Page last updated: 2024-10-17

cytosine and Cancer of Prostate

cytosine has been researched along with Cancer of Prostate in 28 studies

Research Excerpts

ExcerptRelevanceReference
"In addition, mean residual tumor weights (expressed in grams) after 20-22 days were: Group 1, 12."5.30Bropirimine as neoadjuvant therapy decreases residual disease and expression of markers PCNA and TGF-beta 1 in a rat orthotopic prostate adenocarcinoma. ( Bridges, P; Brown, J; Di Domenico, D; Guinan, P; Lievano, G; Rubenstein, M; Shaw, M, 1997)
"AR is also a critical mediator of prostate cancer promotion, conferring growth signals to prostate cancer cells throughout the natural history of the disease."2.41Molecular biology of the androgen receptor. ( Gelmann, EP, 2002)
"Prognostic tools for prostate cancer (PC) are inadequate and new molecular biomarkers may improve risk stratification."1.48Dysregulation and prognostic potential of 5-methylcytosine (5mC), 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and 5-carboxylcytosine (5caC) levels in prostate cancer. ( Borre, M; Høyer, S; Lynnerup, AS; Storebjerg, TM; Strand, SH; Sørensen, KD; Ørntoft, TF, 2018)
"Current diagnostic tools for prostate cancer lack specificity and sensitivity for detecting very early lesions."1.46Genome-wide DNA methylation measurements in prostate tissues uncovers novel prostate cancer diagnostic biomarkers and transcription factor binding patterns. ( Absher, DM; Brooks, JD; Burwell, TC; Cooper, SJ; Davis, NS; Gulzar, ZG; Gunther, DS; Kirby, MK; Lasseigne, BN; Myers, RM; Ramaker, RC; Roberts, BS, 2017)
"With these fluorescent tools, tumors and metastasis in host organs can be externally imaged down to the single-cell level."1.33Orthotopic metastatic (MetaMouse) models for discovery and development of novel chemotherapy. ( Hoffman, RM, 2005)
"The formation or progression of prostate cancer is presumed to be associated with a polymorphism of the vascular endothelial growth factor (VEGF) gene."1.32Vascular endothelial growth factor gene-460 C/T polymorphism is a biomarker for prostate cancer. ( Chen, HY; Chen, WC; Lin, CC; Tsai, FJ; Wu, HC, 2003)
"Nuclear extracts from PC-3 and DU-145 prostate cancer cell lines are defective in the incision of 8-oxoG, 5OHC and thymine glycol (TG) relative to the non-malignant prostate cell line."1.32Cellular repair of oxidatively induced DNA base lesions is defective in prostate cancer cell lines, PC-3 and DU-145. ( Dizdaroglu, M; Evans, MK; Jaruga, P; Lohani, A; Nyaga, SG; Trzeciak, AR, 2004)
"In the prostate cancer lines where MT-I was suppressed, glutathione-S-transferase-pi (GST-pi) was expressed."1.31Suppression of metallothionein-I/II expression and its probable molecular mechanisms. ( Ghoshal, K; Jacob, ST; Majumder, S, 2002)
"In contrast, Du145 and PC3 prostate cancer cells express the GSTP1 gene and exhibit methylated and unmethylated GSTP1 alleles."1.31Cytosine methylation represses glutathione S-transferase P1 (GSTP1) gene expression in human prostate cancer cells. ( Bashambu, M; Singal, R; van Wert, J, 2001)
"A troxacitabine-resistant prostate cancer subline (DU145(R); 6300-fold) that exhibited reduced uptake of troxacitabine was cross-resistant to both gemcitabine (350-fold) and cytarabine (300-fold)."1.31Mechanisms of uptake and resistance to troxacitabine, a novel deoxycytidine nucleoside analogue, in human leukemic and solid tumor cell lines. ( Cass, CE; Clarke, ML; Gourdeau, H; Jolivet, J; Lafrenière, RG; Lee, N; Mackey, JR; Mowles, D; Ouellet, F; Richard, A; Selner, M; Young, JD, 2001)
"Bropirimine is an oral immunostimulant found to have efficacy in human transitional cell carcinoma in situ following the initial discovery of its antitumor activity against the murine bladder cancer MBT-2."1.30Oral bropirimine immunotherapy of rodent prostate cancer. ( Sarosdy, MF, 1997)
"In addition, mean residual tumor weights (expressed in grams) after 20-22 days were: Group 1, 12."1.30Bropirimine as neoadjuvant therapy decreases residual disease and expression of markers PCNA and TGF-beta 1 in a rat orthotopic prostate adenocarcinoma. ( Bridges, P; Brown, J; Di Domenico, D; Guinan, P; Lievano, G; Rubenstein, M; Shaw, M, 1997)
"Established prostate cancer-derived cell lines LnCAP, DU-145, and PC-3 demonstrated NQO1 wild-type genotype."1.30609 C --> T polymorphism in NAD(P)H:quinone oxidoreductase gene in patients with prostatic adenocarcinoma or benign prostatic hyperplasia. ( Borkowsi, M; Hillenbrand, M; Schuff-Werner, P; Seiter, H; Steiner, M, 1999)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.57)18.7374
1990's9 (32.14)18.2507
2000's11 (39.29)29.6817
2010's6 (21.43)24.3611
2020's1 (3.57)2.80

Authors

AuthorsStudies
Gakis, G1
Perner, S1
Stenzl, A1
Renninger, M1
Kirby, MK1
Ramaker, RC1
Roberts, BS1
Lasseigne, BN1
Gunther, DS1
Burwell, TC1
Davis, NS1
Gulzar, ZG1
Absher, DM1
Cooper, SJ1
Brooks, JD1
Myers, RM1
Pistore, C1
Giannoni, E1
Colangelo, T1
Rizzo, F1
Magnani, E1
Muccillo, L1
Giurato, G1
Mancini, M1
Rizzo, S1
Riccardi, M1
Sahnane, N1
Del Vescovo, V1
Kishore, K1
Mandruzzato, M1
Macchi, F1
Pelizzola, M1
Denti, MA1
Furlan, D1
Weisz, A1
Colantuoni, V1
Chiarugi, P1
Bonapace, IM1
Storebjerg, TM1
Strand, SH1
Høyer, S1
Lynnerup, AS1
Borre, M1
Ørntoft, TF1
Sørensen, KD1
Takayama, K1
Misawa, A1
Suzuki, T1
Takagi, K1
Hayashizaki, Y1
Fujimura, T1
Homma, Y1
Takahashi, S1
Urano, T1
Inoue, S1
Haffner, MC1
Chaux, A1
Meeker, AK1
Esopi, DM1
Gerber, J1
Pellakuru, LG1
Toubaji, A1
Argani, P1
Iacobuzio-Donahue, C1
Nelson, WG1
Netto, GJ1
De Marzo, AM1
Yegnasubramanian, S1
Cortese, R1
Kwan, A1
Lalonde, E1
Bryzgunova, O1
Bondar, A1
Wu, Y1
Gordevicius, J1
Park, M1
Oh, G1
Kaminsky, Z1
Tverkuviene, J1
Laurinavicius, A1
Jankevicius, F1
Sendorek, DH1
Haider, S1
Wang, SC1
Jarmalaite, S1
Laktionov, P1
Boutros, PC1
Petronis, A1
Jacob, ST1
Majumder, S1
Ghoshal, K1
Pakneshan, P1
Xing, RH1
Rabbani, SA2
Lin, CC1
Wu, HC1
Tsai, FJ1
Chen, HY1
Chen, WC1
Trzeciak, AR1
Nyaga, SG1
Jaruga, P1
Lohani, A1
Dizdaroglu, M1
Evans, MK1
Powell, IJ1
Land, SJ1
Dey, J1
Heilbrun, LK1
Hughes, MR1
Sakr, W1
Everson, RB1
Hoffman, RM1
Grove, KL2
Guo, X1
Liu, SH1
Gao, Z1
Chu, CK1
Cheng, YC2
Sarosdy, MF2
Higdon, AL1
Demoor, CA1
Lievano, G1
Di Domenico, D1
Brown, J1
Bridges, P1
Rubenstein, M2
Shaw, M2
Guinan, P2
Akaza, H1
Ratanawong, S1
Chou, P1
Ray, V1
Mirochnik, Y1
Slobodskoy, L1
Harakidas, P1
Bowlin, T1
Attardo, G1
Steiner, M1
Hillenbrand, M1
Borkowsi, M1
Seiter, H1
Schuff-Werner, P1
Tamada, H1
Kitazawa, R1
Gohji, K1
Kitazawa, S1
Singal, R1
van Wert, J1
Bashambu, M1
Gourdeau, H1
Clarke, ML1
Ouellet, F1
Mowles, D1
Selner, M1
Richard, A1
Lee, N1
Mackey, JR1
Young, JD1
Jolivet, J1
Lafrenière, RG1
Cass, CE1
Gilbert, SM1
Benson, MC1
McKiernan, JM1
Gelmann, EP1
Bedford, MT1
van Helden, PD1

Reviews

3 reviews available for cytosine and Cancer of Prostate

ArticleYear
[Development of new drugs for urological cancers].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1997, Volume: 24, Issue:13

    Topics: Androgen Antagonists; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Carcinoma, Renal Cell;

1997
Linkage disequilibrium between the androgen receptor gene CAG and GGC repeats in the African-American population.
    Current urology reports, 2002, Volume: 3, Issue:3

    Topics: Adenine; Black People; Cytosine; Guanosine; Humans; Linkage Disequilibrium; Male; Prostatic Neoplasm

2002
Molecular biology of the androgen receptor.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Jul-01, Volume: 20, Issue:13

    Topics: Adenine; Animals; Cytosine; Guanine; Humans; Male; Prostatic Neoplasms; Receptors, Androgen; Risk; T

2002

Other Studies

25 other studies available for cytosine and Cancer of Prostate

ArticleYear
The CAG-triplet in the androgen receptor gene and single-nucleotide polymorphisms in androgen pathway genes in patients with concomitant bladder and prostate cancer.
    Urologic oncology, 2022, Volume: 40, Issue:5

    Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Adenine; Androgens; Cytosine; Guanine; Humans; Male; Membrane

2022
Genome-wide DNA methylation measurements in prostate tissues uncovers novel prostate cancer diagnostic biomarkers and transcription factor binding patterns.
    BMC cancer, 2017, 04-17, Volume: 17, Issue:1

    Topics: Adult; Aged; Biomarkers, Tumor; Cytosine; DNA Methylation; Enhancer of Zeste Homolog 2 Protein; Huma

2017
DNA methylation variations are required for epithelial-to-mesenchymal transition induced by cancer-associated fibroblasts in prostate cancer cells.
    Oncogene, 2017, 10-05, Volume: 36, Issue:40

    Topics: Cancer-Associated Fibroblasts; Cell Line, Tumor; Cell Transformation, Neoplastic; Culture Media, Con

2017
Dysregulation and prognostic potential of 5-methylcytosine (5mC), 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and 5-carboxylcytosine (5caC) levels in prostate cancer.
    Clinical epigenetics, 2018, 08-07, Volume: 10, Issue:1

    Topics: 5-Methylcytosine; Adult; Aged; Cytosine; DNA Methylation; Epigenesis, Genetic; Gene Expression Regul

2018
TET2 repression by androgen hormone regulates global hydroxymethylation status and prostate cancer progression.
    Nature communications, 2015, Sep-25, Volume: 6

    Topics: 5-Methylcytosine; Aged; Androgens; Animals; Blotting, Western; Cell Line, Tumor; Cell Proliferation;

2015
Global 5-hydroxymethylcytosine content is significantly reduced in tissue stem/progenitor cell compartments and in human cancers.
    Oncotarget, 2011, Volume: 2, Issue:8

    Topics: 5-Methylcytosine; Adenocarcinoma; Animals; Breast Neoplasms; Carcinoma, Ductal, Breast; Cell Differe

2011
Epigenetic markers of prostate cancer in plasma circulating DNA.
    Human molecular genetics, 2012, Aug-15, Volume: 21, Issue:16

    Topics: Aged; Biomarkers, Tumor; Case-Control Studies; Centromere; Chromosomes, Human, Pair 10; Cytosine; DN

2012
Suppression of metallothionein-I/II expression and its probable molecular mechanisms.
    Environmental health perspectives, 2002, Volume: 110 Suppl 5

    Topics: Animals; Carcinoma, Hepatocellular; CCAAT-Enhancer-Binding Proteins; Cytosine; DNA-Binding Proteins;

2002
Methylation status of uPA promoter as a molecular mechanism regulating prostate cancer invasion and growth in vitro and in vivo.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2003, Volume: 17, Issue:9

    Topics: Animals; Base Sequence; Blotting, Southern; Cell Division; Cytosine; DNA Methylation; Gene Expressio

2003
Vascular endothelial growth factor gene-460 C/T polymorphism is a biomarker for prostate cancer.
    Urology, 2003, Volume: 62, Issue:2

    Topics: Aged; Aged, 80 and over; Biomarkers, Tumor; Cytosine; Endothelial Growth Factors; Genetic Markers; H

2003
Cellular repair of oxidatively induced DNA base lesions is defective in prostate cancer cell lines, PC-3 and DU-145.
    Carcinogenesis, 2004, Volume: 25, Issue:8

    Topics: Adenine; Antioxidants; Blotting, Western; Catalase; Cell Division; Cell Line, Tumor; Cell Nucleus; C

2004
The impact of CAG repeats in exon 1 of the androgen receptor on disease progression after prostatectomy.
    Cancer, 2005, Feb-01, Volume: 103, Issue:3

    Topics: Adenine; Age Factors; Aged; Black People; Cytosine; Disease Progression; Exons; Genotype; Guanine; H

2005
Orthotopic metastatic (MetaMouse) models for discovery and development of novel chemotherapy.
    Methods in molecular medicine, 2005, Volume: 111

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Camptothecin; Cisplatin; Colonic Neoplasms;

2005
Anticancer activity of beta-L-dioxolane-cytidine, a novel nucleoside analogue with the unnatural L configuration.
    Cancer research, 1995, Jul-15, Volume: 55, Issue:14

    Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Division; Colonic Neoplasms; Cytarab

1995
In vivo antitumor activity of bropirimine against PAIII and Dunning MAT-LyLu rodent prostate cancers.
    The Journal of urology, 1996, Volume: 155, Issue:6

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cytosine; Male; Neoplasm Transplantation; Prostatic

1996
Uptake and metabolism of the new anticancer compound beta-L-(-)-dioxolane-cytidine in human prostate carcinoma DU-145 cells.
    Cancer research, 1996, Sep-15, Volume: 56, Issue:18

    Topics: Antimetabolites, Antineoplastic; Biological Transport; Cell Line; Cytarabine; Cytosine; Dioxolanes;

1996
Oral bropirimine immunotherapy of rodent prostate cancer.
    European urology, 1997, Volume: 31 Suppl 1

    Topics: Adjuvants, Immunologic; Administration, Oral; Animals; Antineoplastic Agents; Cell Division; Cytosin

1997
Bropirimine as neoadjuvant therapy decreases residual disease and expression of markers PCNA and TGF-beta 1 in a rat orthotopic prostate adenocarcinoma.
    Methods and findings in experimental and clinical pharmacology, 1997, Volume: 19, Issue:4

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Biomarkers, Tumor; Cytosine; Down-Regulation; Gene E

1997
Paclitaxel, bropirimine and linomide: effect on growth inhibition in a murine prostate cancer model by different growth regulatory mechanisms.
    Methods and findings in experimental and clinical pharmacology, 1998, Volume: 20, Issue:2

    Topics: Animals; Antineoplastic Agents; Cell Division; Cytosine; Hydroxyquinolines; Immunohistochemistry; Ma

1998
Effect of nucleoside analogue BCH-4556 on prostate cancer growth and metastases in vitro and in vivo.
    Cancer research, 1998, Aug-01, Volume: 58, Issue:15

    Topics: Animals; Antineoplastic Agents; Bone Neoplasms; Cell Division; Cytosine; Dioxolanes; Doxorubicin; Ma

1998
609 C --> T polymorphism in NAD(P)H:quinone oxidoreductase gene in patients with prostatic adenocarcinoma or benign prostatic hyperplasia.
    Cancer letters, 1999, Jan-08, Volume: 135, Issue:1

    Topics: Adenocarcinoma; Alleles; Cytosine; Female; Genes, Neoplasm; Genotype; Humans; Male; NAD(P)H Dehydrog

1999
Epigenetic regulation of human bone morphogenetic protein 6 gene expression in prostate cancer.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2001, Volume: 16, Issue:3

    Topics: Aged; Blotting, Northern; Bone Morphogenetic Protein 2; Bone Morphogenetic Protein 6; Bone Morphogen

2001
Cytosine methylation represses glutathione S-transferase P1 (GSTP1) gene expression in human prostate cancer cells.
    Cancer research, 2001, Jun-15, Volume: 61, Issue:12

    Topics: Azacitidine; Base Sequence; Cytosine; Decitabine; DNA Methylation; Enzyme Inhibitors; Gene Expressio

2001
Mechanisms of uptake and resistance to troxacitabine, a novel deoxycytidine nucleoside analogue, in human leukemic and solid tumor cell lines.
    Cancer research, 2001, Oct-01, Volume: 61, Issue:19

    Topics: Amino Acid Sequence; Antineoplastic Agents; Biological Transport; Carrier Proteins; Cytarabine; Cyti

2001
Hypomethylation of DNA in pathological conditions of the human prostate.
    Cancer research, 1987, Oct-15, Volume: 47, Issue:20

    Topics: 5-Methylcytosine; Adult; Aged; Aged, 80 and over; Cytosine; DNA; Humans; Male; Mathematics; Methylat

1987