cytosine has been researched along with Blood Pressure, High in 30 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Patients with mild-to-moderate primary hypertension and left ventricular hypertrophy were randomized in a double-blind study to receive treatment with either the angiotensin II type 1 (AT1) receptor antagonist irbesartan (n = 43), or the beta1-adrenergic receptor blocker atenolol (n = 43)." | 9.10 | Aldosterone synthase (CYP11B2) -344 C/T polymorphism is related to antihypertensive response: result from the Swedish Irbesartan Left Ventricular Hypertrophy Investigation versus Atenolol (SILVHIA) trial. ( Hägg, A; Kahan, T; Karlsson, J; Kurland, L; Lind, L; Malmqvist, K; Melhus, H; Nyström, F; Ohman, P, 2002) |
| "The angiotensinogen (AGT) gene has been implicated as a risk factor in essential hypertension." | 5.33 | Angiotensinogen promoter sequence variants in essential hypertension. ( Guruju, M; Kumar, A; Prater, A; Velez, DR; Vinukonda, G; Williams, SM, 2006) |
| "Patients with mild-to-moderate primary hypertension and left ventricular hypertrophy were randomized in a double-blind study to receive treatment with either the angiotensin II type 1 (AT1) receptor antagonist irbesartan (n = 43), or the beta1-adrenergic receptor blocker atenolol (n = 43)." | 5.10 | Aldosterone synthase (CYP11B2) -344 C/T polymorphism is related to antihypertensive response: result from the Swedish Irbesartan Left Ventricular Hypertrophy Investigation versus Atenolol (SILVHIA) trial. ( Hägg, A; Kahan, T; Karlsson, J; Kurland, L; Lind, L; Malmqvist, K; Melhus, H; Nyström, F; Ohman, P, 2002) |
| "A thymidine-to-cytosine substitution in the -344 promoter region of the aldosterone synthase gene (CYP11B2) has been associated with essential hypertension in some but not all studies conducted in Chinese." | 4.85 | Association between aldosterone synthase CYP11B2 polymorphism and essential hypertension in Chinese: a meta-analysis. ( Cheng, X; Xu, G, 2009) |
| " Given the potential importance of epigenetic events in hypertension, we have analyzed 5hmC and 5-methylcytosine (5mC) at single-base resolution in the renal outer medulla of the Dahl salt-sensitive rat and examined the effect of disease-relevant genetic or environmental alterations on 5hmC and 5mC patterns." | 3.80 | Base-resolution maps of 5-methylcytosine and 5-hydroxymethylcytosine in Dahl S rats: effect of salt and genomic sequence. ( Cowley, AW; Liang, M; Liu, P; Liu, Y; Yang, C, 2014) |
| " The adenine/cytosine(1166) (A/C(1166)) polymorphism of the AGT1R gene has been shown to be associated with hypertension and hypertension-related diseases." | 3.75 | Adenine/cytosine(1166) polymorphism of the angiotensin II type 1 receptor gene and the antihypertensive response to angiotensin-converting enzyme inhibitors. ( Jin, L; Lin, S; Liu, G; Yu, H; Yu, Y; Zhang, Y; Zhong, J, 2009) |
| "Hypertension is a very common cardiovascular disease influenced by multiple genetic and environmental factors." | 1.40 | Molecular characterization of a Chinese family carrying a novel C4329A mutation in mitochondrial tRNAIle and tRNAGln genes. ( Chen, Y; Gao, J; Guan, M; Lan, Y; Li, Y; Li, Z; Liu, Y; Yang, J; Zhu, C, 2014) |
| "Coronary heart disease (CHD) and chronic periodontitis (CP) both are multifactorial chronic diseases and related to inflammation." | 1.37 | Coronary heart disease and chronic periodontitis: is polymorphism of interleukin-6 gene the common risk factor in a Chinese population? ( Fan, WH; Liu, DL; Sun, SY; Xiao, LM; Xie, CJ; Zhang, JC, 2011) |
| "The etiology of preeclampsia (PE) is unknown, but endothelial cell injury plays a pivotal role." | 1.33 | Association of apolipoprotein J gene 866C-->T polymorphism with preeclampsia and essential hypertension. ( Chen, M; Shan, K; Yuan, Z, 2005) |
| "The angiotensinogen (AGT) gene has been implicated as a risk factor in essential hypertension." | 1.33 | Angiotensinogen promoter sequence variants in essential hypertension. ( Guruju, M; Kumar, A; Prater, A; Velez, DR; Vinukonda, G; Williams, SM, 2006) |
| "Treatment with atenolol did not change PIP and KLV in either subgroup of hypertensives." | 1.32 | The A1166C polymorphism of the AT1 receptor gene is associated with collagen type I synthesis and myocardial stiffness in hypertensives. ( Beloqui, O; Díez, J; González, A; Laviades, C; López, B; Mayor, G; Orbe, J; Páramo, JA; Zalba, G, 2003) |
| "A cytosine deletion was identified by genomic DNA sequencing of the apo A-I gene of the patient at the third base of codon 184 in the fourth exon, which led to a frame shift mutation and early termination at codon 200." | 1.31 | Apolipoprotein A-I deficiency with accumulated risk for CHD but no symptoms of CHD. ( Hashimoto, Y; Kawamura, M; Kitamura, K; Kotani, K; Mashige, F; Nakahara, K; Okubo, S; Shimada, S; Usuki, Y; Yokota, H; Yumoto, M, 2002) |
| "Hypertension is a common multifactorial disorder associated with considerable morbidity and mortality." | 1.30 | The diagnosis of Liddle syndrome by identification of a mutation in the beta subunit of the epithelial sodium channel. ( Houtman, P; Jackson, SN; Trembath, RC; Williams, B, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.33) | 18.7374 |
| 1990's | 2 (6.67) | 18.2507 |
| 2000's | 23 (76.67) | 29.6817 |
| 2010's | 4 (13.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, Y | 2 |
| Liu, P | 1 |
| Yang, C | 1 |
| Cowley, AW | 1 |
| Liang, M | 1 |
| Li, Y | 1 |
| Gao, J | 1 |
| Zhu, C | 1 |
| Lan, Y | 1 |
| Yang, J | 2 |
| Li, Z | 1 |
| Guan, M | 1 |
| Chen, Y | 2 |
| Cheng, X | 1 |
| Xu, G | 1 |
| Yu, H | 1 |
| Lin, S | 1 |
| Jin, L | 1 |
| Yu, Y | 1 |
| Zhong, J | 1 |
| Zhang, Y | 1 |
| Liu, G | 1 |
| Fan, WH | 1 |
| Liu, DL | 1 |
| Xiao, LM | 1 |
| Xie, CJ | 1 |
| Sun, SY | 1 |
| Zhang, JC | 1 |
| Pigossi, SC | 1 |
| Alvim-Pereira, F | 1 |
| Montes, CC | 1 |
| Finoti, LS | 1 |
| Secolin, R | 1 |
| Trevilatto, PC | 1 |
| Scarel-Caminaga, RM | 1 |
| Beige, J | 1 |
| Kreutz, R | 1 |
| Tscherkaschina, I | 1 |
| Scherer, S | 1 |
| Sharma, AM | 1 |
| Zidek, W | 1 |
| Offermann, G | 1 |
| Jin, JJ | 1 |
| Nakura, J | 1 |
| Wu, Z | 1 |
| Yamamoto, M | 1 |
| Abe, M | 1 |
| Tabara, Y | 1 |
| Yamamoto, Y | 1 |
| Igase, M | 1 |
| Bo, X | 1 |
| Kohara, K | 1 |
| Miki, T | 1 |
| Díez, J | 1 |
| Laviades, C | 1 |
| Orbe, J | 1 |
| Zalba, G | 1 |
| López, B | 1 |
| González, A | 1 |
| Mayor, G | 1 |
| Páramo, JA | 1 |
| Beloqui, O | 1 |
| Huang, G | 1 |
| Niu, T | 1 |
| Peng, S | 1 |
| Ling, D | 1 |
| Liu, J | 1 |
| Zhang, X | 1 |
| Xu, X | 1 |
| Zhang, L | 1 |
| Rao, F | 1 |
| Wessel, J | 1 |
| Kennedy, BP | 1 |
| Rana, BK | 1 |
| Taupenot, L | 1 |
| Lillie, EO | 1 |
| Cockburn, M | 1 |
| Schork, NJ | 1 |
| Ziegler, MG | 1 |
| O'Connor, DT | 1 |
| Wojciechowska, W | 1 |
| Staessen, JA | 1 |
| Stolarz, K | 1 |
| Nawrot, T | 1 |
| Filipovský, J | 1 |
| Tichá, M | 1 |
| Bianchi, G | 2 |
| Brand, E | 1 |
| Cwynar, M | 1 |
| Grodzicki, T | 1 |
| Kuznetsova, T | 1 |
| Struijker-Boudier, HA | 1 |
| Svobodová, V | 1 |
| Thijs, L | 1 |
| Van Bortel, LM | 1 |
| Kawecka-Jaszcz, K | 1 |
| Renner, W | 1 |
| Grammer, T | 1 |
| Hoffmann, MM | 1 |
| Nauck, MS | 1 |
| Winkelmann, BR | 1 |
| Boehm, BO | 1 |
| März, W | 1 |
| Jeng, JR | 1 |
| Wang, JH | 1 |
| Liu, WS | 1 |
| Chen, SP | 1 |
| Chen, MY | 1 |
| Wu, MH | 1 |
| Hsu, WL | 1 |
| Lin, SZ | 1 |
| Chen, M | 1 |
| Yuan, Z | 1 |
| Shan, K | 1 |
| Semplicini, A | 1 |
| Lenzini, L | 1 |
| Sartori, M | 1 |
| Papparella, I | 1 |
| Calò, LA | 1 |
| Pagnin, E | 1 |
| Strapazzon, G | 1 |
| Benna, C | 1 |
| Costa, R | 1 |
| Avogaro, A | 1 |
| Ceolotto, G | 1 |
| Pessina, AC | 1 |
| Rubattu, S | 1 |
| Bigatti, G | 1 |
| Evangelista, A | 1 |
| Lanzani, C | 1 |
| Stanzione, R | 1 |
| Zagato, L | 1 |
| Manunta, P | 1 |
| Marchitti, S | 1 |
| Venturelli, V | 1 |
| Volpe, M | 1 |
| Stella, P | 1 |
| Sookoian, S | 1 |
| Gianotti, TF | 1 |
| González, CD | 1 |
| Pirola, CJ | 1 |
| Kamide, K | 1 |
| Kokubo, Y | 1 |
| Matayoshi, T | 1 |
| Inamoto, N | 1 |
| Takiuchi, S | 1 |
| Horio, T | 1 |
| Miwa, Y | 1 |
| Yoshii, M | 1 |
| Tomoike, H | 1 |
| Tanaka, C | 1 |
| Banno, M | 1 |
| Okuda, T | 1 |
| Kawano, Y | 1 |
| Miyata, T | 1 |
| Velez, DR | 1 |
| Guruju, M | 1 |
| Vinukonda, G | 1 |
| Prater, A | 1 |
| Kumar, A | 1 |
| Williams, SM | 1 |
| Markan, S | 1 |
| Sachdeva, M | 1 |
| Sehrawat, BS | 1 |
| Kumari, S | 1 |
| Jain, S | 1 |
| Khullar, M | 1 |
| Qian, X | 1 |
| Lu, Z | 1 |
| Tan, M | 1 |
| Liu, H | 1 |
| Lu, D | 1 |
| Hu, BC | 1 |
| Chu, SL | 1 |
| Wang, GL | 1 |
| Gao, PJ | 1 |
| Zhu, DL | 1 |
| Wang, JG | 1 |
| Jackson, SN | 1 |
| Williams, B | 1 |
| Houtman, P | 1 |
| Trembath, RC | 1 |
| Inoue, T | 1 |
| Okauchi, Y | 1 |
| Matsuzaki, Y | 1 |
| Kuwajima, K | 1 |
| Kondo, H | 1 |
| Horiuchi, N | 1 |
| Nakao, K | 1 |
| Iwata, M | 1 |
| Yokogoshi, Y | 1 |
| Shintani, Y | 1 |
| Bando, H | 1 |
| Saito, S | 1 |
| Zdrojewicz, Z | 1 |
| Sztuka-Pietkiewicz, A | 1 |
| Revilla, M | 1 |
| Obach, V | 1 |
| Cervera, A | 1 |
| Dávalos, A | 1 |
| Castillo, J | 1 |
| Chamorro, A | 1 |
| Yokota, H | 1 |
| Hashimoto, Y | 1 |
| Okubo, S | 1 |
| Yumoto, M | 1 |
| Mashige, F | 1 |
| Kawamura, M | 1 |
| Kotani, K | 1 |
| Usuki, Y | 1 |
| Shimada, S | 1 |
| Kitamura, K | 1 |
| Nakahara, K | 1 |
| Kurland, L | 1 |
| Melhus, H | 1 |
| Karlsson, J | 1 |
| Kahan, T | 1 |
| Malmqvist, K | 1 |
| Ohman, P | 1 |
| Nyström, F | 1 |
| Hägg, A | 1 |
| Lind, L | 1 |
| Tay, CH | 1 |
| Chew, WL | 1 |
| Lim, LC | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Physiological and Psychological Effects of Testosterone During Severe Energy Deficit and Recovery: a Randomized, Placebo Controlled Trial[NCT02734238] | Phase 4 | 53 participants (Actual) | Interventional | 2016-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Height was measured using a stadiometer. Weight was measured using a calibrated digital scale. Body composition was determined using dual-energy X-ray absorptiometry. These data were used to calculate fat-free body mass, fat mass, and total body tissue mass. (NCT02734238)
Timeframe: end of each study phase: Day 11 for Phase 1, Day 39 for Phase 2, up to Day 85 for Phase 3
| Intervention | kilograms (Least Squares Mean) | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Total Body Mass at end of Phase 1 | Total Body Mass at end of Phase 2 | Total Body Mass at end of Phase 3 | Fat-free Mass at end of Phase 1 | Fat-free Mass at end of Phase 2 | Fat-free Mass at end of Phase 3 | Fat Mass at end of Phase 1 | Fat Mass at end of Phase 2 | Fat Mass at end of Phase 3 | |
| Energy Deficit | 78.3 | 73.3 | 76.5 | 58.3 | 58.0 | 60.5 | 16.8 | 12.2 | 12.8 |
| Energy Deficit + Testosterone | 78.0 | 75.8 | 79.3 | 57.9 | 60.4 | 63.1 | 16.8 | 12.0 | 12.8 |
5 reviews available for cytosine and Blood Pressure, High
| Article | Year |
|---|---|
Association between aldosterone synthase CYP11B2 polymorphism and essential hypertension in Chinese: a meta-analysis.
Topics: Asian People; Cytochrome P-450 CYP11B2; Cytosine; Humans; Hypertension; Polymorphism, Genetic; Promo | 2009 |
Association of the C-344T aldosterone synthase gene variant with essential hypertension: a meta-analysis.
Topics: Aldosterone; Blood Pressure; Case-Control Studies; Cohort Studies; Cross-Sectional Studies; Cytochro | 2007 |
A meta-analysis of association between C677T polymorphism in the methylenetetrahydrofolate reductase gene and hypertension.
Topics: Asian People; Bias; Cytosine; Genetic Predisposition to Disease; Heterozygote; Humans; Hypertension; | 2007 |
Identification of a single cytosine base insertion mutation at Arg-597 of the beta subunit of the human epithelial sodium channel in a family with Liddle's disease.
Topics: Adolescent; Adult; Amino Acid Sequence; Amino Acid Substitution; Arginine; Base Sequence; Cytosine; | 1998 |
[The role of beta 3-adrenergic receptors in the human organism].
Topics: Arginine; Coronary Disease; Cytosine; Diabetes Mellitus; Energy Metabolism; Humans; Hypertension; Li | 2001 |
3 trials available for cytosine and Blood Pressure, High
| Article | Year |
|---|---|
Association of angiotensin II type 2 receptor gene variant with hypertension.
Topics: Adenine; Adult; Asian People; Blood Pressure; Cytosine; Female; Genetic Variation; Genotype; Humans; | 2003 |
MTHFR 677 CT/MTHFR 1298 CC genotypes are associated with increased risk of hypertension in Indians.
Topics: Asian People; Case-Control Studies; Cytosine; Female; Folic Acid; Gene Frequency; Genetic Predisposi | 2007 |
Aldosterone synthase (CYP11B2) -344 C/T polymorphism is related to antihypertensive response: result from the Swedish Irbesartan Left Ventricular Hypertrophy Investigation versus Atenolol (SILVHIA) trial.
Topics: Adrenergic beta-Antagonists; Aldosterone; Angiotensin Receptor Antagonists; Antihypertensive Agents; | 2002 |
22 other studies available for cytosine and Blood Pressure, High
| Article | Year |
|---|---|
Base-resolution maps of 5-methylcytosine and 5-hydroxymethylcytosine in Dahl S rats: effect of salt and genomic sequence.
Topics: 5-Methylcytosine; Animals; Base Sequence; CpG Islands; Cytosine; Disease Models, Animal; Epigenomics | 2014 |
Molecular characterization of a Chinese family carrying a novel C4329A mutation in mitochondrial tRNAIle and tRNAGln genes.
Topics: Asian People; Case-Control Studies; Cytosine; DNA, Mitochondrial; Female; Genetic Predisposition to | 2014 |
Adenine/cytosine(1166) polymorphism of the angiotensin II type 1 receptor gene and the antihypertensive response to angiotensin-converting enzyme inhibitors.
Topics: Adenosine; Angiotensin-Converting Enzyme Inhibitors; Cohort Studies; Cytosine; Humans; Hypertension; | 2009 |
Coronary heart disease and chronic periodontitis: is polymorphism of interleukin-6 gene the common risk factor in a Chinese population?
Topics: Adenine; Adult; Aged; Alcohol Drinking; Case-Control Studies; China; Chromosome Mapping; Chronic Per | 2011 |
Genetic association study between Interleukin 10 gene and dental implant loss.
Topics: Adenine; Alleles; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular | 2012 |
Matrix analysis for the dissection of interactions of G-protein beta3 subunit C825T genotype, allograft function, and posttransplant hypertension in kidney transplantation.
Topics: Adult; Cytosine; Female; Follow-Up Studies; Genotype; Graft Survival; Heterotrimeric GTP-Binding Pro | 2002 |
The A1166C polymorphism of the AT1 receptor gene is associated with collagen type I synthesis and myocardial stiffness in hypertensives.
Topics: Adenine; Adult; Aged; Alleles; Antihypertensive Agents; Atenolol; Collagen Type I; Cytosine; Elastic | 2003 |
Association between the interleukin-1beta C(-511)T polymorphism and blood pressure in a Chinese hypertensive population.
Topics: Asian People; Blood Pressure; Cytosine; Female; Genetic Predisposition to Disease; Humans; Hypertens | 2004 |
Functional allelic heterogeneity and pleiotropy of a repeat polymorphism in tyrosine hydroxylase: prediction of catecholamines and response to stress in twins.
Topics: Adenine; Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Alleles; Autonomic Nervous System; | 2004 |
Association of peripheral and central arterial wave reflections with the CYP11B2 -344C allele and sodium excretion.
Topics: Adult; Alleles; Arteries; Blood Pressure; Cytochrome P-450 CYP11B2; Cytosine; DNA Transposable Eleme | 2004 |
Association analysis of the polymorphism T1128C in the signal peptide of neuropeptide Y in a Swedish hypertensive population.
Topics: Cytosine; Humans; Hypertension; Neuropeptide Y; Polymorphism, Genetic; Protein Sorting Signals; Swed | 2004 |
Association of interleukin-6 gene G-174C polymorphism and plasma plasminogen activator inhibitor-1 level in Chinese patients with and without hypertension.
Topics: Adult; Asian People; Case-Control Studies; Cytosine; Female; Gene Frequency; Genotype; Guanine; Huma | 2005 |
Association of apolipoprotein J gene 866C-->T polymorphism with preeclampsia and essential hypertension.
Topics: Adult; Amino Acid Sequence; Case-Control Studies; China; Clusterin; Cytosine; DNA Mutational Analysi | 2005 |
Reduced expression of regulator of G-protein signaling 2 (RGS2) in hypertensive patients increases calcium mobilization and ERK1/2 phosphorylation induced by angiotensin II.
Topics: Adult; Angiotensin II; Calcium; Cells, Cultured; Cytosine; Extracellular Signal-Regulated MAP Kinase | 2006 |
Association of atrial natriuretic peptide and type a natriuretic peptide receptor gene polymorphisms with left ventricular mass in human essential hypertension.
Topics: Adenine; Adult; Alleles; Atrial Natriuretic Factor; Cytosine; Echocardiography; Female; Genetic Vari | 2006 |
Association of genetic polymorphisms of ACADSB and COMT with human hypertension.
Topics: Acyl-CoA Dehydrogenases; Adenine; Aged; Asian People; Blood Pressure; Cohort Studies; Cytosine; DNA- | 2007 |
Angiotensinogen promoter sequence variants in essential hypertension.
Topics: Adenine; Angiotensinogen; Black or African American; Cohort Studies; Cytosine; Female; Gene Frequenc | 2006 |
Association between genetic variation in transforming growth factors beta1 and beta3 and renal dysfunction in non-diabetic Chinese.
Topics: Adenine; Adult; Aged; Aged, 80 and over; Albuminuria; Asian People; Creatinine; Cytosine; Female; Ge | 2008 |
The diagnosis of Liddle syndrome by identification of a mutation in the beta subunit of the epithelial sodium channel.
Topics: Aldosterone; Alleles; Amino Acid Sequence; Base Sequence; Blood Pressure; Chromosome Mapping; Chromo | 1998 |
A -174G/C polymorphism of the interleukin-6 gene in patients with lacunar infarction.
Topics: Aged; Brain; Brain Ischemia; Cerebral Infarction; Cohort Studies; Cytosine; Diabetes Complications; | 2002 |
Apolipoprotein A-I deficiency with accumulated risk for CHD but no symptoms of CHD.
Topics: Aged; Amino Acid Sequence; Apolipoprotein A-I; Apolipoproteins E; Base Sequence; Cholesterol, HDL; C | 2002 |
Cryptococcal meningitis: its apparent increased incidence in the Far East.
Topics: Adolescent; Adult; Amphotericin B; Animals; Asian People; Cerebrospinal Fluid Proteins; Child; Colum | 1972 |