1
Lü, Y1
Novikov, LB1
Fedorov, SN1
Iatsuk, OS1
Levanova, GI1
Kalinovskiĭ, VP1
Khanson, KP1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Observational Study on the Investigation of the Molecular Mechanism and Clinical Significance of the Interplay Between Twist1 and Other EMT Regulators Through microRNA-29 Family.[NCT01927354]100 participants (Anticipated)Observational2012-12-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

19 other studies available for cytosine and Cancer of Stomach

ArticleYear
DNMT1 Gene Expression in Patients with
    TheScientificWorldJournal, 2022, Volume: 2022

    Topics: Adenocarcinoma; Antigens, Bacterial; Bacterial Proteins; Case-Control Studies; Cytosine; DNA, Comple

2022
Decreased 5-hydroxymethylcytosine (5-hmC) is an independent poor prognostic factor in gastric cancer patients.
    Journal of biomedical nanotechnology, 2013, Volume: 9, Issue:9

    Topics: 5-Methylcytosine; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; China; Cytosine; Female; Humans

2013
TET1 exerts its tumor suppressor function by interacting with p53-EZH2 pathway in gastric cancer.
    Journal of biomedical nanotechnology, 2014, Volume: 10, Issue:7

    Topics: 5-Methylcytosine; Animals; Biomarkers, Tumor; Cell Line, Tumor; Cell Proliferation; Cytosine; Dioxyg

2014
Robust quantitative assessments of cytosine modifications and changes in the expressions of related enzymes in gastric cancer.
    Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2015, Volume: 18, Issue:3

    Topics: 5-Methylcytosine; Aged; Chromatography, Liquid; Cytosine; Deoxycytidine; Dioxygenases; DNA-Binding P

2015
Decrease of 5hmC in gastric cancers is associated with TET1 silencing due to with DNA methylation and bivalent histone marks at TET1 CpG island 3'-shore.
    Oncotarget, 2015, Nov-10, Volume: 6, Issue:35

    Topics: 3' Untranslated Regions; 5-Methylcytosine; Chromatin Immunoprecipitation; CpG Islands; Cytosine; DNA

2015
Isocitrate Dehydrogenase 2 Dysfunction Contributes to 5-hydroxymethylcytosine Depletion in Gastric Cancer Cells.
    Anticancer research, 2016, Volume: 36, Issue:8

    Topics: 5-Methylcytosine; Cytosine; DNA Methylation; Female; Humans; Isocitrate Dehydrogenase; Ketoglutaric

2016
Polymorphisms of XRCC1 gene and risk of gastric cardiac adenocarcinoma.
    Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 2009, Volume: 22, Issue:5

    Topics: Adenine; Adenocarcinoma; Adult; Aged; Arginine; Cardia; Case-Control Studies; Codon; Cytosine; DNA R

2009
Loss of 5-hydroxymethylcytosine is accompanied with malignant cellular transformation.
    Cancer science, 2012, Volume: 103, Issue:4

    Topics: 5-Methylcytosine; Cell Line, Tumor; Cell Transformation, Neoplastic; Colorectal Neoplasms; Cytosine;

2012
Control of expression of the lectin-like protein Reg-1 by gastrin: role of the Rho family GTPase RhoA and a C-rich promoter element.
    The Biochemical journal, 2004, Jul-15, Volume: 381, Issue:Pt 2

    Topics: Animals; Base Sequence; Binding Sites; Cytokines; Cytosine; DNA-Binding Proteins; Enzyme Activation;

2004
Association of thymidylate synthase polymorphisms with gastric cancer susceptibility.
    International journal of cancer, 2004, Dec-20, Volume: 112, Issue:6

    Topics: 3' Untranslated Regions; 5' Untranslated Regions; Adult; Aged; Aged, 80 and over; Case-Control Studi

2004
A single nucleotide polymorphism in the MMP-9 promoter affects tumor progression and invasive phenotype of gastric cancer.
    Journal of cancer research and clinical oncology, 2005, Volume: 131, Issue:1

    Topics: Aged; Case-Control Studies; Cytosine; Female; Helicobacter Infections; Helicobacter pylori; Humans;

2005
[On the experimental study of stomach ulcer in rats].
    Voprosy onkologii, 1966, Volume: 12, Issue:8

    Topics: Animals; Cytosine; Male; Pyrimidines; Rats; Stomach Neoplasms; Stomach Ulcer; Thiouracil; Thymine; U

1966
[Nucleotide composition and the methylated cytosine level in the DNA from a cancerous stomach tumor].
    Voprosy onkologii, 1980, Volume: 26, Issue:9

    Topics: 5-Methylcytosine; Adenocarcinoma; Base Composition; Cytosine; DNA, Neoplasm; Duodenal Ulcer; Gastric

1980
Application of a gastric cancer cell line (MKN-28) for anti-adenovirus screening using the MTT method.
    Antiviral research, 1996, Volume: 31, Issue:3

    Topics: Adenine; Adenoviruses, Human; Antiviral Agents; Cidofovir; Cytosine; Drug Evaluation, Preclinical; F

1996
Antitumor activity and novel DNA-self-strand-breaking mechanism of CNDAC (1-(2-C-cyano-2-deoxy-beta-D-arabino-pentofuranosyl) cytosine) and its N4-palmitoyl derivative (CS-682).
    International journal of cancer, 1999, Jul-19, Volume: 82, Issue:2

    Topics: Administration, Oral; Animals; Antimetabolites, Antineoplastic; Arabinonucleosides; Biotransformatio

1999
E-Cadherin gene promoter hypermethylation in primary human gastric carcinomas.
    Journal of the National Cancer Institute, 2000, Apr-05, Volume: 92, Issue:7

    Topics: Blotting, Western; Cadherins; Carcinoma; Cytosine; DNA Primers; DNA, Neoplasm; Down-Regulation; Gene

2000
Aberrant methylation and histone deacetylation of cyclooxygenase 2 in gastric cancer.
    International journal of cancer, 2002, Jan-20, Volume: 97, Issue:3

    Topics: Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Cyclooxygenase 2; Cytosine; Decitabine; DNA

2002
[Analysis of the methylation in CpG island by denaturing high-performance liquid chromatography].
    Zhonghua yi xue za zhi, 2001, Feb-10, Volume: 81, Issue:3

    Topics: Adaptor Proteins, Signal Transducing; Carrier Proteins; Chromatography, High Pressure Liquid; Colore

2001
[Determination of the role of DNA cytosine methylation in human genetic individuality].
    Biulleten' eksperimental'noi biologii i meditsiny, 1991, Volume: 112, Issue:8

    Topics: Cytosine; DNA; DNA Probes; Genes, ras; Genetic Variation; Humans; Stomach Neoplasms; Stomach Ulcer

1991