cytosine has been researched along with Brain Disorders in 10 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "The phosphonylmethoxyalkyl derivative (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (HPMPC) was evaluated for its in vivo efficacy in several model infections for herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) and thymidine kinase-deficient (TK-) HSV-1 in mice." | 7.68 | Efficacy of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine in various models of herpes simplex virus infection in mice. ( De Clercq, E; Holý, A, 1991) |
| " Only the virus recovered from the brains of mice treated with HPMPC at a dosage of 50 mg/kg/week had a slightly decreased susceptibility to HPMPC." | 5.29 | Efficacy of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)-cytosine and 9-(1,3-dihydroxy-2-propoxymethyl)-guanine in the treatment of intracerebral murine cytomegalovirus infections in immunocompetent and immunodeficient mice. ( De Clercq, E; Neyts, J; Snoeck, R; Sobis, H; Vandeputte, M, 1993) |
| "The phosphonylmethoxyalkyl derivative (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (HPMPC) was evaluated for its in vivo efficacy in several model infections for herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) and thymidine kinase-deficient (TK-) HSV-1 in mice." | 3.68 | Efficacy of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine in various models of herpes simplex virus infection in mice. ( De Clercq, E; Holý, A, 1991) |
| " Only the virus recovered from the brains of mice treated with HPMPC at a dosage of 50 mg/kg/week had a slightly decreased susceptibility to HPMPC." | 1.29 | Efficacy of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)-cytosine and 9-(1,3-dihydroxy-2-propoxymethyl)-guanine in the treatment of intracerebral murine cytomegalovirus infections in immunocompetent and immunodeficient mice. ( De Clercq, E; Neyts, J; Snoeck, R; Sobis, H; Vandeputte, M, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (50.00) | 18.7374 |
| 1990's | 3 (30.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cheng, Y | 1 |
| Bernstein, A | 1 |
| Chen, D | 1 |
| Jin, P | 1 |
| Pereira, T | 1 |
| Rojas, CP | 1 |
| Garcia-Buitrago, MT | 1 |
| Chandar, J | 1 |
| Abitbol, C | 1 |
| Seeherunvong, W | 1 |
| Rusconi, P | 1 |
| Bruce, JH | 1 |
| Zilleruelò, G | 1 |
| Hanefeld, F | 1 |
| Riehm, H | 1 |
| Bayardelle, P | 1 |
| Giard, N | 1 |
| Maltais, R | 1 |
| Delorme, J | 1 |
| Brazeau, M | 1 |
| Neyts, J | 1 |
| Sobis, H | 1 |
| Snoeck, R | 1 |
| Vandeputte, M | 1 |
| De Clercq, E | 2 |
| Gibson, JS | 1 |
| Slater, JD | 1 |
| Field, HJ | 1 |
| Holý, A | 1 |
| Utz, JP | 1 |
| Roberts, M | 1 |
| Rinaudo, PA | 1 |
| Tilton, RC | 1 |
| Vilinskas, J | 1 |
| Selby, RC | 1 |
| Lopes, NM | 1 |
1 review available for cytosine and Brain Disorders
| Article | Year |
|---|---|
5-Hydroxymethylcytosine: A new player in brain disorders?
Topics: 5-Methylcytosine; Brain Diseases; Cytosine; Humans | 2015 |
9 other studies available for cytosine and Brain Disorders
| Article | Year |
|---|---|
A child with BK virus infection: inadequacy of current therapeutic strategies.
Topics: BK Virus; Brain Diseases; Cardiomyopathies; Child; Cidofovir; Cytosine; Encephalomyelitis; Fatal Out | 2012 |
Therapy of acute lymphoblastic leukaemia in childhood: effects on the nervous system.
Topics: Asparaginase; Blood-Brain Barrier; Brain Diseases; Cyclophosphamide; Cytosine; Drug-Related Side Eff | 1980 |
Success with amphotericin B and 5-fluorocytosine in treating cerebral cryptococcoma accompanying cryptococcal meningitis.
Topics: Adult; Amphotericin B; Brain Diseases; Cryptococcosis; Cytosine; Flucytosine; Humans; Male; Meningit | 1982 |
Efficacy of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)-cytosine and 9-(1,3-dihydroxy-2-propoxymethyl)-guanine in the treatment of intracerebral murine cytomegalovirus infections in immunocompetent and immunodeficient mice.
Topics: Animals; Animals, Newborn; Antiviral Agents; Brain; Brain Diseases; Cidofovir; Cytomegalovirus; Cyto | 1993 |
The activity of (S)-1-[(3-hydroxy-2-phosphonyl methoxy) propyl] cytosine (HPMPC) against equine herpesvirus-1 (EHV-1) in cell cultures, mice and horses.
Topics: Administration, Intranasal; Animals; Antiviral Agents; Brain Diseases; Cidofovir; Cytosine; Drug Adm | 1992 |
Efficacy of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine in various models of herpes simplex virus infection in mice.
Topics: Acyclovir; Animals; Antiviral Agents; Brain Diseases; Cidofovir; Cytosine; Herpes Simplex; Mice; Mic | 1991 |
Current and future chemotherapy of central nervous system fungal infections.
Topics: Administration, Oral; Amphotericin B; Arrhythmias, Cardiac; Brain Diseases; Cytosine; Flucytosine; G | 1974 |
Treatment of multiple intracerebral cryptococcal granulomas with 5-fluorocytosine. Case report.
Topics: Adult; Antifungal Agents; Brain; Brain Diseases; Cryptococcosis; Cryptococcus neoformans; Cytosine; | 1972 |
Torulomas (cryptococcal granulomata) of the central nervous system.
Topics: Adult; Amphotericin B; Brain Diseases; Central Nervous System Diseases; Cryptococcosis; Cytosine; Fl | 1973 |