Page last updated: 2024-10-17

cytosine and Cancer of Skin

cytosine has been researched along with Cancer of Skin in 47 studies

Research Excerpts

ExcerptRelevanceReference
"Because benign nevic cells may also form 'deposits' in lymph nodes (nodal nevus), the pathological evaluation for metastatic melanoma within sentinel lymph nodes can be challenging."5.425-Hydroxymethylcytosine expression in metastatic melanoma versus nodal nevus in sentinel lymph node biopsies. ( Granter, SR; Guo, W; Laga, AC; Lee, JJ; Lian, CG; Murphy, GF; Saavedra, AP; Xu, S; Zhan, Q, 2015)
"Mutations in sunlight-induced melanoma arise from cyclobutane pyrimidine dimers (CPDs), DNA photoproducts that are typically created picoseconds after an ultraviolet (UV) photon is absorbed at thymine or cytosine."3.81Photochemistry. Chemiexcitation of melanin derivatives induces DNA photoproducts long after UV exposure. ( Bacchiocchi, A; Bechara, EJ; Brash, DE; Douki, T; Halaban, R; Mano, CM; Premi, S; Wakamatsu, K; Wallisch, S; Weiner, AB, 2015)
" Adverse drug reactions frequently observed were influenza-like symptoms such as fever (60."2.68[Bropirimine (U-54461S) early phase II clinical studies--to investigate the efficacy and safety of bropirimine treatment on various malignant tumors (urological, hematologic, and dermal cancers)]. ( Furue, H; Ikeda, S; Machida, T; Masaoka, T, 1997)
"Because benign nevic cells may also form 'deposits' in lymph nodes (nodal nevus), the pathological evaluation for metastatic melanoma within sentinel lymph nodes can be challenging."1.425-Hydroxymethylcytosine expression in metastatic melanoma versus nodal nevus in sentinel lymph node biopsies. ( Granter, SR; Guo, W; Laga, AC; Lee, JJ; Lian, CG; Murphy, GF; Saavedra, AP; Xu, S; Zhan, Q, 2015)
"The cause of follicular spicules in multiple myeloma (MM) is not known."1.42Cidofovir gel as treatment of follicular spicules in multiple myeloma. ( Feltkamp, MC; Fouchier, RA; Hajdarbegovic, E; Jones, T; Muhlemann, B; van Boheemen, S, 2015)
"melanoma is 92."1.42Diagnostic utility of 5-hydroxymethylcytosine immunohistochemistry in melanocytic proliferations. ( Burns, KH; Rodić, N; Sharma, R; Taube, JM; Zampella, J, 2015)
"Malignant melanoma, an aggressive skin cancer, is accessible to non-invasive IR radiation based surface probes for its identification and grading."1.35Distinction of malignant melanoma and epidermis using IR micro-spectroscopy and statistical methods. ( Argov, S; Cagnano, E; Hammody, Z; Mordechai, S; Moreh, R; Sahu, RK, 2008)
"Significant deamination occurs at skin cancer mutation sites in the p53 gene."1.30Sequence and time-dependent deamination of cytosine bases in UVB-induced cyclobutane pyrimidine dimers in vivo. ( Dammann, R; Pfeifer, GP; Tu, Y, 1998)
"In human skin cancers, more than 30 % of all mutations in the p53 gene are transitions at dipyrimidines within the sequence context CpG, i."1.30Involvement of 5-methylcytosine in sunlight-induced mutagenesis. ( Li, C; Pfeifer, GP; You, YH, 1999)

Research

Studies (47)

TimeframeStudies, this research(%)All Research%
pre-19902 (4.26)18.7374
1990's14 (29.79)18.2507
2000's14 (29.79)29.6817
2010's15 (31.91)24.3611
2020's2 (4.26)2.80

Authors

AuthorsStudies
Carrier, A1
Desjobert, C1
Ponger, L1
Lamant, L1
Bustos, M1
Torres-Ferreira, J1
Henrique, R1
Jeronimo, C1
Lanfrancone, L1
Delmas, A1
Favre, G1
Daunay, A1
Busato, F1
Hoon, DSB1
Tost, J1
Etievant, C1
Riond, J1
Arimondo, PB1
Lu, C1
Gutierrez-Bayona, NE1
Taylor, JS1
Sugiyama, T1
Chen, Y1
Gambichler, T1
Sand, M1
Skrygan, M1
Uchiyama, R2
Uhara, H2
Uchiyama, A2
Ogawa, E2
Takazawa, Y1
Ashida, A1
Koga, H1
Hayashi, K1
Kiniwa, Y1
Okuyama, R2
Larson, AR1
Dresser, KA1
Zhan, Q3
Lezcano, C1
Woda, BA1
Yosufi, B1
Thompson, JF1
Scolyer, RA1
Mihm, MC2
Shi, YG1
Murphy, GF3
Lian, CG3
Lee, JJ2
Granter, SR1
Laga, AC1
Saavedra, AP1
Guo, W1
Xu, S2
Mikoshiba, Y1
van Boheemen, S2
Jones, T1
Muhlemann, B1
Feltkamp, MC1
Fouchier, RA2
Hajdarbegovic, E2
De Souza, A1
Tinguely, M1
Pfaltz, M1
Burghart, DR1
Kempf, W1
Hosler, GA1
Weibel, L1
Wang, RC1
Premi, S1
Wallisch, S1
Mano, CM1
Weiner, AB1
Bacchiocchi, A1
Wakamatsu, K1
Bechara, EJ1
Halaban, R1
Douki, T1
Brash, DE1
Rodić, N1
Zampella, J1
Sharma, R1
Burns, KH1
Taube, JM1
Cook, M1
Wang, TJ1
Blanco, S1
Bandiera, R1
Popis, M1
Hussain, S1
Lombard, P1
Aleksic, J1
Sajini, A1
Tanna, H1
Cortés-Garrido, R1
Gkatza, N1
Dietmann, S1
Frye, M1
Rünger, TM1
Le Roux-Villet, C1
Michel, L1
Gasnault, J1
Taoufik, Y1
Bachelez, H1
Calista, D2
Toro, JR1
Sanchez, S1
Turiansky, G1
Blauvelt, A1
Watson, RE1
Curtin, GM1
Doolittle, DJ1
Goodman, JI1
Schacke, M1
Meerbach, A1
Thust, R1
Hyckel, P1
Wutzler, P1
Laing, ME1
Dicker, P1
Moloney, FJ1
Ho, WL1
Murphy, GM1
Conlon, P1
Whitehead, AS1
Shields, DC1
Hammody, Z1
Argov, S1
Sahu, RK1
Cagnano, E1
Moreh, R1
Mordechai, S1
Sutter, C1
Greenhalgh, DA1
Ueda, M1
Abhyankar, S1
Ngai, P1
Hennings, H1
Schweizer, J1
Yuspa, SH1
Strickland, JE1
Peng, X1
Lang, CM1
Kreider, JW1
Furue, H1
Machida, T1
Masaoka, T1
Ikeda, S1
Tommasi, S1
Denissenko, MF3
Pfeifer, GP7
Hammoud, Z1
Parenti, DM1
Simon, GL1
Simonart, T2
Noel, JC2
De Dobbeleer, G1
Parent, D1
Van Vooren, JP1
De Clercq, E4
Snoeck, R3
Liekens, S1
Andrei, G1
Vandeputte, M1
Neyts, J1
Zabawski, EJ1
Cockerell, CJ1
Tu, Y1
Dammann, R1
You, YH2
Li, C1
Monti, P1
Inga, A1
Scott, G1
Aprile, A1
Campomenosi, P1
Menichini, P1
Ottaggio, L1
Viaggi, S1
Abbondandolo, A1
Burns, PA1
Fronza, G1
Fife, K1
Gill, J1
Bourboulia, D1
Gazzard, B1
Nelson, M1
Bower, M1
Tang, M1
Redondo, P1
Idoate, M1
Galofré, JC1
Solano, T1
Mazzi, R1
Parisi, SG1
Sarmati, L1
Uccella, I1
Nicastri, E1
Carolo, G1
Gatti, F1
Concia, E1
Andreoni, M1
Van Laethem, Y1
De Maubeuge, J1
Clumeck, N1
Cavalieri, E1
Calvin, M1

Reviews

5 reviews available for cytosine and Cancer of Skin

ArticleYear
Topical cidofovir for the treatment of dermatologic conditions: verruca, condyloma, intraepithelial neoplasia, herpes simplex and its potential use in smallpox.
    Dermatologic clinics, 2003, Volume: 21, Issue:2

    Topics: Administration, Cutaneous; Administration, Topical; Antiviral Agents; Carcinoma in Situ; Carcinoma,

2003
Formation and repair of DNA lesions in the p53 gene: relation to cancer mutations?
    Environmental and molecular mutagenesis, 1998, Volume: 31, Issue:3

    Topics: 5-Methylcytosine; Animals; Benzo(a)pyrene; Breast Neoplasms; Carcinogens, Environmental; Colonic Neo

1998
Topical and intralesional cidofovir: a review of pharmacology and therapeutic effects.
    Journal of the American Academy of Dermatology, 1998, Volume: 39, Issue:5 Pt 1

    Topics: Administration, Cutaneous; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antiviral Agents;

1998
Mutation hotspots and DNA methylation.
    Current topics in microbiology and immunology, 2000, Volume: 249

    Topics: 5-Methylcytosine; Carcinogens; CpG Islands; Cytosine; DNA Methylation; Genes, p53; Genes, Tumor Supp

2000
p53 mutational spectra and the role of methylated CpG sequences.
    Mutation research, 2000, May-30, Volume: 450, Issue:1-2

    Topics: 5-Methylcytosine; Carcinogens; CpG Islands; Cytosine; DNA Methylation; DNA Repair; DNA, Neoplasm; Ge

2000

Trials

1 trial available for cytosine and Cancer of Skin

ArticleYear
[Bropirimine (U-54461S) early phase II clinical studies--to investigate the efficacy and safety of bropirimine treatment on various malignant tumors (urological, hematologic, and dermal cancers)].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1997, Volume: 24, Issue:1

    Topics: Adult; Aged; Anorexia; Antineoplastic Agents; Cytosine; Drug Administration Schedule; Female; Fever;

1997

Other Studies

41 other studies available for cytosine and Cancer of Skin

ArticleYear
DNA methylome combined with chromosome cluster-oriented analysis provides an early signature for cutaneous melanoma aggressiveness.
    eLife, 2022, 09-20, Volume: 11

    Topics: Animals; Chromosomes; CpG Islands; Cytosine; DNA Methylation; Epigenesis, Genetic; Epigenome; Gene E

2022
The effect of flanking bases on direct and triplet sensitized cyclobutane pyrimidine dimer formation in DNA depends on the dipyrimidine, wavelength and the photosensitizer.
    Nucleic acids research, 2021, 05-07, Volume: 49, Issue:8

    Topics: 3' Flanking Region; 5' Flanking Region; Base Sequence; Cytosine; DNA; Humans; Melanocytes; Mutagenes

2021
Biochemical reconstitution of UV-induced mutational processes.
    Nucleic acids research, 2019, 07-26, Volume: 47, Issue:13

    Topics: 5-Methylcytosine; Cell-Free System; Cytosine; Deamination; DNA Damage; DNA Replication; DNA-Cytosine

2019
Loss of 5-hydroxymethylcytosine and ten-eleven translocation 2 protein expression in malignant melanoma.
    Melanoma research, 2013, Volume: 23, Issue:3

    Topics: 5-Methylcytosine; Biomarkers, Tumor; Cytosine; Dioxygenases; Disease Progression; DNA-Binding Protei

2013
5-Hydroxymethylcytosine as a useful marker to differentiate between malignant melanomas and benign melanocytic nevi.
    Journal of dermatological science, 2014, Volume: 73, Issue:2

    Topics: 5-Methylcytosine; Adult; Aged; Aged, 80 and over; Biomarkers; CpG Islands; Cytosine; DNA Methylation

2014
Loss of 5-hydroxymethylcytosine correlates with increasing morphologic dysplasia in melanocytic tumors.
    Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 2014, Volume: 27, Issue:7

    Topics: 5-Methylcytosine; Adult; Aged; Aged, 80 and over; Cytosine; DNA Methylation; Female; Humans; Male; M

2014
5-Hydroxymethylcytosine expression in metastatic melanoma versus nodal nevus in sentinel lymph node biopsies.
    Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 2015, Volume: 28, Issue:2

    Topics: 5-Methylcytosine; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Cytosine; Female; Fluorescent A

2015
5-Hydroxymethylcytosine is a useful marker to differentiate between dermatofibrosarcoma protuberans and dermatofibroma.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2016, Volume: 30, Issue:1

    Topics: 5-Methylcytosine; Biomarkers, Tumor; Cytosine; Dermatofibrosarcoma; Humans; Skin Neoplasms

2016
Cidofovir gel as treatment of follicular spicules in multiple myeloma.
    JAMA dermatology, 2015, Volume: 151, Issue:1

    Topics: Aged; Antiviral Agents; Carcinoma, Merkel Cell; Cidofovir; Cytosine; Gels; Hair Follicle; Humans; Ma

2015
Loss of expression of 5-hydroxymethylcytosine in CD30-positive cutaneous lymphoproliferative disorders.
    Journal of cutaneous pathology, 2014, Volume: 41, Issue:12

    Topics: 5-Methylcytosine; Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Case-Control Studie

2014
The cause of follicular spicules in multiple myeloma.
    JAMA dermatology, 2015, Volume: 151, Issue:4

    Topics: Carcinoma, Merkel Cell; Cytosine; Humans; Male; Multiple Myeloma; Organophosphonates; Skin Neoplasms

2015
The cause of follicular spicules in multiple myeloma-reply.
    JAMA dermatology, 2015, Volume: 151, Issue:4

    Topics: Carcinoma, Merkel Cell; Cytosine; Humans; Male; Multiple Myeloma; Organophosphonates; Skin Neoplasms

2015
Photochemistry. Chemiexcitation of melanin derivatives induces DNA photoproducts long after UV exposure.
    Science (New York, N.Y.), 2015, Feb-20, Volume: 347, Issue:6224

    Topics: Animals; Cells, Cultured; Cytosine; DNA; DNA Damage; Energy Transfer; Humans; Melanins; Melanocytes;

2015
Diagnostic utility of 5-hydroxymethylcytosine immunohistochemistry in melanocytic proliferations.
    Journal of cutaneous pathology, 2015, Volume: 42, Issue:11

    Topics: 5-Methylcytosine; Cytosine; Diagnosis, Differential; Humans; Immunohistochemistry; Lymph Nodes; Lymp

2015
Loss of the epigenetic mark, 5-Hydroxymethylcytosine, correlates with small cell/nevoid subpopulations and assists in microstaging of human melanoma.
    Oncotarget, 2015, Nov-10, Volume: 6, Issue:35

    Topics: 5-Methylcytosine; Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Carcinoma, Small Ce

2015
Stem cell function and stress response are controlled by protein synthesis.
    Nature, 2016, 06-16, Volume: 534, Issue:7607

    Topics: Animals; Cell Differentiation; Cell Proliferation; Cell Transformation, Neoplastic; Cytosine; Female

2016
C-->T transition mutations are not solely UVB-signature mutations, because they are also generated by UVA.
    The Journal of investigative dermatology, 2008, Volume: 128, Issue:9

    Topics: Animals; Carcinoma, Squamous Cell; Cells, Cultured; Cytosine; DNA; DNA Damage; DNA, Neoplasm; Mice;

2008
Progressive multifocal leucoencephalopathy in a patient with Sézary syndrome.
    The British journal of dermatology, 2010, Volume: 163, Issue:5

    Topics: Antiviral Agents; CD4-Positive T-Lymphocytes; Cidofovir; Cytarabine; Cytosine; Fatal Outcome; Flow C

2010
Regression of a cutaneous melanoma metastasis after intralesional cidofovir.
    Melanoma research, 2003, Volume: 13, Issue:2

    Topics: Antineoplastic Agents; Cidofovir; Cytosine; Humans; Lymphatic Metastasis; Male; Melanoma; Middle Age

2003
Progressive alterations in global and GC-rich DNA methylation during tumorigenesis.
    Toxicological sciences : an official journal of the Society of Toxicology, 2003, Volume: 75, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogenicity Tests; Carcinogens; Cytosine; DNA Methyla

2003
Establishment and cidofovir sensitivity of a cell line from a heart transplant recipient with multiple cutaneous tumors.
    Neoplasma, 2003, Volume: 50, Issue:3

    Topics: Aged; Antiviral Agents; Biopsy; Cell Division; Chromosome Aberrations; Cidofovir; Cytosine; DNA, Vir

2003
Treatment of lentigo maligna with topical 1% cidofovir.
    The British journal of dermatology, 2007, Volume: 157, Issue:2

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Cidofovir; Cytosine; Facial Neoplasms; Female; Human

2007
Association of methylenetetrahydrofolate reductase polymorphism and the risk of squamous cell carcinoma in renal transplant patients.
    Transplantation, 2007, Jul-15, Volume: 84, Issue:1

    Topics: Alleles; Carcinoma, Squamous Cell; Cytosine; Female; Genetic Predisposition to Disease; Genotype; Gu

2007
Distinction of malignant melanoma and epidermis using IR micro-spectroscopy and statistical methods.
    The Analyst, 2008, Volume: 133, Issue:3

    Topics: Biomarkers, Tumor; Cytosine; Discriminant Analysis; DNA, Neoplasm; Epidermis; Guanine; Humans; Melan

2008
SENCAR mouse skin tumors produced by promotion alone have A to G mutations in codon 61 of the c-rasHa gene.
    Carcinogenesis, 1994, Volume: 15, Issue:9

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenine; Animals; Base Sequence; Cocarcinogenesis; Codon; Cytosine

1994
Methylation of cottontail rabbit papillomavirus DNA and tissue-specific expression in transgenic rabbits.
    Virus research, 1995, Volume: 35, Issue:1

    Topics: 5-Methylcytosine; Animals; Animals, Genetically Modified; Cottontail rabbit papillomavirus; Cytosine

1995
Sunlight induces pyrimidine dimers preferentially at 5-methylcytosine bases.
    Cancer research, 1997, Nov-01, Volume: 57, Issue:21

    Topics: 5-Methylcytosine; Codon; Cytosine; Genes, p53; Humans; Keratinocytes; Methylation; Mutation; Neoplas

1997
Abatement of cutaneous Kaposi's sarcoma associated with cidofovir treatment.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1998, Volume: 26, Issue:5

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis

1998
Treatment of classical Kaposi's sarcoma with intralesional injections of cidofovir: report of a case.
    Journal of medical virology, 1998, Volume: 55, Issue:3

    Topics: Aged; Antiviral Agents; Cidofovir; Cytosine; DNA, Viral; Herpesvirus 8, Human; Humans; Injections, I

1998
Potent inhibition of hemangioma formation in rats by the acyclic nucleoside phosphonate analogue cidofovir.
    Cancer research, 1998, Jun-15, Volume: 58, Issue:12

    Topics: Animals; Antiviral Agents; Body Weight; Brain Neoplasms; Cidofovir; Cytosine; Hemangioma; Incidence;

1998
Sequence and time-dependent deamination of cytosine bases in UVB-induced cyclobutane pyrimidine dimers in vivo.
    Journal of molecular biology, 1998, Nov-27, Volume: 284, Issue:2

    Topics: Carbon-Oxygen Lyases; Cytosine; Deamination; Deoxyribodipyrimidine Photo-Lyase; Deoxyribonuclease IV

1998
Abatement of cutaneous Kaposi's sarcoma associated with cidofovir treatment.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1998, Volume: 27, Issue:6

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytosine; Humans; Organophosphon

1998
Involvement of 5-methylcytosine in sunlight-induced mutagenesis.
    Journal of molecular biology, 1999, Oct-29, Volume: 293, Issue:3

    Topics: 5-Methylcytosine; Animals; Bacterial Proteins; Base Sequence; Cells, Cultured; CpG Islands; Cytosine

1999
5-methylcytosine at HpaII sites in p53 is not hypermutable after UVC irradiation.
    Mutation research, 1999, Dec-16, Volume: 431, Issue:1

    Topics: 5-Methylcytosine; Codon; CpG Islands; Cytosine; Deoxyribonuclease HpaII; DNA Methylation; Humans; Mu

1999
Cidofovir for the treatment of Kaposi's sarcoma in an HIV-negative homosexual man.
    The British journal of dermatology, 1999, Volume: 141, Issue:6

    Topics: Adult; Antiviral Agents; Cidofovir; Cytosine; HIV Seronegativity; Humans; Male; Organophosphonates;

1999
Cidofovir inhibits growth of B16 melanoma cells in vivo.
    The British journal of dermatology, 2000, Volume: 143, Issue:4

    Topics: Animals; Antineoplastic Agents; Body Weight; Cidofovir; Cytosine; Dose-Response Relationship, Drug;

2000
Similarities in sunlight-induced mutational spectra of CpG-methylated transgenes and the p53 gene in skin cancer point to an important role of 5-methylcytosine residues in solar UV mutagenesis.
    Journal of molecular biology, 2001, Jan-19, Volume: 305, Issue:3

    Topics: 5-Methylcytosine; Animals; Bacterial Proteins; Base Sequence; Cell Line; CpG Islands; Cytosine; DNA

2001
Efficacy of cidofovir on human herpesvirus 8 viraemia and Kaposi's sarcoma progression in two patients with AIDS.
    AIDS (London, England), 2001, Oct-19, Volume: 15, Issue:15

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytosine; Disease Progression; D

2001
Treatment of a bowenoid papulosis of the penis with local applications of cidofovir in a patient with acquired immunodeficiency syndrome.
    Archives of internal medicine, 2001, Oct-22, Volume: 161, Issue:19

    Topics: Acquired Immunodeficiency Syndrome; Administration, Topical; Adult; Antiviral Agents; Bowen's Diseas

2001
[Molecular origin of the effects of light on nucleic acid metabolism].
    Folia haematologica (Leipzig, Germany : 1928), 1974, Volume: 101, Issue:5

    Topics: Animals; Bacteria; Bacteriophages; Cytosine; DNA; Humans; Methylene Blue; Mice; Nucleic Acid Renatur

1974
Photochemical coupling of benzo(a)pyrene with 1-methylcytosine; photoenhancement of carcinogenicity.
    Photochemistry and photobiology, 1971, Volume: 14, Issue:5

    Topics: Animals; Benzopyrenes; Carcinogens; Cytosine; Light; Mice; Neoplasms, Experimental; Photochemistry;

1971