cytosine has been researched along with Cancer of Lung in 50 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report the history of an 8-year-old girl who was treated for suspected lung lesions of respiratory papillomatosis with Indole-3-Carbinol, local and intravenous injections of Cidofovir for 27 months." | 7.73 | Successful use of intralesional and intravenous cidofovir in association with indole-3-carbinol in an 8-year-old girl with pulmonary papillomatosis. ( Bodart, E; de Bilderling, G; De Clercq, E; Lawson, G; Naesens, L; Remacle, M; Snoeck, R; Tuerlinckx, D, 2005) |
| "We report the history of an 8-year-old girl who was treated for suspected lung lesions of respiratory papillomatosis with Indole-3-Carbinol, local and intravenous injections of Cidofovir for 27 months." | 3.73 | Successful use of intralesional and intravenous cidofovir in association with indole-3-carbinol in an 8-year-old girl with pulmonary papillomatosis. ( Bodart, E; de Bilderling, G; De Clercq, E; Lawson, G; Naesens, L; Remacle, M; Snoeck, R; Tuerlinckx, D, 2005) |
| " In both human lung adenocarcinoma cells (HTB-54) and human rhabdomyosarcoma cells (CCl-136), pulse exposures to the topoisomerase II inhibitors etoposide and nalidixic acid; to the antibiotic doxorubicin; to the microtubule inhibitors vincristine, vinblastine, and colchicine; to the DNA cross-linking agent cisplatinum; to hydroxyurea; and to the antimetabolites 1-beta-D-arabinofuranosylcytosine, 5-fluorouracil, 5-fluorodeoxyuridine, and methotrexate were associated with profound drug-induced DNA hypermethylation." | 3.67 | Drug-induced DNA hypermethylation and drug resistance in human tumors. ( Nyce, J, 1989) |
| " Pyrimidinone compounds 2-amino-5-bromo-6-methyl-4-pyrimidinone (ABMP), 2-amino-5-brome-6-phenyl-4-pyrimidinone (ABPP), and 2-amino-5-iodo-6-phenyl-4-pyrimidinone (AIPP) were studied for their activities against artificial lung metastases of the weakly immunogenic spontaneous fibrosarcoma NFSa, the moderately immunogenic spontaneous mammary carcinoma MCa-K, and the strongly immunogenic 3-methylcholanthrene-induced fibrosarcoma FSa syngeneic to inbred C3Hf/Kam mice." | 3.66 | Studies on the antitumor activities of pyrimidinone-interferon inducers. I. Effect against artificial and spontaneous lung metastases of murine tumors. ( Hersh, EM; Hunter, N; Milas, L; Stringfellow, DA, 1982) |
| " In a 3 + 3 dose-escalation design, the dosage levels for CpG ODN (K3) were 5 or 10 mg/body via subcutaneous injection and 0." | 3.11 | CpG ODN (K3)-toll-like receptor 9 agonist-induces Th1-type immune response and enhances cytotoxic activity in advanced lung cancer patients: a phase I study. ( Hamaguchi, M; Hirata, H; Ishii, KJ; Kida, H; Kimura, K; Kumanogoh, A; Kuroda, E; Manabe, Y; Miyake, K; Mizuno, Y; Nishida, S; Otsuka, T; Shibahara, T; Shiroyama, T; Takeda, Y; Temizoz, B; Yagita, M, 2022) |
| "In squamous cell lung cancers, levels of 5hmdC were depleted substantially with up to 5-fold reduction compared with normal lung tissue." | 1.37 | 5-Hydroxymethylcytosine is strongly depleted in human cancers but its levels do not correlate with IDH1 mutations. ( Jiang, Y; Jin, SG; Krex, D; Lu, Q; Pfeifer, GP; Qiu, R; Rauch, TA; Schackert, G; Wang, Y, 2011) |
| "By comparing the metabolism in mouse lymphosarcoma S49-wild type (S49-WT) and mutant cells deficient for dCMP deaminase, we identified the mono- and diphosphate metabolites generated from HPMP-5-azaC and its deaminated product HPMP-5-azaU." | 1.35 | Intracellular metabolism of the new antiviral compound 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]-5-azacytosine. ( Andrei, G; De Clercq, E; Holý, A; Krecmerová, M; Naesens, L; Neyts, J; Snoeck, R; Votruba, I, 2008) |
| "With these fluorescent tools, tumors and metastasis in host organs can be externally imaged down to the single-cell level." | 1.33 | Orthotopic metastatic (MetaMouse) models for discovery and development of novel chemotherapy. ( Hoffman, RM, 2005) |
| "Second, tumors occurring in homozygous carriers of the methionine synthase 2756G allele show a lower number of hypermethylated CpG islands of tumor suppressor genes (P = 0." | 1.31 | Germ-line variants in methyl-group metabolism genes and susceptibility to DNA methylation in normal tissues and human primary tumors. ( Avila, S; Capella, G; Esteller, M; Fraga, MF; Herman, JG; Paz, MF; Peinado, MA; Pollan, M; Sanchez-Cespedes, M, 2002) |
| "All lung cancers were hyperploid." | 1.27 | Biochemical and cytogenetic studies of human lung cancers. ( Bates, SE; Benfield, JR; Derrick, M; Hammond, WG; Ohnuki, Y; Shively, J; Smith, SS; Teplitz, RL; Wain, JC, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (10.00) | 18.7374 |
| 1990's | 10 (20.00) | 18.2507 |
| 2000's | 25 (50.00) | 29.6817 |
| 2010's | 7 (14.00) | 24.3611 |
| 2020's | 3 (6.00) | 2.80 |
| Authors | Studies |
|---|---|
| Otsuka, T | 1 |
| Nishida, S | 1 |
| Shibahara, T | 1 |
| Temizoz, B | 1 |
| Hamaguchi, M | 1 |
| Shiroyama, T | 1 |
| Kimura, K | 1 |
| Miyake, K | 1 |
| Hirata, H | 1 |
| Mizuno, Y | 1 |
| Yagita, M | 1 |
| Manabe, Y | 1 |
| Kuroda, E | 1 |
| Takeda, Y | 1 |
| Kida, H | 1 |
| Ishii, KJ | 1 |
| Kumanogoh, A | 1 |
| Heryanto, YD | 1 |
| Katayama, K | 1 |
| Imoto, S | 1 |
| Seiler, CL | 1 |
| Song, JUM | 1 |
| Kotandeniya, D | 1 |
| Chen, J | 1 |
| Kono, TJY | 1 |
| Han, Q | 1 |
| Colwell, M | 1 |
| Auch, B | 1 |
| Sarver, AL | 1 |
| Upadhyaya, P | 1 |
| Ren, Y | 1 |
| Faulk, C | 1 |
| De Flora, S | 1 |
| La Maestra, S | 1 |
| Chen, Y | 1 |
| Kassie, F | 1 |
| Tretyakova, NY | 1 |
| Tessema, M | 1 |
| Yingling, CM | 1 |
| Snider, AM | 1 |
| Do, K | 1 |
| Juri, DE | 1 |
| Picchi, MA | 1 |
| Zhang, X | 1 |
| Liu, Y | 1 |
| Leng, S | 1 |
| Tellez, CS | 1 |
| Belinsky, SA | 2 |
| Liekens, S | 1 |
| Noppen, S | 1 |
| Gijsbers, S | 1 |
| Sienaert, R | 1 |
| Ronca, R | 1 |
| Tobia, C | 1 |
| Presta, M | 1 |
| Maeda, K | 1 |
| Yasui, H | 1 |
| Yamamori, T | 1 |
| Matsuura, T | 1 |
| Takao, S | 1 |
| Suzuki, M | 1 |
| Matsuda, A | 1 |
| Inanami, O | 1 |
| Shirato, H | 1 |
| Ouchi, M | 1 |
| Kawamura, H | 1 |
| Urata, Y | 1 |
| Fujiwara, T | 1 |
| Naesens, L | 2 |
| Andrei, G | 1 |
| Votruba, I | 1 |
| Krecmerová, M | 1 |
| Holý, A | 1 |
| Neyts, J | 1 |
| De Clercq, E | 2 |
| Snoeck, R | 2 |
| Lam, W | 1 |
| Bussom, S | 1 |
| Cheng, YC | 1 |
| Mitsui, M | 1 |
| Nishikawa, M | 1 |
| Zang, L | 1 |
| Ando, M | 1 |
| Hattori, K | 1 |
| Takahashi, Y | 1 |
| Watanabe, Y | 1 |
| Takakura, Y | 1 |
| Christensen, BC | 1 |
| Marsit, CJ | 1 |
| Houseman, EA | 1 |
| Godleski, JJ | 1 |
| Longacker, JL | 1 |
| Zheng, S | 1 |
| Yeh, RF | 1 |
| Wrensch, MR | 1 |
| Wiemels, JL | 1 |
| Karagas, MR | 1 |
| Bueno, R | 1 |
| Sugarbaker, DJ | 1 |
| Nelson, HH | 1 |
| Wiencke, JK | 1 |
| Kelsey, KT | 1 |
| Mercier, C | 1 |
| Dahan, L | 1 |
| Ouafik, L | 1 |
| André, N | 1 |
| Ciccolini, J | 1 |
| Zheng, X | 1 |
| Duan, W | 1 |
| Xu, J | 1 |
| Nie, C | 1 |
| Yang, Z | 1 |
| Wang, H | 1 |
| Wang, W | 1 |
| Lu, D | 1 |
| Jin, SG | 1 |
| Jiang, Y | 1 |
| Qiu, R | 1 |
| Rauch, TA | 1 |
| Wang, Y | 1 |
| Schackert, G | 1 |
| Krex, D | 1 |
| Lu, Q | 1 |
| Pfeifer, GP | 5 |
| Choi, WJ | 1 |
| Chung, HJ | 1 |
| Chandra, G | 1 |
| Alexander, V | 1 |
| Zhao, LX | 1 |
| Lee, HW | 1 |
| Nayak, A | 1 |
| Majik, MS | 1 |
| Kim, HO | 1 |
| Kim, JH | 1 |
| Lee, YB | 1 |
| Ahn, CH | 1 |
| Lee, SK | 1 |
| Jeong, LS | 1 |
| Paz, MF | 1 |
| Avila, S | 1 |
| Fraga, MF | 1 |
| Pollan, M | 1 |
| Capella, G | 1 |
| Peinado, MA | 1 |
| Sanchez-Cespedes, M | 1 |
| Herman, JG | 3 |
| Esteller, M | 1 |
| Speina, E | 1 |
| Zielińska, M | 1 |
| Barbin, A | 1 |
| Gackowski, D | 1 |
| Kowalewski, J | 1 |
| Graziewicz, MA | 1 |
| Siedlecki, JA | 1 |
| Oliński, R | 1 |
| Tudek, B | 1 |
| Klinge, DM | 1 |
| Stidley, CA | 1 |
| Issa, JP | 1 |
| March, TH | 1 |
| Baylin, SB | 3 |
| Boivin, AJ | 1 |
| Gourdeau, H | 1 |
| Momparler, RL | 1 |
| de Bilderling, G | 1 |
| Bodart, E | 1 |
| Lawson, G | 1 |
| Tuerlinckx, D | 1 |
| Remacle, M | 1 |
| Hoffman, RM | 1 |
| Kouidou, S | 1 |
| Agidou, T | 1 |
| Kyrkou, A | 1 |
| Andreou, A | 1 |
| Katopodi, T | 1 |
| Georgiou, E | 1 |
| Krikelis, D | 1 |
| Dimitriadou, A | 1 |
| Spanos, P | 1 |
| Tsilikas, C | 1 |
| Destouni, H | 1 |
| Tzimagiorgis, G | 1 |
| Seymour, CW | 1 |
| Krimsky, WS | 1 |
| Sager, J | 1 |
| Kruklitis, RJ | 1 |
| Lund, ME | 1 |
| Musani, AI | 1 |
| Sterman, DH | 1 |
| Gekeler, V | 1 |
| Gimmnich, P | 1 |
| Hofmann, HP | 1 |
| Grebe, C | 1 |
| Römmele, M | 1 |
| Leja, A | 1 |
| Baudler, M | 1 |
| Benimetskaya, L | 1 |
| Gonser, B | 1 |
| Pieles, U | 1 |
| Maier, T | 1 |
| Wagner, T | 1 |
| Sanders, K | 1 |
| Beck, JF | 1 |
| Hanauer, G | 1 |
| Stein, CA | 1 |
| Galmarini, CM | 1 |
| Gilbert, J | 1 |
| Carducci, MA | 1 |
| Baker, SD | 1 |
| Dees, EC | 1 |
| Donehower, R | 1 |
| Ehrich, M | 1 |
| Field, JK | 1 |
| Liloglou, T | 1 |
| Xinarianos, G | 1 |
| Oeth, P | 1 |
| Nelson, MR | 1 |
| Cantor, CR | 1 |
| van den Boom, D | 1 |
| Radi, M | 1 |
| Adema, AD | 1 |
| Daft, JR | 1 |
| Cho, JH | 1 |
| Hoebe, EK | 1 |
| Alexander, LE | 1 |
| Peters, GJ | 1 |
| Chu, CK | 1 |
| Milas, L | 1 |
| Hersh, EM | 1 |
| Stringfellow, DA | 1 |
| Hunter, N | 1 |
| Ganderton, RH | 1 |
| Day, IN | 1 |
| Briggs, RS | 1 |
| Merlo, A | 1 |
| Mao, L | 1 |
| Lee, DJ | 1 |
| Gabrielson, E | 1 |
| Burger, PC | 1 |
| Sidransky, D | 1 |
| Vertino, PM | 1 |
| Spillare, EA | 1 |
| Harris, CC | 1 |
| Gordon, YJ | 1 |
| Araullo-Cruz, TP | 1 |
| Johnson, YF | 1 |
| Romanowski, EG | 1 |
| Kinchington, PR | 1 |
| Mass, MJ | 1 |
| Wang, L | 1 |
| Guang, SG | 1 |
| Ogura, T | 1 |
| Sekine, I | 1 |
| Yokozaki, M | 1 |
| Esumi, H | 1 |
| Kodama, T | 1 |
| Nagai, K | 1 |
| Denissenko, MF | 2 |
| Chen, H | 1 |
| Lum, A | 1 |
| Seifried, A | 1 |
| Wilkens, LR | 1 |
| Le Marchand, L | 1 |
| Tang, M | 1 |
| Dammann, R | 1 |
| Li, C | 1 |
| Yoon, JH | 1 |
| Chin, PL | 1 |
| Bates, S | 1 |
| Piyathilake, CJ | 2 |
| Johanning, GL | 2 |
| Frost, AR | 2 |
| Whiteside, MA | 1 |
| Manne, U | 1 |
| Grizzle, WE | 2 |
| Heimburger, DC | 2 |
| Niveleau, A | 2 |
| Armbruster, C | 2 |
| Kreuzer, A | 1 |
| Vorbach, H | 1 |
| Huber, M | 1 |
| Bell, WC | 1 |
| Oelschlager, D | 1 |
| Weiss, H | 1 |
| Auborn, KJ | 1 |
| Top, B | 1 |
| Kliasheva, RI | 1 |
| Nyce, J | 1 |
| Benfield, JR | 1 |
| Wain, JC | 1 |
| Derrick, M | 1 |
| Smith, SS | 1 |
| Ohnuki, Y | 1 |
| Bates, SE | 1 |
| Shively, J | 1 |
| Teplitz, RL | 1 |
| Hammond, WG | 1 |
| Eggermont, AM | 2 |
| Sugarbaker, PH | 1 |
| Marquet, RL | 2 |
| Jeekel, J | 2 |
| De Bruin, RW | 1 |
| Weimar, W | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy and Safety Assessment of Oral LBH589 in Adult Patients With Advanced Soft Tissue Sarcoma After Pre-treatment Failure: an Open-label, Multicenter Phase II Study[NCT01136499] | Phase 2 | 53 participants (Actual) | Interventional | 2010-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for cytosine and Cancer of Lung
| Article | Year |
|---|---|
Transbronchial needle injection: a systematic review of a new diagnostic and therapeutic paradigm.
Topics: Bronchoscopy; Catheterization; Cidofovir; Cytosine; Equipment Design; Humans; Injections; Lung Disea | 2006 |
Formation and repair of DNA lesions in the p53 gene: relation to cancer mutations?
Topics: 5-Methylcytosine; Animals; Benzo(a)pyrene; Breast Neoplasms; Carcinogens, Environmental; Colonic Neo | 1998 |
Mutation hotspots and DNA methylation.
Topics: 5-Methylcytosine; Carcinogens; CpG Islands; Cytosine; DNA Methylation; Genes, p53; Genes, Tumor Supp | 2000 |
p53 mutational spectra and the role of methylated CpG sequences.
Topics: 5-Methylcytosine; Carcinogens; CpG Islands; Cytosine; DNA Methylation; DNA Repair; DNA, Neoplasm; Ge | 2000 |
Therapy for recurrent respiratory papillomatosis.
Topics: Cidofovir; Cytosine; Humans; Interferons; Laryngeal Neoplasms; Lung Neoplasms; Neoplasm Recurrence, | 2002 |
2 trials available for cytosine and Cancer of Lung
| Article | Year |
|---|---|
CpG ODN (K3)-toll-like receptor 9 agonist-induces Th1-type immune response and enhances cytotoxic activity in advanced lung cancer patients: a phase I study.
Topics: Adaptive Immunity; Adjuvants, Immunologic; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; CD | 2022 |
A Phase I study of the oral antimetabolite, CS-682, administered once daily 5 days per week in patients with refractory solid tumor malignancies.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Arabinonucleo | 2006 |
43 other studies available for cytosine and Cancer of Lung
| Article | Year |
|---|---|
Analyzing integrated network of methylation and gene expression profiles in lung squamous cell carcinoma.
Topics: Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Chromosomal Proteins, N | 2022 |
Inhalation exposure to cigarette smoke and inflammatory agents induces epigenetic changes in the lung.
Topics: Animals; Carcinogens; Cell Proliferation; Chromatography, High Pressure Liquid; CpG Islands; Cytosin | 2020 |
GATA2 is epigenetically repressed in human and mouse lung tumors and is not requisite for survival of KRAS mutant lung cancer.
Topics: Animals; Carcinoma, Non-Small-Cell Lung; Cell Death; Cell Line, Tumor; Cell Survival; Cell Transform | 2014 |
The broad-spectrum anti-DNA virus agent cidofovir inhibits lung metastasis of virus-independent, FGF2-driven tumors.
Topics: Animals; Antiviral Agents; Apoptosis; Blotting, Western; Cell Proliferation; Cidofovir; Cytosine; Em | 2015 |
A Nucleoside Anticancer Drug, 1-(3-C-Ethynyl-β-D-Ribo-Pentofuranosyl)Cytosine, Induces Depth-Dependent Enhancement of Tumor Cell Death in Spread-Out Bragg Peak (SOBP) of Proton Beam.
Topics: A549 Cells; Animals; Antineoplastic Agents; Cell Death; Cricetinae; Cricetulus; Cytosine; DNA Breaks | 2016 |
Antiviral activity of cidofovir against telomerase-specific replication-selective oncolytic adenovirus, OBP-301 (Telomelysin).
Topics: Adenoviridae; Antiviral Agents; Cell Line, Tumor; Cidofovir; Cytopathogenic Effect, Viral; Cytosine; | 2009 |
Intracellular metabolism of the new antiviral compound 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]-5-azacytosine.
Topics: Animals; Antiviral Agents; Cell Line, Tumor; Cidofovir; Cytosine; DNA Replication; DNA Viruses; DNA, | 2008 |
Effect of hypoxia on the expression of phosphoglycerate kinase and antitumor activity of troxacitabine and gemcitabine in non-small cell lung carcinoma.
Topics: Animals; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Death; Cell Hypoxia; Cell Line, | 2009 |
Effect of the content of unmethylated CpG dinucleotides in plasmid DNA on the sustainability of transgene expression.
Topics: Animals; Cell Line, Tumor; CpG Islands; Cytokines; Cytosine; Dinucleoside Phosphates; DNA; DNA Methy | 2009 |
Differentiation of lung adenocarcinoma, pleural mesothelioma, and nonmalignant pulmonary tissues using DNA methylation profiles.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; CpG Islands; Cytosine; Diagnosis, Differential; DNA | 2009 |
Letter to the editor: pharmacokinetics of gemcitabine in non-small-cell lung cancer patients: impact of the 79A>C cytidine deaminase polymorphism.
Topics: Adenine; Antimetabolites, Antineoplastic; Carcinoma, Non-Small-Cell Lung; Confounding Factors, Epide | 2010 |
Functionally significant nicotine acetylcholine receptor subunit α5 promoter haplotypes are associated with susceptibility to lung cancer in Chinese.
Topics: Adult; Aged; Asian People; Case-Control Studies; China; Cytosine; Female; Gene Deletion; Gene Freque | 2011 |
5-Hydroxymethylcytosine is strongly depleted in human cancers but its levels do not correlate with IDH1 mutations.
Topics: 5-Methylcytosine; Animals; Base Sequence; Brain; Brain Neoplasms; Carcinoma, Squamous Cell; Cell Lin | 2011 |
Fluorocyclopentenyl-cytosine with broad spectrum and potent antitumor activity.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Cyclopentanes; Cytosine; Humans; Lu | 2012 |
Germ-line variants in methyl-group metabolism genes and susceptibility to DNA methylation in normal tissues and human primary tumors.
Topics: 5-Methylcytosine; 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adenocarcinoma; Breast | 2002 |
Decreased repair activities of 1,N(6)-ethenoadenine and 3,N(4)-ethenocytosine in lung adenocarcinoma patients.
Topics: Adenine; Adenocarcinoma; Adult; Age Factors; Aged; Cytosine; DNA Adducts; DNA Repair; DNA, Neoplasm; | 2003 |
Inhibition of DNA methylation and histone deacetylation prevents murine lung cancer.
Topics: Alleles; Animals; Antimetabolites, Antineoplastic; Azacitidine; Cytosine; Decitabine; DNA (Cytosine- | 2003 |
Action of troxacitabine on cells transduced with human cytidine deaminase cDNA.
Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cytarabine; Cytidine Deaminase; Cytosine; Dio | 2004 |
Successful use of intralesional and intravenous cidofovir in association with indole-3-carbinol in an 8-year-old girl with pulmonary papillomatosis.
Topics: Antiviral Agents; Chemotherapy, Adjuvant; Child; Cidofovir; Cytosine; Drug Therapy, Combination; Fem | 2005 |
Orthotopic metastatic (MetaMouse) models for discovery and development of novel chemotherapy.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Camptothecin; Cisplatin; Colonic Neoplasms; | 2005 |
Non-CpG cytosine methylation of p53 exon 5 in non-small cell lung carcinoma.
Topics: Base Sequence; Carcinoma, Non-Small-Cell Lung; CpG Islands; Cytosine; Databases, Genetic; DNA Methyl | 2005 |
G3139 and other CpG-containing immunostimulatory phosphorothioate oligodeoxynucleotides are potent suppressors of the growth of human tumor xenografts in nude mice.
Topics: Adenocarcinoma; Adjuvants, Immunologic; Animals; Antineoplastic Agents; B-Lymphocytes; Carcinoma; Ce | 2006 |
Drug evaluation: sapacitabine--an orally available antimetabolite in the treatment of cancer.
Topics: Administration, Oral; Animals; Antimetabolites, Antineoplastic; Arabinonucleosides; Carcinoma, Non-S | 2006 |
Cytosine methylation profiles as a molecular marker in non-small cell lung cancer.
Topics: Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; Cluster Analysis; CpG Islands; Cytosine; DNA Meth | 2006 |
In vitro optimization of non-small cell lung cancer activity with troxacitabine, L-1,3-dioxolane-cytidine, prodrugs.
Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cytosine; Dioxolanes; Drug | 2007 |
Studies on the antitumor activities of pyrimidinone-interferon inducers. I. Effect against artificial and spontaneous lung metastases of murine tumors.
Topics: Animals; Cytosine; Dose-Response Relationship, Drug; Fibrosarcoma; Immunity, Innate; Interferon Indu | 1982 |
Patterns of DNA methylation of the parathyroid hormone-related protein gene in human lung carcinoma.
Topics: 5-Methylcytosine; Cytosine; DNA, Neoplasm; Electrophoresis, Agar Gel; Humans; Lung; Lung Neoplasms; | 1995 |
5' CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers.
Topics: 5-Methylcytosine; Alleles; Azacitidine; Base Sequence; Brain Neoplasms; Carcinoma, Non-Small-Cell Lu | 1995 |
Altered chromosomal methylation patterns accompany oncogene-induced transformation of human bronchial epithelial cells.
Topics: Base Sequence; Bronchi; Calcitonin; Cell Transformation, Neoplastic; Chromosomes, Human, Pair 11; Ch | 1993 |
Isolation of human adenovirus type 5 variants resistant to the antiviral cidofovir.
Topics: Adenoviruses, Human; Antiviral Agents; Cidofovir; Cytopathogenic Effect, Viral; Cytosine; Drug Resis | 1996 |
Arsenic alters cytosine methylation patterns of the promoter of the tumor suppressor gene p53 in human lung cells: a model for a mechanism of carcinogenesis.
Topics: Adenocarcinoma; Arsenic; Base Sequence; Carcinogens; Cytosine; DNA Methylation; Gene Expression Regu | 1997 |
Association between p53 mutation and clinicopathological features of non-small cell lung cancer.
Topics: Adenocarcinoma; Adenocarcinoma, Papillary; Adult; Aged; Aged, 80 and over; Analysis of Variance; Bas | 1997 |
Association of the NAD(P)H:quinone oxidoreductase 609C-->T polymorphism with a decreased lung cancer risk.
Topics: Alleles; Asian People; Case-Control Studies; Cytosine; Female; Genetic Variation; Genotype; Hawaii; | 1999 |
Epigenetic inactivation of a RAS association domain family protein from the lung tumour suppressor locus 3p21.3.
Topics: 5-Methylcytosine; Alternative Splicing; Amino Acid Sequence; Animals; Base Sequence; Carcinoma, Non- | 2000 |
Immunohistochemical evaluation of global DNA methylation: comparison with in vitro radiolabeled methyl incorporation assay.
Topics: 5-Methylcytosine; Biological Assay; Carcinoma, Squamous Cell; Cytosine; DNA Methylation; DNA, Neopla | 2000 |
Successful treatment of severe respiratory papillomatosis with intravenous cidofovir and interferon alpha-2b.
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cidofovir; Cytosine; F | 2001 |
Altered global methylation of DNA: an epigenetic difference in susceptibility for lung cancer is associated with its progression.
Topics: 5-Methylcytosine; Antibodies, Monoclonal; Bronchi; Carcinoma, Squamous Cell; Cytosine; Disease Progr | 2001 |
A simple method to attach a universal 50-bp GC-clamp to PCR fragments used for mutation analysis by DGGE.
Topics: Base Composition; Base Sequence; Carcinoma, Non-Small-Cell Lung; Cytosine; DNA Mutational Analysis; | 1992 |
[DNA methylation in human lung tumors].
Topics: Chromatography, Thin Layer; Cytosine; DNA; DNA, Neoplasm; Electrophoresis, Agar Gel; Humans; In Vitr | 1990 |
Drug-induced DNA hypermethylation and drug resistance in human tumors.
Topics: 5-Methylcytosine; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Line; Cell Survival; Cytosin | 1989 |
Biochemical and cytogenetic studies of human lung cancers.
Topics: Animals; Cytosine; DNA, Neoplasm; Electrophoresis, Agar Gel; Female; Humans; Karyotyping; Lung Neopl | 1988 |
Synergistic antitumor activity of cyclophosphamide and ABPP in the treatment of established and advanced tumors in murine tumor models.
Topics: Animals; Cyclophosphamide; Cytosine; Drug Synergism; Female; Interferon Inducers; Lung Neoplasms; Mi | 1987 |
Site-specific antitumour effects of 2 pyrimidinone compounds in rats.
Topics: Animals; Antineoplastic Agents; Cytosine; Interferon Inducers; Killer Cells, Natural; Lung Neoplasms | 1986 |