cytosine has been researched along with Cancer of Prostate in 28 studies
Excerpt | Relevance | Reference |
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"In addition, mean residual tumor weights (expressed in grams) after 20-22 days were: Group 1, 12." | 5.30 | Bropirimine as neoadjuvant therapy decreases residual disease and expression of markers PCNA and TGF-beta 1 in a rat orthotopic prostate adenocarcinoma. ( Bridges, P; Brown, J; Di Domenico, D; Guinan, P; Lievano, G; Rubenstein, M; Shaw, M, 1997) |
"AR is also a critical mediator of prostate cancer promotion, conferring growth signals to prostate cancer cells throughout the natural history of the disease." | 2.41 | Molecular biology of the androgen receptor. ( Gelmann, EP, 2002) |
"Prognostic tools for prostate cancer (PC) are inadequate and new molecular biomarkers may improve risk stratification." | 1.48 | Dysregulation and prognostic potential of 5-methylcytosine (5mC), 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and 5-carboxylcytosine (5caC) levels in prostate cancer. ( Borre, M; Høyer, S; Lynnerup, AS; Storebjerg, TM; Strand, SH; Sørensen, KD; Ørntoft, TF, 2018) |
"Current diagnostic tools for prostate cancer lack specificity and sensitivity for detecting very early lesions." | 1.46 | Genome-wide DNA methylation measurements in prostate tissues uncovers novel prostate cancer diagnostic biomarkers and transcription factor binding patterns. ( Absher, DM; Brooks, JD; Burwell, TC; Cooper, SJ; Davis, NS; Gulzar, ZG; Gunther, DS; Kirby, MK; Lasseigne, BN; Myers, RM; Ramaker, RC; Roberts, BS, 2017) |
"With these fluorescent tools, tumors and metastasis in host organs can be externally imaged down to the single-cell level." | 1.33 | Orthotopic metastatic (MetaMouse) models for discovery and development of novel chemotherapy. ( Hoffman, RM, 2005) |
"The formation or progression of prostate cancer is presumed to be associated with a polymorphism of the vascular endothelial growth factor (VEGF) gene." | 1.32 | Vascular endothelial growth factor gene-460 C/T polymorphism is a biomarker for prostate cancer. ( Chen, HY; Chen, WC; Lin, CC; Tsai, FJ; Wu, HC, 2003) |
"Nuclear extracts from PC-3 and DU-145 prostate cancer cell lines are defective in the incision of 8-oxoG, 5OHC and thymine glycol (TG) relative to the non-malignant prostate cell line." | 1.32 | Cellular repair of oxidatively induced DNA base lesions is defective in prostate cancer cell lines, PC-3 and DU-145. ( Dizdaroglu, M; Evans, MK; Jaruga, P; Lohani, A; Nyaga, SG; Trzeciak, AR, 2004) |
"In the prostate cancer lines where MT-I was suppressed, glutathione-S-transferase-pi (GST-pi) was expressed." | 1.31 | Suppression of metallothionein-I/II expression and its probable molecular mechanisms. ( Ghoshal, K; Jacob, ST; Majumder, S, 2002) |
"In contrast, Du145 and PC3 prostate cancer cells express the GSTP1 gene and exhibit methylated and unmethylated GSTP1 alleles." | 1.31 | Cytosine methylation represses glutathione S-transferase P1 (GSTP1) gene expression in human prostate cancer cells. ( Bashambu, M; Singal, R; van Wert, J, 2001) |
"A troxacitabine-resistant prostate cancer subline (DU145(R); 6300-fold) that exhibited reduced uptake of troxacitabine was cross-resistant to both gemcitabine (350-fold) and cytarabine (300-fold)." | 1.31 | Mechanisms of uptake and resistance to troxacitabine, a novel deoxycytidine nucleoside analogue, in human leukemic and solid tumor cell lines. ( Cass, CE; Clarke, ML; Gourdeau, H; Jolivet, J; Lafrenière, RG; Lee, N; Mackey, JR; Mowles, D; Ouellet, F; Richard, A; Selner, M; Young, JD, 2001) |
"Bropirimine is an oral immunostimulant found to have efficacy in human transitional cell carcinoma in situ following the initial discovery of its antitumor activity against the murine bladder cancer MBT-2." | 1.30 | Oral bropirimine immunotherapy of rodent prostate cancer. ( Sarosdy, MF, 1997) |
"In addition, mean residual tumor weights (expressed in grams) after 20-22 days were: Group 1, 12." | 1.30 | Bropirimine as neoadjuvant therapy decreases residual disease and expression of markers PCNA and TGF-beta 1 in a rat orthotopic prostate adenocarcinoma. ( Bridges, P; Brown, J; Di Domenico, D; Guinan, P; Lievano, G; Rubenstein, M; Shaw, M, 1997) |
"Established prostate cancer-derived cell lines LnCAP, DU-145, and PC-3 demonstrated NQO1 wild-type genotype." | 1.30 | 609 C --> T polymorphism in NAD(P)H:quinone oxidoreductase gene in patients with prostatic adenocarcinoma or benign prostatic hyperplasia. ( Borkowsi, M; Hillenbrand, M; Schuff-Werner, P; Seiter, H; Steiner, M, 1999) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (3.57) | 18.7374 |
1990's | 9 (32.14) | 18.2507 |
2000's | 11 (39.29) | 29.6817 |
2010's | 6 (21.43) | 24.3611 |
2020's | 1 (3.57) | 2.80 |
Authors | Studies |
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Gakis, G | 1 |
Perner, S | 1 |
Stenzl, A | 1 |
Renninger, M | 1 |
Kirby, MK | 1 |
Ramaker, RC | 1 |
Roberts, BS | 1 |
Lasseigne, BN | 1 |
Gunther, DS | 1 |
Burwell, TC | 1 |
Davis, NS | 1 |
Gulzar, ZG | 1 |
Absher, DM | 1 |
Cooper, SJ | 1 |
Brooks, JD | 1 |
Myers, RM | 1 |
Pistore, C | 1 |
Giannoni, E | 1 |
Colangelo, T | 1 |
Rizzo, F | 1 |
Magnani, E | 1 |
Muccillo, L | 1 |
Giurato, G | 1 |
Mancini, M | 1 |
Rizzo, S | 1 |
Riccardi, M | 1 |
Sahnane, N | 1 |
Del Vescovo, V | 1 |
Kishore, K | 1 |
Mandruzzato, M | 1 |
Macchi, F | 1 |
Pelizzola, M | 1 |
Denti, MA | 1 |
Furlan, D | 1 |
Weisz, A | 1 |
Colantuoni, V | 1 |
Chiarugi, P | 1 |
Bonapace, IM | 1 |
Storebjerg, TM | 1 |
Strand, SH | 1 |
Høyer, S | 1 |
Lynnerup, AS | 1 |
Borre, M | 1 |
Ørntoft, TF | 1 |
Sørensen, KD | 1 |
Takayama, K | 1 |
Misawa, A | 1 |
Suzuki, T | 1 |
Takagi, K | 1 |
Hayashizaki, Y | 1 |
Fujimura, T | 1 |
Homma, Y | 1 |
Takahashi, S | 1 |
Urano, T | 1 |
Inoue, S | 1 |
Haffner, MC | 1 |
Chaux, A | 1 |
Meeker, AK | 1 |
Esopi, DM | 1 |
Gerber, J | 1 |
Pellakuru, LG | 1 |
Toubaji, A | 1 |
Argani, P | 1 |
Iacobuzio-Donahue, C | 1 |
Nelson, WG | 1 |
Netto, GJ | 1 |
De Marzo, AM | 1 |
Yegnasubramanian, S | 1 |
Cortese, R | 1 |
Kwan, A | 1 |
Lalonde, E | 1 |
Bryzgunova, O | 1 |
Bondar, A | 1 |
Wu, Y | 1 |
Gordevicius, J | 1 |
Park, M | 1 |
Oh, G | 1 |
Kaminsky, Z | 1 |
Tverkuviene, J | 1 |
Laurinavicius, A | 1 |
Jankevicius, F | 1 |
Sendorek, DH | 1 |
Haider, S | 1 |
Wang, SC | 1 |
Jarmalaite, S | 1 |
Laktionov, P | 1 |
Boutros, PC | 1 |
Petronis, A | 1 |
Jacob, ST | 1 |
Majumder, S | 1 |
Ghoshal, K | 1 |
Pakneshan, P | 1 |
Xing, RH | 1 |
Rabbani, SA | 2 |
Lin, CC | 1 |
Wu, HC | 1 |
Tsai, FJ | 1 |
Chen, HY | 1 |
Chen, WC | 1 |
Trzeciak, AR | 1 |
Nyaga, SG | 1 |
Jaruga, P | 1 |
Lohani, A | 1 |
Dizdaroglu, M | 1 |
Evans, MK | 1 |
Powell, IJ | 1 |
Land, SJ | 1 |
Dey, J | 1 |
Heilbrun, LK | 1 |
Hughes, MR | 1 |
Sakr, W | 1 |
Everson, RB | 1 |
Hoffman, RM | 1 |
Grove, KL | 2 |
Guo, X | 1 |
Liu, SH | 1 |
Gao, Z | 1 |
Chu, CK | 1 |
Cheng, YC | 2 |
Sarosdy, MF | 2 |
Higdon, AL | 1 |
Demoor, CA | 1 |
Lievano, G | 1 |
Di Domenico, D | 1 |
Brown, J | 1 |
Bridges, P | 1 |
Rubenstein, M | 2 |
Shaw, M | 2 |
Guinan, P | 2 |
Akaza, H | 1 |
Ratanawong, S | 1 |
Chou, P | 1 |
Ray, V | 1 |
Mirochnik, Y | 1 |
Slobodskoy, L | 1 |
Harakidas, P | 1 |
Bowlin, T | 1 |
Attardo, G | 1 |
Steiner, M | 1 |
Hillenbrand, M | 1 |
Borkowsi, M | 1 |
Seiter, H | 1 |
Schuff-Werner, P | 1 |
Tamada, H | 1 |
Kitazawa, R | 1 |
Gohji, K | 1 |
Kitazawa, S | 1 |
Singal, R | 1 |
van Wert, J | 1 |
Bashambu, M | 1 |
Gourdeau, H | 1 |
Clarke, ML | 1 |
Ouellet, F | 1 |
Mowles, D | 1 |
Selner, M | 1 |
Richard, A | 1 |
Lee, N | 1 |
Mackey, JR | 1 |
Young, JD | 1 |
Jolivet, J | 1 |
Lafrenière, RG | 1 |
Cass, CE | 1 |
Gilbert, SM | 1 |
Benson, MC | 1 |
McKiernan, JM | 1 |
Gelmann, EP | 1 |
Bedford, MT | 1 |
van Helden, PD | 1 |
3 reviews available for cytosine and Cancer of Prostate
Article | Year |
---|---|
[Development of new drugs for urological cancers].
Topics: Androgen Antagonists; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Carcinoma, Renal Cell; | 1997 |
Linkage disequilibrium between the androgen receptor gene CAG and GGC repeats in the African-American population.
Topics: Adenine; Black People; Cytosine; Guanosine; Humans; Linkage Disequilibrium; Male; Prostatic Neoplasm | 2002 |
Molecular biology of the androgen receptor.
Topics: Adenine; Animals; Cytosine; Guanine; Humans; Male; Prostatic Neoplasms; Receptors, Androgen; Risk; T | 2002 |
25 other studies available for cytosine and Cancer of Prostate
Article | Year |
---|---|
The CAG-triplet in the androgen receptor gene and single-nucleotide polymorphisms in androgen pathway genes in patients with concomitant bladder and prostate cancer.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Adenine; Androgens; Cytosine; Guanine; Humans; Male; Membrane | 2022 |
Genome-wide DNA methylation measurements in prostate tissues uncovers novel prostate cancer diagnostic biomarkers and transcription factor binding patterns.
Topics: Adult; Aged; Biomarkers, Tumor; Cytosine; DNA Methylation; Enhancer of Zeste Homolog 2 Protein; Huma | 2017 |
DNA methylation variations are required for epithelial-to-mesenchymal transition induced by cancer-associated fibroblasts in prostate cancer cells.
Topics: Cancer-Associated Fibroblasts; Cell Line, Tumor; Cell Transformation, Neoplastic; Culture Media, Con | 2017 |
Dysregulation and prognostic potential of 5-methylcytosine (5mC), 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and 5-carboxylcytosine (5caC) levels in prostate cancer.
Topics: 5-Methylcytosine; Adult; Aged; Cytosine; DNA Methylation; Epigenesis, Genetic; Gene Expression Regul | 2018 |
TET2 repression by androgen hormone regulates global hydroxymethylation status and prostate cancer progression.
Topics: 5-Methylcytosine; Aged; Androgens; Animals; Blotting, Western; Cell Line, Tumor; Cell Proliferation; | 2015 |
Global 5-hydroxymethylcytosine content is significantly reduced in tissue stem/progenitor cell compartments and in human cancers.
Topics: 5-Methylcytosine; Adenocarcinoma; Animals; Breast Neoplasms; Carcinoma, Ductal, Breast; Cell Differe | 2011 |
Epigenetic markers of prostate cancer in plasma circulating DNA.
Topics: Aged; Biomarkers, Tumor; Case-Control Studies; Centromere; Chromosomes, Human, Pair 10; Cytosine; DN | 2012 |
Suppression of metallothionein-I/II expression and its probable molecular mechanisms.
Topics: Animals; Carcinoma, Hepatocellular; CCAAT-Enhancer-Binding Proteins; Cytosine; DNA-Binding Proteins; | 2002 |
Methylation status of uPA promoter as a molecular mechanism regulating prostate cancer invasion and growth in vitro and in vivo.
Topics: Animals; Base Sequence; Blotting, Southern; Cell Division; Cytosine; DNA Methylation; Gene Expressio | 2003 |
Vascular endothelial growth factor gene-460 C/T polymorphism is a biomarker for prostate cancer.
Topics: Aged; Aged, 80 and over; Biomarkers, Tumor; Cytosine; Endothelial Growth Factors; Genetic Markers; H | 2003 |
Cellular repair of oxidatively induced DNA base lesions is defective in prostate cancer cell lines, PC-3 and DU-145.
Topics: Adenine; Antioxidants; Blotting, Western; Catalase; Cell Division; Cell Line, Tumor; Cell Nucleus; C | 2004 |
The impact of CAG repeats in exon 1 of the androgen receptor on disease progression after prostatectomy.
Topics: Adenine; Age Factors; Aged; Black People; Cytosine; Disease Progression; Exons; Genotype; Guanine; H | 2005 |
Orthotopic metastatic (MetaMouse) models for discovery and development of novel chemotherapy.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Camptothecin; Cisplatin; Colonic Neoplasms; | 2005 |
Anticancer activity of beta-L-dioxolane-cytidine, a novel nucleoside analogue with the unnatural L configuration.
Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Division; Colonic Neoplasms; Cytarab | 1995 |
In vivo antitumor activity of bropirimine against PAIII and Dunning MAT-LyLu rodent prostate cancers.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cytosine; Male; Neoplasm Transplantation; Prostatic | 1996 |
Uptake and metabolism of the new anticancer compound beta-L-(-)-dioxolane-cytidine in human prostate carcinoma DU-145 cells.
Topics: Antimetabolites, Antineoplastic; Biological Transport; Cell Line; Cytarabine; Cytosine; Dioxolanes; | 1996 |
Oral bropirimine immunotherapy of rodent prostate cancer.
Topics: Adjuvants, Immunologic; Administration, Oral; Animals; Antineoplastic Agents; Cell Division; Cytosin | 1997 |
Bropirimine as neoadjuvant therapy decreases residual disease and expression of markers PCNA and TGF-beta 1 in a rat orthotopic prostate adenocarcinoma.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Biomarkers, Tumor; Cytosine; Down-Regulation; Gene E | 1997 |
Paclitaxel, bropirimine and linomide: effect on growth inhibition in a murine prostate cancer model by different growth regulatory mechanisms.
Topics: Animals; Antineoplastic Agents; Cell Division; Cytosine; Hydroxyquinolines; Immunohistochemistry; Ma | 1998 |
Effect of nucleoside analogue BCH-4556 on prostate cancer growth and metastases in vitro and in vivo.
Topics: Animals; Antineoplastic Agents; Bone Neoplasms; Cell Division; Cytosine; Dioxolanes; Doxorubicin; Ma | 1998 |
609 C --> T polymorphism in NAD(P)H:quinone oxidoreductase gene in patients with prostatic adenocarcinoma or benign prostatic hyperplasia.
Topics: Adenocarcinoma; Alleles; Cytosine; Female; Genes, Neoplasm; Genotype; Humans; Male; NAD(P)H Dehydrog | 1999 |
Epigenetic regulation of human bone morphogenetic protein 6 gene expression in prostate cancer.
Topics: Aged; Blotting, Northern; Bone Morphogenetic Protein 2; Bone Morphogenetic Protein 6; Bone Morphogen | 2001 |
Cytosine methylation represses glutathione S-transferase P1 (GSTP1) gene expression in human prostate cancer cells.
Topics: Azacitidine; Base Sequence; Cytosine; Decitabine; DNA Methylation; Enzyme Inhibitors; Gene Expressio | 2001 |
Mechanisms of uptake and resistance to troxacitabine, a novel deoxycytidine nucleoside analogue, in human leukemic and solid tumor cell lines.
Topics: Amino Acid Sequence; Antineoplastic Agents; Biological Transport; Carrier Proteins; Cytarabine; Cyti | 2001 |
Hypomethylation of DNA in pathological conditions of the human prostate.
Topics: 5-Methylcytosine; Adult; Aged; Aged, 80 and over; Cytosine; DNA; Humans; Male; Mathematics; Methylat | 1987 |